Amino acid dipepetide frequency for Aureimonas altamirensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.468AlaAla: 18.468 ± 0.198	1.015AlaCys: 1.015 ± 0.027	7.509AlaAsp: 7.509 ± 0.102	8.036AlaGlu: 8.036 ± 0.101	4.82AlaPhe: 4.82 ± 0.067	12.054AlaGly: 12.054 ± 0.126	2.188AlaHis: 2.188 ± 0.046	6.905AlaIle: 6.905 ± 0.092	2.752AlaLys: 2.752 ± 0.057	14.182AlaLeu: 14.182 ± 0.143	4.102AlaMet: 4.102 ± 0.061	2.736AlaAsn: 2.736 ± 0.049	5.692AlaPro: 5.692 ± 0.076	3.681AlaGln: 3.681 ± 0.065	9.696AlaArg: 9.696 ± 0.107	6.668AlaSer: 6.668 ± 0.091	6.141AlaThr: 6.141 ± 0.077	9.291AlaVal: 9.291 ± 0.104	1.369AlaTrp: 1.369 ± 0.033	2.807AlaTyr: 2.807 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.82CysAla: 0.82 ± 0.029	0.099CysCys: 0.099 ± 0.01	0.48CysAsp: 0.48 ± 0.018	0.368CysGlu: 0.368 ± 0.018	0.286CysPhe: 0.286 ± 0.018	0.867CysGly: 0.867 ± 0.028	0.212CysHis: 0.212 ± 0.015	0.428CysIle: 0.428 ± 0.017	0.134CysLys: 0.134 ± 0.013	0.789CysLeu: 0.789 ± 0.024	0.168CysMet: 0.168 ± 0.012	0.183CysAsn: 0.183 ± 0.013	0.407CysPro: 0.407 ± 0.019	0.209CysGln: 0.209 ± 0.016	0.614CysArg: 0.614 ± 0.025	0.364CysSer: 0.364 ± 0.019	0.339CysThr: 0.339 ± 0.017	0.592CysVal: 0.592 ± 0.024	0.082CysTrp: 0.082 ± 0.01	0.16CysTyr: 0.16 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.648AspAla: 7.648 ± 0.087	0.454AspCys: 0.454 ± 0.017	3.34AspAsp: 3.34 ± 0.059	3.603AspGlu: 3.603 ± 0.063	2.169AspPhe: 2.169 ± 0.042	5.848AspGly: 5.848 ± 0.087	1.162AspHis: 1.162 ± 0.04	3.374AspIle: 3.374 ± 0.063	1.543AspLys: 1.543 ± 0.036	5.741AspLeu: 5.741 ± 0.076	1.496AspMet: 1.496 ± 0.039	1.235AspAsn: 1.235 ± 0.038	3.223AspPro: 3.223 ± 0.055	1.342AspGln: 1.342 ± 0.04	4.698AspArg: 4.698 ± 0.066	2.143AspSer: 2.143 ± 0.05	2.864AspThr: 2.864 ± 0.051	4.158AspVal: 4.158 ± 0.061	0.932AspTrp: 0.932 ± 0.027	1.487AspTyr: 1.487 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	8.346GluAla: 8.346 ± 0.114	0.322GluCys: 0.322 ± 0.016	2.928GluAsp: 2.928 ± 0.057	3.335GluGlu: 3.335 ± 0.066	1.699GluPhe: 1.699 ± 0.047	4.591GluGly: 4.591 ± 0.07	1.113GluHis: 1.113 ± 0.034	3.372GluIle: 3.372 ± 0.052	1.897GluLys: 1.897 ± 0.049	5.055GluLeu: 5.055 ± 0.066	1.429GluMet: 1.429 ± 0.042	1.412GluAsn: 1.412 ± 0.037	2.768GluPro: 2.768 ± 0.051	1.681GluGln: 1.681 ± 0.043	5.324GluArg: 5.324 ± 0.07	2.33GluSer: 2.33 ± 0.047	3.63GluThr: 3.63 ± 0.066	3.684GluVal: 3.684 ± 0.07	0.714GluTrp: 0.714 ± 0.026	0.903GluTyr: 0.903 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.669PheAla: 4.669 ± 0.068	0.333PheCys: 0.333 ± 0.018	2.686PheAsp: 2.686 ± 0.053	2.139PheGlu: 2.139 ± 0.045	1.515PhePhe: 1.515 ± 0.05	3.9PheGly: 3.9 ± 0.068	0.762PheHis: 0.762 ± 0.023	1.782PheIle: 1.782 ± 0.043	0.788PheLys: 0.788 ± 0.025	3.671PheLeu: 3.671 ± 0.064	0.858PheMet: 0.858 ± 0.027	0.937PheAsn: 0.937 ± 0.03	1.586PhePro: 1.586 ± 0.04	1.042PheGln: 1.042 ± 0.029	2.468PheArg: 2.468 ± 0.046	2.207PheSer: 2.207 ± 0.048	2.056PheThr: 2.056 ± 0.048	3.056PheVal: 3.056 ± 0.059	0.549PheTrp: 0.549 ± 0.025	0.85PheTyr: 0.85 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	9.99GlyAla: 9.99 ± 0.104	0.788GlyCys: 0.788 ± 0.032	4.612GlyAsp: 4.612 ± 0.073	4.897GlyGlu: 4.897 ± 0.077	3.864GlyPhe: 3.864 ± 0.067	7.93GlyGly: 7.93 ± 0.111	1.956GlyHis: 1.956 ± 0.048	5.083GlyIle: 5.083 ± 0.075	2.642GlyLys: 2.642 ± 0.059	9.486GlyLeu: 9.486 ± 0.102	2.47GlyMet: 2.47 ± 0.047	2.07GlyAsn: 2.07 ± 0.044	3.689GlyPro: 3.689 ± 0.061	3.072GlyGln: 3.072 ± 0.06	7.161GlyArg: 7.161 ± 0.091	4.702GlySer: 4.702 ± 0.061	4.864GlyThr: 4.864 ± 0.062	6.433GlyVal: 6.433 ± 0.071	1.311GlyTrp: 1.311 ± 0.036	2.232GlyTyr: 2.232 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.387HisAla: 2.387 ± 0.055	0.197HisCys: 0.197 ± 0.013	1.197HisAsp: 1.197 ± 0.04	1.002HisGlu: 1.002 ± 0.031	0.8HisPhe: 0.8 ± 0.029	1.991HisGly: 1.991 ± 0.044	0.564HisHis: 0.564 ± 0.03	0.909HisIle: 0.909 ± 0.031	0.416HisLys: 0.416 ± 0.02	1.982HisLeu: 1.982 ± 0.047	0.5HisMet: 0.5 ± 0.021	0.401HisAsn: 0.401 ± 0.018	1.272HisPro: 1.272 ± 0.035	0.495HisGln: 0.495 ± 0.021	1.595HisArg: 1.595 ± 0.044	0.916HisSer: 0.916 ± 0.032	0.762HisThr: 0.762 ± 0.025	1.553HisVal: 1.553 ± 0.043	0.286HisTrp: 0.286 ± 0.017	0.505HisTyr: 0.505 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.707IleAla: 7.707 ± 0.091	0.462IleCys: 0.462 ± 0.02	3.611IleAsp: 3.611 ± 0.056	3.373IleGlu: 3.373 ± 0.056	1.772IlePhe: 1.772 ± 0.052	5.365IleGly: 5.365 ± 0.086	0.974IleHis: 0.974 ± 0.026	2.131IleIle: 2.131 ± 0.056	1.024IleLys: 1.024 ± 0.034	4.939IleLeu: 4.939 ± 0.078	1.024IleMet: 1.024 ± 0.031	1.173IleAsn: 1.173 ± 0.035	2.314IlePro: 2.314 ± 0.044	1.2IleGln: 1.2 ± 0.036	3.433IleArg: 3.433 ± 0.053	2.623IleSer: 2.623 ± 0.057	2.307IleThr: 2.307 ± 0.043	4.923IleVal: 4.923 ± 0.069	0.561IleTrp: 0.561 ± 0.026	1.057IleTyr: 1.057 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	3.677LysAla: 3.677 ± 0.061	0.117LysCys: 0.117 ± 0.009	1.374LysAsp: 1.374 ± 0.038	1.255LysGlu: 1.255 ± 0.036	0.627LysPhe: 0.627 ± 0.028	2.328LysGly: 2.328 ± 0.051	0.434LysHis: 0.434 ± 0.022	1.163LysIle: 1.163 ± 0.035	0.748LysLys: 0.748 ± 0.03	2.55LysLeu: 2.55 ± 0.059	0.552LysMet: 0.552 ± 0.024	0.565LysAsn: 0.565 ± 0.024	1.62LysPro: 1.62 ± 0.043	0.681LysGln: 0.681 ± 0.026	2.048LysArg: 2.048 ± 0.044	1.353LysSer: 1.353 ± 0.037	1.462LysThr: 1.462 ± 0.04	2.027LysVal: 2.027 ± 0.052	0.238LysTrp: 0.238 ± 0.014	0.433LysTyr: 0.433 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	14.447LeuAla: 14.447 ± 0.156	0.868LeuCys: 0.868 ± 0.027	6.192LeuAsp: 6.192 ± 0.08	5.05LeuGlu: 5.05 ± 0.074	3.809LeuPhe: 3.809 ± 0.06	8.339LeuGly: 8.339 ± 0.102	1.812LeuHis: 1.812 ± 0.047	4.671LeuIle: 4.671 ± 0.076	2.95LeuLys: 2.95 ± 0.053	9.314LeuLeu: 9.314 ± 0.114	2.501LeuMet: 2.501 ± 0.041	2.319LeuAsn: 2.319 ± 0.051	5.752LeuPro: 5.752 ± 0.085	2.716LeuGln: 2.716 ± 0.055	6.969LeuArg: 6.969 ± 0.088	7.07LeuSer: 7.07 ± 0.075	5.575LeuThr: 5.575 ± 0.077	7.951LeuVal: 7.951 ± 0.102	1.127LeuTrp: 1.127 ± 0.036	2.105LeuTyr: 2.105 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	3.579MetAla: 3.579 ± 0.056	0.137MetCys: 0.137 ± 0.012	1.35MetAsp: 1.35 ± 0.034	1.3MetGlu: 1.3 ± 0.036	0.713MetPhe: 0.713 ± 0.028	1.901MetGly: 1.901 ± 0.04	0.448MetHis: 0.448 ± 0.022	1.34MetIle: 1.34 ± 0.033	0.848MetLys: 0.848 ± 0.029	2.543MetLeu: 2.543 ± 0.051	0.669MetMet: 0.669 ± 0.026	0.727MetAsn: 0.727 ± 0.028	1.658MetPro: 1.658 ± 0.04	0.901MetGln: 0.901 ± 0.027	2.012MetArg: 2.012 ± 0.045	1.692MetSer: 1.692 ± 0.043	1.79MetThr: 1.79 ± 0.04	1.795MetVal: 1.795 ± 0.037	0.183MetTrp: 0.183 ± 0.014	0.287MetTyr: 0.287 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.04AsnAla: 3.04 ± 0.054	0.194AsnCys: 0.194 ± 0.014	1.258AsnAsp: 1.258 ± 0.034	1.168AsnGlu: 1.168 ± 0.033	0.9AsnPhe: 0.9 ± 0.029	2.183AsnGly: 2.183 ± 0.048	0.425AsnHis: 0.425 ± 0.016	1.196AsnIle: 1.196 ± 0.032	0.493AsnLys: 0.493 ± 0.022	2.328AsnLeu: 2.328 ± 0.049	0.551AsnMet: 0.551 ± 0.023	0.553AsnAsn: 0.553 ± 0.026	1.654AsnPro: 1.654 ± 0.04	0.659AsnGln: 0.659 ± 0.023	1.834AsnArg: 1.834 ± 0.04	1.033AsnSer: 1.033 ± 0.033	1.073AsnThr: 1.073 ± 0.033	1.812AsnVal: 1.812 ± 0.044	0.378AsnTrp: 0.378 ± 0.019	0.619AsnTyr: 0.619 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	6.611ProAla: 6.611 ± 0.09	0.291ProCys: 0.291 ± 0.016	3.724ProAsp: 3.724 ± 0.059	3.643ProGlu: 3.643 ± 0.052	2.128ProPhe: 2.128 ± 0.044	4.788ProGly: 4.788 ± 0.07	1.042ProHis: 1.042 ± 0.034	2.28ProIle: 2.28 ± 0.046	1.175ProLys: 1.175 ± 0.037	4.859ProLeu: 4.859 ± 0.061	1.232ProMet: 1.232 ± 0.03	1.173ProAsn: 1.173 ± 0.035	2.371ProPro: 2.371 ± 0.048	1.758ProGln: 1.758 ± 0.041	2.926ProArg: 2.926 ± 0.057	2.802ProSer: 2.802 ± 0.056	2.432ProThr: 2.432 ± 0.047	4.345ProVal: 4.345 ± 0.066	0.588ProTrp: 0.588 ± 0.021	1.244ProTyr: 1.244 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.977GlnAla: 3.977 ± 0.068	0.163GlnCys: 0.163 ± 0.013	1.522GlnAsp: 1.522 ± 0.035	1.565GlnGlu: 1.565 ± 0.039	0.99GlnPhe: 0.99 ± 0.032	2.288GlnGly: 2.288 ± 0.043	0.527GlnHis: 0.527 ± 0.022	1.679GlnIle: 1.679 ± 0.031	0.94GlnLys: 0.94 ± 0.029	2.627GlnLeu: 2.627 ± 0.054	0.817GlnMet: 0.817 ± 0.026	0.797GlnAsn: 0.797 ± 0.03	1.777GlnPro: 1.777 ± 0.049	1.078GlnGln: 1.078 ± 0.034	2.472GlnArg: 2.472 ± 0.051	1.835GlnSer: 1.835 ± 0.045	1.676GlnThr: 1.676 ± 0.039	2.104GlnVal: 2.104 ± 0.047	0.373GlnTrp: 0.373 ± 0.018	0.527GlnTyr: 0.527 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	8.29ArgAla: 8.29 ± 0.098	0.472ArgCys: 0.472 ± 0.025	4.203ArgAsp: 4.203 ± 0.061	4.019ArgGlu: 4.019 ± 0.063	3.138ArgPhe: 3.138 ± 0.057	5.13ArgGly: 5.13 ± 0.063	1.897ArgHis: 1.897 ± 0.045	4.516ArgIle: 4.516 ± 0.061	2.139ArgLys: 2.139 ± 0.044	8.778ArgLeu: 8.778 ± 0.103	2.221ArgMet: 2.221 ± 0.05	1.964ArgAsn: 1.964 ± 0.039	4.018ArgPro: 4.018 ± 0.072	2.991ArgGln: 2.991 ± 0.05	6.663ArgArg: 6.663 ± 0.097	3.872ArgSer: 3.872 ± 0.059	3.626ArgThr: 3.626 ± 0.056	4.905ArgVal: 4.905 ± 0.066	0.986ArgTrp: 0.986 ± 0.032	1.747ArgTyr: 1.747 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.47SerAla: 6.47 ± 0.081	0.377SerCys: 0.377 ± 0.02	2.951SerAsp: 2.951 ± 0.054	2.684SerGlu: 2.684 ± 0.049	2.364SerPhe: 2.364 ± 0.05	5.681SerGly: 5.681 ± 0.074	1.083SerHis: 1.083 ± 0.028	3.006SerIle: 3.006 ± 0.052	1.131SerLys: 1.131 ± 0.033	5.431SerLeu: 5.431 ± 0.08	1.402SerMet: 1.402 ± 0.037	1.248SerAsn: 1.248 ± 0.031	2.72SerPro: 2.72 ± 0.047	1.583SerGln: 1.583 ± 0.04	3.836SerArg: 3.836 ± 0.068	2.792SerSer: 2.792 ± 0.06	2.618SerThr: 2.618 ± 0.045	4.118SerVal: 4.118 ± 0.065	0.674SerTrp: 0.674 ± 0.025	1.275SerTyr: 1.275 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	6.222ThrAla: 6.222 ± 0.082	0.376ThrCys: 0.376 ± 0.022	2.776ThrAsp: 2.776 ± 0.048	2.51ThrGlu: 2.51 ± 0.045	2.008ThrPhe: 2.008 ± 0.051	5.133ThrGly: 5.133 ± 0.066	1.014ThrHis: 1.014 ± 0.03	2.95ThrIle: 2.95 ± 0.051	1.045ThrLys: 1.045 ± 0.034	5.963ThrLeu: 5.963 ± 0.081	1.241ThrMet: 1.241 ± 0.033	1.126ThrAsn: 1.126 ± 0.029	3.239ThrPro: 3.239 ± 0.064	1.395ThrGln: 1.395 ± 0.033	3.577ThrArg: 3.577 ± 0.061	2.571ThrSer: 2.571 ± 0.06	2.582ThrThr: 2.582 ± 0.055	4.653ThrVal: 4.653 ± 0.074	0.566ThrTrp: 0.566 ± 0.023	1.195ThrTyr: 1.195 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	9.998ValAla: 9.998 ± 0.109	0.606ValCys: 0.606 ± 0.023	4.701ValAsp: 4.701 ± 0.066	4.845ValGlu: 4.845 ± 0.075	2.839ValPhe: 2.839 ± 0.053	5.988ValGly: 5.988 ± 0.084	1.369ValHis: 1.369 ± 0.039	3.738ValIle: 3.738 ± 0.065	1.724ValLys: 1.724 ± 0.047	7.487ValLeu: 7.487 ± 0.089	1.863ValMet: 1.863 ± 0.045	1.821ValAsn: 1.821 ± 0.038	3.868ValPro: 3.868 ± 0.053	2.018ValGln: 2.018 ± 0.042	5.293ValArg: 5.293 ± 0.07	4.637ValSer: 4.637 ± 0.069	4.58ValThr: 4.58 ± 0.071	6.274ValVal: 6.274 ± 0.083	0.883ValTrp: 0.883 ± 0.028	1.508ValTyr: 1.508 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.166TrpAla: 1.166 ± 0.035	0.12TrpCys: 0.12 ± 0.011	0.537TrpAsp: 0.537 ± 0.025	0.499TrpGlu: 0.499 ± 0.024	0.532TrpPhe: 0.532 ± 0.021	0.828TrpGly: 0.828 ± 0.027	0.299TrpHis: 0.299 ± 0.016	0.577TrpIle: 0.577 ± 0.024	0.383TrpLys: 0.383 ± 0.021	1.564TrpLeu: 1.564 ± 0.046	0.334TrpMet: 0.334 ± 0.019	0.418TrpAsn: 0.418 ± 0.019	0.707TrpPro: 0.707 ± 0.028	0.583TrpGln: 0.583 ± 0.024	1.139TrpArg: 1.139 ± 0.037	0.727TrpSer: 0.727 ± 0.026	0.756TrpThr: 0.756 ± 0.027	0.684TrpVal: 0.684 ± 0.023	0.229TrpTrp: 0.229 ± 0.016	0.267TrpTyr: 0.267 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.599TyrAla: 2.599 ± 0.05	0.211TyrCys: 0.211 ± 0.013	1.508TyrAsp: 1.508 ± 0.044	1.244TyrGlu: 1.244 ± 0.035	0.878TyrPhe: 0.878 ± 0.029	2.12TyrGly: 2.12 ± 0.046	0.447TyrHis: 0.447 ± 0.022	0.874TyrIle: 0.874 ± 0.027	0.478TyrLys: 0.478 ± 0.022	2.249TyrLeu: 2.249 ± 0.042	0.441TyrMet: 0.441 ± 0.018	0.496TyrAsn: 0.496 ± 0.019	1.078TyrPro: 1.078 ± 0.03	0.652TyrGln: 0.652 ± 0.024	1.818TyrArg: 1.818 ± 0.041	1.108TyrSer: 1.108 ± 0.029	1.007TyrThr: 1.007 ± 0.035	1.68TyrVal: 1.68 ± 0.04	0.321TyrTrp: 0.321 ± 0.018	0.572TyrTyr: 0.572 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3519 proteins (1115690 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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