Amino acid dipepetide frequency for Habropoda laboriosa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.934AlaAla: 4.934 ± 0.065	1.183AlaCys: 1.183 ± 0.03	2.721AlaAsp: 2.721 ± 0.027	3.875AlaGlu: 3.875 ± 0.041	2.108AlaPhe: 2.108 ± 0.022	3.326AlaGly: 3.326 ± 0.038	1.301AlaHis: 1.301 ± 0.018	3.389AlaIle: 3.389 ± 0.032	3.583AlaLys: 3.583 ± 0.049	5.539AlaLeu: 5.539 ± 0.045	1.406AlaMet: 1.406 ± 0.017	2.661AlaAsn: 2.661 ± 0.025	2.634AlaPro: 2.634 ± 0.032	2.305AlaGln: 2.305 ± 0.026	3.361AlaArg: 3.361 ± 0.046	4.697AlaSer: 4.697 ± 0.039	3.845AlaThr: 3.845 ± 0.033	3.941AlaVal: 3.941 ± 0.037	0.62AlaTrp: 0.62 ± 0.011	1.607AlaTyr: 1.607 ± 0.02	0.003AlaXaa: 0.003 ± 0.001
Cys	1.094CysAla: 1.094 ± 0.019	0.502CysCys: 0.502 ± 0.012	1.115CysAsp: 1.115 ± 0.022	1.179CysGlu: 1.179 ± 0.024	0.75CysPhe: 0.75 ± 0.012	1.363CysGly: 1.363 ± 0.049	0.519CysHis: 0.519 ± 0.013	1.222CysIle: 1.222 ± 0.031	1.236CysLys: 1.236 ± 0.022	1.856CysLeu: 1.856 ± 0.031	0.439CysMet: 0.439 ± 0.011	1.088CysAsn: 1.088 ± 0.025	1.103CysPro: 1.103 ± 0.044	0.814CysGln: 0.814 ± 0.03	1.174CysArg: 1.174 ± 0.044	1.646CysSer: 1.646 ± 0.046	1.219CysThr: 1.219 ± 0.033	1.267CysVal: 1.267 ± 0.041	0.239CysTrp: 0.239 ± 0.007	0.628CysTyr: 0.628 ± 0.012	0.001CysXaa: 0.001 ± 0.0
Asp	2.865AspAla: 2.865 ± 0.03	1.031AspCys: 1.031 ± 0.033	3.315AspAsp: 3.315 ± 0.034	4.075AspGlu: 4.075 ± 0.035	2.097AspPhe: 2.097 ± 0.047	2.951AspGly: 2.951 ± 0.035	1.1AspHis: 1.1 ± 0.015	3.435AspIle: 3.435 ± 0.032	3.214AspLys: 3.214 ± 0.039	4.641AspLeu: 4.641 ± 0.033	1.18AspMet: 1.18 ± 0.015	2.606AspAsn: 2.606 ± 0.027	2.447AspPro: 2.447 ± 0.057	1.709AspGln: 1.709 ± 0.021	2.708AspArg: 2.708 ± 0.032	4.217AspSer: 4.217 ± 0.038	3.053AspThr: 3.053 ± 0.033	3.509AspVal: 3.509 ± 0.032	0.61AspTrp: 0.61 ± 0.012	1.77AspTyr: 1.77 ± 0.021	0.001AspXaa: 0.001 ± 0.001
Glu	4.026GluAla: 4.026 ± 0.046	1.29GluCys: 1.29 ± 0.049	4.232GluAsp: 4.232 ± 0.039	7.174GluGlu: 7.174 ± 0.149	2.15GluPhe: 2.15 ± 0.021	3.256GluGly: 3.256 ± 0.066	1.523GluHis: 1.523 ± 0.018	4.182GluIle: 4.182 ± 0.041	5.691GluLys: 5.691 ± 0.128	5.825GluLeu: 5.825 ± 0.055	1.568GluMet: 1.568 ± 0.018	4.161GluAsn: 4.161 ± 0.038	2.486GluPro: 2.486 ± 0.03	2.89GluGln: 2.89 ± 0.048	4.064GluArg: 4.064 ± 0.041	4.804GluSer: 4.804 ± 0.043	4.043GluThr: 4.043 ± 0.045	3.885GluVal: 3.885 ± 0.055	0.676GluTrp: 0.676 ± 0.012	2.015GluTyr: 2.015 ± 0.019	0.002GluXaa: 0.002 ± 0.0
Phe	1.992PheAla: 1.992 ± 0.024	0.805PheCys: 0.805 ± 0.014	1.959PheAsp: 1.959 ± 0.021	2.198PheGlu: 2.198 ± 0.047	1.546PhePhe: 1.546 ± 0.022	2.189PheGly: 2.189 ± 0.05	0.999PheHis: 0.999 ± 0.014	1.99PheIle: 1.99 ± 0.022	2.085PheLys: 2.085 ± 0.023	3.652PheLeu: 3.652 ± 0.052	0.789PheMet: 0.789 ± 0.013	1.725PheAsn: 1.725 ± 0.02	1.647PhePro: 1.647 ± 0.02	1.439PheGln: 1.439 ± 0.018	1.844PheArg: 1.844 ± 0.02	2.87PheSer: 2.87 ± 0.026	2.115PheThr: 2.115 ± 0.024	2.361PheVal: 2.361 ± 0.024	0.418PheTrp: 0.418 ± 0.009	1.319PheTyr: 1.319 ± 0.018	0.001PheXaa: 0.001 ± 0.0
Gly	3.033GlyAla: 3.033 ± 0.03	1.065GlyCys: 1.065 ± 0.031	2.723GlyAsp: 2.723 ± 0.032	3.263GlyGlu: 3.263 ± 0.037	2.057GlyPhe: 2.057 ± 0.029	4.209GlyGly: 4.209 ± 0.073	1.399GlyHis: 1.399 ± 0.024	3.233GlyIle: 3.233 ± 0.034	3.589GlyLys: 3.589 ± 0.053	4.496GlyLeu: 4.496 ± 0.06	1.174GlyMet: 1.174 ± 0.015	2.83GlyAsn: 2.83 ± 0.032	2.413GlyPro: 2.413 ± 0.044	2.042GlyGln: 2.042 ± 0.026	3.18GlyArg: 3.18 ± 0.051	4.592GlySer: 4.592 ± 0.047	3.385GlyThr: 3.385 ± 0.039	3.293GlyVal: 3.293 ± 0.042	0.652GlyTrp: 0.652 ± 0.013	1.93GlyTyr: 1.93 ± 0.034	0.002GlyXaa: 0.002 ± 0.001
His	1.35HisAla: 1.35 ± 0.021	0.584HisCys: 0.584 ± 0.012	1.085HisAsp: 1.085 ± 0.016	1.417HisGlu: 1.417 ± 0.02	1.011HisPhe: 1.011 ± 0.015	1.418HisGly: 1.418 ± 0.021	1.058HisHis: 1.058 ± 0.028	1.383HisIle: 1.383 ± 0.017	1.353HisLys: 1.353 ± 0.017	2.383HisLeu: 2.383 ± 0.028	0.571HisMet: 0.571 ± 0.012	1.137HisAsn: 1.137 ± 0.017	1.395HisPro: 1.395 ± 0.017	1.128HisGln: 1.128 ± 0.018	1.518HisArg: 1.518 ± 0.018	1.968HisSer: 1.968 ± 0.024	1.419HisThr: 1.419 ± 0.018	1.541HisVal: 1.541 ± 0.017	0.298HisTrp: 0.298 ± 0.007	0.851HisTyr: 0.851 ± 0.012	0.001HisXaa: 0.001 ± 0.0
Ile	3.49IleAla: 3.49 ± 0.033	1.275IleCys: 1.275 ± 0.027	3.16IleAsp: 3.16 ± 0.051	3.901IleGlu: 3.901 ± 0.035	2.335IlePhe: 2.335 ± 0.052	2.963IleGly: 2.963 ± 0.027	1.408IleHis: 1.408 ± 0.019	3.303IleIle: 3.303 ± 0.033	3.569IleLys: 3.569 ± 0.037	5.53IleLeu: 5.53 ± 0.051	1.176IleMet: 1.176 ± 0.015	2.923IleAsn: 2.923 ± 0.032	2.959IlePro: 2.959 ± 0.028	2.348IleGln: 2.348 ± 0.026	2.914IleArg: 2.914 ± 0.027	4.549IleSer: 4.549 ± 0.036	3.372IleThr: 3.372 ± 0.032	3.655IleVal: 3.655 ± 0.034	0.612IleTrp: 0.612 ± 0.015	1.841IleTyr: 1.841 ± 0.042	0.003IleXaa: 0.003 ± 0.001
Lys	3.351LysAla: 3.351 ± 0.039	1.317LysCys: 1.317 ± 0.032	3.592LysAsp: 3.592 ± 0.047	5.347LysGlu: 5.347 ± 0.069	2.173LysPhe: 2.173 ± 0.025	2.849LysGly: 2.849 ± 0.036	1.639LysHis: 1.639 ± 0.021	3.988LysIle: 3.988 ± 0.058	5.506LysLys: 5.506 ± 0.065	5.906LysLeu: 5.906 ± 0.046	1.505LysMet: 1.505 ± 0.017	3.45LysAsn: 3.45 ± 0.037	2.924LysPro: 2.924 ± 0.048	2.803LysGln: 2.803 ± 0.029	4.146LysArg: 4.146 ± 0.119	4.833LysSer: 4.833 ± 0.051	3.585LysThr: 3.585 ± 0.036	3.758LysVal: 3.758 ± 0.042	0.692LysTrp: 0.692 ± 0.011	2.203LysTyr: 2.203 ± 0.023	0.002LysXaa: 0.002 ± 0.001
Leu	5.618LeuAla: 5.618 ± 0.048	1.864LeuCys: 1.864 ± 0.024	4.637LeuAsp: 4.637 ± 0.038	6.258LeuGlu: 6.258 ± 0.053	3.141LeuPhe: 3.141 ± 0.035	4.454LeuGly: 4.454 ± 0.035	2.457LeuHis: 2.457 ± 0.026	4.647LeuIle: 4.647 ± 0.059	6.141LeuLys: 6.141 ± 0.044	8.695LeuLeu: 8.695 ± 0.067	1.935LeuMet: 1.935 ± 0.021	4.482LeuAsn: 4.482 ± 0.049	4.748LeuPro: 4.748 ± 0.053	4.425LeuGln: 4.425 ± 0.038	5.256LeuArg: 5.256 ± 0.044	7.182LeuSer: 7.182 ± 0.048	5.154LeuThr: 5.154 ± 0.034	5.007LeuVal: 5.007 ± 0.042	0.97LeuTrp: 0.97 ± 0.015	2.802LeuTyr: 2.802 ± 0.027	0.003LeuXaa: 0.003 ± 0.001
Met	1.454MetAla: 1.454 ± 0.02	0.445MetCys: 0.445 ± 0.011	1.284MetAsp: 1.284 ± 0.015	1.704MetGlu: 1.704 ± 0.018	0.823MetPhe: 0.823 ± 0.014	1.089MetGly: 1.089 ± 0.016	0.535MetHis: 0.535 ± 0.01	1.203MetIle: 1.203 ± 0.017	1.565MetLys: 1.565 ± 0.019	1.962MetLeu: 1.962 ± 0.021	0.571MetMet: 0.571 ± 0.012	1.11MetAsn: 1.11 ± 0.015	0.995MetPro: 0.995 ± 0.015	1.032MetGln: 1.032 ± 0.015	1.107MetArg: 1.107 ± 0.016	1.717MetSer: 1.717 ± 0.019	1.206MetThr: 1.206 ± 0.015	1.257MetVal: 1.257 ± 0.015	0.242MetTrp: 0.242 ± 0.007	0.745MetTyr: 0.745 ± 0.014	0.001MetXaa: 0.001 ± 0.0
Asn	2.944AsnAla: 2.944 ± 0.043	0.998AsnCys: 0.998 ± 0.022	2.776AsnAsp: 2.776 ± 0.049	3.519AsnGlu: 3.519 ± 0.033	1.896AsnPhe: 1.896 ± 0.022	2.965AsnGly: 2.965 ± 0.036	1.165AsnHis: 1.165 ± 0.02	3.399AsnIle: 3.399 ± 0.035	3.204AsnLys: 3.204 ± 0.03	4.55AsnLeu: 4.55 ± 0.037	1.167AsnMet: 1.167 ± 0.017	3.223AsnAsn: 3.223 ± 0.039	2.247AsnPro: 2.247 ± 0.037	1.937AsnGln: 1.937 ± 0.024	2.493AsnArg: 2.493 ± 0.021	4.223AsnSer: 4.223 ± 0.038	3.053AsnThr: 3.053 ± 0.032	3.648AsnVal: 3.648 ± 0.031	0.52AsnTrp: 0.52 ± 0.009	1.688AsnTyr: 1.688 ± 0.021	0.001AsnXaa: 0.001 ± 0.0
Pro	2.967ProAla: 2.967 ± 0.042	0.911ProCys: 0.911 ± 0.058	2.452ProAsp: 2.452 ± 0.023	3.345ProGlu: 3.345 ± 0.057	1.62ProPhe: 1.62 ± 0.021	2.969ProGly: 2.969 ± 0.092	1.211ProHis: 1.211 ± 0.02	2.58ProIle: 2.58 ± 0.022	2.762ProLys: 2.762 ± 0.042	4.096ProLeu: 4.096 ± 0.027	0.982ProMet: 0.982 ± 0.017	2.303ProAsn: 2.303 ± 0.039	4.282ProPro: 4.282 ± 0.074	2.093ProGln: 2.093 ± 0.029	2.782ProArg: 2.782 ± 0.04	4.346ProSer: 4.346 ± 0.054	3.188ProThr: 3.188 ± 0.034	3.283ProVal: 3.283 ± 0.039	0.514ProTrp: 0.514 ± 0.011	1.554ProTyr: 1.554 ± 0.02	0.003ProXaa: 0.003 ± 0.001
Gln	2.41GlnAla: 2.41 ± 0.029	0.838GlnCys: 0.838 ± 0.029	1.929GlnAsp: 1.929 ± 0.017	2.99GlnGlu: 2.99 ± 0.032	1.368GlnPhe: 1.368 ± 0.016	1.944GlnGly: 1.944 ± 0.025	1.216GlnHis: 1.216 ± 0.016	2.287GlnIle: 2.287 ± 0.025	2.724GlnLys: 2.724 ± 0.03	3.873GlnLeu: 3.873 ± 0.031	0.962GlnMet: 0.962 ± 0.015	2.295GlnAsn: 2.295 ± 0.026	2.11GlnPro: 2.11 ± 0.039	3.461GlnGln: 3.461 ± 0.081	2.545GlnArg: 2.545 ± 0.027	3.085GlnSer: 3.085 ± 0.037	2.407GlnThr: 2.407 ± 0.026	2.354GlnVal: 2.354 ± 0.023	0.455GlnTrp: 0.455 ± 0.009	1.29GlnTyr: 1.29 ± 0.018	0.001GlnXaa: 0.001 ± 0.0
Arg	3.068ArgAla: 3.068 ± 0.029	1.167ArgCys: 1.167 ± 0.025	2.94ArgAsp: 2.94 ± 0.036	4.0ArgGlu: 4.0 ± 0.116	1.912ArgPhe: 1.912 ± 0.021	3.03ArgGly: 3.03 ± 0.038	1.533ArgHis: 1.533 ± 0.023	3.085ArgIle: 3.085 ± 0.03	4.203ArgLys: 4.203 ± 0.049	4.949ArgLeu: 4.949 ± 0.047	1.218ArgMet: 1.218 ± 0.018	2.973ArgAsn: 2.973 ± 0.025	2.579ArgPro: 2.579 ± 0.04	2.325ArgGln: 2.325 ± 0.031	4.571ArgArg: 4.571 ± 0.124	4.498ArgSer: 4.498 ± 0.056	3.044ArgThr: 3.044 ± 0.027	3.072ArgVal: 3.072 ± 0.025	0.643ArgTrp: 0.643 ± 0.011	1.802ArgTyr: 1.802 ± 0.019	0.002ArgXaa: 0.002 ± 0.0
Ser	4.344SerAla: 4.344 ± 0.033	1.562SerCys: 1.562 ± 0.046	4.113SerAsp: 4.113 ± 0.035	4.916SerGlu: 4.916 ± 0.05	2.761SerPhe: 2.761 ± 0.048	4.72SerGly: 4.72 ± 0.039	1.832SerHis: 1.832 ± 0.022	4.416SerIle: 4.416 ± 0.049	4.912SerLys: 4.912 ± 0.046	7.02SerLeu: 7.02 ± 0.047	1.754SerMet: 1.754 ± 0.022	4.359SerAsn: 4.359 ± 0.039	4.578SerPro: 4.578 ± 0.058	3.199SerGln: 3.199 ± 0.033	4.47SerArg: 4.47 ± 0.052	8.771SerSer: 8.771 ± 0.098	5.576SerThr: 5.576 ± 0.059	4.864SerVal: 4.864 ± 0.036	0.845SerTrp: 0.845 ± 0.014	2.276SerTyr: 2.276 ± 0.023	0.003SerXaa: 0.003 ± 0.001
Thr	3.777ThrAla: 3.777 ± 0.038	1.261ThrCys: 1.261 ± 0.031	2.992ThrAsp: 2.992 ± 0.024	4.035ThrGlu: 4.035 ± 0.072	2.196ThrPhe: 2.196 ± 0.022	3.382ThrGly: 3.382 ± 0.033	1.284ThrHis: 1.284 ± 0.016	3.576ThrIle: 3.576 ± 0.033	3.588ThrLys: 3.588 ± 0.037	5.396ThrLeu: 5.396 ± 0.036	1.336ThrMet: 1.336 ± 0.016	2.981ThrAsn: 2.981 ± 0.026	3.452ThrPro: 3.452 ± 0.04	2.207ThrGln: 2.207 ± 0.028	2.904ThrArg: 2.904 ± 0.025	5.291ThrSer: 5.291 ± 0.046	4.634ThrThr: 4.634 ± 0.15	4.091ThrVal: 4.091 ± 0.041	0.638ThrTrp: 0.638 ± 0.011	1.745ThrTyr: 1.745 ± 0.02	0.002ThrXaa: 0.002 ± 0.001
Val	4.036ValAla: 4.036 ± 0.039	1.368ValCys: 1.368 ± 0.034	3.247ValAsp: 3.247 ± 0.027	4.163ValGlu: 4.163 ± 0.058	2.186ValPhe: 2.186 ± 0.024	3.092ValGly: 3.092 ± 0.026	1.537ValHis: 1.537 ± 0.017	3.477ValIle: 3.477 ± 0.031	3.938ValLys: 3.938 ± 0.042	5.463ValLeu: 5.463 ± 0.044	1.323ValMet: 1.323 ± 0.017	3.019ValAsn: 3.019 ± 0.035	3.364ValPro: 3.364 ± 0.045	2.64ValGln: 2.64 ± 0.028	3.1ValArg: 3.1 ± 0.024	4.81ValSer: 4.81 ± 0.037	4.015ValThr: 4.015 ± 0.045	3.96ValVal: 3.96 ± 0.036	0.676ValTrp: 0.676 ± 0.012	1.89ValTyr: 1.89 ± 0.02	0.002ValXaa: 0.002 ± 0.001
Trp	0.558TrpAla: 0.558 ± 0.011	0.237TrpCys: 0.237 ± 0.006	0.574TrpAsp: 0.574 ± 0.013	0.637TrpGlu: 0.637 ± 0.011	0.441TrpPhe: 0.441 ± 0.009	0.551TrpGly: 0.551 ± 0.012	0.275TrpHis: 0.275 ± 0.007	0.687TrpIle: 0.687 ± 0.014	0.788TrpLys: 0.788 ± 0.015	1.071TrpLeu: 1.071 ± 0.017	0.274TrpMet: 0.274 ± 0.006	0.62TrpAsn: 0.62 ± 0.011	0.429TrpPro: 0.429 ± 0.009	0.453TrpGln: 0.453 ± 0.009	0.689TrpArg: 0.689 ± 0.011	0.833TrpSer: 0.833 ± 0.013	0.617TrpThr: 0.617 ± 0.011	0.585TrpVal: 0.585 ± 0.013	0.183TrpTrp: 0.183 ± 0.006	0.379TrpTyr: 0.379 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.726TyrAla: 1.726 ± 0.021	0.752TyrCys: 0.752 ± 0.013	1.687TyrAsp: 1.687 ± 0.019	1.948TyrGlu: 1.948 ± 0.023	1.367TyrPhe: 1.367 ± 0.016	1.839TyrGly: 1.839 ± 0.023	0.88TyrHis: 0.88 ± 0.014	1.796TyrIle: 1.796 ± 0.02	1.919TyrLys: 1.919 ± 0.021	2.966TyrLeu: 2.966 ± 0.047	0.715TyrMet: 0.715 ± 0.012	1.667TyrAsn: 1.667 ± 0.021	1.452TyrPro: 1.452 ± 0.028	1.296TyrGln: 1.296 ± 0.017	1.782TyrArg: 1.782 ± 0.019	2.356TyrSer: 2.356 ± 0.025	1.838TyrThr: 1.838 ± 0.022	1.975TyrVal: 1.975 ± 0.024	0.376TyrTrp: 0.376 ± 0.01	1.224TyrTyr: 1.224 ± 0.017	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.002XaaPhe: 0.002 ± 0.001	0.002XaaGly: 0.002 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.004XaaIle: 0.004 ± 0.001	0.001XaaLys: 0.001 ± 0.0	0.003XaaLeu: 0.003 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.002XaaAsn: 0.002 ± 0.001	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.001	0.003XaaArg: 0.003 ± 0.001	0.003XaaSer: 0.003 ± 0.001	0.002XaaThr: 0.002 ± 0.001	0.002XaaVal: 0.002 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.002XaaTyr: 0.002 ± 0.001	1.02XaaXaa: 1.02 ± 0.126

Statistics based on 12781 proteins (5864692 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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