Amino acid dipepetide frequency for Sulfurimonas autotrophica (strain ATCC BAA-671 / DSM 16294 / JCM 11897 / OK10)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.802AlaAla: 4.802 ± 0.108
0.667AlaCys: 0.667 ± 0.038
3.603AlaAsp: 3.603 ± 0.085
3.479AlaGlu: 3.479 ± 0.08
3.345AlaPhe: 3.345 ± 0.077
4.205AlaGly: 4.205 ± 0.089
1.459AlaHis: 1.459 ± 0.048
5.73AlaIle: 5.73 ± 0.103
6.67AlaLys: 6.67 ± 0.115
7.985AlaLeu: 7.985 ± 0.123
2.171AlaMet: 2.171 ± 0.07
3.397AlaAsn: 3.397 ± 0.069
2.003AlaPro: 2.003 ± 0.066
2.892AlaGln: 2.892 ± 0.069
2.369AlaArg: 2.369 ± 0.058
4.376AlaSer: 4.376 ± 0.082
3.675AlaThr: 3.675 ± 0.079
4.612AlaVal: 4.612 ± 0.102
0.464AlaTrp: 0.464 ± 0.028
2.886AlaTyr: 2.886 ± 0.069
0.0AlaXaa: 0.0 ± 0.0
Cys
0.609CysAla: 0.609 ± 0.028
0.091CysCys: 0.091 ± 0.013
0.64CysAsp: 0.64 ± 0.034
0.701CysGlu: 0.701 ± 0.034
0.322CysPhe: 0.322 ± 0.023
0.722CysGly: 0.722 ± 0.037
0.305CysHis: 0.305 ± 0.031
0.548CysIle: 0.548 ± 0.028
0.73CysLys: 0.73 ± 0.037
0.508CysLeu: 0.508 ± 0.028
0.229CysMet: 0.229 ± 0.019
0.471CysAsn: 0.471 ± 0.028
0.388CysPro: 0.388 ± 0.03
0.241CysGln: 0.241 ± 0.022
0.26CysArg: 0.26 ± 0.018
0.624CysSer: 0.624 ± 0.035
0.392CysThr: 0.392 ± 0.026
0.456CysVal: 0.456 ± 0.025
0.055CysTrp: 0.055 ± 0.01
0.284CysTyr: 0.284 ± 0.022
0.0CysXaa: 0.0 ± 0.0
Asp
4.508AspAla: 4.508 ± 0.09
0.423AspCys: 0.423 ± 0.024
3.236AspAsp: 3.236 ± 0.073
5.404AspGlu: 5.404 ± 0.103
3.137AspPhe: 3.137 ± 0.071
3.334AspGly: 3.334 ± 0.078
0.618AspHis: 0.618 ± 0.028
5.666AspIle: 5.666 ± 0.106
4.828AspLys: 4.828 ± 0.09
4.884AspLeu: 4.884 ± 0.093
1.658AspMet: 1.658 ± 0.053
2.684AspAsn: 2.684 ± 0.072
1.321AspPro: 1.321 ± 0.048
0.847AspGln: 0.847 ± 0.035
1.629AspArg: 1.629 ± 0.048
2.843AspSer: 2.843 ± 0.066
3.195AspThr: 3.195 ± 0.062
3.854AspVal: 3.854 ± 0.076
0.41AspTrp: 0.41 ± 0.024
2.374AspTyr: 2.374 ± 0.068
0.0AspXaa: 0.0 ± 0.0
Glu
5.045GluAla: 5.045 ± 0.101
0.654GluCys: 0.654 ± 0.035
3.84GluAsp: 3.84 ± 0.084
5.138GluGlu: 5.138 ± 0.124
3.221GluPhe: 3.221 ± 0.081
3.377GluGly: 3.377 ± 0.082
1.626GluHis: 1.626 ± 0.051
5.908GluIle: 5.908 ± 0.102
6.397GluLys: 6.397 ± 0.108
7.41GluLeu: 7.41 ± 0.131
1.96GluMet: 1.96 ± 0.052
4.172GluAsn: 4.172 ± 0.079
1.584GluPro: 1.584 ± 0.045
2.224GluGln: 2.224 ± 0.056
2.25GluArg: 2.25 ± 0.068
3.623GluSer: 3.623 ± 0.078
2.773GluThr: 2.773 ± 0.073
4.557GluVal: 4.557 ± 0.088
0.539GluTrp: 0.539 ± 0.029
3.025GluTyr: 3.025 ± 0.072
0.0GluXaa: 0.0 ± 0.0
Phe
3.398PheAla: 3.398 ± 0.08
0.467PheCys: 0.467 ± 0.026
3.076PheAsp: 3.076 ± 0.071
3.284PheGlu: 3.284 ± 0.07
2.574PhePhe: 2.574 ± 0.078
3.279PheGly: 3.279 ± 0.079
0.886PheHis: 0.886 ± 0.036
4.125PheIle: 4.125 ± 0.096
3.473PheLys: 3.473 ± 0.075
4.777PheLeu: 4.777 ± 0.095
1.363PheMet: 1.363 ± 0.053
2.351PheAsn: 2.351 ± 0.073
1.125PhePro: 1.125 ± 0.039
1.082PheGln: 1.082 ± 0.044
1.407PheArg: 1.407 ± 0.042
3.624PheSer: 3.624 ± 0.079
2.744PheThr: 2.744 ± 0.065
3.186PheVal: 3.186 ± 0.072
0.453PheTrp: 0.453 ± 0.03
2.012PheTyr: 2.012 ± 0.06
0.0PheXaa: 0.0 ± 0.0
Gly
4.256GlyAla: 4.256 ± 0.094
0.689GlyCys: 0.689 ± 0.037
3.085GlyAsp: 3.085 ± 0.061
3.712GlyGlu: 3.712 ± 0.088
3.268GlyPhe: 3.268 ± 0.069
3.884GlyGly: 3.884 ± 0.098
1.262GlyHis: 1.262 ± 0.041
5.033GlyIle: 5.033 ± 0.093
4.43GlyLys: 4.43 ± 0.099
5.223GlyLeu: 5.223 ± 0.105
1.663GlyMet: 1.663 ± 0.059
2.364GlyAsn: 2.364 ± 0.073
0.955GlyPro: 0.955 ± 0.039
1.372GlyGln: 1.372 ± 0.048
1.993GlyArg: 1.993 ± 0.061
3.479GlySer: 3.479 ± 0.085
2.881GlyThr: 2.881 ± 0.08
4.511GlyVal: 4.511 ± 0.092
0.55GlyTrp: 0.55 ± 0.032
2.681GlyTyr: 2.681 ± 0.072
0.0GlyXaa: 0.0 ± 0.0
His
1.235HisAla: 1.235 ± 0.04
0.178HisCys: 0.178 ± 0.016
1.079HisAsp: 1.079 ± 0.044
1.291HisGlu: 1.291 ± 0.047
1.128HisPhe: 1.128 ± 0.04
1.19HisGly: 1.19 ± 0.044
0.517HisHis: 0.517 ± 0.028
1.722HisIle: 1.722 ± 0.051
1.599HisLys: 1.599 ± 0.053
1.801HisLeu: 1.801 ± 0.053
0.496HisMet: 0.496 ± 0.027
1.137HisAsn: 1.137 ± 0.036
0.948HisPro: 0.948 ± 0.04
0.678HisGln: 0.678 ± 0.03
0.679HisArg: 0.679 ± 0.033
1.165HisSer: 1.165 ± 0.037
1.15HisThr: 1.15 ± 0.043
1.374HisVal: 1.374 ± 0.051
0.156HisTrp: 0.156 ± 0.014
0.862HisTyr: 0.862 ± 0.037
0.0HisXaa: 0.0 ± 0.0
Ile
6.589IleAla: 6.589 ± 0.126
0.697IleCys: 0.697 ± 0.037
5.482IleAsp: 5.482 ± 0.093
5.901IleGlu: 5.901 ± 0.113
3.893IlePhe: 3.893 ± 0.096
4.89IleGly: 4.89 ± 0.092
1.41IleHis: 1.41 ± 0.049
6.694IleIle: 6.694 ± 0.127
6.921IleLys: 6.921 ± 0.128
7.575IleLeu: 7.575 ± 0.128
1.874IleMet: 1.874 ± 0.055
4.507IleAsn: 4.507 ± 0.098
2.66IlePro: 2.66 ± 0.062
2.603IleGln: 2.603 ± 0.06
2.484IleArg: 2.484 ± 0.061
5.545IleSer: 5.545 ± 0.106
4.575IleThr: 4.575 ± 0.082
5.55IleVal: 5.55 ± 0.106
0.513IleTrp: 0.513 ± 0.03
3.193IleTyr: 3.193 ± 0.079
0.0IleXaa: 0.0 ± 0.0
Lys
5.609LysAla: 5.609 ± 0.1
0.581LysCys: 0.581 ± 0.034
4.854LysAsp: 4.854 ± 0.089
8.233LysGlu: 8.233 ± 0.137
3.086LysPhe: 3.086 ± 0.071
3.82LysGly: 3.82 ± 0.075
1.669LysHis: 1.669 ± 0.045
7.409LysIle: 7.409 ± 0.111
8.745LysLys: 8.745 ± 0.179
7.679LysLeu: 7.679 ± 0.103
2.453LysMet: 2.453 ± 0.062
5.788LysAsn: 5.788 ± 0.102
2.532LysPro: 2.532 ± 0.064
2.755LysGln: 2.755 ± 0.075
3.229LysArg: 3.229 ± 0.072
5.116LysSer: 5.116 ± 0.099
4.416LysThr: 4.416 ± 0.074
5.003LysVal: 5.003 ± 0.102
0.533LysTrp: 0.533 ± 0.031
3.639LysTyr: 3.639 ± 0.075
0.0LysXaa: 0.0 ± 0.0
Leu
6.575LeuAla: 6.575 ± 0.116
0.773LeuCys: 0.773 ± 0.033
5.652LeuAsp: 5.652 ± 0.098
6.574LeuGlu: 6.574 ± 0.118
5.126LeuPhe: 5.126 ± 0.106
5.584LeuGly: 5.584 ± 0.113
2.41LeuHis: 2.41 ± 0.064
7.028LeuIle: 7.028 ± 0.11
8.496LeuLys: 8.496 ± 0.12
9.774LeuLeu: 9.774 ± 0.146
2.418LeuMet: 2.418 ± 0.064
5.031LeuAsn: 5.031 ± 0.091
3.195LeuPro: 3.195 ± 0.069
3.728LeuGln: 3.728 ± 0.082
3.083LeuArg: 3.083 ± 0.066
7.152LeuSer: 7.152 ± 0.117
4.768LeuThr: 4.768 ± 0.077
5.593LeuVal: 5.593 ± 0.111
0.698LeuTrp: 0.698 ± 0.038
3.828LeuTyr: 3.828 ± 0.08
0.0LeuXaa: 0.0 ± 0.0
Met
2.013MetAla: 2.013 ± 0.055
0.186MetCys: 0.186 ± 0.015
1.389MetAsp: 1.389 ± 0.046
1.284MetGlu: 1.284 ± 0.037
1.046MetPhe: 1.046 ± 0.045
1.709MetGly: 1.709 ± 0.05
0.632MetHis: 0.632 ± 0.027
2.196MetIle: 2.196 ± 0.06
2.473MetLys: 2.473 ± 0.058
2.762MetLeu: 2.762 ± 0.072
0.817MetMet: 0.817 ± 0.037
1.443MetAsn: 1.443 ± 0.043
1.094MetPro: 1.094 ± 0.036
1.325MetGln: 1.325 ± 0.045
0.899MetArg: 0.899 ± 0.035
1.99MetSer: 1.99 ± 0.059
1.201MetThr: 1.201 ± 0.038
1.541MetVal: 1.541 ± 0.048
0.171MetTrp: 0.171 ± 0.017
0.762MetTyr: 0.762 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
3.832AsnAla: 3.832 ± 0.092
0.403AsnCys: 0.403 ± 0.025
2.878AsnAsp: 2.878 ± 0.064
3.856AsnGlu: 3.856 ± 0.082
2.591AsnPhe: 2.591 ± 0.064
2.991AsnGly: 2.991 ± 0.079
0.95AsnHis: 0.95 ± 0.038
5.548AsnIle: 5.548 ± 0.097
4.476AsnLys: 4.476 ± 0.109
4.676AsnLeu: 4.676 ± 0.089
1.328AsnMet: 1.328 ± 0.049
2.808AsnAsn: 2.808 ± 0.066
2.028AsnPro: 2.028 ± 0.056
1.431AsnGln: 1.431 ± 0.053
1.773AsnArg: 1.773 ± 0.052
3.294AsnSer: 3.294 ± 0.076
2.725AsnThr: 2.725 ± 0.072
3.107AsnVal: 3.107 ± 0.068
0.319AsnTrp: 0.319 ± 0.021
2.098AsnTyr: 2.098 ± 0.061
0.0AsnXaa: 0.0 ± 0.0
Pro
1.768ProAla: 1.768 ± 0.052
0.22ProCys: 0.22 ± 0.02
1.645ProAsp: 1.645 ± 0.048
1.945ProGlu: 1.945 ± 0.06
1.664ProPhe: 1.664 ± 0.054
1.26ProGly: 1.26 ± 0.05
0.722ProHis: 0.722 ± 0.032
2.415ProIle: 2.415 ± 0.064
2.577ProLys: 2.577 ± 0.071
3.134ProLeu: 3.134 ± 0.073
0.77ProMet: 0.77 ± 0.031
1.53ProAsn: 1.53 ± 0.044
0.802ProPro: 0.802 ± 0.039
1.207ProGln: 1.207 ± 0.044
0.905ProArg: 0.905 ± 0.038
1.862ProSer: 1.862 ± 0.052
1.664ProThr: 1.664 ± 0.053
1.996ProVal: 1.996 ± 0.054
0.232ProTrp: 0.232 ± 0.019
1.394ProTyr: 1.394 ± 0.047
0.0ProXaa: 0.0 ± 0.0
Gln
2.085GlnAla: 2.085 ± 0.066
0.192GlnCys: 0.192 ± 0.017
1.667GlnAsp: 1.667 ± 0.056
2.796GlnGlu: 2.796 ± 0.07
1.162GlnPhe: 1.162 ± 0.038
1.459GlnGly: 1.459 ± 0.046
0.575GlnHis: 0.575 ± 0.034
2.505GlnIle: 2.505 ± 0.06
3.731GlnLys: 3.731 ± 0.084
2.724GlnLeu: 2.724 ± 0.059
0.915GlnMet: 0.915 ± 0.034
2.352GlnAsn: 2.352 ± 0.061
0.786GlnPro: 0.786 ± 0.036
1.061GlnGln: 1.061 ± 0.051
1.318GlnArg: 1.318 ± 0.046
1.817GlnSer: 1.817 ± 0.049
1.902GlnThr: 1.902 ± 0.06
1.517GlnVal: 1.517 ± 0.047
0.257GlnTrp: 0.257 ± 0.021
1.132GlnTyr: 1.132 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
2.334ArgAla: 2.334 ± 0.064
0.273ArgCys: 0.273 ± 0.02
1.938ArgAsp: 1.938 ± 0.055
2.443ArgGlu: 2.443 ± 0.073
1.719ArgPhe: 1.719 ± 0.049
1.863ArgGly: 1.863 ± 0.053
0.724ArgHis: 0.724 ± 0.031
2.611ArgIle: 2.611 ± 0.053
2.437ArgLys: 2.437 ± 0.06
3.172ArgLeu: 3.172 ± 0.078
0.896ArgMet: 0.896 ± 0.034
1.583ArgAsn: 1.583 ± 0.048
0.95ArgPro: 0.95 ± 0.041
0.915ArgGln: 0.915 ± 0.035
1.279ArgArg: 1.279 ± 0.044
1.727ArgSer: 1.727 ± 0.048
1.438ArgThr: 1.438 ± 0.046
2.508ArgVal: 2.508 ± 0.064
0.264ArgTrp: 0.264 ± 0.018
1.58ArgTyr: 1.58 ± 0.054
0.0ArgXaa: 0.0 ± 0.0
Ser
4.291SerAla: 4.291 ± 0.086
0.563SerCys: 0.563 ± 0.029
3.379SerAsp: 3.379 ± 0.076
3.541SerGlu: 3.541 ± 0.068
3.459SerPhe: 3.459 ± 0.075
3.996SerGly: 3.996 ± 0.085
1.302SerHis: 1.302 ± 0.046
5.147SerIle: 5.147 ± 0.096
5.17SerLys: 5.17 ± 0.096
6.606SerLeu: 6.606 ± 0.106
1.685SerMet: 1.685 ± 0.053
2.972SerAsn: 2.972 ± 0.084
1.675SerPro: 1.675 ± 0.048
2.218SerGln: 2.218 ± 0.06
2.085SerArg: 2.085 ± 0.057
4.357SerSer: 4.357 ± 0.094
2.973SerThr: 2.973 ± 0.076
4.039SerVal: 4.039 ± 0.071
0.468SerTrp: 0.468 ± 0.028
2.687SerTyr: 2.687 ± 0.071
0.0SerXaa: 0.0 ± 0.0
Thr
3.655ThrAla: 3.655 ± 0.074
0.539ThrCys: 0.539 ± 0.032
2.593ThrAsp: 2.593 ± 0.067
2.296ThrGlu: 2.296 ± 0.063
2.481ThrPhe: 2.481 ± 0.057
2.975ThrGly: 2.975 ± 0.073
1.126ThrHis: 1.126 ± 0.04
4.161ThrIle: 4.161 ± 0.091
4.4ThrLys: 4.4 ± 0.077
5.849ThrLeu: 5.849 ± 0.107
1.223ThrMet: 1.223 ± 0.045
2.632ThrAsn: 2.632 ± 0.075
2.266ThrPro: 2.266 ± 0.056
2.064ThrGln: 2.064 ± 0.061
1.449ThrArg: 1.449 ± 0.051
3.018ThrSer: 3.018 ± 0.077
3.002ThrThr: 3.002 ± 0.083
3.098ThrVal: 3.098 ± 0.06
0.331ThrTrp: 0.331 ± 0.029
2.055ThrTyr: 2.055 ± 0.063
0.0ThrXaa: 0.0 ± 0.0
Val
4.811ValAla: 4.811 ± 0.103
0.596ValCys: 0.596 ± 0.032
3.823ValAsp: 3.823 ± 0.086
4.113ValGlu: 4.113 ± 0.091
2.776ValPhe: 2.776 ± 0.066
3.917ValGly: 3.917 ± 0.086
1.221ValHis: 1.221 ± 0.039
5.092ValIle: 5.092 ± 0.095
5.245ValLys: 5.245 ± 0.085
6.241ValLeu: 6.241 ± 0.114
1.74ValMet: 1.74 ± 0.057
3.216ValAsn: 3.216 ± 0.068
1.963ValPro: 1.963 ± 0.05
1.887ValGln: 1.887 ± 0.057
1.961ValArg: 1.961 ± 0.056
4.195ValSer: 4.195 ± 0.076
3.284ValThr: 3.284 ± 0.069
4.651ValVal: 4.651 ± 0.102
0.475ValTrp: 0.475 ± 0.028
2.361ValTyr: 2.361 ± 0.067
0.0ValXaa: 0.0 ± 0.0
Trp
0.496TrpAla: 0.496 ± 0.029
0.076TrpCys: 0.076 ± 0.011
0.389TrpAsp: 0.389 ± 0.023
0.4TrpGlu: 0.4 ± 0.028
0.392TrpPhe: 0.392 ± 0.027
0.502TrpGly: 0.502 ± 0.03
0.215TrpHis: 0.215 ± 0.019
0.637TrpIle: 0.637 ± 0.03
0.438TrpLys: 0.438 ± 0.025
0.892TrpLeu: 0.892 ± 0.037
0.294TrpMet: 0.294 ± 0.02
0.343TrpAsn: 0.343 ± 0.026
0.158TrpPro: 0.158 ± 0.018
0.284TrpGln: 0.284 ± 0.023
0.248TrpArg: 0.248 ± 0.021
0.377TrpSer: 0.377 ± 0.024
0.278TrpThr: 0.278 ± 0.021
0.496TrpVal: 0.496 ± 0.025
0.089TrpTrp: 0.089 ± 0.012
0.302TrpTyr: 0.302 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.875TyrAla: 2.875 ± 0.072
0.309TyrCys: 0.309 ± 0.022
2.605TyrAsp: 2.605 ± 0.061
2.935TyrGlu: 2.935 ± 0.072
2.293TyrPhe: 2.293 ± 0.059
2.328TyrGly: 2.328 ± 0.063
0.758TyrHis: 0.758 ± 0.038
3.38TyrIle: 3.38 ± 0.072
3.917TyrLys: 3.917 ± 0.088
3.814TyrLeu: 3.814 ± 0.088
0.978TyrMet: 0.978 ± 0.037
2.334TyrAsn: 2.334 ± 0.064
1.279TyrPro: 1.279 ± 0.049
1.141TyrGln: 1.141 ± 0.039
1.355TyrArg: 1.355 ± 0.046
2.429TyrSer: 2.429 ± 0.066
2.175TyrThr: 2.175 ± 0.064
1.918TyrVal: 1.918 ± 0.05
0.328TyrTrp: 0.328 ± 0.025
1.682TyrTyr: 1.682 ± 0.057
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2155 proteins (672986 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski