Amino acid dipepetide frequency for Hubei tombus-like virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.602AlaAla: 5.602 ± 4.933
1.401AlaCys: 1.401 ± 1.898
7.003AlaAsp: 7.003 ± 1.511
4.202AlaGlu: 4.202 ± 3.035
4.202AlaPhe: 4.202 ± 0.374
1.401AlaGly: 1.401 ± 0.762
0.0AlaHis: 0.0 ± 0.0
5.602AlaIle: 5.602 ± 2.273
4.202AlaLys: 4.202 ± 0.374
8.403AlaLeu: 8.403 ± 6.069
5.602AlaMet: 5.602 ± 3.048
5.602AlaAsn: 5.602 ± 4.933
4.202AlaPro: 4.202 ± 2.286
1.401AlaGln: 1.401 ± 1.898
8.403AlaArg: 8.403 ± 6.069
2.801AlaSer: 2.801 ± 1.524
4.202AlaThr: 4.202 ± 3.035
9.804AlaVal: 9.804 ± 0.013
2.801AlaTrp: 2.801 ± 1.524
1.401AlaTyr: 1.401 ± 1.898
0.0AlaXaa: 0.0 ± 0.0
Cys
4.202CysAla: 4.202 ± 0.374
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.401CysPhe: 1.401 ± 0.762
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.801CysIle: 2.801 ± 1.136
2.801CysLys: 2.801 ± 1.136
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.401CysGln: 1.401 ± 0.762
0.0CysArg: 0.0 ± 0.0
1.401CysSer: 1.401 ± 0.762
0.0CysThr: 0.0 ± 0.0
4.202CysVal: 4.202 ± 2.286
0.0CysTrp: 0.0 ± 0.0
1.401CysTyr: 1.401 ± 0.762
0.0CysXaa: 0.0 ± 0.0
Asp
8.403AspAla: 8.403 ± 0.749
1.401AspCys: 1.401 ± 0.762
1.401AspAsp: 1.401 ± 0.762
8.403AspGlu: 8.403 ± 1.911
4.202AspPhe: 4.202 ± 0.374
2.801AspGly: 2.801 ± 1.136
1.401AspHis: 1.401 ± 0.762
1.401AspIle: 1.401 ± 0.762
0.0AspLys: 0.0 ± 0.0
8.403AspLeu: 8.403 ± 3.409
1.401AspMet: 1.401 ± 0.762
1.401AspAsn: 1.401 ± 1.898
2.801AspPro: 2.801 ± 1.136
1.401AspGln: 1.401 ± 0.762
2.801AspArg: 2.801 ± 1.524
4.202AspSer: 4.202 ± 0.374
2.801AspThr: 2.801 ± 1.524
0.0AspVal: 0.0 ± 0.0
0.0AspTrp: 0.0 ± 0.0
2.801AspTyr: 2.801 ± 1.524
0.0AspXaa: 0.0 ± 0.0
Glu
7.003GluAla: 7.003 ± 4.171
2.801GluCys: 2.801 ± 3.797
1.401GluAsp: 1.401 ± 0.762
2.801GluGlu: 2.801 ± 1.524
7.003GluPhe: 7.003 ± 1.511
2.801GluGly: 2.801 ± 1.524
1.401GluHis: 1.401 ± 0.762
4.202GluIle: 4.202 ± 0.374
2.801GluLys: 2.801 ± 1.524
7.003GluLeu: 7.003 ± 1.149
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
4.202GluPro: 4.202 ± 2.286
4.202GluGln: 4.202 ± 0.374
8.403GluArg: 8.403 ± 6.069
4.202GluSer: 4.202 ± 3.035
2.801GluThr: 2.801 ± 1.524
1.401GluVal: 1.401 ± 0.762
1.401GluTrp: 1.401 ± 0.762
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.401PheAla: 1.401 ± 1.898
1.401PheCys: 1.401 ± 0.762
2.801PheAsp: 2.801 ± 1.136
4.202PheGlu: 4.202 ± 2.286
2.801PhePhe: 2.801 ± 1.136
2.801PheGly: 2.801 ± 1.136
2.801PheHis: 2.801 ± 1.524
0.0PheIle: 0.0 ± 0.0
1.401PheLys: 1.401 ± 0.762
1.401PheLeu: 1.401 ± 1.898
1.401PheMet: 1.401 ± 0.762
2.801PheAsn: 2.801 ± 1.524
1.401PhePro: 1.401 ± 0.762
2.801PheGln: 2.801 ± 1.524
7.003PheArg: 7.003 ± 1.149
4.202PheSer: 4.202 ± 3.035
1.401PheThr: 1.401 ± 0.762
8.403PheVal: 8.403 ± 0.749
0.0PheTrp: 0.0 ± 0.0
4.202PheTyr: 4.202 ± 2.286
0.0PheXaa: 0.0 ± 0.0
Gly
2.801GlyAla: 2.801 ± 1.136
0.0GlyCys: 0.0 ± 0.0
5.602GlyAsp: 5.602 ± 3.048
1.401GlyGlu: 1.401 ± 0.762
2.801GlyPhe: 2.801 ± 1.524
2.801GlyGly: 2.801 ± 1.524
0.0GlyHis: 0.0 ± 0.0
1.401GlyIle: 1.401 ± 0.762
2.801GlyLys: 2.801 ± 1.524
4.202GlyLeu: 4.202 ± 2.286
2.801GlyMet: 2.801 ± 1.524
1.401GlyAsn: 1.401 ± 0.762
2.801GlyPro: 2.801 ± 1.136
0.0GlyGln: 0.0 ± 0.0
5.602GlyArg: 5.602 ± 3.048
2.801GlySer: 2.801 ± 3.797
2.801GlyThr: 2.801 ± 1.524
12.605GlyVal: 12.605 ± 1.537
1.401GlyTrp: 1.401 ± 1.898
1.401GlyTyr: 1.401 ± 0.762
0.0GlyXaa: 0.0 ± 0.0
His
1.401HisAla: 1.401 ± 0.762
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.401HisGlu: 1.401 ± 0.762
2.801HisPhe: 2.801 ± 1.524
1.401HisGly: 1.401 ± 0.762
1.401HisHis: 1.401 ± 0.762
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.401HisAsn: 1.401 ± 0.762
4.202HisPro: 4.202 ± 2.286
0.0HisGln: 0.0 ± 0.0
1.401HisArg: 1.401 ± 1.898
2.801HisSer: 2.801 ± 1.524
0.0HisThr: 0.0 ± 0.0
1.401HisVal: 1.401 ± 0.762
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.801IleAla: 2.801 ± 3.797
0.0IleCys: 0.0 ± 0.0
1.401IleAsp: 1.401 ± 0.762
7.003IleGlu: 7.003 ± 1.511
1.401IlePhe: 1.401 ± 0.762
0.0IleGly: 0.0 ± 0.0
1.401IleHis: 1.401 ± 0.762
1.401IleIle: 1.401 ± 1.898
2.801IleLys: 2.801 ± 1.524
1.401IleLeu: 1.401 ± 1.898
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
2.801IleArg: 2.801 ± 3.797
4.202IleSer: 4.202 ± 0.374
0.0IleThr: 0.0 ± 0.0
1.401IleVal: 1.401 ± 1.898
0.0IleTrp: 0.0 ± 0.0
5.602IleTyr: 5.602 ± 3.048
0.0IleXaa: 0.0 ± 0.0
Lys
7.003LysAla: 7.003 ± 1.511
2.801LysCys: 2.801 ± 1.524
5.602LysAsp: 5.602 ± 2.273
4.202LysGlu: 4.202 ± 0.374
2.801LysPhe: 2.801 ± 1.136
1.401LysGly: 1.401 ± 0.762
1.401LysHis: 1.401 ± 0.762
1.401LysIle: 1.401 ± 0.762
1.401LysLys: 1.401 ± 0.762
2.801LysLeu: 2.801 ± 1.524
0.0LysMet: 0.0 ± 0.0
1.401LysAsn: 1.401 ± 0.762
2.801LysPro: 2.801 ± 1.524
1.401LysGln: 1.401 ± 0.762
4.202LysArg: 4.202 ± 2.286
2.801LysSer: 2.801 ± 1.524
5.602LysThr: 5.602 ± 3.048
1.401LysVal: 1.401 ± 0.762
2.801LysTrp: 2.801 ± 1.524
4.202LysTyr: 4.202 ± 2.286
0.0LysXaa: 0.0 ± 0.0
Leu
12.605LeuAla: 12.605 ± 1.123
0.0LeuCys: 0.0 ± 0.0
9.804LeuAsp: 9.804 ± 0.013
5.602LeuGlu: 5.602 ± 2.273
2.801LeuPhe: 2.801 ± 1.524
2.801LeuGly: 2.801 ± 1.524
0.0LeuHis: 0.0 ± 0.0
1.401LeuIle: 1.401 ± 1.898
2.801LeuLys: 2.801 ± 1.524
5.602LeuLeu: 5.602 ± 3.048
2.801LeuMet: 2.801 ± 1.954
0.0LeuAsn: 0.0 ± 0.0
8.403LeuPro: 8.403 ± 0.749
4.202LeuGln: 4.202 ± 2.286
8.403LeuArg: 8.403 ± 6.069
7.003LeuSer: 7.003 ± 1.511
1.401LeuThr: 1.401 ± 1.898
2.801LeuVal: 2.801 ± 1.136
1.401LeuTrp: 1.401 ± 0.762
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
2.801MetCys: 2.801 ± 1.524
0.0MetAsp: 0.0 ± 0.0
4.202MetGlu: 4.202 ± 0.374
0.0MetPhe: 0.0 ± 0.0
2.801MetGly: 2.801 ± 1.136
0.0MetHis: 0.0 ± 0.0
1.401MetIle: 1.401 ± 0.762
1.401MetLys: 1.401 ± 0.762
1.401MetLeu: 1.401 ± 0.762
0.0MetMet: 0.0 ± 0.0
2.801MetAsn: 2.801 ± 1.524
0.0MetPro: 0.0 ± 0.0
1.401MetGln: 1.401 ± 1.898
1.401MetArg: 1.401 ± 1.898
1.401MetSer: 1.401 ± 0.762
1.401MetThr: 1.401 ± 0.762
5.602MetVal: 5.602 ± 0.387
0.0MetTrp: 0.0 ± 0.0
1.401MetTyr: 1.401 ± 0.762
0.0MetXaa: 0.0 ± 0.0
Asn
2.801AsnAla: 2.801 ± 1.136
1.401AsnCys: 1.401 ± 0.762
4.202AsnAsp: 4.202 ± 0.374
1.401AsnGlu: 1.401 ± 1.898
0.0AsnPhe: 0.0 ± 0.0
1.401AsnGly: 1.401 ± 0.762
1.401AsnHis: 1.401 ± 1.898
0.0AsnIle: 0.0 ± 0.0
1.401AsnLys: 1.401 ± 0.762
1.401AsnLeu: 1.401 ± 1.898
2.801AsnMet: 2.801 ± 1.136
2.801AsnAsn: 2.801 ± 1.524
1.401AsnPro: 1.401 ± 0.762
0.0AsnGln: 0.0 ± 0.0
1.401AsnArg: 1.401 ± 1.898
0.0AsnSer: 0.0 ± 0.0
1.401AsnThr: 1.401 ± 0.762
2.801AsnVal: 2.801 ± 1.136
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.202ProAla: 4.202 ± 3.035
1.401ProCys: 1.401 ± 0.762
4.202ProAsp: 4.202 ± 2.286
1.401ProGlu: 1.401 ± 0.762
2.801ProPhe: 2.801 ± 3.797
0.0ProGly: 0.0 ± 0.0
1.401ProHis: 1.401 ± 0.762
2.801ProIle: 2.801 ± 1.524
5.602ProLys: 5.602 ± 3.048
7.003ProLeu: 7.003 ± 1.149
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
4.202ProPro: 4.202 ± 0.374
1.401ProGln: 1.401 ± 0.762
5.602ProArg: 5.602 ± 3.048
0.0ProSer: 0.0 ± 0.0
1.401ProThr: 1.401 ± 0.762
2.801ProVal: 2.801 ± 1.524
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.401GlnCys: 1.401 ± 0.762
2.801GlnAsp: 2.801 ± 1.136
1.401GlnGlu: 1.401 ± 1.898
1.401GlnPhe: 1.401 ± 0.762
1.401GlnGly: 1.401 ± 0.762
1.401GlnHis: 1.401 ± 0.762
0.0GlnIle: 0.0 ± 0.0
1.401GlnLys: 1.401 ± 1.898
2.801GlnLeu: 2.801 ± 1.524
1.401GlnMet: 1.401 ± 1.049
0.0GlnAsn: 0.0 ± 0.0
1.401GlnPro: 1.401 ± 0.762
1.401GlnGln: 1.401 ± 0.762
2.801GlnArg: 2.801 ± 1.136
2.801GlnSer: 2.801 ± 1.524
1.401GlnThr: 1.401 ± 0.762
4.202GlnVal: 4.202 ± 2.286
1.401GlnTrp: 1.401 ± 0.762
1.401GlnTyr: 1.401 ± 0.762
0.0GlnXaa: 0.0 ± 0.0
Arg
8.403ArgAla: 8.403 ± 1.911
0.0ArgCys: 0.0 ± 0.0
7.003ArgAsp: 7.003 ± 1.511
4.202ArgGlu: 4.202 ± 3.035
4.202ArgPhe: 4.202 ± 0.374
8.403ArgGly: 8.403 ± 0.749
1.401ArgHis: 1.401 ± 0.762
2.801ArgIle: 2.801 ± 1.136
11.204ArgLys: 11.204 ± 3.435
4.202ArgLeu: 4.202 ± 0.374
4.202ArgMet: 4.202 ± 0.374
4.202ArgAsn: 4.202 ± 3.035
0.0ArgPro: 0.0 ± 0.0
1.401ArgGln: 1.401 ± 1.898
8.403ArgArg: 8.403 ± 6.069
2.801ArgSer: 2.801 ± 1.136
5.602ArgThr: 5.602 ± 0.387
8.403ArgVal: 8.403 ± 3.409
2.801ArgTrp: 2.801 ± 1.136
2.801ArgTyr: 2.801 ± 1.524
0.0ArgXaa: 0.0 ± 0.0
Ser
7.003SerAla: 7.003 ± 9.491
0.0SerCys: 0.0 ± 0.0
1.401SerAsp: 1.401 ± 0.762
0.0SerGlu: 0.0 ± 0.0
5.602SerPhe: 5.602 ± 0.387
7.003SerGly: 7.003 ± 3.81
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
4.202SerLys: 4.202 ± 0.374
8.403SerLeu: 8.403 ± 1.911
4.202SerMet: 4.202 ± 0.374
1.401SerAsn: 1.401 ± 1.898
2.801SerPro: 2.801 ± 1.524
2.801SerGln: 2.801 ± 1.524
4.202SerArg: 4.202 ± 0.374
7.003SerSer: 7.003 ± 1.149
1.401SerThr: 1.401 ± 0.762
4.202SerVal: 4.202 ± 0.374
1.401SerTrp: 1.401 ± 0.762
1.401SerTyr: 1.401 ± 1.898
0.0SerXaa: 0.0 ± 0.0
Thr
5.602ThrAla: 5.602 ± 2.273
0.0ThrCys: 0.0 ± 0.0
1.401ThrAsp: 1.401 ± 0.762
2.801ThrGlu: 2.801 ± 1.136
1.401ThrPhe: 1.401 ± 0.762
2.801ThrGly: 2.801 ± 1.524
2.801ThrHis: 2.801 ± 1.524
2.801ThrIle: 2.801 ± 1.136
4.202ThrLys: 4.202 ± 0.374
4.202ThrLeu: 4.202 ± 0.374
0.0ThrMet: 0.0 ± 0.0
0.0ThrAsn: 0.0 ± 0.0
0.0ThrPro: 0.0 ± 0.0
1.401ThrGln: 1.401 ± 0.762
5.602ThrArg: 5.602 ± 0.387
5.602ThrSer: 5.602 ± 0.387
2.801ThrThr: 2.801 ± 3.797
2.801ThrVal: 2.801 ± 1.136
0.0ThrTrp: 0.0 ± 0.0
1.401ThrTyr: 1.401 ± 0.762
0.0ThrXaa: 0.0 ± 0.0
Val
2.801ValAla: 2.801 ± 1.524
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
9.804ValGlu: 9.804 ± 0.013
5.602ValPhe: 5.602 ± 3.048
9.804ValGly: 9.804 ± 0.013
1.401ValHis: 1.401 ± 0.762
2.801ValIle: 2.801 ± 1.136
5.602ValLys: 5.602 ± 3.048
7.003ValLeu: 7.003 ± 1.511
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
4.202ValPro: 4.202 ± 0.374
2.801ValGln: 2.801 ± 1.136
11.204ValArg: 11.204 ± 6.095
4.202ValSer: 4.202 ± 0.374
8.403ValThr: 8.403 ± 8.73
4.202ValVal: 4.202 ± 0.374
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
2.801TrpAla: 2.801 ± 1.524
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.401TrpGlu: 1.401 ± 0.762
1.401TrpPhe: 1.401 ± 0.762
2.801TrpGly: 2.801 ± 1.524
0.0TrpHis: 0.0 ± 0.0
1.401TrpIle: 1.401 ± 1.898
0.0TrpLys: 0.0 ± 0.0
1.401TrpLeu: 1.401 ± 0.762
1.401TrpMet: 1.401 ± 1.898
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.401TrpGln: 1.401 ± 0.762
1.401TrpArg: 1.401 ± 0.762
1.401TrpSer: 1.401 ± 0.762
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.401TyrAla: 1.401 ± 0.762
2.801TyrCys: 2.801 ± 1.524
1.401TyrAsp: 1.401 ± 0.762
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
2.801TyrGly: 2.801 ± 1.524
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.401TyrLys: 1.401 ± 0.762
4.202TyrLeu: 4.202 ± 0.374
0.0TyrMet: 0.0 ± 0.0
2.801TyrAsn: 2.801 ± 1.136
1.401TyrPro: 1.401 ± 0.762
1.401TyrGln: 1.401 ± 0.762
1.401TyrArg: 1.401 ± 0.762
2.801TyrSer: 2.801 ± 1.524
2.801TyrThr: 2.801 ± 1.524
1.401TyrVal: 1.401 ± 0.762
1.401TyrTrp: 1.401 ± 0.762
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (715 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski