Amino acid dipepetide frequency for Pistacia emaravirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.129AlaAla: 1.129 ± 0.459
0.941AlaCys: 0.941 ± 0.3
1.694AlaAsp: 1.694 ± 0.422
0.941AlaGlu: 0.941 ± 0.407
2.07AlaPhe: 2.07 ± 0.427
1.882AlaGly: 1.882 ± 0.567
0.565AlaHis: 0.565 ± 0.207
5.082AlaIle: 5.082 ± 0.593
3.576AlaLys: 3.576 ± 0.697
1.694AlaLeu: 1.694 ± 0.808
1.506AlaMet: 1.506 ± 0.497
2.07AlaAsn: 2.07 ± 0.583
0.753AlaPro: 0.753 ± 0.315
0.941AlaGln: 0.941 ± 0.463
1.506AlaArg: 1.506 ± 0.414
4.517AlaSer: 4.517 ± 0.72
2.259AlaThr: 2.259 ± 0.773
1.129AlaVal: 1.129 ± 0.309
0.0AlaTrp: 0.0 ± 0.0
2.07AlaTyr: 2.07 ± 0.321
0.0AlaXaa: 0.0 ± 0.0
Cys
0.565CysAla: 0.565 ± 0.423
0.0CysCys: 0.0 ± 0.0
1.129CysAsp: 1.129 ± 0.551
1.694CysGlu: 1.694 ± 0.377
1.318CysPhe: 1.318 ± 0.494
0.941CysGly: 0.941 ± 0.643
0.188CysHis: 0.188 ± 0.109
0.753CysIle: 0.753 ± 0.211
1.129CysLys: 1.129 ± 0.377
2.447CysLeu: 2.447 ± 0.73
0.753CysMet: 0.753 ± 0.285
0.941CysAsn: 0.941 ± 0.36
0.941CysPro: 0.941 ± 0.337
0.565CysGln: 0.565 ± 0.222
0.376CysArg: 0.376 ± 0.191
1.129CysSer: 1.129 ± 0.249
1.129CysThr: 1.129 ± 0.273
1.506CysVal: 1.506 ± 0.545
0.0CysTrp: 0.0 ± 0.0
0.941CysTyr: 0.941 ± 0.251
0.0CysXaa: 0.0 ± 0.0
Asp
2.07AspAla: 2.07 ± 0.473
2.07AspCys: 2.07 ± 0.73
5.082AspAsp: 5.082 ± 0.699
3.953AspGlu: 3.953 ± 0.536
2.635AspPhe: 2.635 ± 0.824
1.506AspGly: 1.506 ± 0.617
1.506AspHis: 1.506 ± 0.4
7.905AspIle: 7.905 ± 0.868
2.823AspLys: 2.823 ± 0.685
6.023AspLeu: 6.023 ± 1.268
2.07AspMet: 2.07 ± 0.536
3.576AspAsn: 3.576 ± 0.28
2.07AspPro: 2.07 ± 0.606
1.694AspGln: 1.694 ± 0.306
1.882AspArg: 1.882 ± 0.526
4.141AspSer: 4.141 ± 0.442
4.705AspThr: 4.705 ± 1.197
3.953AspVal: 3.953 ± 0.542
0.188AspTrp: 0.188 ± 0.201
3.764AspTyr: 3.764 ± 0.544
0.0AspXaa: 0.0 ± 0.0
Glu
3.011GluAla: 3.011 ± 0.855
1.318GluCys: 1.318 ± 0.62
3.576GluAsp: 3.576 ± 1.053
2.447GluGlu: 2.447 ± 0.403
4.517GluPhe: 4.517 ± 0.733
1.506GluGly: 1.506 ± 0.488
1.694GluHis: 1.694 ± 0.346
7.34GluIle: 7.34 ± 1.765
6.211GluLys: 6.211 ± 0.625
6.964GluLeu: 6.964 ± 1.202
1.694GluMet: 1.694 ± 0.466
3.388GluAsn: 3.388 ± 0.505
0.941GluPro: 0.941 ± 0.363
0.941GluGln: 0.941 ± 0.51
2.259GluArg: 2.259 ± 0.587
3.764GluSer: 3.764 ± 0.938
2.635GluThr: 2.635 ± 0.537
2.447GluVal: 2.447 ± 0.343
0.188GluTrp: 0.188 ± 0.109
3.388GluTyr: 3.388 ± 0.531
0.0GluXaa: 0.0 ± 0.0
Phe
1.318PheAla: 1.318 ± 0.443
0.941PheCys: 0.941 ± 0.332
2.447PheAsp: 2.447 ± 0.926
2.635PheGlu: 2.635 ± 0.563
1.506PhePhe: 1.506 ± 0.407
1.694PheGly: 1.694 ± 0.657
1.129PheHis: 1.129 ± 0.275
4.517PheIle: 4.517 ± 0.734
4.329PheLys: 4.329 ± 0.929
4.141PheLeu: 4.141 ± 0.778
1.506PheMet: 1.506 ± 0.346
4.894PheAsn: 4.894 ± 0.485
1.882PhePro: 1.882 ± 0.687
0.565PheGln: 0.565 ± 0.349
1.694PheArg: 1.694 ± 0.244
4.141PheSer: 4.141 ± 1.356
2.447PheThr: 2.447 ± 0.642
1.318PheVal: 1.318 ± 0.363
0.0PheTrp: 0.0 ± 0.0
3.764PheTyr: 3.764 ± 0.405
0.0PheXaa: 0.0 ± 0.0
Gly
0.941GlyAla: 0.941 ± 0.431
0.941GlyCys: 0.941 ± 0.611
2.07GlyAsp: 2.07 ± 0.712
1.318GlyGlu: 1.318 ± 0.258
1.129GlyPhe: 1.129 ± 0.213
0.376GlyGly: 0.376 ± 0.258
0.565GlyHis: 0.565 ± 0.222
1.882GlyIle: 1.882 ± 0.528
2.259GlyLys: 2.259 ± 0.692
2.635GlyLeu: 2.635 ± 0.65
0.941GlyMet: 0.941 ± 0.402
3.764GlyAsn: 3.764 ± 1.042
1.506GlyPro: 1.506 ± 0.516
0.565GlyGln: 0.565 ± 0.232
1.129GlyArg: 1.129 ± 0.39
2.259GlySer: 2.259 ± 0.664
1.506GlyThr: 1.506 ± 0.478
1.506GlyVal: 1.506 ± 0.382
0.0GlyTrp: 0.0 ± 0.0
3.2GlyTyr: 3.2 ± 0.494
0.0GlyXaa: 0.0 ± 0.0
His
0.753HisAla: 0.753 ± 0.322
0.753HisCys: 0.753 ± 0.271
2.07HisAsp: 2.07 ± 0.479
0.753HisGlu: 0.753 ± 0.239
1.318HisPhe: 1.318 ± 0.788
1.318HisGly: 1.318 ± 0.888
0.565HisHis: 0.565 ± 0.222
2.823HisIle: 2.823 ± 0.567
1.694HisLys: 1.694 ± 0.398
2.823HisLeu: 2.823 ± 0.854
1.129HisMet: 1.129 ± 0.401
2.07HisAsn: 2.07 ± 0.538
0.565HisPro: 0.565 ± 0.222
1.318HisGln: 1.318 ± 0.41
0.188HisArg: 0.188 ± 0.191
1.506HisSer: 1.506 ± 0.359
0.376HisThr: 0.376 ± 0.217
0.753HisVal: 0.753 ± 0.288
0.188HisTrp: 0.188 ± 0.109
1.694HisTyr: 1.694 ± 0.288
0.0HisXaa: 0.0 ± 0.0
Ile
3.011IleAla: 3.011 ± 0.867
1.129IleCys: 1.129 ± 0.444
7.529IleAsp: 7.529 ± 0.887
7.152IleGlu: 7.152 ± 0.925
2.635IlePhe: 2.635 ± 0.32
3.011IleGly: 3.011 ± 0.604
2.447IleHis: 2.447 ± 0.425
7.717IleIle: 7.717 ± 0.974
9.787IleLys: 9.787 ± 1.013
7.34IleLeu: 7.34 ± 0.84
2.447IleMet: 2.447 ± 0.489
9.599IleAsn: 9.599 ± 1.237
2.447IlePro: 2.447 ± 0.672
3.764IleGln: 3.764 ± 0.344
4.705IleArg: 4.705 ± 0.667
9.034IleSer: 9.034 ± 1.188
6.964IleThr: 6.964 ± 1.44
4.894IleVal: 4.894 ± 1.07
0.941IleTrp: 0.941 ± 0.455
5.27IleTyr: 5.27 ± 0.808
0.0IleXaa: 0.0 ± 0.0
Lys
3.576LysAla: 3.576 ± 1.099
0.941LysCys: 0.941 ± 0.23
5.082LysAsp: 5.082 ± 0.747
6.023LysGlu: 6.023 ± 1.044
3.2LysPhe: 3.2 ± 0.654
1.318LysGly: 1.318 ± 0.472
2.447LysHis: 2.447 ± 0.901
8.093LysIle: 8.093 ± 0.822
8.846LysLys: 8.846 ± 1.414
7.717LysLeu: 7.717 ± 1.846
1.882LysMet: 1.882 ± 0.645
7.152LysAsn: 7.152 ± 1.167
2.259LysPro: 2.259 ± 0.582
3.011LysGln: 3.011 ± 1.065
3.011LysArg: 3.011 ± 0.587
5.647LysSer: 5.647 ± 1.179
5.835LysThr: 5.835 ± 0.654
4.705LysVal: 4.705 ± 0.818
0.753LysTrp: 0.753 ± 0.271
6.964LysTyr: 6.964 ± 1.131
0.0LysXaa: 0.0 ± 0.0
Leu
3.388LeuAla: 3.388 ± 0.618
2.07LeuCys: 2.07 ± 0.295
4.141LeuAsp: 4.141 ± 1.233
6.588LeuGlu: 6.588 ± 0.767
4.141LeuPhe: 4.141 ± 0.503
2.635LeuGly: 2.635 ± 0.561
3.388LeuHis: 3.388 ± 0.571
9.223LeuIle: 9.223 ± 1.939
9.787LeuLys: 9.787 ± 1.12
7.152LeuLeu: 7.152 ± 2.1
2.259LeuMet: 2.259 ± 0.565
5.27LeuAsn: 5.27 ± 0.801
4.329LeuPro: 4.329 ± 0.907
2.447LeuGln: 2.447 ± 0.663
2.07LeuArg: 2.07 ± 0.666
7.152LeuSer: 7.152 ± 0.505
3.764LeuThr: 3.764 ± 0.906
4.517LeuVal: 4.517 ± 1.16
0.376LeuTrp: 0.376 ± 0.397
3.953LeuTyr: 3.953 ± 0.859
0.0LeuXaa: 0.0 ± 0.0
Met
1.506MetAla: 1.506 ± 0.453
0.188MetCys: 0.188 ± 0.109
2.635MetAsp: 2.635 ± 0.646
1.694MetGlu: 1.694 ± 0.411
0.565MetPhe: 0.565 ± 0.344
0.753MetGly: 0.753 ± 0.377
0.376MetHis: 0.376 ± 0.177
2.447MetIle: 2.447 ± 0.425
2.07MetLys: 2.07 ± 0.394
3.576MetLeu: 3.576 ± 0.838
0.753MetMet: 0.753 ± 0.432
1.506MetAsn: 1.506 ± 0.416
1.129MetPro: 1.129 ± 0.662
0.565MetGln: 0.565 ± 0.326
2.259MetArg: 2.259 ± 0.952
2.07MetSer: 2.07 ± 0.5
2.447MetThr: 2.447 ± 0.564
1.882MetVal: 1.882 ± 0.232
0.0MetTrp: 0.0 ± 0.0
1.694MetTyr: 1.694 ± 0.48
0.0MetXaa: 0.0 ± 0.0
Asn
3.011AsnAla: 3.011 ± 0.644
0.941AsnCys: 0.941 ± 0.315
3.764AsnAsp: 3.764 ± 0.816
5.458AsnGlu: 5.458 ± 1.172
3.576AsnPhe: 3.576 ± 0.814
2.259AsnGly: 2.259 ± 0.688
2.635AsnHis: 2.635 ± 0.459
10.352AsnIle: 10.352 ± 1.358
8.47AsnLys: 8.47 ± 0.776
5.647AsnLeu: 5.647 ± 0.927
2.635AsnMet: 2.635 ± 0.67
3.764AsnAsn: 3.764 ± 0.884
2.07AsnPro: 2.07 ± 0.473
2.447AsnGln: 2.447 ± 0.992
2.635AsnArg: 2.635 ± 0.545
5.082AsnSer: 5.082 ± 0.848
3.2AsnThr: 3.2 ± 0.553
3.388AsnVal: 3.388 ± 0.611
0.565AsnTrp: 0.565 ± 0.28
3.011AsnTyr: 3.011 ± 0.733
0.0AsnXaa: 0.0 ± 0.0
Pro
1.506ProAla: 1.506 ± 0.509
0.753ProCys: 0.753 ± 0.339
1.882ProAsp: 1.882 ± 0.493
2.635ProGlu: 2.635 ± 0.69
1.694ProPhe: 1.694 ± 0.443
1.882ProGly: 1.882 ± 0.294
0.0ProHis: 0.0 ± 0.0
3.2ProIle: 3.2 ± 0.413
1.694ProLys: 1.694 ± 0.529
1.882ProLeu: 1.882 ± 0.404
1.318ProMet: 1.318 ± 0.377
2.635ProAsn: 2.635 ± 0.326
0.941ProPro: 0.941 ± 0.251
0.941ProGln: 0.941 ± 0.409
0.753ProArg: 0.753 ± 0.309
2.07ProSer: 2.07 ± 0.602
2.07ProThr: 2.07 ± 0.541
1.129ProVal: 1.129 ± 0.464
0.0ProTrp: 0.0 ± 0.0
2.07ProTyr: 2.07 ± 0.32
0.0ProXaa: 0.0 ± 0.0
Gln
1.506GlnAla: 1.506 ± 0.481
0.753GlnCys: 0.753 ± 0.473
1.882GlnAsp: 1.882 ± 0.399
1.318GlnGlu: 1.318 ± 0.555
2.259GlnPhe: 2.259 ± 0.827
0.941GlnGly: 0.941 ± 0.251
0.565GlnHis: 0.565 ± 0.254
2.259GlnIle: 2.259 ± 0.592
2.07GlnLys: 2.07 ± 0.462
2.447GlnLeu: 2.447 ± 0.584
1.129GlnMet: 1.129 ± 0.662
2.07GlnAsn: 2.07 ± 0.505
0.565GlnPro: 0.565 ± 0.222
0.565GlnGln: 0.565 ± 0.256
1.129GlnArg: 1.129 ± 0.475
0.941GlnSer: 0.941 ± 0.459
1.694GlnThr: 1.694 ± 0.62
1.129GlnVal: 1.129 ± 0.523
0.188GlnTrp: 0.188 ± 0.198
0.753GlnTyr: 0.753 ± 0.309
0.0GlnXaa: 0.0 ± 0.0
Arg
1.318ArgAla: 1.318 ± 0.651
0.188ArgCys: 0.188 ± 0.191
2.447ArgAsp: 2.447 ± 0.619
2.447ArgGlu: 2.447 ± 0.879
2.07ArgPhe: 2.07 ± 0.469
0.376ArgGly: 0.376 ± 0.177
1.694ArgHis: 1.694 ± 0.395
2.259ArgIle: 2.259 ± 0.474
3.2ArgLys: 3.2 ± 0.687
4.329ArgLeu: 4.329 ± 1.381
0.941ArgMet: 0.941 ± 0.413
1.506ArgAsn: 1.506 ± 0.378
0.753ArgPro: 0.753 ± 0.211
1.129ArgGln: 1.129 ± 0.629
0.376ArgArg: 0.376 ± 0.208
3.388ArgSer: 3.388 ± 0.988
1.506ArgThr: 1.506 ± 0.539
1.318ArgVal: 1.318 ± 0.444
0.0ArgTrp: 0.0 ± 0.0
2.823ArgTyr: 2.823 ± 0.66
0.0ArgXaa: 0.0 ± 0.0
Ser
1.882SerAla: 1.882 ± 0.436
2.07SerCys: 2.07 ± 1.029
5.835SerAsp: 5.835 ± 0.547
2.823SerGlu: 2.823 ± 0.368
6.211SerPhe: 6.211 ± 1.237
2.635SerGly: 2.635 ± 0.686
2.447SerHis: 2.447 ± 0.685
7.717SerIle: 7.717 ± 1.482
6.023SerLys: 6.023 ± 1.327
6.211SerLeu: 6.211 ± 1.142
2.447SerMet: 2.447 ± 0.415
6.399SerAsn: 6.399 ± 0.944
2.259SerPro: 2.259 ± 0.569
1.506SerGln: 1.506 ± 0.484
1.506SerArg: 1.506 ± 0.389
6.211SerSer: 6.211 ± 0.776
4.517SerThr: 4.517 ± 0.769
4.329SerVal: 4.329 ± 1.028
0.188SerTrp: 0.188 ± 0.198
3.764SerTyr: 3.764 ± 0.943
0.0SerXaa: 0.0 ± 0.0
Thr
2.823ThrAla: 2.823 ± 0.674
0.753ThrCys: 0.753 ± 0.427
3.764ThrAsp: 3.764 ± 1.223
3.764ThrGlu: 3.764 ± 0.388
1.882ThrPhe: 1.882 ± 0.644
1.694ThrGly: 1.694 ± 0.611
0.565ThrHis: 0.565 ± 0.241
6.964ThrIle: 6.964 ± 0.634
2.635ThrLys: 2.635 ± 0.572
6.399ThrLeu: 6.399 ± 0.834
1.129ThrMet: 1.129 ± 0.438
4.705ThrAsn: 4.705 ± 0.763
1.694ThrPro: 1.694 ± 0.387
1.318ThrGln: 1.318 ± 0.524
2.07ThrArg: 2.07 ± 0.692
5.082ThrSer: 5.082 ± 0.94
2.823ThrThr: 2.823 ± 0.486
2.635ThrVal: 2.635 ± 0.581
0.565ThrTrp: 0.565 ± 0.447
3.764ThrTyr: 3.764 ± 1.604
0.0ThrXaa: 0.0 ± 0.0
Val
2.07ValAla: 2.07 ± 0.758
0.753ValCys: 0.753 ± 0.368
2.823ValAsp: 2.823 ± 0.54
3.764ValGlu: 3.764 ± 0.814
2.447ValPhe: 2.447 ± 0.572
0.941ValGly: 0.941 ± 0.218
0.941ValHis: 0.941 ± 0.249
4.517ValIle: 4.517 ± 0.732
4.705ValLys: 4.705 ± 0.884
4.705ValLeu: 4.705 ± 0.687
0.753ValMet: 0.753 ± 0.288
2.259ValAsn: 2.259 ± 0.403
1.882ValPro: 1.882 ± 0.523
0.941ValGln: 0.941 ± 0.569
2.07ValArg: 2.07 ± 0.283
3.011ValSer: 3.011 ± 0.594
3.011ValThr: 3.011 ± 0.41
1.129ValVal: 1.129 ± 0.679
0.0ValTrp: 0.0 ± 0.0
2.635ValTyr: 2.635 ± 0.725
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.188TrpCys: 0.188 ± 0.109
0.188TrpAsp: 0.188 ± 0.198
0.376TrpGlu: 0.376 ± 0.309
0.188TrpPhe: 0.188 ± 0.109
0.188TrpGly: 0.188 ± 0.198
0.0TrpHis: 0.0 ± 0.0
0.188TrpIle: 0.188 ± 0.191
0.753TrpLys: 0.753 ± 0.409
0.753TrpLeu: 0.753 ± 0.302
0.188TrpMet: 0.188 ± 0.201
0.565TrpAsn: 0.565 ± 0.263
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.376TrpArg: 0.376 ± 0.291
0.188TrpSer: 0.188 ± 0.109
0.188TrpThr: 0.188 ± 0.198
0.0TrpVal: 0.0 ± 0.0
0.188TrpTrp: 0.188 ± 0.191
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.941TyrAla: 0.941 ± 0.397
0.753TyrCys: 0.753 ± 0.322
3.576TyrAsp: 3.576 ± 0.398
2.447TyrGlu: 2.447 ± 0.477
1.506TyrPhe: 1.506 ± 0.329
2.635TyrGly: 2.635 ± 0.461
0.941TyrHis: 0.941 ± 0.36
6.588TyrIle: 6.588 ± 0.536
6.588TyrLys: 6.588 ± 1.586
3.764TyrLeu: 3.764 ± 0.681
2.447TyrMet: 2.447 ± 0.461
6.776TyrAsn: 6.776 ± 0.589
2.07TyrPro: 2.07 ± 0.481
0.941TyrGln: 0.941 ± 0.401
2.07TyrArg: 2.07 ± 0.368
5.647TyrSer: 5.647 ± 1.154
3.953TyrThr: 3.953 ± 0.312
1.694TyrVal: 1.694 ± 0.425
0.188TyrTrp: 0.188 ± 0.201
4.705TyrTyr: 4.705 ± 0.601
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (5314 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski