Amino acid dipepetide frequency for Periplaneta fuliginosa densovirus (isolate Guo/2000) (PfDNV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.507AlaAla: 5.507 ± 2.096
0.459AlaCys: 0.459 ± 0.387
0.918AlaAsp: 0.918 ± 0.547
4.13AlaGlu: 4.13 ± 1.35
1.836AlaPhe: 1.836 ± 0.619
6.884AlaGly: 6.884 ± 1.735
0.459AlaHis: 0.459 ± 0.374
3.671AlaIle: 3.671 ± 1.452
3.671AlaLys: 3.671 ± 0.941
4.589AlaLeu: 4.589 ± 0.826
0.0AlaMet: 0.0 ± 0.0
2.754AlaAsn: 2.754 ± 1.098
1.377AlaPro: 1.377 ± 0.411
1.377AlaGln: 1.377 ± 1.0
4.13AlaArg: 4.13 ± 1.532
4.589AlaSer: 4.589 ± 2.239
3.212AlaThr: 3.212 ± 1.113
2.754AlaVal: 2.754 ± 1.129
0.0AlaTrp: 0.0 ± 0.0
1.836AlaTyr: 1.836 ± 1.18
0.0AlaXaa: 0.0 ± 0.0
Cys
1.377CysAla: 1.377 ± 0.447
0.0CysCys: 0.0 ± 0.0
2.295CysAsp: 2.295 ± 1.315
0.459CysGlu: 0.459 ± 0.374
0.918CysPhe: 0.918 ± 0.845
1.377CysGly: 1.377 ± 0.622
0.918CysHis: 0.918 ± 0.503
1.836CysIle: 1.836 ± 0.925
1.377CysLys: 1.377 ± 0.844
0.918CysLeu: 0.918 ± 0.503
0.918CysMet: 0.918 ± 0.748
1.377CysAsn: 1.377 ± 0.951
0.918CysPro: 0.918 ± 0.682
0.0CysGln: 0.0 ± 0.0
0.918CysArg: 0.918 ± 0.503
0.459CysSer: 0.459 ± 0.571
0.459CysThr: 0.459 ± 0.387
1.836CysVal: 1.836 ± 0.619
0.0CysTrp: 0.0 ± 0.0
1.377CysTyr: 1.377 ± 0.757
0.0CysXaa: 0.0 ± 0.0
Asp
4.13AspAla: 4.13 ± 1.174
0.918AspCys: 0.918 ± 0.774
6.425AspAsp: 6.425 ± 2.347
2.754AspGlu: 2.754 ± 1.182
1.836AspPhe: 1.836 ± 1.238
2.754AspGly: 2.754 ± 1.824
1.836AspHis: 1.836 ± 0.456
5.966AspIle: 5.966 ± 1.009
4.13AspLys: 4.13 ± 1.59
5.048AspLeu: 5.048 ± 1.597
1.377AspMet: 1.377 ± 0.755
2.754AspAsn: 2.754 ± 0.661
0.459AspPro: 0.459 ± 0.374
1.836AspGln: 1.836 ± 0.595
2.295AspArg: 2.295 ± 0.942
5.048AspSer: 5.048 ± 1.324
3.212AspThr: 3.212 ± 1.218
4.13AspVal: 4.13 ± 1.026
0.459AspTrp: 0.459 ± 0.422
2.295AspTyr: 2.295 ± 0.73
0.0AspXaa: 0.0 ± 0.0
Glu
2.295GluAla: 2.295 ± 1.381
1.836GluCys: 1.836 ± 0.895
3.671GluAsp: 3.671 ± 1.212
6.884GluGlu: 6.884 ± 2.364
0.459GluPhe: 0.459 ± 0.422
3.671GluGly: 3.671 ± 1.564
1.377GluHis: 1.377 ± 0.657
5.966GluIle: 5.966 ± 2.233
3.212GluLys: 3.212 ± 1.122
4.589GluLeu: 4.589 ± 1.358
1.377GluMet: 1.377 ± 0.749
2.295GluAsn: 2.295 ± 0.959
3.212GluPro: 3.212 ± 0.957
3.671GluGln: 3.671 ± 1.473
4.13GluArg: 4.13 ± 1.338
2.295GluSer: 2.295 ± 1.094
3.671GluThr: 3.671 ± 0.983
4.13GluVal: 4.13 ± 1.186
0.918GluTrp: 0.918 ± 0.732
2.754GluTyr: 2.754 ± 1.263
0.0GluXaa: 0.0 ± 0.0
Phe
1.836PheAla: 1.836 ± 0.664
0.918PheCys: 0.918 ± 0.484
2.754PheAsp: 2.754 ± 0.893
1.836PheGlu: 1.836 ± 0.456
1.836PhePhe: 1.836 ± 1.141
1.836PheGly: 1.836 ± 0.688
0.459PheHis: 0.459 ± 0.449
0.918PheIle: 0.918 ± 0.503
1.377PheLys: 1.377 ± 1.083
3.212PheLeu: 3.212 ± 1.235
0.918PheMet: 0.918 ± 0.774
1.377PheAsn: 1.377 ± 0.447
0.918PhePro: 0.918 ± 0.668
1.377PheGln: 1.377 ± 1.102
0.459PheArg: 0.459 ± 0.387
3.671PheSer: 3.671 ± 1.295
1.377PheThr: 1.377 ± 0.755
1.377PheVal: 1.377 ± 0.524
0.459PheTrp: 0.459 ± 0.465
1.377PheTyr: 1.377 ± 0.951
0.0PheXaa: 0.0 ± 0.0
Gly
3.212GlyAla: 3.212 ± 1.376
0.918GlyCys: 0.918 ± 0.866
1.836GlyAsp: 1.836 ± 0.995
3.212GlyGlu: 3.212 ± 0.781
3.212GlyPhe: 3.212 ± 1.322
5.507GlyGly: 5.507 ± 2.072
1.377GlyHis: 1.377 ± 0.464
2.754GlyIle: 2.754 ± 0.931
2.295GlyLys: 2.295 ± 1.016
5.048GlyLeu: 5.048 ± 2.653
0.918GlyMet: 0.918 ± 0.748
3.671GlyAsn: 3.671 ± 0.96
2.295GlyPro: 2.295 ± 0.627
2.295GlyGln: 2.295 ± 1.036
1.377GlyArg: 1.377 ± 0.679
3.212GlySer: 3.212 ± 1.706
6.884GlyThr: 6.884 ± 1.899
3.671GlyVal: 3.671 ± 0.988
0.918GlyTrp: 0.918 ± 0.508
3.212GlyTyr: 3.212 ± 1.056
0.0GlyXaa: 0.0 ± 0.0
His
0.459HisAla: 0.459 ± 0.465
1.377HisCys: 1.377 ± 0.981
1.836HisAsp: 1.836 ± 1.18
0.918HisGlu: 0.918 ± 0.503
0.459HisPhe: 0.459 ± 0.449
0.459HisGly: 0.459 ± 0.374
1.377HisHis: 1.377 ± 0.83
2.295HisIle: 2.295 ± 1.006
1.836HisLys: 1.836 ± 0.642
0.459HisLeu: 0.459 ± 0.58
0.459HisMet: 0.459 ± 0.58
0.918HisAsn: 0.918 ± 0.484
0.918HisPro: 0.918 ± 0.603
1.836HisGln: 1.836 ± 0.554
0.459HisArg: 0.459 ± 0.374
2.295HisSer: 2.295 ± 1.128
0.918HisThr: 0.918 ± 0.845
2.295HisVal: 2.295 ± 1.021
0.0HisTrp: 0.0 ± 0.0
1.377HisTyr: 1.377 ± 0.705
0.0HisXaa: 0.0 ± 0.0
Ile
3.671IleAla: 3.671 ± 0.787
1.836IleCys: 1.836 ± 1.153
3.212IleAsp: 3.212 ± 1.169
4.589IleGlu: 4.589 ± 1.579
0.459IlePhe: 0.459 ± 0.58
3.212IleGly: 3.212 ± 1.376
1.836IleHis: 1.836 ± 1.452
4.13IleIle: 4.13 ± 1.778
4.13IleLys: 4.13 ± 1.54
5.507IleLeu: 5.507 ± 2.021
1.377IleMet: 1.377 ± 0.557
1.836IleAsn: 1.836 ± 0.642
4.13IlePro: 4.13 ± 1.408
2.754IleGln: 2.754 ± 1.917
2.754IleArg: 2.754 ± 0.974
6.884IleSer: 6.884 ± 2.594
3.671IleThr: 3.671 ± 1.687
5.048IleVal: 5.048 ± 0.735
0.918IleTrp: 0.918 ± 0.759
1.836IleTyr: 1.836 ± 1.015
0.0IleXaa: 0.0 ± 0.0
Lys
3.212LysAla: 3.212 ± 0.957
0.918LysCys: 0.918 ± 0.388
3.671LysAsp: 3.671 ± 1.185
1.377LysGlu: 1.377 ± 0.677
0.459LysPhe: 0.459 ± 0.58
0.459LysGly: 0.459 ± 0.571
0.459LysHis: 0.459 ± 0.374
2.754LysIle: 2.754 ± 0.931
4.589LysLys: 4.589 ± 1.163
5.507LysLeu: 5.507 ± 2.014
1.377LysMet: 1.377 ± 0.428
4.13LysAsn: 4.13 ± 1.122
2.295LysPro: 2.295 ± 0.917
3.212LysGln: 3.212 ± 1.294
3.212LysArg: 3.212 ± 1.434
4.13LysSer: 4.13 ± 0.971
5.048LysThr: 5.048 ± 0.879
3.212LysVal: 3.212 ± 0.519
0.918LysTrp: 0.918 ± 0.93
2.754LysTyr: 2.754 ± 0.772
0.0LysXaa: 0.0 ± 0.0
Leu
5.048LeuAla: 5.048 ± 1.303
3.212LeuCys: 3.212 ± 1.566
2.754LeuAsp: 2.754 ± 1.057
5.966LeuGlu: 5.966 ± 2.568
1.836LeuPhe: 1.836 ± 1.012
3.212LeuGly: 3.212 ± 1.986
3.212LeuHis: 3.212 ± 0.879
4.13LeuIle: 4.13 ± 1.587
4.589LeuLys: 4.589 ± 1.598
8.72LeuLeu: 8.72 ± 3.139
2.295LeuMet: 2.295 ± 1.711
2.754LeuAsn: 2.754 ± 0.894
6.425LeuPro: 6.425 ± 1.725
5.507LeuGln: 5.507 ± 1.293
2.754LeuArg: 2.754 ± 1.093
5.048LeuSer: 5.048 ± 1.394
5.966LeuThr: 5.966 ± 1.271
2.754LeuVal: 2.754 ± 1.802
2.295LeuTrp: 2.295 ± 1.094
5.048LeuTyr: 5.048 ± 1.417
0.0LeuXaa: 0.0 ± 0.0
Met
1.836MetAla: 1.836 ± 0.826
0.918MetCys: 0.918 ± 0.503
0.459MetAsp: 0.459 ± 0.465
0.918MetGlu: 0.918 ± 0.488
0.0MetPhe: 0.0 ± 0.0
0.918MetGly: 0.918 ± 0.547
0.459MetHis: 0.459 ± 0.387
1.377MetIle: 1.377 ± 0.524
0.459MetLys: 0.459 ± 0.58
2.295MetLeu: 2.295 ± 0.695
0.0MetMet: 0.0 ± 0.0
3.212MetAsn: 3.212 ± 0.844
0.918MetPro: 0.918 ± 0.603
0.918MetGln: 0.918 ± 0.503
1.377MetArg: 1.377 ± 0.557
1.377MetSer: 1.377 ± 0.963
2.754MetThr: 2.754 ± 1.325
1.377MetVal: 1.377 ± 0.708
0.459MetTrp: 0.459 ± 0.58
0.459MetTyr: 0.459 ± 0.374
0.0MetXaa: 0.0 ± 0.0
Asn
3.671AsnAla: 3.671 ± 1.676
0.459AsnCys: 0.459 ± 0.374
2.754AsnAsp: 2.754 ± 1.188
4.13AsnGlu: 4.13 ± 0.854
2.295AsnPhe: 2.295 ± 0.885
4.13AsnGly: 4.13 ± 1.193
1.836AsnHis: 1.836 ± 1.145
1.836AsnIle: 1.836 ± 0.834
2.754AsnLys: 2.754 ± 1.164
2.295AsnLeu: 2.295 ± 0.746
1.377AsnMet: 1.377 ± 0.411
4.589AsnAsn: 4.589 ± 0.975
4.589AsnPro: 4.589 ± 1.501
1.377AsnGln: 1.377 ± 1.122
2.754AsnArg: 2.754 ± 0.985
1.836AsnSer: 1.836 ± 1.035
4.589AsnThr: 4.589 ± 1.559
2.754AsnVal: 2.754 ± 0.87
1.377AsnTrp: 1.377 ± 0.928
3.212AsnTyr: 3.212 ± 0.846
0.0AsnXaa: 0.0 ± 0.0
Pro
3.212ProAla: 3.212 ± 1.256
0.0ProCys: 0.0 ± 0.0
2.295ProAsp: 2.295 ± 0.981
1.836ProGlu: 1.836 ± 1.1
3.671ProPhe: 3.671 ± 0.905
2.295ProGly: 2.295 ± 0.648
0.0ProHis: 0.0 ± 0.0
3.212ProIle: 3.212 ± 1.515
2.295ProLys: 2.295 ± 0.917
6.425ProLeu: 6.425 ± 1.222
1.377ProMet: 1.377 ± 0.99
3.212ProAsn: 3.212 ± 0.817
3.212ProPro: 3.212 ± 1.574
1.836ProGln: 1.836 ± 0.604
1.836ProArg: 1.836 ± 0.766
2.295ProSer: 2.295 ± 0.566
2.295ProThr: 2.295 ± 0.852
4.589ProVal: 4.589 ± 1.812
0.459ProTrp: 0.459 ± 0.465
2.295ProTyr: 2.295 ± 0.839
0.0ProXaa: 0.0 ± 0.0
Gln
0.918GlnAla: 0.918 ± 0.774
0.918GlnCys: 0.918 ± 0.484
1.377GlnAsp: 1.377 ± 0.884
5.507GlnGlu: 5.507 ± 2.18
0.918GlnPhe: 0.918 ± 0.774
0.918GlnGly: 0.918 ± 0.503
0.918GlnHis: 0.918 ± 0.484
4.13GlnIle: 4.13 ± 0.821
2.754GlnLys: 2.754 ± 1.066
4.13GlnLeu: 4.13 ± 1.517
1.377GlnMet: 1.377 ± 0.406
0.918GlnAsn: 0.918 ± 0.584
2.754GlnPro: 2.754 ± 0.91
2.295GlnGln: 2.295 ± 0.938
2.754GlnArg: 2.754 ± 0.931
3.671GlnSer: 3.671 ± 1.568
3.671GlnThr: 3.671 ± 1.687
4.589GlnVal: 4.589 ± 2.248
1.836GlnTrp: 1.836 ± 0.636
0.459GlnTyr: 0.459 ± 0.374
0.0GlnXaa: 0.0 ± 0.0
Arg
2.754ArgAla: 2.754 ± 0.616
0.459ArgCys: 0.459 ± 0.387
3.671ArgAsp: 3.671 ± 1.639
2.754ArgGlu: 2.754 ± 1.136
1.836ArgPhe: 1.836 ± 1.015
2.754ArgGly: 2.754 ± 1.164
0.0ArgHis: 0.0 ± 0.0
3.671ArgIle: 3.671 ± 1.509
2.754ArgLys: 2.754 ± 1.175
2.754ArgLeu: 2.754 ± 1.96
1.836ArgMet: 1.836 ± 0.86
2.295ArgAsn: 2.295 ± 0.801
2.295ArgPro: 2.295 ± 0.993
2.295ArgGln: 2.295 ± 0.543
4.13ArgArg: 4.13 ± 2.465
2.754ArgSer: 2.754 ± 1.325
2.754ArgThr: 2.754 ± 0.754
3.212ArgVal: 3.212 ± 0.85
1.377ArgTrp: 1.377 ± 0.792
2.295ArgTyr: 2.295 ± 0.858
0.0ArgXaa: 0.0 ± 0.0
Ser
2.295SerAla: 2.295 ± 0.79
0.459SerCys: 0.459 ± 0.387
8.261SerAsp: 8.261 ± 1.857
6.884SerGlu: 6.884 ± 1.754
3.671SerPhe: 3.671 ± 1.134
4.13SerGly: 4.13 ± 1.721
1.377SerHis: 1.377 ± 0.835
4.13SerIle: 4.13 ± 0.664
3.212SerLys: 3.212 ± 1.256
6.884SerLeu: 6.884 ± 2.192
0.459SerMet: 0.459 ± 0.465
2.754SerAsn: 2.754 ± 0.56
2.295SerPro: 2.295 ± 1.103
3.212SerGln: 3.212 ± 1.197
3.671SerArg: 3.671 ± 1.393
9.179SerSer: 9.179 ± 2.672
3.212SerThr: 3.212 ± 0.838
6.884SerVal: 6.884 ± 2.784
0.459SerTrp: 0.459 ± 0.465
1.836SerTyr: 1.836 ± 1.165
0.0SerXaa: 0.0 ± 0.0
Thr
4.589ThrAla: 4.589 ± 1.033
1.836ThrCys: 1.836 ± 0.738
5.966ThrAsp: 5.966 ± 1.847
1.377ThrGlu: 1.377 ± 0.63
1.836ThrPhe: 1.836 ± 1.035
6.425ThrGly: 6.425 ± 2.044
1.836ThrHis: 1.836 ± 1.083
4.13ThrIle: 4.13 ± 1.633
0.918ThrLys: 0.918 ± 0.748
4.13ThrLeu: 4.13 ± 0.962
1.377ThrMet: 1.377 ± 0.967
4.589ThrAsn: 4.589 ± 0.933
2.754ThrPro: 2.754 ± 0.931
2.295ThrGln: 2.295 ± 1.14
2.754ThrArg: 2.754 ± 1.123
5.966ThrSer: 5.966 ± 1.731
4.589ThrThr: 4.589 ± 2.062
5.048ThrVal: 5.048 ± 1.614
0.0ThrTrp: 0.0 ± 0.0
4.13ThrTyr: 4.13 ± 1.394
0.0ThrXaa: 0.0 ± 0.0
Val
2.295ValAla: 2.295 ± 0.648
0.459ValCys: 0.459 ± 0.387
3.212ValAsp: 3.212 ± 0.807
2.754ValGlu: 2.754 ± 0.615
0.918ValPhe: 0.918 ± 0.759
3.671ValGly: 3.671 ± 1.543
2.295ValHis: 2.295 ± 0.728
5.048ValIle: 5.048 ± 2.225
3.212ValLys: 3.212 ± 1.325
5.507ValLeu: 5.507 ± 2.091
1.377ValMet: 1.377 ± 0.739
4.589ValAsn: 4.589 ± 1.016
3.212ValPro: 3.212 ± 1.176
4.589ValGln: 4.589 ± 1.609
3.212ValArg: 3.212 ± 0.795
4.13ValSer: 4.13 ± 1.293
5.048ValThr: 5.048 ± 1.695
5.048ValVal: 5.048 ± 1.251
0.918ValTrp: 0.918 ± 0.774
5.507ValTyr: 5.507 ± 1.195
0.0ValXaa: 0.0 ± 0.0
Trp
0.459TrpAla: 0.459 ± 0.465
0.459TrpCys: 0.459 ± 0.422
0.459TrpAsp: 0.459 ± 0.387
2.754TrpGlu: 2.754 ± 1.445
0.0TrpPhe: 0.0 ± 0.0
0.918TrpGly: 0.918 ± 0.594
0.0TrpHis: 0.0 ± 0.0
0.459TrpIle: 0.459 ± 0.58
2.295TrpLys: 2.295 ± 1.051
1.836TrpLeu: 1.836 ± 0.933
1.377TrpMet: 1.377 ± 0.963
0.918TrpAsn: 0.918 ± 0.503
0.918TrpPro: 0.918 ± 0.563
0.459TrpGln: 0.459 ± 0.387
0.459TrpArg: 0.459 ± 0.465
1.377TrpSer: 1.377 ± 0.62
0.459TrpThr: 0.459 ± 0.387
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.377TyrAla: 1.377 ± 0.657
1.377TyrCys: 1.377 ± 0.622
1.836TyrAsp: 1.836 ± 0.836
1.377TyrGlu: 1.377 ± 0.656
1.836TyrPhe: 1.836 ± 0.995
2.295TyrGly: 2.295 ± 0.696
0.918TyrHis: 0.918 ± 0.759
1.377TyrIle: 1.377 ± 0.828
1.836TyrLys: 1.836 ± 0.738
3.671TyrLeu: 3.671 ± 1.376
0.459TyrMet: 0.459 ± 0.374
3.671TyrAsn: 3.671 ± 1.174
2.754TyrPro: 2.754 ± 0.98
3.671TyrGln: 3.671 ± 1.279
3.212TyrArg: 3.212 ± 0.879
5.048TyrSer: 5.048 ± 1.208
3.212TyrThr: 3.212 ± 1.622
2.295TyrVal: 2.295 ± 1.033
1.836TyrTrp: 1.836 ± 0.976
2.295TyrTyr: 2.295 ± 1.644
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2180 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski