Amino acid dipepetide frequency for Mucor ambiguus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.291AlaAla: 7.291 ± 0.06	0.992AlaCys: 0.992 ± 0.015	3.575AlaAsp: 3.575 ± 0.026	3.955AlaGlu: 3.955 ± 0.029	2.763AlaPhe: 2.763 ± 0.025	3.543AlaGly: 3.543 ± 0.036	1.533AlaHis: 1.533 ± 0.015	4.484AlaIle: 4.484 ± 0.036	4.238AlaLys: 4.238 ± 0.033	6.534AlaLeu: 6.534 ± 0.04	1.901AlaMet: 1.901 ± 0.021	3.415AlaAsn: 3.415 ± 0.026	3.295AlaPro: 3.295 ± 0.029	2.901AlaGln: 2.901 ± 0.033	3.031AlaArg: 3.031 ± 0.03	6.595AlaSer: 6.595 ± 0.044	5.223AlaThr: 5.223 ± 0.044	4.593AlaVal: 4.593 ± 0.035	0.717AlaTrp: 0.717 ± 0.012	2.161AlaTyr: 2.161 ± 0.021	0.001AlaXaa: 0.001 ± 0.0
Cys	0.797CysAla: 0.797 ± 0.013	0.417CysCys: 0.417 ± 0.017	0.693CysAsp: 0.693 ± 0.012	0.613CysGlu: 0.613 ± 0.012	0.617CysPhe: 0.617 ± 0.011	0.833CysGly: 0.833 ± 0.015	0.392CysHis: 0.392 ± 0.009	0.925CysIle: 0.925 ± 0.015	0.716CysLys: 0.716 ± 0.013	1.364CysLeu: 1.364 ± 0.018	0.319CysMet: 0.319 ± 0.009	0.603CysAsn: 0.603 ± 0.011	0.63CysPro: 0.63 ± 0.013	0.594CysGln: 0.594 ± 0.01	0.684CysArg: 0.684 ± 0.012	1.05CysSer: 1.05 ± 0.013	0.72CysThr: 0.72 ± 0.012	0.83CysVal: 0.83 ± 0.013	0.18CysTrp: 0.18 ± 0.006	0.483CysTyr: 0.483 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	4.087AspAla: 4.087 ± 0.027	0.656AspCys: 0.656 ± 0.012	4.808AspAsp: 4.808 ± 0.048	4.61AspGlu: 4.61 ± 0.045	2.29AspPhe: 2.29 ± 0.023	2.893AspGly: 2.893 ± 0.026	1.398AspHis: 1.398 ± 0.019	3.817AspIle: 3.817 ± 0.029	3.175AspLys: 3.175 ± 0.028	5.096AspLeu: 5.096 ± 0.036	1.617AspMet: 1.617 ± 0.017	2.633AspAsn: 2.633 ± 0.025	2.552AspPro: 2.552 ± 0.027	2.546AspGln: 2.546 ± 0.023	2.428AspArg: 2.428 ± 0.025	3.962AspSer: 3.962 ± 0.027	3.472AspThr: 3.472 ± 0.028	3.486AspVal: 3.486 ± 0.027	0.701AspTrp: 0.701 ± 0.012	2.066AspTyr: 2.066 ± 0.022	0.002AspXaa: 0.002 ± 0.001
Glu	4.49GluAla: 4.49 ± 0.036	0.69GluCys: 0.69 ± 0.012	4.343GluAsp: 4.343 ± 0.042	5.879GluGlu: 5.879 ± 0.069	2.168GluPhe: 2.168 ± 0.021	2.666GluGly: 2.666 ± 0.026	1.486GluHis: 1.486 ± 0.018	3.334GluIle: 3.334 ± 0.025	4.555GluLys: 4.555 ± 0.039	5.317GluLeu: 5.317 ± 0.042	1.48GluMet: 1.48 ± 0.016	2.935GluAsn: 2.935 ± 0.027	2.184GluPro: 2.184 ± 0.023	3.257GluGln: 3.257 ± 0.032	3.107GluArg: 3.107 ± 0.032	4.172GluSer: 4.172 ± 0.032	3.269GluThr: 3.269 ± 0.027	2.793GluVal: 2.793 ± 0.027	0.682GluTrp: 0.682 ± 0.013	2.007GluTyr: 2.007 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	2.693PheAla: 2.693 ± 0.022	0.635PheCys: 0.635 ± 0.013	2.536PheAsp: 2.536 ± 0.024	2.365PheGlu: 2.365 ± 0.021	1.677PhePhe: 1.677 ± 0.024	2.534PheGly: 2.534 ± 0.032	0.907PheHis: 0.907 ± 0.013	2.318PheIle: 2.318 ± 0.022	2.143PheLys: 2.143 ± 0.022	3.367PheLeu: 3.367 ± 0.03	1.026PheMet: 1.026 ± 0.014	1.891PheAsn: 1.891 ± 0.018	1.57PhePro: 1.57 ± 0.019	1.537PheGln: 1.537 ± 0.016	1.621PheArg: 1.621 ± 0.019	3.115PheSer: 3.115 ± 0.026	2.227PheThr: 2.227 ± 0.022	2.577PheVal: 2.577 ± 0.027	0.521PheTrp: 0.521 ± 0.011	1.429PheTyr: 1.429 ± 0.016	0.001PheXaa: 0.001 ± 0.0
Gly	3.337GlyAla: 3.337 ± 0.033	0.736GlyCys: 0.736 ± 0.014	2.726GlyAsp: 2.726 ± 0.029	2.51GlyGlu: 2.51 ± 0.025	2.351GlyPhe: 2.351 ± 0.027	3.796GlyGly: 3.796 ± 0.046	1.442GlyHis: 1.442 ± 0.018	3.141GlyIle: 3.141 ± 0.026	3.038GlyLys: 3.038 ± 0.029	4.48GlyLeu: 4.48 ± 0.035	1.185GlyMet: 1.185 ± 0.017	2.356GlyAsn: 2.356 ± 0.026	1.777GlyPro: 1.777 ± 0.022	1.987GlyGln: 1.987 ± 0.024	2.426GlyArg: 2.426 ± 0.028	4.259GlySer: 4.259 ± 0.035	2.847GlyThr: 2.847 ± 0.026	3.198GlyVal: 3.198 ± 0.033	0.713GlyTrp: 0.713 ± 0.014	1.995GlyTyr: 1.995 ± 0.023	0.001GlyXaa: 0.001 ± 0.001
His	1.685HisAla: 1.685 ± 0.018	0.409HisCys: 0.409 ± 0.01	1.392HisAsp: 1.392 ± 0.02	1.298HisGlu: 1.298 ± 0.017	1.022HisPhe: 1.022 ± 0.015	1.342HisGly: 1.342 ± 0.019	1.493HisHis: 1.493 ± 0.029	1.53HisIle: 1.53 ± 0.016	1.273HisLys: 1.273 ± 0.015	2.482HisLeu: 2.482 ± 0.025	0.633HisMet: 0.633 ± 0.012	1.151HisAsn: 1.151 ± 0.016	1.507HisPro: 1.507 ± 0.021	1.707HisGln: 1.707 ± 0.023	1.372HisArg: 1.372 ± 0.017	1.988HisSer: 1.988 ± 0.023	1.49HisThr: 1.49 ± 0.017	1.603HisVal: 1.603 ± 0.018	0.301HisTrp: 0.301 ± 0.008	0.968HisTyr: 0.968 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.322IleAla: 4.322 ± 0.03	0.872IleCys: 0.872 ± 0.015	3.579IleAsp: 3.579 ± 0.03	3.533IleGlu: 3.533 ± 0.026	2.138IlePhe: 2.138 ± 0.024	2.875IleGly: 2.875 ± 0.03	1.602IleHis: 1.602 ± 0.022	3.294IleIle: 3.294 ± 0.03	3.617IleLys: 3.617 ± 0.033	5.016IleLeu: 5.016 ± 0.039	1.448IleMet: 1.448 ± 0.016	2.71IleAsn: 2.71 ± 0.022	3.057IlePro: 3.057 ± 0.023	2.759IleGln: 2.759 ± 0.023	2.791IleArg: 2.791 ± 0.025	4.417IleSer: 4.417 ± 0.032	3.491IleThr: 3.491 ± 0.028	3.671IleVal: 3.671 ± 0.027	0.667IleTrp: 0.667 ± 0.013	1.911IleTyr: 1.911 ± 0.019	0.001IleXaa: 0.001 ± 0.0
Lys	4.316LysAla: 4.316 ± 0.035	0.687LysCys: 0.687 ± 0.012	3.459LysAsp: 3.459 ± 0.031	4.346LysGlu: 4.346 ± 0.04	1.932LysPhe: 1.932 ± 0.019	2.553LysGly: 2.553 ± 0.029	1.557LysHis: 1.557 ± 0.019	3.106LysIle: 3.106 ± 0.028	5.418LysLys: 5.418 ± 0.055	5.299LysLeu: 5.299 ± 0.038	1.481LysMet: 1.481 ± 0.019	2.8LysAsn: 2.8 ± 0.025	2.85LysPro: 2.85 ± 0.028	3.151LysGln: 3.151 ± 0.031	3.845LysArg: 3.845 ± 0.034	4.791LysSer: 4.791 ± 0.039	3.466LysThr: 3.466 ± 0.03	3.347LysVal: 3.347 ± 0.03	0.642LysTrp: 0.642 ± 0.012	2.032LysTyr: 2.032 ± 0.02	0.001LysXaa: 0.001 ± 0.0
Leu	6.333LeuAla: 6.333 ± 0.044	1.305LeuCys: 1.305 ± 0.017	5.312LeuAsp: 5.312 ± 0.037	5.503LeuGlu: 5.503 ± 0.046	3.591LeuPhe: 3.591 ± 0.034	4.573LeuGly: 4.573 ± 0.035	2.198LeuHis: 2.198 ± 0.023	4.768LeuIle: 4.768 ± 0.034	5.531LeuLys: 5.531 ± 0.049	8.559LeuLeu: 8.559 ± 0.058	2.229LeuMet: 2.229 ± 0.02	4.194LeuAsn: 4.194 ± 0.027	4.754LeuPro: 4.754 ± 0.032	4.349LeuGln: 4.349 ± 0.039	4.215LeuArg: 4.215 ± 0.032	7.311LeuSer: 7.311 ± 0.038	4.994LeuThr: 4.994 ± 0.029	5.428LeuVal: 5.428 ± 0.041	0.94LeuTrp: 0.94 ± 0.013	2.859LeuTyr: 2.859 ± 0.024	0.002LeuXaa: 0.002 ± 0.001
Met	1.998MetAla: 1.998 ± 0.022	0.294MetCys: 0.294 ± 0.008	1.665MetAsp: 1.665 ± 0.019	1.551MetGlu: 1.551 ± 0.018	0.895MetPhe: 0.895 ± 0.014	1.249MetGly: 1.249 ± 0.017	0.548MetHis: 0.548 ± 0.011	1.371MetIle: 1.371 ± 0.018	1.394MetLys: 1.394 ± 0.017	2.198MetLeu: 2.198 ± 0.02	0.874MetMet: 0.874 ± 0.017	1.264MetAsn: 1.264 ± 0.016	1.222MetPro: 1.222 ± 0.02	1.096MetGln: 1.096 ± 0.017	1.112MetArg: 1.112 ± 0.015	2.236MetSer: 2.236 ± 0.026	1.6MetThr: 1.6 ± 0.016	1.429MetVal: 1.429 ± 0.016	0.242MetTrp: 0.242 ± 0.006	0.768MetTyr: 0.768 ± 0.014	0.001MetXaa: 0.001 ± 0.0
Asn	3.62AsnAla: 3.62 ± 0.027	0.584AsnCys: 0.584 ± 0.011	2.906AsnAsp: 2.906 ± 0.027	2.874AsnGlu: 2.874 ± 0.026	1.593AsnPhe: 1.593 ± 0.017	2.654AsnGly: 2.654 ± 0.028	1.296AsnHis: 1.296 ± 0.016	2.825AsnIle: 2.825 ± 0.025	2.874AsnLys: 2.874 ± 0.026	3.782AsnLeu: 3.782 ± 0.03	1.333AsnMet: 1.333 ± 0.018	3.34AsnAsn: 3.34 ± 0.041	2.243AsnPro: 2.243 ± 0.021	2.226AsnGln: 2.226 ± 0.021	2.145AsnArg: 2.145 ± 0.024	3.892AsnSer: 3.892 ± 0.032	3.364AsnThr: 3.364 ± 0.03	2.928AsnVal: 2.928 ± 0.029	0.545AsnTrp: 0.545 ± 0.012	1.63AsnTyr: 1.63 ± 0.016	0.001AsnXaa: 0.001 ± 0.0
Pro	3.535ProAla: 3.535 ± 0.03	0.481ProCys: 0.481 ± 0.011	2.376ProAsp: 2.376 ± 0.025	2.856ProGlu: 2.856 ± 0.026	1.901ProPhe: 1.901 ± 0.02	2.006ProGly: 2.006 ± 0.025	1.258ProHis: 1.258 ± 0.019	2.761ProIle: 2.761 ± 0.027	2.633ProLys: 2.633 ± 0.026	4.19ProLeu: 4.19 ± 0.032	1.08ProMet: 1.08 ± 0.018	2.369ProAsn: 2.369 ± 0.024	3.967ProPro: 3.967 ± 0.067	2.268ProGln: 2.268 ± 0.027	1.97ProArg: 1.97 ± 0.023	5.127ProSer: 5.127 ± 0.043	3.683ProThr: 3.683 ± 0.031	3.037ProVal: 3.037 ± 0.033	0.44ProTrp: 0.44 ± 0.009	1.52ProTyr: 1.52 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.107GlnAla: 3.107 ± 0.034	0.549GlnCys: 0.549 ± 0.012	2.743GlnAsp: 2.743 ± 0.025	3.054GlnGlu: 3.054 ± 0.03	1.679GlnPhe: 1.679 ± 0.017	1.933GlnGly: 1.933 ± 0.018	1.891GlnHis: 1.891 ± 0.024	2.345GlnIle: 2.345 ± 0.023	2.832GlnLys: 2.832 ± 0.025	4.465GlnLeu: 4.465 ± 0.039	1.135GlnMet: 1.135 ± 0.016	1.905GlnAsn: 1.905 ± 0.02	2.524GlnPro: 2.524 ± 0.028	6.852GlnGln: 6.852 ± 0.136	2.378GlnArg: 2.378 ± 0.02	3.358GlnSer: 3.358 ± 0.028	2.348GlnThr: 2.348 ± 0.023	2.672GlnVal: 2.672 ± 0.025	0.512GlnTrp: 0.512 ± 0.01	1.506GlnTyr: 1.506 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	2.992ArgAla: 2.992 ± 0.03	0.61ArgCys: 0.61 ± 0.013	2.471ArgAsp: 2.471 ± 0.026	2.736ArgGlu: 2.736 ± 0.028	1.935ArgPhe: 1.935 ± 0.02	2.285ArgGly: 2.285 ± 0.03	1.431ArgHis: 1.431 ± 0.018	2.832ArgIle: 2.832 ± 0.023	3.397ArgLys: 3.397 ± 0.028	4.584ArgLeu: 4.584 ± 0.039	1.196ArgMet: 1.196 ± 0.016	2.276ArgAsn: 2.276 ± 0.021	2.209ArgPro: 2.209 ± 0.02	2.405ArgGln: 2.405 ± 0.024	3.37ArgArg: 3.37 ± 0.039	3.817ArgSer: 3.817 ± 0.034	2.406ArgThr: 2.406 ± 0.02	2.623ArgVal: 2.623 ± 0.025	0.576ArgTrp: 0.576 ± 0.009	1.65ArgTyr: 1.65 ± 0.02	0.001ArgXaa: 0.001 ± 0.0
Ser	5.778SerAla: 5.778 ± 0.043	0.983SerCys: 0.983 ± 0.015	4.2SerAsp: 4.2 ± 0.036	3.885SerGlu: 3.885 ± 0.032	3.294SerPhe: 3.294 ± 0.026	3.962SerGly: 3.962 ± 0.037	1.968SerHis: 1.968 ± 0.022	5.023SerIle: 5.023 ± 0.033	4.793SerLys: 4.793 ± 0.036	7.128SerLeu: 7.128 ± 0.046	1.984SerMet: 1.984 ± 0.022	4.714SerAsn: 4.714 ± 0.034	4.586SerPro: 4.586 ± 0.047	3.327SerGln: 3.327 ± 0.029	3.854SerArg: 3.854 ± 0.032	10.62SerSer: 10.62 ± 0.098	6.446SerThr: 6.446 ± 0.053	4.724SerVal: 4.724 ± 0.031	0.848SerTrp: 0.848 ± 0.012	2.376SerTyr: 2.376 ± 0.024	0.001SerXaa: 0.001 ± 0.0
Thr	5.149ThrAla: 5.149 ± 0.036	0.835ThrCys: 0.835 ± 0.014	3.044ThrAsp: 3.044 ± 0.024	3.301ThrGlu: 3.301 ± 0.029	2.359ThrPhe: 2.359 ± 0.023	3.111ThrGly: 3.111 ± 0.031	1.504ThrHis: 1.504 ± 0.016	3.727ThrIle: 3.727 ± 0.03	3.396ThrLys: 3.396 ± 0.03	5.495ThrLeu: 5.495 ± 0.036	1.408ThrMet: 1.408 ± 0.014	2.986ThrAsn: 2.986 ± 0.026	3.688ThrPro: 3.688 ± 0.035	2.29ThrGln: 2.29 ± 0.021	2.557ThrArg: 2.557 ± 0.021	5.92ThrSer: 5.92 ± 0.052	5.819ThrThr: 5.819 ± 0.063	3.814ThrVal: 3.814 ± 0.031	0.633ThrTrp: 0.633 ± 0.013	1.7ThrTyr: 1.7 ± 0.02	0.001ThrXaa: 0.001 ± 0.0
Val	4.464ValAla: 4.464 ± 0.031	0.909ValCys: 0.909 ± 0.013	3.824ValAsp: 3.824 ± 0.032	3.6ValGlu: 3.6 ± 0.031	2.487ValPhe: 2.487 ± 0.025	3.044ValGly: 3.044 ± 0.032	1.455ValHis: 1.455 ± 0.018	3.55ValIle: 3.55 ± 0.029	3.482ValLys: 3.482 ± 0.029	5.465ValLeu: 5.465 ± 0.037	1.491ValMet: 1.491 ± 0.017	2.801ValAsn: 2.801 ± 0.025	2.964ValPro: 2.964 ± 0.027	2.444ValGln: 2.444 ± 0.023	2.624ValArg: 2.624 ± 0.024	4.528ValSer: 4.528 ± 0.033	3.272ValThr: 3.272 ± 0.035	4.01ValVal: 4.01 ± 0.033	0.669ValTrp: 0.669 ± 0.012	2.095ValTyr: 2.095 ± 0.02	0.002ValXaa: 0.002 ± 0.001
Trp	0.662TrpAla: 0.662 ± 0.012	0.198TrpCys: 0.198 ± 0.006	0.684TrpAsp: 0.684 ± 0.014	0.584TrpGlu: 0.584 ± 0.011	0.516TrpPhe: 0.516 ± 0.012	0.555TrpGly: 0.555 ± 0.01	0.296TrpHis: 0.296 ± 0.008	0.748TrpIle: 0.748 ± 0.014	0.75TrpLys: 0.75 ± 0.012	1.016TrpLeu: 1.016 ± 0.016	0.323TrpMet: 0.323 ± 0.009	0.586TrpAsn: 0.586 ± 0.011	0.381TrpPro: 0.381 ± 0.009	0.455TrpGln: 0.455 ± 0.01	0.62TrpArg: 0.62 ± 0.011	0.888TrpSer: 0.888 ± 0.015	0.683TrpThr: 0.683 ± 0.012	0.614TrpVal: 0.614 ± 0.011	0.185TrpTrp: 0.185 ± 0.006	0.378TrpTyr: 0.378 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.086TyrAla: 2.086 ± 0.022	0.619TyrCys: 0.619 ± 0.013	1.963TyrAsp: 1.963 ± 0.021	1.761TyrGlu: 1.761 ± 0.021	1.484TyrPhe: 1.484 ± 0.018	1.892TyrGly: 1.892 ± 0.023	0.991TyrHis: 0.991 ± 0.016	1.87TyrIle: 1.87 ± 0.019	1.822TyrLys: 1.822 ± 0.021	3.111TyrLeu: 3.111 ± 0.025	0.863TyrMet: 0.863 ± 0.013	1.723TyrAsn: 1.723 ± 0.018	1.499TyrPro: 1.499 ± 0.019	1.634TyrGln: 1.634 ± 0.02	1.652TyrArg: 1.652 ± 0.019	2.448TyrSer: 2.448 ± 0.025	1.914TyrThr: 1.914 ± 0.017	1.801TyrVal: 1.801 ± 0.021	0.404TyrTrp: 0.404 ± 0.009	1.432TyrTyr: 1.432 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.001XaaMet: 0.001 ± 0.001	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.002XaaThr: 0.002 ± 0.001	0.001XaaVal: 0.001 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.031XaaXaa: 0.031 ± 0.013

Statistics based on 11311 proteins (5257899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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