Amino acid dipepetide frequency for Cacao swollen shoot virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.527AlaAla: 5.527 ± 4.119
0.0AlaCys: 0.0 ± 0.0
1.276AlaAsp: 1.276 ± 0.853
3.401AlaGlu: 3.401 ± 1.573
3.401AlaPhe: 3.401 ± 1.713
1.701AlaGly: 1.701 ± 2.172
1.276AlaHis: 1.276 ± 0.891
5.102AlaIle: 5.102 ± 2.925
3.401AlaLys: 3.401 ± 3.195
4.677AlaLeu: 4.677 ± 4.291
1.276AlaMet: 1.276 ± 0.642
1.276AlaAsn: 1.276 ± 0.891
0.85AlaPro: 0.85 ± 0.428
3.827AlaGln: 3.827 ± 2.447
3.827AlaArg: 3.827 ± 1.204
5.527AlaSer: 5.527 ± 1.678
3.401AlaThr: 3.401 ± 3.015
4.677AlaVal: 4.677 ± 3.136
0.425AlaTrp: 0.425 ± 0.214
4.252AlaTyr: 4.252 ± 0.892
0.0AlaXaa: 0.0 ± 0.0
Cys
0.85CysAla: 0.85 ± 0.428
0.425CysCys: 0.425 ± 0.214
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.85CysPhe: 0.85 ± 0.428
0.425CysGly: 0.425 ± 0.214
0.85CysHis: 0.85 ± 0.428
0.425CysIle: 0.425 ± 0.214
2.126CysLys: 2.126 ± 1.071
0.85CysLeu: 0.85 ± 0.963
0.85CysMet: 0.85 ± 0.428
0.85CysAsn: 0.85 ± 0.428
0.85CysPro: 0.85 ± 0.428
1.701CysGln: 1.701 ± 0.856
0.425CysArg: 0.425 ± 0.214
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.425CysVal: 0.425 ± 0.214
0.0CysTrp: 0.0 ± 0.0
1.276CysTyr: 1.276 ± 0.642
0.0CysXaa: 0.0 ± 0.0
Asp
2.126AspAla: 2.126 ± 0.859
0.85AspCys: 0.85 ± 0.428
1.701AspAsp: 1.701 ± 0.745
3.401AspGlu: 3.401 ± 1.713
0.425AspPhe: 0.425 ± 0.214
3.401AspGly: 3.401 ± 0.937
0.425AspHis: 0.425 ± 0.992
2.551AspIle: 2.551 ± 1.285
2.976AspLys: 2.976 ± 1.626
4.252AspLeu: 4.252 ± 1.064
0.85AspMet: 0.85 ± 0.428
1.701AspAsn: 1.701 ± 0.89
4.252AspPro: 4.252 ± 1.901
5.102AspGln: 5.102 ± 0.757
1.701AspArg: 1.701 ± 1.518
2.551AspSer: 2.551 ± 1.941
3.401AspThr: 3.401 ± 1.167
0.85AspVal: 0.85 ± 0.428
0.425AspTrp: 0.425 ± 0.214
2.976AspTyr: 2.976 ± 0.949
0.0AspXaa: 0.0 ± 0.0
Glu
3.827GluAla: 3.827 ± 2.558
0.85GluCys: 0.85 ± 0.428
5.527GluAsp: 5.527 ± 1.431
12.33GluGlu: 12.33 ± 3.259
2.126GluPhe: 2.126 ± 1.071
4.677GluGly: 4.677 ± 2.355
1.701GluHis: 1.701 ± 0.856
4.677GluIle: 4.677 ± 1.78
8.078GluLys: 8.078 ± 3.961
3.827GluLeu: 3.827 ± 0.811
2.126GluMet: 2.126 ± 1.079
3.827GluAsn: 3.827 ± 1.323
1.701GluPro: 1.701 ± 1.528
4.252GluGln: 4.252 ± 1.907
2.126GluArg: 2.126 ± 0.859
7.228GluSer: 7.228 ± 2.703
4.252GluThr: 4.252 ± 2.141
5.102GluVal: 5.102 ± 2.341
1.701GluTrp: 1.701 ± 0.851
2.551GluTyr: 2.551 ± 0.927
0.0GluXaa: 0.0 ± 0.0
Phe
2.551PheAla: 2.551 ± 1.285
0.85PheCys: 0.85 ± 0.428
2.126PheAsp: 2.126 ± 0.864
1.276PheGlu: 1.276 ± 0.642
0.425PhePhe: 0.425 ± 0.214
1.276PheGly: 1.276 ± 0.853
1.276PheHis: 1.276 ± 0.642
2.976PheIle: 2.976 ± 1.032
2.551PheLys: 2.551 ± 2.312
2.551PheLeu: 2.551 ± 1.285
1.276PheMet: 1.276 ± 0.642
1.701PheAsn: 1.701 ± 0.856
0.85PhePro: 0.85 ± 0.428
1.276PheGln: 1.276 ± 0.642
2.126PheArg: 2.126 ± 0.864
2.551PheSer: 2.551 ± 1.285
0.425PheThr: 0.425 ± 0.214
0.85PheVal: 0.85 ± 0.428
0.425PheTrp: 0.425 ± 0.214
1.701PheTyr: 1.701 ± 0.856
0.0PheXaa: 0.0 ± 0.0
Gly
1.701GlyAla: 1.701 ± 0.89
0.85GlyCys: 0.85 ± 0.428
2.126GlyAsp: 2.126 ± 1.071
4.677GlyGlu: 4.677 ± 1.146
2.551GlyPhe: 2.551 ± 1.705
2.551GlyGly: 2.551 ± 0.879
2.126GlyHis: 2.126 ± 0.772
3.827GlyIle: 3.827 ± 1.901
4.252GlyLys: 4.252 ± 2.283
5.102GlyLeu: 5.102 ± 1.008
2.126GlyMet: 2.126 ± 0.772
2.126GlyAsn: 2.126 ± 0.864
0.85GlyPro: 0.85 ± 0.428
2.126GlyGln: 2.126 ± 0.864
4.677GlyArg: 4.677 ± 1.525
2.976GlySer: 2.976 ± 1.499
4.252GlyThr: 4.252 ± 0.892
3.401GlyVal: 3.401 ± 2.156
0.85GlyTrp: 0.85 ± 0.428
1.276GlyTyr: 1.276 ± 0.642
0.0GlyXaa: 0.0 ± 0.0
His
1.276HisAla: 1.276 ± 0.97
0.85HisCys: 0.85 ± 0.428
0.425HisAsp: 0.425 ± 0.214
0.85HisGlu: 0.85 ± 0.428
1.276HisPhe: 1.276 ± 0.97
1.276HisGly: 1.276 ± 0.97
0.425HisHis: 0.425 ± 0.214
2.551HisIle: 2.551 ± 1.285
1.276HisLys: 1.276 ± 1.439
3.401HisLeu: 3.401 ± 1.49
0.0HisMet: 0.0 ± 0.0
1.276HisAsn: 1.276 ± 0.891
0.425HisPro: 0.425 ± 0.214
2.551HisGln: 2.551 ± 0.853
2.126HisArg: 2.126 ± 1.071
0.425HisSer: 0.425 ± 0.214
3.401HisThr: 3.401 ± 0.882
1.276HisVal: 1.276 ± 0.642
0.85HisTrp: 0.85 ± 0.428
0.85HisTyr: 0.85 ± 0.428
0.0HisXaa: 0.0 ± 0.0
Ile
3.401IleAla: 3.401 ± 0.836
1.701IleCys: 1.701 ± 0.786
2.976IleAsp: 2.976 ± 1.499
4.677IleGlu: 4.677 ± 1.808
2.126IlePhe: 2.126 ± 1.071
3.401IleGly: 3.401 ± 1.126
1.276IleHis: 1.276 ± 0.642
2.126IleIle: 2.126 ± 0.859
5.527IleLys: 5.527 ± 0.881
6.803IleLeu: 6.803 ± 1.09
0.85IleMet: 0.85 ± 0.866
2.126IleAsn: 2.126 ± 0.859
4.252IlePro: 4.252 ± 1.136
4.677IleGln: 4.677 ± 2.193
2.976IleArg: 2.976 ± 1.499
2.976IleSer: 2.976 ± 1.113
5.527IleThr: 5.527 ± 3.958
3.401IleVal: 3.401 ± 1.167
0.85IleTrp: 0.85 ± 0.428
1.701IleTyr: 1.701 ± 0.856
0.0IleXaa: 0.0 ± 0.0
Lys
4.252LysAla: 4.252 ± 3.576
0.85LysCys: 0.85 ± 0.428
4.252LysAsp: 4.252 ± 3.295
5.527LysGlu: 5.527 ± 2.328
0.85LysPhe: 0.85 ± 0.428
3.827LysGly: 3.827 ± 1.994
2.976LysHis: 2.976 ± 1.499
3.827LysIle: 3.827 ± 1.665
9.354LysLys: 9.354 ± 7.773
6.803LysLeu: 6.803 ± 4.113
2.551LysMet: 2.551 ± 1.557
2.551LysAsn: 2.551 ± 0.927
3.827LysPro: 3.827 ± 1.665
3.401LysGln: 3.401 ± 3.262
5.102LysArg: 5.102 ± 1.088
5.102LysSer: 5.102 ± 1.393
3.827LysThr: 3.827 ± 0.811
3.827LysVal: 3.827 ± 2.501
1.276LysTrp: 1.276 ± 0.779
0.85LysTyr: 0.85 ± 0.428
0.0LysXaa: 0.0 ± 0.0
Leu
7.653LeuAla: 7.653 ± 5.865
1.276LeuCys: 1.276 ± 0.642
5.102LeuAsp: 5.102 ± 1.671
8.503LeuGlu: 8.503 ± 4.119
2.551LeuPhe: 2.551 ± 0.822
5.102LeuGly: 5.102 ± 1.862
2.551LeuHis: 2.551 ± 2.7
2.976LeuIle: 2.976 ± 1.626
5.102LeuLys: 5.102 ± 2.761
6.803LeuLeu: 6.803 ± 3.632
0.85LeuMet: 0.85 ± 0.827
1.701LeuAsn: 1.701 ± 0.851
2.976LeuPro: 2.976 ± 0.949
5.527LeuGln: 5.527 ± 2.742
5.527LeuArg: 5.527 ± 1.678
5.527LeuSer: 5.527 ± 1.94
5.102LeuThr: 5.102 ± 1.855
6.378LeuVal: 6.378 ± 1.5
0.85LeuTrp: 0.85 ± 0.428
2.551LeuTyr: 2.551 ± 0.879
0.0LeuXaa: 0.0 ± 0.0
Met
1.701MetAla: 1.701 ± 0.856
0.425MetCys: 0.425 ± 0.214
0.425MetAsp: 0.425 ± 0.214
3.827MetGlu: 3.827 ± 1.681
0.425MetPhe: 0.425 ± 0.214
1.276MetGly: 1.276 ± 0.642
0.425MetHis: 0.425 ± 0.214
1.701MetIle: 1.701 ± 1.731
2.551MetLys: 2.551 ± 2.597
0.85MetLeu: 0.85 ± 0.428
2.551MetMet: 2.551 ± 0.853
1.276MetAsn: 1.276 ± 0.779
1.701MetPro: 1.701 ± 0.856
1.276MetGln: 1.276 ± 0.642
0.85MetArg: 0.85 ± 0.428
2.126MetSer: 2.126 ± 2.105
2.126MetThr: 2.126 ± 0.775
1.701MetVal: 1.701 ± 0.856
0.0MetTrp: 0.0 ± 0.0
0.425MetTyr: 0.425 ± 0.214
0.0MetXaa: 0.0 ± 0.0
Asn
0.85AsnAla: 0.85 ± 1.086
0.425AsnCys: 0.425 ± 0.214
0.85AsnAsp: 0.85 ± 0.428
1.701AsnGlu: 1.701 ± 0.856
0.425AsnPhe: 0.425 ± 0.214
2.126AsnGly: 2.126 ± 0.772
0.85AsnHis: 0.85 ± 0.428
1.701AsnIle: 1.701 ± 0.856
3.827AsnLys: 3.827 ± 1.927
5.102AsnLeu: 5.102 ± 3.564
1.701AsnMet: 1.701 ± 0.745
0.85AsnAsn: 0.85 ± 1.694
1.276AsnPro: 1.276 ± 0.779
2.551AsnGln: 2.551 ± 0.927
1.701AsnArg: 1.701 ± 0.851
1.701AsnSer: 1.701 ± 1.518
2.126AsnThr: 2.126 ± 0.864
2.126AsnVal: 2.126 ± 0.775
0.85AsnTrp: 0.85 ± 1.086
1.701AsnTyr: 1.701 ± 0.856
0.0AsnXaa: 0.0 ± 0.0
Pro
3.827ProAla: 3.827 ± 1.85
0.0ProCys: 0.0 ± 0.0
2.126ProAsp: 2.126 ± 1.071
2.976ProGlu: 2.976 ± 1.626
0.85ProPhe: 0.85 ± 0.428
0.85ProGly: 0.85 ± 0.428
0.85ProHis: 0.85 ± 0.428
2.126ProIle: 2.126 ± 1.071
2.976ProLys: 2.976 ± 0.912
3.827ProLeu: 3.827 ± 1.323
2.126ProMet: 2.126 ± 1.131
2.976ProAsn: 2.976 ± 0.949
5.102ProPro: 5.102 ± 1.746
2.976ProGln: 2.976 ± 0.975
1.701ProArg: 1.701 ± 0.856
2.976ProSer: 2.976 ± 1.499
3.827ProThr: 3.827 ± 1.736
3.401ProVal: 3.401 ± 0.97
0.425ProTrp: 0.425 ± 0.214
2.126ProTyr: 2.126 ± 2.129
0.0ProXaa: 0.0 ± 0.0
Gln
3.401GlnAla: 3.401 ± 2.154
0.425GlnCys: 0.425 ± 0.214
2.976GlnAsp: 2.976 ± 1.759
5.527GlnGlu: 5.527 ± 1.931
1.701GlnPhe: 1.701 ± 0.856
3.827GlnGly: 3.827 ± 1.85
3.401GlnHis: 3.401 ± 0.937
3.827GlnIle: 3.827 ± 0.811
3.827GlnLys: 3.827 ± 1.957
6.803GlnLeu: 6.803 ± 2.155
2.126GlnMet: 2.126 ± 1.066
2.976GlnAsn: 2.976 ± 2.12
3.827GlnPro: 3.827 ± 0.994
6.803GlnGln: 6.803 ± 2.067
3.401GlnArg: 3.401 ± 1.126
2.551GlnSer: 2.551 ± 0.853
3.401GlnThr: 3.401 ± 1.713
1.276GlnVal: 1.276 ± 0.642
2.126GlnTrp: 2.126 ± 0.864
0.85GlnTyr: 0.85 ± 0.428
0.0GlnXaa: 0.0 ± 0.0
Arg
3.401ArgAla: 3.401 ± 1.781
0.425ArgCys: 0.425 ± 0.214
4.252ArgAsp: 4.252 ± 2.816
3.401ArgGlu: 3.401 ± 1.167
1.701ArgPhe: 1.701 ± 0.856
2.551ArgGly: 2.551 ± 0.879
0.0ArgHis: 0.0 ± 0.0
4.677ArgIle: 4.677 ± 1.525
4.677ArgLys: 4.677 ± 2.006
6.803ArgLeu: 6.803 ± 1.731
1.276ArgMet: 1.276 ± 0.642
2.126ArgAsn: 2.126 ± 1.071
2.976ArgPro: 2.976 ± 1.499
1.701ArgGln: 1.701 ± 0.856
5.952ArgArg: 5.952 ± 0.757
4.252ArgSer: 4.252 ± 1.474
2.976ArgThr: 2.976 ± 1.499
3.827ArgVal: 3.827 ± 2.673
2.126ArgTrp: 2.126 ± 1.13
1.276ArgTyr: 1.276 ± 0.642
0.0ArgXaa: 0.0 ± 0.0
Ser
1.701SerAla: 1.701 ± 2.172
0.425SerCys: 0.425 ± 0.214
2.551SerAsp: 2.551 ± 0.879
5.527SerGlu: 5.527 ± 2.055
2.126SerPhe: 2.126 ± 1.071
4.252SerGly: 4.252 ± 2.283
1.701SerHis: 1.701 ± 0.851
4.677SerIle: 4.677 ± 1.891
3.827SerLys: 3.827 ± 1.702
5.102SerLeu: 5.102 ± 1.44
1.276SerMet: 1.276 ± 0.642
1.276SerAsn: 1.276 ± 0.642
2.551SerPro: 2.551 ± 1.206
5.102SerGln: 5.102 ± 0.807
6.803SerArg: 6.803 ± 2.653
3.401SerSer: 3.401 ± 0.882
4.677SerThr: 4.677 ± 1.921
2.551SerVal: 2.551 ± 1.285
0.0SerTrp: 0.0 ± 0.0
1.276SerTyr: 1.276 ± 0.97
0.0SerXaa: 0.0 ± 0.0
Thr
4.677ThrAla: 4.677 ± 0.898
1.276ThrCys: 1.276 ± 0.642
2.551ThrAsp: 2.551 ± 0.822
6.378ThrGlu: 6.378 ± 1.561
2.976ThrPhe: 2.976 ± 1.729
5.527ThrGly: 5.527 ± 1.124
2.976ThrHis: 2.976 ± 0.949
5.952ThrIle: 5.952 ± 0.757
2.976ThrLys: 2.976 ± 0.912
4.252ThrLeu: 4.252 ± 3.295
1.276ThrMet: 1.276 ± 0.642
0.85ThrAsn: 0.85 ± 0.977
3.827ThrPro: 3.827 ± 1.927
2.551ThrGln: 2.551 ± 0.853
3.401ThrArg: 3.401 ± 1.435
4.252ThrSer: 4.252 ± 1.064
6.803ThrThr: 6.803 ± 2.543
2.976ThrVal: 2.976 ± 0.918
0.85ThrTrp: 0.85 ± 0.428
1.276ThrTyr: 1.276 ± 0.779
0.0ThrXaa: 0.0 ± 0.0
Val
3.401ValAla: 3.401 ± 0.836
0.425ValCys: 0.425 ± 0.214
2.551ValAsp: 2.551 ± 1.027
4.252ValGlu: 4.252 ± 2.616
4.252ValPhe: 4.252 ± 1.494
3.401ValGly: 3.401 ± 0.836
0.85ValHis: 0.85 ± 0.428
3.827ValIle: 3.827 ± 1.85
2.551ValLys: 2.551 ± 0.822
2.126ValLeu: 2.126 ± 0.859
1.701ValMet: 1.701 ± 0.745
0.85ValAsn: 0.85 ± 0.977
3.827ValPro: 3.827 ± 1.736
4.252ValGln: 4.252 ± 1.722
2.126ValArg: 2.126 ± 0.864
1.701ValSer: 1.701 ± 0.745
5.102ValThr: 5.102 ± 2.617
2.551ValVal: 2.551 ± 1.285
0.85ValTrp: 0.85 ± 0.428
1.701ValTyr: 1.701 ± 0.856
0.0ValXaa: 0.0 ± 0.0
Trp
0.85TrpAla: 0.85 ± 1.086
0.0TrpCys: 0.0 ± 0.0
0.85TrpAsp: 0.85 ± 0.428
1.701TrpGlu: 1.701 ± 0.851
0.0TrpPhe: 0.0 ± 0.0
0.85TrpGly: 0.85 ± 0.428
0.425TrpHis: 0.425 ± 0.214
1.701TrpIle: 1.701 ± 0.856
0.425TrpLys: 0.425 ± 0.214
1.276TrpLeu: 1.276 ± 0.642
0.425TrpMet: 0.425 ± 0.214
0.425TrpAsn: 0.425 ± 0.214
1.276TrpPro: 1.276 ± 0.642
1.701TrpGln: 1.701 ± 0.856
0.85TrpArg: 0.85 ± 0.866
0.85TrpSer: 0.85 ± 0.866
0.85TrpThr: 0.85 ± 0.428
0.85TrpVal: 0.85 ± 0.977
0.425TrpTrp: 0.425 ± 0.214
0.425TrpTyr: 0.425 ± 1.099
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.126TyrAla: 2.126 ± 1.071
0.85TyrCys: 0.85 ± 0.428
1.276TyrAsp: 1.276 ± 0.97
2.551TyrGlu: 2.551 ± 0.927
0.0TyrPhe: 0.0 ± 0.0
2.126TyrGly: 2.126 ± 0.772
0.425TyrHis: 0.425 ± 0.214
2.126TyrIle: 2.126 ± 1.071
2.551TyrLys: 2.551 ± 1.251
3.401TyrLeu: 3.401 ± 1.033
0.0TyrMet: 0.0 ± 0.0
1.701TyrAsn: 1.701 ± 0.856
1.276TyrPro: 1.276 ± 0.97
1.701TyrGln: 1.701 ± 0.786
2.976TyrArg: 2.976 ± 0.949
2.126TyrSer: 2.126 ± 0.859
2.126TyrThr: 2.126 ± 1.071
0.85TyrVal: 0.85 ± 0.428
0.85TyrTrp: 0.85 ± 0.428
0.85TyrTyr: 0.85 ± 0.428
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2353 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski