Amino acid dipepetide frequency for Grapevine Algerian latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.483AlaAla: 7.483 ± 2.144
0.534AlaCys: 0.534 ± 0.591
1.603AlaAsp: 1.603 ± 0.989
2.138AlaGlu: 2.138 ± 1.072
3.207AlaPhe: 3.207 ± 0.538
4.81AlaGly: 4.81 ± 1.619
3.207AlaHis: 3.207 ± 1.12
4.276AlaIle: 4.276 ± 0.91
5.345AlaLys: 5.345 ± 1.954
10.155AlaLeu: 10.155 ± 1.233
2.672AlaMet: 2.672 ± 1.192
3.741AlaAsn: 3.741 ± 2.639
4.276AlaPro: 4.276 ± 0.91
2.672AlaGln: 2.672 ± 0.404
5.345AlaArg: 5.345 ± 1.734
4.81AlaSer: 4.81 ± 1.05
7.483AlaThr: 7.483 ± 2.468
7.483AlaVal: 7.483 ± 2.406
0.534AlaTrp: 0.534 ± 0.349
0.534AlaTyr: 0.534 ± 0.569
0.0AlaXaa: 0.0 ± 0.0
Cys
3.207CysAla: 3.207 ± 0.958
1.069CysCys: 1.069 ± 0.563
1.603CysAsp: 1.603 ± 0.509
1.069CysGlu: 1.069 ± 0.659
1.603CysPhe: 1.603 ± 0.789
1.069CysGly: 1.069 ± 0.659
0.0CysHis: 0.0 ± 0.0
0.534CysIle: 0.534 ± 0.349
0.0CysLys: 0.0 ± 0.0
2.138CysLeu: 2.138 ± 0.792
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.069CysPro: 1.069 ± 0.659
1.069CysGln: 1.069 ± 0.545
1.603CysArg: 1.603 ± 0.729
0.534CysSer: 0.534 ± 0.349
1.603CysThr: 1.603 ± 1.648
2.672CysVal: 2.672 ± 1.301
0.0CysTrp: 0.0 ± 0.0
0.534CysTyr: 0.534 ± 0.591
0.0CysXaa: 0.0 ± 0.0
Asp
2.672AspAla: 2.672 ± 1.251
3.741AspCys: 3.741 ± 1.803
1.069AspAsp: 1.069 ± 0.476
2.672AspGlu: 2.672 ± 0.936
1.603AspPhe: 1.603 ± 0.634
4.81AspGly: 4.81 ± 1.699
0.534AspHis: 0.534 ± 0.723
2.672AspIle: 2.672 ± 0.852
2.672AspLys: 2.672 ± 0.509
4.81AspLeu: 4.81 ± 1.267
1.069AspMet: 1.069 ± 0.476
0.0AspAsn: 0.0 ± 0.0
0.534AspPro: 0.534 ± 0.349
1.603AspGln: 1.603 ± 0.632
4.81AspArg: 4.81 ± 1.336
4.81AspSer: 4.81 ± 0.699
2.672AspThr: 2.672 ± 1.034
4.81AspVal: 4.81 ± 1.05
0.0AspTrp: 0.0 ± 0.0
1.069AspTyr: 1.069 ± 0.563
0.0AspXaa: 0.0 ± 0.0
Glu
5.345GluAla: 5.345 ± 1.093
1.069GluCys: 1.069 ± 0.563
4.81GluAsp: 4.81 ± 1.703
2.672GluGlu: 2.672 ± 0.936
1.069GluPhe: 1.069 ± 0.699
2.138GluGly: 2.138 ± 0.853
0.534GluHis: 0.534 ± 0.349
2.138GluIle: 2.138 ± 1.126
3.207GluLys: 3.207 ± 1.17
6.414GluLeu: 6.414 ± 1.431
1.603GluMet: 1.603 ± 1.39
1.069GluAsn: 1.069 ± 0.563
2.138GluPro: 2.138 ± 0.505
2.138GluGln: 2.138 ± 1.326
4.81GluArg: 4.81 ± 2.043
6.414GluSer: 6.414 ± 3.267
2.672GluThr: 2.672 ± 0.704
3.741GluVal: 3.741 ± 1.382
2.138GluTrp: 2.138 ± 0.792
1.603GluTyr: 1.603 ± 0.632
0.0GluXaa: 0.0 ± 0.0
Phe
1.069PheAla: 1.069 ± 0.563
1.603PheCys: 1.603 ± 0.612
1.069PheAsp: 1.069 ± 0.699
1.069PheGlu: 1.069 ± 1.005
0.0PhePhe: 0.0 ± 0.0
5.345PheGly: 5.345 ± 0.908
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
3.207PheLys: 3.207 ± 1.989
4.276PheLeu: 4.276 ± 1.21
2.138PheMet: 2.138 ± 0.665
1.603PheAsn: 1.603 ± 0.509
0.0PhePro: 0.0 ± 0.0
2.138PheGln: 2.138 ± 0.995
2.138PheArg: 2.138 ± 0.62
2.138PheSer: 2.138 ± 1.072
0.534PheThr: 0.534 ± 0.349
3.741PheVal: 3.741 ± 0.953
0.534PheTrp: 0.534 ± 0.349
1.603PheTyr: 1.603 ± 0.612
0.0PheXaa: 0.0 ± 0.0
Gly
4.276GlyAla: 4.276 ± 2.43
3.207GlyCys: 3.207 ± 1.344
4.81GlyAsp: 4.81 ± 1.628
2.138GlyGlu: 2.138 ± 0.995
2.138GlyPhe: 2.138 ± 0.853
5.879GlyGly: 5.879 ± 1.794
0.0GlyHis: 0.0 ± 0.0
2.672GlyIle: 2.672 ± 1.445
6.948GlyLys: 6.948 ± 0.971
6.948GlyLeu: 6.948 ± 1.235
0.534GlyMet: 0.534 ± 0.591
3.741GlyAsn: 3.741 ± 0.616
1.069GlyPro: 1.069 ± 0.476
1.603GlyGln: 1.603 ± 1.277
4.81GlyArg: 4.81 ± 1.392
7.483GlySer: 7.483 ± 2.976
4.276GlyThr: 4.276 ± 2.104
7.483GlyVal: 7.483 ± 1.337
0.534GlyTrp: 0.534 ± 0.349
4.276GlyTyr: 4.276 ± 1.046
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
2.138HisCys: 2.138 ± 0.961
0.0HisAsp: 0.0 ± 0.0
0.534HisGlu: 0.534 ± 0.349
0.0HisPhe: 0.0 ± 0.0
1.069HisGly: 1.069 ± 0.699
0.534HisHis: 0.534 ± 0.349
0.534HisIle: 0.534 ± 0.349
0.534HisLys: 0.534 ± 0.349
2.138HisLeu: 2.138 ± 1.09
1.603HisMet: 1.603 ± 0.729
1.603HisAsn: 1.603 ± 0.768
1.069HisPro: 1.069 ± 0.659
0.534HisGln: 0.534 ± 0.349
1.603HisArg: 1.603 ± 0.669
1.069HisSer: 1.069 ± 0.476
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.741IleAla: 3.741 ± 1.425
1.069IleCys: 1.069 ± 0.563
1.069IleAsp: 1.069 ± 0.476
2.672IleGlu: 2.672 ± 1.165
3.741IlePhe: 3.741 ± 1.118
3.207IleGly: 3.207 ± 1.206
0.0IleHis: 0.0 ± 0.0
0.534IleIle: 0.534 ± 0.591
1.603IleLys: 1.603 ± 0.632
3.207IleLeu: 3.207 ± 0.805
1.069IleMet: 1.069 ± 0.563
2.138IleAsn: 2.138 ± 0.875
3.207IlePro: 3.207 ± 0.479
1.069IleGln: 1.069 ± 0.659
4.81IleArg: 4.81 ± 1.159
1.069IleSer: 1.069 ± 0.545
4.81IleThr: 4.81 ± 2.481
2.138IleVal: 2.138 ± 0.585
1.603IleTrp: 1.603 ± 0.634
1.069IleTyr: 1.069 ± 0.563
0.0IleXaa: 0.0 ± 0.0
Lys
4.81LysAla: 4.81 ± 1.324
0.534LysCys: 0.534 ± 0.723
4.276LysAsp: 4.276 ± 0.91
3.741LysGlu: 3.741 ± 1.221
1.603LysPhe: 1.603 ± 0.509
5.345LysGly: 5.345 ± 2.048
0.534LysHis: 0.534 ± 0.349
3.207LysIle: 3.207 ± 1.105
4.276LysLys: 4.276 ± 1.169
8.017LysLeu: 8.017 ± 1.607
1.069LysMet: 1.069 ± 0.525
2.138LysAsn: 2.138 ± 0.505
2.138LysPro: 2.138 ± 1.127
0.534LysGln: 0.534 ± 0.349
3.207LysArg: 3.207 ± 0.733
0.534LysSer: 0.534 ± 0.569
1.603LysThr: 1.603 ± 0.634
6.948LysVal: 6.948 ± 0.822
3.207LysTrp: 3.207 ± 1.077
0.0LysTyr: 0.0 ± 0.0
0.534LysXaa: 0.534 ± 0.349
Leu
12.293LeuAla: 12.293 ± 2.429
0.534LeuCys: 0.534 ± 0.569
2.672LeuAsp: 2.672 ± 1.204
4.276LeuGlu: 4.276 ± 1.389
1.603LeuPhe: 1.603 ± 0.632
10.155LeuGly: 10.155 ± 2.313
3.207LeuHis: 3.207 ± 1.309
2.672LeuIle: 2.672 ± 0.509
7.483LeuLys: 7.483 ± 1.288
9.621LeuLeu: 9.621 ± 2.519
1.603LeuMet: 1.603 ± 0.612
1.603LeuAsn: 1.603 ± 0.989
7.483LeuPro: 7.483 ± 0.754
2.672LeuGln: 2.672 ± 1.51
5.345LeuArg: 5.345 ± 1.641
9.086LeuSer: 9.086 ± 0.947
5.345LeuThr: 5.345 ± 1.432
6.948LeuVal: 6.948 ± 1.579
1.069LeuTrp: 1.069 ± 0.563
2.138LeuTyr: 2.138 ± 1.326
0.0LeuXaa: 0.0 ± 0.0
Met
1.069MetAla: 1.069 ± 0.868
0.534MetCys: 0.534 ± 0.349
2.672MetAsp: 2.672 ± 0.404
4.276MetGlu: 4.276 ± 0.697
0.0MetPhe: 0.0 ± 0.0
1.069MetGly: 1.069 ± 1.137
0.0MetHis: 0.0 ± 0.0
2.672MetIle: 2.672 ± 1.043
2.138MetLys: 2.138 ± 0.995
1.069MetLeu: 1.069 ± 0.868
0.534MetMet: 0.534 ± 0.569
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.534MetGln: 0.534 ± 0.591
1.603MetArg: 1.603 ± 0.729
1.603MetSer: 1.603 ± 0.699
2.672MetThr: 2.672 ± 0.91
1.603MetVal: 1.603 ± 1.048
0.0MetTrp: 0.0 ± 0.0
2.138MetTyr: 2.138 ± 1.072
0.0MetXaa: 0.0 ± 0.0
Asn
1.603AsnAla: 1.603 ± 0.612
0.534AsnCys: 0.534 ± 0.349
1.069AsnAsp: 1.069 ± 0.868
2.138AsnGlu: 2.138 ± 0.665
0.534AsnPhe: 0.534 ± 0.591
2.138AsnGly: 2.138 ± 1.542
0.534AsnHis: 0.534 ± 0.349
2.138AsnIle: 2.138 ± 0.995
2.672AsnLys: 2.672 ± 1.034
2.672AsnLeu: 2.672 ± 1.039
0.0AsnMet: 0.0 ± 0.0
1.603AsnAsn: 1.603 ± 0.989
1.603AsnPro: 1.603 ± 0.989
1.069AsnGln: 1.069 ± 1.137
3.207AsnArg: 3.207 ± 0.958
2.672AsnSer: 2.672 ± 1.316
1.603AsnThr: 1.603 ± 0.989
4.276AsnVal: 4.276 ± 1.862
0.0AsnTrp: 0.0 ± 0.0
0.534AsnTyr: 0.534 ± 0.349
0.0AsnXaa: 0.0 ± 0.0
Pro
2.672ProAla: 2.672 ± 0.404
0.534ProCys: 0.534 ± 0.723
2.138ProAsp: 2.138 ± 0.792
2.672ProGlu: 2.672 ± 0.936
1.069ProPhe: 1.069 ± 0.659
1.069ProGly: 1.069 ± 0.699
0.0ProHis: 0.0 ± 0.0
1.603ProIle: 1.603 ± 0.634
2.138ProLys: 2.138 ± 1.126
6.414ProLeu: 6.414 ± 1.414
0.534ProMet: 0.534 ± 0.553
0.534ProAsn: 0.534 ± 0.349
1.069ProPro: 1.069 ± 0.545
2.138ProGln: 2.138 ± 0.953
5.879ProArg: 5.879 ± 2.055
4.276ProSer: 4.276 ± 1.21
2.672ProThr: 2.672 ± 2.103
5.345ProVal: 5.345 ± 1.927
1.069ProTrp: 1.069 ± 0.819
1.603ProTyr: 1.603 ± 0.634
0.0ProXaa: 0.0 ± 0.0
Gln
2.672GlnAla: 2.672 ± 0.721
0.534GlnCys: 0.534 ± 0.591
0.534GlnAsp: 0.534 ± 0.591
2.138GlnGlu: 2.138 ± 0.665
1.603GlnPhe: 1.603 ± 1.082
1.069GlnGly: 1.069 ± 0.659
1.603GlnHis: 1.603 ± 0.699
1.603GlnIle: 1.603 ± 0.669
0.0GlnLys: 0.0 ± 0.0
4.276GlnLeu: 4.276 ± 0.636
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.603GlnPro: 1.603 ± 0.612
0.0GlnGln: 0.0 ± 0.0
3.741GlnArg: 3.741 ± 1.34
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
3.741GlnVal: 3.741 ± 1.244
0.534GlnTrp: 0.534 ± 0.569
2.138GlnTyr: 2.138 ± 1.542
0.0GlnXaa: 0.0 ± 0.0
Arg
6.948ArgAla: 6.948 ± 1.423
0.534ArgCys: 0.534 ± 0.723
3.207ArgAsp: 3.207 ± 1.12
5.879ArgGlu: 5.879 ± 1.231
4.276ArgPhe: 4.276 ± 1.24
5.345ArgGly: 5.345 ± 2.1
1.069ArgHis: 1.069 ± 0.699
2.672ArgIle: 2.672 ± 1.595
3.741ArgLys: 3.741 ± 1.527
6.414ArgLeu: 6.414 ± 1.184
2.672ArgMet: 2.672 ± 1.255
3.741ArgAsn: 3.741 ± 1.469
3.207ArgPro: 3.207 ± 1.688
1.603ArgGln: 1.603 ± 0.509
6.948ArgArg: 6.948 ± 1.698
1.069ArgSer: 1.069 ± 1.005
7.483ArgThr: 7.483 ± 2.626
6.414ArgVal: 6.414 ± 1.064
1.069ArgTrp: 1.069 ± 0.659
4.276ArgTyr: 4.276 ± 1.585
0.0ArgXaa: 0.0 ± 0.0
Ser
4.81SerAla: 4.81 ± 1.392
0.534SerCys: 0.534 ± 0.723
3.741SerAsp: 3.741 ± 1.685
2.672SerGlu: 2.672 ± 2.765
2.138SerPhe: 2.138 ± 0.995
4.81SerGly: 4.81 ± 1.506
0.534SerHis: 0.534 ± 0.349
3.207SerIle: 3.207 ± 0.733
2.672SerLys: 2.672 ± 1.034
6.414SerLeu: 6.414 ± 1.302
2.138SerMet: 2.138 ± 0.585
1.603SerAsn: 1.603 ± 0.632
3.207SerPro: 3.207 ± 0.552
2.138SerGln: 2.138 ± 0.505
5.345SerArg: 5.345 ± 1.685
2.138SerSer: 2.138 ± 1.454
3.207SerThr: 3.207 ± 0.733
5.345SerVal: 5.345 ± 1.628
1.603SerTrp: 1.603 ± 1.493
3.207SerTyr: 3.207 ± 0.805
0.0SerXaa: 0.0 ± 0.0
Thr
5.345ThrAla: 5.345 ± 2.144
0.534ThrCys: 0.534 ± 0.349
4.81ThrAsp: 4.81 ± 1.088
3.207ThrGlu: 3.207 ± 1.842
2.138ThrPhe: 2.138 ± 0.953
7.483ThrGly: 7.483 ± 1.81
0.534ThrHis: 0.534 ± 0.569
3.741ThrIle: 3.741 ± 1.223
4.81ThrLys: 4.81 ± 1.56
4.276ThrLeu: 4.276 ± 1.294
2.138ThrMet: 2.138 ± 0.87
1.069ThrAsn: 1.069 ± 0.476
3.741ThrPro: 3.741 ± 0.997
0.534ThrGln: 0.534 ± 0.349
3.741ThrArg: 3.741 ± 2.527
1.069ThrSer: 1.069 ± 0.476
4.81ThrThr: 4.81 ± 3.081
4.276ThrVal: 4.276 ± 2.853
0.0ThrTrp: 0.0 ± 0.0
2.138ThrTyr: 2.138 ± 0.62
0.0ThrXaa: 0.0 ± 0.0
Val
7.483ValAla: 7.483 ± 3.646
1.603ValCys: 1.603 ± 0.729
3.207ValAsp: 3.207 ± 0.958
8.552ValGlu: 8.552 ± 2.902
4.276ValPhe: 4.276 ± 0.51
5.879ValGly: 5.879 ± 1.403
2.138ValHis: 2.138 ± 1.397
5.345ValIle: 5.345 ± 1.441
2.672ValLys: 2.672 ± 1.255
3.207ValLeu: 3.207 ± 0.99
2.672ValMet: 2.672 ± 0.908
4.81ValAsn: 4.81 ± 1.498
5.345ValPro: 5.345 ± 1.292
1.069ValGln: 1.069 ± 0.699
7.483ValArg: 7.483 ± 1.74
7.483ValSer: 7.483 ± 3.708
4.81ValThr: 4.81 ± 2.968
6.948ValVal: 6.948 ± 1.708
0.0ValTrp: 0.0 ± 0.0
2.138ValTyr: 2.138 ± 1.126
0.0ValXaa: 0.0 ± 0.0
Trp
1.603TrpAla: 1.603 ± 0.632
0.534TrpCys: 0.534 ± 0.723
2.138TrpAsp: 2.138 ± 0.62
1.603TrpGlu: 1.603 ± 0.789
1.069TrpPhe: 1.069 ± 0.563
1.069TrpGly: 1.069 ± 0.563
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.069TrpLys: 1.069 ± 0.545
1.069TrpLeu: 1.069 ± 1.137
0.0TrpMet: 0.0 ± 0.0
0.534TrpAsn: 0.534 ± 0.591
1.069TrpPro: 1.069 ± 0.563
1.069TrpGln: 1.069 ± 0.545
1.069TrpArg: 1.069 ± 0.659
0.534TrpSer: 0.534 ± 0.349
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.741TyrAla: 3.741 ± 1.425
0.0TyrCys: 0.0 ± 0.0
2.138TyrAsp: 2.138 ± 0.62
1.603TyrGlu: 1.603 ± 0.864
0.534TyrPhe: 0.534 ± 0.349
0.534TyrGly: 0.534 ± 0.569
0.0TyrHis: 0.0 ± 0.0
1.603TyrIle: 1.603 ± 0.634
1.069TyrLys: 1.069 ± 0.819
4.276TyrLeu: 4.276 ± 0.854
1.603TyrMet: 1.603 ± 0.729
1.069TyrAsn: 1.069 ± 0.476
1.603TyrPro: 1.603 ± 0.729
1.603TyrGln: 1.603 ± 0.634
1.069TyrArg: 1.069 ± 0.699
2.672TyrSer: 2.672 ± 0.721
2.138TyrThr: 2.138 ± 0.953
3.207TyrVal: 3.207 ± 0.805
0.534TyrTrp: 0.534 ± 0.569
0.534TyrTyr: 0.534 ± 0.349
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.534XaaGly: 0.534 ± 0.349
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1872 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski