Oryctolagus cuniculus (Rabbit)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria;

Average proteome isoelectric point is 6.85

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 41549 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|G1T9X1|G1T9X1_RABIT VWFA domain-containing protein OS=Oryctolagus cuniculus OX=9986 PE=3 SV=3
MM1 pKa = 7.44GGDD4 pKa = 3.55AGDD7 pKa = 4.59GEE9 pKa = 5.23LGPATGGLGPGQATFATADD28 pKa = 3.42PSGPEE33 pKa = 4.06TEE35 pKa = 5.46AEE37 pKa = 4.15TATDD41 pKa = 3.73RR42 pKa = 11.84LASGAQSVAPEE53 pKa = 4.13VPAQGEE59 pKa = 4.59GSHH62 pKa = 6.78SEE64 pKa = 4.16EE65 pKa = 4.17EE66 pKa = 4.34GLAGDD71 pKa = 4.36EE72 pKa = 4.51EE73 pKa = 4.7EE74 pKa = 5.4SDD76 pKa = 4.2GEE78 pKa = 4.08PTAWEE83 pKa = 4.18VPEE86 pKa = 5.76GRR88 pKa = 11.84RR89 pKa = 11.84CWPTEE94 pKa = 3.63HH95 pKa = 7.04SAEE98 pKa = 4.26LCSEE102 pKa = 4.04DD103 pKa = 4.33WDD105 pKa = 5.09LEE107 pKa = 4.24LQAEE111 pKa = 4.17QGNPYY116 pKa = 10.49DD117 pKa = 4.61ADD119 pKa = 3.87DD120 pKa = 4.07VQGSICQEE128 pKa = 3.75VKK130 pKa = 10.4PWVCCAARR138 pKa = 11.84GDD140 pKa = 4.17MIYY143 pKa = 10.69DD144 pKa = 4.27PSWHH148 pKa = 6.9HH149 pKa = 6.75PPPLIPHH156 pKa = 5.6YY157 pKa = 10.76SKK159 pKa = 10.49MVFEE163 pKa = 5.05TGQFDD168 pKa = 4.21DD169 pKa = 6.01AEE171 pKa = 4.35DD172 pKa = 3.31

Molecular weight: 18.22 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A5F9C283|A0A5F9C283_RABIT T-box transcription factor 6 OS=Oryctolagus cuniculus OX=9986 GN=TBX6 PE=4 SV=1
MM1 pKa = 7.1RR2 pKa = 11.84AKK4 pKa = 9.12WRR6 pKa = 11.84KK7 pKa = 9.1KK8 pKa = 9.32RR9 pKa = 11.84MRR11 pKa = 11.84RR12 pKa = 11.84LKK14 pKa = 10.08RR15 pKa = 11.84KK16 pKa = 8.21RR17 pKa = 11.84RR18 pKa = 11.84KK19 pKa = 8.46MRR21 pKa = 11.84QRR23 pKa = 11.84SKK25 pKa = 11.41

Molecular weight: 3.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

21193

20356

41549

24883876

6

8708

598.9

66.7

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.127 ± 0.013

2.224 ± 0.01

4.79 ± 0.007

7.032 ± 0.014

3.623 ± 0.01

6.511 ± 0.016

2.577 ± 0.006

4.409 ± 0.012

5.785 ± 0.013

9.895 ± 0.015

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.111 ± 0.005

3.613 ± 0.008

6.269 ± 0.017

4.747 ± 0.01

5.78 ± 0.012

8.291 ± 0.015

5.278 ± 0.008

6.03 ± 0.011

1.245 ± 0.004

2.615 ± 0.007
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski