Amino acid dipepetide frequency for Tritrichomonas foetus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.389AlaAla: 3.389 ± 0.025	0.723AlaCys: 0.723 ± 0.008	2.381AlaAsp: 2.381 ± 0.017	3.006AlaGlu: 3.006 ± 0.019	2.674AlaPhe: 2.674 ± 0.016	1.782AlaGly: 1.782 ± 0.015	0.945AlaHis: 0.945 ± 0.009	4.061AlaIle: 4.061 ± 0.019	3.497AlaLys: 3.497 ± 0.02	4.747AlaLeu: 4.747 ± 0.025	1.173AlaMet: 1.173 ± 0.01	2.789AlaAsn: 2.789 ± 0.016	1.95AlaPro: 1.95 ± 0.015	2.129AlaGln: 2.129 ± 0.017	1.891AlaArg: 1.891 ± 0.015	3.81AlaSer: 3.81 ± 0.025	2.587AlaThr: 2.587 ± 0.017	2.651AlaVal: 2.651 ± 0.018	0.299AlaTrp: 0.299 ± 0.005	1.438AlaTyr: 1.438 ± 0.011	0.007AlaXaa: 0.007 ± 0.001
Cys	0.753CysAla: 0.753 ± 0.009	0.376CysCys: 0.376 ± 0.006	0.943CysAsp: 0.943 ± 0.009	1.005CysGlu: 1.005 ± 0.01	1.028CysPhe: 1.028 ± 0.01	0.881CysGly: 0.881 ± 0.009	0.411CysHis: 0.411 ± 0.006	1.209CysIle: 1.209 ± 0.011	0.915CysLys: 0.915 ± 0.011	1.473CysLeu: 1.473 ± 0.012	0.31CysMet: 0.31 ± 0.005	0.835CysAsn: 0.835 ± 0.009	0.643CysPro: 0.643 ± 0.008	0.702CysGln: 0.702 ± 0.009	0.621CysArg: 0.621 ± 0.007	1.253CysSer: 1.253 ± 0.012	0.705CysThr: 0.705 ± 0.011	0.857CysVal: 0.857 ± 0.009	0.152CysTrp: 0.152 ± 0.004	0.593CysTyr: 0.593 ± 0.008	0.003CysXaa: 0.003 ± 0.001
Asp	2.452AspAla: 2.452 ± 0.014	0.771AspCys: 0.771 ± 0.008	4.166AspAsp: 4.166 ± 0.03	4.655AspGlu: 4.655 ± 0.025	3.652AspPhe: 3.652 ± 0.019	2.217AspGly: 2.217 ± 0.017	1.077AspHis: 1.077 ± 0.009	4.605AspIle: 4.605 ± 0.025	3.409AspLys: 3.409 ± 0.023	5.162AspLeu: 5.162 ± 0.022	1.067AspMet: 1.067 ± 0.009	3.317AspAsn: 3.317 ± 0.016	2.293AspPro: 2.293 ± 0.017	2.307AspGln: 2.307 ± 0.014	1.82AspArg: 1.82 ± 0.014	4.514AspSer: 4.514 ± 0.022	2.35AspThr: 2.35 ± 0.012	2.876AspVal: 2.876 ± 0.014	0.432AspTrp: 0.432 ± 0.005	2.025AspTyr: 2.025 ± 0.014	0.01AspXaa: 0.01 ± 0.001
Glu	3.205GluAla: 3.205 ± 0.019	0.886GluCys: 0.886 ± 0.011	3.383GluAsp: 3.383 ± 0.02	6.195GluGlu: 6.195 ± 0.058	3.347GluPhe: 3.347 ± 0.017	2.007GluGly: 2.007 ± 0.017	1.083GluHis: 1.083 ± 0.012	6.564GluIle: 6.564 ± 0.031	6.46GluLys: 6.46 ± 0.043	6.049GluLeu: 6.049 ± 0.034	1.888GluMet: 1.888 ± 0.013	6.086GluAsn: 6.086 ± 0.035	1.886GluPro: 1.886 ± 0.016	2.65GluGln: 2.65 ± 0.02	2.539GluArg: 2.539 ± 0.017	4.986GluSer: 4.986 ± 0.026	3.569GluThr: 3.569 ± 0.021	2.966GluVal: 2.966 ± 0.018	0.506GluTrp: 0.506 ± 0.007	2.38GluTyr: 2.38 ± 0.017	0.011GluXaa: 0.011 ± 0.001
Phe	2.739PheAla: 2.739 ± 0.017	1.04PheCys: 1.04 ± 0.01	3.758PheAsp: 3.758 ± 0.019	3.573PheGlu: 3.573 ± 0.021	4.107PhePhe: 4.107 ± 0.211	2.49PheGly: 2.49 ± 0.018	1.353PheHis: 1.353 ± 0.01	4.552PheIle: 4.552 ± 0.029	3.016PheLys: 3.016 ± 0.016	5.523PheLeu: 5.523 ± 0.03	1.178PheMet: 1.178 ± 0.01	3.484PheAsn: 3.484 ± 0.018	2.324PhePro: 2.324 ± 0.016	2.244PheGln: 2.244 ± 0.015	1.868PheArg: 1.868 ± 0.014	5.187PheSer: 5.187 ± 0.03	3.031PheThr: 3.031 ± 0.021	3.065PheVal: 3.065 ± 0.019	0.47PheTrp: 0.47 ± 0.007	2.213PheTyr: 2.213 ± 0.016	0.009PheXaa: 0.009 ± 0.001
Gly	1.791GlyAla: 1.791 ± 0.017	0.683GlyCys: 0.683 ± 0.01	2.055GlyAsp: 2.055 ± 0.013	2.251GlyGlu: 2.251 ± 0.017	2.126GlyPhe: 2.126 ± 0.016	1.972GlyGly: 1.972 ± 0.025	0.805GlyHis: 0.805 ± 0.008	3.079GlyIle: 3.079 ± 0.018	2.817GlyLys: 2.817 ± 0.019	2.871GlyLeu: 2.871 ± 0.018	0.799GlyMet: 0.799 ± 0.009	2.629GlyAsn: 2.629 ± 0.018	1.155GlyPro: 1.155 ± 0.013	1.413GlyGln: 1.413 ± 0.01	1.502GlyArg: 1.502 ± 0.014	2.95GlySer: 2.95 ± 0.021	1.957GlyThr: 1.957 ± 0.015	2.027GlyVal: 2.027 ± 0.015	0.309GlyTrp: 0.309 ± 0.005	1.345GlyTyr: 1.345 ± 0.012	0.009GlyXaa: 0.009 ± 0.001
His	0.9HisAla: 0.9 ± 0.008	0.383HisCys: 0.383 ± 0.005	1.126HisAsp: 1.126 ± 0.009	1.385HisGlu: 1.385 ± 0.011	1.465HisPhe: 1.465 ± 0.011	0.815HisGly: 0.815 ± 0.008	0.701HisHis: 0.701 ± 0.011	1.67HisIle: 1.67 ± 0.013	1.354HisLys: 1.354 ± 0.01	2.073HisLeu: 2.073 ± 0.014	0.4HisMet: 0.4 ± 0.006	1.27HisAsn: 1.27 ± 0.011	1.073HisPro: 1.073 ± 0.01	1.156HisGln: 1.156 ± 0.01	0.963HisArg: 0.963 ± 0.009	1.877HisSer: 1.877 ± 0.014	0.917HisThr: 0.917 ± 0.009	0.999HisVal: 0.999 ± 0.009	0.188HisTrp: 0.188 ± 0.004	0.825HisTyr: 0.825 ± 0.008	0.003HisXaa: 0.003 ± 0.001
Ile	4.097IleAla: 4.097 ± 0.021	1.437IleCys: 1.437 ± 0.011	5.264IleAsp: 5.264 ± 0.022	6.029IleGlu: 6.029 ± 0.023	4.637IlePhe: 4.637 ± 0.029	3.044IleGly: 3.044 ± 0.019	1.975IleHis: 1.975 ± 0.015	6.542IleIle: 6.542 ± 0.033	5.624IleLys: 5.624 ± 0.027	7.556IleLeu: 7.556 ± 0.036	1.581IleMet: 1.581 ± 0.012	5.648IleAsn: 5.648 ± 0.027	3.944IlePro: 3.944 ± 0.022	3.681IleGln: 3.681 ± 0.021	3.051IleArg: 3.051 ± 0.019	7.548IleSer: 7.548 ± 0.032	4.156IleThr: 4.156 ± 0.02	4.33IleVal: 4.33 ± 0.019	0.629IleTrp: 0.629 ± 0.007	2.77IleTyr: 2.77 ± 0.019	0.013IleXaa: 0.013 ± 0.001
Lys	3.435LysAla: 3.435 ± 0.022	1.205LysCys: 1.205 ± 0.012	3.613LysAsp: 3.613 ± 0.023	5.522LysGlu: 5.522 ± 0.037	3.426LysPhe: 3.426 ± 0.018	2.376LysGly: 2.376 ± 0.015	1.41LysHis: 1.41 ± 0.011	6.532LysIle: 6.532 ± 0.028	6.927LysLys: 6.927 ± 0.071	6.718LysLeu: 6.718 ± 0.029	2.069LysMet: 2.069 ± 0.015	5.577LysAsn: 5.577 ± 0.031	2.753LysPro: 2.753 ± 0.019	3.025LysGln: 3.025 ± 0.023	3.065LysArg: 3.065 ± 0.021	5.906LysSer: 5.906 ± 0.033	3.947LysThr: 3.947 ± 0.022	3.584LysVal: 3.584 ± 0.019	0.618LysTrp: 0.618 ± 0.007	2.903LysTyr: 2.903 ± 0.016	0.016LysXaa: 0.016 ± 0.002
Leu	4.39LeuAla: 4.39 ± 0.022	1.558LeuCys: 1.558 ± 0.012	4.513LeuAsp: 4.513 ± 0.022	5.509LeuGlu: 5.509 ± 0.03	5.542LeuPhe: 5.542 ± 0.03	2.922LeuGly: 2.922 ± 0.019	2.092LeuHis: 2.092 ± 0.013	7.48LeuIle: 7.48 ± 0.031	7.132LeuLys: 7.132 ± 0.034	8.934LeuLeu: 8.934 ± 0.038	2.17LeuMet: 2.17 ± 0.015	6.502LeuAsn: 6.502 ± 0.029	4.047LeuPro: 4.047 ± 0.021	4.018LeuGln: 4.018 ± 0.026	3.641LeuArg: 3.641 ± 0.02	8.174LeuSer: 8.174 ± 0.035	4.943LeuThr: 4.943 ± 0.023	4.27LeuVal: 4.27 ± 0.023	0.627LeuTrp: 0.627 ± 0.007	3.109LeuTyr: 3.109 ± 0.019	0.011LeuXaa: 0.011 ± 0.001
Met	1.144MetAla: 1.144 ± 0.011	0.322MetCys: 0.322 ± 0.005	0.908MetAsp: 0.908 ± 0.01	1.284MetGlu: 1.284 ± 0.011	1.069MetPhe: 1.069 ± 0.011	0.659MetGly: 0.659 ± 0.007	0.414MetHis: 0.414 ± 0.006	1.987MetIle: 1.987 ± 0.015	2.398MetLys: 2.398 ± 0.015	1.869MetLeu: 1.869 ± 0.015	0.704MetMet: 0.704 ± 0.008	2.048MetAsn: 2.048 ± 0.016	0.891MetPro: 0.891 ± 0.009	0.895MetGln: 0.895 ± 0.01	0.95MetArg: 0.95 ± 0.009	1.796MetSer: 1.796 ± 0.011	1.363MetThr: 1.363 ± 0.01	0.927MetVal: 0.927 ± 0.009	0.17MetTrp: 0.17 ± 0.004	0.633MetTyr: 0.633 ± 0.007	0.003MetXaa: 0.003 ± 0.001
Asn	2.997AsnAla: 2.997 ± 0.018	1.106AsnCys: 1.106 ± 0.012	4.686AsnAsp: 4.686 ± 0.025	5.939AsnGlu: 5.939 ± 0.037	3.713AsnPhe: 3.713 ± 0.02	2.808AsnGly: 2.808 ± 0.018	1.726AsnHis: 1.726 ± 0.014	5.72AsnIle: 5.72 ± 0.029	4.618AsnLys: 4.618 ± 0.027	5.981AsnLeu: 5.981 ± 0.026	1.285AsnMet: 1.285 ± 0.011	5.953AsnAsn: 5.953 ± 0.045	2.828AsnPro: 2.828 ± 0.017	3.497AsnGln: 3.497 ± 0.023	2.404AsnArg: 2.404 ± 0.015	6.518AsnSer: 6.518 ± 0.034	3.249AsnThr: 3.249 ± 0.018	3.292AsnVal: 3.292 ± 0.016	0.482AsnTrp: 0.482 ± 0.006	2.556AsnTyr: 2.556 ± 0.016	0.014AsnXaa: 0.014 ± 0.001
Pro	1.801ProAla: 1.801 ± 0.016	0.423ProCys: 0.423 ± 0.006	2.167ProAsp: 2.167 ± 0.014	3.047ProGlu: 3.047 ± 0.016	2.32ProPhe: 2.32 ± 0.016	1.343ProGly: 1.343 ± 0.015	0.86ProHis: 0.86 ± 0.01	3.392ProIle: 3.392 ± 0.02	3.243ProLys: 3.243 ± 0.023	3.571ProLeu: 3.571 ± 0.019	0.804ProMet: 0.804 ± 0.007	2.997ProAsn: 2.997 ± 0.02	2.821ProPro: 2.821 ± 0.036	1.969ProGln: 1.969 ± 0.018	1.494ProArg: 1.494 ± 0.014	3.609ProSer: 3.609 ± 0.023	2.428ProThr: 2.428 ± 0.018	2.047ProVal: 2.047 ± 0.013	0.293ProTrp: 0.293 ± 0.005	1.299ProTyr: 1.299 ± 0.011	0.007ProXaa: 0.007 ± 0.001
Gln	1.898GlnAla: 1.898 ± 0.014	0.654GlnCys: 0.654 ± 0.007	1.546GlnAsp: 1.546 ± 0.012	2.645GlnGlu: 2.645 ± 0.021	2.321GlnPhe: 2.321 ± 0.016	1.112GlnGly: 1.112 ± 0.01	0.835GlnHis: 0.835 ± 0.008	4.19GlnIle: 4.19 ± 0.024	3.972GlnLys: 3.972 ± 0.024	4.143GlnLeu: 4.143 ± 0.025	1.261GlnMet: 1.261 ± 0.012	3.924GlnAsn: 3.924 ± 0.029	1.755GlnPro: 1.755 ± 0.019	2.996GlnGln: 2.996 ± 0.042	1.835GlnArg: 1.835 ± 0.014	3.278GlnSer: 3.278 ± 0.019	2.457GlnThr: 2.457 ± 0.017	1.773GlnVal: 1.773 ± 0.012	0.321GlnTrp: 0.321 ± 0.005	1.513GlnTyr: 1.513 ± 0.012	0.008GlnXaa: 0.008 ± 0.001
Arg	1.896ArgAla: 1.896 ± 0.016	0.614ArgCys: 0.614 ± 0.007	1.903ArgAsp: 1.903 ± 0.014	2.404ArgGlu: 2.404 ± 0.017	2.047ArgPhe: 2.047 ± 0.013	1.432ArgGly: 1.432 ± 0.013	0.812ArgHis: 0.812 ± 0.009	3.159ArgIle: 3.159 ± 0.016	3.259ArgLys: 3.259 ± 0.024	3.406ArgLeu: 3.406 ± 0.02	0.89ArgMet: 0.89 ± 0.009	2.677ArgAsn: 2.677 ± 0.017	1.512ArgPro: 1.512 ± 0.013	1.658ArgGln: 1.658 ± 0.014	2.089ArgArg: 2.089 ± 0.019	2.934ArgSer: 2.934 ± 0.017	1.839ArgThr: 1.839 ± 0.014	1.825ArgVal: 1.825 ± 0.013	0.366ArgTrp: 0.366 ± 0.007	1.362ArgTyr: 1.362 ± 0.01	0.007ArgXaa: 0.007 ± 0.001
Ser	3.699SerAla: 3.699 ± 0.021	1.181SerCys: 1.181 ± 0.013	4.672SerAsp: 4.672 ± 0.025	5.083SerGlu: 5.083 ± 0.033	5.119SerPhe: 5.119 ± 0.024	2.98SerGly: 2.98 ± 0.02	1.939SerHis: 1.939 ± 0.013	7.179SerIle: 7.179 ± 0.028	5.97SerLys: 5.97 ± 0.032	8.345SerLeu: 8.345 ± 0.031	1.791SerMet: 1.791 ± 0.013	6.154SerAsn: 6.154 ± 0.033	3.815SerPro: 3.815 ± 0.032	3.971SerGln: 3.971 ± 0.023	2.976SerArg: 2.976 ± 0.018	8.551SerSer: 8.551 ± 0.059	4.53SerThr: 4.53 ± 0.024	3.889SerVal: 3.889 ± 0.019	0.518SerTrp: 0.518 ± 0.007	2.672SerTyr: 2.672 ± 0.016	0.015SerXaa: 0.015 ± 0.002
Thr	2.65ThrAla: 2.65 ± 0.015	0.688ThrCys: 0.688 ± 0.01	2.641ThrAsp: 2.641 ± 0.016	3.301ThrGlu: 3.301 ± 0.019	3.06ThrPhe: 3.06 ± 0.017	1.985ThrGly: 1.985 ± 0.016	1.03ThrHis: 1.03 ± 0.008	4.504ThrIle: 4.504 ± 0.025	3.878ThrLys: 3.878 ± 0.021	4.676ThrLeu: 4.676 ± 0.02	1.074ThrMet: 1.074 ± 0.009	3.65ThrAsn: 3.65 ± 0.021	2.588ThrPro: 2.588 ± 0.022	2.216ThrGln: 2.216 ± 0.016	1.841ThrArg: 1.841 ± 0.013	4.272ThrSer: 4.272 ± 0.023	2.97ThrThr: 2.97 ± 0.022	2.706ThrVal: 2.706 ± 0.016	0.326ThrTrp: 0.326 ± 0.005	1.502ThrTyr: 1.502 ± 0.011	0.01ThrXaa: 0.01 ± 0.001
Val	2.623ValAla: 2.623 ± 0.016	0.829ValCys: 0.829 ± 0.01	2.909ValAsp: 2.909 ± 0.016	3.11ValGlu: 3.11 ± 0.019	2.937ValPhe: 2.937 ± 0.018	1.896ValGly: 1.896 ± 0.016	1.049ValHis: 1.049 ± 0.009	3.853ValIle: 3.853 ± 0.018	3.503ValLys: 3.503 ± 0.018	4.427ValLeu: 4.427 ± 0.022	1.074ValMet: 1.074 ± 0.009	3.215ValAsn: 3.215 ± 0.017	2.074ValPro: 2.074 ± 0.014	1.966ValGln: 1.966 ± 0.014	1.864ValArg: 1.864 ± 0.014	4.156ValSer: 4.156 ± 0.02	2.586ValThr: 2.586 ± 0.017	2.817ValVal: 2.817 ± 0.019	0.399ValTrp: 0.399 ± 0.005	1.662ValTyr: 1.662 ± 0.012	0.008ValXaa: 0.008 ± 0.001
Trp	0.414TrpAla: 0.414 ± 0.006	0.154TrpCys: 0.154 ± 0.004	0.423TrpAsp: 0.423 ± 0.007	0.439TrpGlu: 0.439 ± 0.005	0.37TrpPhe: 0.37 ± 0.006	0.312TrpGly: 0.312 ± 0.006	0.154TrpHis: 0.154 ± 0.003	0.636TrpIle: 0.636 ± 0.008	0.587TrpLys: 0.587 ± 0.007	0.602TrpLeu: 0.602 ± 0.007	0.227TrpMet: 0.227 ± 0.004	0.516TrpAsn: 0.516 ± 0.007	0.253TrpPro: 0.253 ± 0.005	0.244TrpGln: 0.244 ± 0.005	0.343TrpArg: 0.343 ± 0.006	0.623TrpSer: 0.623 ± 0.006	0.443TrpThr: 0.443 ± 0.006	0.367TrpVal: 0.367 ± 0.006	0.075TrpTrp: 0.075 ± 0.003	0.242TrpTyr: 0.242 ± 0.004	0.002TrpXaa: 0.002 ± 0.0
Tyr	1.65TyrAla: 1.65 ± 0.014	0.631TyrCys: 0.631 ± 0.007	2.106TyrAsp: 2.106 ± 0.015	2.252TyrGlu: 2.252 ± 0.014	2.256TyrPhe: 2.256 ± 0.016	1.501TyrGly: 1.501 ± 0.012	0.868TyrHis: 0.868 ± 0.008	2.629TyrIle: 2.629 ± 0.018	2.034TyrLys: 2.034 ± 0.014	3.447TyrLeu: 3.447 ± 0.02	0.686TyrMet: 0.686 ± 0.008	2.085TyrAsn: 2.085 ± 0.015	1.327TyrPro: 1.327 ± 0.01	1.693TyrGln: 1.693 ± 0.013	1.326TyrArg: 1.326 ± 0.011	3.095TyrSer: 3.095 ± 0.019	1.528TyrThr: 1.528 ± 0.012	1.681TyrVal: 1.681 ± 0.013	0.244TyrTrp: 0.244 ± 0.005	1.432TyrTyr: 1.432 ± 0.015	0.005TyrXaa: 0.005 ± 0.001
Xaa	0.007XaaAla: 0.007 ± 0.001	0.003XaaCys: 0.003 ± 0.001	0.01XaaAsp: 0.01 ± 0.001	0.013XaaGlu: 0.013 ± 0.001	0.009XaaPhe: 0.009 ± 0.001	0.008XaaGly: 0.008 ± 0.001	0.006XaaHis: 0.006 ± 0.001	0.013XaaIle: 0.013 ± 0.001	0.014XaaLys: 0.014 ± 0.001	0.011XaaLeu: 0.011 ± 0.001	0.003XaaMet: 0.003 ± 0.001	0.015XaaAsn: 0.015 ± 0.001	0.007XaaPro: 0.007 ± 0.001	0.008XaaGln: 0.008 ± 0.001	0.006XaaArg: 0.006 ± 0.001	0.012XaaSer: 0.012 ± 0.001	0.011XaaThr: 0.011 ± 0.001	0.01XaaVal: 0.01 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.007XaaTyr: 0.007 ± 0.001	1.582XaaXaa: 1.582 ± 0.244

Statistics based on 24634 proteins (13073236 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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