Amino acid dipepetide frequency for Thioflavicoccus mobilis 8321

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.33AlaAla: 16.33 ± 0.198	1.254AlaCys: 1.254 ± 0.038	6.906AlaAsp: 6.906 ± 0.083	8.584AlaGlu: 8.584 ± 0.117	3.78AlaPhe: 3.78 ± 0.053	9.953AlaGly: 9.953 ± 0.115	2.37AlaHis: 2.37 ± 0.048	5.804AlaIle: 5.804 ± 0.073	2.991AlaLys: 2.991 ± 0.058	13.972AlaLeu: 13.972 ± 0.152	2.77AlaMet: 2.77 ± 0.049	2.611AlaAsn: 2.611 ± 0.061	5.552AlaPro: 5.552 ± 0.088	4.024AlaGln: 4.024 ± 0.065	9.72AlaArg: 9.72 ± 0.127	5.47AlaSer: 5.47 ± 0.077	5.819AlaThr: 5.819 ± 0.074	8.486AlaVal: 8.486 ± 0.107	1.691AlaTrp: 1.691 ± 0.042	2.402AlaTyr: 2.402 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	1.068CysAla: 1.068 ± 0.033	0.154CysCys: 0.154 ± 0.012	0.613CysAsp: 0.613 ± 0.025	0.591CysGlu: 0.591 ± 0.027	0.327CysPhe: 0.327 ± 0.017	1.054CysGly: 1.054 ± 0.029	0.371CysHis: 0.371 ± 0.024	0.411CysIle: 0.411 ± 0.019	0.202CysLys: 0.202 ± 0.013	1.041CysLeu: 1.041 ± 0.032	0.163CysMet: 0.163 ± 0.012	0.257CysAsn: 0.257 ± 0.016	0.665CysPro: 0.665 ± 0.03	0.313CysGln: 0.313 ± 0.018	0.946CysArg: 0.946 ± 0.032	0.498CysSer: 0.498 ± 0.025	0.502CysThr: 0.502 ± 0.023	0.657CysVal: 0.657 ± 0.027	0.131CysTrp: 0.131 ± 0.011	0.255CysTyr: 0.255 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.539AspAla: 6.539 ± 0.086	0.648AspCys: 0.648 ± 0.024	3.397AspAsp: 3.397 ± 0.069	4.247AspGlu: 4.247 ± 0.063	2.113AspPhe: 2.113 ± 0.05	5.429AspGly: 5.429 ± 0.096	1.258AspHis: 1.258 ± 0.033	2.481AspIle: 2.481 ± 0.052	1.414AspLys: 1.414 ± 0.043	7.15AspLeu: 7.15 ± 0.091	1.093AspMet: 1.093 ± 0.032	1.283AspAsn: 1.283 ± 0.037	3.885AspPro: 3.885 ± 0.064	2.027AspGln: 2.027 ± 0.047	4.53AspArg: 4.53 ± 0.072	2.34AspSer: 2.34 ± 0.049	2.492AspThr: 2.492 ± 0.06	3.546AspVal: 3.546 ± 0.062	1.228AspTrp: 1.228 ± 0.034	1.81AspTyr: 1.81 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	7.946GluAla: 7.946 ± 0.125	0.446GluCys: 0.446 ± 0.022	3.121GluAsp: 3.121 ± 0.055	3.671GluGlu: 3.671 ± 0.067	1.478GluPhe: 1.478 ± 0.038	4.31GluGly: 4.31 ± 0.057	1.525GluHis: 1.525 ± 0.046	3.387GluIle: 3.387 ± 0.058	1.64GluLys: 1.64 ± 0.042	6.93GluLeu: 6.93 ± 0.088	1.35GluMet: 1.35 ± 0.037	1.24GluAsn: 1.24 ± 0.034	3.398GluPro: 3.398 ± 0.065	2.829GluGln: 2.829 ± 0.051	7.137GluArg: 7.137 ± 0.114	2.733GluSer: 2.733 ± 0.057	3.485GluThr: 3.485 ± 0.058	4.697GluVal: 4.697 ± 0.08	0.696GluTrp: 0.696 ± 0.026	1.14GluTyr: 1.14 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.993PheAla: 3.993 ± 0.061	0.392PheCys: 0.392 ± 0.02	2.37PheAsp: 2.37 ± 0.05	2.116PheGlu: 2.116 ± 0.043	1.367PhePhe: 1.367 ± 0.042	2.981PheGly: 2.981 ± 0.052	0.733PheHis: 0.733 ± 0.023	1.443PheIle: 1.443 ± 0.037	0.765PheLys: 0.765 ± 0.031	3.372PheLeu: 3.372 ± 0.066	0.592PheMet: 0.592 ± 0.024	0.869PheAsn: 0.869 ± 0.029	1.52PhePro: 1.52 ± 0.037	1.012PheGln: 1.012 ± 0.031	2.21PheArg: 2.21 ± 0.047	1.922PheSer: 1.922 ± 0.041	1.71PheThr: 1.71 ± 0.038	2.574PheVal: 2.574 ± 0.048	0.484PheTrp: 0.484 ± 0.025	0.929PheTyr: 0.929 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	8.426GlyAla: 8.426 ± 0.112	1.061GlyCys: 1.061 ± 0.034	4.803GlyAsp: 4.803 ± 0.071	5.444GlyGlu: 5.444 ± 0.084	3.006GlyPhe: 3.006 ± 0.058	6.86GlyGly: 6.86 ± 0.099	2.031GlyHis: 2.031 ± 0.047	4.232GlyIle: 4.232 ± 0.074	2.258GlyLys: 2.258 ± 0.054	9.772GlyLeu: 9.772 ± 0.114	1.864GlyMet: 1.864 ± 0.045	1.862GlyAsn: 1.862 ± 0.049	3.615GlyPro: 3.615 ± 0.061	2.905GlyGln: 2.905 ± 0.045	7.018GlyArg: 7.018 ± 0.088	4.066GlySer: 4.066 ± 0.071	4.15GlyThr: 4.15 ± 0.071	6.048GlyVal: 6.048 ± 0.072	1.4GlyTrp: 1.4 ± 0.036	2.46GlyTyr: 2.46 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.263HisAla: 2.263 ± 0.046	0.319HisCys: 0.319 ± 0.017	1.23HisAsp: 1.23 ± 0.035	1.234HisGlu: 1.234 ± 0.036	0.829HisPhe: 0.829 ± 0.026	2.044HisGly: 2.044 ± 0.043	0.681HisHis: 0.681 ± 0.025	0.853HisIle: 0.853 ± 0.029	0.462HisLys: 0.462 ± 0.019	2.671HisLeu: 2.671 ± 0.048	0.401HisMet: 0.401 ± 0.02	0.491HisAsn: 0.491 ± 0.024	1.578HisPro: 1.578 ± 0.037	0.843HisGln: 0.843 ± 0.031	2.067HisArg: 2.067 ± 0.049	0.986HisSer: 0.986 ± 0.03	0.913HisThr: 0.913 ± 0.032	1.405HisVal: 1.405 ± 0.035	0.448HisTrp: 0.448 ± 0.017	0.666HisTyr: 0.666 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.581IleAla: 6.581 ± 0.097	0.458IleCys: 0.458 ± 0.019	3.586IleAsp: 3.586 ± 0.058	3.745IleGlu: 3.745 ± 0.064	1.33IlePhe: 1.33 ± 0.039	4.474IleGly: 4.474 ± 0.063	1.098IleHis: 1.098 ± 0.032	1.693IleIle: 1.693 ± 0.044	1.232IleLys: 1.232 ± 0.038	4.533IleLeu: 4.533 ± 0.068	0.708IleMet: 0.708 ± 0.029	1.206IleAsn: 1.206 ± 0.035	2.414IlePro: 2.414 ± 0.043	1.459IleGln: 1.459 ± 0.037	3.36IleArg: 3.36 ± 0.052	2.1IleSer: 2.1 ± 0.046	2.183IleThr: 2.183 ± 0.046	3.355IleVal: 3.355 ± 0.057	0.539IleTrp: 0.539 ± 0.023	1.086IleTyr: 1.086 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	2.979LysAla: 2.979 ± 0.065	0.176LysCys: 0.176 ± 0.014	1.417LysAsp: 1.417 ± 0.039	1.5LysGlu: 1.5 ± 0.042	0.529LysPhe: 0.529 ± 0.022	2.087LysGly: 2.087 ± 0.047	0.491LysHis: 0.491 ± 0.021	1.17LysIle: 1.17 ± 0.033	0.902LysLys: 0.902 ± 0.041	2.389LysLeu: 2.389 ± 0.052	0.492LysMet: 0.492 ± 0.02	0.586LysAsn: 0.586 ± 0.025	1.405LysPro: 1.405 ± 0.041	0.901LysGln: 0.901 ± 0.027	2.147LysArg: 2.147 ± 0.048	1.242LysSer: 1.242 ± 0.029	1.517LysThr: 1.517 ± 0.041	1.909LysVal: 1.909 ± 0.048	0.262LysTrp: 0.262 ± 0.016	0.568LysTyr: 0.568 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	16.082LeuAla: 16.082 ± 0.167	1.077LeuCys: 1.077 ± 0.031	6.965LeuAsp: 6.965 ± 0.09	6.675LeuGlu: 6.675 ± 0.084	3.918LeuPhe: 3.918 ± 0.059	9.285LeuGly: 9.285 ± 0.109	2.369LeuHis: 2.369 ± 0.048	5.544LeuIle: 5.544 ± 0.085	2.779LeuLys: 2.779 ± 0.051	12.035LeuLeu: 12.035 ± 0.141	2.247LeuMet: 2.247 ± 0.055	2.304LeuAsn: 2.304 ± 0.051	6.126LeuPro: 6.126 ± 0.085	3.188LeuGln: 3.188 ± 0.059	8.914LeuArg: 8.914 ± 0.098	5.764LeuSer: 5.764 ± 0.085	5.755LeuThr: 5.755 ± 0.083	8.719LeuVal: 8.719 ± 0.107	1.442LeuTrp: 1.442 ± 0.047	2.395LeuTyr: 2.395 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.501MetAla: 2.501 ± 0.051	0.131MetCys: 0.131 ± 0.01	1.069MetAsp: 1.069 ± 0.033	1.023MetGlu: 1.023 ± 0.029	0.486MetPhe: 0.486 ± 0.021	1.477MetGly: 1.477 ± 0.038	0.392MetHis: 0.392 ± 0.02	0.987MetIle: 0.987 ± 0.031	0.758MetLys: 0.758 ± 0.028	2.13MetLeu: 2.13 ± 0.049	0.453MetMet: 0.453 ± 0.023	0.603MetAsn: 0.603 ± 0.024	1.249MetPro: 1.249 ± 0.034	0.752MetGln: 0.752 ± 0.028	1.615MetArg: 1.615 ± 0.034	1.341MetSer: 1.341 ± 0.035	1.375MetThr: 1.375 ± 0.037	1.36MetVal: 1.36 ± 0.036	0.135MetTrp: 0.135 ± 0.01	0.309MetTyr: 0.309 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.493AsnAla: 2.493 ± 0.052	0.259AsnCys: 0.259 ± 0.016	1.291AsnAsp: 1.291 ± 0.036	1.233AsnGlu: 1.233 ± 0.031	0.722AsnPhe: 0.722 ± 0.029	1.937AsnGly: 1.937 ± 0.045	0.493AsnHis: 0.493 ± 0.02	1.053AsnIle: 1.053 ± 0.037	0.572AsnLys: 0.572 ± 0.025	2.662AsnLeu: 2.662 ± 0.057	0.474AsnMet: 0.474 ± 0.021	0.541AsnAsn: 0.541 ± 0.024	1.657AsnPro: 1.657 ± 0.039	0.757AsnGln: 0.757 ± 0.027	1.876AsnArg: 1.876 ± 0.043	0.944AsnSer: 0.944 ± 0.031	0.988AsnThr: 0.988 ± 0.037	1.457AsnVal: 1.457 ± 0.038	0.377AsnTrp: 0.377 ± 0.022	0.584AsnTyr: 0.584 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	6.396ProAla: 6.396 ± 0.101	0.453ProCys: 0.453 ± 0.023	3.658ProAsp: 3.658 ± 0.057	4.058ProGlu: 4.058 ± 0.064	1.86ProPhe: 1.86 ± 0.043	4.894ProGly: 4.894 ± 0.076	1.076ProHis: 1.076 ± 0.035	2.415ProIle: 2.415 ± 0.046	1.31ProLys: 1.31 ± 0.039	5.66ProLeu: 5.66 ± 0.077	1.037ProMet: 1.037 ± 0.03	1.248ProAsn: 1.248 ± 0.036	3.255ProPro: 3.255 ± 0.076	1.849ProGln: 1.849 ± 0.042	3.632ProArg: 3.632 ± 0.058	2.942ProSer: 2.942 ± 0.051	2.669ProThr: 2.669 ± 0.05	4.14ProVal: 4.14 ± 0.067	0.84ProTrp: 0.84 ± 0.029	1.278ProTyr: 1.278 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	4.669GlnAla: 4.669 ± 0.075	0.303GlnCys: 0.303 ± 0.017	1.673GlnAsp: 1.673 ± 0.037	1.766GlnGlu: 1.766 ± 0.043	1.014GlnPhe: 1.014 ± 0.035	2.799GlnGly: 2.799 ± 0.054	0.719GlnHis: 0.719 ± 0.026	1.87GlnIle: 1.87 ± 0.041	0.713GlnLys: 0.713 ± 0.027	3.538GlnLeu: 3.538 ± 0.059	0.752GlnMet: 0.752 ± 0.024	0.647GlnAsn: 0.647 ± 0.023	1.838GlnPro: 1.838 ± 0.042	1.422GlnGln: 1.422 ± 0.043	3.335GlnArg: 3.335 ± 0.064	1.515GlnSer: 1.515 ± 0.037	1.652GlnThr: 1.652 ± 0.048	2.934GlnVal: 2.934 ± 0.051	0.465GlnTrp: 0.465 ± 0.023	0.676GlnTyr: 0.676 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	8.595ArgAla: 8.595 ± 0.118	0.873ArgCys: 0.873 ± 0.034	4.63ArgAsp: 4.63 ± 0.06	5.127ArgGlu: 5.127 ± 0.082	3.358ArgPhe: 3.358 ± 0.061	5.499ArgGly: 5.499 ± 0.082	2.267ArgHis: 2.267 ± 0.042	4.342ArgIle: 4.342 ± 0.053	1.792ArgLys: 1.792 ± 0.046	10.976ArgLeu: 10.976 ± 0.127	1.688ArgMet: 1.688 ± 0.033	1.75ArgAsn: 1.75 ± 0.041	4.438ArgPro: 4.438 ± 0.07	3.248ArgGln: 3.248 ± 0.062	8.023ArgArg: 8.023 ± 0.106	3.615ArgSer: 3.615 ± 0.062	3.665ArgThr: 3.665 ± 0.062	5.772ArgVal: 5.772 ± 0.069	1.386ArgTrp: 1.386 ± 0.043	2.34ArgTyr: 2.34 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	5.371SerAla: 5.371 ± 0.067	0.493SerCys: 0.493 ± 0.025	2.814SerAsp: 2.814 ± 0.056	2.666SerGlu: 2.666 ± 0.052	1.757SerPhe: 1.757 ± 0.037	4.91SerGly: 4.91 ± 0.08	1.045SerHis: 1.045 ± 0.034	2.209SerIle: 2.209 ± 0.042	1.142SerLys: 1.142 ± 0.033	5.467SerLeu: 5.467 ± 0.084	0.986SerMet: 0.986 ± 0.028	1.153SerAsn: 1.153 ± 0.031	2.964SerPro: 2.964 ± 0.055	1.561SerGln: 1.561 ± 0.041	3.62SerArg: 3.62 ± 0.063	2.506SerSer: 2.506 ± 0.06	2.288SerThr: 2.288 ± 0.051	3.257SerVal: 3.257 ± 0.048	0.686SerTrp: 0.686 ± 0.027	1.146SerTyr: 1.146 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.66ThrAla: 5.66 ± 0.072	0.499ThrCys: 0.499 ± 0.023	2.755ThrAsp: 2.755 ± 0.051	2.826ThrGlu: 2.826 ± 0.053	1.637ThrPhe: 1.637 ± 0.045	4.58ThrGly: 4.58 ± 0.074	1.076ThrHis: 1.076 ± 0.031	2.332ThrIle: 2.332 ± 0.05	1.146ThrLys: 1.146 ± 0.031	6.215ThrLeu: 6.215 ± 0.089	0.932ThrMet: 0.932 ± 0.028	1.11ThrAsn: 1.11 ± 0.035	3.216ThrPro: 3.216 ± 0.056	1.45ThrGln: 1.45 ± 0.035	3.659ThrArg: 3.659 ± 0.059	2.411ThrSer: 2.411 ± 0.046	2.624ThrThr: 2.624 ± 0.054	3.593ThrVal: 3.593 ± 0.058	0.636ThrTrp: 0.636 ± 0.028	1.121ThrTyr: 1.121 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	9.051ValAla: 9.051 ± 0.103	0.736ValCys: 0.736 ± 0.026	4.41ValAsp: 4.41 ± 0.07	4.581ValGlu: 4.581 ± 0.069	2.486ValPhe: 2.486 ± 0.052	5.68ValGly: 5.68 ± 0.087	1.489ValHis: 1.489 ± 0.038	3.427ValIle: 3.427 ± 0.064	1.724ValLys: 1.724 ± 0.043	7.898ValLeu: 7.898 ± 0.095	1.441ValMet: 1.441 ± 0.033	1.736ValAsn: 1.736 ± 0.043	3.797ValPro: 3.797 ± 0.063	2.172ValGln: 2.172 ± 0.042	5.586ValArg: 5.586 ± 0.074	3.674ValSer: 3.674 ± 0.058	4.033ValThr: 4.033 ± 0.077	5.789ValVal: 5.789 ± 0.091	0.873ValTrp: 0.873 ± 0.03	1.634ValTyr: 1.634 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.221TrpAla: 1.221 ± 0.036	0.179TrpCys: 0.179 ± 0.011	0.766TrpAsp: 0.766 ± 0.031	0.716TrpGlu: 0.716 ± 0.025	0.434TrpPhe: 0.434 ± 0.021	1.008TrpGly: 1.008 ± 0.033	0.393TrpHis: 0.393 ± 0.021	0.624TrpIle: 0.624 ± 0.025	0.324TrpLys: 0.324 ± 0.018	2.156TrpLeu: 2.156 ± 0.056	0.312TrpMet: 0.312 ± 0.019	0.323TrpAsn: 0.323 ± 0.019	0.82TrpPro: 0.82 ± 0.028	0.661TrpGln: 0.661 ± 0.026	1.44TrpArg: 1.44 ± 0.037	0.809TrpSer: 0.809 ± 0.028	0.642TrpThr: 0.642 ± 0.024	0.969TrpVal: 0.969 ± 0.034	0.226TrpTrp: 0.226 ± 0.016	0.325TrpTyr: 0.325 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.324TyrAla: 2.324 ± 0.041	0.309TyrCys: 0.309 ± 0.018	1.438TyrAsp: 1.438 ± 0.043	1.356TyrGlu: 1.356 ± 0.033	0.925TyrPhe: 0.925 ± 0.034	2.019TyrGly: 2.019 ± 0.049	0.509TyrHis: 0.509 ± 0.02	0.863TyrIle: 0.863 ± 0.028	0.543TyrLys: 0.543 ± 0.021	3.015TyrLeu: 3.015 ± 0.066	0.39TyrMet: 0.39 ± 0.019	0.548TyrAsn: 0.548 ± 0.022	1.28TyrPro: 1.28 ± 0.035	0.925TyrGln: 0.925 ± 0.032	2.55TyrArg: 2.55 ± 0.047	1.163TyrSer: 1.163 ± 0.03	1.016TyrThr: 1.016 ± 0.033	1.55TyrVal: 1.55 ± 0.048	0.401TyrTrp: 0.401 ± 0.022	0.737TyrTyr: 0.737 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3528 proteins (1133450 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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