Amino acid dipepetide frequency for Flavivirga eckloniae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.764AlaAla: 3.764 ± 0.096	0.577AlaCys: 0.577 ± 0.021	3.078AlaAsp: 3.078 ± 0.07	3.454AlaGlu: 3.454 ± 0.068	3.281AlaPhe: 3.281 ± 0.047	3.707AlaGly: 3.707 ± 0.055	1.015AlaHis: 1.015 ± 0.026	5.167AlaIle: 5.167 ± 0.063	4.288AlaLys: 4.288 ± 0.073	5.914AlaLeu: 5.914 ± 0.071	1.24AlaMet: 1.24 ± 0.029	3.612AlaAsn: 3.612 ± 0.052	1.971AlaPro: 1.971 ± 0.063	2.011AlaGln: 2.011 ± 0.034	1.777AlaArg: 1.777 ± 0.042	4.361AlaSer: 4.361 ± 0.071	3.649AlaThr: 3.649 ± 0.087	3.567AlaVal: 3.567 ± 0.058	0.688AlaTrp: 0.688 ± 0.042	2.485AlaTyr: 2.485 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.401CysAla: 0.401 ± 0.016	0.09CysCys: 0.09 ± 0.009	0.518CysAsp: 0.518 ± 0.048	0.464CysGlu: 0.464 ± 0.018	0.429CysPhe: 0.429 ± 0.017	0.567CysGly: 0.567 ± 0.022	0.202CysHis: 0.202 ± 0.013	0.611CysIle: 0.611 ± 0.021	0.543CysLys: 0.543 ± 0.02	0.686CysLeu: 0.686 ± 0.022	0.16CysMet: 0.16 ± 0.011	0.443CysAsn: 0.443 ± 0.02	0.298CysPro: 0.298 ± 0.018	0.208CysGln: 0.208 ± 0.018	0.193CysArg: 0.193 ± 0.01	0.644CysSer: 0.644 ± 0.047	0.458CysThr: 0.458 ± 0.029	0.428CysVal: 0.428 ± 0.015	0.078CysTrp: 0.078 ± 0.008	0.367CysTyr: 0.367 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.745AspAla: 3.745 ± 0.049	0.502AspCys: 0.502 ± 0.05	3.228AspAsp: 3.228 ± 0.048	3.518AspGlu: 3.518 ± 0.045	3.687AspPhe: 3.687 ± 0.053	4.133AspGly: 4.133 ± 0.17	0.945AspHis: 0.945 ± 0.023	5.0AspIle: 5.0 ± 0.055	4.078AspLys: 4.078 ± 0.058	5.278AspLeu: 5.278 ± 0.063	1.144AspMet: 1.144 ± 0.027	3.555AspAsn: 3.555 ± 0.06	1.864AspPro: 1.864 ± 0.06	1.37AspGln: 1.37 ± 0.031	1.779AspArg: 1.779 ± 0.032	3.383AspSer: 3.383 ± 0.054	2.933AspThr: 2.933 ± 0.046	3.874AspVal: 3.874 ± 0.055	0.802AspTrp: 0.802 ± 0.026	2.97AspTyr: 2.97 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.361GluAla: 4.361 ± 0.072	0.344GluCys: 0.344 ± 0.023	3.632GluAsp: 3.632 ± 0.048	4.301GluGlu: 4.301 ± 0.08	2.908GluPhe: 2.908 ± 0.052	3.711GluGly: 3.711 ± 0.058	1.168GluHis: 1.168 ± 0.027	5.009GluIle: 5.009 ± 0.056	5.394GluLys: 5.394 ± 0.071	5.9GluLeu: 5.9 ± 0.076	1.303GluMet: 1.303 ± 0.03	4.614GluAsn: 4.614 ± 0.067	1.574GluPro: 1.574 ± 0.036	2.076GluGln: 2.076 ± 0.038	2.304GluArg: 2.304 ± 0.044	3.569GluSer: 3.569 ± 0.051	3.891GluThr: 3.891 ± 0.052	4.024GluVal: 4.024 ± 0.054	0.638GluTrp: 0.638 ± 0.02	2.289GluTyr: 2.289 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	2.613PheAla: 2.613 ± 0.043	0.432PheCys: 0.432 ± 0.016	3.232PheAsp: 3.232 ± 0.051	3.315PheGlu: 3.315 ± 0.051	2.716PhePhe: 2.716 ± 0.046	3.481PheGly: 3.481 ± 0.056	0.827PheHis: 0.827 ± 0.022	3.927PheIle: 3.927 ± 0.052	4.237PheLys: 4.237 ± 0.061	4.58PheLeu: 4.58 ± 0.069	1.047PheMet: 1.047 ± 0.029	3.946PheAsn: 3.946 ± 0.055	1.653PhePro: 1.653 ± 0.03	1.456PheGln: 1.456 ± 0.032	1.627PheArg: 1.627 ± 0.033	4.226PheSer: 4.226 ± 0.057	3.084PheThr: 3.084 ± 0.051	2.995PheVal: 2.995 ± 0.055	0.603PheTrp: 0.603 ± 0.019	2.196PheTyr: 2.196 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.068GlyAla: 4.068 ± 0.064	0.617GlyCys: 0.617 ± 0.029	3.748GlyAsp: 3.748 ± 0.082	3.51GlyGlu: 3.51 ± 0.051	3.673GlyPhe: 3.673 ± 0.059	4.549GlyGly: 4.549 ± 0.074	1.179GlyHis: 1.179 ± 0.032	5.238GlyIle: 5.238 ± 0.058	4.68GlyLys: 4.68 ± 0.065	5.635GlyLeu: 5.635 ± 0.068	1.388GlyMet: 1.388 ± 0.034	3.993GlyAsn: 3.993 ± 0.063	1.373GlyPro: 1.373 ± 0.034	1.763GlyGln: 1.763 ± 0.035	2.009GlyArg: 2.009 ± 0.037	4.138GlySer: 4.138 ± 0.071	4.355GlyThr: 4.355 ± 0.132	4.42GlyVal: 4.42 ± 0.077	0.865GlyTrp: 0.865 ± 0.027	2.95GlyTyr: 2.95 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	0.984HisAla: 0.984 ± 0.027	0.172HisCys: 0.172 ± 0.01	0.935HisAsp: 0.935 ± 0.023	0.947HisGlu: 0.947 ± 0.027	1.138HisPhe: 1.138 ± 0.024	1.101HisGly: 1.101 ± 0.028	0.492HisHis: 0.492 ± 0.02	1.526HisIle: 1.526 ± 0.029	1.264HisLys: 1.264 ± 0.03	1.754HisLeu: 1.754 ± 0.039	0.337HisMet: 0.337 ± 0.015	1.052HisAsn: 1.052 ± 0.023	0.819HisPro: 0.819 ± 0.023	0.611HisGln: 0.611 ± 0.019	0.601HisArg: 0.601 ± 0.02	1.031HisSer: 1.031 ± 0.028	1.019HisThr: 1.019 ± 0.024	1.025HisVal: 1.025 ± 0.027	0.27HisTrp: 0.27 ± 0.013	0.88HisTyr: 0.88 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.055IleAla: 5.055 ± 0.058	0.65IleCys: 0.65 ± 0.02	5.147IleAsp: 5.147 ± 0.057	5.609IleGlu: 5.609 ± 0.069	3.524IlePhe: 3.524 ± 0.047	5.058IleGly: 5.058 ± 0.068	1.328IleHis: 1.328 ± 0.029	6.143IleIle: 6.143 ± 0.066	6.419IleLys: 6.419 ± 0.083	6.71IleLeu: 6.71 ± 0.071	1.337IleMet: 1.337 ± 0.029	5.48IleAsn: 5.48 ± 0.067	3.188IlePro: 3.188 ± 0.04	2.341IleGln: 2.341 ± 0.038	2.533IleArg: 2.533 ± 0.038	5.962IleSer: 5.962 ± 0.068	5.247IleThr: 5.247 ± 0.082	4.874IleVal: 4.874 ± 0.058	0.736IleTrp: 0.736 ± 0.023	2.961IleTyr: 2.961 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	4.95LysAla: 4.95 ± 0.084	0.355LysCys: 0.355 ± 0.016	4.701LysAsp: 4.701 ± 0.057	6.038LysGlu: 6.038 ± 0.078	2.882LysPhe: 2.882 ± 0.048	4.644LysGly: 4.644 ± 0.063	1.6LysHis: 1.6 ± 0.034	6.036LysIle: 6.036 ± 0.07	6.922LysLys: 6.922 ± 0.095	6.641LysLeu: 6.641 ± 0.078	1.825LysMet: 1.825 ± 0.036	5.465LysAsn: 5.465 ± 0.079	2.484LysPro: 2.484 ± 0.044	2.792LysGln: 2.792 ± 0.047	3.077LysArg: 3.077 ± 0.053	4.826LysSer: 4.826 ± 0.063	5.034LysThr: 5.034 ± 0.065	4.529LysVal: 4.529 ± 0.062	0.875LysTrp: 0.875 ± 0.026	3.14LysTyr: 3.14 ± 0.056	0.0LysXaa: 0.0 ± 0.0
Leu	5.065LeuAla: 5.065 ± 0.074	0.683LeuCys: 0.683 ± 0.021	5.041LeuAsp: 5.041 ± 0.062	5.938LeuGlu: 5.938 ± 0.071	4.851LeuPhe: 4.851 ± 0.066	5.657LeuGly: 5.657 ± 0.061	1.507LeuHis: 1.507 ± 0.03	7.008LeuIle: 7.008 ± 0.085	8.011LeuLys: 8.011 ± 0.087	8.263LeuLeu: 8.263 ± 0.091	1.801LeuMet: 1.801 ± 0.034	6.165LeuAsn: 6.165 ± 0.066	3.403LeuPro: 3.403 ± 0.054	2.806LeuGln: 2.806 ± 0.045	2.952LeuArg: 2.952 ± 0.05	6.749LeuSer: 6.749 ± 0.075	5.116LeuThr: 5.116 ± 0.061	5.21LeuVal: 5.21 ± 0.059	0.834LeuTrp: 0.834 ± 0.022	3.35LeuTyr: 3.35 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	1.388MetAla: 1.388 ± 0.033	0.135MetCys: 0.135 ± 0.009	1.024MetAsp: 1.024 ± 0.024	1.131MetGlu: 1.131 ± 0.03	0.939MetPhe: 0.939 ± 0.032	1.248MetGly: 1.248 ± 0.031	0.372MetHis: 0.372 ± 0.017	1.396MetIle: 1.396 ± 0.031	1.958MetLys: 1.958 ± 0.033	1.789MetLeu: 1.789 ± 0.034	0.45MetMet: 0.45 ± 0.018	1.225MetAsn: 1.225 ± 0.027	0.791MetPro: 0.791 ± 0.02	0.714MetGln: 0.714 ± 0.02	0.765MetArg: 0.765 ± 0.022	1.344MetSer: 1.344 ± 0.028	1.085MetThr: 1.085 ± 0.031	1.239MetVal: 1.239 ± 0.028	0.161MetTrp: 0.161 ± 0.01	0.724MetTyr: 0.724 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.918AsnAla: 3.918 ± 0.078	0.534AsnCys: 0.534 ± 0.034	3.801AsnAsp: 3.801 ± 0.054	3.969AsnGlu: 3.969 ± 0.053	3.105AsnPhe: 3.105 ± 0.046	4.6AsnGly: 4.6 ± 0.09	1.197AsnHis: 1.197 ± 0.029	5.52AsnIle: 5.52 ± 0.063	5.014AsnLys: 5.014 ± 0.067	5.661AsnLeu: 5.661 ± 0.072	1.343AsnMet: 1.343 ± 0.032	4.911AsnAsn: 4.911 ± 0.078	2.893AsnPro: 2.893 ± 0.051	2.228AsnGln: 2.228 ± 0.046	2.242AsnArg: 2.242 ± 0.04	4.296AsnSer: 4.296 ± 0.064	4.414AsnThr: 4.414 ± 0.065	3.822AsnVal: 3.822 ± 0.067	0.91AsnTrp: 0.91 ± 0.025	3.172AsnTyr: 3.172 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	1.723ProAla: 1.723 ± 0.039	0.219ProCys: 0.219 ± 0.012	2.178ProAsp: 2.178 ± 0.043	2.786ProGlu: 2.786 ± 0.046	1.861ProPhe: 1.861 ± 0.035	1.936ProGly: 1.936 ± 0.039	0.593ProHis: 0.593 ± 0.016	2.742ProIle: 2.742 ± 0.043	2.551ProLys: 2.551 ± 0.046	2.95ProLeu: 2.95 ± 0.059	0.6ProMet: 0.6 ± 0.02	2.541ProAsn: 2.541 ± 0.06	0.887ProPro: 0.887 ± 0.031	1.018ProGln: 1.018 ± 0.023	0.93ProArg: 0.93 ± 0.024	2.206ProSer: 2.206 ± 0.04	1.982ProThr: 1.982 ± 0.046	2.258ProVal: 2.258 ± 0.042	0.389ProTrp: 0.389 ± 0.014	1.409ProTyr: 1.409 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	1.811GlnAla: 1.811 ± 0.035	0.204GlnCys: 0.204 ± 0.012	1.674GlnAsp: 1.674 ± 0.03	2.05GlnGlu: 2.05 ± 0.041	1.586GlnPhe: 1.586 ± 0.034	1.733GlnGly: 1.733 ± 0.031	0.56GlnHis: 0.56 ± 0.019	2.472GlnIle: 2.472 ± 0.037	2.413GlnLys: 2.413 ± 0.042	3.127GlnLeu: 3.127 ± 0.047	0.685GlnMet: 0.685 ± 0.023	2.13GlnAsn: 2.13 ± 0.035	1.002GlnPro: 1.002 ± 0.03	1.174GlnGln: 1.174 ± 0.034	1.076GlnArg: 1.076 ± 0.032	1.85GlnSer: 1.85 ± 0.035	1.828GlnThr: 1.828 ± 0.042	1.82GlnVal: 1.82 ± 0.034	0.337GlnTrp: 0.337 ± 0.022	1.306GlnTyr: 1.306 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	1.993ArgAla: 1.993 ± 0.042	0.199ArgCys: 0.199 ± 0.01	1.817ArgAsp: 1.817 ± 0.037	1.934ArgGlu: 1.934 ± 0.042	1.944ArgPhe: 1.944 ± 0.036	1.954ArgGly: 1.954 ± 0.038	0.625ArgHis: 0.625 ± 0.021	2.843ArgIle: 2.843 ± 0.048	2.527ArgLys: 2.527 ± 0.046	3.258ArgLeu: 3.258 ± 0.054	0.777ArgMet: 0.777 ± 0.025	2.048ArgAsn: 2.048 ± 0.04	1.005ArgPro: 1.005 ± 0.025	0.975ArgGln: 0.975 ± 0.027	1.265ArgArg: 1.265 ± 0.038	1.913ArgSer: 1.913 ± 0.041	1.858ArgThr: 1.858 ± 0.044	2.058ArgVal: 2.058 ± 0.04	0.438ArgTrp: 0.438 ± 0.018	1.515ArgTyr: 1.515 ± 0.03	0.0ArgXaa: 0.0 ± 0.0
Ser	3.659SerAla: 3.659 ± 0.074	0.684SerCys: 0.684 ± 0.024	3.698SerAsp: 3.698 ± 0.049	3.935SerGlu: 3.935 ± 0.053	4.05SerPhe: 4.05 ± 0.062	4.877SerGly: 4.877 ± 0.084	1.188SerHis: 1.188 ± 0.03	5.785SerIle: 5.785 ± 0.07	5.476SerLys: 5.476 ± 0.072	5.99SerLeu: 5.99 ± 0.06	1.228SerMet: 1.228 ± 0.03	4.573SerAsn: 4.573 ± 0.068	2.179SerPro: 2.179 ± 0.044	2.093SerGln: 2.093 ± 0.036	2.149SerArg: 2.149 ± 0.041	4.623SerSer: 4.623 ± 0.072	3.664SerThr: 3.664 ± 0.054	3.997SerVal: 3.997 ± 0.054	0.819SerTrp: 0.819 ± 0.026	2.877SerTyr: 2.877 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	3.459ThrAla: 3.459 ± 0.07	0.422ThrCys: 0.422 ± 0.029	3.544ThrAsp: 3.544 ± 0.105	3.37ThrGlu: 3.37 ± 0.057	3.188ThrPhe: 3.188 ± 0.059	4.166ThrGly: 4.166 ± 0.077	1.078ThrHis: 1.078 ± 0.024	5.402ThrIle: 5.402 ± 0.072	4.106ThrLys: 4.106 ± 0.062	5.525ThrLeu: 5.525 ± 0.068	0.99ThrMet: 0.99 ± 0.025	3.978ThrAsn: 3.978 ± 0.067	2.546ThrPro: 2.546 ± 0.044	1.789ThrGln: 1.789 ± 0.037	1.717ThrArg: 1.717 ± 0.029	4.208ThrSer: 4.208 ± 0.066	3.894ThrThr: 3.894 ± 0.084	3.949ThrVal: 3.949 ± 0.099	0.684ThrTrp: 0.684 ± 0.021	2.648ThrTyr: 2.648 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	3.659ValAla: 3.659 ± 0.064	0.506ValCys: 0.506 ± 0.018	3.609ValAsp: 3.609 ± 0.055	3.715ValGlu: 3.715 ± 0.052	3.46ValPhe: 3.46 ± 0.046	3.63ValGly: 3.63 ± 0.047	0.923ValHis: 0.923 ± 0.024	4.785ValIle: 4.785 ± 0.063	4.467ValLys: 4.467 ± 0.059	5.906ValLeu: 5.906 ± 0.075	1.175ValMet: 1.175 ± 0.031	3.824ValAsn: 3.824 ± 0.047	2.13ValPro: 2.13 ± 0.039	1.593ValGln: 1.593 ± 0.031	1.919ValArg: 1.919 ± 0.038	4.719ValSer: 4.719 ± 0.066	3.924ValThr: 3.924 ± 0.103	3.986ValVal: 3.986 ± 0.066	0.647ValTrp: 0.647 ± 0.02	2.499ValTyr: 2.499 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.602TrpAla: 0.602 ± 0.018	0.115TrpCys: 0.115 ± 0.009	0.735TrpAsp: 0.735 ± 0.028	0.722TrpGlu: 0.722 ± 0.023	0.58TrpPhe: 0.58 ± 0.019	0.759TrpGly: 0.759 ± 0.024	0.274TrpHis: 0.274 ± 0.014	0.798TrpIle: 0.798 ± 0.025	0.886TrpLys: 0.886 ± 0.028	1.004TrpLeu: 1.004 ± 0.03	0.297TrpMet: 0.297 ± 0.014	0.869TrpAsn: 0.869 ± 0.044	0.246TrpPro: 0.246 ± 0.011	0.427TrpGln: 0.427 ± 0.018	0.394TrpArg: 0.394 ± 0.015	0.72TrpSer: 0.72 ± 0.021	0.648TrpThr: 0.648 ± 0.021	0.727TrpVal: 0.727 ± 0.022	0.184TrpTrp: 0.184 ± 0.011	0.499TrpTyr: 0.499 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.392TyrAla: 2.392 ± 0.037	0.348TyrCys: 0.348 ± 0.015	2.447TyrAsp: 2.447 ± 0.051	2.306TyrGlu: 2.306 ± 0.043	2.388TyrPhe: 2.388 ± 0.039	2.641TyrGly: 2.641 ± 0.039	0.889TyrHis: 0.889 ± 0.028	2.893TyrIle: 2.893 ± 0.047	3.583TyrLys: 3.583 ± 0.053	3.836TyrLeu: 3.836 ± 0.057	0.75TyrMet: 0.75 ± 0.019	3.129TyrAsn: 3.129 ± 0.05	1.452TyrPro: 1.452 ± 0.031	1.392TyrGln: 1.392 ± 0.035	1.638TyrArg: 1.638 ± 0.035	2.777TyrSer: 2.777 ± 0.047	2.578TyrThr: 2.578 ± 0.047	2.272TyrVal: 2.272 ± 0.042	0.527TyrTrp: 0.527 ± 0.02	1.998TyrTyr: 1.998 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4547 proteins (1645158 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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