Amino acid dipepetide frequency for Bacillus infantis NRRL B-14911

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.38AlaAla: 9.38 ± 0.129	0.621AlaCys: 0.621 ± 0.019	4.381AlaAsp: 4.381 ± 0.063	6.767AlaGlu: 6.767 ± 0.076	3.723AlaPhe: 3.723 ± 0.057	7.634AlaGly: 7.634 ± 0.084	1.266AlaHis: 1.266 ± 0.033	5.568AlaIle: 5.568 ± 0.075	4.585AlaLys: 4.585 ± 0.08	7.549AlaLeu: 7.549 ± 0.083	2.098AlaMet: 2.098 ± 0.046	2.373AlaAsn: 2.373 ± 0.05	2.28AlaPro: 2.28 ± 0.041	2.117AlaGln: 2.117 ± 0.04	3.207AlaArg: 3.207 ± 0.053	4.916AlaSer: 4.916 ± 0.059	2.656AlaThr: 2.656 ± 0.047	6.558AlaVal: 6.558 ± 0.08	0.637AlaTrp: 0.637 ± 0.02	2.417AlaTyr: 2.417 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.436CysAla: 0.436 ± 0.019	0.103CysCys: 0.103 ± 0.01	0.329CysAsp: 0.329 ± 0.017	0.423CysGlu: 0.423 ± 0.02	0.356CysPhe: 0.356 ± 0.015	0.661CysGly: 0.661 ± 0.022	0.181CysHis: 0.181 ± 0.01	0.504CysIle: 0.504 ± 0.02	0.28CysLys: 0.28 ± 0.015	0.752CysLeu: 0.752 ± 0.026	0.18CysMet: 0.18 ± 0.012	0.217CysAsn: 0.217 ± 0.014	0.359CysPro: 0.359 ± 0.017	0.22CysGln: 0.22 ± 0.012	0.431CysArg: 0.431 ± 0.019	0.571CysSer: 0.571 ± 0.02	0.391CysThr: 0.391 ± 0.017	0.362CysVal: 0.362 ± 0.017	0.09CysTrp: 0.09 ± 0.008	0.233CysTyr: 0.233 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	3.548AspAla: 3.548 ± 0.055	0.385AspCys: 0.385 ± 0.018	2.36AspAsp: 2.36 ± 0.046	4.25AspGlu: 4.25 ± 0.066	2.446AspPhe: 2.446 ± 0.044	3.594AspGly: 3.594 ± 0.058	1.056AspHis: 1.056 ± 0.028	3.989AspIle: 3.989 ± 0.058	3.027AspLys: 3.027 ± 0.054	5.028AspLeu: 5.028 ± 0.07	1.396AspMet: 1.396 ± 0.033	1.654AspAsn: 1.654 ± 0.037	2.146AspPro: 2.146 ± 0.044	1.851AspGln: 1.851 ± 0.037	2.459AspArg: 2.459 ± 0.048	3.112AspSer: 3.112 ± 0.041	2.263AspThr: 2.263 ± 0.043	3.179AspVal: 3.179 ± 0.052	0.653AspTrp: 0.653 ± 0.024	2.173AspTyr: 2.173 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.527GluAla: 6.527 ± 0.084	0.434GluCys: 0.434 ± 0.02	4.197GluAsp: 4.197 ± 0.064	8.148GluGlu: 8.148 ± 0.17	2.69GluPhe: 2.69 ± 0.045	5.294GluGly: 5.294 ± 0.069	1.467GluHis: 1.467 ± 0.033	5.431GluIle: 5.431 ± 0.066	6.996GluLys: 6.996 ± 0.081	7.387GluLeu: 7.387 ± 0.081	2.465GluMet: 2.465 ± 0.041	3.525GluAsn: 3.525 ± 0.054	2.161GluPro: 2.161 ± 0.044	3.164GluGln: 3.164 ± 0.061	3.632GluArg: 3.632 ± 0.052	3.905GluSer: 3.905 ± 0.064	3.747GluThr: 3.747 ± 0.057	4.708GluVal: 4.708 ± 0.06	0.869GluTrp: 0.869 ± 0.024	2.396GluTyr: 2.396 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	3.561PheAla: 3.561 ± 0.059	0.366PheCys: 0.366 ± 0.018	2.166PheAsp: 2.166 ± 0.038	2.811PheGlu: 2.811 ± 0.048	2.503PhePhe: 2.503 ± 0.051	3.417PheGly: 3.417 ± 0.062	0.976PheHis: 0.976 ± 0.029	3.752PheIle: 3.752 ± 0.054	2.382PheLys: 2.382 ± 0.041	4.859PheLeu: 4.859 ± 0.065	1.288PheMet: 1.288 ± 0.032	1.662PheAsn: 1.662 ± 0.038	1.813PhePro: 1.813 ± 0.037	1.569PheGln: 1.569 ± 0.029	1.845PheArg: 1.845 ± 0.041	3.542PheSer: 3.542 ± 0.059	2.534PheThr: 2.534 ± 0.046	2.712PheVal: 2.712 ± 0.051	0.527PheTrp: 0.527 ± 0.019	1.859PheTyr: 1.859 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	5.534GlyAla: 5.534 ± 0.078	0.656GlyCys: 0.656 ± 0.024	3.381GlyAsp: 3.381 ± 0.061	5.207GlyGlu: 5.207 ± 0.069	3.702GlyPhe: 3.702 ± 0.054	5.439GlyGly: 5.439 ± 0.078	1.383GlyHis: 1.383 ± 0.033	6.169GlyIle: 6.169 ± 0.063	5.453GlyLys: 5.453 ± 0.061	7.277GlyLeu: 7.277 ± 0.086	2.327GlyMet: 2.327 ± 0.041	2.705GlyAsn: 2.705 ± 0.048	1.987GlyPro: 1.987 ± 0.055	2.46GlyGln: 2.46 ± 0.045	3.47GlyArg: 3.47 ± 0.057	4.833GlySer: 4.833 ± 0.063	4.233GlyThr: 4.233 ± 0.063	4.63GlyVal: 4.63 ± 0.069	0.906GlyTrp: 0.906 ± 0.025	2.852GlyTyr: 2.852 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.299HisAla: 1.299 ± 0.031	0.194HisCys: 0.194 ± 0.013	0.951HisAsp: 0.951 ± 0.023	1.347HisGlu: 1.347 ± 0.033	1.042HisPhe: 1.042 ± 0.027	1.397HisGly: 1.397 ± 0.04	0.619HisHis: 0.619 ± 0.021	1.413HisIle: 1.413 ± 0.029	0.973HisLys: 0.973 ± 0.029	1.997HisLeu: 1.997 ± 0.042	0.495HisMet: 0.495 ± 0.02	0.686HisAsn: 0.686 ± 0.02	1.117HisPro: 1.117 ± 0.029	0.728HisGln: 0.728 ± 0.022	0.843HisArg: 0.843 ± 0.023	1.223HisSer: 1.223 ± 0.032	0.951HisThr: 0.951 ± 0.028	1.162HisVal: 1.162 ± 0.029	0.237HisTrp: 0.237 ± 0.015	0.851HisTyr: 0.851 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.929IleAla: 5.929 ± 0.069	0.62IleCys: 0.62 ± 0.022	3.785IleAsp: 3.785 ± 0.056	5.336IleGlu: 5.336 ± 0.068	3.276IlePhe: 3.276 ± 0.052	5.755IleGly: 5.755 ± 0.082	1.495IleHis: 1.495 ± 0.03	5.643IleIle: 5.643 ± 0.08	4.163IleLys: 4.163 ± 0.057	7.3IleLeu: 7.3 ± 0.093	1.89IleMet: 1.89 ± 0.037	2.717IleAsn: 2.717 ± 0.056	3.196IlePro: 3.196 ± 0.052	2.594IleGln: 2.594 ± 0.044	3.332IleArg: 3.332 ± 0.055	5.361IleSer: 5.361 ± 0.072	3.823IleThr: 3.823 ± 0.062	4.658IleVal: 4.658 ± 0.067	0.654IleTrp: 0.654 ± 0.025	2.411IleTyr: 2.411 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	5.232LysAla: 5.232 ± 0.084	0.273LysCys: 0.273 ± 0.014	3.851LysAsp: 3.851 ± 0.048	7.049LysGlu: 7.049 ± 0.082	1.758LysPhe: 1.758 ± 0.033	4.938LysGly: 4.938 ± 0.064	1.174LysHis: 1.174 ± 0.033	4.257LysIle: 4.257 ± 0.059	5.594LysLys: 5.594 ± 0.083	5.756LysLeu: 5.756 ± 0.072	2.089LysMet: 2.089 ± 0.038	2.939LysAsn: 2.939 ± 0.048	2.218LysPro: 2.218 ± 0.04	2.523LysGln: 2.523 ± 0.046	3.172LysArg: 3.172 ± 0.053	3.481LysSer: 3.481 ± 0.053	3.326LysThr: 3.326 ± 0.05	4.093LysVal: 4.093 ± 0.066	0.768LysTrp: 0.768 ± 0.025	1.973LysTyr: 1.973 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	8.754LeuAla: 8.754 ± 0.087	0.653LeuCys: 0.653 ± 0.026	4.929LeuAsp: 4.929 ± 0.065	7.234LeuGlu: 7.234 ± 0.09	5.048LeuPhe: 5.048 ± 0.074	6.705LeuGly: 6.705 ± 0.079	1.869LeuHis: 1.869 ± 0.04	6.997LeuIle: 6.997 ± 0.087	6.727LeuLys: 6.727 ± 0.075	10.843LeuLeu: 10.843 ± 0.127	2.62LeuMet: 2.62 ± 0.042	3.808LeuAsn: 3.808 ± 0.052	4.261LeuPro: 4.261 ± 0.067	3.496LeuGln: 3.496 ± 0.057	3.666LeuArg: 3.666 ± 0.058	7.103LeuSer: 7.103 ± 0.086	5.168LeuThr: 5.168 ± 0.073	5.745LeuVal: 5.745 ± 0.072	0.911LeuTrp: 0.911 ± 0.025	3.251LeuTyr: 3.251 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.463MetAla: 2.463 ± 0.046	0.124MetCys: 0.124 ± 0.009	1.568MetAsp: 1.568 ± 0.037	2.291MetGlu: 2.291 ± 0.046	1.008MetPhe: 1.008 ± 0.023	1.855MetGly: 1.855 ± 0.036	0.421MetHis: 0.421 ± 0.019	2.084MetIle: 2.084 ± 0.047	2.585MetLys: 2.585 ± 0.04	2.906MetLeu: 2.906 ± 0.047	0.894MetMet: 0.894 ± 0.028	1.434MetAsn: 1.434 ± 0.034	1.168MetPro: 1.168 ± 0.036	0.887MetGln: 0.887 ± 0.028	1.091MetArg: 1.091 ± 0.027	1.568MetSer: 1.568 ± 0.031	1.482MetThr: 1.482 ± 0.033	1.669MetVal: 1.669 ± 0.029	0.196MetTrp: 0.196 ± 0.012	0.689MetTyr: 0.689 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	2.633AsnAla: 2.633 ± 0.052	0.257AsnCys: 0.257 ± 0.014	1.865AsnAsp: 1.865 ± 0.039	3.134AsnGlu: 3.134 ± 0.053	1.408AsnPhe: 1.408 ± 0.034	3.223AsnGly: 3.223 ± 0.057	0.831AsnHis: 0.831 ± 0.026	2.94AsnIle: 2.94 ± 0.048	2.358AsnLys: 2.358 ± 0.042	3.489AsnLeu: 3.489 ± 0.053	1.067AsnMet: 1.067 ± 0.028	1.43AsnAsn: 1.43 ± 0.038	1.975AsnPro: 1.975 ± 0.044	1.432AsnGln: 1.432 ± 0.034	1.854AsnArg: 1.854 ± 0.041	2.281AsnSer: 2.281 ± 0.04	1.795AsnThr: 1.795 ± 0.038	2.314AsnVal: 2.314 ± 0.04	0.437AsnTrp: 0.437 ± 0.019	1.298AsnTyr: 1.298 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	3.353ProAla: 3.353 ± 0.052	0.207ProCys: 0.207 ± 0.014	2.295ProAsp: 2.295 ± 0.036	3.54ProGlu: 3.54 ± 0.057	2.154ProPhe: 2.154 ± 0.044	3.035ProGly: 3.035 ± 0.052	0.791ProHis: 0.791 ± 0.025	2.373ProIle: 2.373 ± 0.047	1.912ProLys: 1.912 ± 0.036	3.684ProLeu: 3.684 ± 0.06	0.818ProMet: 0.818 ± 0.025	1.275ProAsn: 1.275 ± 0.03	1.117ProPro: 1.117 ± 0.025	1.176ProGln: 1.176 ± 0.038	1.159ProArg: 1.159 ± 0.032	2.284ProSer: 2.284 ± 0.04	1.317ProThr: 1.317 ± 0.035	3.133ProVal: 3.133 ± 0.051	0.392ProTrp: 0.392 ± 0.018	1.45ProTyr: 1.45 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.897GlnAla: 2.897 ± 0.047	0.181GlnCys: 0.181 ± 0.012	1.657GlnAsp: 1.657 ± 0.034	2.884GlnGlu: 2.884 ± 0.05	1.471GlnPhe: 1.471 ± 0.033	2.23GlnGly: 2.23 ± 0.077	0.681GlnHis: 0.681 ± 0.024	2.278GlnIle: 2.278 ± 0.045	2.559GlnLys: 2.559 ± 0.045	3.606GlnLeu: 3.606 ± 0.067	1.092GlnMet: 1.092 ± 0.031	1.419GlnAsn: 1.419 ± 0.035	1.256GlnPro: 1.256 ± 0.037	1.517GlnGln: 1.517 ± 0.045	1.411GlnArg: 1.411 ± 0.033	2.009GlnSer: 2.009 ± 0.037	1.812GlnThr: 1.812 ± 0.03	1.979GlnVal: 1.979 ± 0.036	0.35GlnTrp: 0.35 ± 0.014	1.295GlnTyr: 1.295 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	2.706ArgAla: 2.706 ± 0.045	0.262ArgCys: 0.262 ± 0.012	2.12ArgAsp: 2.12 ± 0.039	3.728ArgGlu: 3.728 ± 0.062	2.042ArgPhe: 2.042 ± 0.043	2.495ArgGly: 2.495 ± 0.048	0.859ArgHis: 0.859 ± 0.023	3.248ArgIle: 3.248 ± 0.051	3.557ArgLys: 3.557 ± 0.054	4.504ArgLeu: 4.504 ± 0.065	1.402ArgMet: 1.402 ± 0.035	1.948ArgAsn: 1.948 ± 0.039	1.485ArgPro: 1.485 ± 0.034	1.729ArgGln: 1.729 ± 0.036	2.055ArgArg: 2.055 ± 0.044	2.467ArgSer: 2.467 ± 0.045	2.16ArgThr: 2.16 ± 0.042	2.491ArgVal: 2.491 ± 0.042	0.479ArgTrp: 0.479 ± 0.02	1.527ArgTyr: 1.527 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	4.892SerAla: 4.892 ± 0.067	0.5SerCys: 0.5 ± 0.022	2.811SerAsp: 2.811 ± 0.048	4.161SerGlu: 4.161 ± 0.063	3.613SerPhe: 3.613 ± 0.05	5.387SerGly: 5.387 ± 0.063	1.226SerHis: 1.226 ± 0.03	5.097SerIle: 5.097 ± 0.071	3.432SerLys: 3.432 ± 0.048	6.698SerLeu: 6.698 ± 0.071	1.94SerMet: 1.94 ± 0.037	2.007SerAsn: 2.007 ± 0.047	2.393SerPro: 2.393 ± 0.045	1.978SerGln: 1.978 ± 0.038	3.062SerArg: 3.062 ± 0.045	4.565SerSer: 4.565 ± 0.072	2.733SerThr: 2.733 ± 0.045	4.019SerVal: 4.019 ± 0.055	0.765SerTrp: 0.765 ± 0.025	2.292SerTyr: 2.292 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	4.49ThrAla: 4.49 ± 0.068	0.299ThrCys: 0.299 ± 0.015	2.565ThrAsp: 2.565 ± 0.047	3.484ThrGlu: 3.484 ± 0.059	2.271ThrPhe: 2.271 ± 0.036	4.529ThrGly: 4.529 ± 0.068	0.858ThrHis: 0.858 ± 0.025	3.654ThrIle: 3.654 ± 0.054	2.636ThrLys: 2.636 ± 0.042	4.582ThrLeu: 4.582 ± 0.055	1.219ThrMet: 1.219 ± 0.028	1.734ThrAsn: 1.734 ± 0.035	2.015ThrPro: 2.015 ± 0.042	1.143ThrGln: 1.143 ± 0.031	1.755ThrArg: 1.755 ± 0.039	2.808ThrSer: 2.808 ± 0.048	1.99ThrThr: 1.99 ± 0.043	3.983ThrVal: 3.983 ± 0.059	0.442ThrTrp: 0.442 ± 0.02	1.613ThrTyr: 1.613 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	4.208ValAla: 4.208 ± 0.067	0.597ValCys: 0.597 ± 0.023	3.011ValAsp: 3.011 ± 0.044	4.125ValGlu: 4.125 ± 0.055	3.203ValPhe: 3.203 ± 0.054	3.747ValGly: 3.747 ± 0.06	1.344ValHis: 1.344 ± 0.031	5.26ValIle: 5.26 ± 0.069	4.395ValLys: 4.395 ± 0.067	6.923ValLeu: 6.923 ± 0.075	1.799ValMet: 1.799 ± 0.035	2.694ValAsn: 2.694 ± 0.05	2.787ValPro: 2.787 ± 0.041	2.246ValGln: 2.246 ± 0.04	2.756ValArg: 2.756 ± 0.044	4.596ValSer: 4.596 ± 0.059	3.332ValThr: 3.332 ± 0.052	3.806ValVal: 3.806 ± 0.06	0.629ValTrp: 0.629 ± 0.023	2.209ValTyr: 2.209 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.705TrpAla: 0.705 ± 0.024	0.066TrpCys: 0.066 ± 0.007	0.556TrpAsp: 0.556 ± 0.021	0.731TrpGlu: 0.731 ± 0.024	0.52TrpPhe: 0.52 ± 0.019	0.74TrpGly: 0.74 ± 0.023	0.231TrpHis: 0.231 ± 0.013	0.778TrpIle: 0.778 ± 0.023	0.78TrpLys: 0.78 ± 0.025	1.208TrpLeu: 1.208 ± 0.03	0.36TrpMet: 0.36 ± 0.017	0.511TrpAsn: 0.511 ± 0.021	0.288TrpPro: 0.288 ± 0.013	0.403TrpGln: 0.403 ± 0.016	0.418TrpArg: 0.418 ± 0.018	0.606TrpSer: 0.606 ± 0.019	0.551TrpThr: 0.551 ± 0.023	0.568TrpVal: 0.568 ± 0.021	0.139TrpTrp: 0.139 ± 0.01	0.315TrpTyr: 0.315 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.187TyrAla: 2.187 ± 0.039	0.28TyrCys: 0.28 ± 0.014	1.791TyrAsp: 1.791 ± 0.04	2.495TyrGlu: 2.495 ± 0.046	1.909TyrPhe: 1.909 ± 0.041	2.527TyrGly: 2.527 ± 0.046	0.798TyrHis: 0.798 ± 0.024	2.503TyrIle: 2.503 ± 0.04	2.07TyrLys: 2.07 ± 0.042	3.44TyrLeu: 3.44 ± 0.051	0.939TyrMet: 0.939 ± 0.024	1.284TyrAsn: 1.284 ± 0.03	1.443TyrPro: 1.443 ± 0.034	1.353TyrGln: 1.353 ± 0.035	1.645TyrArg: 1.645 ± 0.038	2.341TyrSer: 2.341 ± 0.042	1.808TyrThr: 1.808 ± 0.038	1.899TyrVal: 1.899 ± 0.036	0.392TyrTrp: 0.392 ± 0.02	1.411TyrTyr: 1.411 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5066 proteins (1383718 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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