Amino acid dipepetide frequency for Turnip rosette virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.967AlaAla: 6.967 ± 1.586
1.608AlaCys: 1.608 ± 0.936
5.359AlaAsp: 5.359 ± 1.377
2.144AlaGlu: 2.144 ± 1.315
2.68AlaPhe: 2.68 ± 0.824
4.823AlaGly: 4.823 ± 0.911
1.608AlaHis: 1.608 ± 0.505
3.215AlaIle: 3.215 ± 1.3
2.68AlaLys: 2.68 ± 0.617
5.895AlaLeu: 5.895 ± 0.673
1.072AlaMet: 1.072 ± 0.658
1.608AlaAsn: 1.608 ± 0.505
2.68AlaPro: 2.68 ± 0.564
0.0AlaGln: 0.0 ± 0.0
5.359AlaArg: 5.359 ± 1.43
4.823AlaSer: 4.823 ± 0.901
2.68AlaThr: 2.68 ± 1.143
3.215AlaVal: 3.215 ± 1.3
0.536AlaTrp: 0.536 ± 0.329
1.072AlaTyr: 1.072 ± 0.977
0.0AlaXaa: 0.0 ± 0.0
Cys
2.68CysAla: 2.68 ± 0.921
0.0CysCys: 0.0 ± 0.0
1.608CysAsp: 1.608 ± 2.04
1.072CysGlu: 1.072 ± 2.173
0.536CysPhe: 0.536 ± 0.329
1.608CysGly: 1.608 ± 2.323
0.0CysHis: 0.0 ± 0.0
1.608CysIle: 1.608 ± 0.505
0.536CysLys: 0.536 ± 0.329
1.072CysLeu: 1.072 ± 0.977
0.0CysMet: 0.0 ± 0.0
2.144CysAsn: 2.144 ± 0.744
1.608CysPro: 1.608 ± 1.166
1.072CysGln: 1.072 ± 0.372
0.0CysArg: 0.0 ± 0.0
1.072CysSer: 1.072 ± 0.372
0.536CysThr: 0.536 ± 0.329
0.536CysVal: 0.536 ± 0.676
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.608AspAla: 1.608 ± 2.027
1.608AspCys: 1.608 ± 2.04
2.144AspAsp: 2.144 ± 0.811
3.751AspGlu: 3.751 ± 1.175
4.823AspPhe: 4.823 ± 1.536
5.895AspGly: 5.895 ± 0.49
0.0AspHis: 0.0 ± 0.0
3.215AspIle: 3.215 ± 0.878
1.072AspLys: 1.072 ± 1.351
2.68AspLeu: 2.68 ± 0.564
0.536AspMet: 0.536 ± 0.907
1.608AspAsn: 1.608 ± 0.499
1.608AspPro: 1.608 ± 0.505
2.144AspGln: 2.144 ± 0.811
5.359AspArg: 5.359 ± 1.196
3.215AspSer: 3.215 ± 1.756
1.072AspThr: 1.072 ± 1.351
0.536AspVal: 0.536 ± 0.329
1.608AspTrp: 1.608 ± 0.971
2.144AspTyr: 2.144 ± 0.766
0.0AspXaa: 0.0 ± 0.0
Glu
5.359GluAla: 5.359 ± 1.973
0.536GluCys: 0.536 ± 1.087
5.359GluAsp: 5.359 ± 1.5
5.895GluGlu: 5.895 ± 1.206
4.823GluPhe: 4.823 ± 1.586
3.215GluGly: 3.215 ± 0.799
0.0GluHis: 0.0 ± 0.0
7.503GluIle: 7.503 ± 0.113
2.144GluLys: 2.144 ± 0.454
8.574GluLeu: 8.574 ± 3.318
0.536GluMet: 0.536 ± 0.329
1.072GluAsn: 1.072 ± 0.977
3.751GluPro: 3.751 ± 1.256
1.072GluGln: 1.072 ± 0.658
5.895GluArg: 5.895 ± 0.436
4.823GluSer: 4.823 ± 1.275
4.823GluThr: 4.823 ± 4.012
5.359GluVal: 5.359 ± 1.52
1.072GluTrp: 1.072 ± 0.658
2.68GluTyr: 2.68 ± 0.809
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.072PheCys: 1.072 ± 0.637
3.215PheAsp: 3.215 ± 1.01
3.751PheGlu: 3.751 ± 0.802
0.0PhePhe: 0.0 ± 0.0
1.608PheGly: 1.608 ± 0.756
1.608PheHis: 1.608 ± 0.505
0.0PheIle: 0.0 ± 0.0
2.144PheLys: 2.144 ± 1.09
1.608PheLeu: 1.608 ± 0.756
0.536PheMet: 0.536 ± 0.329
1.072PheAsn: 1.072 ± 0.977
1.608PhePro: 1.608 ± 0.756
0.536PheGln: 0.536 ± 0.329
1.608PheArg: 1.608 ± 0.505
3.215PheSer: 3.215 ± 0.932
1.608PheThr: 1.608 ± 0.936
5.359PheVal: 5.359 ± 1.5
0.0PheTrp: 0.0 ± 0.0
1.072PheTyr: 1.072 ± 0.372
0.0PheXaa: 0.0 ± 0.0
Gly
3.751GlyAla: 3.751 ± 0.816
0.536GlyCys: 0.536 ± 1.087
3.215GlyAsp: 3.215 ± 0.533
4.287GlyGlu: 4.287 ± 1.483
1.608GlyPhe: 1.608 ± 0.756
2.144GlyGly: 2.144 ± 0.754
1.072GlyHis: 1.072 ± 0.658
6.431GlyIle: 6.431 ± 2.581
6.431GlyLys: 6.431 ± 2.433
4.823GlyLeu: 4.823 ± 0.911
1.608GlyMet: 1.608 ± 0.505
5.359GlyAsn: 5.359 ± 1.377
1.608GlyPro: 1.608 ± 0.936
0.0GlyGln: 0.0 ± 0.0
5.895GlyArg: 5.895 ± 1.573
6.431GlySer: 6.431 ± 1.353
7.503GlyThr: 7.503 ± 1.792
4.823GlyVal: 4.823 ± 0.911
1.608GlyTrp: 1.608 ± 0.505
2.68GlyTyr: 2.68 ± 1.112
0.0GlyXaa: 0.0 ± 0.0
His
1.072HisAla: 1.072 ± 0.977
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.072HisGlu: 1.072 ± 0.372
0.536HisPhe: 0.536 ± 0.676
1.072HisGly: 1.072 ± 0.372
0.0HisHis: 0.0 ± 0.0
0.536HisIle: 0.536 ± 0.329
2.68HisLys: 2.68 ± 0.824
3.215HisLeu: 3.215 ± 1.01
0.0HisMet: 0.0 ± 0.0
0.536HisAsn: 0.536 ± 0.329
1.072HisPro: 1.072 ± 0.658
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
3.215HisSer: 3.215 ± 0.799
0.0HisThr: 0.0 ± 0.0
2.68HisVal: 2.68 ± 0.824
0.536HisTrp: 0.536 ± 0.329
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.68IleAla: 2.68 ± 0.617
1.608IleCys: 1.608 ± 1.166
1.608IleAsp: 1.608 ± 0.499
3.215IleGlu: 3.215 ± 1.872
1.608IlePhe: 1.608 ± 0.505
3.751IleGly: 3.751 ± 1.256
2.144IleHis: 2.144 ± 0.744
2.68IleIle: 2.68 ± 0.921
0.536IleLys: 0.536 ± 0.676
1.608IleLeu: 1.608 ± 0.756
0.0IleMet: 0.0 ± 0.0
0.536IleAsn: 0.536 ± 0.329
1.608IlePro: 1.608 ± 0.756
1.608IleGln: 1.608 ± 0.803
2.68IleArg: 2.68 ± 0.617
5.895IleSer: 5.895 ± 1.573
5.359IleThr: 5.359 ± 1.861
5.359IleVal: 5.359 ± 1.869
2.144IleTrp: 2.144 ± 0.811
2.68IleTyr: 2.68 ± 0.921
0.0IleXaa: 0.0 ± 0.0
Lys
3.215LysAla: 3.215 ± 1.01
0.536LysCys: 0.536 ± 0.329
2.144LysAsp: 2.144 ± 0.454
6.967LysGlu: 6.967 ± 1.508
1.072LysPhe: 1.072 ± 1.351
6.431LysGly: 6.431 ± 1.129
0.536LysHis: 0.536 ± 0.329
1.072LysIle: 1.072 ± 0.372
5.895LysLys: 5.895 ± 1.338
6.967LysLeu: 6.967 ± 1.545
0.0LysMet: 0.0 ± 0.0
2.68LysAsn: 2.68 ± 1.035
1.608LysPro: 1.608 ± 0.756
2.144LysGln: 2.144 ± 1.071
1.072LysArg: 1.072 ± 0.976
5.359LysSer: 5.359 ± 1.128
4.823LysThr: 4.823 ± 2.137
2.144LysVal: 2.144 ± 0.744
1.608LysTrp: 1.608 ± 0.499
1.608LysTyr: 1.608 ± 1.166
0.0LysXaa: 0.0 ± 0.0
Leu
4.823LeuAla: 4.823 ± 1.032
0.536LeuCys: 0.536 ± 1.087
3.215LeuAsp: 3.215 ± 1.379
6.431LeuGlu: 6.431 ± 1.962
3.215LeuPhe: 3.215 ± 4.08
8.039LeuGly: 8.039 ± 1.893
1.072LeuHis: 1.072 ± 0.372
5.359LeuIle: 5.359 ± 1.112
2.144LeuLys: 2.144 ± 0.454
8.039LeuLeu: 8.039 ± 1.885
1.072LeuMet: 1.072 ± 0.658
5.359LeuAsn: 5.359 ± 1.65
3.751LeuPro: 3.751 ± 0.683
3.215LeuGln: 3.215 ± 0.998
4.823LeuArg: 4.823 ± 1.536
9.646LeuSer: 9.646 ± 2.563
5.895LeuThr: 5.895 ± 1.474
7.503LeuVal: 7.503 ± 2.892
0.536LeuTrp: 0.536 ± 0.676
3.215LeuTyr: 3.215 ± 1.042
0.0LeuXaa: 0.0 ± 0.0
Met
0.536MetAla: 0.536 ± 0.329
0.0MetCys: 0.0 ± 0.0
1.072MetAsp: 1.072 ± 0.637
1.072MetGlu: 1.072 ± 0.712
1.072MetPhe: 1.072 ± 0.372
3.751MetGly: 3.751 ± 1.256
1.072MetHis: 1.072 ± 0.372
0.0MetIle: 0.0 ± 0.0
1.072MetLys: 1.072 ± 0.658
1.072MetLeu: 1.072 ± 0.372
0.0MetMet: 0.0 ± 0.0
0.536MetAsn: 0.536 ± 0.329
0.536MetPro: 0.536 ± 0.676
0.536MetGln: 0.536 ± 0.676
0.0MetArg: 0.0 ± 0.0
1.608MetSer: 1.608 ± 0.936
0.0MetThr: 0.0 ± 0.0
1.072MetVal: 1.072 ± 0.372
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.144AsnAla: 2.144 ± 0.766
1.072AsnCys: 1.072 ± 0.372
1.072AsnAsp: 1.072 ± 0.372
2.144AsnGlu: 2.144 ± 1.09
2.144AsnPhe: 2.144 ± 0.766
3.751AsnGly: 3.751 ± 1.721
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
3.751AsnLys: 3.751 ± 1.182
1.072AsnLeu: 1.072 ± 0.637
0.0AsnMet: 0.0 ± 0.292
0.536AsnAsn: 0.536 ± 0.676
0.536AsnPro: 0.536 ± 0.329
1.072AsnGln: 1.072 ± 0.712
3.215AsnArg: 3.215 ± 1.01
3.751AsnSer: 3.751 ± 0.896
3.215AsnThr: 3.215 ± 0.998
4.287AsnVal: 4.287 ± 0.998
1.072AsnTrp: 1.072 ± 0.372
1.072AsnTyr: 1.072 ± 0.658
0.0AsnXaa: 0.0 ± 0.0
Pro
3.215ProAla: 3.215 ± 0.533
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
5.895ProGlu: 5.895 ± 1.018
0.0ProPhe: 0.0 ± 0.0
3.751ProGly: 3.751 ± 0.593
1.072ProHis: 1.072 ± 0.977
2.68ProIle: 2.68 ± 1.035
3.751ProLys: 3.751 ± 1.404
5.895ProLeu: 5.895 ± 1.213
0.0ProMet: 0.0 ± 0.0
1.608ProAsn: 1.608 ± 0.505
3.215ProPro: 3.215 ± 1.01
1.608ProGln: 1.608 ± 0.756
1.608ProArg: 1.608 ± 0.505
4.823ProSer: 4.823 ± 0.901
2.68ProThr: 2.68 ± 1.035
4.287ProVal: 4.287 ± 0.8
0.536ProTrp: 0.536 ± 0.329
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.072GlnAla: 1.072 ± 0.637
0.0GlnCys: 0.0 ± 0.0
1.608GlnAsp: 1.608 ± 0.505
3.751GlnGlu: 3.751 ± 1.256
0.536GlnPhe: 0.536 ± 0.329
3.215GlnGly: 3.215 ± 1.042
0.0GlnHis: 0.0 ± 0.0
0.536GlnIle: 0.536 ± 0.676
2.144GlnLys: 2.144 ± 1.129
2.144GlnLeu: 2.144 ± 0.454
1.072GlnMet: 1.072 ± 0.372
0.536GlnAsn: 0.536 ± 0.329
2.144GlnPro: 2.144 ± 0.744
0.536GlnGln: 0.536 ± 0.488
3.215GlnArg: 3.215 ± 0.953
0.536GlnSer: 0.536 ± 0.676
1.608GlnThr: 1.608 ± 1.464
3.215GlnVal: 3.215 ± 0.745
1.608GlnTrp: 1.608 ± 0.971
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.287ArgAla: 4.287 ± 1.234
0.0ArgCys: 0.0 ± 0.0
2.144ArgAsp: 2.144 ± 0.744
3.751ArgGlu: 3.751 ± 0.781
2.68ArgPhe: 2.68 ± 1.066
2.144ArgGly: 2.144 ± 0.454
1.608ArgHis: 1.608 ± 0.505
1.072ArgIle: 1.072 ± 0.658
8.039ArgLys: 8.039 ± 0.47
6.967ArgLeu: 6.967 ± 1.014
1.608ArgMet: 1.608 ± 0.499
2.68ArgAsn: 2.68 ± 0.824
2.144ArgPro: 2.144 ± 1.129
1.072ArgGln: 1.072 ± 0.372
3.751ArgArg: 3.751 ± 0.896
3.215ArgSer: 3.215 ± 1.01
1.072ArgThr: 1.072 ± 0.637
6.967ArgVal: 6.967 ± 0.629
1.072ArgTrp: 1.072 ± 0.658
1.072ArgTyr: 1.072 ± 0.372
0.0ArgXaa: 0.0 ± 0.0
Ser
2.68SerAla: 2.68 ± 1.153
1.072SerCys: 1.072 ± 0.372
4.287SerAsp: 4.287 ± 2.765
4.823SerGlu: 4.823 ± 4.031
0.536SerPhe: 0.536 ± 0.329
5.895SerGly: 5.895 ± 0.831
1.072SerHis: 1.072 ± 0.658
4.287SerIle: 4.287 ± 0.8
4.287SerLys: 4.287 ± 0.8
10.182SerLeu: 10.182 ± 1.79
1.072SerMet: 1.072 ± 0.372
2.68SerAsn: 2.68 ± 0.617
6.431SerPro: 6.431 ± 2.233
6.431SerGln: 6.431 ± 2.469
6.967SerArg: 6.967 ± 0.629
11.79SerSer: 11.79 ± 1.939
8.574SerThr: 8.574 ± 1.309
8.039SerVal: 8.039 ± 2.78
1.608SerTrp: 1.608 ± 0.499
1.072SerTyr: 1.072 ± 0.658
0.0SerXaa: 0.0 ± 0.0
Thr
4.287ThrAla: 4.287 ± 0.998
0.536ThrCys: 0.536 ± 1.087
0.536ThrAsp: 0.536 ± 0.329
8.574ThrGlu: 8.574 ± 2.082
1.072ThrPhe: 1.072 ± 0.637
1.072ThrGly: 1.072 ± 1.351
1.608ThrHis: 1.608 ± 0.505
3.215ThrIle: 3.215 ± 0.849
2.144ThrLys: 2.144 ± 1.128
5.895ThrLeu: 5.895 ± 1.213
1.608ThrMet: 1.608 ± 0.677
2.68ThrAsn: 2.68 ± 0.617
6.967ThrPro: 6.967 ± 2.133
2.68ThrGln: 2.68 ± 0.847
2.144ThrArg: 2.144 ± 0.454
8.039ThrSer: 8.039 ± 2.547
4.823ThrThr: 4.823 ± 2.411
11.79ThrVal: 11.79 ± 1.872
0.536ThrTrp: 0.536 ± 0.488
1.608ThrTyr: 1.608 ± 0.499
0.0ThrXaa: 0.0 ± 0.0
Val
5.359ValAla: 5.359 ± 1.421
5.359ValCys: 5.359 ± 0.898
4.823ValAsp: 4.823 ± 1.587
2.68ValGlu: 2.68 ± 1.066
2.68ValPhe: 2.68 ± 1.112
7.503ValGly: 7.503 ± 1.308
2.144ValHis: 2.144 ± 0.454
4.287ValIle: 4.287 ± 0.791
4.287ValLys: 4.287 ± 1.315
5.359ValLeu: 5.359 ± 1.128
2.144ValMet: 2.144 ± 1.022
1.608ValAsn: 1.608 ± 0.505
2.144ValPro: 2.144 ± 0.454
1.072ValGln: 1.072 ± 0.658
2.144ValArg: 2.144 ± 1.071
8.039ValSer: 8.039 ± 1.088
11.254ValThr: 11.254 ± 2.275
8.574ValVal: 8.574 ± 0.75
1.608ValTrp: 1.608 ± 0.499
4.823ValTyr: 4.823 ± 1.032
0.0ValXaa: 0.0 ± 0.0
Trp
2.144TrpAla: 2.144 ± 1.128
0.536TrpCys: 0.536 ± 0.329
1.072TrpAsp: 1.072 ± 0.658
1.608TrpGlu: 1.608 ± 0.971
0.0TrpPhe: 0.0 ± 0.0
1.072TrpGly: 1.072 ± 0.372
1.072TrpHis: 1.072 ± 0.372
0.536TrpIle: 0.536 ± 0.329
1.072TrpLys: 1.072 ± 0.658
0.536TrpLeu: 0.536 ± 0.329
1.072TrpMet: 1.072 ± 0.372
1.072TrpAsn: 1.072 ± 0.372
0.536TrpPro: 0.536 ± 0.329
0.536TrpGln: 0.536 ± 0.676
1.072TrpArg: 1.072 ± 0.372
1.608TrpSer: 1.608 ± 0.756
2.144TrpThr: 2.144 ± 0.744
0.536TrpVal: 0.536 ± 1.087
0.0TrpTrp: 0.0 ± 0.0
0.536TrpTyr: 0.536 ± 1.087
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.144TyrAla: 2.144 ± 1.636
1.072TyrCys: 1.072 ± 0.658
2.144TyrAsp: 2.144 ± 1.046
1.608TyrGlu: 1.608 ± 2.04
0.0TyrPhe: 0.0 ± 0.0
1.072TyrGly: 1.072 ± 0.372
0.536TyrHis: 0.536 ± 1.087
1.072TyrIle: 1.072 ± 0.372
1.072TyrLys: 1.072 ± 0.372
4.287TyrLeu: 4.287 ± 1.533
0.536TyrMet: 0.536 ± 0.676
0.536TyrAsn: 0.536 ± 1.087
1.072TyrPro: 1.072 ± 0.637
2.144TyrGln: 2.144 ± 0.766
0.536TyrArg: 0.536 ± 0.329
2.68TyrSer: 2.68 ± 0.921
2.144TyrThr: 2.144 ± 0.454
1.608TyrVal: 1.608 ± 0.756
1.072TyrTrp: 1.072 ± 0.372
0.536TyrTyr: 0.536 ± 0.676
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1867 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski