Amino acid dipepetide frequency for Hubei sobemo-like virus 30

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.302AlaAla: 5.302 ± 3.132
1.06AlaCys: 1.06 ± 0.626
1.06AlaAsp: 1.06 ± 0.626
4.242AlaGlu: 4.242 ± 0.911
3.181AlaPhe: 3.181 ± 1.309
5.302AlaGly: 5.302 ± 1.537
1.06AlaHis: 1.06 ± 0.968
4.242AlaIle: 4.242 ± 0.911
3.181AlaLys: 3.181 ± 0.285
4.242AlaLeu: 4.242 ± 0.683
3.181AlaMet: 3.181 ± 1.309
4.242AlaAsn: 4.242 ± 0.683
2.121AlaPro: 2.121 ± 1.253
2.121AlaGln: 2.121 ± 0.341
4.242AlaArg: 4.242 ± 2.505
2.121AlaSer: 2.121 ± 1.253
4.242AlaThr: 4.242 ± 0.911
2.121AlaVal: 2.121 ± 1.253
0.0AlaTrp: 0.0 ± 0.0
1.06AlaTyr: 1.06 ± 0.626
0.0AlaXaa: 0.0 ± 0.0
Cys
2.121CysAla: 2.121 ± 1.253
1.06CysCys: 1.06 ± 0.626
0.0CysAsp: 0.0 ± 0.0
1.06CysGlu: 1.06 ± 0.626
2.121CysPhe: 2.121 ± 0.341
1.06CysGly: 1.06 ± 0.626
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.121CysLys: 2.121 ± 0.341
1.06CysLeu: 1.06 ± 0.968
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.121CysPro: 2.121 ± 1.253
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.121CysSer: 2.121 ± 1.253
0.0CysThr: 0.0 ± 0.0
1.06CysVal: 1.06 ± 0.968
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.121AspAla: 2.121 ± 1.253
1.06AspCys: 1.06 ± 0.626
4.242AspAsp: 4.242 ± 2.277
4.242AspGlu: 4.242 ± 0.911
4.242AspPhe: 4.242 ± 0.911
5.302AspGly: 5.302 ± 0.057
2.121AspHis: 2.121 ± 1.936
3.181AspIle: 3.181 ± 0.285
4.242AspLys: 4.242 ± 0.911
5.302AspLeu: 5.302 ± 1.651
3.181AspMet: 3.181 ± 2.903
1.06AspAsn: 1.06 ± 0.968
2.121AspPro: 2.121 ± 1.936
1.06AspGln: 1.06 ± 0.968
1.06AspArg: 1.06 ± 0.968
2.121AspSer: 2.121 ± 0.341
2.121AspThr: 2.121 ± 0.341
4.242AspVal: 4.242 ± 2.277
4.242AspTrp: 4.242 ± 2.277
1.06AspTyr: 1.06 ± 0.626
0.0AspXaa: 0.0 ± 0.0
Glu
4.242GluAla: 4.242 ± 0.911
1.06GluCys: 1.06 ± 0.626
1.06GluAsp: 1.06 ± 0.626
1.06GluGlu: 1.06 ± 0.968
2.121GluPhe: 2.121 ± 0.341
3.181GluGly: 3.181 ± 0.285
0.0GluHis: 0.0 ± 0.0
3.181GluIle: 3.181 ± 1.879
3.181GluLys: 3.181 ± 0.285
4.242GluLeu: 4.242 ± 0.911
2.121GluMet: 2.121 ± 1.253
2.121GluAsn: 2.121 ± 0.341
5.302GluPro: 5.302 ± 3.245
2.121GluGln: 2.121 ± 0.341
2.121GluArg: 2.121 ± 0.341
7.423GluSer: 7.423 ± 2.79
1.06GluThr: 1.06 ± 0.626
3.181GluVal: 3.181 ± 0.285
2.121GluTrp: 2.121 ± 1.936
1.06GluTyr: 1.06 ± 0.626
0.0GluXaa: 0.0 ± 0.0
Phe
3.181PheAla: 3.181 ± 1.309
1.06PheCys: 1.06 ± 0.626
6.363PheAsp: 6.363 ± 4.213
2.121PheGlu: 2.121 ± 1.936
0.0PhePhe: 0.0 ± 0.0
2.121PheGly: 2.121 ± 1.253
1.06PheHis: 1.06 ± 0.626
1.06PheIle: 1.06 ± 0.968
0.0PheLys: 0.0 ± 0.0
6.363PheLeu: 6.363 ± 2.164
1.06PheMet: 1.06 ± 0.968
3.181PheAsn: 3.181 ± 0.285
0.0PhePro: 0.0 ± 0.0
2.121PheGln: 2.121 ± 1.253
2.121PheArg: 2.121 ± 1.253
2.121PheSer: 2.121 ± 1.936
2.121PheThr: 2.121 ± 0.341
4.242PheVal: 4.242 ± 0.683
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.302GlyAla: 5.302 ± 1.537
1.06GlyCys: 1.06 ± 0.968
3.181GlyAsp: 3.181 ± 0.285
1.06GlyGlu: 1.06 ± 0.626
1.06GlyPhe: 1.06 ± 0.626
2.121GlyGly: 2.121 ± 1.936
2.121GlyHis: 2.121 ± 0.341
9.544GlyIle: 9.544 ± 0.74
6.363GlyLys: 6.363 ± 3.758
3.181GlyLeu: 3.181 ± 0.285
2.121GlyMet: 2.121 ± 0.341
0.0GlyAsn: 0.0 ± 0.0
3.181GlyPro: 3.181 ± 1.879
1.06GlyGln: 1.06 ± 0.626
6.363GlyArg: 6.363 ± 2.164
3.181GlySer: 3.181 ± 1.879
0.0GlyThr: 0.0 ± 0.0
3.181GlyVal: 3.181 ± 0.285
3.181GlyTrp: 3.181 ± 1.309
2.121GlyTyr: 2.121 ± 0.341
0.0GlyXaa: 0.0 ± 0.0
His
1.06HisAla: 1.06 ± 0.626
0.0HisCys: 0.0 ± 0.0
1.06HisAsp: 1.06 ± 0.968
1.06HisGlu: 1.06 ± 0.968
2.121HisPhe: 2.121 ± 0.341
0.0HisGly: 0.0 ± 0.0
1.06HisHis: 1.06 ± 0.626
2.121HisIle: 2.121 ± 1.253
1.06HisLys: 1.06 ± 0.626
1.06HisLeu: 1.06 ± 0.968
2.121HisMet: 2.121 ± 1.936
0.0HisAsn: 0.0 ± 0.0
1.06HisPro: 1.06 ± 0.626
0.0HisGln: 0.0 ± 0.0
2.121HisArg: 2.121 ± 1.936
1.06HisSer: 1.06 ± 0.968
1.06HisThr: 1.06 ± 0.626
3.181HisVal: 3.181 ± 0.285
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.121IleAla: 2.121 ± 1.253
0.0IleCys: 0.0 ± 0.0
6.363IleAsp: 6.363 ± 0.57
4.242IleGlu: 4.242 ± 0.683
3.181IlePhe: 3.181 ± 1.309
2.121IleGly: 2.121 ± 0.341
2.121IleHis: 2.121 ± 0.341
2.121IleIle: 2.121 ± 1.936
2.121IleLys: 2.121 ± 0.341
5.302IleLeu: 5.302 ± 0.057
1.06IleMet: 1.06 ± 0.968
2.121IleAsn: 2.121 ± 0.341
4.242IlePro: 4.242 ± 0.911
3.181IleGln: 3.181 ± 0.285
7.423IleArg: 7.423 ± 1.992
4.242IleSer: 4.242 ± 0.911
4.242IleThr: 4.242 ± 0.683
5.302IleVal: 5.302 ± 1.651
1.06IleTrp: 1.06 ± 0.626
1.06IleTyr: 1.06 ± 0.968
0.0IleXaa: 0.0 ± 0.0
Lys
1.06LysAla: 1.06 ± 0.626
0.0LysCys: 0.0 ± 0.0
4.242LysAsp: 4.242 ± 0.911
3.181LysGlu: 3.181 ± 1.879
2.121LysPhe: 2.121 ± 0.341
3.181LysGly: 3.181 ± 1.879
5.302LysHis: 5.302 ± 0.057
3.181LysIle: 3.181 ± 1.309
5.302LysLys: 5.302 ± 1.537
6.363LysLeu: 6.363 ± 1.024
0.0LysMet: 0.0 ± 0.0
6.363LysAsn: 6.363 ± 1.024
2.121LysPro: 2.121 ± 0.341
4.242LysGln: 4.242 ± 2.277
1.06LysArg: 1.06 ± 0.626
6.363LysSer: 6.363 ± 0.57
3.181LysThr: 3.181 ± 1.879
4.242LysVal: 4.242 ± 2.505
1.06LysTrp: 1.06 ± 0.968
2.121LysTyr: 2.121 ± 0.341
0.0LysXaa: 0.0 ± 0.0
Leu
2.121LeuAla: 2.121 ± 0.341
5.302LeuCys: 5.302 ± 1.537
5.302LeuAsp: 5.302 ± 3.245
6.363LeuGlu: 6.363 ± 0.57
6.363LeuPhe: 6.363 ± 4.213
4.242LeuGly: 4.242 ± 0.911
2.121LeuHis: 2.121 ± 1.936
4.242LeuIle: 4.242 ± 0.683
5.302LeuLys: 5.302 ± 0.057
9.544LeuLeu: 9.544 ± 5.522
0.0LeuMet: 0.0 ± 0.0
3.181LeuAsn: 3.181 ± 1.879
3.181LeuPro: 3.181 ± 0.285
1.06LeuGln: 1.06 ± 0.968
6.363LeuArg: 6.363 ± 2.619
6.363LeuSer: 6.363 ± 2.619
3.181LeuThr: 3.181 ± 1.879
8.484LeuVal: 8.484 ± 5.01
4.242LeuTrp: 4.242 ± 0.683
3.181LeuTyr: 3.181 ± 1.309
0.0LeuXaa: 0.0 ± 0.0
Met
1.06MetAla: 1.06 ± 0.968
0.0MetCys: 0.0 ± 0.0
5.302MetAsp: 5.302 ± 1.537
0.0MetGlu: 0.0 ± 0.0
3.181MetPhe: 3.181 ± 0.285
2.121MetGly: 2.121 ± 0.341
0.0MetHis: 0.0 ± 0.0
3.181MetIle: 3.181 ± 0.285
2.121MetLys: 2.121 ± 1.936
1.06MetLeu: 1.06 ± 0.968
1.06MetMet: 1.06 ± 0.397
1.06MetAsn: 1.06 ± 0.968
1.06MetPro: 1.06 ± 0.968
1.06MetGln: 1.06 ± 0.968
1.06MetArg: 1.06 ± 0.968
4.242MetSer: 4.242 ± 0.683
1.06MetThr: 1.06 ± 0.626
1.06MetVal: 1.06 ± 0.626
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.06AsnAla: 1.06 ± 0.626
1.06AsnCys: 1.06 ± 0.626
2.121AsnAsp: 2.121 ± 1.936
1.06AsnGlu: 1.06 ± 0.626
1.06AsnPhe: 1.06 ± 0.626
5.302AsnGly: 5.302 ± 0.057
0.0AsnHis: 0.0 ± 0.0
2.121AsnIle: 2.121 ± 1.253
1.06AsnLys: 1.06 ± 0.968
8.484AsnLeu: 8.484 ± 2.96
2.121AsnMet: 2.121 ± 1.012
2.121AsnAsn: 2.121 ± 1.253
1.06AsnPro: 1.06 ± 0.626
4.242AsnGln: 4.242 ± 2.505
2.121AsnArg: 2.121 ± 0.341
3.181AsnSer: 3.181 ± 1.309
3.181AsnThr: 3.181 ± 0.285
1.06AsnVal: 1.06 ± 0.968
1.06AsnTrp: 1.06 ± 0.626
1.06AsnTyr: 1.06 ± 0.626
0.0AsnXaa: 0.0 ± 0.0
Pro
5.302ProAla: 5.302 ± 0.057
0.0ProCys: 0.0 ± 0.0
2.121ProAsp: 2.121 ± 1.936
4.242ProGlu: 4.242 ± 0.911
2.121ProPhe: 2.121 ± 1.253
4.242ProGly: 4.242 ± 0.683
0.0ProHis: 0.0 ± 0.0
3.181ProIle: 3.181 ± 1.309
4.242ProLys: 4.242 ± 0.683
1.06ProLeu: 1.06 ± 0.968
1.06ProMet: 1.06 ± 0.626
2.121ProAsn: 2.121 ± 0.341
3.181ProPro: 3.181 ± 0.285
1.06ProGln: 1.06 ± 0.626
1.06ProArg: 1.06 ± 0.626
4.242ProSer: 4.242 ± 2.505
4.242ProThr: 4.242 ± 2.505
3.181ProVal: 3.181 ± 0.285
1.06ProTrp: 1.06 ± 0.968
1.06ProTyr: 1.06 ± 0.968
0.0ProXaa: 0.0 ± 0.0
Gln
1.06GlnAla: 1.06 ± 0.968
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.181GlnGlu: 3.181 ± 0.285
1.06GlnPhe: 1.06 ± 0.626
3.181GlnGly: 3.181 ± 1.879
1.06GlnHis: 1.06 ± 0.626
4.242GlnIle: 4.242 ± 2.277
4.242GlnLys: 4.242 ± 0.911
3.181GlnLeu: 3.181 ± 1.309
1.06GlnMet: 1.06 ± 0.968
2.121GlnAsn: 2.121 ± 1.253
2.121GlnPro: 2.121 ± 0.341
3.181GlnGln: 3.181 ± 1.879
1.06GlnArg: 1.06 ± 0.626
1.06GlnSer: 1.06 ± 0.626
2.121GlnThr: 2.121 ± 1.253
4.242GlnVal: 4.242 ± 0.683
0.0GlnTrp: 0.0 ± 0.0
1.06GlnTyr: 1.06 ± 0.626
0.0GlnXaa: 0.0 ± 0.0
Arg
2.121ArgAla: 2.121 ± 1.936
0.0ArgCys: 0.0 ± 0.0
2.121ArgAsp: 2.121 ± 1.936
3.181ArgGlu: 3.181 ± 1.309
1.06ArgPhe: 1.06 ± 0.968
1.06ArgGly: 1.06 ± 0.626
1.06ArgHis: 1.06 ± 0.626
3.181ArgIle: 3.181 ± 0.285
4.242ArgLys: 4.242 ± 0.911
7.423ArgLeu: 7.423 ± 0.398
0.0ArgMet: 0.0 ± 0.0
5.302ArgAsn: 5.302 ± 1.537
1.06ArgPro: 1.06 ± 0.968
0.0ArgGln: 0.0 ± 0.0
2.121ArgArg: 2.121 ± 1.253
7.423ArgSer: 7.423 ± 0.398
1.06ArgThr: 1.06 ± 0.626
3.181ArgVal: 3.181 ± 0.285
1.06ArgTrp: 1.06 ± 0.626
4.242ArgTyr: 4.242 ± 2.277
0.0ArgXaa: 0.0 ± 0.0
Ser
9.544SerAla: 9.544 ± 2.449
0.0SerCys: 0.0 ± 0.0
5.302SerAsp: 5.302 ± 0.057
3.181SerGlu: 3.181 ± 0.285
2.121SerPhe: 2.121 ± 0.341
6.363SerGly: 6.363 ± 0.57
0.0SerHis: 0.0 ± 0.0
3.181SerIle: 3.181 ± 2.903
9.544SerLys: 9.544 ± 2.449
5.302SerLeu: 5.302 ± 1.537
0.0SerMet: 0.0 ± 0.0
4.242SerAsn: 4.242 ± 0.911
5.302SerPro: 5.302 ± 1.537
5.302SerGln: 5.302 ± 0.057
3.181SerArg: 3.181 ± 0.285
10.604SerSer: 10.604 ± 0.113
4.242SerThr: 4.242 ± 2.505
5.302SerVal: 5.302 ± 1.651
1.06SerTrp: 1.06 ± 0.968
4.242SerTyr: 4.242 ± 0.683
0.0SerXaa: 0.0 ± 0.0
Thr
2.121ThrAla: 2.121 ± 1.253
0.0ThrCys: 0.0 ± 0.0
1.06ThrAsp: 1.06 ± 0.968
3.181ThrGlu: 3.181 ± 0.285
1.06ThrPhe: 1.06 ± 0.626
6.363ThrGly: 6.363 ± 0.57
0.0ThrHis: 0.0 ± 0.0
1.06ThrIle: 1.06 ± 0.968
2.121ThrLys: 2.121 ± 1.253
4.242ThrLeu: 4.242 ± 0.911
2.121ThrMet: 2.121 ± 1.253
1.06ThrAsn: 1.06 ± 0.626
5.302ThrPro: 5.302 ± 1.537
2.121ThrGln: 2.121 ± 1.253
0.0ThrArg: 0.0 ± 0.0
7.423ThrSer: 7.423 ± 1.196
4.242ThrThr: 4.242 ± 0.911
5.302ThrVal: 5.302 ± 1.537
1.06ThrTrp: 1.06 ± 0.626
2.121ThrTyr: 2.121 ± 1.253
0.0ThrXaa: 0.0 ± 0.0
Val
3.181ValAla: 3.181 ± 1.879
2.121ValCys: 2.121 ± 0.341
5.302ValAsp: 5.302 ± 0.057
5.302ValGlu: 5.302 ± 1.537
1.06ValPhe: 1.06 ± 0.626
2.121ValGly: 2.121 ± 1.253
1.06ValHis: 1.06 ± 0.626
6.363ValIle: 6.363 ± 0.57
3.181ValLys: 3.181 ± 2.903
8.484ValLeu: 8.484 ± 3.416
4.242ValMet: 4.242 ± 0.683
3.181ValAsn: 3.181 ± 1.309
2.121ValPro: 2.121 ± 0.341
3.181ValGln: 3.181 ± 1.879
3.181ValArg: 3.181 ± 0.285
6.363ValSer: 6.363 ± 2.164
3.181ValThr: 3.181 ± 1.309
6.363ValVal: 6.363 ± 0.57
0.0ValTrp: 0.0 ± 0.0
3.181ValTyr: 3.181 ± 2.903
0.0ValXaa: 0.0 ± 0.0
Trp
3.181TrpAla: 3.181 ± 0.285
0.0TrpCys: 0.0 ± 0.0
2.121TrpAsp: 2.121 ± 0.341
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.06TrpIle: 1.06 ± 0.626
1.06TrpLys: 1.06 ± 0.968
2.121TrpLeu: 2.121 ± 1.936
1.06TrpMet: 1.06 ± 0.968
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.06TrpArg: 1.06 ± 0.968
4.242TrpSer: 4.242 ± 0.683
4.242TrpThr: 4.242 ± 0.683
1.06TrpVal: 1.06 ± 0.968
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.06TyrAla: 1.06 ± 0.968
1.06TyrCys: 1.06 ± 0.968
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
1.06TyrPhe: 1.06 ± 0.968
0.0TyrGly: 0.0 ± 0.0
1.06TyrHis: 1.06 ± 0.968
3.181TyrIle: 3.181 ± 1.309
0.0TyrLys: 0.0 ± 0.0
2.121TyrLeu: 2.121 ± 1.936
2.121TyrMet: 2.121 ± 1.253
1.06TyrAsn: 1.06 ± 0.626
2.121TyrPro: 2.121 ± 0.341
2.121TyrGln: 2.121 ± 0.341
3.181TyrArg: 3.181 ± 2.903
2.121TyrSer: 2.121 ± 0.341
3.181TyrThr: 3.181 ± 1.879
3.181TyrVal: 3.181 ± 1.879
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (944 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski