Amino acid dipepetide frequency for Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.152AlaAla: 15.152 ± 0.154	0.909AlaCys: 0.909 ± 0.024	6.427AlaAsp: 6.427 ± 0.072	7.142AlaGlu: 7.142 ± 0.071	4.672AlaPhe: 4.672 ± 0.063	9.93AlaGly: 9.93 ± 0.091	1.98AlaHis: 1.98 ± 0.037	7.032AlaIle: 7.032 ± 0.075	4.442AlaLys: 4.442 ± 0.059	12.248AlaLeu: 12.248 ± 0.104	3.378AlaMet: 3.378 ± 0.046	3.052AlaAsn: 3.052 ± 0.047	4.454AlaPro: 4.454 ± 0.063	3.43AlaGln: 3.43 ± 0.05	7.216AlaArg: 7.216 ± 0.071	6.516AlaSer: 6.516 ± 0.072	5.732AlaThr: 5.732 ± 0.061	8.241AlaVal: 8.241 ± 0.079	1.257AlaTrp: 1.257 ± 0.026	2.515AlaTyr: 2.515 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.841CysAla: 0.841 ± 0.02	0.111CysCys: 0.111 ± 0.009	0.488CysAsp: 0.488 ± 0.021	0.439CysGlu: 0.439 ± 0.016	0.338CysPhe: 0.338 ± 0.013	0.864CysGly: 0.864 ± 0.02	0.23CysHis: 0.23 ± 0.012	0.39CysIle: 0.39 ± 0.015	0.214CysLys: 0.214 ± 0.012	0.818CysLeu: 0.818 ± 0.022	0.169CysMet: 0.169 ± 0.011	0.21CysAsn: 0.21 ± 0.011	0.384CysPro: 0.384 ± 0.017	0.235CysGln: 0.235 ± 0.014	0.559CysArg: 0.559 ± 0.022	0.471CysSer: 0.471 ± 0.02	0.363CysThr: 0.363 ± 0.016	0.552CysVal: 0.552 ± 0.018	0.11CysTrp: 0.11 ± 0.008	0.191CysTyr: 0.191 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.304AspAla: 6.304 ± 0.064	0.464AspCys: 0.464 ± 0.017	3.084AspAsp: 3.084 ± 0.049	3.452AspGlu: 3.452 ± 0.051	2.389AspPhe: 2.389 ± 0.042	4.968AspGly: 4.968 ± 0.062	1.231AspHis: 1.231 ± 0.029	3.787AspIle: 3.787 ± 0.055	1.97AspLys: 1.97 ± 0.04	5.488AspLeu: 5.488 ± 0.065	1.524AspMet: 1.524 ± 0.031	1.584AspAsn: 1.584 ± 0.029	2.994AspPro: 2.994 ± 0.049	1.602AspGln: 1.602 ± 0.031	3.87AspArg: 3.87 ± 0.057	2.087AspSer: 2.087 ± 0.039	2.488AspThr: 2.488 ± 0.038	4.166AspVal: 4.166 ± 0.051	0.888AspTrp: 0.888 ± 0.024	1.549AspTyr: 1.549 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	7.117GluAla: 7.117 ± 0.08	0.34GluCys: 0.34 ± 0.015	2.87GluAsp: 2.87 ± 0.043	3.566GluGlu: 3.566 ± 0.066	1.932GluPhe: 1.932 ± 0.032	4.185GluGly: 4.185 ± 0.047	1.158GluHis: 1.158 ± 0.028	3.778GluIle: 3.778 ± 0.052	3.286GluLys: 3.286 ± 0.054	5.227GluLeu: 5.227 ± 0.062	1.589GluMet: 1.589 ± 0.03	2.168GluAsn: 2.168 ± 0.041	2.556GluPro: 2.556 ± 0.048	2.084GluGln: 2.084 ± 0.037	4.69GluArg: 4.69 ± 0.06	2.351GluSer: 2.351 ± 0.039	3.911GluThr: 3.911 ± 0.046	3.596GluVal: 3.596 ± 0.053	0.71GluTrp: 0.71 ± 0.021	1.045GluTyr: 1.045 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.621PheAla: 4.621 ± 0.064	0.436PheCys: 0.436 ± 0.018	2.734PheAsp: 2.734 ± 0.042	2.293PheGlu: 2.293 ± 0.037	1.738PhePhe: 1.738 ± 0.041	3.763PheGly: 3.763 ± 0.053	0.842PheHis: 0.842 ± 0.022	2.099PheIle: 2.099 ± 0.036	1.219PheLys: 1.219 ± 0.028	3.775PheLeu: 3.775 ± 0.057	0.945PheMet: 0.945 ± 0.027	1.26PheAsn: 1.26 ± 0.024	1.705PhePro: 1.705 ± 0.031	1.161PheGln: 1.161 ± 0.026	2.374PheArg: 2.374 ± 0.038	2.928PheSer: 2.928 ± 0.046	2.056PheThr: 2.056 ± 0.04	2.996PheVal: 2.996 ± 0.049	0.564PheTrp: 0.564 ± 0.022	1.022PheTyr: 1.022 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	8.157GlyAla: 8.157 ± 0.086	0.795GlyCys: 0.795 ± 0.023	4.148GlyAsp: 4.148 ± 0.051	4.92GlyGlu: 4.92 ± 0.065	3.808GlyPhe: 3.808 ± 0.055	6.77GlyGly: 6.77 ± 0.095	1.836GlyHis: 1.836 ± 0.036	5.023GlyIle: 5.023 ± 0.061	3.91GlyLys: 3.91 ± 0.055	8.622GlyLeu: 8.622 ± 0.072	2.344GlyMet: 2.344 ± 0.035	2.523GlyAsn: 2.523 ± 0.041	2.978GlyPro: 2.978 ± 0.047	2.761GlyGln: 2.761 ± 0.041	5.489GlyArg: 5.489 ± 0.066	4.739GlySer: 4.739 ± 0.064	4.341GlyThr: 4.341 ± 0.063	5.948GlyVal: 5.948 ± 0.069	1.232GlyTrp: 1.232 ± 0.029	2.314GlyTyr: 2.314 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.158HisAla: 2.158 ± 0.038	0.208HisCys: 0.208 ± 0.011	1.284HisAsp: 1.284 ± 0.029	1.081HisGlu: 1.081 ± 0.025	0.922HisPhe: 0.922 ± 0.023	1.879HisGly: 1.879 ± 0.038	0.552HisHis: 0.552 ± 0.023	1.098HisIle: 1.098 ± 0.027	0.53HisLys: 0.53 ± 0.018	2.016HisLeu: 2.016 ± 0.034	0.533HisMet: 0.533 ± 0.02	0.52HisAsn: 0.52 ± 0.019	1.199HisPro: 1.199 ± 0.03	0.588HisGln: 0.588 ± 0.019	1.369HisArg: 1.369 ± 0.03	1.056HisSer: 1.056 ± 0.025	0.827HisThr: 0.827 ± 0.023	1.441HisVal: 1.441 ± 0.032	0.288HisTrp: 0.288 ± 0.014	0.546HisTyr: 0.546 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.757IleAla: 7.757 ± 0.088	0.57IleCys: 0.57 ± 0.02	3.867IleAsp: 3.867 ± 0.05	3.796IleGlu: 3.796 ± 0.049	2.169IlePhe: 2.169 ± 0.043	5.474IleGly: 5.474 ± 0.062	1.009IleHis: 1.009 ± 0.025	3.032IleIle: 3.032 ± 0.046	1.747IleLys: 1.747 ± 0.036	5.064IleLeu: 5.064 ± 0.058	1.246IleMet: 1.246 ± 0.028	1.732IleAsn: 1.732 ± 0.029	2.483IlePro: 2.483 ± 0.041	1.241IleGln: 1.241 ± 0.032	3.574IleArg: 3.574 ± 0.056	3.646IleSer: 3.646 ± 0.049	2.902IleThr: 2.902 ± 0.035	4.707IleVal: 4.707 ± 0.056	0.662IleTrp: 0.662 ± 0.023	1.293IleTyr: 1.293 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.908LysAla: 4.908 ± 0.069	0.178LysCys: 0.178 ± 0.01	2.071LysAsp: 2.071 ± 0.043	1.977LysGlu: 1.977 ± 0.039	1.135LysPhe: 1.135 ± 0.03	3.038LysGly: 3.038 ± 0.051	0.667LysHis: 0.667 ± 0.02	2.225LysIle: 2.225 ± 0.038	1.727LysLys: 1.727 ± 0.036	3.753LysLeu: 3.753 ± 0.051	0.971LysMet: 0.971 ± 0.024	1.281LysAsn: 1.281 ± 0.031	2.354LysPro: 2.354 ± 0.046	1.217LysGln: 1.217 ± 0.03	2.576LysArg: 2.576 ± 0.044	2.454LysSer: 2.454 ± 0.04	2.493LysThr: 2.493 ± 0.042	2.767LysVal: 2.767 ± 0.051	0.406LysTrp: 0.406 ± 0.017	0.724LysTyr: 0.724 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	12.099LeuAla: 12.099 ± 0.1	0.883LeuCys: 0.883 ± 0.023	5.605LeuAsp: 5.605 ± 0.063	5.382LeuGlu: 5.382 ± 0.057	3.87LeuPhe: 3.87 ± 0.054	7.632LeuGly: 7.632 ± 0.072	1.788LeuHis: 1.788 ± 0.039	5.307LeuIle: 5.307 ± 0.062	4.278LeuLys: 4.278 ± 0.055	9.35LeuLeu: 9.35 ± 0.101	2.417LeuMet: 2.417 ± 0.044	2.896LeuAsn: 2.896 ± 0.04	5.37LeuPro: 5.37 ± 0.059	2.832LeuGln: 2.832 ± 0.045	6.087LeuArg: 6.087 ± 0.062	7.416LeuSer: 7.416 ± 0.084	5.602LeuThr: 5.602 ± 0.076	7.175LeuVal: 7.175 ± 0.079	1.076LeuTrp: 1.076 ± 0.025	2.185LeuTyr: 2.185 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	3.068MetAla: 3.068 ± 0.044	0.145MetCys: 0.145 ± 0.009	1.197MetAsp: 1.197 ± 0.027	1.337MetGlu: 1.337 ± 0.025	0.748MetPhe: 0.748 ± 0.022	1.737MetGly: 1.737 ± 0.033	0.447MetHis: 0.447 ± 0.016	1.585MetIle: 1.585 ± 0.031	1.161MetLys: 1.161 ± 0.027	2.57MetLeu: 2.57 ± 0.04	0.727MetMet: 0.727 ± 0.019	0.905MetAsn: 0.905 ± 0.021	1.488MetPro: 1.488 ± 0.031	0.912MetGln: 0.912 ± 0.021	1.864MetArg: 1.864 ± 0.036	1.733MetSer: 1.733 ± 0.031	2.016MetThr: 2.016 ± 0.035	1.839MetVal: 1.839 ± 0.033	0.213MetTrp: 0.213 ± 0.013	0.311MetTyr: 0.311 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.491AsnAla: 3.491 ± 0.056	0.238AsnCys: 0.238 ± 0.013	1.635AsnAsp: 1.635 ± 0.039	1.467AsnGlu: 1.467 ± 0.029	1.224AsnPhe: 1.224 ± 0.025	2.812AsnGly: 2.812 ± 0.048	0.623AsnHis: 0.623 ± 0.017	1.74AsnIle: 1.74 ± 0.03	0.832AsnLys: 0.832 ± 0.024	2.884AsnLeu: 2.884 ± 0.042	0.752AsnMet: 0.752 ± 0.02	0.91AsnAsn: 0.91 ± 0.025	1.919AsnPro: 1.919 ± 0.036	0.85AsnGln: 0.85 ± 0.024	2.088AsnArg: 2.088 ± 0.037	1.551AsnSer: 1.551 ± 0.029	1.446AsnThr: 1.446 ± 0.029	2.169AsnVal: 2.169 ± 0.034	0.46AsnTrp: 0.46 ± 0.017	0.766AsnTyr: 0.766 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	5.483ProAla: 5.483 ± 0.07	0.291ProCys: 0.291 ± 0.014	3.314ProAsp: 3.314 ± 0.051	3.527ProGlu: 3.527 ± 0.047	2.039ProPhe: 2.039 ± 0.041	3.86ProGly: 3.86 ± 0.047	1.051ProHis: 1.051 ± 0.025	2.203ProIle: 2.203 ± 0.04	1.826ProLys: 1.826 ± 0.035	4.559ProLeu: 4.559 ± 0.06	1.146ProMet: 1.146 ± 0.028	1.262ProAsn: 1.262 ± 0.029	2.06ProPro: 2.06 ± 0.045	1.695ProGln: 1.695 ± 0.036	2.48ProArg: 2.48 ± 0.04	2.787ProSer: 2.787 ± 0.041	2.228ProThr: 2.228 ± 0.041	4.235ProVal: 4.235 ± 0.053	0.571ProTrp: 0.571 ± 0.021	1.207ProTyr: 1.207 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.613GlnAla: 3.613 ± 0.049	0.182GlnCys: 0.182 ± 0.012	1.395GlnAsp: 1.395 ± 0.03	1.6GlnGlu: 1.6 ± 0.035	1.104GlnPhe: 1.104 ± 0.028	2.219GlnGly: 2.219 ± 0.039	0.627GlnHis: 0.627 ± 0.018	1.956GlnIle: 1.956 ± 0.048	1.383GlnLys: 1.383 ± 0.033	2.867GlnLeu: 2.867 ± 0.04	0.922GlnMet: 0.922 ± 0.025	1.042GlnAsn: 1.042 ± 0.026	1.736GlnPro: 1.736 ± 0.039	1.409GlnGln: 1.409 ± 0.037	2.286GlnArg: 2.286 ± 0.045	1.994GlnSer: 1.994 ± 0.033	1.814GlnThr: 1.814 ± 0.028	2.097GlnVal: 2.097 ± 0.039	0.394GlnTrp: 0.394 ± 0.015	0.608GlnTyr: 0.608 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	6.468ArgAla: 6.468 ± 0.079	0.419ArgCys: 0.419 ± 0.016	3.792ArgAsp: 3.792 ± 0.052	3.894ArgGlu: 3.894 ± 0.056	2.998ArgPhe: 2.998 ± 0.042	4.251ArgGly: 4.251 ± 0.054	1.658ArgHis: 1.658 ± 0.029	4.147ArgIle: 4.147 ± 0.054	2.613ArgLys: 2.613 ± 0.048	7.148ArgLeu: 7.148 ± 0.077	1.803ArgMet: 1.803 ± 0.03	2.135ArgAsn: 2.135 ± 0.034	3.062ArgPro: 3.062 ± 0.043	2.67ArgGln: 2.67 ± 0.043	4.937ArgArg: 4.937 ± 0.059	3.716ArgSer: 3.716 ± 0.054	3.111ArgThr: 3.111 ± 0.049	4.26ArgVal: 4.26 ± 0.058	0.866ArgTrp: 0.866 ± 0.023	1.693ArgTyr: 1.693 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	6.396SerAla: 6.396 ± 0.079	0.456SerCys: 0.456 ± 0.019	3.136SerAsp: 3.136 ± 0.038	3.114SerGlu: 3.114 ± 0.047	2.756SerPhe: 2.756 ± 0.047	6.092SerGly: 6.092 ± 0.068	1.26SerHis: 1.26 ± 0.026	3.199SerIle: 3.199 ± 0.042	1.983SerLys: 1.983 ± 0.038	6.057SerLeu: 6.057 ± 0.068	1.496SerMet: 1.496 ± 0.029	1.654SerAsn: 1.654 ± 0.035	2.839SerPro: 2.839 ± 0.041	1.825SerGln: 1.825 ± 0.034	3.875SerArg: 3.875 ± 0.049	3.664SerSer: 3.664 ± 0.054	3.008SerThr: 3.008 ± 0.061	4.396SerVal: 4.396 ± 0.06	0.792SerTrp: 0.792 ± 0.023	1.459SerTyr: 1.459 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.069ThrAla: 6.069 ± 0.067	0.383ThrCys: 0.383 ± 0.016	2.875ThrAsp: 2.875 ± 0.045	2.779ThrGlu: 2.779 ± 0.042	2.11ThrPhe: 2.11 ± 0.04	5.007ThrGly: 5.007 ± 0.061	1.031ThrHis: 1.031 ± 0.026	3.305ThrIle: 3.305 ± 0.055	1.736ThrLys: 1.736 ± 0.033	5.728ThrLeu: 5.728 ± 0.065	1.282ThrMet: 1.282 ± 0.026	1.392ThrAsn: 1.392 ± 0.029	2.962ThrPro: 2.962 ± 0.047	1.452ThrGln: 1.452 ± 0.029	3.136ThrArg: 3.136 ± 0.045	3.131ThrSer: 3.131 ± 0.046	2.954ThrThr: 2.954 ± 0.05	4.587ThrVal: 4.587 ± 0.049	0.595ThrTrp: 0.595 ± 0.021	1.241ThrTyr: 1.241 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	8.542ValAla: 8.542 ± 0.076	0.609ValCys: 0.609 ± 0.02	3.944ValAsp: 3.944 ± 0.049	4.544ValGlu: 4.544 ± 0.059	2.982ValPhe: 2.982 ± 0.047	5.288ValGly: 5.288 ± 0.064	1.325ValHis: 1.325 ± 0.029	4.324ValIle: 4.324 ± 0.059	2.794ValLys: 2.794 ± 0.046	7.216ValLeu: 7.216 ± 0.078	1.925ValMet: 1.925 ± 0.038	2.148ValAsn: 2.148 ± 0.036	3.52ValPro: 3.52 ± 0.045	1.997ValGln: 1.997 ± 0.037	4.405ValArg: 4.405 ± 0.054	5.03ValSer: 5.03 ± 0.046	4.645ValThr: 4.645 ± 0.055	5.774ValVal: 5.774 ± 0.068	0.843ValTrp: 0.843 ± 0.025	1.53ValTyr: 1.53 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.107TrpAla: 1.107 ± 0.026	0.132TrpCys: 0.132 ± 0.01	0.597TrpAsp: 0.597 ± 0.021	0.53TrpGlu: 0.53 ± 0.018	0.583TrpPhe: 0.583 ± 0.02	0.785TrpGly: 0.785 ± 0.021	0.294TrpHis: 0.294 ± 0.015	0.655TrpIle: 0.655 ± 0.022	0.545TrpLys: 0.545 ± 0.019	1.536TrpLeu: 1.536 ± 0.035	0.334TrpMet: 0.334 ± 0.015	0.506TrpAsn: 0.506 ± 0.015	0.648TrpPro: 0.648 ± 0.02	0.578TrpGln: 0.578 ± 0.018	0.962TrpArg: 0.962 ± 0.027	0.818TrpSer: 0.818 ± 0.023	0.667TrpThr: 0.667 ± 0.019	0.736TrpVal: 0.736 ± 0.022	0.217TrpTrp: 0.217 ± 0.013	0.292TrpTyr: 0.292 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.369TyrAla: 2.369 ± 0.041	0.228TyrCys: 0.228 ± 0.011	1.424TyrAsp: 1.424 ± 0.031	1.318TyrGlu: 1.318 ± 0.03	1.011TyrPhe: 1.011 ± 0.026	2.109TyrGly: 2.109 ± 0.039	0.486TyrHis: 0.486 ± 0.015	1.088TyrIle: 1.088 ± 0.025	0.727TyrLys: 0.727 ± 0.023	2.325TyrLeu: 2.325 ± 0.04	0.499TyrMet: 0.499 ± 0.016	0.679TyrAsn: 0.679 ± 0.021	1.117TyrPro: 1.117 ± 0.029	0.71TyrGln: 0.71 ± 0.023	1.803TyrArg: 1.803 ± 0.035	1.371TyrSer: 1.371 ± 0.032	1.149TyrThr: 1.149 ± 0.03	1.701TyrVal: 1.701 ± 0.03	0.377TyrTrp: 0.377 ± 0.015	0.638TyrTyr: 0.638 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5344 proteins (1660809 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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