Amino acid dipepetide frequency for Dokdonella koreensis DS-123

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
22.583AlaAla: 22.583 ± 0.248
1.369AlaCys: 1.369 ± 0.036
8.467AlaAsp: 8.467 ± 0.094
7.183AlaGlu: 7.183 ± 0.098
4.472AlaPhe: 4.472 ± 0.06
13.812AlaGly: 13.812 ± 0.139
2.543AlaHis: 2.543 ± 0.052
6.011AlaIle: 6.011 ± 0.071
2.454AlaLys: 2.454 ± 0.056
16.508AlaLeu: 16.508 ± 0.167
2.617AlaMet: 2.617 ± 0.044
2.788AlaAsn: 2.788 ± 0.06
7.709AlaPro: 7.709 ± 0.113
4.857AlaGln: 4.857 ± 0.071
11.241AlaArg: 11.241 ± 0.136
6.727AlaSer: 6.727 ± 0.093
7.233AlaThr: 7.233 ± 0.108
10.07AlaVal: 10.07 ± 0.112
2.244AlaTrp: 2.244 ± 0.045
2.655AlaTyr: 2.655 ± 0.053
0.0AlaXaa: 0.0 ± 0.0
Cys
1.217CysAla: 1.217 ± 0.034
0.102CysCys: 0.102 ± 0.009
0.443CysAsp: 0.443 ± 0.02
0.392CysGlu: 0.392 ± 0.015
0.238CysPhe: 0.238 ± 0.014
0.926CysGly: 0.926 ± 0.032
0.224CysHis: 0.224 ± 0.016
0.337CysIle: 0.337 ± 0.017
0.121CysLys: 0.121 ± 0.011
0.867CysLeu: 0.867 ± 0.025
0.129CysMet: 0.129 ± 0.01
0.213CysAsn: 0.213 ± 0.013
0.484CysPro: 0.484 ± 0.024
0.211CysGln: 0.211 ± 0.013
0.698CysArg: 0.698 ± 0.024
0.442CysSer: 0.442 ± 0.021
0.548CysThr: 0.548 ± 0.025
0.639CysVal: 0.639 ± 0.025
0.118CysTrp: 0.118 ± 0.011
0.199CysTyr: 0.199 ± 0.011
0.0CysXaa: 0.0 ± 0.0
Asp
8.927AspAla: 8.927 ± 0.1
0.519AspCys: 0.519 ± 0.02
3.167AspAsp: 3.167 ± 0.049
2.926AspGlu: 2.926 ± 0.049
2.082AspPhe: 2.082 ± 0.041
6.607AspGly: 6.607 ± 0.104
1.128AspHis: 1.128 ± 0.04
2.16AspIle: 2.16 ± 0.046
0.996AspLys: 0.996 ± 0.033
6.23AspLeu: 6.23 ± 0.07
0.895AspMet: 0.895 ± 0.023
1.13AspAsn: 1.13 ± 0.034
4.141AspPro: 4.141 ± 0.065
1.731AspGln: 1.731 ± 0.033
4.842AspArg: 4.842 ± 0.065
2.17AspSer: 2.17 ± 0.042
2.912AspThr: 2.912 ± 0.056
4.092AspVal: 4.092 ± 0.055
1.003AspTrp: 1.003 ± 0.029
1.562AspTyr: 1.562 ± 0.038
0.0AspXaa: 0.0 ± 0.0
Glu
7.177GluAla: 7.177 ± 0.104
0.325GluCys: 0.325 ± 0.015
2.434GluAsp: 2.434 ± 0.041
2.137GluGlu: 2.137 ± 0.049
1.389GluPhe: 1.389 ± 0.031
3.563GluGly: 3.563 ± 0.055
1.193GluHis: 1.193 ± 0.037
2.183GluIle: 2.183 ± 0.046
1.205GluLys: 1.205 ± 0.042
5.328GluLeu: 5.328 ± 0.078
0.77GluMet: 0.77 ± 0.025
1.142GluAsn: 1.142 ± 0.032
2.66GluPro: 2.66 ± 0.046
2.199GluGln: 2.199 ± 0.048
5.479GluArg: 5.479 ± 0.105
2.182GluSer: 2.182 ± 0.045
2.691GluThr: 2.691 ± 0.052
3.464GluVal: 3.464 ± 0.054
0.582GluTrp: 0.582 ± 0.019
0.95GluTyr: 0.95 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
4.561PheAla: 4.561 ± 0.073
0.275PheCys: 0.275 ± 0.015
2.654PheAsp: 2.654 ± 0.054
1.953PheGlu: 1.953 ± 0.047
1.092PhePhe: 1.092 ± 0.034
3.375PheGly: 3.375 ± 0.06
0.724PheHis: 0.724 ± 0.024
1.045PheIle: 1.045 ± 0.029
0.623PheLys: 0.623 ± 0.021
2.772PheLeu: 2.772 ± 0.057
0.507PheMet: 0.507 ± 0.019
0.908PheAsn: 0.908 ± 0.027
1.44PhePro: 1.44 ± 0.034
0.862PheGln: 0.862 ± 0.027
2.254PheArg: 2.254 ± 0.042
1.834PheSer: 1.834 ± 0.037
1.84PheThr: 1.84 ± 0.044
2.654PheVal: 2.654 ± 0.046
0.466PheTrp: 0.466 ± 0.022
0.787PheTyr: 0.787 ± 0.028
0.0PheXaa: 0.0 ± 0.0
Gly
10.552GlyAla: 10.552 ± 0.104
0.899GlyCys: 0.899 ± 0.028
5.219GlyAsp: 5.219 ± 0.062
4.724GlyGlu: 4.724 ± 0.065
3.371GlyPhe: 3.371 ± 0.056
8.347GlyGly: 8.347 ± 0.13
1.954GlyHis: 1.954 ± 0.043
3.999GlyIle: 3.999 ± 0.058
2.278GlyLys: 2.278 ± 0.055
9.074GlyLeu: 9.074 ± 0.077
1.763GlyMet: 1.763 ± 0.036
2.385GlyAsn: 2.385 ± 0.054
3.861GlyPro: 3.861 ± 0.061
3.172GlyGln: 3.172 ± 0.061
7.549GlyArg: 7.549 ± 0.093
5.327GlySer: 5.327 ± 0.084
5.455GlyThr: 5.455 ± 0.095
6.25GlyVal: 6.25 ± 0.086
1.668GlyTrp: 1.668 ± 0.037
2.464GlyTyr: 2.464 ± 0.048
0.0GlyXaa: 0.0 ± 0.0
His
3.107HisAla: 3.107 ± 0.052
0.213HisCys: 0.213 ± 0.012
1.147HisAsp: 1.147 ± 0.031
1.023HisGlu: 1.023 ± 0.03
0.724HisPhe: 0.724 ± 0.024
2.188HisGly: 2.188 ± 0.046
0.503HisHis: 0.503 ± 0.022
0.597HisIle: 0.597 ± 0.024
0.302HisLys: 0.302 ± 0.015
2.261HisLeu: 2.261 ± 0.049
0.33HisMet: 0.33 ± 0.017
0.402HisAsn: 0.402 ± 0.019
1.419HisPro: 1.419 ± 0.039
0.541HisGln: 0.541 ± 0.019
1.808HisArg: 1.808 ± 0.043
0.813HisSer: 0.813 ± 0.027
0.844HisThr: 0.844 ± 0.025
1.514HisVal: 1.514 ± 0.036
0.429HisTrp: 0.429 ± 0.018
0.547HisTyr: 0.547 ± 0.02
0.0HisXaa: 0.0 ± 0.0
Ile
6.713IleAla: 6.713 ± 0.078
0.299IleCys: 0.299 ± 0.016
3.597IleAsp: 3.597 ± 0.057
2.933IleGlu: 2.933 ± 0.053
1.028IlePhe: 1.028 ± 0.03
4.622IleGly: 4.622 ± 0.063
0.774IleHis: 0.774 ± 0.026
1.034IleIle: 1.034 ± 0.033
0.889IleLys: 0.889 ± 0.032
2.998IleLeu: 2.998 ± 0.054
0.443IleMet: 0.443 ± 0.02
1.044IleAsn: 1.044 ± 0.032
1.924IlePro: 1.924 ± 0.044
1.025IleGln: 1.025 ± 0.031
2.815IleArg: 2.815 ± 0.042
1.74IleSer: 1.74 ± 0.041
2.025IleThr: 2.025 ± 0.052
3.655IleVal: 3.655 ± 0.054
0.406IleTrp: 0.406 ± 0.018
0.821IleTyr: 0.821 ± 0.029
0.0IleXaa: 0.0 ± 0.0
Lys
2.695LysAla: 2.695 ± 0.06
0.095LysCys: 0.095 ± 0.011
1.125LysAsp: 1.125 ± 0.034
0.898LysGlu: 0.898 ± 0.029
0.492LysPhe: 0.492 ± 0.02
1.425LysGly: 1.425 ± 0.037
0.399LysHis: 0.399 ± 0.019
0.892LysIle: 0.892 ± 0.032
0.714LysLys: 0.714 ± 0.033
2.184LysLeu: 2.184 ± 0.048
0.349LysMet: 0.349 ± 0.017
0.541LysAsn: 0.541 ± 0.023
1.455LysPro: 1.455 ± 0.043
0.723LysGln: 0.723 ± 0.027
1.669LysArg: 1.669 ± 0.041
0.961LysSer: 0.961 ± 0.028
1.29LysThr: 1.29 ± 0.04
1.506LysVal: 1.506 ± 0.04
0.201LysTrp: 0.201 ± 0.013
0.395LysTyr: 0.395 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
17.835LeuAla: 17.835 ± 0.189
0.88LeuCys: 0.88 ± 0.025
7.005LeuAsp: 7.005 ± 0.093
4.736LeuGlu: 4.736 ± 0.079
3.296LeuPhe: 3.296 ± 0.057
8.92LeuGly: 8.92 ± 0.087
2.149LeuHis: 2.149 ± 0.041
4.086LeuIle: 4.086 ± 0.055
2.386LeuLys: 2.386 ± 0.047
11.632LeuLeu: 11.632 ± 0.141
1.686LeuMet: 1.686 ± 0.04
2.028LeuAsn: 2.028 ± 0.031
6.68LeuPro: 6.68 ± 0.085
3.169LeuGln: 3.169 ± 0.052
9.303LeuArg: 9.303 ± 0.111
5.162LeuSer: 5.162 ± 0.072
5.321LeuThr: 5.321 ± 0.072
8.236LeuVal: 8.236 ± 0.102
1.392LeuTrp: 1.392 ± 0.038
2.207LeuTyr: 2.207 ± 0.046
0.0LeuXaa: 0.0 ± 0.0
Met
2.145MetAla: 2.145 ± 0.036
0.101MetCys: 0.101 ± 0.007
0.843MetAsp: 0.843 ± 0.03
0.626MetGlu: 0.626 ± 0.022
0.47MetPhe: 0.47 ± 0.02
1.057MetGly: 1.057 ± 0.036
0.393MetHis: 0.393 ± 0.018
0.763MetIle: 0.763 ± 0.025
0.558MetLys: 0.558 ± 0.019
1.909MetLeu: 1.909 ± 0.043
0.3MetMet: 0.3 ± 0.016
0.632MetAsn: 0.632 ± 0.022
1.137MetPro: 1.137 ± 0.033
0.659MetGln: 0.659 ± 0.025
1.523MetArg: 1.523 ± 0.037
1.164MetSer: 1.164 ± 0.027
1.292MetThr: 1.292 ± 0.033
1.094MetVal: 1.094 ± 0.028
0.13MetTrp: 0.13 ± 0.01
0.269MetTyr: 0.269 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
2.97AsnAla: 2.97 ± 0.051
0.206AsnCys: 0.206 ± 0.014
1.224AsnAsp: 1.224 ± 0.03
1.01AsnGlu: 1.01 ± 0.028
0.692AsnPhe: 0.692 ± 0.025
2.502AsnGly: 2.502 ± 0.059
0.447AsnHis: 0.447 ± 0.019
0.876AsnIle: 0.876 ± 0.027
0.408AsnLys: 0.408 ± 0.018
2.478AsnLeu: 2.478 ± 0.048
0.312AsnMet: 0.312 ± 0.016
0.619AsnAsn: 0.619 ± 0.03
1.575AsnPro: 1.575 ± 0.042
0.697AsnGln: 0.697 ± 0.021
1.81AsnArg: 1.81 ± 0.037
0.982AsnSer: 0.982 ± 0.032
1.212AsnThr: 1.212 ± 0.041
1.702AsnVal: 1.702 ± 0.041
0.341AsnTrp: 0.341 ± 0.016
0.611AsnTyr: 0.611 ± 0.025
0.0AsnXaa: 0.0 ± 0.0
Pro
9.75ProAla: 9.75 ± 0.119
0.406ProCys: 0.406 ± 0.025
3.933ProAsp: 3.933 ± 0.066
2.974ProGlu: 2.974 ± 0.052
1.682ProPhe: 1.682 ± 0.035
5.438ProGly: 5.438 ± 0.081
1.019ProHis: 1.019 ± 0.029
1.994ProIle: 1.994 ± 0.037
1.037ProLys: 1.037 ± 0.031
5.702ProLeu: 5.702 ± 0.077
1.118ProMet: 1.118 ± 0.028
1.196ProAsn: 1.196 ± 0.033
3.715ProPro: 3.715 ± 0.073
1.893ProGln: 1.893 ± 0.042
3.681ProArg: 3.681 ± 0.06
2.822ProSer: 2.822 ± 0.054
2.593ProThr: 2.593 ± 0.053
4.721ProVal: 4.721 ± 0.064
0.845ProTrp: 0.845 ± 0.026
1.2ProTyr: 1.2 ± 0.031
0.0ProXaa: 0.0 ± 0.0
Gln
5.446GlnAla: 5.446 ± 0.077
0.225GlnCys: 0.225 ± 0.012
1.326GlnAsp: 1.326 ± 0.036
1.08GlnGlu: 1.08 ± 0.032
0.987GlnPhe: 0.987 ± 0.028
2.515GlnGly: 2.515 ± 0.044
0.672GlnHis: 0.672 ± 0.022
1.385GlnIle: 1.385 ± 0.037
0.621GlnLys: 0.621 ± 0.025
3.378GlnLeu: 3.378 ± 0.047
0.625GlnMet: 0.625 ± 0.024
0.653GlnAsn: 0.653 ± 0.025
2.251GlnPro: 2.251 ± 0.052
1.326GlnGln: 1.326 ± 0.037
3.342GlnArg: 3.342 ± 0.056
1.423GlnSer: 1.423 ± 0.037
1.664GlnThr: 1.664 ± 0.034
2.884GlnVal: 2.884 ± 0.046
0.495GlnTrp: 0.495 ± 0.021
0.629GlnTyr: 0.629 ± 0.024
0.0GlnXaa: 0.0 ± 0.0
Arg
9.559ArgAla: 9.559 ± 0.113
0.713ArgCys: 0.713 ± 0.026
4.49ArgAsp: 4.49 ± 0.065
4.524ArgGlu: 4.524 ± 0.068
3.149ArgPhe: 3.149 ± 0.053
5.585ArgGly: 5.585 ± 0.074
2.071ArgHis: 2.071 ± 0.046
4.347ArgIle: 4.347 ± 0.061
1.544ArgLys: 1.544 ± 0.042
10.055ArgLeu: 10.055 ± 0.122
1.707ArgMet: 1.707 ± 0.034
1.826ArgAsn: 1.826 ± 0.039
4.41ArgPro: 4.41 ± 0.065
2.983ArgGln: 2.983 ± 0.048
7.558ArgArg: 7.558 ± 0.102
4.159ArgSer: 4.159 ± 0.067
3.892ArgThr: 3.892 ± 0.055
5.695ArgVal: 5.695 ± 0.07
1.517ArgTrp: 1.517 ± 0.035
2.399ArgTyr: 2.399 ± 0.049
0.0ArgXaa: 0.0 ± 0.0
Ser
6.296SerAla: 6.296 ± 0.085
0.439SerCys: 0.439 ± 0.022
2.655SerAsp: 2.655 ± 0.046
2.23SerGlu: 2.23 ± 0.047
1.746SerPhe: 1.746 ± 0.038
5.538SerGly: 5.538 ± 0.08
0.996SerHis: 0.996 ± 0.025
2.1SerIle: 2.1 ± 0.046
0.903SerLys: 0.903 ± 0.029
5.001SerLeu: 5.001 ± 0.07
0.873SerMet: 0.873 ± 0.028
1.252SerAsn: 1.252 ± 0.033
2.83SerPro: 2.83 ± 0.048
1.44SerGln: 1.44 ± 0.03
3.563SerArg: 3.563 ± 0.05
2.506SerSer: 2.506 ± 0.059
2.723SerThr: 2.723 ± 0.064
3.527SerVal: 3.527 ± 0.061
0.732SerTrp: 0.732 ± 0.025
1.233SerTyr: 1.233 ± 0.041
0.0SerXaa: 0.0 ± 0.0
Thr
7.023ThrAla: 7.023 ± 0.098
0.492ThrCys: 0.492 ± 0.028
2.828ThrAsp: 2.828 ± 0.067
1.993ThrGlu: 1.993 ± 0.042
1.714ThrPhe: 1.714 ± 0.048
5.332ThrGly: 5.332 ± 0.078
1.055ThrHis: 1.055 ± 0.029
2.577ThrIle: 2.577 ± 0.054
0.764ThrLys: 0.764 ± 0.027
6.415ThrLeu: 6.415 ± 0.095
0.821ThrMet: 0.821 ± 0.025
1.087ThrAsn: 1.087 ± 0.043
3.633ThrPro: 3.633 ± 0.065
1.584ThrGln: 1.584 ± 0.038
3.697ThrArg: 3.697 ± 0.056
2.353ThrSer: 2.353 ± 0.062
3.051ThrThr: 3.051 ± 0.082
4.552ThrVal: 4.552 ± 0.094
0.796ThrTrp: 0.796 ± 0.025
1.286ThrTyr: 1.286 ± 0.059
0.0ThrXaa: 0.0 ± 0.0
Val
10.578ValAla: 10.578 ± 0.104
0.646ValCys: 0.646 ± 0.025
4.572ValAsp: 4.572 ± 0.061
4.147ValGlu: 4.147 ± 0.061
2.609ValPhe: 2.609 ± 0.053
5.563ValGly: 5.563 ± 0.085
1.603ValHis: 1.603 ± 0.04
3.016ValIle: 3.016 ± 0.053
1.468ValLys: 1.468 ± 0.041
8.637ValLeu: 8.637 ± 0.094
1.222ValMet: 1.222 ± 0.028
1.806ValAsn: 1.806 ± 0.043
4.407ValPro: 4.407 ± 0.065
2.332ValGln: 2.332 ± 0.042
5.655ValArg: 5.655 ± 0.067
3.886ValSer: 3.886 ± 0.064
4.193ValThr: 4.193 ± 0.1
6.323ValVal: 6.323 ± 0.091
0.942ValTrp: 0.942 ± 0.029
1.605ValTyr: 1.605 ± 0.034
0.0ValXaa: 0.0 ± 0.0
Trp
1.283TrpAla: 1.283 ± 0.033
0.144TrpCys: 0.144 ± 0.011
0.657TrpAsp: 0.657 ± 0.022
0.495TrpGlu: 0.495 ± 0.019
0.559TrpPhe: 0.559 ± 0.023
0.889TrpGly: 0.889 ± 0.03
0.389TrpHis: 0.389 ± 0.019
0.772TrpIle: 0.772 ± 0.024
0.348TrpLys: 0.348 ± 0.016
2.232TrpLeu: 2.232 ± 0.051
0.311TrpMet: 0.311 ± 0.014
0.482TrpAsn: 0.482 ± 0.022
0.806TrpPro: 0.806 ± 0.03
0.752TrpGln: 0.752 ± 0.023
1.507TrpArg: 1.507 ± 0.035
0.904TrpSer: 0.904 ± 0.026
0.951TrpThr: 0.951 ± 0.03
0.916TrpVal: 0.916 ± 0.025
0.259TrpTrp: 0.259 ± 0.015
0.299TrpTyr: 0.299 ± 0.015
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.125TyrAla: 3.125 ± 0.058
0.204TyrCys: 0.204 ± 0.012
1.433TyrAsp: 1.433 ± 0.046
1.069TyrGlu: 1.069 ± 0.032
0.833TyrPhe: 0.833 ± 0.025
2.108TyrGly: 2.108 ± 0.043
0.476TyrHis: 0.476 ± 0.021
0.61TyrIle: 0.61 ± 0.024
0.389TyrLys: 0.389 ± 0.018
2.445TyrLeu: 2.445 ± 0.048
0.289TyrMet: 0.289 ± 0.019
0.538TyrAsn: 0.538 ± 0.021
1.185TyrPro: 1.185 ± 0.034
0.773TyrGln: 0.773 ± 0.026
2.187TyrArg: 2.187 ± 0.046
1.025TyrSer: 1.025 ± 0.032
1.323TyrThr: 1.323 ± 0.043
1.716TyrVal: 1.716 ± 0.039
0.39TyrTrp: 0.39 ± 0.018
0.592TyrTyr: 0.592 ± 0.025
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3774 proteins (1322314 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski