Amino acid dipepetide frequency for Limnochorda pilosa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.017AlaAla: 17.017 ± 0.169	0.912AlaCys: 0.912 ± 0.038	4.823AlaAsp: 4.823 ± 0.069	7.467AlaGlu: 7.467 ± 0.082	4.123AlaPhe: 4.123 ± 0.063	13.084AlaGly: 13.084 ± 0.13	2.162AlaHis: 2.162 ± 0.044	4.109AlaIle: 4.109 ± 0.072	1.653AlaLys: 1.653 ± 0.045	14.444AlaLeu: 14.444 ± 0.133	2.57AlaMet: 2.57 ± 0.043	1.778AlaAsn: 1.778 ± 0.043	5.86AlaPro: 5.86 ± 0.081	3.762AlaGln: 3.762 ± 0.062	11.568AlaArg: 11.568 ± 0.139	6.233AlaSer: 6.233 ± 0.074	5.373AlaThr: 5.373 ± 0.069	10.655AlaVal: 10.655 ± 0.113	2.139AlaTrp: 2.139 ± 0.048	2.723AlaTyr: 2.723 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.516CysAla: 0.516 ± 0.024	0.055CysCys: 0.055 ± 0.008	0.304CysAsp: 0.304 ± 0.017	0.31CysGlu: 0.31 ± 0.017	0.18CysPhe: 0.18 ± 0.013	0.744CysGly: 0.744 ± 0.032	0.2CysHis: 0.2 ± 0.021	0.258CysIle: 0.258 ± 0.015	0.098CysLys: 0.098 ± 0.01	0.608CysLeu: 0.608 ± 0.025	0.119CysMet: 0.119 ± 0.012	0.126CysAsn: 0.126 ± 0.011	0.517CysPro: 0.517 ± 0.026	0.213CysGln: 0.213 ± 0.015	0.66CysArg: 0.66 ± 0.026	0.325CysSer: 0.325 ± 0.018	0.348CysThr: 0.348 ± 0.017	0.428CysVal: 0.428 ± 0.024	0.099CysTrp: 0.099 ± 0.01	0.142CysTyr: 0.142 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	5.188AspAla: 5.188 ± 0.067	0.24AspCys: 0.24 ± 0.014	2.143AspAsp: 2.143 ± 0.064	3.373AspGlu: 3.373 ± 0.06	1.327AspPhe: 1.327 ± 0.038	4.836AspGly: 4.836 ± 0.09	0.977AspHis: 0.977 ± 0.032	1.174AspIle: 1.174 ± 0.034	0.496AspLys: 0.496 ± 0.022	6.188AspLeu: 6.188 ± 0.071	0.618AspMet: 0.618 ± 0.024	0.526AspAsn: 0.526 ± 0.023	4.364AspPro: 4.364 ± 0.087	1.569AspGln: 1.569 ± 0.043	4.797AspArg: 4.797 ± 0.074	1.391AspSer: 1.391 ± 0.038	1.582AspThr: 1.582 ± 0.041	4.17AspVal: 4.17 ± 0.063	0.674AspTrp: 0.674 ± 0.026	0.916AspTyr: 0.916 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	10.193GluAla: 10.193 ± 0.108	0.24GluCys: 0.24 ± 0.016	2.582GluAsp: 2.582 ± 0.049	5.52GluGlu: 5.52 ± 0.078	1.318GluPhe: 1.318 ± 0.033	6.159GluGly: 6.159 ± 0.078	1.354GluHis: 1.354 ± 0.036	2.758GluIle: 2.758 ± 0.053	1.427GluLys: 1.427 ± 0.042	7.211GluLeu: 7.211 ± 0.094	1.463GluMet: 1.463 ± 0.038	1.118GluAsn: 1.118 ± 0.03	4.167GluPro: 4.167 ± 0.078	2.298GluGln: 2.298 ± 0.05	7.064GluArg: 7.064 ± 0.105	2.491GluSer: 2.491 ± 0.048	3.09GluThr: 3.09 ± 0.05	5.786GluVal: 5.786 ± 0.085	0.843GluTrp: 0.843 ± 0.033	1.237GluTyr: 1.237 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.235PheAla: 3.235 ± 0.057	0.215PheCys: 0.215 ± 0.015	1.789PheAsp: 1.789 ± 0.034	1.815PheGlu: 1.815 ± 0.038	1.331PhePhe: 1.331 ± 0.039	3.031PheGly: 3.031 ± 0.056	0.775PheHis: 0.775 ± 0.026	1.074PheIle: 1.074 ± 0.034	0.486PheLys: 0.486 ± 0.024	3.76PheLeu: 3.76 ± 0.077	0.603PheMet: 0.603 ± 0.021	0.696PheAsn: 0.696 ± 0.027	1.77PhePro: 1.77 ± 0.038	1.185PheGln: 1.185 ± 0.035	2.521PheArg: 2.521 ± 0.048	1.612PheSer: 1.612 ± 0.042	1.732PheThr: 1.732 ± 0.041	2.622PheVal: 2.622 ± 0.048	0.554PheTrp: 0.554 ± 0.024	0.834PheTyr: 0.834 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	10.659GlyAla: 10.659 ± 0.127	0.752GlyCys: 0.752 ± 0.031	4.051GlyAsp: 4.051 ± 0.074	5.98GlyGlu: 5.98 ± 0.081	3.255GlyPhe: 3.255 ± 0.056	8.443GlyGly: 8.443 ± 0.105	1.828GlyHis: 1.828 ± 0.039	3.95GlyIle: 3.95 ± 0.066	2.134GlyLys: 2.134 ± 0.054	11.105GlyLeu: 11.105 ± 0.123	2.16GlyMet: 2.16 ± 0.041	1.662GlyAsn: 1.662 ± 0.05	5.082GlyPro: 5.082 ± 0.076	3.006GlyGln: 3.006 ± 0.054	9.111GlyArg: 9.111 ± 0.108	5.331GlySer: 5.331 ± 0.088	4.942GlyThr: 4.942 ± 0.084	7.825GlyVal: 7.825 ± 0.091	1.874GlyTrp: 1.874 ± 0.046	2.445GlyTyr: 2.445 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.164HisAla: 2.164 ± 0.047	0.158HisCys: 0.158 ± 0.012	0.887HisAsp: 0.887 ± 0.029	1.084HisGlu: 1.084 ± 0.031	0.6HisPhe: 0.6 ± 0.022	1.887HisGly: 1.887 ± 0.041	0.512HisHis: 0.512 ± 0.026	0.497HisIle: 0.497 ± 0.019	0.261HisLys: 0.261 ± 0.016	2.65HisLeu: 2.65 ± 0.056	0.32HisMet: 0.32 ± 0.019	0.309HisAsn: 0.309 ± 0.018	1.825HisPro: 1.825 ± 0.04	0.706HisGln: 0.706 ± 0.025	2.028HisArg: 2.028 ± 0.049	0.744HisSer: 0.744 ± 0.028	0.852HisThr: 0.852 ± 0.027	1.712HisVal: 1.712 ± 0.039	0.3HisTrp: 0.3 ± 0.015	0.45HisTyr: 0.45 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	3.831IleAla: 3.831 ± 0.07	0.27IleCys: 0.27 ± 0.016	1.946IleAsp: 1.946 ± 0.045	2.212IleGlu: 2.212 ± 0.054	1.091IlePhe: 1.091 ± 0.035	3.155IleGly: 3.155 ± 0.062	0.876IleHis: 0.876 ± 0.032	1.106IleIle: 1.106 ± 0.037	0.578IleLys: 0.578 ± 0.024	4.469IleLeu: 4.469 ± 0.069	0.595IleMet: 0.595 ± 0.025	0.679IleAsn: 0.679 ± 0.028	2.366IlePro: 2.366 ± 0.051	1.177IleGln: 1.177 ± 0.029	3.128IleArg: 3.128 ± 0.055	1.652IleSer: 1.652 ± 0.038	1.854IleThr: 1.854 ± 0.04	2.776IleVal: 2.776 ± 0.052	0.449IleTrp: 0.449 ± 0.018	0.827IleTyr: 0.827 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.172LysAla: 2.172 ± 0.056	0.091LysCys: 0.091 ± 0.01	0.876LysAsp: 0.876 ± 0.034	1.452LysGlu: 1.452 ± 0.039	0.3LysPhe: 0.3 ± 0.018	1.779LysGly: 1.779 ± 0.038	0.325LysHis: 0.325 ± 0.018	0.628LysIle: 0.628 ± 0.026	0.45LysLys: 0.45 ± 0.023	1.716LysLeu: 1.716 ± 0.042	0.33LysMet: 0.33 ± 0.017	0.386LysAsn: 0.386 ± 0.018	1.069LysPro: 1.069 ± 0.031	0.557LysGln: 0.557 ± 0.023	1.396LysArg: 1.396 ± 0.038	0.789LysSer: 0.789 ± 0.026	0.968LysThr: 0.968 ± 0.032	1.67LysVal: 1.67 ± 0.043	0.186LysTrp: 0.186 ± 0.014	0.356LysTyr: 0.356 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	16.079LeuAla: 16.079 ± 0.142	0.673LeuCys: 0.673 ± 0.029	5.893LeuAsp: 5.893 ± 0.078	8.573LeuGlu: 8.573 ± 0.107	3.904LeuPhe: 3.904 ± 0.071	10.727LeuGly: 10.727 ± 0.131	2.169LeuHis: 2.169 ± 0.055	3.653LeuIle: 3.653 ± 0.06	2.204LeuLys: 2.204 ± 0.051	13.091LeuLeu: 13.091 ± 0.169	2.055LeuMet: 2.055 ± 0.048	1.969LeuAsn: 1.969 ± 0.039	6.584LeuPro: 6.584 ± 0.077	3.704LeuGln: 3.704 ± 0.061	9.385LeuArg: 9.385 ± 0.099	5.87LeuSer: 5.87 ± 0.074	5.282LeuThr: 5.282 ± 0.077	10.162LeuVal: 10.162 ± 0.123	1.615LeuTrp: 1.615 ± 0.044	2.337LeuTyr: 2.337 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.664MetAla: 2.664 ± 0.055	0.07MetCys: 0.07 ± 0.009	1.012MetAsp: 1.012 ± 0.027	1.458MetGlu: 1.458 ± 0.034	0.372MetPhe: 0.372 ± 0.018	2.04MetGly: 2.04 ± 0.047	0.341MetHis: 0.341 ± 0.015	0.82MetIle: 0.82 ± 0.03	0.528MetLys: 0.528 ± 0.02	1.908MetLeu: 1.908 ± 0.041	0.437MetMet: 0.437 ± 0.022	0.444MetAsn: 0.444 ± 0.02	1.076MetPro: 1.076 ± 0.031	0.603MetGln: 0.603 ± 0.023	1.566MetArg: 1.566 ± 0.034	1.006MetSer: 1.006 ± 0.03	1.105MetThr: 1.105 ± 0.033	1.791MetVal: 1.791 ± 0.043	0.191MetTrp: 0.191 ± 0.015	0.271MetTyr: 0.271 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	1.876AsnAla: 1.876 ± 0.045	0.108AsnCys: 0.108 ± 0.011	0.772AsnAsp: 0.772 ± 0.029	0.873AsnGlu: 0.873 ± 0.026	0.479AsnPhe: 0.479 ± 0.025	1.612AsnGly: 1.612 ± 0.041	0.359AsnHis: 0.359 ± 0.02	0.511AsnIle: 0.511 ± 0.024	0.282AsnLys: 0.282 ± 0.019	2.382AsnLeu: 2.382 ± 0.048	0.259AsnMet: 0.259 ± 0.016	0.354AsnAsn: 0.354 ± 0.02	1.591AsnPro: 1.591 ± 0.04	0.574AsnGln: 0.574 ± 0.022	1.539AsnArg: 1.539 ± 0.038	0.577AsnSer: 0.577 ± 0.024	0.796AsnThr: 0.796 ± 0.029	1.577AsnVal: 1.577 ± 0.038	0.276AsnTrp: 0.276 ± 0.016	0.43AsnTyr: 0.43 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	7.295ProAla: 7.295 ± 0.089	0.279ProCys: 0.279 ± 0.016	3.65ProAsp: 3.65 ± 0.065	5.191ProGlu: 5.191 ± 0.075	1.938ProPhe: 1.938 ± 0.042	6.989ProGly: 6.989 ± 0.103	1.176ProHis: 1.176 ± 0.034	1.83ProIle: 1.83 ± 0.043	0.863ProLys: 0.863 ± 0.027	5.824ProLeu: 5.824 ± 0.087	1.179ProMet: 1.179 ± 0.035	1.041ProAsn: 1.041 ± 0.035	3.76ProPro: 3.76 ± 0.072	1.819ProGln: 1.819 ± 0.04	4.137ProArg: 4.137 ± 0.07	3.109ProSer: 3.109 ± 0.052	2.54ProThr: 2.54 ± 0.049	5.47ProVal: 5.47 ± 0.067	1.056ProTrp: 1.056 ± 0.03	1.42ProTyr: 1.42 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	4.939GlnAla: 4.939 ± 0.073	0.136GlnCys: 0.136 ± 0.012	1.347GlnAsp: 1.347 ± 0.035	2.71GlnGlu: 2.71 ± 0.057	0.68GlnPhe: 0.68 ± 0.026	3.112GlnGly: 3.112 ± 0.059	0.526GlnHis: 0.526 ± 0.023	1.24GlnIle: 1.24 ± 0.032	0.681GlnLys: 0.681 ± 0.03	2.834GlnLeu: 2.834 ± 0.052	0.719GlnMet: 0.719 ± 0.026	0.541GlnAsn: 0.541 ± 0.022	1.791GlnPro: 1.791 ± 0.038	1.177GlnGln: 1.177 ± 0.038	2.761GlnArg: 2.761 ± 0.055	1.131GlnSer: 1.131 ± 0.032	1.297GlnThr: 1.297 ± 0.033	3.828GlnVal: 3.828 ± 0.065	0.391GlnTrp: 0.391 ± 0.019	0.575GlnTyr: 0.575 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	9.628ArgAla: 9.628 ± 0.107	0.602ArgCys: 0.602 ± 0.028	3.53ArgAsp: 3.53 ± 0.056	6.397ArgGlu: 6.397 ± 0.091	3.388ArgPhe: 3.388 ± 0.058	6.645ArgGly: 6.645 ± 0.087	1.76ArgHis: 1.76 ± 0.04	3.671ArgIle: 3.671 ± 0.069	1.673ArgLys: 1.673 ± 0.039	11.145ArgLeu: 11.145 ± 0.118	2.134ArgMet: 2.134 ± 0.045	1.474ArgAsn: 1.474 ± 0.039	5.329ArgPro: 5.329 ± 0.08	3.02ArgGln: 3.02 ± 0.056	9.081ArgArg: 9.081 ± 0.121	4.471ArgSer: 4.471 ± 0.078	3.911ArgThr: 3.911 ± 0.055	7.825ArgVal: 7.825 ± 0.097	1.677ArgTrp: 1.677 ± 0.042	2.266ArgTyr: 2.266 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	4.712SerAla: 4.712 ± 0.067	0.342SerCys: 0.342 ± 0.019	2.239SerAsp: 2.239 ± 0.051	2.659SerGlu: 2.659 ± 0.049	1.891SerPhe: 1.891 ± 0.042	5.092SerGly: 5.092 ± 0.065	0.935SerHis: 0.935 ± 0.032	1.788SerIle: 1.788 ± 0.038	0.761SerLys: 0.761 ± 0.025	5.946SerLeu: 5.946 ± 0.083	1.103SerMet: 1.103 ± 0.034	0.775SerAsn: 0.775 ± 0.028	3.138SerPro: 3.138 ± 0.058	1.543SerGln: 1.543 ± 0.036	4.051SerArg: 4.051 ± 0.068	2.517SerSer: 2.517 ± 0.056	2.311SerThr: 2.311 ± 0.048	3.726SerVal: 3.726 ± 0.063	0.784SerTrp: 0.784 ± 0.03	1.185SerTyr: 1.185 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.312ThrAla: 5.312 ± 0.066	0.342ThrCys: 0.342 ± 0.02	2.122ThrAsp: 2.122 ± 0.05	2.403ThrGlu: 2.403 ± 0.05	1.764ThrPhe: 1.764 ± 0.046	5.166ThrGly: 5.166 ± 0.064	0.953ThrHis: 0.953 ± 0.033	1.486ThrIle: 1.486 ± 0.043	0.689ThrLys: 0.689 ± 0.027	5.817ThrLeu: 5.817 ± 0.068	0.751ThrMet: 0.751 ± 0.025	0.799ThrAsn: 0.799 ± 0.03	3.132ThrPro: 3.132 ± 0.057	1.28ThrGln: 1.28 ± 0.037	3.59ThrArg: 3.59 ± 0.055	2.364ThrSer: 2.364 ± 0.05	2.364ThrThr: 2.364 ± 0.053	4.502ThrVal: 4.502 ± 0.073	0.8ThrTrp: 0.8 ± 0.03	1.324ThrTyr: 1.324 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	11.035ValAla: 11.035 ± 0.108	0.495ValCys: 0.495 ± 0.022	4.6ValAsp: 4.6 ± 0.071	6.642ValGlu: 6.642 ± 0.084	2.536ValPhe: 2.536 ± 0.044	7.536ValGly: 7.536 ± 0.096	1.798ValHis: 1.798 ± 0.046	3.173ValIle: 3.173 ± 0.06	1.565ValLys: 1.565 ± 0.042	10.077ValLeu: 10.077 ± 0.109	1.584ValMet: 1.584 ± 0.039	1.72ValAsn: 1.72 ± 0.041	5.023ValPro: 5.023 ± 0.066	2.715ValGln: 2.715 ± 0.048	7.611ValArg: 7.611 ± 0.085	4.16ValSer: 4.16 ± 0.055	4.593ValThr: 4.593 ± 0.064	8.587ValVal: 8.587 ± 0.095	1.201ValTrp: 1.201 ± 0.032	1.858ValTyr: 1.858 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.683TrpAla: 1.683 ± 0.042	0.106TrpCys: 0.106 ± 0.01	0.691TrpAsp: 0.691 ± 0.028	0.971TrpGlu: 0.971 ± 0.028	0.408TrpPhe: 0.408 ± 0.019	1.313TrpGly: 1.313 ± 0.034	0.317TrpHis: 0.317 ± 0.019	0.756TrpIle: 0.756 ± 0.029	0.348TrpLys: 0.348 ± 0.016	1.923TrpLeu: 1.923 ± 0.049	0.387TrpMet: 0.387 ± 0.018	0.407TrpAsn: 0.407 ± 0.02	0.781TrpPro: 0.781 ± 0.03	0.639TrpGln: 0.639 ± 0.024	1.307TrpArg: 1.307 ± 0.036	0.847TrpSer: 0.847 ± 0.03	0.867TrpThr: 0.867 ± 0.03	1.388TrpVal: 1.388 ± 0.036	0.268TrpTrp: 0.268 ± 0.015	0.33TrpTyr: 0.33 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.256TyrAla: 2.256 ± 0.046	0.165TyrCys: 0.165 ± 0.011	1.292TyrAsp: 1.292 ± 0.063	1.23TyrGlu: 1.23 ± 0.036	0.756TyrPhe: 0.756 ± 0.029	2.243TyrGly: 2.243 ± 0.049	0.603TyrHis: 0.603 ± 0.027	0.557TyrIle: 0.557 ± 0.025	0.318TyrLys: 0.318 ± 0.018	2.833TyrLeu: 2.833 ± 0.054	0.318TyrMet: 0.318 ± 0.017	0.424TyrAsn: 0.424 ± 0.019	1.342TyrPro: 1.342 ± 0.039	0.87TyrGln: 0.87 ± 0.031	2.325TyrArg: 2.325 ± 0.053	0.876TyrSer: 0.876 ± 0.029	1.152TyrThr: 1.152 ± 0.035	2.01TyrVal: 2.01 ± 0.047	0.361TyrTrp: 0.361 ± 0.016	0.623TyrTyr: 0.623 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3599 proteins (1121070 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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