Amino acid dipepetide frequency for Acinetobacter phage SH-Ab 15599

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.941AlaAla: 4.941 ± 0.476
0.529AlaCys: 0.529 ± 0.103
3.999AlaAsp: 3.999 ± 0.282
4.505AlaGlu: 4.505 ± 0.386
2.62AlaPhe: 2.62 ± 0.25
4.091AlaGly: 4.091 ± 0.441
1.08AlaHis: 1.08 ± 0.164
4.688AlaIle: 4.688 ± 0.377
5.332AlaLys: 5.332 ± 0.318
5.263AlaLeu: 5.263 ± 0.441
1.655AlaMet: 1.655 ± 0.227
3.424AlaAsn: 3.424 ± 0.352
2.413AlaPro: 2.413 ± 0.268
2.459AlaGln: 2.459 ± 0.299
2.367AlaArg: 2.367 ± 0.219
4.252AlaSer: 4.252 ± 0.402
4.068AlaThr: 4.068 ± 0.347
3.976AlaVal: 3.976 ± 0.338
0.942AlaTrp: 0.942 ± 0.159
2.39AlaTyr: 2.39 ± 0.216
0.0AlaXaa: 0.0 ± 0.0
Cys
0.575CysAla: 0.575 ± 0.124
0.115CysCys: 0.115 ± 0.047
0.666CysAsp: 0.666 ± 0.137
0.758CysGlu: 0.758 ± 0.13
0.529CysPhe: 0.529 ± 0.106
0.712CysGly: 0.712 ± 0.146
0.391CysHis: 0.391 ± 0.095
0.827CysIle: 0.827 ± 0.125
0.919CysLys: 0.919 ± 0.156
0.988CysLeu: 0.988 ± 0.163
0.23CysMet: 0.23 ± 0.065
0.552CysAsn: 0.552 ± 0.112
0.46CysPro: 0.46 ± 0.096
0.391CysGln: 0.391 ± 0.078
0.437CysArg: 0.437 ± 0.119
0.666CysSer: 0.666 ± 0.128
0.46CysThr: 0.46 ± 0.084
0.781CysVal: 0.781 ± 0.134
0.184CysTrp: 0.184 ± 0.062
0.322CysTyr: 0.322 ± 0.096
0.0CysXaa: 0.0 ± 0.0
Asp
3.516AspAla: 3.516 ± 0.245
0.781AspCys: 0.781 ± 0.139
3.516AspAsp: 3.516 ± 0.248
4.551AspGlu: 4.551 ± 0.455
4.137AspPhe: 4.137 ± 0.341
4.137AspGly: 4.137 ± 0.277
1.103AspHis: 1.103 ± 0.157
4.757AspIle: 4.757 ± 0.331
3.792AspLys: 3.792 ± 0.328
5.355AspLeu: 5.355 ± 0.379
1.839AspMet: 1.839 ± 0.195
3.172AspAsn: 3.172 ± 0.234
2.666AspPro: 2.666 ± 0.247
2.206AspGln: 2.206 ± 0.243
2.183AspArg: 2.183 ± 0.204
4.16AspSer: 4.16 ± 0.287
3.539AspThr: 3.539 ± 0.323
4.298AspVal: 4.298 ± 0.296
0.735AspTrp: 0.735 ± 0.122
2.482AspTyr: 2.482 ± 0.242
0.0AspXaa: 0.0 ± 0.0
Glu
5.401GluAla: 5.401 ± 0.418
1.149GluCys: 1.149 ± 0.18
3.953GluAsp: 3.953 ± 0.316
3.769GluGlu: 3.769 ± 0.355
2.758GluPhe: 2.758 ± 0.216
3.93GluGly: 3.93 ± 0.275
1.402GluHis: 1.402 ± 0.159
5.171GluIle: 5.171 ± 0.333
4.137GluLys: 4.137 ± 0.397
5.815GluLeu: 5.815 ± 0.4
2.252GluMet: 2.252 ± 0.222
3.585GluAsn: 3.585 ± 0.246
1.678GluPro: 1.678 ± 0.2
2.942GluGln: 2.942 ± 0.325
3.677GluArg: 3.677 ± 0.343
3.815GluSer: 3.815 ± 0.29
4.137GluThr: 4.137 ± 0.286
4.16GluVal: 4.16 ± 0.357
0.85GluTrp: 0.85 ± 0.157
3.378GluTyr: 3.378 ± 0.295
0.0GluXaa: 0.0 ± 0.0
Phe
2.436PheAla: 2.436 ± 0.228
0.644PheCys: 0.644 ± 0.123
3.608PheAsp: 3.608 ± 0.306
3.103PheGlu: 3.103 ± 0.286
2.045PhePhe: 2.045 ± 0.199
2.85PheGly: 2.85 ± 0.23
0.781PheHis: 0.781 ± 0.119
2.896PheIle: 2.896 ± 0.276
4.068PheLys: 4.068 ± 0.297
3.355PheLeu: 3.355 ± 0.305
1.241PheMet: 1.241 ± 0.184
3.126PheAsn: 3.126 ± 0.336
1.379PhePro: 1.379 ± 0.196
1.816PheGln: 1.816 ± 0.195
1.999PheArg: 1.999 ± 0.18
3.218PheSer: 3.218 ± 0.26
2.436PheThr: 2.436 ± 0.227
3.103PheVal: 3.103 ± 0.267
0.529PheTrp: 0.529 ± 0.113
2.068PheTyr: 2.068 ± 0.206
0.0PheXaa: 0.0 ± 0.0
Gly
4.022GlyAla: 4.022 ± 0.418
0.575GlyCys: 0.575 ± 0.125
3.493GlyAsp: 3.493 ± 0.305
3.723GlyGlu: 3.723 ± 0.326
2.597GlyPhe: 2.597 ± 0.265
4.252GlyGly: 4.252 ± 0.554
1.356GlyHis: 1.356 ± 0.174
3.907GlyIle: 3.907 ± 0.264
4.757GlyLys: 4.757 ± 0.301
5.102GlyLeu: 5.102 ± 0.338
1.563GlyMet: 1.563 ± 0.256
3.172GlyAsn: 3.172 ± 0.393
0.827GlyPro: 0.827 ± 0.154
2.068GlyGln: 2.068 ± 0.201
2.528GlyArg: 2.528 ± 0.242
4.711GlySer: 4.711 ± 0.474
4.482GlyThr: 4.482 ± 0.478
4.275GlyVal: 4.275 ± 0.328
0.965GlyTrp: 0.965 ± 0.173
2.068GlyTyr: 2.068 ± 0.227
0.0GlyXaa: 0.0 ± 0.0
His
1.287HisAla: 1.287 ± 0.18
0.391HisCys: 0.391 ± 0.103
0.827HisAsp: 0.827 ± 0.161
1.034HisGlu: 1.034 ± 0.174
1.333HisPhe: 1.333 ± 0.184
1.011HisGly: 1.011 ± 0.164
0.207HisHis: 0.207 ± 0.066
1.471HisIle: 1.471 ± 0.173
1.241HisLys: 1.241 ± 0.154
1.609HisLeu: 1.609 ± 0.234
0.598HisMet: 0.598 ± 0.124
1.08HisAsn: 1.08 ± 0.141
0.85HisPro: 0.85 ± 0.128
0.414HisGln: 0.414 ± 0.082
0.598HisArg: 0.598 ± 0.109
1.31HisSer: 1.31 ± 0.171
0.988HisThr: 0.988 ± 0.13
1.517HisVal: 1.517 ± 0.17
0.207HisTrp: 0.207 ± 0.066
0.735HisTyr: 0.735 ± 0.133
0.0HisXaa: 0.0 ± 0.0
Ile
4.137IleAla: 4.137 ± 0.298
0.621IleCys: 0.621 ± 0.132
5.677IleAsp: 5.677 ± 0.399
5.631IleGlu: 5.631 ± 0.345
2.597IlePhe: 2.597 ± 0.241
3.677IleGly: 3.677 ± 0.29
1.264IleHis: 1.264 ± 0.175
4.528IleIle: 4.528 ± 0.363
5.171IleLys: 5.171 ± 0.386
5.079IleLeu: 5.079 ± 0.346
1.54IleMet: 1.54 ± 0.187
4.39IleAsn: 4.39 ± 0.31
2.528IlePro: 2.528 ± 0.268
2.712IleGln: 2.712 ± 0.28
2.666IleArg: 2.666 ± 0.25
4.803IleSer: 4.803 ± 0.319
3.976IleThr: 3.976 ± 0.356
5.378IleVal: 5.378 ± 0.37
0.529IleTrp: 0.529 ± 0.106
2.045IleTyr: 2.045 ± 0.209
0.0IleXaa: 0.0 ± 0.0
Lys
5.194LysAla: 5.194 ± 0.414
0.598LysCys: 0.598 ± 0.123
4.918LysAsp: 4.918 ± 0.335
5.056LysGlu: 5.056 ± 0.428
2.919LysPhe: 2.919 ± 0.225
3.907LysGly: 3.907 ± 0.295
1.563LysHis: 1.563 ± 0.214
4.62LysIle: 4.62 ± 0.305
4.091LysLys: 4.091 ± 0.365
5.585LysLeu: 5.585 ± 0.312
1.999LysMet: 1.999 ± 0.219
3.447LysAsn: 3.447 ± 0.254
2.919LysPro: 2.919 ± 0.255
3.355LysGln: 3.355 ± 0.256
3.401LysArg: 3.401 ± 0.258
4.137LysSer: 4.137 ± 0.304
4.459LysThr: 4.459 ± 0.335
5.148LysVal: 5.148 ± 0.386
0.919LysTrp: 0.919 ± 0.135
3.011LysTyr: 3.011 ± 0.282
0.0LysXaa: 0.0 ± 0.0
Leu
4.895LeuAla: 4.895 ± 0.326
0.621LeuCys: 0.621 ± 0.121
4.528LeuAsp: 4.528 ± 0.395
5.47LeuGlu: 5.47 ± 0.4
3.562LeuPhe: 3.562 ± 0.32
4.206LeuGly: 4.206 ± 0.382
1.586LeuHis: 1.586 ± 0.214
4.872LeuIle: 4.872 ± 0.318
6.872LeuLys: 6.872 ± 0.484
5.838LeuLeu: 5.838 ± 0.365
2.229LeuMet: 2.229 ± 0.209
5.102LeuAsn: 5.102 ± 0.361
3.126LeuPro: 3.126 ± 0.313
3.149LeuGln: 3.149 ± 0.323
3.401LeuArg: 3.401 ± 0.304
5.953LeuSer: 5.953 ± 0.367
4.551LeuThr: 4.551 ± 0.302
5.01LeuVal: 5.01 ± 0.387
0.621LeuTrp: 0.621 ± 0.119
3.447LeuTyr: 3.447 ± 0.34
0.0LeuXaa: 0.0 ± 0.0
Met
1.724MetAla: 1.724 ± 0.2
0.253MetCys: 0.253 ± 0.073
1.563MetAsp: 1.563 ± 0.212
1.517MetGlu: 1.517 ± 0.198
1.333MetPhe: 1.333 ± 0.191
1.356MetGly: 1.356 ± 0.172
0.437MetHis: 0.437 ± 0.103
1.747MetIle: 1.747 ± 0.201
2.16MetLys: 2.16 ± 0.268
1.977MetLeu: 1.977 ± 0.256
0.781MetMet: 0.781 ± 0.179
1.77MetAsn: 1.77 ± 0.208
0.781MetPro: 0.781 ± 0.117
0.644MetGln: 0.644 ± 0.127
0.942MetArg: 0.942 ± 0.135
2.39MetSer: 2.39 ± 0.235
1.517MetThr: 1.517 ± 0.202
1.632MetVal: 1.632 ± 0.178
0.184MetTrp: 0.184 ± 0.061
0.896MetTyr: 0.896 ± 0.146
0.0MetXaa: 0.0 ± 0.0
Asn
3.792AsnAla: 3.792 ± 0.295
0.735AsnCys: 0.735 ± 0.136
2.942AsnAsp: 2.942 ± 0.234
3.769AsnGlu: 3.769 ± 0.336
2.62AsnPhe: 2.62 ± 0.259
5.033AsnGly: 5.033 ± 0.422
0.942AsnHis: 0.942 ± 0.151
4.505AsnIle: 4.505 ± 0.347
3.93AsnLys: 3.93 ± 0.328
4.137AsnLeu: 4.137 ± 0.296
1.172AsnMet: 1.172 ± 0.156
3.93AsnAsn: 3.93 ± 0.357
3.057AsnPro: 3.057 ± 0.265
2.114AsnGln: 2.114 ± 0.197
2.712AsnArg: 2.712 ± 0.233
4.114AsnSer: 4.114 ± 0.294
2.873AsnThr: 2.873 ± 0.26
3.7AsnVal: 3.7 ± 0.351
0.735AsnTrp: 0.735 ± 0.123
2.022AsnTyr: 2.022 ± 0.273
0.0AsnXaa: 0.0 ± 0.0
Pro
1.931ProAla: 1.931 ± 0.187
0.345ProCys: 0.345 ± 0.084
2.436ProAsp: 2.436 ± 0.24
3.172ProGlu: 3.172 ± 0.319
2.022ProPhe: 2.022 ± 0.199
1.356ProGly: 1.356 ± 0.167
0.735ProHis: 0.735 ± 0.113
2.114ProIle: 2.114 ± 0.184
2.344ProLys: 2.344 ± 0.308
2.666ProLeu: 2.666 ± 0.272
0.758ProMet: 0.758 ± 0.109
2.298ProAsn: 2.298 ± 0.26
0.919ProPro: 0.919 ± 0.161
1.241ProGln: 1.241 ± 0.2
1.402ProArg: 1.402 ± 0.166
2.827ProSer: 2.827 ± 0.274
2.413ProThr: 2.413 ± 0.272
2.804ProVal: 2.804 ± 0.306
0.345ProTrp: 0.345 ± 0.113
1.839ProTyr: 1.839 ± 0.206
0.0ProXaa: 0.0 ± 0.0
Gln
2.735GlnAla: 2.735 ± 0.286
0.368GlnCys: 0.368 ± 0.089
1.885GlnAsp: 1.885 ± 0.179
2.321GlnGlu: 2.321 ± 0.197
2.091GlnPhe: 2.091 ± 0.252
1.885GlnGly: 1.885 ± 0.211
0.621GlnHis: 0.621 ± 0.12
2.919GlnIle: 2.919 ± 0.31
2.528GlnLys: 2.528 ± 0.274
3.539GlnLeu: 3.539 ± 0.3
1.057GlnMet: 1.057 ± 0.175
1.977GlnAsn: 1.977 ± 0.218
1.425GlnPro: 1.425 ± 0.22
1.287GlnGln: 1.287 ± 0.163
1.862GlnArg: 1.862 ± 0.213
2.367GlnSer: 2.367 ± 0.216
2.298GlnThr: 2.298 ± 0.269
2.413GlnVal: 2.413 ± 0.196
0.598GlnTrp: 0.598 ± 0.115
1.999GlnTyr: 1.999 ± 0.214
0.0GlnXaa: 0.0 ± 0.0
Arg
2.39ArgAla: 2.39 ± 0.236
0.483ArgCys: 0.483 ± 0.088
2.436ArgAsp: 2.436 ± 0.228
2.39ArgGlu: 2.39 ± 0.255
2.183ArgPhe: 2.183 ± 0.21
2.091ArgGly: 2.091 ± 0.193
0.942ArgHis: 0.942 ± 0.117
3.172ArgIle: 3.172 ± 0.342
2.988ArgLys: 2.988 ± 0.298
4.022ArgLeu: 4.022 ± 0.319
1.287ArgMet: 1.287 ± 0.174
2.551ArgAsn: 2.551 ± 0.239
1.034ArgPro: 1.034 ± 0.144
1.563ArgGln: 1.563 ± 0.179
1.724ArgArg: 1.724 ± 0.197
2.505ArgSer: 2.505 ± 0.236
2.436ArgThr: 2.436 ± 0.242
2.85ArgVal: 2.85 ± 0.26
0.46ArgTrp: 0.46 ± 0.094
2.022ArgTyr: 2.022 ± 0.208
0.0ArgXaa: 0.0 ± 0.0
Ser
3.884SerAla: 3.884 ± 0.372
0.712SerCys: 0.712 ± 0.127
3.608SerAsp: 3.608 ± 0.341
4.321SerGlu: 4.321 ± 0.306
3.149SerPhe: 3.149 ± 0.266
5.378SerGly: 5.378 ± 0.496
1.126SerHis: 1.126 ± 0.169
4.987SerIle: 4.987 ± 0.359
4.505SerLys: 4.505 ± 0.354
5.332SerLeu: 5.332 ± 0.385
1.356SerMet: 1.356 ± 0.168
4.459SerAsn: 4.459 ± 0.328
2.62SerPro: 2.62 ± 0.256
2.988SerGln: 2.988 ± 0.269
2.298SerArg: 2.298 ± 0.244
4.137SerSer: 4.137 ± 0.384
4.252SerThr: 4.252 ± 0.392
4.872SerVal: 4.872 ± 0.511
0.712SerTrp: 0.712 ± 0.127
2.367SerTyr: 2.367 ± 0.27
0.0SerXaa: 0.0 ± 0.0
Thr
3.608ThrAla: 3.608 ± 0.352
0.368ThrCys: 0.368 ± 0.101
4.367ThrAsp: 4.367 ± 0.357
3.746ThrGlu: 3.746 ± 0.281
3.355ThrPhe: 3.355 ± 0.285
3.838ThrGly: 3.838 ± 0.433
0.942ThrHis: 0.942 ± 0.139
3.861ThrIle: 3.861 ± 0.326
3.631ThrLys: 3.631 ± 0.304
5.516ThrLeu: 5.516 ± 0.331
1.218ThrMet: 1.218 ± 0.192
3.608ThrAsn: 3.608 ± 0.353
2.965ThrPro: 2.965 ± 0.24
2.528ThrGln: 2.528 ± 0.323
1.999ThrArg: 1.999 ± 0.202
3.562ThrSer: 3.562 ± 0.383
4.482ThrThr: 4.482 ± 0.342
4.39ThrVal: 4.39 ± 0.334
0.735ThrTrp: 0.735 ± 0.108
2.022ThrTyr: 2.022 ± 0.19
0.0ThrXaa: 0.0 ± 0.0
Val
4.688ValAla: 4.688 ± 0.333
0.758ValCys: 0.758 ± 0.139
5.309ValAsp: 5.309 ± 0.361
6.113ValGlu: 6.113 ± 0.446
2.712ValPhe: 2.712 ± 0.241
3.976ValGly: 3.976 ± 0.353
1.103ValHis: 1.103 ± 0.163
4.482ValIle: 4.482 ± 0.302
5.24ValLys: 5.24 ± 0.372
4.482ValLeu: 4.482 ± 0.316
1.563ValMet: 1.563 ± 0.174
3.953ValAsn: 3.953 ± 0.306
2.551ValPro: 2.551 ± 0.284
2.574ValGln: 2.574 ± 0.217
2.781ValArg: 2.781 ± 0.213
5.033ValSer: 5.033 ± 0.416
3.907ValThr: 3.907 ± 0.42
5.125ValVal: 5.125 ± 0.343
0.689ValTrp: 0.689 ± 0.139
2.252ValTyr: 2.252 ± 0.242
0.0ValXaa: 0.0 ± 0.0
Trp
0.781TrpAla: 0.781 ± 0.129
0.276TrpCys: 0.276 ± 0.113
0.621TrpAsp: 0.621 ± 0.124
0.506TrpGlu: 0.506 ± 0.127
0.666TrpPhe: 0.666 ± 0.144
0.781TrpGly: 0.781 ± 0.117
0.184TrpHis: 0.184 ± 0.076
0.85TrpIle: 0.85 ± 0.144
0.896TrpLys: 0.896 ± 0.132
0.919TrpLeu: 0.919 ± 0.164
0.322TrpMet: 0.322 ± 0.095
0.46TrpAsn: 0.46 ± 0.101
0.437TrpPro: 0.437 ± 0.106
0.46TrpGln: 0.46 ± 0.125
0.598TrpArg: 0.598 ± 0.13
0.666TrpSer: 0.666 ± 0.124
0.781TrpThr: 0.781 ± 0.136
0.758TrpVal: 0.758 ± 0.144
0.161TrpTrp: 0.161 ± 0.066
0.529TrpTyr: 0.529 ± 0.095
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.057TyrAla: 3.057 ± 0.281
0.644TyrCys: 0.644 ± 0.114
2.574TyrAsp: 2.574 ± 0.217
2.505TyrGlu: 2.505 ± 0.262
1.471TyrPhe: 1.471 ± 0.197
1.977TyrGly: 1.977 ± 0.212
0.942TyrHis: 0.942 ± 0.148
2.574TyrIle: 2.574 ± 0.235
2.666TyrLys: 2.666 ± 0.264
2.459TyrLeu: 2.459 ± 0.235
0.919TyrMet: 0.919 ± 0.163
2.781TyrAsn: 2.781 ± 0.262
1.333TyrPro: 1.333 ± 0.199
1.264TyrGln: 1.264 ± 0.181
1.954TyrArg: 1.954 ± 0.222
2.436TyrSer: 2.436 ± 0.281
2.689TyrThr: 2.689 ± 0.25
3.103TyrVal: 3.103 ± 0.26
0.552TyrTrp: 0.552 ± 0.124
1.31TyrTyr: 1.31 ± 0.157
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 177 proteins (43512 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski