Amino acid dipepetide frequency for Pepper cryptic virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.865AlaAla: 7.865 ± 1.16
1.124AlaCys: 1.124 ± 0.817
2.247AlaAsp: 2.247 ± 0.114
0.0AlaGlu: 0.0 ± 0.0
6.742AlaPhe: 6.742 ± 1.177
3.371AlaGly: 3.371 ± 2.108
1.124AlaHis: 1.124 ± 0.817
7.865AlaIle: 7.865 ± 0.359
3.371AlaLys: 3.371 ± 2.108
3.371AlaLeu: 3.371 ± 0.932
0.0AlaMet: 0.0 ± 0.587
3.371AlaAsn: 3.371 ± 0.932
2.247AlaPro: 2.247 ± 1.634
2.247AlaGln: 2.247 ± 0.114
1.124AlaArg: 1.124 ± 0.817
5.618AlaSer: 5.618 ± 1.046
6.742AlaThr: 6.742 ± 1.863
3.371AlaVal: 3.371 ± 2.108
2.247AlaTrp: 2.247 ± 1.634
5.618AlaTyr: 5.618 ± 0.474
0.0AlaXaa: 0.0 ± 0.0
Cys
1.124CysAla: 1.124 ± 0.817
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.124CysGlu: 1.124 ± 0.817
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
1.124CysHis: 1.124 ± 0.703
1.124CysIle: 1.124 ± 0.703
1.124CysLys: 1.124 ± 0.703
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.124CysSer: 1.124 ± 0.817
1.124CysThr: 1.124 ± 0.817
0.0CysVal: 0.0 ± 0.0
1.124CysTrp: 1.124 ± 0.817
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.371AspAla: 3.371 ± 0.588
0.0AspCys: 0.0 ± 0.0
6.742AspAsp: 6.742 ± 1.863
1.124AspGlu: 1.124 ± 0.703
2.247AspPhe: 2.247 ± 0.114
2.247AspGly: 2.247 ± 1.406
0.0AspHis: 0.0 ± 0.0
1.124AspIle: 1.124 ± 0.703
3.371AspLys: 3.371 ± 0.588
5.618AspLeu: 5.618 ± 0.474
0.0AspMet: 0.0 ± 0.0
4.494AspAsn: 4.494 ± 1.749
2.247AspPro: 2.247 ± 0.114
3.371AspGln: 3.371 ± 0.588
2.247AspArg: 2.247 ± 1.634
2.247AspSer: 2.247 ± 0.114
2.247AspThr: 2.247 ± 1.634
4.494AspVal: 4.494 ± 1.291
4.494AspTrp: 4.494 ± 1.749
2.247AspTyr: 2.247 ± 0.114
0.0AspXaa: 0.0 ± 0.0
Glu
4.494GluAla: 4.494 ± 1.749
0.0GluCys: 0.0 ± 0.0
2.247GluAsp: 2.247 ± 1.634
4.494GluGlu: 4.494 ± 2.811
1.124GluPhe: 1.124 ± 0.817
2.247GluGly: 2.247 ± 1.406
2.247GluHis: 2.247 ± 1.406
5.618GluIle: 5.618 ± 1.994
2.247GluLys: 2.247 ± 1.406
3.371GluLeu: 3.371 ± 0.932
1.124GluMet: 1.124 ± 0.703
4.494GluAsn: 4.494 ± 1.749
1.124GluPro: 1.124 ± 0.817
1.124GluGln: 1.124 ± 0.703
2.247GluArg: 2.247 ± 1.634
3.371GluSer: 3.371 ± 2.108
4.494GluThr: 4.494 ± 0.229
4.494GluVal: 4.494 ± 0.229
0.0GluTrp: 0.0 ± 0.0
2.247GluTyr: 2.247 ± 0.114
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
4.494PheAsp: 4.494 ± 1.291
2.247PheGlu: 2.247 ± 1.406
0.0PhePhe: 0.0 ± 0.0
2.247PheGly: 2.247 ± 0.114
1.124PheHis: 1.124 ± 0.703
5.618PheIle: 5.618 ± 1.994
3.371PheLys: 3.371 ± 0.588
4.494PheLeu: 4.494 ± 1.749
0.0PheMet: 0.0 ± 0.0
3.371PheAsn: 3.371 ± 0.932
3.371PhePro: 3.371 ± 0.932
2.247PheGln: 2.247 ± 0.114
1.124PheArg: 1.124 ± 0.817
2.247PheSer: 2.247 ± 0.114
5.618PheThr: 5.618 ± 4.086
1.124PheVal: 1.124 ± 0.817
0.0PheTrp: 0.0 ± 0.0
1.124PheTyr: 1.124 ± 0.817
0.0PheXaa: 0.0 ± 0.0
Gly
2.247GlyAla: 2.247 ± 1.634
0.0GlyCys: 0.0 ± 0.0
5.618GlyAsp: 5.618 ± 1.994
1.124GlyGlu: 1.124 ± 0.703
1.124GlyPhe: 1.124 ± 0.703
2.247GlyGly: 2.247 ± 1.406
1.124GlyHis: 1.124 ± 0.703
3.371GlyIle: 3.371 ± 0.588
0.0GlyLys: 0.0 ± 0.0
5.618GlyLeu: 5.618 ± 1.994
0.0GlyMet: 0.0 ± 0.0
1.124GlyAsn: 1.124 ± 0.817
1.124GlyPro: 1.124 ± 0.817
1.124GlyGln: 1.124 ± 0.703
5.618GlyArg: 5.618 ± 1.994
2.247GlySer: 2.247 ± 1.406
4.494GlyThr: 4.494 ± 0.229
3.371GlyVal: 3.371 ± 0.932
2.247GlyTrp: 2.247 ± 1.406
4.494GlyTyr: 4.494 ± 2.811
0.0GlyXaa: 0.0 ± 0.0
His
2.247HisAla: 2.247 ± 1.406
0.0HisCys: 0.0 ± 0.0
2.247HisAsp: 2.247 ± 1.634
0.0HisGlu: 0.0 ± 0.0
2.247HisPhe: 2.247 ± 0.114
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
3.371HisIle: 3.371 ± 0.932
3.371HisLys: 3.371 ± 2.108
1.124HisLeu: 1.124 ± 0.703
0.0HisMet: 0.0 ± 0.0
1.124HisAsn: 1.124 ± 0.817
2.247HisPro: 2.247 ± 1.406
1.124HisGln: 1.124 ± 0.817
3.371HisArg: 3.371 ± 0.588
2.247HisSer: 2.247 ± 0.114
2.247HisThr: 2.247 ± 0.114
2.247HisVal: 2.247 ± 1.406
0.0HisTrp: 0.0 ± 0.0
1.124HisTyr: 1.124 ± 0.703
0.0HisXaa: 0.0 ± 0.0
Ile
5.618IleAla: 5.618 ± 1.994
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
5.618IleGlu: 5.618 ± 1.994
2.247IlePhe: 2.247 ± 1.634
4.494IleGly: 4.494 ± 1.749
3.371IleHis: 3.371 ± 2.108
7.865IleIle: 7.865 ± 2.68
3.371IleLys: 3.371 ± 0.588
5.618IleLeu: 5.618 ± 1.046
0.0IleMet: 0.0 ± 0.0
2.247IleAsn: 2.247 ± 1.406
2.247IlePro: 2.247 ± 0.114
2.247IleGln: 2.247 ± 0.114
7.865IleArg: 7.865 ± 2.68
6.742IleSer: 6.742 ± 1.177
3.371IleThr: 3.371 ± 0.588
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
5.618IleTyr: 5.618 ± 1.994
0.0IleXaa: 0.0 ± 0.0
Lys
2.247LysAla: 2.247 ± 1.406
1.124LysCys: 1.124 ± 0.703
1.124LysAsp: 1.124 ± 0.703
2.247LysGlu: 2.247 ± 1.634
0.0LysPhe: 0.0 ± 0.0
3.371LysGly: 3.371 ± 2.108
1.124LysHis: 1.124 ± 0.703
2.247LysIle: 2.247 ± 1.634
1.124LysLys: 1.124 ± 0.703
4.494LysLeu: 4.494 ± 0.229
0.0LysMet: 0.0 ± 0.0
1.124LysAsn: 1.124 ± 0.703
1.124LysPro: 1.124 ± 0.817
0.0LysGln: 0.0 ± 0.0
2.247LysArg: 2.247 ± 1.406
4.494LysSer: 4.494 ± 2.811
3.371LysThr: 3.371 ± 2.108
2.247LysVal: 2.247 ± 1.406
1.124LysTrp: 1.124 ± 0.703
2.247LysTyr: 2.247 ± 1.634
0.0LysXaa: 0.0 ± 0.0
Leu
4.494LeuAla: 4.494 ± 1.749
1.124LeuCys: 1.124 ± 0.817
2.247LeuAsp: 2.247 ± 0.114
4.494LeuGlu: 4.494 ± 0.229
3.371LeuPhe: 3.371 ± 0.932
4.494LeuGly: 4.494 ± 1.291
1.124LeuHis: 1.124 ± 0.817
3.371LeuIle: 3.371 ± 2.108
2.247LeuLys: 2.247 ± 0.114
11.236LeuLeu: 11.236 ± 0.572
0.0LeuMet: 0.0 ± 0.0
7.865LeuAsn: 7.865 ± 0.359
5.618LeuPro: 5.618 ± 1.046
2.247LeuGln: 2.247 ± 1.634
4.494LeuArg: 4.494 ± 0.229
5.618LeuSer: 5.618 ± 0.474
7.865LeuThr: 7.865 ± 0.359
7.865LeuVal: 7.865 ± 3.399
3.371LeuTrp: 3.371 ± 0.588
3.371LeuTyr: 3.371 ± 0.588
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.124MetAsp: 1.124 ± 0.703
0.0MetGlu: 0.0 ± 0.0
1.124MetPhe: 1.124 ± 0.817
1.124MetGly: 1.124 ± 0.817
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.124MetPro: 1.124 ± 0.703
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.247MetSer: 2.247 ± 0.114
0.0MetThr: 0.0 ± 0.0
1.124MetVal: 1.124 ± 0.703
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.124AsnAla: 1.124 ± 0.817
1.124AsnCys: 1.124 ± 0.703
0.0AsnAsp: 0.0 ± 0.0
2.247AsnGlu: 2.247 ± 1.634
2.247AsnPhe: 2.247 ± 1.634
1.124AsnGly: 1.124 ± 0.703
3.371AsnHis: 3.371 ± 0.932
1.124AsnIle: 1.124 ± 0.817
2.247AsnLys: 2.247 ± 1.406
1.124AsnLeu: 1.124 ± 0.817
0.0AsnMet: 0.0 ± 0.0
1.124AsnAsn: 1.124 ± 0.817
3.371AsnPro: 3.371 ± 0.588
0.0AsnGln: 0.0 ± 0.0
2.247AsnArg: 2.247 ± 0.114
5.618AsnSer: 5.618 ± 2.566
2.247AsnThr: 2.247 ± 1.634
3.371AsnVal: 3.371 ± 0.932
0.0AsnTrp: 0.0 ± 0.0
7.865AsnTyr: 7.865 ± 1.879
0.0AsnXaa: 0.0 ± 0.0
Pro
2.247ProAla: 2.247 ± 0.114
1.124ProCys: 1.124 ± 0.817
4.494ProAsp: 4.494 ± 1.291
5.618ProGlu: 5.618 ± 1.994
4.494ProPhe: 4.494 ± 0.229
1.124ProGly: 1.124 ± 0.817
2.247ProHis: 2.247 ± 0.114
2.247ProIle: 2.247 ± 0.114
1.124ProLys: 1.124 ± 0.817
3.371ProLeu: 3.371 ± 0.932
0.0ProMet: 0.0 ± 0.0
2.247ProAsn: 2.247 ± 1.406
2.247ProPro: 2.247 ± 0.114
2.247ProGln: 2.247 ± 1.406
4.494ProArg: 4.494 ± 0.229
3.371ProSer: 3.371 ± 0.932
5.618ProThr: 5.618 ± 4.086
2.247ProVal: 2.247 ± 0.114
0.0ProTrp: 0.0 ± 0.0
1.124ProTyr: 1.124 ± 0.817
0.0ProXaa: 0.0 ± 0.0
Gln
5.618GlnAla: 5.618 ± 0.474
1.124GlnCys: 1.124 ± 0.703
5.618GlnAsp: 5.618 ± 1.046
0.0GlnGlu: 0.0 ± 0.0
3.371GlnPhe: 3.371 ± 0.588
1.124GlnGly: 1.124 ± 0.703
2.247GlnHis: 2.247 ± 1.634
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
4.494GlnLeu: 4.494 ± 1.291
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.124GlnPro: 1.124 ± 0.817
2.247GlnGln: 2.247 ± 0.114
2.247GlnArg: 2.247 ± 1.634
1.124GlnSer: 1.124 ± 0.703
1.124GlnThr: 1.124 ± 0.703
3.371GlnVal: 3.371 ± 0.588
0.0GlnTrp: 0.0 ± 0.0
2.247GlnTyr: 2.247 ± 1.406
0.0GlnXaa: 0.0 ± 0.0
Arg
3.371ArgAla: 3.371 ± 2.108
0.0ArgCys: 0.0 ± 0.0
3.371ArgAsp: 3.371 ± 0.932
4.494ArgGlu: 4.494 ± 1.749
2.247ArgPhe: 2.247 ± 0.114
1.124ArgGly: 1.124 ± 0.703
1.124ArgHis: 1.124 ± 0.703
5.618ArgIle: 5.618 ± 1.994
3.371ArgLys: 3.371 ± 0.932
4.494ArgLeu: 4.494 ± 1.291
1.124ArgMet: 1.124 ± 0.817
1.124ArgAsn: 1.124 ± 0.817
2.247ArgPro: 2.247 ± 1.634
4.494ArgGln: 4.494 ± 1.291
6.742ArgArg: 6.742 ± 3.383
5.618ArgSer: 5.618 ± 2.566
6.742ArgThr: 6.742 ± 0.343
4.494ArgVal: 4.494 ± 1.749
0.0ArgTrp: 0.0 ± 0.0
4.494ArgTyr: 4.494 ± 1.749
0.0ArgXaa: 0.0 ± 0.0
Ser
7.865SerAla: 7.865 ± 0.359
0.0SerCys: 0.0 ± 0.0
2.247SerAsp: 2.247 ± 0.114
3.371SerGlu: 3.371 ± 0.588
0.0SerPhe: 0.0 ± 0.0
2.247SerGly: 2.247 ± 1.406
2.247SerHis: 2.247 ± 1.406
6.742SerIle: 6.742 ± 0.343
0.0SerLys: 0.0 ± 0.0
10.112SerLeu: 10.112 ± 1.765
2.247SerMet: 2.247 ± 0.114
1.124SerAsn: 1.124 ± 0.817
1.124SerPro: 1.124 ± 0.817
4.494SerGln: 4.494 ± 1.291
5.618SerArg: 5.618 ± 0.474
6.742SerSer: 6.742 ± 1.177
8.989SerThr: 8.989 ± 3.498
3.371SerVal: 3.371 ± 0.588
0.0SerTrp: 0.0 ± 0.0
7.865SerTyr: 7.865 ± 0.359
0.0SerXaa: 0.0 ± 0.0
Thr
6.742ThrAla: 6.742 ± 3.383
0.0ThrCys: 0.0 ± 0.0
2.247ThrAsp: 2.247 ± 0.114
7.865ThrGlu: 7.865 ± 2.68
6.742ThrPhe: 6.742 ± 0.343
5.618ThrGly: 5.618 ± 1.046
2.247ThrHis: 2.247 ± 0.114
1.124ThrIle: 1.124 ± 0.817
3.371ThrLys: 3.371 ± 0.588
5.618ThrLeu: 5.618 ± 1.046
0.0ThrMet: 0.0 ± 0.0
3.371ThrAsn: 3.371 ± 2.452
4.494ThrPro: 4.494 ± 3.269
4.494ThrGln: 4.494 ± 1.291
5.618ThrArg: 5.618 ± 1.046
5.618ThrSer: 5.618 ± 1.046
5.618ThrThr: 5.618 ± 2.566
4.494ThrVal: 4.494 ± 1.291
1.124ThrTrp: 1.124 ± 0.817
2.247ThrTyr: 2.247 ± 1.406
0.0ThrXaa: 0.0 ± 0.0
Val
6.742ValAla: 6.742 ± 0.343
1.124ValCys: 1.124 ± 0.817
2.247ValAsp: 2.247 ± 1.406
1.124ValGlu: 1.124 ± 0.703
1.124ValPhe: 1.124 ± 0.703
5.618ValGly: 5.618 ± 3.514
1.124ValHis: 1.124 ± 0.703
3.371ValIle: 3.371 ± 0.932
2.247ValLys: 2.247 ± 1.406
5.618ValLeu: 5.618 ± 1.994
2.247ValMet: 2.247 ± 1.14
2.247ValAsn: 2.247 ± 0.114
10.112ValPro: 10.112 ± 3.285
2.247ValGln: 2.247 ± 1.634
4.494ValArg: 4.494 ± 0.229
1.124ValSer: 1.124 ± 0.703
2.247ValThr: 2.247 ± 1.634
2.247ValVal: 2.247 ± 0.114
1.124ValTrp: 1.124 ± 0.703
2.247ValTyr: 2.247 ± 0.114
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.124TrpAsp: 1.124 ± 0.817
0.0TrpGlu: 0.0 ± 0.0
1.124TrpPhe: 1.124 ± 0.817
1.124TrpGly: 1.124 ± 0.703
2.247TrpHis: 2.247 ± 0.114
2.247TrpIle: 2.247 ± 0.114
1.124TrpLys: 1.124 ± 0.817
2.247TrpLeu: 2.247 ± 1.634
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.124TrpGln: 1.124 ± 0.817
1.124TrpArg: 1.124 ± 0.703
3.371TrpSer: 3.371 ± 2.108
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.124TrpTyr: 1.124 ± 0.817
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.371TyrAla: 3.371 ± 0.932
1.124TyrCys: 1.124 ± 0.817
4.494TyrAsp: 4.494 ± 1.749
5.618TyrGlu: 5.618 ± 0.474
2.247TyrPhe: 2.247 ± 0.114
3.371TyrGly: 3.371 ± 0.932
1.124TyrHis: 1.124 ± 0.817
4.494TyrIle: 4.494 ± 0.229
0.0TyrLys: 0.0 ± 0.0
4.494TyrLeu: 4.494 ± 1.291
0.0TyrMet: 0.0 ± 0.0
1.124TyrAsn: 1.124 ± 0.703
4.494TyrPro: 4.494 ± 2.811
0.0TyrGln: 0.0 ± 0.0
3.371TyrArg: 3.371 ± 0.588
5.618TyrSer: 5.618 ± 0.474
4.494TyrThr: 4.494 ± 2.811
6.742TyrVal: 6.742 ± 2.697
1.124TyrTrp: 1.124 ± 0.817
4.494TyrTyr: 4.494 ± 0.229
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (891 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski