Schistosoma bovis (Blood fluke)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda; Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma

Average proteome isoelectric point is 6.71

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 11348 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A430QAF8|A0A430QAF8_SCHBO Uncharacterized protein OS=Schistosoma bovis OX=6184 GN=DC041_0008493 PE=4 SV=1
MM1 pKa = 7.06VADD4 pKa = 4.44GEE6 pKa = 4.4YY7 pKa = 10.75SDD9 pKa = 4.92VHH11 pKa = 6.37FLQSNISLYY20 pKa = 10.55EE21 pKa = 4.18DD22 pKa = 3.41SSLIDD27 pKa = 3.29TGTLKK32 pKa = 10.38ISEE35 pKa = 4.6EE36 pKa = 4.26CFTWEE41 pKa = 4.09GTSKK45 pKa = 10.53QFFIPYY51 pKa = 9.7SQITLHH57 pKa = 6.86AIARR61 pKa = 11.84NTVDD65 pKa = 3.17QTGDD69 pKa = 3.16HH70 pKa = 7.06PNNLFPHH77 pKa = 6.06PHH79 pKa = 6.59LLVMIDD85 pKa = 4.32GDD87 pKa = 4.68RR88 pKa = 11.84VWDD91 pKa = 4.14SNNTDD96 pKa = 3.49NLSDD100 pKa = 3.46TKK102 pKa = 11.04SQNEE106 pKa = 3.86QDD108 pKa = 3.7GMQIDD113 pKa = 4.34AEE115 pKa = 4.44GSDD118 pKa = 3.93EE119 pKa = 4.19EE120 pKa = 5.82KK121 pKa = 10.7EE122 pKa = 4.91DD123 pKa = 3.87SDD125 pKa = 4.48SDD127 pKa = 4.14RR128 pKa = 11.84APDD131 pKa = 3.96CPGSTSVLRR140 pKa = 11.84LVPQDD145 pKa = 3.53SAQLEE150 pKa = 4.28DD151 pKa = 4.11MYY153 pKa = 11.42KK154 pKa = 10.83ALADD158 pKa = 3.97CQALNPDD165 pKa = 4.39PEE167 pKa = 6.4DD168 pKa = 4.45DD169 pKa = 3.82NSDD172 pKa = 3.68FEE174 pKa = 5.68GFAEE178 pKa = 4.51DD179 pKa = 6.01DD180 pKa = 3.7EE181 pKa = 5.53YY182 pKa = 11.38EE183 pKa = 4.18INNQGMEE190 pKa = 4.51FEE192 pKa = 4.33NHH194 pKa = 5.6TNSEE198 pKa = 4.19FYY200 pKa = 10.76YY201 pKa = 11.02

Molecular weight: 22.7 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A430QB95|A0A430QB95_SCHBO Mitochondrial import inner membrane translocase subunit TIM22 OS=Schistosoma bovis OX=6184 GN=DC041_0010217 PE=3 SV=1
MM1 pKa = 7.77VDD3 pKa = 4.39DD4 pKa = 6.31RR5 pKa = 11.84LDD7 pKa = 3.61TLQKK11 pKa = 10.24EE12 pKa = 4.31INILCRR18 pKa = 11.84KK19 pKa = 8.11LTEE22 pKa = 3.73LTQRR26 pKa = 11.84EE27 pKa = 4.23KK28 pKa = 10.76PRR30 pKa = 11.84RR31 pKa = 11.84SSRR34 pKa = 11.84DD35 pKa = 2.82RR36 pKa = 11.84SRR38 pKa = 11.84EE39 pKa = 3.68RR40 pKa = 11.84TRR42 pKa = 11.84STSRR46 pKa = 11.84RR47 pKa = 11.84RR48 pKa = 11.84TTPAICWYY56 pKa = 9.42HH57 pKa = 7.18QMFGYY62 pKa = 10.08RR63 pKa = 11.84ARR65 pKa = 11.84KK66 pKa = 8.9CLQPCRR72 pKa = 11.84FNRR75 pKa = 11.84ASNRR79 pKa = 11.84YY80 pKa = 8.12PRR82 pKa = 11.84VSMATASTHH91 pKa = 6.06IMPEE95 pKa = 3.76NSRR98 pKa = 11.84LFYY101 pKa = 10.75IQDD104 pKa = 3.51RR105 pKa = 11.84TTGAQFLVDD114 pKa = 3.85TGAEE118 pKa = 3.86ISVVPPFNEE127 pKa = 3.38EE128 pKa = 3.7RR129 pKa = 11.84KK130 pKa = 10.31NINPSLVLRR139 pKa = 11.84AANKK143 pKa = 10.34SDD145 pKa = 2.25IKK147 pKa = 10.29TYY149 pKa = 10.32GKK151 pKa = 10.09RR152 pKa = 11.84QLSLDD157 pKa = 3.98FGRR160 pKa = 11.84GASYY164 pKa = 10.54RR165 pKa = 11.84WNFVIADD172 pKa = 3.47VSMPIIGIDD181 pKa = 3.48FLCNFDD187 pKa = 4.92LLVDD191 pKa = 4.0SRR193 pKa = 11.84RR194 pKa = 11.84HH195 pKa = 4.93RR196 pKa = 11.84LINGSQTTSIRR207 pKa = 11.84GG208 pKa = 3.33

Molecular weight: 24.22 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

11348

0

11348

5570637

30

7935

490.9

55.49

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.457 ± 0.024

2.117 ± 0.013

5.314 ± 0.018

5.481 ± 0.028

3.846 ± 0.016

4.312 ± 0.029

2.957 ± 0.014

6.705 ± 0.023

5.576 ± 0.025

9.697 ± 0.032

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.963 ± 0.008

7.455 ± 0.034

4.606 ± 0.022

4.347 ± 0.016

4.774 ± 0.019

10.375 ± 0.038

6.442 ± 0.025

5.261 ± 0.018

0.962 ± 0.008

3.338 ± 0.013
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski