Amino acid dipepetide frequency for Scleropages formosus (Asian bonytongue) (Osteoglossum formosum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.504AlaAla: 6.504 ± 0.039	1.45AlaCys: 1.45 ± 0.012	3.211AlaAsp: 3.211 ± 0.017	4.906AlaGlu: 4.906 ± 0.031	2.516AlaPhe: 2.516 ± 0.016	4.719AlaGly: 4.719 ± 0.027	1.651AlaHis: 1.651 ± 0.012	2.735AlaIle: 2.735 ± 0.015	3.375AlaLys: 3.375 ± 0.02	7.102AlaLeu: 7.102 ± 0.033	1.689AlaMet: 1.689 ± 0.012	2.052AlaAsn: 2.052 ± 0.015	3.858AlaPro: 3.858 ± 0.029	3.079AlaGln: 3.079 ± 0.019	3.751AlaArg: 3.751 ± 0.023	5.676AlaSer: 5.676 ± 0.03	3.556AlaThr: 3.556 ± 0.019	5.311AlaVal: 5.311 ± 0.026	0.746AlaTrp: 0.746 ± 0.008	1.514AlaTyr: 1.514 ± 0.01	0.017AlaXaa: 0.017 ± 0.001
Cys	1.422CysAla: 1.422 ± 0.013	0.701CysCys: 0.701 ± 0.01	1.128CysAsp: 1.128 ± 0.014	1.311CysGlu: 1.311 ± 0.014	0.914CysPhe: 0.914 ± 0.01	1.642CysGly: 1.642 ± 0.018	0.692CysHis: 0.692 ± 0.009	0.946CysIle: 0.946 ± 0.012	1.124CysLys: 1.124 ± 0.012	2.235CysLeu: 2.235 ± 0.018	0.475CysMet: 0.475 ± 0.007	0.816CysAsn: 0.816 ± 0.01	1.472CysPro: 1.472 ± 0.02	1.053CysGln: 1.053 ± 0.014	1.495CysArg: 1.495 ± 0.014	2.218CysSer: 2.218 ± 0.021	1.247CysThr: 1.247 ± 0.011	1.579CysVal: 1.579 ± 0.015	0.332CysTrp: 0.332 ± 0.007	0.63CysTyr: 0.63 ± 0.008	0.004CysXaa: 0.004 ± 0.001
Asp	3.024AspAla: 3.024 ± 0.017	1.157AspCys: 1.157 ± 0.015	2.729AspAsp: 2.729 ± 0.023	3.508AspGlu: 3.508 ± 0.024	2.054AspPhe: 2.054 ± 0.013	3.666AspGly: 3.666 ± 0.022	1.165AspHis: 1.165 ± 0.01	2.54AspIle: 2.54 ± 0.02	2.502AspLys: 2.502 ± 0.019	4.892AspLeu: 4.892 ± 0.021	1.259AspMet: 1.259 ± 0.011	1.724AspAsn: 1.724 ± 0.016	2.942AspPro: 2.942 ± 0.016	1.769AspGln: 1.769 ± 0.015	2.825AspArg: 2.825 ± 0.019	4.321AspSer: 4.321 ± 0.024	2.612AspThr: 2.612 ± 0.016	3.298AspVal: 3.298 ± 0.017	0.668AspTrp: 0.668 ± 0.007	1.446AspTyr: 1.446 ± 0.012	0.005AspXaa: 0.005 ± 0.001
Glu	4.909GluAla: 4.909 ± 0.031	1.283GluCys: 1.283 ± 0.017	4.323GluAsp: 4.323 ± 0.023	7.351GluGlu: 7.351 ± 0.053	1.931GluPhe: 1.931 ± 0.016	4.366GluGly: 4.366 ± 0.021	1.528GluHis: 1.528 ± 0.012	2.72GluIle: 2.72 ± 0.021	4.594GluLys: 4.594 ± 0.032	6.234GluLeu: 6.234 ± 0.038	1.741GluMet: 1.741 ± 0.014	2.668GluAsn: 2.668 ± 0.02	2.967GluPro: 2.967 ± 0.023	3.143GluGln: 3.143 ± 0.026	4.46GluArg: 4.46 ± 0.031	4.352GluSer: 4.352 ± 0.024	3.234GluThr: 3.234 ± 0.022	4.382GluVal: 4.382 ± 0.021	0.704GluTrp: 0.704 ± 0.009	1.588GluTyr: 1.588 ± 0.017	0.009GluXaa: 0.009 ± 0.001
Phe	2.113PheAla: 2.113 ± 0.016	0.965PheCys: 0.965 ± 0.01	1.72PheAsp: 1.72 ± 0.011	1.904PheGlu: 1.904 ± 0.017	1.601PhePhe: 1.601 ± 0.015	2.268PheGly: 2.268 ± 0.018	1.051PheHis: 1.051 ± 0.01	1.73PheIle: 1.73 ± 0.016	1.644PheLys: 1.644 ± 0.012	3.954PheLeu: 3.954 ± 0.023	0.781PheMet: 0.781 ± 0.009	1.315PheAsn: 1.315 ± 0.011	1.935PhePro: 1.935 ± 0.014	1.659PheGln: 1.659 ± 0.012	2.063PheArg: 2.063 ± 0.02	3.41PheSer: 3.41 ± 0.019	2.124PheThr: 2.124 ± 0.015	2.329PheVal: 2.329 ± 0.018	0.488PheTrp: 0.488 ± 0.007	1.188PheTyr: 1.188 ± 0.012	0.004PheXaa: 0.004 ± 0.001
Gly	4.589GlyAla: 4.589 ± 0.025	1.384GlyCys: 1.384 ± 0.013	3.331GlyAsp: 3.331 ± 0.022	4.14GlyGlu: 4.14 ± 0.026	2.457GlyPhe: 2.457 ± 0.019	5.371GlyGly: 5.371 ± 0.041	1.789GlyHis: 1.789 ± 0.015	2.614GlyIle: 2.614 ± 0.014	3.554GlyLys: 3.554 ± 0.02	5.666GlyLeu: 5.666 ± 0.029	1.493GlyMet: 1.493 ± 0.012	2.4GlyAsn: 2.4 ± 0.018	3.574GlyPro: 3.574 ± 0.039	2.801GlyGln: 2.801 ± 0.022	4.021GlyArg: 4.021 ± 0.023	5.987GlySer: 5.987 ± 0.034	3.755GlyThr: 3.755 ± 0.023	4.194GlyVal: 4.194 ± 0.022	0.822GlyTrp: 0.822 ± 0.009	1.865GlyTyr: 1.865 ± 0.016	0.017GlyXaa: 0.017 ± 0.001
His	1.477HisAla: 1.477 ± 0.012	0.786HisCys: 0.786 ± 0.01	0.942HisAsp: 0.942 ± 0.009	1.262HisGlu: 1.262 ± 0.012	1.078HisPhe: 1.078 ± 0.011	1.691HisGly: 1.691 ± 0.013	0.929HisHis: 0.929 ± 0.013	1.228HisIle: 1.228 ± 0.01	1.234HisLys: 1.234 ± 0.011	2.766HisLeu: 2.766 ± 0.018	0.649HisMet: 0.649 ± 0.008	0.938HisAsn: 0.938 ± 0.01	1.642HisPro: 1.642 ± 0.014	1.162HisGln: 1.162 ± 0.01	1.717HisArg: 1.717 ± 0.014	2.379HisSer: 2.379 ± 0.016	1.457HisThr: 1.457 ± 0.014	1.602HisVal: 1.602 ± 0.012	0.358HisTrp: 0.358 ± 0.006	0.824HisTyr: 0.824 ± 0.01	0.004HisXaa: 0.004 ± 0.001
Ile	2.597IleAla: 2.597 ± 0.019	1.036IleCys: 1.036 ± 0.011	1.941IleAsp: 1.941 ± 0.015	2.266IleGlu: 2.266 ± 0.022	1.757IlePhe: 1.757 ± 0.016	2.206IleGly: 2.206 ± 0.016	1.142IleHis: 1.142 ± 0.01	2.185IleIle: 2.185 ± 0.018	2.276IleLys: 2.276 ± 0.02	4.135IleLeu: 4.135 ± 0.022	1.009IleMet: 1.009 ± 0.009	1.698IleAsn: 1.698 ± 0.013	2.433IlePro: 2.433 ± 0.014	2.029IleGln: 2.029 ± 0.017	2.344IleArg: 2.344 ± 0.015	3.529IleSer: 3.529 ± 0.02	2.545IleThr: 2.545 ± 0.026	2.596IleVal: 2.596 ± 0.02	0.463IleTrp: 0.463 ± 0.006	1.296IleTyr: 1.296 ± 0.011	0.004IleXaa: 0.004 ± 0.001
Lys	3.791LysAla: 3.791 ± 0.022	1.018LysCys: 1.018 ± 0.011	3.021LysAsp: 3.021 ± 0.024	4.634LysGlu: 4.634 ± 0.034	1.559LysPhe: 1.559 ± 0.013	3.268LysGly: 3.268 ± 0.023	1.315LysHis: 1.315 ± 0.012	2.293LysIle: 2.293 ± 0.02	4.136LysLys: 4.136 ± 0.033	4.746LysLeu: 4.746 ± 0.028	1.435LysMet: 1.435 ± 0.012	2.084LysAsn: 2.084 ± 0.016	2.707LysPro: 2.707 ± 0.022	2.399LysGln: 2.399 ± 0.02	3.33LysArg: 3.33 ± 0.019	3.565LysSer: 3.565 ± 0.022	2.804LysThr: 2.804 ± 0.017	3.542LysVal: 3.542 ± 0.022	0.578LysTrp: 0.578 ± 0.008	1.45LysTyr: 1.45 ± 0.015	0.007LysXaa: 0.007 ± 0.001
Leu	6.516LeuAla: 6.516 ± 0.031	2.374LeuCys: 2.374 ± 0.021	4.821LeuAsp: 4.821 ± 0.022	6.673LeuGlu: 6.673 ± 0.042	3.389LeuPhe: 3.389 ± 0.023	5.604LeuGly: 5.604 ± 0.029	2.75LeuHis: 2.75 ± 0.019	3.55LeuIle: 3.55 ± 0.02	5.354LeuLys: 5.354 ± 0.032	10.385LeuLeu: 10.385 ± 0.054	2.068LeuMet: 2.068 ± 0.016	3.384LeuAsn: 3.384 ± 0.021	5.626LeuPro: 5.626 ± 0.03	5.477LeuGln: 5.477 ± 0.035	6.123LeuArg: 6.123 ± 0.029	8.365LeuSer: 8.365 ± 0.034	4.985LeuThr: 4.985 ± 0.022	5.744LeuVal: 5.744 ± 0.03	1.143LeuTrp: 1.143 ± 0.011	2.622LeuTyr: 2.622 ± 0.018	0.017LeuXaa: 0.017 ± 0.001
Met	1.902MetAla: 1.902 ± 0.014	0.497MetCys: 0.497 ± 0.007	1.398MetAsp: 1.398 ± 0.012	2.0MetGlu: 2.0 ± 0.016	0.823MetPhe: 0.823 ± 0.009	1.476MetGly: 1.476 ± 0.013	0.494MetHis: 0.494 ± 0.007	0.842MetIle: 0.842 ± 0.009	1.411MetLys: 1.411 ± 0.011	2.071MetLeu: 2.071 ± 0.014	0.67MetMet: 0.67 ± 0.008	0.863MetAsn: 0.863 ± 0.01	1.118MetPro: 1.118 ± 0.01	1.014MetGln: 1.014 ± 0.01	1.253MetArg: 1.253 ± 0.011	1.802MetSer: 1.802 ± 0.014	1.208MetThr: 1.208 ± 0.011	1.579MetVal: 1.579 ± 0.011	0.276MetTrp: 0.276 ± 0.005	0.631MetTyr: 0.631 ± 0.009	0.003MetXaa: 0.003 ± 0.0
Asn	2.119AsnAla: 2.119 ± 0.015	0.839AsnCys: 0.839 ± 0.01	1.52AsnAsp: 1.52 ± 0.014	1.992AsnGlu: 1.992 ± 0.016	1.352AsnPhe: 1.352 ± 0.011	2.677AsnGly: 2.677 ± 0.021	0.881AsnHis: 0.881 ± 0.01	1.936AsnIle: 1.936 ± 0.017	1.99AsnLys: 1.99 ± 0.015	3.414AsnLeu: 3.414 ± 0.02	0.969AsnMet: 0.969 ± 0.008	1.464AsnAsn: 1.464 ± 0.015	2.146AsnPro: 2.146 ± 0.016	1.45AsnGln: 1.45 ± 0.012	1.924AsnArg: 1.924 ± 0.014	2.929AsnSer: 2.929 ± 0.02	1.972AsnThr: 1.972 ± 0.015	2.288AsnVal: 2.288 ± 0.018	0.432AsnTrp: 0.432 ± 0.007	1.052AsnTyr: 1.052 ± 0.011	0.005AsnXaa: 0.005 ± 0.001
Pro	4.37ProAla: 4.37 ± 0.024	1.269ProCys: 1.269 ± 0.017	2.777ProAsp: 2.777 ± 0.016	3.89ProGlu: 3.89 ± 0.023	1.921ProPhe: 1.921 ± 0.016	4.461ProGly: 4.461 ± 0.051	1.527ProHis: 1.527 ± 0.014	1.824ProIle: 1.824 ± 0.017	2.512ProLys: 2.512 ± 0.019	5.189ProLeu: 5.189 ± 0.03	1.074ProMet: 1.074 ± 0.01	1.753ProAsn: 1.753 ± 0.013	5.45ProPro: 5.45 ± 0.049	2.685ProGln: 2.685 ± 0.021	3.21ProArg: 3.21 ± 0.024	5.683ProSer: 5.683 ± 0.034	3.025ProThr: 3.025 ± 0.021	3.956ProVal: 3.956 ± 0.025	0.639ProTrp: 0.639 ± 0.008	1.421ProTyr: 1.421 ± 0.012	0.016ProXaa: 0.016 ± 0.001
Gln	3.291GlnAla: 3.291 ± 0.025	1.003GlnCys: 1.003 ± 0.013	2.278GlnAsp: 2.278 ± 0.015	3.588GlnGlu: 3.588 ± 0.025	1.344GlnPhe: 1.344 ± 0.013	2.912GlnGly: 2.912 ± 0.021	1.328GlnHis: 1.328 ± 0.013	1.736GlnIle: 1.736 ± 0.015	2.512GlnLys: 2.512 ± 0.02	4.538GlnLeu: 4.538 ± 0.03	1.098GlnMet: 1.098 ± 0.01	1.681GlnAsn: 1.681 ± 0.014	2.53GlnPro: 2.53 ± 0.022	3.025GlnGln: 3.025 ± 0.031	3.033GlnArg: 3.033 ± 0.022	3.264GlnSer: 3.264 ± 0.023	2.22GlnThr: 2.22 ± 0.018	2.932GlnVal: 2.932 ± 0.017	0.564GlnTrp: 0.564 ± 0.007	1.222GlnTyr: 1.222 ± 0.013	0.007GlnXaa: 0.007 ± 0.001
Arg	4.038ArgAla: 4.038 ± 0.019	1.474ArgCys: 1.474 ± 0.017	3.05ArgAsp: 3.05 ± 0.018	4.111ArgGlu: 4.111 ± 0.027	2.049ArgPhe: 2.049 ± 0.016	3.828ArgGly: 3.828 ± 0.027	1.665ArgHis: 1.665 ± 0.016	2.376ArgIle: 2.376 ± 0.017	3.621ArgLys: 3.621 ± 0.022	5.526ArgLeu: 5.526 ± 0.028	1.363ArgMet: 1.363 ± 0.012	2.141ArgAsn: 2.141 ± 0.015	3.168ArgPro: 3.168 ± 0.024	2.74ArgGln: 2.74 ± 0.018	4.87ArgArg: 4.87 ± 0.032	4.923ArgSer: 4.923 ± 0.034	3.077ArgThr: 3.077 ± 0.016	3.645ArgVal: 3.645 ± 0.022	0.764ArgTrp: 0.764 ± 0.01	1.627ArgTyr: 1.627 ± 0.012	0.016ArgXaa: 0.016 ± 0.001
Ser	5.931SerAla: 5.931 ± 0.028	2.081SerCys: 2.081 ± 0.017	4.051SerAsp: 4.051 ± 0.021	4.906SerGlu: 4.906 ± 0.024	3.073SerPhe: 3.073 ± 0.017	5.73SerGly: 5.73 ± 0.03	2.188SerHis: 2.188 ± 0.015	3.219SerIle: 3.219 ± 0.02	3.818SerLys: 3.818 ± 0.022	8.254SerLeu: 8.254 ± 0.032	1.79SerMet: 1.79 ± 0.012	2.717SerAsn: 2.717 ± 0.018	5.905SerPro: 5.905 ± 0.042	3.757SerGln: 3.757 ± 0.027	4.886SerArg: 4.886 ± 0.028	9.719SerSer: 9.719 ± 0.056	4.735SerThr: 4.735 ± 0.024	5.42SerVal: 5.42 ± 0.024	1.058SerTrp: 1.058 ± 0.012	2.127SerTyr: 2.127 ± 0.015	0.017SerXaa: 0.017 ± 0.001
Thr	4.083ThrAla: 4.083 ± 0.021	1.398ThrCys: 1.398 ± 0.018	2.65ThrAsp: 2.65 ± 0.018	3.514ThrGlu: 3.514 ± 0.02	2.116ThrPhe: 2.116 ± 0.015	3.716ThrGly: 3.716 ± 0.025	1.282ThrHis: 1.282 ± 0.012	2.233ThrIle: 2.233 ± 0.021	2.42ThrLys: 2.42 ± 0.02	5.343ThrLeu: 5.343 ± 0.023	1.24ThrMet: 1.24 ± 0.009	1.66ThrAsn: 1.66 ± 0.016	3.561ThrPro: 3.561 ± 0.026	2.21ThrGln: 2.21 ± 0.017	2.633ThrArg: 2.633 ± 0.017	4.514ThrSer: 4.514 ± 0.026	2.924ThrThr: 2.924 ± 0.022	4.196ThrVal: 4.196 ± 0.027	0.703ThrTrp: 0.703 ± 0.01	1.413ThrTyr: 1.413 ± 0.014	0.011ThrXaa: 0.011 ± 0.001
Val	4.51ValAla: 4.51 ± 0.021	1.707ValCys: 1.707 ± 0.012	3.204ValAsp: 3.204 ± 0.019	4.169ValGlu: 4.169 ± 0.023	2.655ValPhe: 2.655 ± 0.018	3.788ValGly: 3.788 ± 0.022	1.676ValHis: 1.676 ± 0.012	2.868ValIle: 2.868 ± 0.023	3.45ValLys: 3.45 ± 0.024	6.654ValLeu: 6.654 ± 0.034	1.53ValMet: 1.53 ± 0.013	2.348ValAsn: 2.348 ± 0.02	3.766ValPro: 3.766 ± 0.02	2.943ValGln: 2.943 ± 0.019	3.629ValArg: 3.629 ± 0.017	5.47ValSer: 5.47 ± 0.025	4.045ValThr: 4.045 ± 0.031	4.531ValVal: 4.531 ± 0.026	0.8ValTrp: 0.8 ± 0.01	1.795ValTyr: 1.795 ± 0.014	0.011ValXaa: 0.011 ± 0.001
Trp	0.768TrpAla: 0.768 ± 0.008	0.27TrpCys: 0.27 ± 0.005	0.673TrpAsp: 0.673 ± 0.009	0.782TrpGlu: 0.782 ± 0.009	0.469TrpPhe: 0.469 ± 0.007	0.716TrpGly: 0.716 ± 0.009	0.3TrpHis: 0.3 ± 0.005	0.518TrpIle: 0.518 ± 0.007	0.738TrpLys: 0.738 ± 0.009	1.213TrpLeu: 1.213 ± 0.012	0.338TrpMet: 0.338 ± 0.006	0.527TrpAsn: 0.527 ± 0.008	0.494TrpPro: 0.494 ± 0.007	0.518TrpGln: 0.518 ± 0.007	0.795TrpArg: 0.795 ± 0.008	0.965TrpSer: 0.965 ± 0.012	0.729TrpThr: 0.729 ± 0.01	0.766TrpVal: 0.766 ± 0.009	0.195TrpTrp: 0.195 ± 0.005	0.35TrpTyr: 0.35 ± 0.006	0.003TrpXaa: 0.003 ± 0.001
Tyr	1.447TyrAla: 1.447 ± 0.014	0.74TyrCys: 0.74 ± 0.01	1.332TyrAsp: 1.332 ± 0.012	1.57TyrGlu: 1.57 ± 0.014	1.185TyrPhe: 1.185 ± 0.012	1.7TyrGly: 1.7 ± 0.015	0.766TyrHis: 0.766 ± 0.009	1.389TyrIle: 1.389 ± 0.018	1.409TyrLys: 1.409 ± 0.015	2.636TyrLeu: 2.636 ± 0.016	0.659TyrMet: 0.659 ± 0.008	1.111TyrAsn: 1.111 ± 0.012	1.34TyrPro: 1.34 ± 0.013	1.188TyrGln: 1.188 ± 0.011	1.697TyrArg: 1.697 ± 0.014	2.296TyrSer: 2.296 ± 0.014	1.558TyrThr: 1.558 ± 0.014	1.648TyrVal: 1.648 ± 0.014	0.392TyrTrp: 0.392 ± 0.008	0.953TyrTyr: 0.953 ± 0.012	0.002TyrXaa: 0.002 ± 0.0
Xaa	0.016XaaAla: 0.016 ± 0.001	0.006XaaCys: 0.006 ± 0.001	0.007XaaAsp: 0.007 ± 0.001	0.011XaaGlu: 0.011 ± 0.001	0.005XaaPhe: 0.005 ± 0.001	0.016XaaGly: 0.016 ± 0.001	0.004XaaHis: 0.004 ± 0.001	0.005XaaIle: 0.005 ± 0.001	0.006XaaLys: 0.006 ± 0.001	0.017XaaLeu: 0.017 ± 0.001	0.003XaaMet: 0.003 ± 0.001	0.004XaaAsn: 0.004 ± 0.001	0.018XaaPro: 0.018 ± 0.001	0.007XaaGln: 0.007 ± 0.001	0.013XaaArg: 0.013 ± 0.001	0.016XaaSer: 0.016 ± 0.001	0.008XaaThr: 0.008 ± 0.001	0.011XaaVal: 0.011 ± 0.001	0.002XaaTrp: 0.002 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.633XaaXaa: 0.633 ± 0.033

Statistics based on 24200 proteins (11792707 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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