Amino acid dipepetide frequency for Wenzhou yanvirus-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.255AlaAla: 8.255 ± 0.284
0.55AlaCys: 0.55 ± 0.267
6.054AlaAsp: 6.054 ± 0.494
5.504AlaGlu: 5.504 ± 1.81
3.302AlaPhe: 3.302 ± 1.6
7.155AlaGly: 7.155 ± 1.753
1.651AlaHis: 1.651 ± 0.057
4.403AlaIle: 4.403 ± 0.42
2.752AlaLys: 2.752 ± 0.477
9.906AlaLeu: 9.906 ± 1.198
2.752AlaMet: 2.752 ± 0.477
0.55AlaAsn: 0.55 ± 0.59
6.604AlaPro: 6.604 ± 2.798
1.101AlaGln: 1.101 ± 0.324
6.604AlaArg: 6.604 ± 2.343
3.853AlaSer: 3.853 ± 0.153
7.155AlaThr: 7.155 ± 0.039
4.403AlaVal: 4.403 ± 0.437
2.752AlaTrp: 2.752 ± 1.333
2.752AlaTyr: 2.752 ± 0.477
0.0AlaXaa: 0.0 ± 0.0
Cys
2.201CysAla: 2.201 ± 1.067
0.0CysCys: 0.0 ± 0.0
1.651CysAsp: 1.651 ± 0.057
1.101CysGlu: 1.101 ± 0.533
0.0CysPhe: 0.0 ± 0.0
2.201CysGly: 2.201 ± 1.067
0.0CysHis: 0.0 ± 0.0
0.55CysIle: 0.55 ± 0.267
0.55CysLys: 0.55 ± 0.267
2.752CysLeu: 2.752 ± 0.38
0.55CysMet: 0.55 ± 0.25
0.55CysAsn: 0.55 ± 0.267
0.55CysPro: 0.55 ± 0.267
0.55CysGln: 0.55 ± 0.267
0.55CysArg: 0.55 ± 0.267
0.55CysSer: 0.55 ± 0.267
1.101CysThr: 1.101 ± 0.533
2.752CysVal: 2.752 ± 1.333
0.0CysTrp: 0.0 ± 0.0
0.55CysTyr: 0.55 ± 0.267
0.0CysXaa: 0.0 ± 0.0
Asp
4.403AspAla: 4.403 ± 1.277
2.752AspCys: 2.752 ± 1.333
3.853AspAsp: 3.853 ± 1.01
3.853AspGlu: 3.853 ± 0.704
1.651AspPhe: 1.651 ± 0.8
3.853AspGly: 3.853 ± 1.867
1.101AspHis: 1.101 ± 0.533
1.651AspIle: 1.651 ± 0.057
1.651AspLys: 1.651 ± 0.057
4.403AspLeu: 4.403 ± 0.42
1.101AspMet: 1.101 ± 0.324
1.101AspAsn: 1.101 ± 0.533
4.953AspPro: 4.953 ± 1.027
1.651AspGln: 1.651 ± 0.914
1.651AspArg: 1.651 ± 0.8
5.504AspSer: 5.504 ± 2.474
3.853AspThr: 3.853 ± 0.704
3.302AspVal: 3.302 ± 0.743
0.55AspTrp: 0.55 ± 0.267
2.752AspTyr: 2.752 ± 1.237
0.0AspXaa: 0.0 ± 0.0
Glu
5.504GluAla: 5.504 ± 0.953
0.55GluCys: 0.55 ± 0.267
3.853GluAsp: 3.853 ± 1.867
2.752GluGlu: 2.752 ± 1.333
2.752GluPhe: 2.752 ± 0.38
3.302GluGly: 3.302 ± 0.743
1.651GluHis: 1.651 ± 0.8
3.302GluIle: 3.302 ± 0.971
6.054GluLys: 6.054 ± 1.22
3.853GluLeu: 3.853 ± 1.01
1.101GluMet: 1.101 ± 0.533
1.651GluAsn: 1.651 ± 0.057
3.853GluPro: 3.853 ± 1.01
1.651GluGln: 1.651 ± 0.8
3.853GluArg: 3.853 ± 1.561
4.953GluSer: 4.953 ± 0.686
2.201GluThr: 2.201 ± 1.504
2.752GluVal: 2.752 ± 1.333
0.55GluTrp: 0.55 ± 0.267
2.201GluTyr: 2.201 ± 0.647
0.0GluXaa: 0.0 ± 0.0
Phe
2.752PheAla: 2.752 ± 0.477
0.55PheCys: 0.55 ± 0.267
0.55PheAsp: 0.55 ± 0.267
1.101PheGlu: 1.101 ± 0.533
1.101PhePhe: 1.101 ± 0.324
3.302PheGly: 3.302 ± 0.743
0.0PheHis: 0.0 ± 0.0
2.201PheIle: 2.201 ± 0.21
0.0PheLys: 0.0 ± 0.0
3.302PheLeu: 3.302 ± 0.114
1.101PheMet: 1.101 ± 0.324
1.101PheAsn: 1.101 ± 0.324
0.55PhePro: 0.55 ± 0.267
0.55PheGln: 0.55 ± 0.267
2.201PheArg: 2.201 ± 2.361
1.651PheSer: 1.651 ± 0.8
2.201PheThr: 2.201 ± 0.647
2.752PheVal: 2.752 ± 1.237
1.101PheTrp: 1.101 ± 0.533
3.853PheTyr: 3.853 ± 0.153
0.0PheXaa: 0.0 ± 0.0
Gly
7.155GlyAla: 7.155 ± 0.039
2.201GlyCys: 2.201 ± 1.067
3.302GlyAsp: 3.302 ± 0.743
2.752GlyGlu: 2.752 ± 0.477
3.302GlyPhe: 3.302 ± 0.114
7.155GlyGly: 7.155 ± 0.896
2.201GlyHis: 2.201 ± 0.647
1.651GlyIle: 1.651 ± 0.8
4.403GlyLys: 4.403 ± 0.42
8.806GlyLeu: 8.806 ± 0.839
2.752GlyMet: 2.752 ± 1.333
2.201GlyAsn: 2.201 ± 0.647
6.054GlyPro: 6.054 ± 2.077
1.101GlyGln: 1.101 ± 0.533
7.155GlyArg: 7.155 ± 0.896
4.403GlySer: 4.403 ± 2.151
2.201GlyThr: 2.201 ± 1.504
4.953GlyVal: 4.953 ± 0.686
1.101GlyTrp: 1.101 ± 0.533
1.101GlyTyr: 1.101 ± 0.533
0.0GlyXaa: 0.0 ± 0.0
His
2.201HisAla: 2.201 ± 0.21
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.651HisGlu: 1.651 ± 0.8
0.55HisPhe: 0.55 ± 0.267
1.651HisGly: 1.651 ± 0.057
0.55HisHis: 0.55 ± 0.267
2.201HisIle: 2.201 ± 1.067
1.651HisLys: 1.651 ± 0.8
2.752HisLeu: 2.752 ± 0.477
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.201HisPro: 2.201 ± 0.21
1.101HisGln: 1.101 ± 0.324
2.201HisArg: 2.201 ± 1.067
3.302HisSer: 3.302 ± 0.743
1.101HisThr: 1.101 ± 1.18
0.55HisVal: 0.55 ± 0.267
1.651HisTrp: 1.651 ± 0.057
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.403IleAla: 4.403 ± 0.42
2.752IleCys: 2.752 ± 0.38
3.302IleAsp: 3.302 ± 0.114
2.201IleGlu: 2.201 ± 0.647
1.101IlePhe: 1.101 ± 1.18
2.752IleGly: 2.752 ± 0.477
0.0IleHis: 0.0 ± 0.0
2.752IleIle: 2.752 ± 0.38
3.853IleLys: 3.853 ± 1.01
3.853IleLeu: 3.853 ± 0.704
1.651IleMet: 1.651 ± 0.8
2.752IleAsn: 2.752 ± 0.477
3.302IlePro: 3.302 ± 0.971
2.752IleGln: 2.752 ± 0.477
0.55IleArg: 0.55 ± 0.267
2.201IleSer: 2.201 ± 0.647
1.651IleThr: 1.651 ± 0.8
2.752IleVal: 2.752 ± 0.38
0.0IleTrp: 0.0 ± 0.0
0.55IleTyr: 0.55 ± 0.59
0.0IleXaa: 0.0 ± 0.0
Lys
3.853LysAla: 3.853 ± 0.153
0.55LysCys: 0.55 ± 0.267
2.752LysAsp: 2.752 ± 0.477
4.953LysGlu: 4.953 ± 1.543
2.201LysPhe: 2.201 ± 0.21
7.705LysGly: 7.705 ± 0.551
1.651LysHis: 1.651 ± 0.8
0.55LysIle: 0.55 ± 0.267
3.853LysLys: 3.853 ± 0.153
3.853LysLeu: 3.853 ± 1.867
2.752LysMet: 2.752 ± 0.713
0.55LysAsn: 0.55 ± 0.267
3.853LysPro: 3.853 ± 1.01
2.752LysGln: 2.752 ± 2.094
4.953LysArg: 4.953 ± 0.686
1.651LysSer: 1.651 ± 0.057
4.953LysThr: 4.953 ± 1.884
2.201LysVal: 2.201 ± 0.21
1.651LysTrp: 1.651 ± 0.8
2.201LysTyr: 2.201 ± 1.067
0.0LysXaa: 0.0 ± 0.0
Leu
7.155LeuAla: 7.155 ± 0.817
0.55LeuCys: 0.55 ± 0.267
8.806LeuAsp: 8.806 ± 2.588
4.403LeuGlu: 4.403 ± 1.277
3.302LeuPhe: 3.302 ± 0.114
4.403LeuGly: 4.403 ± 0.437
1.651LeuHis: 1.651 ± 0.8
2.752LeuIle: 2.752 ± 0.38
5.504LeuLys: 5.504 ± 0.096
5.504LeuLeu: 5.504 ± 1.618
0.55LeuMet: 0.55 ± 0.267
3.853LeuAsn: 3.853 ± 0.704
4.953LeuPro: 4.953 ± 0.17
3.853LeuGln: 3.853 ± 0.704
6.604LeuArg: 6.604 ± 2.343
4.403LeuSer: 4.403 ± 0.437
8.255LeuThr: 8.255 ± 1.998
5.504LeuVal: 5.504 ± 0.761
1.101LeuTrp: 1.101 ± 0.533
2.201LeuTyr: 2.201 ± 0.21
0.0LeuXaa: 0.0 ± 0.0
Met
0.55MetAla: 0.55 ± 0.267
0.55MetCys: 0.55 ± 0.267
1.101MetAsp: 1.101 ± 0.533
1.101MetGlu: 1.101 ± 0.533
0.55MetPhe: 0.55 ± 0.267
1.651MetGly: 1.651 ± 0.8
1.101MetHis: 1.101 ± 0.533
1.101MetIle: 1.101 ± 0.324
2.201MetLys: 2.201 ± 0.647
2.201MetLeu: 2.201 ± 0.647
0.55MetMet: 0.55 ± 0.267
2.752MetAsn: 2.752 ± 1.237
1.101MetPro: 1.101 ± 0.324
1.101MetGln: 1.101 ± 0.533
2.201MetArg: 2.201 ± 0.21
1.651MetSer: 1.651 ± 0.057
1.101MetThr: 1.101 ± 0.324
1.651MetVal: 1.651 ± 0.8
0.0MetTrp: 0.0 ± 0.0
0.55MetTyr: 0.55 ± 0.59
0.0MetXaa: 0.0 ± 0.0
Asn
3.853AsnAla: 3.853 ± 1.561
0.55AsnCys: 0.55 ± 0.267
2.201AsnAsp: 2.201 ± 0.21
2.201AsnGlu: 2.201 ± 0.21
1.651AsnPhe: 1.651 ± 0.8
2.201AsnGly: 2.201 ± 0.21
0.55AsnHis: 0.55 ± 0.267
1.651AsnIle: 1.651 ± 0.057
1.101AsnLys: 1.101 ± 0.324
2.201AsnLeu: 2.201 ± 0.21
0.55AsnMet: 0.55 ± 0.59
0.55AsnAsn: 0.55 ± 0.59
3.853AsnPro: 3.853 ± 2.418
1.651AsnGln: 1.651 ± 0.8
0.55AsnArg: 0.55 ± 0.59
2.752AsnSer: 2.752 ± 0.38
1.651AsnThr: 1.651 ± 1.771
2.201AsnVal: 2.201 ± 1.504
0.55AsnTrp: 0.55 ± 0.267
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.302ProAla: 3.302 ± 0.114
1.651ProCys: 1.651 ± 0.8
5.504ProAsp: 5.504 ± 0.953
6.054ProGlu: 6.054 ± 0.494
0.55ProPhe: 0.55 ± 0.59
4.403ProGly: 4.403 ± 1.294
0.0ProHis: 0.0 ± 0.0
4.953ProIle: 4.953 ± 1.027
8.806ProLys: 8.806 ± 3.41
1.651ProLeu: 1.651 ± 0.914
0.55ProMet: 0.55 ± 0.267
3.302ProAsn: 3.302 ± 0.114
8.806ProPro: 8.806 ± 3.41
2.201ProGln: 2.201 ± 0.21
2.201ProArg: 2.201 ± 0.21
4.953ProSer: 4.953 ± 1.027
3.853ProThr: 3.853 ± 1.561
5.504ProVal: 5.504 ± 1.618
1.651ProTrp: 1.651 ± 0.057
2.752ProTyr: 2.752 ± 0.477
0.0ProXaa: 0.0 ± 0.0
Gln
2.201GlnAla: 2.201 ± 0.21
0.55GlnCys: 0.55 ± 0.267
0.0GlnAsp: 0.0 ± 0.0
2.752GlnGlu: 2.752 ± 0.477
0.55GlnPhe: 0.55 ± 0.267
1.101GlnGly: 1.101 ± 0.533
0.0GlnHis: 0.0 ± 0.0
1.101GlnIle: 1.101 ± 0.533
3.302GlnLys: 3.302 ± 0.114
1.651GlnLeu: 1.651 ± 1.771
0.55GlnMet: 0.55 ± 0.267
2.201GlnAsn: 2.201 ± 0.647
2.201GlnPro: 2.201 ± 0.21
1.651GlnGln: 1.651 ± 0.8
1.101GlnArg: 1.101 ± 0.324
2.201GlnSer: 2.201 ± 1.504
2.752GlnThr: 2.752 ± 1.237
1.651GlnVal: 1.651 ± 0.8
1.101GlnTrp: 1.101 ± 0.324
0.55GlnTyr: 0.55 ± 0.267
0.0GlnXaa: 0.0 ± 0.0
Arg
7.705ArgAla: 7.705 ± 1.163
0.55ArgCys: 0.55 ± 0.59
3.853ArgAsp: 3.853 ± 0.153
3.853ArgGlu: 3.853 ± 1.01
3.302ArgPhe: 3.302 ± 0.743
6.054ArgGly: 6.054 ± 2.077
2.201ArgHis: 2.201 ± 1.067
2.201ArgIle: 2.201 ± 0.647
2.201ArgLys: 2.201 ± 0.21
4.403ArgLeu: 4.403 ± 1.294
1.651ArgMet: 1.651 ± 0.057
0.55ArgAsn: 0.55 ± 0.59
3.302ArgPro: 3.302 ± 0.743
1.101ArgGln: 1.101 ± 0.533
4.403ArgArg: 4.403 ± 2.133
2.752ArgSer: 2.752 ± 0.477
6.054ArgThr: 6.054 ± 0.494
1.101ArgVal: 1.101 ± 1.18
0.0ArgTrp: 0.0 ± 0.0
3.853ArgTyr: 3.853 ± 1.561
0.0ArgXaa: 0.0 ± 0.0
Ser
4.403SerAla: 4.403 ± 0.42
2.201SerCys: 2.201 ± 1.067
3.302SerAsp: 3.302 ± 0.743
2.201SerGlu: 2.201 ± 0.21
0.55SerPhe: 0.55 ± 0.267
5.504SerGly: 5.504 ± 0.761
2.201SerHis: 2.201 ± 0.647
3.853SerIle: 3.853 ± 0.153
3.853SerLys: 3.853 ± 1.561
5.504SerLeu: 5.504 ± 0.761
2.201SerMet: 2.201 ± 0.647
1.651SerAsn: 1.651 ± 0.914
1.101SerPro: 1.101 ± 0.533
0.55SerGln: 0.55 ± 0.267
3.853SerArg: 3.853 ± 0.704
2.752SerSer: 2.752 ± 0.38
4.403SerThr: 4.403 ± 1.294
4.403SerVal: 4.403 ± 1.294
0.55SerTrp: 0.55 ± 0.267
4.403SerTyr: 4.403 ± 0.437
0.0SerXaa: 0.0 ± 0.0
Thr
4.953ThrAla: 4.953 ± 1.884
1.101ThrCys: 1.101 ± 0.533
2.752ThrAsp: 2.752 ± 1.237
1.651ThrGlu: 1.651 ± 0.914
3.302ThrPhe: 3.302 ± 1.827
4.953ThrGly: 4.953 ± 1.884
3.853ThrHis: 3.853 ± 0.153
4.403ThrIle: 4.403 ± 1.294
2.752ThrLys: 2.752 ± 2.951
9.356ThrLeu: 9.356 ± 1.465
1.101ThrMet: 1.101 ± 0.533
3.302ThrAsn: 3.302 ± 0.743
4.403ThrPro: 4.403 ± 0.42
2.752ThrGln: 2.752 ± 1.237
3.302ThrArg: 3.302 ± 1.827
2.201ThrSer: 2.201 ± 0.647
3.853ThrThr: 3.853 ± 0.153
4.953ThrVal: 4.953 ± 2.741
0.0ThrTrp: 0.0 ± 0.0
2.752ThrTyr: 2.752 ± 2.094
0.0ThrXaa: 0.0 ± 0.0
Val
8.255ValAla: 8.255 ± 0.573
0.0ValCys: 0.0 ± 0.0
0.55ValAsp: 0.55 ± 0.59
3.853ValGlu: 3.853 ± 1.01
1.101ValPhe: 1.101 ± 0.324
2.752ValGly: 2.752 ± 0.38
3.302ValHis: 3.302 ± 0.743
2.752ValIle: 2.752 ± 0.38
1.651ValLys: 1.651 ± 0.8
4.403ValLeu: 4.403 ± 1.294
1.651ValMet: 1.651 ± 0.914
2.201ValAsn: 2.201 ± 1.504
7.155ValPro: 7.155 ± 0.039
0.0ValGln: 0.0 ± 0.0
3.853ValArg: 3.853 ± 0.704
5.504ValSer: 5.504 ± 0.953
4.953ValThr: 4.953 ± 1.884
2.201ValVal: 2.201 ± 0.21
0.0ValTrp: 0.0 ± 0.0
1.651ValTyr: 1.651 ± 0.057
0.0ValXaa: 0.0 ± 0.0
Trp
2.752TrpAla: 2.752 ± 1.333
0.55TrpCys: 0.55 ± 0.267
0.0TrpAsp: 0.0 ± 0.0
2.201TrpGlu: 2.201 ± 0.647
0.55TrpPhe: 0.55 ± 0.59
1.651TrpGly: 1.651 ± 0.8
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.55TrpLys: 0.55 ± 0.267
2.752TrpLeu: 2.752 ± 1.333
0.55TrpMet: 0.55 ± 0.267
0.0TrpAsn: 0.0 ± 0.0
0.55TrpPro: 0.55 ± 0.267
0.0TrpGln: 0.0 ± 0.0
0.55TrpArg: 0.55 ± 0.267
0.0TrpSer: 0.0 ± 0.0
1.101TrpThr: 1.101 ± 0.533
0.55TrpVal: 0.55 ± 0.267
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.201TyrAla: 2.201 ± 1.067
0.55TyrCys: 0.55 ± 0.267
2.201TyrAsp: 2.201 ± 0.21
2.201TyrGlu: 2.201 ± 0.647
0.55TyrPhe: 0.55 ± 0.59
2.201TyrGly: 2.201 ± 0.21
1.651TyrHis: 1.651 ± 0.057
1.101TyrIle: 1.101 ± 0.533
3.302TyrLys: 3.302 ± 0.743
2.201TyrLeu: 2.201 ± 1.067
0.55TyrMet: 0.55 ± 0.59
1.651TyrAsn: 1.651 ± 0.914
3.302TyrPro: 3.302 ± 1.827
1.101TyrGln: 1.101 ± 1.18
2.752TyrArg: 2.752 ± 0.477
2.201TyrSer: 2.201 ± 0.21
3.302TyrThr: 3.302 ± 3.541
1.651TyrVal: 1.651 ± 0.8
0.0TyrTrp: 0.0 ± 0.0
2.201TyrTyr: 2.201 ± 0.21
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1818 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski