Amino acid dipepetide frequency for Hubei narna-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.79AlaAla: 6.79 ± 5.235
1.235AlaCys: 1.235 ± 0.606
2.469AlaAsp: 2.469 ± 0.058
1.235AlaGlu: 1.235 ± 0.606
3.086AlaPhe: 3.086 ± 0.879
4.938AlaGly: 4.938 ± 4.961
0.617AlaHis: 0.617 ± 0.937
1.235AlaIle: 1.235 ± 0.606
1.852AlaLys: 1.852 ± 0.274
5.556AlaLeu: 5.556 ± 0.448
0.617AlaMet: 0.617 ± 0.332
2.469AlaAsn: 2.469 ± 2.481
3.704AlaPro: 3.704 ± 4.355
0.617AlaGln: 0.617 ± 0.937
1.852AlaArg: 1.852 ± 1.543
6.79AlaSer: 6.79 ± 0.158
3.086AlaThr: 3.086 ± 0.879
1.852AlaVal: 1.852 ± 2.812
0.617AlaTrp: 0.617 ± 0.937
4.938AlaTyr: 4.938 ± 0.116
0.0AlaXaa: 0.0 ± 0.0
Cys
1.235CysAla: 1.235 ± 0.664
0.0CysCys: 0.0 ± 0.0
0.617CysAsp: 0.617 ± 0.332
0.0CysGlu: 0.0 ± 0.0
1.852CysPhe: 1.852 ± 1.543
0.617CysGly: 0.617 ± 0.332
0.617CysHis: 0.617 ± 0.937
1.235CysIle: 1.235 ± 0.606
0.0CysLys: 0.0 ± 0.0
1.235CysLeu: 1.235 ± 0.606
0.0CysMet: 0.0 ± 0.0
0.617CysAsn: 0.617 ± 0.332
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.852AspAla: 1.852 ± 0.274
0.617AspCys: 0.617 ± 0.332
1.852AspAsp: 1.852 ± 0.995
1.235AspGlu: 1.235 ± 0.664
4.938AspPhe: 4.938 ± 1.385
3.704AspGly: 3.704 ± 0.548
1.235AspHis: 1.235 ± 0.664
3.086AspIle: 3.086 ± 1.659
0.617AspLys: 0.617 ± 0.332
8.025AspLeu: 8.025 ± 3.044
0.617AspMet: 0.617 ± 0.332
0.617AspAsn: 0.617 ± 0.332
3.704AspPro: 3.704 ± 1.817
1.852AspGln: 1.852 ± 0.995
3.704AspArg: 3.704 ± 0.722
3.086AspSer: 3.086 ± 1.659
3.086AspThr: 3.086 ± 0.39
4.938AspVal: 4.938 ± 1.153
1.235AspTrp: 1.235 ± 0.664
2.469AspTyr: 2.469 ± 1.211
0.0AspXaa: 0.0 ± 0.0
Glu
3.086GluAla: 3.086 ± 0.879
0.0GluCys: 0.0 ± 0.0
1.852GluAsp: 1.852 ± 0.995
4.938GluGlu: 4.938 ± 1.385
1.235GluPhe: 1.235 ± 0.664
0.0GluGly: 0.0 ± 0.0
1.852GluHis: 1.852 ± 0.274
4.321GluIle: 4.321 ± 2.323
2.469GluLys: 2.469 ± 1.327
6.173GluLeu: 6.173 ± 0.78
0.617GluMet: 0.617 ± 0.332
2.469GluAsn: 2.469 ± 0.058
3.086GluPro: 3.086 ± 0.39
1.852GluGln: 1.852 ± 0.995
2.469GluArg: 2.469 ± 1.211
2.469GluSer: 2.469 ± 0.058
0.0GluThr: 0.0 ± 0.0
4.938GluVal: 4.938 ± 0.116
0.617GluTrp: 0.617 ± 0.332
0.617GluTyr: 0.617 ± 0.332
0.0GluXaa: 0.0 ± 0.0
Phe
3.704PheAla: 3.704 ± 0.548
1.235PheCys: 1.235 ± 0.664
1.852PheAsp: 1.852 ± 0.274
1.852PheGlu: 1.852 ± 0.274
3.086PhePhe: 3.086 ± 1.659
1.852PheGly: 1.852 ± 0.995
0.617PheHis: 0.617 ± 0.332
2.469PheIle: 2.469 ± 0.058
1.852PheLys: 1.852 ± 0.995
6.79PheLeu: 6.79 ± 2.381
0.617PheMet: 0.617 ± 0.332
2.469PheAsn: 2.469 ± 1.327
5.556PhePro: 5.556 ± 0.448
1.852PheGln: 1.852 ± 0.274
1.852PheArg: 1.852 ± 0.995
3.704PheSer: 3.704 ± 0.722
3.086PheThr: 3.086 ± 0.39
4.321PheVal: 4.321 ± 0.216
1.235PheTrp: 1.235 ± 0.664
1.235PheTyr: 1.235 ± 0.664
0.0PheXaa: 0.0 ± 0.0
Gly
2.469GlyAla: 2.469 ± 1.211
0.617GlyCys: 0.617 ± 0.332
6.79GlyAsp: 6.79 ± 2.381
2.469GlyGlu: 2.469 ± 1.327
1.235GlyPhe: 1.235 ± 0.664
4.321GlyGly: 4.321 ± 0.216
1.235GlyHis: 1.235 ± 0.606
4.321GlyIle: 4.321 ± 2.754
3.086GlyLys: 3.086 ± 0.879
5.556GlyLeu: 5.556 ± 0.821
0.617GlyMet: 0.617 ± 0.937
1.852GlyAsn: 1.852 ± 2.812
2.469GlyPro: 2.469 ± 1.327
4.321GlyGln: 4.321 ± 1.485
3.086GlyArg: 3.086 ± 0.39
6.173GlySer: 6.173 ± 1.759
7.407GlyThr: 7.407 ± 3.634
4.321GlyVal: 4.321 ± 1.485
0.0GlyTrp: 0.0 ± 0.0
1.852GlyTyr: 1.852 ± 0.274
0.0GlyXaa: 0.0 ± 0.0
His
1.235HisAla: 1.235 ± 0.606
0.0HisCys: 0.0 ± 0.0
1.852HisAsp: 1.852 ± 0.995
1.235HisGlu: 1.235 ± 0.606
0.617HisPhe: 0.617 ± 0.332
1.235HisGly: 1.235 ± 0.664
0.617HisHis: 0.617 ± 0.332
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.469HisLeu: 2.469 ± 1.327
0.0HisMet: 0.0 ± 0.0
0.617HisAsn: 0.617 ± 0.937
1.235HisPro: 1.235 ± 0.664
1.852HisGln: 1.852 ± 0.274
0.0HisArg: 0.0 ± 0.0
3.086HisSer: 3.086 ± 0.39
1.235HisThr: 1.235 ± 0.664
0.617HisVal: 0.617 ± 0.332
0.617HisTrp: 0.617 ± 0.937
1.235HisTyr: 1.235 ± 0.664
0.0HisXaa: 0.0 ± 0.0
Ile
3.086IleAla: 3.086 ± 0.879
0.617IleCys: 0.617 ± 0.937
2.469IleAsp: 2.469 ± 0.058
1.852IleGlu: 1.852 ± 0.274
0.617IlePhe: 0.617 ± 0.332
4.321IleGly: 4.321 ± 4.024
1.852IleHis: 1.852 ± 0.995
1.235IleIle: 1.235 ± 1.875
3.704IleLys: 3.704 ± 0.722
6.173IleLeu: 6.173 ± 3.318
0.617IleMet: 0.617 ± 0.332
2.469IleAsn: 2.469 ± 0.058
4.938IlePro: 4.938 ± 2.654
0.617IleGln: 0.617 ± 0.332
2.469IleArg: 2.469 ± 1.327
3.704IleSer: 3.704 ± 1.991
4.321IleThr: 4.321 ± 1.485
3.086IleVal: 3.086 ± 3.418
1.852IleTrp: 1.852 ± 0.274
1.235IleTyr: 1.235 ± 0.606
0.0IleXaa: 0.0 ± 0.0
Lys
2.469LysAla: 2.469 ± 1.211
0.0LysCys: 0.0 ± 0.0
1.235LysAsp: 1.235 ± 0.606
1.852LysGlu: 1.852 ± 0.995
1.852LysPhe: 1.852 ± 0.995
4.938LysGly: 4.938 ± 2.654
0.617LysHis: 0.617 ± 0.332
2.469LysIle: 2.469 ± 1.211
1.235LysLys: 1.235 ± 0.606
1.852LysLeu: 1.852 ± 0.274
2.469LysMet: 2.469 ± 0.058
3.086LysAsn: 3.086 ± 3.418
2.469LysPro: 2.469 ± 2.481
1.852LysGln: 1.852 ± 0.995
1.235LysArg: 1.235 ± 0.664
1.852LysSer: 1.852 ± 0.995
1.235LysThr: 1.235 ± 0.606
4.321LysVal: 4.321 ± 1.053
0.0LysTrp: 0.0 ± 0.0
1.852LysTyr: 1.852 ± 0.995
0.0LysXaa: 0.0 ± 0.0
Leu
4.938LeuAla: 4.938 ± 2.423
1.235LeuCys: 1.235 ± 0.664
6.173LeuAsp: 6.173 ± 2.049
5.556LeuGlu: 5.556 ± 0.448
4.938LeuPhe: 4.938 ± 1.385
4.938LeuGly: 4.938 ± 1.385
0.617LeuHis: 0.617 ± 0.332
4.938LeuIle: 4.938 ± 1.385
2.469LeuLys: 2.469 ± 0.058
10.494LeuLeu: 10.494 ± 4.371
1.235LeuMet: 1.235 ± 0.856
7.407LeuAsn: 7.407 ± 1.095
9.877LeuPro: 9.877 ± 4.04
6.173LeuGln: 6.173 ± 2.049
5.556LeuArg: 5.556 ± 1.717
15.432LeuSer: 15.432 ± 4.487
4.321LeuThr: 4.321 ± 2.323
4.321LeuVal: 4.321 ± 0.216
1.235LeuTrp: 1.235 ± 0.664
3.704LeuTyr: 3.704 ± 1.991
0.0LeuXaa: 0.0 ± 0.0
Met
3.086MetAla: 3.086 ± 0.879
0.0MetCys: 0.0 ± 0.0
1.235MetAsp: 1.235 ± 0.606
1.852MetGlu: 1.852 ± 0.995
0.617MetPhe: 0.617 ± 0.332
3.086MetGly: 3.086 ± 0.39
0.0MetHis: 0.0 ± 0.0
1.852MetIle: 1.852 ± 1.543
1.235MetLys: 1.235 ± 0.664
0.617MetLeu: 0.617 ± 0.332
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.235MetPro: 1.235 ± 0.664
1.235MetGln: 1.235 ± 0.606
2.469MetArg: 2.469 ± 1.327
0.617MetSer: 0.617 ± 0.332
0.617MetThr: 0.617 ± 0.937
0.617MetVal: 0.617 ± 0.937
0.0MetTrp: 0.0 ± 0.0
1.235MetTyr: 1.235 ± 0.664
0.0MetXaa: 0.0 ± 0.0
Asn
0.617AsnAla: 0.617 ± 0.937
0.617AsnCys: 0.617 ± 0.937
0.617AsnAsp: 0.617 ± 0.937
3.086AsnGlu: 3.086 ± 2.149
1.235AsnPhe: 1.235 ± 0.606
4.321AsnGly: 4.321 ± 0.216
0.0AsnHis: 0.0 ± 0.0
1.852AsnIle: 1.852 ± 0.274
0.617AsnLys: 0.617 ± 0.937
6.79AsnLeu: 6.79 ± 5.235
0.0AsnMet: 0.0 ± 0.0
3.704AsnAsn: 3.704 ± 3.086
3.086AsnPro: 3.086 ± 0.39
1.235AsnGln: 1.235 ± 0.664
1.235AsnArg: 1.235 ± 0.606
4.938AsnSer: 4.938 ± 1.153
2.469AsnThr: 2.469 ± 0.058
3.704AsnVal: 3.704 ± 0.722
0.0AsnTrp: 0.0 ± 0.0
1.852AsnTyr: 1.852 ± 0.274
0.0AsnXaa: 0.0 ± 0.0
Pro
5.556ProAla: 5.556 ± 3.36
0.617ProCys: 0.617 ± 0.937
3.704ProAsp: 3.704 ± 1.991
2.469ProGlu: 2.469 ± 0.058
2.469ProPhe: 2.469 ± 1.327
2.469ProGly: 2.469 ± 0.058
2.469ProHis: 2.469 ± 0.058
3.086ProIle: 3.086 ± 0.39
1.852ProLys: 1.852 ± 0.274
9.259ProLeu: 9.259 ± 4.977
1.235ProMet: 1.235 ± 0.606
0.617ProAsn: 0.617 ± 0.332
5.556ProPro: 5.556 ± 0.448
2.469ProGln: 2.469 ± 1.327
4.938ProArg: 4.938 ± 2.423
8.025ProSer: 8.025 ± 0.506
4.938ProThr: 4.938 ± 2.423
4.938ProVal: 4.938 ± 2.654
0.0ProTrp: 0.0 ± 0.0
2.469ProTyr: 2.469 ± 0.058
0.0ProXaa: 0.0 ± 0.0
Gln
0.617GlnAla: 0.617 ± 0.937
0.0GlnCys: 0.0 ± 0.0
1.235GlnAsp: 1.235 ± 0.606
2.469GlnGlu: 2.469 ± 1.327
3.704GlnPhe: 3.704 ± 1.991
1.852GlnGly: 1.852 ± 0.274
0.617GlnHis: 0.617 ± 0.332
3.704GlnIle: 3.704 ± 0.722
0.617GlnLys: 0.617 ± 0.332
5.556GlnLeu: 5.556 ± 1.717
0.617GlnMet: 0.617 ± 0.937
0.0GlnAsn: 0.0 ± 0.0
2.469GlnPro: 2.469 ± 1.327
1.235GlnGln: 1.235 ± 0.664
2.469GlnArg: 2.469 ± 1.327
3.086GlnSer: 3.086 ± 0.39
0.617GlnThr: 0.617 ± 0.937
2.469GlnVal: 2.469 ± 1.211
0.617GlnTrp: 0.617 ± 0.332
2.469GlnTyr: 2.469 ± 0.058
0.0GlnXaa: 0.0 ± 0.0
Arg
1.852ArgAla: 1.852 ± 0.274
0.0ArgCys: 0.0 ± 0.0
3.086ArgAsp: 3.086 ± 1.659
1.235ArgGlu: 1.235 ± 0.664
2.469ArgPhe: 2.469 ± 1.327
3.704ArgGly: 3.704 ± 3.086
1.235ArgHis: 1.235 ± 0.664
2.469ArgIle: 2.469 ± 0.058
3.704ArgLys: 3.704 ± 1.817
4.321ArgLeu: 4.321 ± 1.053
0.617ArgMet: 0.617 ± 0.332
2.469ArgAsn: 2.469 ± 0.058
4.938ArgPro: 4.938 ± 2.423
2.469ArgGln: 2.469 ± 1.327
4.938ArgArg: 4.938 ± 3.692
6.173ArgSer: 6.173 ± 0.49
4.321ArgThr: 4.321 ± 1.485
3.704ArgVal: 3.704 ± 0.722
0.0ArgTrp: 0.0 ± 0.0
1.852ArgTyr: 1.852 ± 0.995
0.0ArgXaa: 0.0 ± 0.0
Ser
5.556SerAla: 5.556 ± 2.091
0.617SerCys: 0.617 ± 0.332
4.938SerAsp: 4.938 ± 2.654
4.938SerGlu: 4.938 ± 2.654
8.025SerPhe: 8.025 ± 3.044
4.938SerGly: 4.938 ± 2.423
2.469SerHis: 2.469 ± 1.327
4.321SerIle: 4.321 ± 2.323
3.086SerLys: 3.086 ± 2.149
8.025SerLeu: 8.025 ± 3.044
4.938SerMet: 4.938 ± 1.385
1.852SerAsn: 1.852 ± 0.995
5.556SerPro: 5.556 ± 0.448
4.321SerGln: 4.321 ± 1.053
4.321SerArg: 4.321 ± 2.754
12.963SerSer: 12.963 ± 3.16
6.79SerThr: 6.79 ± 3.966
7.407SerVal: 7.407 ± 0.174
0.617SerTrp: 0.617 ± 0.332
4.938SerTyr: 4.938 ± 1.385
0.0SerXaa: 0.0 ± 0.0
Thr
3.704ThrAla: 3.704 ± 3.086
0.0ThrCys: 0.0 ± 0.0
4.321ThrAsp: 4.321 ± 1.485
2.469ThrGlu: 2.469 ± 1.211
3.086ThrPhe: 3.086 ± 0.39
5.556ThrGly: 5.556 ± 0.821
0.617ThrHis: 0.617 ± 0.332
3.086ThrIle: 3.086 ± 2.149
1.852ThrLys: 1.852 ± 0.274
8.025ThrLeu: 8.025 ± 1.775
1.852ThrMet: 1.852 ± 1.543
4.938ThrAsn: 4.938 ± 3.692
3.086ThrPro: 3.086 ± 0.39
0.0ThrGln: 0.0 ± 0.0
3.086ThrArg: 3.086 ± 0.879
5.556ThrSer: 5.556 ± 0.821
6.173ThrThr: 6.173 ± 4.297
4.321ThrVal: 4.321 ± 1.485
1.235ThrTrp: 1.235 ± 0.664
1.852ThrTyr: 1.852 ± 0.995
0.0ThrXaa: 0.0 ± 0.0
Val
1.235ValAla: 1.235 ± 1.875
0.617ValCys: 0.617 ± 0.937
3.704ValAsp: 3.704 ± 0.548
3.704ValGlu: 3.704 ± 1.991
4.321ValPhe: 4.321 ± 1.485
4.938ValGly: 4.938 ± 2.423
1.852ValHis: 1.852 ± 0.995
2.469ValIle: 2.469 ± 0.058
5.556ValLys: 5.556 ± 0.448
4.321ValLeu: 4.321 ± 2.323
3.086ValMet: 3.086 ± 0.39
2.469ValAsn: 2.469 ± 1.211
4.938ValPro: 4.938 ± 1.385
0.617ValGln: 0.617 ± 0.937
4.321ValArg: 4.321 ± 0.216
7.407ValSer: 7.407 ± 2.365
4.938ValThr: 4.938 ± 1.153
3.086ValVal: 3.086 ± 2.149
0.617ValTrp: 0.617 ± 0.937
1.235ValTyr: 1.235 ± 0.664
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.617TrpAsp: 0.617 ± 0.332
0.617TrpGlu: 0.617 ± 0.332
0.617TrpPhe: 0.617 ± 0.937
1.235TrpGly: 1.235 ± 0.664
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.852TrpLys: 1.852 ± 0.995
0.617TrpLeu: 0.617 ± 0.332
0.0TrpMet: 0.0 ± 0.0
0.617TrpAsn: 0.617 ± 0.332
0.0TrpPro: 0.0 ± 0.0
0.617TrpGln: 0.617 ± 0.937
1.852TrpArg: 1.852 ± 1.543
0.617TrpSer: 0.617 ± 0.332
0.617TrpThr: 0.617 ± 0.332
0.617TrpVal: 0.617 ± 0.332
0.0TrpTrp: 0.0 ± 0.0
0.617TrpTyr: 0.617 ± 0.332
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.469TyrAla: 2.469 ± 1.211
0.0TyrCys: 0.0 ± 0.0
1.852TyrAsp: 1.852 ± 0.274
0.0TyrGlu: 0.0 ± 0.0
1.235TyrPhe: 1.235 ± 0.664
1.235TyrGly: 1.235 ± 0.606
0.617TyrHis: 0.617 ± 0.937
3.086TyrIle: 3.086 ± 0.39
1.235TyrLys: 1.235 ± 0.664
4.321TyrLeu: 4.321 ± 2.323
1.235TyrMet: 1.235 ± 0.25
1.235TyrAsn: 1.235 ± 0.606
1.235TyrPro: 1.235 ± 0.664
1.235TyrGln: 1.235 ± 0.664
3.704TyrArg: 3.704 ± 1.991
4.938TyrSer: 4.938 ± 2.654
5.556TyrThr: 5.556 ± 0.448
1.852TyrVal: 1.852 ± 0.995
0.617TyrTrp: 0.617 ± 0.332
3.704TyrTyr: 3.704 ± 1.991
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1621 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski