Amino acid dipepetide frequency for Simian mastadenovirus C

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.057AlaAla: 8.057 ± 1.493
1.139AlaCys: 1.139 ± 0.352
3.416AlaAsp: 3.416 ± 0.46
3.941AlaGlu: 3.941 ± 0.6
2.978AlaPhe: 2.978 ± 0.48
4.291AlaGly: 4.291 ± 0.789
1.314AlaHis: 1.314 ± 0.3
2.978AlaIle: 2.978 ± 0.545
1.839AlaLys: 1.839 ± 0.503
8.758AlaLeu: 8.758 ± 1.231
1.752AlaMet: 1.752 ± 0.375
3.24AlaAsn: 3.24 ± 0.648
5.08AlaPro: 5.08 ± 0.65
2.277AlaGln: 2.277 ± 0.446
5.342AlaArg: 5.342 ± 1.06
5.255AlaSer: 5.255 ± 0.817
4.467AlaThr: 4.467 ± 0.717
6.393AlaVal: 6.393 ± 0.716
1.051AlaTrp: 1.051 ± 0.23
2.803AlaTyr: 2.803 ± 0.466
0.0AlaXaa: 0.0 ± 0.0
Cys
1.752CysAla: 1.752 ± 0.418
1.314CysCys: 1.314 ± 0.33
1.226CysAsp: 1.226 ± 0.291
0.876CysGlu: 0.876 ± 0.258
0.963CysPhe: 0.963 ± 0.338
1.314CysGly: 1.314 ± 0.374
0.525CysHis: 0.525 ± 0.276
0.701CysIle: 0.701 ± 0.29
0.613CysLys: 0.613 ± 0.289
2.102CysLeu: 2.102 ± 0.489
0.438CysMet: 0.438 ± 0.211
0.788CysAsn: 0.788 ± 0.286
0.876CysPro: 0.876 ± 0.252
0.438CysGln: 0.438 ± 0.154
1.051CysArg: 1.051 ± 0.348
1.314CysSer: 1.314 ± 0.469
0.963CysThr: 0.963 ± 0.329
1.051CysVal: 1.051 ± 0.39
0.525CysTrp: 0.525 ± 0.248
1.051CysTyr: 1.051 ± 0.279
0.0CysXaa: 0.0 ± 0.0
Asp
3.065AspAla: 3.065 ± 0.507
0.963AspCys: 0.963 ± 0.306
2.54AspAsp: 2.54 ± 0.611
3.766AspGlu: 3.766 ± 0.628
2.014AspPhe: 2.014 ± 0.366
3.065AspGly: 3.065 ± 0.462
0.788AspHis: 0.788 ± 0.308
2.54AspIle: 2.54 ± 0.635
1.576AspLys: 1.576 ± 0.324
5.167AspLeu: 5.167 ± 0.757
1.226AspMet: 1.226 ± 0.275
1.752AspAsn: 1.752 ± 0.47
2.715AspPro: 2.715 ± 0.448
0.788AspGln: 0.788 ± 0.22
3.678AspArg: 3.678 ± 0.692
3.766AspSer: 3.766 ± 0.61
2.277AspThr: 2.277 ± 0.727
3.416AspVal: 3.416 ± 0.562
0.438AspTrp: 0.438 ± 0.148
2.19AspTyr: 2.19 ± 0.522
0.0AspXaa: 0.0 ± 0.0
Glu
4.992GluAla: 4.992 ± 0.935
1.051GluCys: 1.051 ± 0.385
3.503GluAsp: 3.503 ± 0.536
7.269GluGlu: 7.269 ± 1.531
1.664GluPhe: 1.664 ± 0.335
4.467GluGly: 4.467 ± 0.69
1.226GluHis: 1.226 ± 0.397
2.627GluIle: 2.627 ± 0.538
2.803GluLys: 2.803 ± 0.481
5.518GluLeu: 5.518 ± 0.742
1.752GluMet: 1.752 ± 0.403
3.416GluAsn: 3.416 ± 0.592
2.627GluPro: 2.627 ± 0.383
2.102GluGln: 2.102 ± 0.381
4.029GluArg: 4.029 ± 0.846
2.715GluSer: 2.715 ± 0.476
3.416GluThr: 3.416 ± 0.508
3.766GluVal: 3.766 ± 0.605
0.701GluTrp: 0.701 ± 0.252
1.139GluTyr: 1.139 ± 0.366
0.0GluXaa: 0.0 ± 0.0
Phe
2.803PheAla: 2.803 ± 0.474
0.788PheCys: 0.788 ± 0.223
2.102PheAsp: 2.102 ± 0.506
1.839PheGlu: 1.839 ± 0.383
1.752PhePhe: 1.752 ± 0.442
0.788PheGly: 0.788 ± 0.223
0.963PheHis: 0.963 ± 0.312
1.664PheIle: 1.664 ± 0.41
1.226PheLys: 1.226 ± 0.358
3.153PheLeu: 3.153 ± 0.479
1.051PheMet: 1.051 ± 0.278
2.627PheAsn: 2.627 ± 0.646
1.752PhePro: 1.752 ± 0.331
2.54PheGln: 2.54 ± 0.421
2.89PheArg: 2.89 ± 0.48
3.328PheSer: 3.328 ± 0.423
2.715PheThr: 2.715 ± 0.439
3.416PheVal: 3.416 ± 0.579
0.263PheTrp: 0.263 ± 0.134
2.014PheTyr: 2.014 ± 0.328
0.0PheXaa: 0.0 ± 0.0
Gly
5.43GlyAla: 5.43 ± 0.835
0.876GlyCys: 0.876 ± 0.331
2.277GlyAsp: 2.277 ± 0.365
3.591GlyGlu: 3.591 ± 0.43
2.014GlyPhe: 2.014 ± 0.473
4.905GlyGly: 4.905 ± 0.759
1.314GlyHis: 1.314 ± 0.414
2.277GlyIle: 2.277 ± 0.52
1.752GlyLys: 1.752 ± 0.448
5.518GlyLeu: 5.518 ± 0.836
0.963GlyMet: 0.963 ± 0.31
2.627GlyAsn: 2.627 ± 0.816
2.452GlyPro: 2.452 ± 0.444
2.54GlyGln: 2.54 ± 0.644
5.167GlyArg: 5.167 ± 0.839
4.467GlySer: 4.467 ± 0.644
3.503GlyThr: 3.503 ± 0.498
5.78GlyVal: 5.78 ± 0.751
0.788GlyTrp: 0.788 ± 0.208
1.664GlyTyr: 1.664 ± 0.48
0.0GlyXaa: 0.0 ± 0.0
His
1.226HisAla: 1.226 ± 0.279
1.139HisCys: 1.139 ± 0.394
0.876HisAsp: 0.876 ± 0.39
0.876HisGlu: 0.876 ± 0.264
0.876HisPhe: 0.876 ± 0.309
1.664HisGly: 1.664 ± 0.516
0.701HisHis: 0.701 ± 0.295
0.876HisIle: 0.876 ± 0.237
0.613HisLys: 0.613 ± 0.288
2.803HisLeu: 2.803 ± 0.513
0.263HisMet: 0.263 ± 0.145
0.876HisAsn: 0.876 ± 0.275
1.664HisPro: 1.664 ± 0.549
0.701HisGln: 0.701 ± 0.249
1.927HisArg: 1.927 ± 0.336
1.139HisSer: 1.139 ± 0.331
0.788HisThr: 0.788 ± 0.216
1.489HisVal: 1.489 ± 0.351
0.438HisTrp: 0.438 ± 0.203
0.613HisTyr: 0.613 ± 0.194
0.0HisXaa: 0.0 ± 0.0
Ile
3.153IleAla: 3.153 ± 0.517
1.051IleCys: 1.051 ± 0.369
1.226IleAsp: 1.226 ± 0.323
2.19IleGlu: 2.19 ± 0.321
1.401IlePhe: 1.401 ± 0.463
2.715IleGly: 2.715 ± 0.524
0.525IleHis: 0.525 ± 0.206
1.664IleIle: 1.664 ± 0.516
1.927IleLys: 1.927 ± 0.429
2.89IleLeu: 2.89 ± 0.612
1.139IleMet: 1.139 ± 0.273
2.19IleAsn: 2.19 ± 0.415
2.452IlePro: 2.452 ± 0.508
1.752IleGln: 1.752 ± 0.321
2.365IleArg: 2.365 ± 0.557
3.153IleSer: 3.153 ± 0.417
2.715IleThr: 2.715 ± 0.644
2.365IleVal: 2.365 ± 0.487
0.263IleTrp: 0.263 ± 0.134
1.489IleTyr: 1.489 ± 0.423
0.0IleXaa: 0.0 ± 0.0
Lys
2.627LysAla: 2.627 ± 0.502
0.701LysCys: 0.701 ± 0.227
1.752LysAsp: 1.752 ± 0.413
2.452LysGlu: 2.452 ± 0.704
1.576LysPhe: 1.576 ± 0.349
2.54LysGly: 2.54 ± 0.438
0.788LysHis: 0.788 ± 0.23
2.014LysIle: 2.014 ± 0.397
2.19LysLys: 2.19 ± 0.549
2.978LysLeu: 2.978 ± 0.682
1.226LysMet: 1.226 ± 0.43
1.752LysAsn: 1.752 ± 0.286
2.803LysPro: 2.803 ± 0.517
1.314LysGln: 1.314 ± 0.359
3.24LysArg: 3.24 ± 0.836
2.277LysSer: 2.277 ± 0.556
1.839LysThr: 1.839 ± 0.34
2.54LysVal: 2.54 ± 0.434
0.438LysTrp: 0.438 ± 0.215
0.613LysTyr: 0.613 ± 0.19
0.0LysXaa: 0.0 ± 0.0
Leu
7.269LeuAla: 7.269 ± 0.782
2.102LeuCys: 2.102 ± 0.472
4.291LeuAsp: 4.291 ± 0.596
6.043LeuGlu: 6.043 ± 0.799
2.54LeuPhe: 2.54 ± 0.472
4.992LeuGly: 4.992 ± 0.833
3.591LeuHis: 3.591 ± 0.631
3.065LeuIle: 3.065 ± 0.472
5.08LeuLys: 5.08 ± 0.825
9.809LeuLeu: 9.809 ± 1.155
2.277LeuMet: 2.277 ± 0.396
5.167LeuAsn: 5.167 ± 0.717
6.306LeuPro: 6.306 ± 0.763
6.131LeuGln: 6.131 ± 0.991
7.006LeuArg: 7.006 ± 0.804
6.218LeuSer: 6.218 ± 0.748
6.569LeuThr: 6.569 ± 0.895
5.255LeuVal: 5.255 ± 0.683
1.226LeuTrp: 1.226 ± 0.269
3.766LeuTyr: 3.766 ± 0.686
0.0LeuXaa: 0.0 ± 0.0
Met
2.54MetAla: 2.54 ± 0.483
0.088MetCys: 0.088 ± 0.086
1.401MetAsp: 1.401 ± 0.321
2.102MetGlu: 2.102 ± 0.407
0.525MetPhe: 0.525 ± 0.182
1.401MetGly: 1.401 ± 0.305
0.788MetHis: 0.788 ± 0.368
0.788MetIle: 0.788 ± 0.326
0.876MetLys: 0.876 ± 0.259
2.102MetLeu: 2.102 ± 0.52
0.963MetMet: 0.963 ± 0.283
0.701MetAsn: 0.701 ± 0.281
1.752MetPro: 1.752 ± 0.38
1.489MetGln: 1.489 ± 0.382
1.576MetArg: 1.576 ± 0.373
1.226MetSer: 1.226 ± 0.268
1.139MetThr: 1.139 ± 0.3
1.051MetVal: 1.051 ± 0.375
0.35MetTrp: 0.35 ± 0.182
1.051MetTyr: 1.051 ± 0.291
0.0MetXaa: 0.0 ± 0.0
Asn
3.065AsnAla: 3.065 ± 0.652
1.051AsnCys: 1.051 ± 0.321
2.102AsnAsp: 2.102 ± 0.519
1.752AsnGlu: 1.752 ± 0.321
2.89AsnPhe: 2.89 ± 0.636
3.24AsnGly: 3.24 ± 0.758
0.701AsnHis: 0.701 ± 0.304
1.927AsnIle: 1.927 ± 0.351
1.401AsnLys: 1.401 ± 0.368
4.029AsnLeu: 4.029 ± 0.56
1.576AsnMet: 1.576 ± 0.442
2.715AsnAsn: 2.715 ± 0.85
4.291AsnPro: 4.291 ± 0.748
2.014AsnGln: 2.014 ± 0.404
2.452AsnArg: 2.452 ± 0.422
2.978AsnSer: 2.978 ± 0.575
2.627AsnThr: 2.627 ± 0.585
3.153AsnVal: 3.153 ± 0.471
0.613AsnTrp: 0.613 ± 0.221
2.277AsnTyr: 2.277 ± 0.506
0.0AsnXaa: 0.0 ± 0.0
Pro
3.941ProAla: 3.941 ± 0.665
1.226ProCys: 1.226 ± 0.411
3.503ProAsp: 3.503 ± 0.516
4.992ProGlu: 4.992 ± 0.864
2.803ProPhe: 2.803 ± 0.51
3.591ProGly: 3.591 ± 0.549
1.139ProHis: 1.139 ± 0.31
2.014ProIle: 2.014 ± 0.392
2.365ProLys: 2.365 ± 0.438
6.043ProLeu: 6.043 ± 1.011
1.401ProMet: 1.401 ± 0.407
2.365ProAsn: 2.365 ± 0.437
7.532ProPro: 7.532 ± 1.257
2.54ProGln: 2.54 ± 0.517
4.291ProArg: 4.291 ± 0.739
5.868ProSer: 5.868 ± 0.797
3.328ProThr: 3.328 ± 0.614
4.029ProVal: 4.029 ± 0.67
0.788ProTrp: 0.788 ± 0.28
2.365ProTyr: 2.365 ± 0.481
0.0ProXaa: 0.0 ± 0.0
Gln
3.503GlnAla: 3.503 ± 0.451
0.525GlnCys: 0.525 ± 0.197
1.664GlnAsp: 1.664 ± 0.379
2.54GlnGlu: 2.54 ± 0.456
1.401GlnPhe: 1.401 ± 0.234
2.277GlnGly: 2.277 ± 0.434
0.963GlnHis: 0.963 ± 0.229
1.489GlnIle: 1.489 ± 0.369
1.839GlnLys: 1.839 ± 0.465
4.116GlnLeu: 4.116 ± 0.552
1.226GlnMet: 1.226 ± 0.298
2.627GlnAsn: 2.627 ± 0.514
3.328GlnPro: 3.328 ± 0.381
2.365GlnGln: 2.365 ± 0.628
3.24GlnArg: 3.24 ± 0.485
3.24GlnSer: 3.24 ± 0.685
2.715GlnThr: 2.715 ± 0.583
2.19GlnVal: 2.19 ± 0.398
0.613GlnTrp: 0.613 ± 0.233
0.701GlnTyr: 0.701 ± 0.205
0.0GlnXaa: 0.0 ± 0.0
Arg
5.868ArgAla: 5.868 ± 1.017
1.664ArgCys: 1.664 ± 0.422
3.503ArgAsp: 3.503 ± 0.631
3.941ArgGlu: 3.941 ± 0.799
2.54ArgPhe: 2.54 ± 0.381
6.218ArgGly: 6.218 ± 0.749
1.576ArgHis: 1.576 ± 0.465
2.19ArgIle: 2.19 ± 0.378
3.065ArgLys: 3.065 ± 0.622
6.744ArgLeu: 6.744 ± 0.92
1.401ArgMet: 1.401 ± 0.265
2.978ArgAsn: 2.978 ± 0.496
4.204ArgPro: 4.204 ± 0.629
3.678ArgGln: 3.678 ± 0.539
9.108ArgArg: 9.108 ± 1.802
4.729ArgSer: 4.729 ± 0.755
3.328ArgThr: 3.328 ± 0.555
4.291ArgVal: 4.291 ± 0.697
1.314ArgTrp: 1.314 ± 0.293
2.102ArgTyr: 2.102 ± 0.474
0.0ArgXaa: 0.0 ± 0.0
Ser
5.08SerAla: 5.08 ± 0.635
0.963SerCys: 0.963 ± 0.297
3.503SerAsp: 3.503 ± 0.595
2.803SerGlu: 2.803 ± 0.581
2.803SerPhe: 2.803 ± 0.564
4.116SerGly: 4.116 ± 0.729
1.401SerHis: 1.401 ± 0.394
2.89SerIle: 2.89 ± 0.505
2.014SerLys: 2.014 ± 0.356
8.495SerLeu: 8.495 ± 1.096
1.576SerMet: 1.576 ± 0.474
2.978SerAsn: 2.978 ± 0.441
3.854SerPro: 3.854 ± 0.61
3.153SerGln: 3.153 ± 0.592
5.518SerArg: 5.518 ± 0.793
6.481SerSer: 6.481 ± 1.09
4.204SerThr: 4.204 ± 0.713
5.255SerVal: 5.255 ± 0.68
0.963SerTrp: 0.963 ± 0.325
2.978SerTyr: 2.978 ± 0.721
0.0SerXaa: 0.0 ± 0.0
Thr
4.642ThrAla: 4.642 ± 0.683
1.139ThrCys: 1.139 ± 0.414
2.365ThrAsp: 2.365 ± 0.542
2.452ThrGlu: 2.452 ± 0.482
3.065ThrPhe: 3.065 ± 0.515
3.065ThrGly: 3.065 ± 0.449
1.051ThrHis: 1.051 ± 0.287
3.591ThrIle: 3.591 ± 0.754
1.664ThrLys: 1.664 ± 0.369
6.744ThrLeu: 6.744 ± 0.692
0.876ThrMet: 0.876 ± 0.285
2.277ThrAsn: 2.277 ± 0.743
4.204ThrPro: 4.204 ± 0.656
2.014ThrGln: 2.014 ± 0.445
2.89ThrArg: 2.89 ± 0.459
3.766ThrSer: 3.766 ± 0.653
3.678ThrThr: 3.678 ± 0.645
4.642ThrVal: 4.642 ± 0.517
1.226ThrTrp: 1.226 ± 0.334
2.365ThrTyr: 2.365 ± 0.469
0.0ThrXaa: 0.0 ± 0.0
Val
4.642ValAla: 4.642 ± 0.625
1.314ValCys: 1.314 ± 0.32
3.328ValAsp: 3.328 ± 0.652
4.204ValGlu: 4.204 ± 0.609
3.503ValPhe: 3.503 ± 0.55
2.627ValGly: 2.627 ± 0.565
0.788ValHis: 0.788 ± 0.279
2.627ValIle: 2.627 ± 0.583
2.627ValLys: 2.627 ± 0.401
5.868ValLeu: 5.868 ± 0.622
1.489ValMet: 1.489 ± 0.342
3.153ValAsn: 3.153 ± 0.436
4.992ValPro: 4.992 ± 0.531
2.89ValGln: 2.89 ± 0.513
5.167ValArg: 5.167 ± 0.679
4.992ValSer: 4.992 ± 0.819
4.729ValThr: 4.729 ± 0.696
4.817ValVal: 4.817 ± 0.763
0.525ValTrp: 0.525 ± 0.206
3.416ValTyr: 3.416 ± 0.617
0.0ValXaa: 0.0 ± 0.0
Trp
0.263TrpAla: 0.263 ± 0.144
0.088TrpCys: 0.088 ± 0.105
1.314TrpAsp: 1.314 ± 0.388
1.051TrpGlu: 1.051 ± 0.275
0.438TrpPhe: 0.438 ± 0.246
0.876TrpGly: 0.876 ± 0.252
0.088TrpHis: 0.088 ± 0.086
0.175TrpIle: 0.175 ± 0.098
0.613TrpLys: 0.613 ± 0.22
1.314TrpLeu: 1.314 ± 0.355
0.175TrpMet: 0.175 ± 0.111
0.963TrpAsn: 0.963 ± 0.34
0.701TrpPro: 0.701 ± 0.198
0.438TrpGln: 0.438 ± 0.204
1.139TrpArg: 1.139 ± 0.334
1.839TrpSer: 1.839 ± 0.33
0.788TrpThr: 0.788 ± 0.249
0.263TrpVal: 0.263 ± 0.182
0.35TrpTrp: 0.35 ± 0.212
0.35TrpTyr: 0.35 ± 0.201
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.452TyrAla: 2.452 ± 0.542
0.701TyrCys: 0.701 ± 0.217
1.839TyrAsp: 1.839 ± 0.476
2.102TyrGlu: 2.102 ± 0.476
1.927TyrPhe: 1.927 ± 0.434
1.752TyrGly: 1.752 ± 0.429
1.314TyrHis: 1.314 ± 0.344
0.525TyrIle: 0.525 ± 0.213
1.576TyrLys: 1.576 ± 0.465
4.554TyrLeu: 4.554 ± 0.467
1.051TyrMet: 1.051 ± 0.296
1.664TyrAsn: 1.664 ± 0.5
2.54TyrPro: 2.54 ± 0.502
1.401TyrGln: 1.401 ± 0.346
2.365TyrArg: 2.365 ± 0.496
2.277TyrSer: 2.277 ± 0.568
1.927TyrThr: 1.927 ± 0.312
2.54TyrVal: 2.54 ± 0.42
0.35TyrTrp: 0.35 ± 0.169
0.701TyrTyr: 0.701 ± 0.298
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 36 proteins (11419 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski