Amino acid dipepetide frequency for Jeotgalibaca porci

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.064AlaAla: 6.064 ± 0.135
0.466AlaCys: 0.466 ± 0.028
4.172AlaAsp: 4.172 ± 0.085
5.398AlaGlu: 5.398 ± 0.107
3.408AlaPhe: 3.408 ± 0.07
5.158AlaGly: 5.158 ± 0.107
1.41AlaHis: 1.41 ± 0.048
6.254AlaIle: 6.254 ± 0.097
4.503AlaLys: 4.503 ± 0.086
7.366AlaLeu: 7.366 ± 0.118
2.148AlaMet: 2.148 ± 0.062
3.039AlaAsn: 3.039 ± 0.073
2.07AlaPro: 2.07 ± 0.07
2.477AlaGln: 2.477 ± 0.06
2.968AlaArg: 2.968 ± 0.07
3.988AlaSer: 3.988 ± 0.09
4.449AlaThr: 4.449 ± 0.093
5.564AlaVal: 5.564 ± 0.107
0.601AlaTrp: 0.601 ± 0.028
2.772AlaTyr: 2.772 ± 0.067
0.0AlaXaa: 0.0 ± 0.0
Cys
0.351CysAla: 0.351 ± 0.026
0.074CysCys: 0.074 ± 0.01
0.342CysAsp: 0.342 ± 0.025
0.345CysGlu: 0.345 ± 0.022
0.241CysPhe: 0.241 ± 0.02
0.6CysGly: 0.6 ± 0.033
0.155CysHis: 0.155 ± 0.016
0.339CysIle: 0.339 ± 0.019
0.221CysLys: 0.221 ± 0.02
0.456CysLeu: 0.456 ± 0.029
0.128CysMet: 0.128 ± 0.014
0.202CysAsn: 0.202 ± 0.02
0.285CysPro: 0.285 ± 0.026
0.229CysGln: 0.229 ± 0.02
0.249CysArg: 0.249 ± 0.019
0.303CysSer: 0.303 ± 0.021
0.253CysThr: 0.253 ± 0.02
0.295CysVal: 0.295 ± 0.023
0.042CysTrp: 0.042 ± 0.008
0.199CysTyr: 0.199 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
4.09AspAla: 4.09 ± 0.088
0.328AspCys: 0.328 ± 0.025
2.608AspAsp: 2.608 ± 0.07
4.529AspGlu: 4.529 ± 0.098
2.795AspPhe: 2.795 ± 0.069
3.647AspGly: 3.647 ± 0.091
0.916AspHis: 0.916 ± 0.039
4.178AspIle: 4.178 ± 0.078
3.268AspLys: 3.268 ± 0.077
5.241AspLeu: 5.241 ± 0.083
1.586AspMet: 1.586 ± 0.054
2.334AspAsn: 2.334 ± 0.06
1.915AspPro: 1.915 ± 0.05
1.66AspGln: 1.66 ± 0.048
2.133AspArg: 2.133 ± 0.059
2.957AspSer: 2.957 ± 0.072
3.156AspThr: 3.156 ± 0.07
3.907AspVal: 3.907 ± 0.072
0.64AspTrp: 0.64 ± 0.029
2.701AspTyr: 2.701 ± 0.073
0.0AspXaa: 0.0 ± 0.0
Glu
6.308GluAla: 6.308 ± 0.111
0.291GluCys: 0.291 ± 0.024
4.077GluAsp: 4.077 ± 0.08
7.239GluGlu: 7.239 ± 0.122
2.53GluPhe: 2.53 ± 0.065
4.374GluGly: 4.374 ± 0.086
1.237GluHis: 1.237 ± 0.044
5.874GluIle: 5.874 ± 0.102
6.096GluLys: 6.096 ± 0.1
6.944GluLeu: 6.944 ± 0.112
2.677GluMet: 2.677 ± 0.059
4.125GluAsn: 4.125 ± 0.089
2.145GluPro: 2.145 ± 0.051
3.022GluGln: 3.022 ± 0.073
3.467GluArg: 3.467 ± 0.069
4.0GluSer: 4.0 ± 0.082
4.746GluThr: 4.746 ± 0.087
5.285GluVal: 5.285 ± 0.102
0.817GluTrp: 0.817 ± 0.039
2.343GluTyr: 2.343 ± 0.063
0.0GluXaa: 0.0 ± 0.0
Phe
2.888PheAla: 2.888 ± 0.075
0.261PheCys: 0.261 ± 0.019
2.552PheAsp: 2.552 ± 0.064
3.214PheGlu: 3.214 ± 0.071
2.165PhePhe: 2.165 ± 0.063
3.254PheGly: 3.254 ± 0.076
0.808PheHis: 0.808 ± 0.035
3.421PheIle: 3.421 ± 0.086
2.298PheLys: 2.298 ± 0.064
4.125PheLeu: 4.125 ± 0.097
1.219PheMet: 1.219 ± 0.047
2.029PheAsn: 2.029 ± 0.061
1.611PhePro: 1.611 ± 0.053
1.562PheGln: 1.562 ± 0.047
1.663PheArg: 1.663 ± 0.044
3.235PheSer: 3.235 ± 0.079
2.754PheThr: 2.754 ± 0.073
3.232PheVal: 3.232 ± 0.071
0.466PheTrp: 0.466 ± 0.028
1.705PheTyr: 1.705 ± 0.057
0.0PheXaa: 0.0 ± 0.0
Gly
4.658GlyAla: 4.658 ± 0.098
0.36GlyCys: 0.36 ± 0.025
3.345GlyAsp: 3.345 ± 0.072
4.369GlyGlu: 4.369 ± 0.09
3.242GlyPhe: 3.242 ± 0.082
4.425GlyGly: 4.425 ± 0.09
1.309GlyHis: 1.309 ± 0.051
5.876GlyIle: 5.876 ± 0.104
4.485GlyLys: 4.485 ± 0.095
6.297GlyLeu: 6.297 ± 0.111
2.204GlyMet: 2.204 ± 0.061
2.923GlyAsn: 2.923 ± 0.063
1.589GlyPro: 1.589 ± 0.046
2.151GlyGln: 2.151 ± 0.059
2.673GlyArg: 2.673 ± 0.064
3.917GlySer: 3.917 ± 0.081
4.312GlyThr: 4.312 ± 0.089
4.907GlyVal: 4.907 ± 0.093
0.666GlyTrp: 0.666 ± 0.035
2.867GlyTyr: 2.867 ± 0.066
0.0GlyXaa: 0.0 ± 0.0
His
1.315HisAla: 1.315 ± 0.049
0.152HisCys: 0.152 ± 0.016
1.017HisAsp: 1.017 ± 0.039
1.297HisGlu: 1.297 ± 0.047
1.071HisPhe: 1.071 ± 0.039
1.29HisGly: 1.29 ± 0.045
0.535HisHis: 0.535 ± 0.034
1.388HisIle: 1.388 ± 0.046
0.851HisLys: 0.851 ± 0.038
1.949HisLeu: 1.949 ± 0.056
0.511HisMet: 0.511 ± 0.025
0.762HisAsn: 0.762 ± 0.034
0.982HisPro: 0.982 ± 0.042
0.698HisGln: 0.698 ± 0.034
0.795HisArg: 0.795 ± 0.036
1.049HisSer: 1.049 ± 0.04
1.103HisThr: 1.103 ± 0.04
1.354HisVal: 1.354 ± 0.048
0.191HisTrp: 0.191 ± 0.017
0.961HisTyr: 0.961 ± 0.037
0.0HisXaa: 0.0 ± 0.0
Ile
6.174IleAla: 6.174 ± 0.114
0.479IleCys: 0.479 ± 0.03
4.163IleAsp: 4.163 ± 0.089
5.63IleGlu: 5.63 ± 0.107
3.159IlePhe: 3.159 ± 0.069
5.394IleGly: 5.394 ± 0.103
1.443IleHis: 1.443 ± 0.046
5.752IleIle: 5.752 ± 0.121
4.282IleLys: 4.282 ± 0.105
7.21IleLeu: 7.21 ± 0.133
1.93IleMet: 1.93 ± 0.057
3.372IleAsn: 3.372 ± 0.068
3.21IlePro: 3.21 ± 0.07
3.016IleGln: 3.016 ± 0.07
3.03IleArg: 3.03 ± 0.067
4.973IleSer: 4.973 ± 0.09
4.544IleThr: 4.544 ± 0.089
5.261IleVal: 5.261 ± 0.103
0.619IleTrp: 0.619 ± 0.034
2.563IleTyr: 2.563 ± 0.065
0.0IleXaa: 0.0 ± 0.0
Lys
4.426LysAla: 4.426 ± 0.094
0.273LysCys: 0.273 ± 0.026
3.47LysAsp: 3.47 ± 0.076
6.184LysGlu: 6.184 ± 0.104
1.855LysPhe: 1.855 ± 0.047
3.822LysGly: 3.822 ± 0.071
1.142LysHis: 1.142 ± 0.041
4.197LysIle: 4.197 ± 0.092
4.857LysLys: 4.857 ± 0.097
5.125LysLeu: 5.125 ± 0.097
2.178LysMet: 2.178 ± 0.048
3.515LysAsn: 3.515 ± 0.077
1.924LysPro: 1.924 ± 0.057
2.757LysGln: 2.757 ± 0.061
3.281LysArg: 3.281 ± 0.068
3.081LysSer: 3.081 ± 0.067
3.483LysThr: 3.483 ± 0.078
4.119LysVal: 4.119 ± 0.074
0.669LysTrp: 0.669 ± 0.034
2.163LysTyr: 2.163 ± 0.059
0.0LysXaa: 0.0 ± 0.0
Leu
7.655LeuAla: 7.655 ± 0.118
0.496LeuCys: 0.496 ± 0.03
5.324LeuAsp: 5.324 ± 0.088
7.049LeuGlu: 7.049 ± 0.12
4.5LeuPhe: 4.5 ± 0.119
6.2LeuGly: 6.2 ± 0.104
1.696LeuHis: 1.696 ± 0.047
6.807LeuIle: 6.807 ± 0.126
5.794LeuLys: 5.794 ± 0.104
9.677LeuLeu: 9.677 ± 0.162
2.765LeuMet: 2.765 ± 0.068
4.47LeuAsn: 4.47 ± 0.08
3.715LeuPro: 3.715 ± 0.076
3.254LeuGln: 3.254 ± 0.067
3.668LeuArg: 3.668 ± 0.082
6.407LeuSer: 6.407 ± 0.099
6.062LeuThr: 6.062 ± 0.1
6.444LeuVal: 6.444 ± 0.109
0.729LeuTrp: 0.729 ± 0.036
3.185LeuTyr: 3.185 ± 0.073
0.0LeuXaa: 0.0 ± 0.0
Met
2.371MetAla: 2.371 ± 0.058
0.102MetCys: 0.102 ± 0.012
1.76MetAsp: 1.76 ± 0.059
1.999MetGlu: 1.999 ± 0.055
0.914MetPhe: 0.914 ± 0.038
2.008MetGly: 2.008 ± 0.055
0.511MetHis: 0.511 ± 0.027
2.12MetIle: 2.12 ± 0.061
2.166MetLys: 2.166 ± 0.059
2.433MetLeu: 2.433 ± 0.07
0.908MetMet: 0.908 ± 0.043
1.689MetAsn: 1.689 ± 0.046
1.13MetPro: 1.13 ± 0.041
1.052MetGln: 1.052 ± 0.039
1.241MetArg: 1.241 ± 0.044
1.644MetSer: 1.644 ± 0.059
2.007MetThr: 2.007 ± 0.053
1.876MetVal: 1.876 ± 0.051
0.218MetTrp: 0.218 ± 0.022
0.764MetTyr: 0.764 ± 0.031
0.0MetXaa: 0.0 ± 0.0
Asn
3.125AsnAla: 3.125 ± 0.079
0.252AsnCys: 0.252 ± 0.021
2.391AsnAsp: 2.391 ± 0.067
3.604AsnGlu: 3.604 ± 0.09
1.945AsnPhe: 1.945 ± 0.059
3.224AsnGly: 3.224 ± 0.077
1.145AsnHis: 1.145 ± 0.04
3.378AsnIle: 3.378 ± 0.072
3.055AsnLys: 3.055 ± 0.07
4.056AsnLeu: 4.056 ± 0.086
1.341AsnMet: 1.341 ± 0.041
2.204AsnAsn: 2.204 ± 0.064
2.272AsnPro: 2.272 ± 0.063
2.044AsnGln: 2.044 ± 0.061
2.373AsnArg: 2.373 ± 0.06
2.209AsnSer: 2.209 ± 0.059
2.323AsnThr: 2.323 ± 0.052
3.098AsnVal: 3.098 ± 0.076
0.53AsnTrp: 0.53 ± 0.029
1.853AsnTyr: 1.853 ± 0.054
0.0AsnXaa: 0.0 ± 0.0
Pro
2.448ProAla: 2.448 ± 0.069
0.157ProCys: 0.157 ± 0.017
2.162ProAsp: 2.162 ± 0.058
3.26ProGlu: 3.26 ± 0.078
1.844ProPhe: 1.844 ± 0.052
2.188ProGly: 2.188 ± 0.065
0.738ProHis: 0.738 ± 0.038
2.673ProIle: 2.673 ± 0.066
1.876ProLys: 1.876 ± 0.06
3.376ProLeu: 3.376 ± 0.084
0.847ProMet: 0.847 ± 0.038
1.62ProAsn: 1.62 ± 0.046
0.746ProPro: 0.746 ± 0.035
1.168ProGln: 1.168 ± 0.04
1.058ProArg: 1.058 ± 0.041
2.04ProSer: 2.04 ± 0.059
2.141ProThr: 2.141 ± 0.06
2.698ProVal: 2.698 ± 0.073
0.292ProTrp: 0.292 ± 0.025
1.431ProTyr: 1.431 ± 0.048
0.0ProXaa: 0.0 ± 0.0
Gln
3.004GlnAla: 3.004 ± 0.073
0.131GlnCys: 0.131 ± 0.015
1.689GlnAsp: 1.689 ± 0.053
2.875GlnGlu: 2.875 ± 0.077
1.553GlnPhe: 1.553 ± 0.052
1.953GlnGly: 1.953 ± 0.061
0.646GlnHis: 0.646 ± 0.03
2.662GlnIle: 2.662 ± 0.062
2.573GlnLys: 2.573 ± 0.069
3.884GlnLeu: 3.884 ± 0.083
1.172GlnMet: 1.172 ± 0.045
1.743GlnAsn: 1.743 ± 0.05
1.237GlnPro: 1.237 ± 0.044
1.543GlnGln: 1.543 ± 0.049
1.576GlnArg: 1.576 ± 0.051
2.055GlnSer: 2.055 ± 0.065
2.489GlnThr: 2.489 ± 0.066
2.493GlnVal: 2.493 ± 0.063
0.334GlnTrp: 0.334 ± 0.02
1.192GlnTyr: 1.192 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
2.579ArgAla: 2.579 ± 0.062
0.2ArgCys: 0.2 ± 0.02
2.16ArgAsp: 2.16 ± 0.061
3.221ArgGlu: 3.221 ± 0.074
1.975ArgPhe: 1.975 ± 0.062
2.334ArgGly: 2.334 ± 0.057
0.826ArgHis: 0.826 ± 0.037
3.563ArgIle: 3.563 ± 0.081
3.016ArgLys: 3.016 ± 0.069
4.14ArgLeu: 4.14 ± 0.091
1.428ArgMet: 1.428 ± 0.052
2.053ArgAsn: 2.053 ± 0.055
1.324ArgPro: 1.324 ± 0.054
1.598ArgGln: 1.598 ± 0.048
1.987ArgArg: 1.987 ± 0.068
2.2ArgSer: 2.2 ± 0.06
2.355ArgThr: 2.355 ± 0.052
2.838ArgVal: 2.838 ± 0.068
0.321ArgTrp: 0.321 ± 0.023
1.737ArgTyr: 1.737 ± 0.062
0.0ArgXaa: 0.0 ± 0.0
Ser
3.783SerAla: 3.783 ± 0.072
0.259SerCys: 0.259 ± 0.024
3.287SerAsp: 3.287 ± 0.072
4.574SerGlu: 4.574 ± 0.083
3.021SerPhe: 3.021 ± 0.073
4.434SerGly: 4.434 ± 0.093
1.178SerHis: 1.178 ± 0.038
4.224SerIle: 4.224 ± 0.093
3.455SerLys: 3.455 ± 0.072
5.888SerLeu: 5.888 ± 0.094
1.382SerMet: 1.382 ± 0.043
2.6SerAsn: 2.6 ± 0.069
1.832SerPro: 1.832 ± 0.057
2.133SerGln: 2.133 ± 0.064
2.48SerArg: 2.48 ± 0.06
3.376SerSer: 3.376 ± 0.083
3.135SerThr: 3.135 ± 0.072
4.142SerVal: 4.142 ± 0.079
0.563SerTrp: 0.563 ± 0.03
2.194SerTyr: 2.194 ± 0.061
0.0SerXaa: 0.0 ± 0.0
Thr
4.327ThrAla: 4.327 ± 0.086
0.274ThrCys: 0.274 ± 0.021
3.423ThrAsp: 3.423 ± 0.08
4.389ThrGlu: 4.389 ± 0.086
2.864ThrPhe: 2.864 ± 0.075
4.399ThrGly: 4.399 ± 0.086
1.258ThrHis: 1.258 ± 0.047
4.976ThrIle: 4.976 ± 0.076
3.364ThrLys: 3.364 ± 0.071
5.993ThrLeu: 5.993 ± 0.104
1.461ThrMet: 1.461 ± 0.044
2.531ThrAsn: 2.531 ± 0.068
2.427ThrPro: 2.427 ± 0.063
1.995ThrGln: 1.995 ± 0.066
2.147ThrArg: 2.147 ± 0.058
3.129ThrSer: 3.129 ± 0.063
3.498ThrThr: 3.498 ± 0.085
4.612ThrVal: 4.612 ± 0.088
0.487ThrTrp: 0.487 ± 0.031
2.252ThrTyr: 2.252 ± 0.057
0.0ThrXaa: 0.0 ± 0.0
Val
5.754ValAla: 5.754 ± 0.102
0.431ValCys: 0.431 ± 0.02
3.953ValAsp: 3.953 ± 0.073
5.038ValGlu: 5.038 ± 0.095
2.992ValPhe: 2.992 ± 0.074
4.741ValGly: 4.741 ± 0.085
1.269ValHis: 1.269 ± 0.041
5.384ValIle: 5.384 ± 0.106
3.98ValLys: 3.98 ± 0.083
6.817ValLeu: 6.817 ± 0.123
1.936ValMet: 1.936 ± 0.052
3.037ValAsn: 3.037 ± 0.063
2.667ValPro: 2.667 ± 0.067
2.272ValGln: 2.272 ± 0.061
2.762ValArg: 2.762 ± 0.063
4.732ValSer: 4.732 ± 0.083
4.447ValThr: 4.447 ± 0.085
5.327ValVal: 5.327 ± 0.098
0.6ValTrp: 0.6 ± 0.03
2.278ValTyr: 2.278 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
0.524TrpAla: 0.524 ± 0.029
0.053TrpCys: 0.053 ± 0.009
0.512TrpAsp: 0.512 ± 0.028
0.696TrpGlu: 0.696 ± 0.032
0.463TrpPhe: 0.463 ± 0.029
0.607TrpGly: 0.607 ± 0.03
0.184TrpHis: 0.184 ± 0.019
0.637TrpIle: 0.637 ± 0.029
0.571TrpLys: 0.571 ± 0.029
1.032TrpLeu: 1.032 ± 0.047
0.271TrpMet: 0.271 ± 0.02
0.508TrpAsn: 0.508 ± 0.03
0.221TrpPro: 0.221 ± 0.021
0.475TrpGln: 0.475 ± 0.026
0.472TrpArg: 0.472 ± 0.026
0.494TrpSer: 0.494 ± 0.025
0.453TrpThr: 0.453 ± 0.026
0.591TrpVal: 0.591 ± 0.03
0.098TrpTrp: 0.098 ± 0.015
0.348TrpTyr: 0.348 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.429TyrAla: 2.429 ± 0.062
0.271TyrCys: 0.271 ± 0.02
2.185TyrAsp: 2.185 ± 0.063
2.685TyrGlu: 2.685 ± 0.068
1.924TyrPhe: 1.924 ± 0.061
2.525TyrGly: 2.525 ± 0.077
0.866TyrHis: 0.866 ± 0.039
2.501TyrIle: 2.501 ± 0.062
1.811TyrLys: 1.811 ± 0.058
3.887TyrLeu: 3.887 ± 0.084
0.82TyrMet: 0.82 ± 0.037
1.665TyrAsn: 1.665 ± 0.044
1.458TyrPro: 1.458 ± 0.048
1.698TyrGln: 1.698 ± 0.048
1.835TyrArg: 1.835 ± 0.056
2.151TyrSer: 2.151 ± 0.061
2.097TyrThr: 2.097 ± 0.063
2.376TyrVal: 2.376 ± 0.06
0.325TyrTrp: 0.325 ± 0.023
1.665TyrTyr: 1.665 ± 0.051
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2201 proteins (663762 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski