Amino acid dipepetide frequency for Bovine adenovirus 4 (BAdV-4)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.22AlaAla: 4.22 ± 0.667
1.439AlaCys: 1.439 ± 0.363
2.59AlaAsp: 2.59 ± 0.51
3.357AlaGlu: 3.357 ± 0.416
3.357AlaPhe: 3.357 ± 0.655
1.822AlaGly: 1.822 ± 0.447
0.671AlaHis: 0.671 ± 0.222
3.357AlaIle: 3.357 ± 0.507
3.069AlaLys: 3.069 ± 0.685
5.467AlaLeu: 5.467 ± 0.806
1.151AlaMet: 1.151 ± 0.26
2.59AlaAsn: 2.59 ± 0.632
2.014AlaPro: 2.014 ± 0.355
2.206AlaGln: 2.206 ± 0.313
2.302AlaArg: 2.302 ± 0.479
4.412AlaSer: 4.412 ± 0.741
2.206AlaThr: 2.206 ± 0.576
3.261AlaVal: 3.261 ± 0.499
0.575AlaTrp: 0.575 ± 0.222
2.11AlaTyr: 2.11 ± 0.561
0.0AlaXaa: 0.0 ± 0.0
Cys
0.863CysAla: 0.863 ± 0.339
0.959CysCys: 0.959 ± 0.368
0.959CysAsp: 0.959 ± 0.32
1.631CysGlu: 1.631 ± 0.461
1.918CysPhe: 1.918 ± 0.451
1.439CysGly: 1.439 ± 0.392
1.535CysHis: 1.535 ± 0.384
0.863CysIle: 0.863 ± 0.346
2.686CysLys: 2.686 ± 0.73
2.973CysLeu: 2.973 ± 0.621
0.575CysMet: 0.575 ± 0.295
2.11CysAsn: 2.11 ± 0.437
0.863CysPro: 0.863 ± 0.315
0.48CysGln: 0.48 ± 0.219
0.575CysArg: 0.575 ± 0.259
2.11CysSer: 2.11 ± 0.416
0.671CysThr: 0.671 ± 0.24
1.343CysVal: 1.343 ± 0.356
0.096CysTrp: 0.096 ± 0.083
1.151CysTyr: 1.151 ± 0.379
0.0CysXaa: 0.0 ± 0.0
Asp
2.014AspAla: 2.014 ± 0.408
1.055AspCys: 1.055 ± 0.329
2.11AspAsp: 2.11 ± 0.45
2.973AspGlu: 2.973 ± 0.62
2.206AspPhe: 2.206 ± 0.416
1.631AspGly: 1.631 ± 0.3
1.151AspHis: 1.151 ± 0.336
3.357AspIle: 3.357 ± 0.622
3.069AspLys: 3.069 ± 0.683
5.275AspLeu: 5.275 ± 0.683
0.767AspMet: 0.767 ± 0.244
2.11AspAsn: 2.11 ± 0.511
2.782AspPro: 2.782 ± 0.539
1.055AspGln: 1.055 ± 0.289
2.59AspArg: 2.59 ± 0.779
3.741AspSer: 3.741 ± 0.656
2.494AspThr: 2.494 ± 0.651
2.59AspVal: 2.59 ± 0.497
0.575AspTrp: 0.575 ± 0.187
2.014AspTyr: 2.014 ± 0.39
0.0AspXaa: 0.0 ± 0.0
Glu
2.398GluAla: 2.398 ± 0.653
1.822GluCys: 1.822 ± 0.509
3.261GluAsp: 3.261 ± 0.576
5.755GluGlu: 5.755 ± 0.932
2.206GluPhe: 2.206 ± 0.449
2.686GluGly: 2.686 ± 0.791
0.48GluHis: 0.48 ± 0.222
3.837GluIle: 3.837 ± 0.559
3.645GluLys: 3.645 ± 0.914
4.124GluLeu: 4.124 ± 0.684
1.247GluMet: 1.247 ± 0.361
4.316GluAsn: 4.316 ± 0.609
2.398GluPro: 2.398 ± 0.489
1.822GluGln: 1.822 ± 0.444
3.069GluArg: 3.069 ± 0.517
3.453GluSer: 3.453 ± 0.69
4.124GluThr: 4.124 ± 0.584
2.398GluVal: 2.398 ± 0.428
1.631GluTrp: 1.631 ± 0.352
1.631GluTyr: 1.631 ± 0.392
0.0GluXaa: 0.0 ± 0.0
Phe
2.206PheAla: 2.206 ± 0.368
1.918PheCys: 1.918 ± 0.524
2.11PheAsp: 2.11 ± 0.426
2.206PheGlu: 2.206 ± 0.407
4.028PhePhe: 4.028 ± 0.601
1.439PheGly: 1.439 ± 0.408
1.439PheHis: 1.439 ± 0.382
3.165PheIle: 3.165 ± 0.587
3.453PheLys: 3.453 ± 0.586
7.002PheLeu: 7.002 ± 0.838
1.822PheMet: 1.822 ± 0.588
3.165PheAsn: 3.165 ± 0.475
3.069PhePro: 3.069 ± 0.559
2.782PheGln: 2.782 ± 0.465
2.206PheArg: 2.206 ± 0.45
3.645PheSer: 3.645 ± 0.48
1.918PheThr: 1.918 ± 0.399
3.741PheVal: 3.741 ± 0.552
1.535PheTrp: 1.535 ± 0.399
2.11PheTyr: 2.11 ± 0.395
0.0PheXaa: 0.0 ± 0.0
Gly
2.877GlyAla: 2.877 ± 0.584
0.863GlyCys: 0.863 ± 0.272
1.822GlyAsp: 1.822 ± 0.317
2.398GlyGlu: 2.398 ± 0.405
2.877GlyPhe: 2.877 ± 0.459
2.782GlyGly: 2.782 ± 0.523
1.343GlyHis: 1.343 ± 0.419
2.877GlyIle: 2.877 ± 0.473
4.028GlyLys: 4.028 ± 0.892
3.357GlyLeu: 3.357 ± 0.626
0.863GlyMet: 0.863 ± 0.254
2.973GlyAsn: 2.973 ± 0.565
1.439GlyPro: 1.439 ± 0.316
1.822GlyGln: 1.822 ± 0.358
2.11GlyArg: 2.11 ± 0.556
2.973GlySer: 2.973 ± 0.549
2.686GlyThr: 2.686 ± 0.552
2.59GlyVal: 2.59 ± 0.452
1.055GlyTrp: 1.055 ± 0.275
1.822GlyTyr: 1.822 ± 0.456
0.0GlyXaa: 0.0 ± 0.0
His
1.343HisAla: 1.343 ± 0.337
2.398HisCys: 2.398 ± 0.584
0.575HisAsp: 0.575 ± 0.231
0.671HisGlu: 0.671 ± 0.274
1.439HisPhe: 1.439 ± 0.366
0.767HisGly: 0.767 ± 0.315
0.288HisHis: 0.288 ± 0.149
1.726HisIle: 1.726 ± 0.532
0.671HisLys: 0.671 ± 0.209
3.069HisLeu: 3.069 ± 0.627
0.48HisMet: 0.48 ± 0.192
1.535HisAsn: 1.535 ± 0.419
1.631HisPro: 1.631 ± 0.412
0.575HisGln: 0.575 ± 0.233
1.631HisArg: 1.631 ± 0.346
1.918HisSer: 1.918 ± 0.408
1.055HisThr: 1.055 ± 0.268
0.863HisVal: 0.863 ± 0.234
0.288HisTrp: 0.288 ± 0.143
0.863HisTyr: 0.863 ± 0.339
0.0HisXaa: 0.0 ± 0.0
Ile
3.741IleAla: 3.741 ± 0.599
1.151IleCys: 1.151 ± 0.346
2.59IleAsp: 2.59 ± 0.418
3.069IleGlu: 3.069 ± 0.56
2.59IlePhe: 2.59 ± 0.388
3.261IleGly: 3.261 ± 0.579
0.959IleHis: 0.959 ± 0.297
2.302IleIle: 2.302 ± 0.341
3.453IleLys: 3.453 ± 0.666
6.043IleLeu: 6.043 ± 0.887
1.343IleMet: 1.343 ± 0.292
4.028IleAsn: 4.028 ± 0.756
3.453IlePro: 3.453 ± 0.665
3.069IleGln: 3.069 ± 0.612
2.973IleArg: 2.973 ± 0.877
4.412IleSer: 4.412 ± 0.57
3.549IleThr: 3.549 ± 0.537
4.22IleVal: 4.22 ± 0.636
0.959IleTrp: 0.959 ± 0.334
2.494IleTyr: 2.494 ± 0.49
0.0IleXaa: 0.0 ± 0.0
Lys
2.877LysAla: 2.877 ± 0.494
1.343LysCys: 1.343 ± 0.493
2.782LysAsp: 2.782 ± 0.449
2.494LysGlu: 2.494 ± 0.628
3.837LysPhe: 3.837 ± 0.577
2.494LysGly: 2.494 ± 0.445
1.918LysHis: 1.918 ± 0.352
4.508LysIle: 4.508 ± 0.707
5.851LysLys: 5.851 ± 1.042
7.865LysLeu: 7.865 ± 1.147
1.343LysMet: 1.343 ± 0.363
4.124LysAsn: 4.124 ± 0.541
2.686LysPro: 2.686 ± 0.484
2.59LysGln: 2.59 ± 0.561
4.508LysArg: 4.508 ± 0.707
4.028LysSer: 4.028 ± 0.685
3.261LysThr: 3.261 ± 0.836
2.302LysVal: 2.302 ± 0.607
0.959LysTrp: 0.959 ± 0.276
2.686LysTyr: 2.686 ± 0.441
0.0LysXaa: 0.0 ± 0.0
Leu
5.755LeuAla: 5.755 ± 0.913
2.302LeuCys: 2.302 ± 0.532
4.316LeuAsp: 4.316 ± 0.639
5.947LeuGlu: 5.947 ± 0.774
3.932LeuPhe: 3.932 ± 0.591
3.549LeuGly: 3.549 ± 0.575
2.686LeuHis: 2.686 ± 0.561
5.563LeuIle: 5.563 ± 0.642
8.153LeuLys: 8.153 ± 0.849
10.646LeuLeu: 10.646 ± 1.243
2.014LeuMet: 2.014 ± 0.575
7.002LeuAsn: 7.002 ± 0.656
7.002LeuPro: 7.002 ± 0.647
5.275LeuGln: 5.275 ± 0.597
6.043LeuArg: 6.043 ± 0.863
8.728LeuSer: 8.728 ± 1.414
7.769LeuThr: 7.769 ± 1.252
3.549LeuVal: 3.549 ± 0.526
2.302LeuTrp: 2.302 ± 0.634
4.22LeuTyr: 4.22 ± 0.708
0.0LeuXaa: 0.0 ± 0.0
Met
1.439MetAla: 1.439 ± 0.343
0.192MetCys: 0.192 ± 0.128
1.151MetAsp: 1.151 ± 0.356
1.726MetGlu: 1.726 ± 0.424
0.863MetPhe: 0.863 ± 0.298
0.959MetGly: 0.959 ± 0.455
0.192MetHis: 0.192 ± 0.12
0.959MetIle: 0.959 ± 0.38
1.247MetLys: 1.247 ± 0.318
2.686MetLeu: 2.686 ± 0.491
0.48MetMet: 0.48 ± 0.22
1.535MetAsn: 1.535 ± 0.477
0.671MetPro: 0.671 ± 0.239
0.959MetGln: 0.959 ± 0.261
0.671MetArg: 0.671 ± 0.229
1.151MetSer: 1.151 ± 0.356
0.863MetThr: 0.863 ± 0.299
0.959MetVal: 0.959 ± 0.256
0.575MetTrp: 0.575 ± 0.273
1.247MetTyr: 1.247 ± 0.305
0.0MetXaa: 0.0 ± 0.0
Asn
3.357AsnAla: 3.357 ± 0.484
1.631AsnCys: 1.631 ± 0.412
3.165AsnAsp: 3.165 ± 0.639
2.973AsnGlu: 2.973 ± 0.439
4.124AsnPhe: 4.124 ± 0.838
2.686AsnGly: 2.686 ± 0.531
1.343AsnHis: 1.343 ± 0.394
4.604AsnIle: 4.604 ± 0.609
3.069AsnLys: 3.069 ± 0.519
6.906AsnLeu: 6.906 ± 0.919
1.247AsnMet: 1.247 ± 0.467
3.932AsnAsn: 3.932 ± 0.626
4.028AsnPro: 4.028 ± 0.567
2.206AsnGln: 2.206 ± 0.589
2.494AsnArg: 2.494 ± 0.479
4.412AsnSer: 4.412 ± 0.866
3.261AsnThr: 3.261 ± 0.56
3.741AsnVal: 3.741 ± 0.898
0.671AsnTrp: 0.671 ± 0.288
2.877AsnTyr: 2.877 ± 0.565
0.0AsnXaa: 0.0 ± 0.0
Pro
2.302ProAla: 2.302 ± 0.492
0.959ProCys: 0.959 ± 0.295
2.686ProAsp: 2.686 ± 0.481
3.741ProGlu: 3.741 ± 0.624
4.7ProPhe: 4.7 ± 0.688
1.918ProGly: 1.918 ± 0.383
1.343ProHis: 1.343 ± 0.364
2.973ProIle: 2.973 ± 0.353
2.302ProLys: 2.302 ± 0.42
5.083ProLeu: 5.083 ± 1.079
1.151ProMet: 1.151 ± 0.38
2.973ProAsn: 2.973 ± 0.78
4.028ProPro: 4.028 ± 0.559
1.343ProGln: 1.343 ± 0.407
2.206ProArg: 2.206 ± 0.403
4.412ProSer: 4.412 ± 0.683
2.782ProThr: 2.782 ± 0.29
3.069ProVal: 3.069 ± 0.49
0.575ProTrp: 0.575 ± 0.204
2.494ProTyr: 2.494 ± 0.579
0.0ProXaa: 0.0 ± 0.0
Gln
1.822GlnAla: 1.822 ± 0.444
1.247GlnCys: 1.247 ± 0.52
1.631GlnAsp: 1.631 ± 0.471
1.822GlnGlu: 1.822 ± 0.519
0.959GlnPhe: 0.959 ± 0.305
1.631GlnGly: 1.631 ± 0.398
0.959GlnHis: 0.959 ± 0.262
3.165GlnIle: 3.165 ± 0.468
3.069GlnLys: 3.069 ± 0.507
4.604GlnLeu: 4.604 ± 0.475
1.055GlnMet: 1.055 ± 0.273
2.782GlnAsn: 2.782 ± 0.617
1.918GlnPro: 1.918 ± 0.29
1.726GlnGln: 1.726 ± 0.426
2.11GlnArg: 2.11 ± 0.493
2.973GlnSer: 2.973 ± 0.642
2.782GlnThr: 2.782 ± 0.581
2.398GlnVal: 2.398 ± 0.437
0.671GlnTrp: 0.671 ± 0.254
1.343GlnTyr: 1.343 ± 0.46
0.0GlnXaa: 0.0 ± 0.0
Arg
3.069ArgAla: 3.069 ± 0.727
0.767ArgCys: 0.767 ± 0.273
2.398ArgAsp: 2.398 ± 0.571
2.973ArgGlu: 2.973 ± 0.71
2.398ArgPhe: 2.398 ± 0.475
2.494ArgGly: 2.494 ± 0.365
0.959ArgHis: 0.959 ± 0.25
2.494ArgIle: 2.494 ± 0.374
2.59ArgLys: 2.59 ± 0.504
5.947ArgLeu: 5.947 ± 0.81
0.767ArgMet: 0.767 ± 0.313
3.261ArgAsn: 3.261 ± 0.537
2.014ArgPro: 2.014 ± 0.425
1.726ArgGln: 1.726 ± 0.415
4.028ArgArg: 4.028 ± 1.023
2.877ArgSer: 2.877 ± 0.532
2.686ArgThr: 2.686 ± 0.506
2.973ArgVal: 2.973 ± 0.543
0.767ArgTrp: 0.767 ± 0.201
1.247ArgTyr: 1.247 ± 0.306
0.0ArgXaa: 0.0 ± 0.0
Ser
3.165SerAla: 3.165 ± 0.414
1.822SerCys: 1.822 ± 0.585
3.357SerAsp: 3.357 ± 0.587
5.083SerGlu: 5.083 ± 0.622
4.316SerPhe: 4.316 ± 0.729
5.083SerGly: 5.083 ± 0.684
1.918SerHis: 1.918 ± 0.481
4.412SerIle: 4.412 ± 0.584
4.604SerLys: 4.604 ± 0.895
7.673SerLeu: 7.673 ± 1.102
1.439SerMet: 1.439 ± 0.417
4.796SerAsn: 4.796 ± 0.786
3.549SerPro: 3.549 ± 0.806
3.549SerGln: 3.549 ± 0.737
2.782SerArg: 2.782 ± 0.55
5.755SerSer: 5.755 ± 0.757
2.973SerThr: 2.973 ± 0.478
3.837SerVal: 3.837 ± 0.539
0.863SerTrp: 0.863 ± 0.277
3.165SerTyr: 3.165 ± 0.436
0.0SerXaa: 0.0 ± 0.0
Thr
3.645ThrAla: 3.645 ± 0.612
1.151ThrCys: 1.151 ± 0.284
3.261ThrAsp: 3.261 ± 0.62
2.494ThrGlu: 2.494 ± 0.521
2.686ThrPhe: 2.686 ± 0.422
2.782ThrGly: 2.782 ± 0.589
1.726ThrHis: 1.726 ± 0.431
2.782ThrIle: 2.782 ± 0.613
2.11ThrLys: 2.11 ± 0.522
5.659ThrLeu: 5.659 ± 0.751
0.671ThrMet: 0.671 ± 0.217
2.877ThrAsn: 2.877 ± 0.596
3.165ThrPro: 3.165 ± 0.517
2.206ThrGln: 2.206 ± 0.304
2.014ThrArg: 2.014 ± 0.466
3.932ThrSer: 3.932 ± 0.584
3.357ThrThr: 3.357 ± 0.567
4.604ThrVal: 4.604 ± 0.712
1.151ThrTrp: 1.151 ± 0.283
2.782ThrTyr: 2.782 ± 0.493
0.0ThrXaa: 0.0 ± 0.0
Val
3.357ValAla: 3.357 ± 0.469
0.575ValCys: 0.575 ± 0.247
2.206ValAsp: 2.206 ± 0.465
2.302ValGlu: 2.302 ± 0.509
2.59ValPhe: 2.59 ± 0.478
2.11ValGly: 2.11 ± 0.45
1.535ValHis: 1.535 ± 0.423
4.412ValIle: 4.412 ± 0.585
3.837ValLys: 3.837 ± 0.777
6.426ValLeu: 6.426 ± 0.731
0.288ValMet: 0.288 ± 0.184
2.973ValAsn: 2.973 ± 0.724
2.973ValPro: 2.973 ± 0.541
2.302ValGln: 2.302 ± 0.376
1.918ValArg: 1.918 ± 0.468
4.028ValSer: 4.028 ± 0.538
3.645ValThr: 3.645 ± 0.724
2.494ValVal: 2.494 ± 0.41
0.671ValTrp: 0.671 ± 0.265
2.014ValTyr: 2.014 ± 0.567
0.0ValXaa: 0.0 ± 0.0
Trp
0.575TrpAla: 0.575 ± 0.227
1.055TrpCys: 1.055 ± 0.363
0.575TrpAsp: 0.575 ± 0.176
0.959TrpGlu: 0.959 ± 0.465
0.575TrpPhe: 0.575 ± 0.185
1.055TrpGly: 1.055 ± 0.266
0.096TrpHis: 0.096 ± 0.101
0.384TrpIle: 0.384 ± 0.194
1.918TrpLys: 1.918 ± 0.594
1.247TrpLeu: 1.247 ± 0.387
0.48TrpMet: 0.48 ± 0.204
0.959TrpAsn: 0.959 ± 0.308
1.343TrpPro: 1.343 ± 0.372
0.863TrpGln: 0.863 ± 0.248
0.863TrpArg: 0.863 ± 0.317
1.151TrpSer: 1.151 ± 0.355
1.247TrpThr: 1.247 ± 0.338
0.384TrpVal: 0.384 ± 0.18
0.192TrpTrp: 0.192 ± 0.124
1.055TrpTyr: 1.055 ± 0.435
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.151TyrAla: 1.151 ± 0.269
1.151TyrCys: 1.151 ± 0.331
2.014TyrAsp: 2.014 ± 0.715
1.726TyrGlu: 1.726 ± 0.421
3.357TyrPhe: 3.357 ± 0.56
2.973TyrGly: 2.973 ± 0.753
1.247TyrHis: 1.247 ± 0.378
1.918TyrIle: 1.918 ± 0.418
1.631TyrLys: 1.631 ± 0.426
4.7TyrLeu: 4.7 ± 0.763
1.247TyrMet: 1.247 ± 0.316
2.686TyrAsn: 2.686 ± 0.487
2.014TyrPro: 2.014 ± 0.444
2.11TyrGln: 2.11 ± 0.47
1.439TyrArg: 1.439 ± 0.336
4.028TyrSer: 4.028 ± 0.825
1.726TyrThr: 1.726 ± 0.384
1.343TyrVal: 1.343 ± 0.371
0.863TyrTrp: 0.863 ± 0.321
1.439TyrTyr: 1.439 ± 0.383
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 36 proteins (10427 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski