Amino acid dipepetide frequency for Adlercreutzia equolifaciens subsp. celatus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.342AlaAla: 18.342 ± 0.304	2.172AlaCys: 2.172 ± 0.067	7.577AlaAsp: 7.577 ± 0.117	8.734AlaGlu: 8.734 ± 0.136	4.71AlaPhe: 4.71 ± 0.089	9.977AlaGly: 9.977 ± 0.151	2.027AlaHis: 2.027 ± 0.048	5.716AlaIle: 5.716 ± 0.104	4.024AlaLys: 4.024 ± 0.089	12.519AlaLeu: 12.519 ± 0.169	3.331AlaMet: 3.331 ± 0.077	3.006AlaAsn: 3.006 ± 0.068	5.45AlaPro: 5.45 ± 0.115	3.496AlaGln: 3.496 ± 0.083	7.234AlaArg: 7.234 ± 0.129	6.834AlaSer: 6.834 ± 0.104	6.049AlaThr: 6.049 ± 0.095	9.608AlaVal: 9.608 ± 0.137	1.36AlaTrp: 1.36 ± 0.044	2.933AlaTyr: 2.933 ± 0.061	0.0AlaXaa: 0.0 ± 0.0
Cys	1.998CysAla: 1.998 ± 0.067	0.275CysCys: 0.275 ± 0.021	1.002CysAsp: 1.002 ± 0.042	0.998CysGlu: 0.998 ± 0.035	0.513CysPhe: 0.513 ± 0.028	1.734CysGly: 1.734 ± 0.05	0.34CysHis: 0.34 ± 0.029	0.752CysIle: 0.752 ± 0.035	0.477CysLys: 0.477 ± 0.029	1.425CysLeu: 1.425 ± 0.041	0.37CysMet: 0.37 ± 0.023	0.404CysAsn: 0.404 ± 0.023	0.899CysPro: 0.899 ± 0.048	0.376CysGln: 0.376 ± 0.025	0.836CysArg: 0.836 ± 0.04	0.827CysSer: 0.827 ± 0.037	0.839CysThr: 0.839 ± 0.038	1.265CysVal: 1.265 ± 0.047	0.216CysTrp: 0.216 ± 0.016	0.443CysTyr: 0.443 ± 0.028	0.0CysXaa: 0.0 ± 0.0
Asp	8.105AspAla: 8.105 ± 0.132	0.704AspCys: 0.704 ± 0.029	3.796AspAsp: 3.796 ± 0.085	5.235AspGlu: 5.235 ± 0.102	2.451AspPhe: 2.451 ± 0.06	5.45AspGly: 5.45 ± 0.103	0.99AspHis: 0.99 ± 0.039	3.226AspIle: 3.226 ± 0.062	1.826AspLys: 1.826 ± 0.057	5.16AspLeu: 5.16 ± 0.096	1.58AspMet: 1.58 ± 0.045	1.542AspAsn: 1.542 ± 0.054	3.005AspPro: 3.005 ± 0.078	1.253AspGln: 1.253 ± 0.046	3.196AspArg: 3.196 ± 0.072	2.662AspSer: 2.662 ± 0.061	2.868AspThr: 2.868 ± 0.069	4.593AspVal: 4.593 ± 0.092	0.729AspTrp: 0.729 ± 0.032	1.915AspTyr: 1.915 ± 0.053	0.0AspXaa: 0.0 ± 0.0
Glu	9.138GluAla: 9.138 ± 0.136	0.779GluCys: 0.779 ± 0.041	3.71GluAsp: 3.71 ± 0.079	5.392GluGlu: 5.392 ± 0.116	2.05GluPhe: 2.05 ± 0.051	6.024GluGly: 6.024 ± 0.098	1.279GluHis: 1.279 ± 0.044	3.106GluIle: 3.106 ± 0.074	3.05GluLys: 3.05 ± 0.069	6.213GluLeu: 6.213 ± 0.114	1.855GluMet: 1.855 ± 0.055	2.252GluAsn: 2.252 ± 0.06	2.721GluPro: 2.721 ± 0.062	2.233GluGln: 2.233 ± 0.049	5.002GluArg: 5.002 ± 0.109	3.139GluSer: 3.139 ± 0.072	3.467GluThr: 3.467 ± 0.071	5.181GluVal: 5.181 ± 0.079	0.69GluTrp: 0.69 ± 0.032	1.714GluTyr: 1.714 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	4.532PheAla: 4.532 ± 0.085	0.708PheCys: 0.708 ± 0.032	2.795PheAsp: 2.795 ± 0.07	2.358PheGlu: 2.358 ± 0.057	1.572PhePhe: 1.572 ± 0.049	3.655PheGly: 3.655 ± 0.083	0.599PheHis: 0.599 ± 0.034	1.812PheIle: 1.812 ± 0.05	1.11PheLys: 1.11 ± 0.034	3.301PheLeu: 3.301 ± 0.077	0.989PheMet: 0.989 ± 0.041	1.175PheAsn: 1.175 ± 0.038	1.478PhePro: 1.478 ± 0.047	0.913PheGln: 0.913 ± 0.04	1.723PheArg: 1.723 ± 0.049	2.39PheSer: 2.39 ± 0.058	2.093PheThr: 2.093 ± 0.059	3.066PheVal: 3.066 ± 0.068	0.478PheTrp: 0.478 ± 0.026	1.252PheTyr: 1.252 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	9.738GlyAla: 9.738 ± 0.152	1.754GlyCys: 1.754 ± 0.056	4.775GlyAsp: 4.775 ± 0.089	5.437GlyGlu: 5.437 ± 0.088	3.307GlyPhe: 3.307 ± 0.068	6.478GlyGly: 6.478 ± 0.126	1.458GlyHis: 1.458 ± 0.05	4.65GlyIle: 4.65 ± 0.085	3.366GlyLys: 3.366 ± 0.079	7.551GlyLeu: 7.551 ± 0.13	2.321GlyMet: 2.321 ± 0.056	2.494GlyAsn: 2.494 ± 0.075	2.428GlyPro: 2.428 ± 0.063	2.119GlyGln: 2.119 ± 0.061	5.157GlyArg: 5.157 ± 0.1	4.634GlySer: 4.634 ± 0.092	4.872GlyThr: 4.872 ± 0.089	6.627GlyVal: 6.627 ± 0.097	1.06GlyTrp: 1.06 ± 0.044	2.555GlyTyr: 2.555 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	1.702HisAla: 1.702 ± 0.049	0.357HisCys: 0.357 ± 0.023	1.119HisAsp: 1.119 ± 0.043	1.154HisGlu: 1.154 ± 0.043	0.645HisPhe: 0.645 ± 0.032	1.657HisGly: 1.657 ± 0.052	0.414HisHis: 0.414 ± 0.029	0.928HisIle: 0.928 ± 0.037	0.461HisLys: 0.461 ± 0.027	1.597HisLeu: 1.597 ± 0.053	0.45HisMet: 0.45 ± 0.023	0.475HisAsn: 0.475 ± 0.025	1.069HisPro: 1.069 ± 0.041	0.434HisGln: 0.434 ± 0.025	1.04HisArg: 1.04 ± 0.04	0.948HisSer: 0.948 ± 0.037	0.932HisThr: 0.932 ± 0.033	1.287HisVal: 1.287 ± 0.049	0.202HisTrp: 0.202 ± 0.016	0.558HisTyr: 0.558 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.538IleAla: 6.538 ± 0.104	0.847IleCys: 0.847 ± 0.043	3.667IleAsp: 3.667 ± 0.08	3.613IleGlu: 3.613 ± 0.084	1.569IlePhe: 1.569 ± 0.051	4.095IleGly: 4.095 ± 0.081	0.754IleHis: 0.754 ± 0.029	2.531IleIle: 2.531 ± 0.075	1.48IleLys: 1.48 ± 0.051	3.837IleLeu: 3.837 ± 0.086	1.301IleMet: 1.301 ± 0.048	1.468IleAsn: 1.468 ± 0.056	2.42IlePro: 2.42 ± 0.062	1.146IleGln: 1.146 ± 0.038	2.264IleArg: 2.264 ± 0.061	2.572IleSer: 2.572 ± 0.059	2.703IleThr: 2.703 ± 0.061	4.625IleVal: 4.625 ± 0.086	0.489IleTrp: 0.489 ± 0.029	1.245IleTyr: 1.245 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	3.873LysAla: 3.873 ± 0.095	0.482LysCys: 0.482 ± 0.028	1.969LysAsp: 1.969 ± 0.059	2.281LysGlu: 2.281 ± 0.059	0.99LysPhe: 0.99 ± 0.037	2.674LysGly: 2.674 ± 0.058	0.652LysHis: 0.652 ± 0.031	1.644LysIle: 1.644 ± 0.056	1.972LysLys: 1.972 ± 0.062	3.091LysLeu: 3.091 ± 0.071	1.009LysMet: 1.009 ± 0.042	1.191LysAsn: 1.191 ± 0.044	1.565LysPro: 1.565 ± 0.05	1.04LysGln: 1.04 ± 0.038	2.42LysArg: 2.42 ± 0.06	1.952LysSer: 1.952 ± 0.058	2.078LysThr: 2.078 ± 0.052	2.687LysVal: 2.687 ± 0.074	0.378LysTrp: 0.378 ± 0.027	0.904LysTyr: 0.904 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	12.634LeuAla: 12.634 ± 0.165	1.507LeuCys: 1.507 ± 0.053	5.27LeuAsp: 5.27 ± 0.092	5.507LeuGlu: 5.507 ± 0.088	3.755LeuPhe: 3.755 ± 0.085	7.587LeuGly: 7.587 ± 0.124	1.407LeuHis: 1.407 ± 0.046	4.383LeuIle: 4.383 ± 0.091	3.051LeuLys: 3.051 ± 0.074	8.751LeuLeu: 8.751 ± 0.169	2.576LeuMet: 2.576 ± 0.067	2.33LeuAsn: 2.33 ± 0.061	4.447LeuPro: 4.447 ± 0.075	2.135LeuGln: 2.135 ± 0.06	5.457LeuArg: 5.457 ± 0.106	5.999LeuSer: 5.999 ± 0.103	5.067LeuThr: 5.067 ± 0.085	7.875LeuVal: 7.875 ± 0.126	1.068LeuTrp: 1.068 ± 0.046	2.452LeuTyr: 2.452 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	3.41MetAla: 3.41 ± 0.066	0.328MetCys: 0.328 ± 0.024	1.459MetAsp: 1.459 ± 0.043	1.79MetGlu: 1.79 ± 0.047	0.864MetPhe: 0.864 ± 0.038	2.294MetGly: 2.294 ± 0.063	0.434MetHis: 0.434 ± 0.023	1.2MetIle: 1.2 ± 0.043	1.041MetLys: 1.041 ± 0.041	2.365MetLeu: 2.365 ± 0.061	0.655MetMet: 0.655 ± 0.033	0.983MetAsn: 0.983 ± 0.038	1.393MetPro: 1.393 ± 0.049	0.74MetGln: 0.74 ± 0.03	1.702MetArg: 1.702 ± 0.048	1.491MetSer: 1.491 ± 0.05	1.65MetThr: 1.65 ± 0.046	1.854MetVal: 1.854 ± 0.058	0.238MetTrp: 0.238 ± 0.016	0.578MetTyr: 0.578 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.214AsnAla: 3.214 ± 0.07	0.392AsnCys: 0.392 ± 0.024	1.645AsnAsp: 1.645 ± 0.053	1.884AsnGlu: 1.884 ± 0.051	1.018AsnPhe: 1.018 ± 0.041	2.366AsnGly: 2.366 ± 0.071	0.526AsnHis: 0.526 ± 0.025	1.418AsnIle: 1.418 ± 0.047	0.866AsnLys: 0.866 ± 0.036	2.657AsnLeu: 2.657 ± 0.062	0.773AsnMet: 0.773 ± 0.03	0.858AsnAsn: 0.858 ± 0.039	1.993AsnPro: 1.993 ± 0.059	0.836AsnGln: 0.836 ± 0.035	1.608AsnArg: 1.608 ± 0.054	1.348AsnSer: 1.348 ± 0.047	1.458AsnThr: 1.458 ± 0.052	2.18AsnVal: 2.18 ± 0.062	0.373AsnTrp: 0.373 ± 0.023	0.894AsnTyr: 0.894 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	5.651ProAla: 5.651 ± 0.105	0.586ProCys: 0.586 ± 0.03	3.074ProAsp: 3.074 ± 0.067	3.92ProGlu: 3.92 ± 0.087	1.998ProPhe: 1.998 ± 0.047	3.395ProGly: 3.395 ± 0.074	0.888ProHis: 0.888 ± 0.042	1.952ProIle: 1.952 ± 0.053	1.458ProLys: 1.458 ± 0.044	4.282ProLeu: 4.282 ± 0.074	1.056ProMet: 1.056 ± 0.048	1.15ProAsn: 1.15 ± 0.042	1.353ProPro: 1.353 ± 0.038	1.336ProGln: 1.336 ± 0.043	2.391ProArg: 2.391 ± 0.058	2.572ProSer: 2.572 ± 0.068	2.505ProThr: 2.505 ± 0.062	3.716ProVal: 3.716 ± 0.082	0.613ProTrp: 0.613 ± 0.03	1.386ProTyr: 1.386 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	3.169GlnAla: 3.169 ± 0.075	0.402GlnCys: 0.402 ± 0.029	1.178GlnAsp: 1.178 ± 0.036	1.738GlnGlu: 1.738 ± 0.054	0.989GlnPhe: 0.989 ± 0.038	2.049GlnGly: 2.049 ± 0.05	0.518GlnHis: 0.518 ± 0.027	1.457GlnIle: 1.457 ± 0.048	1.191GlnLys: 1.191 ± 0.042	2.479GlnLeu: 2.479 ± 0.06	0.834GlnMet: 0.834 ± 0.035	0.872GlnAsn: 0.872 ± 0.036	1.196GlnPro: 1.196 ± 0.05	1.045GlnGln: 1.045 ± 0.038	1.791GlnArg: 1.791 ± 0.057	1.366GlnSer: 1.366 ± 0.047	1.427GlnThr: 1.427 ± 0.046	1.968GlnVal: 1.968 ± 0.051	0.414GlnTrp: 0.414 ± 0.026	0.749GlnTyr: 0.749 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	7.078ArgAla: 7.078 ± 0.142	0.928ArgCys: 0.928 ± 0.039	3.55ArgAsp: 3.55 ± 0.079	4.731ArgGlu: 4.731 ± 0.106	2.316ArgPhe: 2.316 ± 0.061	4.197ArgGly: 4.197 ± 0.089	1.2ArgHis: 1.2 ± 0.042	3.155ArgIle: 3.155 ± 0.063	2.284ArgLys: 2.284 ± 0.058	5.316ArgLeu: 5.316 ± 0.103	1.611ArgMet: 1.611 ± 0.045	1.646ArgAsn: 1.646 ± 0.053	2.56ArgPro: 2.56 ± 0.059	1.747ArgGln: 1.747 ± 0.054	4.646ArgArg: 4.646 ± 0.105	2.97ArgSer: 2.97 ± 0.06	3.115ArgThr: 3.115 ± 0.075	4.04ArgVal: 4.04 ± 0.079	0.678ArgTrp: 0.678 ± 0.035	1.835ArgTyr: 1.835 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	6.041SerAla: 6.041 ± 0.107	0.863SerCys: 0.863 ± 0.033	3.072SerAsp: 3.072 ± 0.073	3.214SerGlu: 3.214 ± 0.074	2.395SerPhe: 2.395 ± 0.07	4.72SerGly: 4.72 ± 0.097	0.956SerHis: 0.956 ± 0.036	2.654SerIle: 2.654 ± 0.067	1.8SerLys: 1.8 ± 0.052	5.68SerLeu: 5.68 ± 0.101	1.552SerMet: 1.552 ± 0.044	1.403SerAsn: 1.403 ± 0.043	2.486SerPro: 2.486 ± 0.056	1.609SerGln: 1.609 ± 0.045	3.273SerArg: 3.273 ± 0.075	3.483SerSer: 3.483 ± 0.088	2.727SerThr: 2.727 ± 0.061	4.348SerVal: 4.348 ± 0.079	0.71SerTrp: 0.71 ± 0.035	1.677SerTyr: 1.677 ± 0.06	0.0SerXaa: 0.0 ± 0.0
Thr	5.782ThrAla: 5.782 ± 0.089	0.854ThrCys: 0.854 ± 0.04	3.261ThrAsp: 3.261 ± 0.074	3.256ThrGlu: 3.256 ± 0.071	2.123ThrPhe: 2.123 ± 0.048	4.911ThrGly: 4.911 ± 0.095	0.941ThrHis: 0.941 ± 0.034	2.79ThrIle: 2.79 ± 0.077	1.592ThrLys: 1.592 ± 0.051	5.099ThrLeu: 5.099 ± 0.084	1.289ThrMet: 1.289 ± 0.039	1.377ThrAsn: 1.377 ± 0.045	3.083ThrPro: 3.083 ± 0.066	1.275ThrGln: 1.275 ± 0.041	2.634ThrArg: 2.634 ± 0.054	2.905ThrSer: 2.905 ± 0.069	2.921ThrThr: 2.921 ± 0.076	4.707ThrVal: 4.707 ± 0.088	0.633ThrTrp: 0.633 ± 0.032	1.765ThrTyr: 1.765 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	9.991ValAla: 9.991 ± 0.157	1.417ValCys: 1.417 ± 0.047	4.571ValAsp: 4.571 ± 0.077	5.157ValGlu: 5.157 ± 0.093	3.104ValPhe: 3.104 ± 0.081	6.035ValGly: 6.035 ± 0.116	1.243ValHis: 1.243 ± 0.046	4.04ValIle: 4.04 ± 0.073	2.544ValLys: 2.544 ± 0.06	7.746ValLeu: 7.746 ± 0.114	1.964ValMet: 1.964 ± 0.053	2.387ValAsn: 2.387 ± 0.056	4.011ValPro: 4.011 ± 0.072	1.876ValGln: 1.876 ± 0.047	4.654ValArg: 4.654 ± 0.093	4.651ValSer: 4.651 ± 0.082	4.425ValThr: 4.425 ± 0.09	7.307ValVal: 7.307 ± 0.102	0.781ValTrp: 0.781 ± 0.032	2.059ValTyr: 2.059 ± 0.056	0.0ValXaa: 0.0 ± 0.0
Trp	1.133TrpAla: 1.133 ± 0.04	0.198TrpCys: 0.198 ± 0.018	0.733TrpAsp: 0.733 ± 0.035	0.721TrpGlu: 0.721 ± 0.034	0.473TrpPhe: 0.473 ± 0.024	1.02TrpGly: 1.02 ± 0.046	0.26TrpHis: 0.26 ± 0.022	0.604TrpIle: 0.604 ± 0.031	0.453TrpLys: 0.453 ± 0.022	1.247TrpLeu: 1.247 ± 0.045	0.344TrpMet: 0.344 ± 0.022	0.41TrpAsn: 0.41 ± 0.026	0.449TrpPro: 0.449 ± 0.029	0.358TrpGln: 0.358 ± 0.023	0.714TrpArg: 0.714 ± 0.035	0.555TrpSer: 0.555 ± 0.032	0.518TrpThr: 0.518 ± 0.031	0.912TrpVal: 0.912 ± 0.035	0.182TrpTrp: 0.182 ± 0.018	0.32TrpTyr: 0.32 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.031TyrAla: 3.031 ± 0.065	0.438TyrCys: 0.438 ± 0.027	2.061TyrAsp: 2.061 ± 0.055	1.872TyrGlu: 1.872 ± 0.046	1.155TyrPhe: 1.155 ± 0.051	2.46TyrGly: 2.46 ± 0.062	0.542TyrHis: 0.542 ± 0.03	1.15TyrIle: 1.15 ± 0.041	0.809TyrLys: 0.809 ± 0.031	2.942TyrLeu: 2.942 ± 0.058	0.607TyrMet: 0.607 ± 0.03	0.883TyrAsn: 0.883 ± 0.042	1.276TyrPro: 1.276 ± 0.044	0.864TyrGln: 0.864 ± 0.037	1.862TyrArg: 1.862 ± 0.05	1.369TyrSer: 1.369 ± 0.046	1.483TyrThr: 1.483 ± 0.045	2.119TyrVal: 2.119 ± 0.052	0.311TyrTrp: 0.311 ± 0.019	0.996TyrTyr: 0.996 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2195 proteins (753156 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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