Amino acid dipepetide frequency for Sphingobacterium olei

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.258AlaAla: 5.258 ± 0.078	0.55AlaCys: 0.55 ± 0.018	4.178AlaAsp: 4.178 ± 0.06	4.288AlaGlu: 4.288 ± 0.054	3.176AlaPhe: 3.176 ± 0.042	4.832AlaGly: 4.832 ± 0.071	1.278AlaHis: 1.278 ± 0.03	5.287AlaIle: 5.287 ± 0.063	4.39AlaLys: 4.39 ± 0.063	6.621AlaLeu: 6.621 ± 0.073	1.509AlaMet: 1.509 ± 0.034	3.717AlaAsn: 3.717 ± 0.057	2.119AlaPro: 2.119 ± 0.042	2.816AlaGln: 2.816 ± 0.042	2.644AlaArg: 2.644 ± 0.044	4.519AlaSer: 4.519 ± 0.059	3.97AlaThr: 3.97 ± 0.063	4.613AlaVal: 4.613 ± 0.063	0.82AlaTrp: 0.82 ± 0.023	3.065AlaTyr: 3.065 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.463CysAla: 0.463 ± 0.018	0.121CysCys: 0.121 ± 0.01	0.335CysAsp: 0.335 ± 0.014	0.382CysGlu: 0.382 ± 0.017	0.335CysPhe: 0.335 ± 0.014	0.553CysGly: 0.553 ± 0.021	0.165CysHis: 0.165 ± 0.012	0.538CysIle: 0.538 ± 0.02	0.379CysLys: 0.379 ± 0.016	0.655CysLeu: 0.655 ± 0.02	0.17CysMet: 0.17 ± 0.011	0.329CysAsn: 0.329 ± 0.014	0.277CysPro: 0.277 ± 0.015	0.24CysGln: 0.24 ± 0.013	0.292CysArg: 0.292 ± 0.016	0.494CysSer: 0.494 ± 0.018	0.416CysThr: 0.416 ± 0.016	0.422CysVal: 0.422 ± 0.017	0.07CysTrp: 0.07 ± 0.007	0.313CysTyr: 0.313 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	3.8AspAla: 3.8 ± 0.054	0.327AspCys: 0.327 ± 0.014	2.803AspAsp: 2.803 ± 0.044	3.514AspGlu: 3.514 ± 0.043	3.241AspPhe: 3.241 ± 0.047	4.202AspGly: 4.202 ± 0.057	1.097AspHis: 1.097 ± 0.029	4.383AspIle: 4.383 ± 0.059	3.713AspLys: 3.713 ± 0.052	5.252AspLeu: 5.252 ± 0.058	1.296AspMet: 1.296 ± 0.026	2.969AspAsn: 2.969 ± 0.045	2.251AspPro: 2.251 ± 0.044	1.998AspGln: 1.998 ± 0.033	2.599AspArg: 2.599 ± 0.042	3.064AspSer: 3.064 ± 0.053	2.621AspThr: 2.621 ± 0.044	3.642AspVal: 3.642 ± 0.049	0.834AspTrp: 0.834 ± 0.021	2.771AspTyr: 2.771 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	4.197GluAla: 4.197 ± 0.055	0.308GluCys: 0.308 ± 0.014	3.126GluAsp: 3.126 ± 0.047	4.408GluGlu: 4.408 ± 0.06	2.513GluPhe: 2.513 ± 0.043	3.842GluGly: 3.842 ± 0.058	1.171GluHis: 1.171 ± 0.026	4.831GluIle: 4.831 ± 0.065	4.691GluLys: 4.691 ± 0.069	5.822GluLeu: 5.822 ± 0.067	1.491GluMet: 1.491 ± 0.033	3.728GluAsn: 3.728 ± 0.051	1.576GluPro: 1.576 ± 0.034	2.555GluGln: 2.555 ± 0.046	2.864GluArg: 2.864 ± 0.052	3.29GluSer: 3.29 ± 0.041	3.042GluThr: 3.042 ± 0.045	4.066GluVal: 4.066 ± 0.047	0.742GluTrp: 0.742 ± 0.02	2.254GluTyr: 2.254 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.119PheAla: 3.119 ± 0.05	0.391PheCys: 0.391 ± 0.015	3.032PheAsp: 3.032 ± 0.052	2.988PheGlu: 2.988 ± 0.046	2.446PhePhe: 2.446 ± 0.053	3.445PheGly: 3.445 ± 0.045	0.936PheHis: 0.936 ± 0.028	3.285PheIle: 3.285 ± 0.054	2.782PheLys: 2.782 ± 0.041	4.276PheLeu: 4.276 ± 0.065	1.068PheMet: 1.068 ± 0.027	2.829PheAsn: 2.829 ± 0.051	1.741PhePro: 1.741 ± 0.032	1.577PheGln: 1.577 ± 0.03	1.974PheArg: 1.974 ± 0.037	3.696PheSer: 3.696 ± 0.056	2.946PheThr: 2.946 ± 0.044	3.106PheVal: 3.106 ± 0.053	0.631PheTrp: 0.631 ± 0.02	2.109PheTyr: 2.109 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.603GlyAla: 4.603 ± 0.068	0.518GlyCys: 0.518 ± 0.019	3.552GlyAsp: 3.552 ± 0.056	3.711GlyGlu: 3.711 ± 0.05	3.432GlyPhe: 3.432 ± 0.049	4.947GlyGly: 4.947 ± 0.086	1.258GlyHis: 1.258 ± 0.031	5.388GlyIle: 5.388 ± 0.063	4.844GlyLys: 4.844 ± 0.061	6.262GlyLeu: 6.262 ± 0.065	1.658GlyMet: 1.658 ± 0.033	3.923GlyAsn: 3.923 ± 0.066	1.486GlyPro: 1.486 ± 0.035	2.39GlyGln: 2.39 ± 0.037	2.948GlyArg: 2.948 ± 0.047	4.554GlySer: 4.554 ± 0.065	4.271GlyThr: 4.271 ± 0.076	4.627GlyVal: 4.627 ± 0.056	1.011GlyTrp: 1.011 ± 0.029	3.209GlyTyr: 3.209 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.284HisAla: 1.284 ± 0.031	0.154HisCys: 0.154 ± 0.011	1.004HisAsp: 1.004 ± 0.029	1.044HisGlu: 1.044 ± 0.026	1.108HisPhe: 1.108 ± 0.027	1.236HisGly: 1.236 ± 0.031	0.519HisHis: 0.519 ± 0.019	1.625HisIle: 1.625 ± 0.033	0.984HisLys: 0.984 ± 0.025	1.878HisLeu: 1.878 ± 0.038	0.407HisMet: 0.407 ± 0.018	0.951HisAsn: 0.951 ± 0.025	0.923HisPro: 0.923 ± 0.026	0.777HisGln: 0.777 ± 0.021	0.87HisArg: 0.87 ± 0.022	1.095HisSer: 1.095 ± 0.03	1.134HisThr: 1.134 ± 0.025	1.23HisVal: 1.23 ± 0.03	0.263HisTrp: 0.263 ± 0.013	0.949HisTyr: 0.949 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.608IleAla: 5.608 ± 0.075	0.648IleCys: 0.648 ± 0.021	4.531IleAsp: 4.531 ± 0.06	4.515IleGlu: 4.515 ± 0.057	3.164IlePhe: 3.164 ± 0.058	5.094IleGly: 5.094 ± 0.069	1.477IleHis: 1.477 ± 0.033	4.894IleIle: 4.894 ± 0.072	4.646IleLys: 4.646 ± 0.061	6.511IleLeu: 6.511 ± 0.07	1.291IleMet: 1.291 ± 0.028	3.96IleAsn: 3.96 ± 0.06	3.245IlePro: 3.245 ± 0.039	2.786IleGln: 2.786 ± 0.048	3.247IleArg: 3.247 ± 0.042	5.188IleSer: 5.188 ± 0.061	4.126IleThr: 4.126 ± 0.059	4.556IleVal: 4.556 ± 0.066	0.827IleTrp: 0.827 ± 0.025	2.741IleTyr: 2.741 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	4.296LysAla: 4.296 ± 0.063	0.271LysCys: 0.271 ± 0.015	3.91LysAsp: 3.91 ± 0.054	4.718LysGlu: 4.718 ± 0.063	2.437LysPhe: 2.437 ± 0.04	4.118LysGly: 4.118 ± 0.053	1.222LysHis: 1.222 ± 0.027	4.863LysIle: 4.863 ± 0.056	4.664LysLys: 4.664 ± 0.068	5.648LysLeu: 5.648 ± 0.066	1.608LysMet: 1.608 ± 0.038	3.879LysAsn: 3.879 ± 0.056	2.237LysPro: 2.237 ± 0.04	2.41LysGln: 2.41 ± 0.039	2.808LysArg: 2.808 ± 0.037	3.959LysSer: 3.959 ± 0.053	3.606LysThr: 3.606 ± 0.044	4.071LysVal: 4.071 ± 0.056	0.815LysTrp: 0.815 ± 0.023	2.707LysTyr: 2.707 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	6.667LeuAla: 6.667 ± 0.076	0.758LeuCys: 0.758 ± 0.025	5.3LeuAsp: 5.3 ± 0.052	5.445LeuGlu: 5.445 ± 0.064	4.781LeuPhe: 4.781 ± 0.061	5.949LeuGly: 5.949 ± 0.064	1.771LeuHis: 1.771 ± 0.039	6.369LeuIle: 6.369 ± 0.078	6.252LeuLys: 6.252 ± 0.076	9.192LeuLeu: 9.192 ± 0.098	2.047LeuMet: 2.047 ± 0.034	5.222LeuAsn: 5.222 ± 0.059	3.925LeuPro: 3.925 ± 0.053	3.641LeuGln: 3.641 ± 0.059	4.085LeuArg: 4.085 ± 0.055	7.032LeuSer: 7.032 ± 0.07	5.389LeuThr: 5.389 ± 0.068	5.508LeuVal: 5.508 ± 0.059	0.975LeuTrp: 0.975 ± 0.027	3.669LeuTyr: 3.669 ± 0.058	0.0LeuXaa: 0.0 ± 0.0
Met	1.669MetAla: 1.669 ± 0.033	0.119MetCys: 0.119 ± 0.008	1.215MetAsp: 1.215 ± 0.028	1.408MetGlu: 1.408 ± 0.032	0.747MetPhe: 0.747 ± 0.022	1.559MetGly: 1.559 ± 0.031	0.429MetHis: 0.429 ± 0.016	1.412MetIle: 1.412 ± 0.029	1.782MetLys: 1.782 ± 0.032	2.076MetLeu: 2.076 ± 0.041	0.556MetMet: 0.556 ± 0.021	1.316MetAsn: 1.316 ± 0.03	0.941MetPro: 0.941 ± 0.023	0.857MetGln: 0.857 ± 0.022	1.003MetArg: 1.003 ± 0.023	1.367MetSer: 1.367 ± 0.027	1.145MetThr: 1.145 ± 0.027	1.384MetVal: 1.384 ± 0.029	0.223MetTrp: 0.223 ± 0.012	0.765MetTyr: 0.765 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.801AsnAla: 3.801 ± 0.052	0.312AsnCys: 0.312 ± 0.015	2.766AsnAsp: 2.766 ± 0.041	3.155AsnGlu: 3.155 ± 0.049	2.679AsnPhe: 2.679 ± 0.048	4.116AsnGly: 4.116 ± 0.07	0.999AsnHis: 0.999 ± 0.028	4.27AsnIle: 4.27 ± 0.062	3.501AsnLys: 3.501 ± 0.053	5.134AsnLeu: 5.134 ± 0.067	1.274AsnMet: 1.274 ± 0.023	3.362AsnAsn: 3.362 ± 0.059	2.791AsnPro: 2.791 ± 0.049	2.117AsnGln: 2.117 ± 0.036	2.6AsnArg: 2.6 ± 0.049	3.452AsnSer: 3.452 ± 0.05	3.537AsnThr: 3.537 ± 0.058	3.392AsnVal: 3.392 ± 0.051	0.797AsnTrp: 0.797 ± 0.022	2.677AsnTyr: 2.677 ± 0.048	0.0AsnXaa: 0.0 ± 0.0
Pro	2.592ProAla: 2.592 ± 0.064	0.209ProCys: 0.209 ± 0.013	2.326ProAsp: 2.326 ± 0.036	2.609ProGlu: 2.609 ± 0.041	1.903ProPhe: 1.903 ± 0.035	2.319ProGly: 2.319 ± 0.039	0.778ProHis: 0.778 ± 0.024	2.677ProIle: 2.677 ± 0.044	1.993ProLys: 1.993 ± 0.038	3.41ProLeu: 3.41 ± 0.049	0.728ProMet: 0.728 ± 0.022	2.139ProAsn: 2.139 ± 0.037	0.925ProPro: 0.925 ± 0.025	1.349ProGln: 1.349 ± 0.03	1.22ProArg: 1.22 ± 0.031	2.502ProSer: 2.502 ± 0.041	2.264ProThr: 2.264 ± 0.039	2.529ProVal: 2.529 ± 0.041	0.439ProTrp: 0.439 ± 0.016	1.647ProTyr: 1.647 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	2.519GlnAla: 2.519 ± 0.043	0.17GlnCys: 0.17 ± 0.011	1.94GlnAsp: 1.94 ± 0.032	2.405GlnGlu: 2.405 ± 0.046	1.673GlnPhe: 1.673 ± 0.032	2.185GlnGly: 2.185 ± 0.04	0.957GlnHis: 0.957 ± 0.022	2.72GlnIle: 2.72 ± 0.045	2.42GlnLys: 2.42 ± 0.041	3.895GlnLeu: 3.895 ± 0.053	0.839GlnMet: 0.839 ± 0.022	2.104GlnAsn: 2.104 ± 0.042	1.275GlnPro: 1.275 ± 0.031	1.948GlnGln: 1.948 ± 0.039	1.727GlnArg: 1.727 ± 0.035	2.275GlnSer: 2.275 ± 0.041	2.062GlnThr: 2.062 ± 0.036	2.4GlnVal: 2.4 ± 0.041	0.427GlnTrp: 0.427 ± 0.018	1.699GlnTyr: 1.699 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.651ArgAla: 2.651 ± 0.04	0.229ArgCys: 0.229 ± 0.013	2.284ArgAsp: 2.284 ± 0.039	2.587ArgGlu: 2.587 ± 0.045	2.214ArgPhe: 2.214 ± 0.037	2.554ArgGly: 2.554 ± 0.05	0.778ArgHis: 0.778 ± 0.022	3.38ArgIle: 3.38 ± 0.047	2.863ArgLys: 2.863 ± 0.05	4.179ArgLeu: 4.179 ± 0.056	1.097ArgMet: 1.097 ± 0.028	2.567ArgAsn: 2.567 ± 0.043	1.466ArgPro: 1.466 ± 0.031	1.61ArgGln: 1.61 ± 0.033	1.866ArgArg: 1.866 ± 0.042	2.529ArgSer: 2.529 ± 0.048	2.351ArgThr: 2.351 ± 0.041	2.647ArgVal: 2.647 ± 0.042	0.658ArgTrp: 0.658 ± 0.018	2.239ArgTyr: 2.239 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	4.561SerAla: 4.561 ± 0.049	0.625SerCys: 0.625 ± 0.022	3.506SerAsp: 3.506 ± 0.048	3.43SerGlu: 3.43 ± 0.046	3.715SerPhe: 3.715 ± 0.056	4.86SerGly: 4.86 ± 0.065	1.153SerHis: 1.153 ± 0.028	4.884SerIle: 4.884 ± 0.054	3.815SerLys: 3.815 ± 0.052	6.31SerLeu: 6.31 ± 0.06	1.342SerMet: 1.342 ± 0.024	3.577SerAsn: 3.577 ± 0.049	2.402SerPro: 2.402 ± 0.046	2.088SerGln: 2.088 ± 0.031	2.62SerArg: 2.62 ± 0.04	4.718SerSer: 4.718 ± 0.06	3.898SerThr: 3.898 ± 0.053	4.192SerVal: 4.192 ± 0.05	0.857SerTrp: 0.857 ± 0.025	3.069SerTyr: 3.069 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	4.304ThrAla: 4.304 ± 0.059	0.317ThrCys: 0.317 ± 0.015	3.341ThrAsp: 3.341 ± 0.047	3.129ThrGlu: 3.129 ± 0.043	2.804ThrPhe: 2.804 ± 0.048	4.501ThrGly: 4.501 ± 0.066	1.043ThrHis: 1.043 ± 0.027	4.208ThrIle: 4.208 ± 0.064	3.231ThrLys: 3.231 ± 0.047	5.493ThrLeu: 5.493 ± 0.077	1.001ThrMet: 1.001 ± 0.024	3.0ThrAsn: 3.0 ± 0.05	2.432ThrPro: 2.432 ± 0.049	1.919ThrGln: 1.919 ± 0.034	1.991ThrArg: 1.991 ± 0.036	3.741ThrSer: 3.741 ± 0.051	3.425ThrThr: 3.425 ± 0.062	4.029ThrVal: 4.029 ± 0.063	0.694ThrTrp: 0.694 ± 0.021	2.617ThrTyr: 2.617 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	4.447ValAla: 4.447 ± 0.066	0.481ValCys: 0.481 ± 0.018	3.969ValAsp: 3.969 ± 0.054	3.748ValGlu: 3.748 ± 0.047	3.168ValPhe: 3.168 ± 0.051	4.274ValGly: 4.274 ± 0.061	1.15ValHis: 1.15 ± 0.027	4.392ValIle: 4.392 ± 0.059	3.873ValLys: 3.873 ± 0.055	6.205ValLeu: 6.205 ± 0.067	1.324ValMet: 1.324 ± 0.029	3.698ValAsn: 3.698 ± 0.048	2.373ValPro: 2.373 ± 0.04	2.265ValGln: 2.265 ± 0.038	2.714ValArg: 2.714 ± 0.048	4.556ValSer: 4.556 ± 0.052	3.584ValThr: 3.584 ± 0.058	4.469ValVal: 4.469 ± 0.058	0.731ValTrp: 0.731 ± 0.022	2.589ValTyr: 2.589 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.787TrpAla: 0.787 ± 0.025	0.12TrpCys: 0.12 ± 0.008	0.721TrpAsp: 0.721 ± 0.023	0.755TrpGlu: 0.755 ± 0.022	0.553TrpPhe: 0.553 ± 0.019	0.929TrpGly: 0.929 ± 0.029	0.264TrpHis: 0.264 ± 0.012	0.882TrpIle: 0.882 ± 0.024	0.899TrpLys: 0.899 ± 0.027	1.105TrpLeu: 1.105 ± 0.029	0.361TrpMet: 0.361 ± 0.016	0.815TrpAsn: 0.815 ± 0.025	0.367TrpPro: 0.367 ± 0.019	0.552TrpGln: 0.552 ± 0.019	0.56TrpArg: 0.56 ± 0.02	0.807TrpSer: 0.807 ± 0.023	0.736TrpThr: 0.736 ± 0.02	0.676TrpVal: 0.676 ± 0.021	0.196TrpTrp: 0.196 ± 0.013	0.513TrpTyr: 0.513 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.024TyrAla: 3.024 ± 0.05	0.321TyrCys: 0.321 ± 0.016	2.543TyrAsp: 2.543 ± 0.052	2.275TyrGlu: 2.275 ± 0.037	2.288TyrPhe: 2.288 ± 0.043	3.077TyrGly: 3.077 ± 0.053	0.991TyrHis: 0.991 ± 0.027	2.769TyrIle: 2.769 ± 0.045	2.524TyrLys: 2.524 ± 0.04	4.054TyrLeu: 4.054 ± 0.057	0.905TyrMet: 0.905 ± 0.025	2.646TyrAsn: 2.646 ± 0.046	1.805TyrPro: 1.805 ± 0.034	1.745TyrGln: 1.745 ± 0.033	2.118TyrArg: 2.118 ± 0.041	2.784TyrSer: 2.784 ± 0.05	2.697TyrThr: 2.697 ± 0.042	2.451TyrVal: 2.451 ± 0.042	0.586TyrTrp: 0.586 ± 0.019	2.107TyrTyr: 2.107 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4341 proteins (1597812 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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