Human betaherpesvirus 6A

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus

Average proteome isoelectric point is 7.02

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 101 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|M9TG29|M9TG29_9BETA Tegument protein OS=Human betaherpesvirus 6A OX=32603 GN=U68 PE=3 SV=1
MM1 pKa = 7.47NSALNDD7 pKa = 3.36IKK9 pKa = 11.3DD10 pKa = 3.68DD11 pKa = 4.31FEE13 pKa = 5.15NCEE16 pKa = 4.24TKK18 pKa = 10.82DD19 pKa = 4.03DD20 pKa = 4.07LFKK23 pKa = 10.91IIDD26 pKa = 4.4KK27 pKa = 10.49IIKK30 pKa = 8.61NCDD33 pKa = 3.9FIVEE37 pKa = 4.36QVEE40 pKa = 4.37SLPRR44 pKa = 11.84RR45 pKa = 11.84VDD47 pKa = 3.15SAAILFDD54 pKa = 3.62NLAVEE59 pKa = 4.71IFNDD63 pKa = 3.75VIYY66 pKa = 10.21RR67 pKa = 11.84QNGVAAKK74 pKa = 9.65IRR76 pKa = 11.84QGNGQDD82 pKa = 2.99IDD84 pKa = 3.8TT85 pKa = 4.68

Molecular weight: 9.66 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|W8FUC4|W8FUC4_9BETA DR6 OS=Human betaherpesvirus 6A OX=32603 GN=DR6-R PE=4 SV=1
MM1 pKa = 7.3ARR3 pKa = 11.84VMARR7 pKa = 11.84VMARR11 pKa = 11.84VSTLATVRR19 pKa = 11.84VSTLARR25 pKa = 11.84ARR27 pKa = 11.84RR28 pKa = 11.84SVRR31 pKa = 11.84DD32 pKa = 3.45SFMVSVMVGVRR43 pKa = 11.84VRR45 pKa = 11.84VNVLVRR51 pKa = 11.84VNVLVRR57 pKa = 11.84ARR59 pKa = 11.84PRR61 pKa = 11.84VRR63 pKa = 11.84VRR65 pKa = 11.84ARR67 pKa = 11.84PRR69 pKa = 11.84VRR71 pKa = 11.84VRR73 pKa = 11.84VRR75 pKa = 11.84ARR77 pKa = 11.84PRR79 pKa = 11.84VRR81 pKa = 11.84VRR83 pKa = 11.84VRR85 pKa = 11.84ARR87 pKa = 11.84PRR89 pKa = 11.84VRR91 pKa = 11.84VRR93 pKa = 11.84VITPPFFSPPGGFNVIFKK111 pKa = 9.51TRR113 pKa = 11.84EE114 pKa = 3.24FCLPEE119 pKa = 3.9KK120 pKa = 10.67RR121 pKa = 11.84CWTKK125 pKa = 10.8KK126 pKa = 9.48CAGPGAVV133 pKa = 3.96

Molecular weight: 15.28 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

101

0

101

41757

70

2077

413.4

47.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.01 ± 0.135

2.567 ± 0.135

5.13 ± 0.173

5.621 ± 0.156

5.446 ± 0.175

4.2 ± 0.225

2.507 ± 0.095

6.729 ± 0.235

6.411 ± 0.262

10.006 ± 0.274

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.495 ± 0.119

5.666 ± 0.246

4.301 ± 0.182

3.628 ± 0.14

5.111 ± 0.276

8.197 ± 0.374

6.353 ± 0.237

6.174 ± 0.249

0.884 ± 0.074

3.563 ± 0.108
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski