Amino acid dipepetide frequency for Rodentolepis nana (Dwarf tapeworm) (Hymenolepis nana)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.449AlaAla: 5.449 ± 0.054	1.269AlaCys: 1.269 ± 0.017	3.263AlaAsp: 3.263 ± 0.028	4.014AlaGlu: 4.014 ± 0.035	2.833AlaPhe: 2.833 ± 0.028	3.31AlaGly: 3.31 ± 0.033	1.319AlaHis: 1.319 ± 0.017	3.801AlaIle: 3.801 ± 0.028	3.561AlaLys: 3.561 ± 0.032	6.299AlaLeu: 6.299 ± 0.047	1.433AlaMet: 1.433 ± 0.017	3.095AlaAsn: 3.095 ± 0.025	3.148AlaPro: 3.148 ± 0.03	2.324AlaGln: 2.324 ± 0.023	3.218AlaArg: 3.218 ± 0.027	6.163AlaSer: 6.163 ± 0.044	3.893AlaThr: 3.893 ± 0.026	4.136AlaVal: 4.136 ± 0.035	0.622AlaTrp: 0.622 ± 0.012	1.776AlaTyr: 1.776 ± 0.021	0.001AlaXaa: 0.001 ± 0.0
Cys	1.156CysAla: 1.156 ± 0.016	0.575CysCys: 0.575 ± 0.013	1.033CysAsp: 1.033 ± 0.019	1.175CysGlu: 1.175 ± 0.025	0.901CysPhe: 0.901 ± 0.013	1.266CysGly: 1.266 ± 0.018	0.525CysHis: 0.525 ± 0.01	1.168CysIle: 1.168 ± 0.018	0.971CysLys: 0.971 ± 0.018	2.315CysLeu: 2.315 ± 0.028	0.397CysMet: 0.397 ± 0.009	0.834CysAsn: 0.834 ± 0.014	1.162CysPro: 1.162 ± 0.019	0.863CysGln: 0.863 ± 0.016	1.225CysArg: 1.225 ± 0.019	1.719CysSer: 1.719 ± 0.024	0.981CysThr: 0.981 ± 0.014	1.213CysVal: 1.213 ± 0.019	0.207CysTrp: 0.207 ± 0.007	0.572CysTyr: 0.572 ± 0.013	0.001CysXaa: 0.001 ± 0.0
Asp	3.276AspAla: 3.276 ± 0.024	1.03AspCys: 1.03 ± 0.017	3.475AspAsp: 3.475 ± 0.053	3.983AspGlu: 3.983 ± 0.038	2.455AspPhe: 2.455 ± 0.023	3.126AspGly: 3.126 ± 0.039	1.018AspHis: 1.018 ± 0.014	3.112AspIle: 3.112 ± 0.029	2.456AspLys: 2.456 ± 0.026	5.11AspLeu: 5.11 ± 0.038	1.046AspMet: 1.046 ± 0.015	2.167AspAsn: 2.167 ± 0.021	2.676AspPro: 2.676 ± 0.028	1.775AspGln: 1.775 ± 0.018	2.592AspArg: 2.592 ± 0.022	4.507AspSer: 4.507 ± 0.037	2.449AspThr: 2.449 ± 0.022	3.227AspVal: 3.227 ± 0.027	0.652AspTrp: 0.652 ± 0.012	1.652AspTyr: 1.652 ± 0.021	0.001AspXaa: 0.001 ± 0.0
Glu	4.442GluAla: 4.442 ± 0.035	1.164GluCys: 1.164 ± 0.021	3.741GluAsp: 3.741 ± 0.037	5.825GluGlu: 5.825 ± 0.058	2.437GluPhe: 2.437 ± 0.021	3.146GluGly: 3.146 ± 0.034	1.246GluHis: 1.246 ± 0.017	3.903GluIle: 3.903 ± 0.03	4.081GluLys: 4.081 ± 0.039	5.609GluLeu: 5.609 ± 0.05	1.65GluMet: 1.65 ± 0.021	3.351GluAsn: 3.351 ± 0.032	2.447GluPro: 2.447 ± 0.031	2.225GluGln: 2.225 ± 0.025	3.467GluArg: 3.467 ± 0.032	5.156GluSer: 5.156 ± 0.043	3.382GluThr: 3.382 ± 0.033	3.99GluVal: 3.99 ± 0.035	0.609GluTrp: 0.609 ± 0.011	1.712GluTyr: 1.712 ± 0.021	0.002GluXaa: 0.002 ± 0.001
Phe	2.603PheAla: 2.603 ± 0.024	0.93PheCys: 0.93 ± 0.015	2.356PheAsp: 2.356 ± 0.023	2.384PheGlu: 2.384 ± 0.025	1.918PhePhe: 1.918 ± 0.024	2.418PheGly: 2.418 ± 0.025	1.089PheHis: 1.089 ± 0.015	2.438PheIle: 2.438 ± 0.025	1.988PheLys: 1.988 ± 0.022	4.108PheLeu: 4.108 ± 0.034	0.885PheMet: 0.885 ± 0.016	1.968PheAsn: 1.968 ± 0.018	2.083PhePro: 2.083 ± 0.022	1.58PheGln: 1.58 ± 0.018	2.279PheArg: 2.279 ± 0.02	3.803PheSer: 3.803 ± 0.032	2.409PheThr: 2.409 ± 0.026	2.589PheVal: 2.589 ± 0.026	0.458PheTrp: 0.458 ± 0.011	1.43PheTyr: 1.43 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	3.247GlyAla: 3.247 ± 0.03	1.098GlyCys: 1.098 ± 0.017	3.078GlyAsp: 3.078 ± 0.04	3.354GlyGlu: 3.354 ± 0.06	2.341GlyPhe: 2.341 ± 0.027	4.534GlyGly: 4.534 ± 0.057	1.349GlyHis: 1.349 ± 0.019	3.07GlyIle: 3.07 ± 0.026	2.905GlyLys: 2.905 ± 0.025	4.781GlyLeu: 4.781 ± 0.037	1.203GlyMet: 1.203 ± 0.015	2.646GlyAsn: 2.646 ± 0.023	2.496GlyPro: 2.496 ± 0.094	1.957GlyGln: 1.957 ± 0.023	3.122GlyArg: 3.122 ± 0.03	5.069GlySer: 5.069 ± 0.042	2.94GlyThr: 2.94 ± 0.028	3.516GlyVal: 3.516 ± 0.024	0.58GlyTrp: 0.58 ± 0.012	1.7GlyTyr: 1.7 ± 0.024	0.001GlyXaa: 0.001 ± 0.0
His	1.25HisAla: 1.25 ± 0.014	0.563HisCys: 0.563 ± 0.012	0.955HisAsp: 0.955 ± 0.015	1.228HisGlu: 1.228 ± 0.017	1.187HisPhe: 1.187 ± 0.015	1.203HisGly: 1.203 ± 0.018	0.893HisHis: 0.893 ± 0.02	1.296HisIle: 1.296 ± 0.016	1.054HisLys: 1.054 ± 0.015	2.676HisLeu: 2.676 ± 0.025	0.489HisMet: 0.489 ± 0.011	0.985HisAsn: 0.985 ± 0.016	1.459HisPro: 1.459 ± 0.019	1.147HisGln: 1.147 ± 0.018	1.597HisArg: 1.597 ± 0.02	2.224HisSer: 2.224 ± 0.025	1.157HisThr: 1.157 ± 0.018	1.232HisVal: 1.232 ± 0.017	0.289HisTrp: 0.289 ± 0.008	0.787HisTyr: 0.787 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.714IleAla: 3.714 ± 0.031	1.341IleCys: 1.341 ± 0.019	3.149IleAsp: 3.149 ± 0.023	3.521IleGlu: 3.521 ± 0.032	2.56IlePhe: 2.56 ± 0.027	2.976IleGly: 2.976 ± 0.025	1.34IleHis: 1.34 ± 0.016	3.133IleIle: 3.133 ± 0.033	2.807IleLys: 2.807 ± 0.026	5.325IleLeu: 5.325 ± 0.041	1.114IleMet: 1.114 ± 0.017	2.585IleAsn: 2.585 ± 0.023	3.302IlePro: 3.302 ± 0.026	2.19IleGln: 2.19 ± 0.024	3.26IleArg: 3.26 ± 0.027	5.352IleSer: 5.352 ± 0.032	3.161IleThr: 3.161 ± 0.027	3.269IleVal: 3.269 ± 0.029	0.592IleTrp: 0.592 ± 0.011	1.755IleTyr: 1.755 ± 0.022	0.001IleXaa: 0.001 ± 0.001
Lys	3.545LysAla: 3.545 ± 0.033	1.076LysCys: 1.076 ± 0.02	2.553LysAsp: 2.553 ± 0.025	3.758LysGlu: 3.758 ± 0.036	1.993LysPhe: 1.993 ± 0.021	2.301LysGly: 2.301 ± 0.037	1.262LysHis: 1.262 ± 0.017	3.019LysIle: 3.019 ± 0.027	3.619LysLys: 3.619 ± 0.035	4.959LysLeu: 4.959 ± 0.041	1.375LysMet: 1.375 ± 0.016	2.474LysAsn: 2.474 ± 0.023	2.842LysPro: 2.842 ± 0.034	2.052LysGln: 2.052 ± 0.021	3.681LysArg: 3.681 ± 0.03	4.828LysSer: 4.828 ± 0.038	2.996LysThr: 2.996 ± 0.028	3.04LysVal: 3.04 ± 0.028	0.57LysTrp: 0.57 ± 0.01	1.555LysTyr: 1.555 ± 0.02	0.001LysXaa: 0.001 ± 0.0
Leu	6.406LeuAla: 6.406 ± 0.039	1.943LeuCys: 1.943 ± 0.022	4.765LeuAsp: 4.765 ± 0.037	5.97LeuGlu: 5.97 ± 0.055	3.922LeuPhe: 3.922 ± 0.033	4.5LeuGly: 4.5 ± 0.032	2.402LeuHis: 2.402 ± 0.026	5.479LeuIle: 5.479 ± 0.041	5.506LeuLys: 5.506 ± 0.04	9.747LeuLeu: 9.747 ± 0.073	2.045LeuMet: 2.045 ± 0.021	4.593LeuAsn: 4.593 ± 0.031	5.693LeuPro: 5.693 ± 0.042	4.134LeuGln: 4.134 ± 0.04	5.867LeuArg: 5.867 ± 0.042	8.574LeuSer: 8.574 ± 0.06	5.335LeuThr: 5.335 ± 0.035	5.288LeuVal: 5.288 ± 0.037	0.938LeuTrp: 0.938 ± 0.016	2.46LeuTyr: 2.46 ± 0.024	0.001LeuXaa: 0.001 ± 0.0
Met	1.622MetAla: 1.622 ± 0.018	0.383MetCys: 0.383 ± 0.009	1.238MetAsp: 1.238 ± 0.016	1.659MetGlu: 1.659 ± 0.017	0.729MetPhe: 0.729 ± 0.012	1.182MetGly: 1.182 ± 0.017	0.504MetHis: 0.504 ± 0.009	1.074MetIle: 1.074 ± 0.015	1.291MetLys: 1.291 ± 0.016	1.962MetLeu: 1.962 ± 0.02	0.522MetMet: 0.522 ± 0.01	1.107MetAsn: 1.107 ± 0.016	1.206MetPro: 1.206 ± 0.018	0.882MetGln: 0.882 ± 0.013	1.258MetArg: 1.258 ± 0.016	1.873MetSer: 1.873 ± 0.02	1.282MetThr: 1.282 ± 0.016	1.259MetVal: 1.259 ± 0.014	0.203MetTrp: 0.203 ± 0.007	0.498MetTyr: 0.498 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.147AsnAla: 3.147 ± 0.025	0.994AsnCys: 0.994 ± 0.018	2.392AsnAsp: 2.392 ± 0.022	3.065AsnGlu: 3.065 ± 0.028	2.143AsnPhe: 2.143 ± 0.022	3.097AsnGly: 3.097 ± 0.03	1.055AsnHis: 1.055 ± 0.016	2.606AsnIle: 2.606 ± 0.025	2.155AsnLys: 2.155 ± 0.022	4.61AsnLeu: 4.61 ± 0.03	0.946AsnMet: 0.946 ± 0.015	2.203AsnAsn: 2.203 ± 0.026	2.689AsnPro: 2.689 ± 0.031	1.982AsnGln: 1.982 ± 0.025	2.694AsnArg: 2.694 ± 0.022	4.647AsnSer: 4.647 ± 0.035	2.477AsnThr: 2.477 ± 0.024	2.71AsnVal: 2.71 ± 0.026	0.535AsnTrp: 0.535 ± 0.01	1.425AsnTyr: 1.425 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	3.007ProAla: 3.007 ± 0.025	0.872ProCys: 0.872 ± 0.021	2.672ProAsp: 2.672 ± 0.028	3.264ProGlu: 3.264 ± 0.027	2.104ProPhe: 2.104 ± 0.021	2.859ProGly: 2.859 ± 0.077	1.307ProHis: 1.307 ± 0.021	3.14ProIle: 3.14 ± 0.03	2.833ProLys: 2.833 ± 0.033	4.943ProLeu: 4.943 ± 0.037	1.11ProMet: 1.11 ± 0.015	2.683ProAsn: 2.683 ± 0.026	5.383ProPro: 5.383 ± 0.079	2.396ProGln: 2.396 ± 0.031	2.819ProArg: 2.819 ± 0.03	6.019ProSer: 6.019 ± 0.053	3.69ProThr: 3.69 ± 0.039	3.23ProVal: 3.23 ± 0.033	0.5ProTrp: 0.5 ± 0.009	1.378ProTyr: 1.378 ± 0.016	0.001ProXaa: 0.001 ± 0.0
Gln	2.45GlnAla: 2.45 ± 0.024	0.763GlnCys: 0.763 ± 0.014	1.522GlnAsp: 1.522 ± 0.018	2.256GlnGlu: 2.256 ± 0.025	1.504GlnPhe: 1.504 ± 0.02	1.701GlnGly: 1.701 ± 0.034	1.083GlnHis: 1.083 ± 0.019	2.32GlnIle: 2.32 ± 0.025	2.114GlnLys: 2.114 ± 0.02	4.066GlnLeu: 4.066 ± 0.034	1.057GlnMet: 1.057 ± 0.016	1.992GlnAsn: 1.992 ± 0.022	2.382GlnPro: 2.382 ± 0.031	2.865GlnGln: 2.865 ± 0.065	2.55GlnArg: 2.55 ± 0.022	3.654GlnSer: 3.654 ± 0.032	2.315GlnThr: 2.315 ± 0.023	2.252GlnVal: 2.252 ± 0.023	0.496GlnTrp: 0.496 ± 0.011	1.031GlnTyr: 1.031 ± 0.015	0.001GlnXaa: 0.001 ± 0.001
Arg	3.228ArgAla: 3.228 ± 0.025	1.26ArgCys: 1.26 ± 0.022	2.582ArgAsp: 2.582 ± 0.025	3.254ArgGlu: 3.254 ± 0.028	2.432ArgPhe: 2.432 ± 0.026	3.03ArgGly: 3.03 ± 0.046	1.593ArgHis: 1.593 ± 0.021	3.349ArgIle: 3.349 ± 0.03	3.497ArgLys: 3.497 ± 0.028	6.191ArgLeu: 6.191 ± 0.045	1.283ArgMet: 1.283 ± 0.018	2.73ArgAsn: 2.73 ± 0.027	2.856ArgPro: 2.856 ± 0.029	2.533ArgGln: 2.533 ± 0.024	4.966ArgArg: 4.966 ± 0.046	4.971ArgSer: 4.971 ± 0.039	2.84ArgThr: 2.84 ± 0.023	3.197ArgVal: 3.197 ± 0.027	0.629ArgTrp: 0.629 ± 0.011	1.686ArgTyr: 1.686 ± 0.019	0.001ArgXaa: 0.001 ± 0.0
Ser	6.017SerAla: 6.017 ± 0.045	1.658SerCys: 1.658 ± 0.023	4.716SerAsp: 4.716 ± 0.04	5.329SerGlu: 5.329 ± 0.046	3.467SerPhe: 3.467 ± 0.028	5.613SerGly: 5.613 ± 0.035	2.109SerHis: 2.109 ± 0.023	4.948SerIle: 4.948 ± 0.033	4.746SerLys: 4.746 ± 0.034	8.422SerLeu: 8.422 ± 0.054	1.91SerMet: 1.91 ± 0.018	4.694SerAsn: 4.694 ± 0.034	5.581SerPro: 5.581 ± 0.052	3.742SerGln: 3.742 ± 0.036	5.171SerArg: 5.171 ± 0.042	11.607SerSer: 11.607 ± 0.102	6.358SerThr: 6.358 ± 0.057	5.365SerVal: 5.365 ± 0.038	0.869SerTrp: 0.869 ± 0.015	2.166SerTyr: 2.166 ± 0.025	0.002SerXaa: 0.002 ± 0.001
Thr	3.984ThrAla: 3.984 ± 0.031	1.116ThrCys: 1.116 ± 0.017	2.814ThrAsp: 2.814 ± 0.027	3.369ThrGlu: 3.369 ± 0.033	2.285ThrPhe: 2.285 ± 0.023	3.34ThrGly: 3.34 ± 0.03	1.24ThrHis: 1.24 ± 0.018	3.046ThrIle: 3.046 ± 0.024	2.766ThrLys: 2.766 ± 0.024	5.082ThrLeu: 5.082 ± 0.034	1.146ThrMet: 1.146 ± 0.015	2.736ThrAsn: 2.736 ± 0.026	3.758ThrPro: 3.758 ± 0.037	2.06ThrGln: 2.06 ± 0.025	2.745ThrArg: 2.745 ± 0.024	6.005ThrSer: 6.005 ± 0.053	4.038ThrThr: 4.038 ± 0.047	3.528ThrVal: 3.528 ± 0.029	0.578ThrTrp: 0.578 ± 0.011	1.532ThrTyr: 1.532 ± 0.02	0.001ThrXaa: 0.001 ± 0.0
Val	4.079ValAla: 4.079 ± 0.032	1.329ValCys: 1.329 ± 0.02	3.487ValAsp: 3.487 ± 0.027	3.949ValGlu: 3.949 ± 0.032	2.572ValPhe: 2.572 ± 0.023	3.317ValGly: 3.317 ± 0.028	1.332ValHis: 1.332 ± 0.015	3.352ValIle: 3.352 ± 0.03	3.201ValLys: 3.201 ± 0.03	5.23ValLeu: 5.23 ± 0.038	1.227ValMet: 1.227 ± 0.016	2.929ValAsn: 2.929 ± 0.024	3.104ValPro: 3.104 ± 0.028	2.136ValGln: 2.136 ± 0.025	3.072ValArg: 3.072 ± 0.025	5.108ValSer: 5.108 ± 0.038	3.392ValThr: 3.392 ± 0.032	3.961ValVal: 3.961 ± 0.036	0.609ValTrp: 0.609 ± 0.013	1.77ValTyr: 1.77 ± 0.021	0.001ValXaa: 0.001 ± 0.0
Trp	0.537TrpAla: 0.537 ± 0.01	0.233TrpCys: 0.233 ± 0.006	0.516TrpAsp: 0.516 ± 0.01	0.559TrpGlu: 0.559 ± 0.011	0.477TrpPhe: 0.477 ± 0.011	0.455TrpGly: 0.455 ± 0.01	0.26TrpHis: 0.26 ± 0.007	0.646TrpIle: 0.646 ± 0.011	0.655TrpLys: 0.655 ± 0.012	1.105TrpLeu: 1.105 ± 0.017	0.285TrpMet: 0.285 ± 0.009	0.572TrpAsn: 0.572 ± 0.011	0.523TrpPro: 0.523 ± 0.011	0.396TrpGln: 0.396 ± 0.009	0.749TrpArg: 0.749 ± 0.012	0.891TrpSer: 0.891 ± 0.015	0.598TrpThr: 0.598 ± 0.012	0.522TrpVal: 0.522 ± 0.01	0.144TrpTrp: 0.144 ± 0.005	0.306TrpTyr: 0.306 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.768TyrAla: 1.768 ± 0.019	0.659TyrCys: 0.659 ± 0.013	1.479TyrAsp: 1.479 ± 0.018	1.67TyrGlu: 1.67 ± 0.02	1.459TyrPhe: 1.459 ± 0.018	1.616TyrGly: 1.616 ± 0.02	0.743TyrHis: 0.743 ± 0.012	1.546TyrIle: 1.546 ± 0.02	1.292TyrLys: 1.292 ± 0.017	3.025TyrLeu: 3.025 ± 0.027	0.61TyrMet: 0.61 ± 0.012	1.228TyrAsn: 1.228 ± 0.017	1.422TyrPro: 1.422 ± 0.018	1.132TyrGln: 1.132 ± 0.016	1.771TyrArg: 1.771 ± 0.021	2.32TyrSer: 2.32 ± 0.023	1.474TyrThr: 1.474 ± 0.019	1.629TyrVal: 1.629 ± 0.02	0.348TyrTrp: 0.348 ± 0.009	0.999TyrTyr: 0.999 ± 0.017	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.002XaaIle: 0.002 ± 0.001	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.002XaaPro: 0.002 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.001	0.001XaaSer: 0.001 ± 0.0	0.002XaaThr: 0.002 ± 0.001	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.098XaaXaa: 0.098 ± 0.03

Statistics based on 13592 proteins (5151847 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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