Amino acid dipepetide frequency for Escovopsis weberi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.684AlaAla: 13.684 ± 0.128	1.092AlaCys: 1.092 ± 0.02	5.412AlaAsp: 5.412 ± 0.044	6.034AlaGlu: 6.034 ± 0.062	3.282AlaPhe: 3.282 ± 0.035	7.355AlaGly: 7.355 ± 0.06	2.173AlaHis: 2.173 ± 0.029	4.118AlaIle: 4.118 ± 0.043	4.348AlaLys: 4.348 ± 0.049	8.744AlaLeu: 8.744 ± 0.061	2.211AlaMet: 2.211 ± 0.027	2.91AlaAsn: 2.91 ± 0.034	5.73AlaPro: 5.73 ± 0.063	3.898AlaGln: 3.898 ± 0.048	6.539AlaArg: 6.539 ± 0.056	7.932AlaSer: 7.932 ± 0.063	5.11AlaThr: 5.11 ± 0.045	6.026AlaVal: 6.026 ± 0.053	1.26AlaTrp: 1.26 ± 0.023	2.171AlaTyr: 2.171 ± 0.03	0.0AlaXaa: 0.0 ± 0.0
Cys	1.005CysAla: 1.005 ± 0.021	0.225CysCys: 0.225 ± 0.01	0.648CysAsp: 0.648 ± 0.015	0.58CysGlu: 0.58 ± 0.013	0.518CysPhe: 0.518 ± 0.013	0.932CysGly: 0.932 ± 0.021	0.305CysHis: 0.305 ± 0.01	0.599CysIle: 0.599 ± 0.014	0.439CysLys: 0.439 ± 0.014	1.19CysLeu: 1.19 ± 0.02	0.258CysMet: 0.258 ± 0.009	0.368CysAsn: 0.368 ± 0.012	0.639CysPro: 0.639 ± 0.015	0.402CysGln: 0.402 ± 0.011	0.746CysArg: 0.746 ± 0.016	0.81CysSer: 0.81 ± 0.016	0.587CysThr: 0.587 ± 0.014	0.778CysVal: 0.778 ± 0.018	0.176CysTrp: 0.176 ± 0.009	0.312CysTyr: 0.312 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.001AspAla: 6.001 ± 0.052	0.639AspCys: 0.639 ± 0.016	5.772AspAsp: 5.772 ± 0.077	5.108AspGlu: 5.108 ± 0.051	2.344AspPhe: 2.344 ± 0.03	4.825AspGly: 4.825 ± 0.042	1.35AspHis: 1.35 ± 0.025	2.771AspIle: 2.771 ± 0.03	2.592AspLys: 2.592 ± 0.033	5.212AspLeu: 5.212 ± 0.041	1.361AspMet: 1.361 ± 0.021	1.756AspAsn: 1.756 ± 0.024	3.437AspPro: 3.437 ± 0.038	1.928AspGln: 1.928 ± 0.026	3.389AspArg: 3.389 ± 0.035	3.936AspSer: 3.936 ± 0.038	2.542AspThr: 2.542 ± 0.024	3.975AspVal: 3.975 ± 0.036	0.852AspTrp: 0.852 ± 0.018	1.487AspTyr: 1.487 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	6.334GluAla: 6.334 ± 0.065	0.605GluCys: 0.605 ± 0.014	4.65GluAsp: 4.65 ± 0.048	6.01GluGlu: 6.01 ± 0.082	1.913GluPhe: 1.913 ± 0.027	4.097GluGly: 4.097 ± 0.044	1.482GluHis: 1.482 ± 0.026	2.816GluIle: 2.816 ± 0.033	3.561GluLys: 3.561 ± 0.045	5.333GluLeu: 5.333 ± 0.048	1.641GluMet: 1.641 ± 0.023	1.933GluAsn: 1.933 ± 0.027	2.83GluPro: 2.83 ± 0.031	2.522GluGln: 2.522 ± 0.034	4.397GluArg: 4.397 ± 0.05	3.911GluSer: 3.911 ± 0.039	3.285GluThr: 3.285 ± 0.033	3.522GluVal: 3.522 ± 0.041	0.858GluTrp: 0.858 ± 0.018	1.51GluTyr: 1.51 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.191PheAla: 3.191 ± 0.034	0.537PheCys: 0.537 ± 0.015	2.356PheAsp: 2.356 ± 0.029	2.187PheGlu: 2.187 ± 0.032	1.577PhePhe: 1.577 ± 0.027	2.787PheGly: 2.787 ± 0.038	0.891PheHis: 0.891 ± 0.016	1.603PheIle: 1.603 ± 0.027	1.408PheLys: 1.408 ± 0.022	3.368PheLeu: 3.368 ± 0.036	0.778PheMet: 0.778 ± 0.014	1.297PheAsn: 1.297 ± 0.023	1.786PhePro: 1.786 ± 0.023	1.276PheGln: 1.276 ± 0.017	2.121PheArg: 2.121 ± 0.028	2.782PheSer: 2.782 ± 0.032	1.911PheThr: 1.911 ± 0.027	2.423PheVal: 2.423 ± 0.027	0.611PheTrp: 0.611 ± 0.016	1.017PheTyr: 1.017 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	6.724GlyAla: 6.724 ± 0.064	0.849GlyCys: 0.849 ± 0.016	4.213GlyAsp: 4.213 ± 0.045	4.101GlyGlu: 4.101 ± 0.038	2.801GlyPhe: 2.801 ± 0.034	7.427GlyGly: 7.427 ± 0.097	1.847GlyHis: 1.847 ± 0.027	3.282GlyIle: 3.282 ± 0.037	3.391GlyLys: 3.391 ± 0.034	6.271GlyLeu: 6.271 ± 0.047	1.692GlyMet: 1.692 ± 0.024	2.428GlyAsn: 2.428 ± 0.033	3.723GlyPro: 3.723 ± 0.048	2.649GlyGln: 2.649 ± 0.031	4.841GlyArg: 4.841 ± 0.044	5.918GlySer: 5.918 ± 0.057	3.653GlyThr: 3.653 ± 0.038	4.467GlyVal: 4.467 ± 0.037	1.13GlyTrp: 1.13 ± 0.021	1.845GlyTyr: 1.845 ± 0.027	0.0GlyXaa: 0.0 ± 0.0
His	2.159HisAla: 2.159 ± 0.032	0.316HisCys: 0.316 ± 0.011	1.493HisAsp: 1.493 ± 0.027	1.396HisGlu: 1.396 ± 0.025	0.918HisPhe: 0.918 ± 0.015	1.892HisGly: 1.892 ± 0.03	1.05HisHis: 1.05 ± 0.029	1.118HisIle: 1.118 ± 0.016	0.918HisLys: 0.918 ± 0.02	2.223HisLeu: 2.223 ± 0.028	0.511HisMet: 0.511 ± 0.014	0.803HisAsn: 0.803 ± 0.017	1.679HisPro: 1.679 ± 0.024	1.066HisGln: 1.066 ± 0.025	1.61HisArg: 1.61 ± 0.022	1.679HisSer: 1.679 ± 0.028	1.087HisThr: 1.087 ± 0.02	1.459HisVal: 1.459 ± 0.021	0.321HisTrp: 0.321 ± 0.009	0.649HisTyr: 0.649 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.051IleAla: 4.051 ± 0.044	0.641IleCys: 0.641 ± 0.014	2.701IleAsp: 2.701 ± 0.034	2.682IleGlu: 2.682 ± 0.034	1.763IlePhe: 1.763 ± 0.028	2.919IleGly: 2.919 ± 0.041	1.088IleHis: 1.088 ± 0.018	2.135IleIle: 2.135 ± 0.034	2.083IleLys: 2.083 ± 0.029	4.171IleLeu: 4.171 ± 0.04	0.992IleMet: 0.992 ± 0.019	1.569IleAsn: 1.569 ± 0.023	2.662IlePro: 2.662 ± 0.035	1.66IleGln: 1.66 ± 0.028	2.821IleArg: 2.821 ± 0.031	3.288IleSer: 3.288 ± 0.032	2.402IleThr: 2.402 ± 0.031	2.937IleVal: 2.937 ± 0.038	0.615IleTrp: 0.615 ± 0.013	1.163IleTyr: 1.163 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.566LysAla: 4.566 ± 0.045	0.434LysCys: 0.434 ± 0.013	2.697LysAsp: 2.697 ± 0.037	3.199LysGlu: 3.199 ± 0.047	1.384LysPhe: 1.384 ± 0.022	2.875LysGly: 2.875 ± 0.035	1.083LysHis: 1.083 ± 0.018	2.072LysIle: 2.072 ± 0.031	3.422LysLys: 3.422 ± 0.06	3.887LysLeu: 3.887 ± 0.04	1.111LysMet: 1.111 ± 0.018	1.55LysAsn: 1.55 ± 0.02	2.553LysPro: 2.553 ± 0.03	1.825LysGln: 1.825 ± 0.028	3.359LysArg: 3.359 ± 0.039	3.088LysSer: 3.088 ± 0.033	2.658LysThr: 2.658 ± 0.028	2.586LysVal: 2.586 ± 0.032	0.599LysTrp: 0.599 ± 0.013	1.189LysTyr: 1.189 ± 0.022	0.001LysXaa: 0.001 ± 0.0
Leu	8.932LeuAla: 8.932 ± 0.067	1.137LeuCys: 1.137 ± 0.02	5.467LeuAsp: 5.467 ± 0.039	5.618LeuGlu: 5.618 ± 0.053	3.176LeuPhe: 3.176 ± 0.035	6.188LeuGly: 6.188 ± 0.05	2.158LeuHis: 2.158 ± 0.028	3.661LeuIle: 3.661 ± 0.036	3.958LeuLys: 3.958 ± 0.037	8.472LeuLeu: 8.472 ± 0.088	1.859LeuMet: 1.859 ± 0.025	2.871LeuAsn: 2.871 ± 0.028	5.255LeuPro: 5.255 ± 0.046	3.53LeuGln: 3.53 ± 0.038	6.407LeuArg: 6.407 ± 0.049	6.802LeuSer: 6.802 ± 0.057	4.47LeuThr: 4.47 ± 0.045	5.655LeuVal: 5.655 ± 0.049	1.138LeuTrp: 1.138 ± 0.018	2.159LeuTyr: 2.159 ± 0.03	0.0LeuXaa: 0.0 ± 0.0
Met	2.582MetAla: 2.582 ± 0.029	0.229MetCys: 0.229 ± 0.01	1.381MetAsp: 1.381 ± 0.018	1.317MetGlu: 1.317 ± 0.021	0.715MetPhe: 0.715 ± 0.016	1.604MetGly: 1.604 ± 0.019	0.467MetHis: 0.467 ± 0.012	0.935MetIle: 0.935 ± 0.018	0.952MetLys: 0.952 ± 0.017	1.947MetLeu: 1.947 ± 0.029	0.652MetMet: 0.652 ± 0.015	0.734MetAsn: 0.734 ± 0.014	1.322MetPro: 1.322 ± 0.024	0.88MetGln: 0.88 ± 0.018	1.493MetArg: 1.493 ± 0.023	1.818MetSer: 1.818 ± 0.024	1.332MetThr: 1.332 ± 0.022	1.342MetVal: 1.342 ± 0.022	0.267MetTrp: 0.267 ± 0.009	0.505MetTyr: 0.505 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.045AsnAla: 3.045 ± 0.032	0.374AsnCys: 0.374 ± 0.011	1.85AsnAsp: 1.85 ± 0.027	1.752AsnGlu: 1.752 ± 0.026	1.236AsnPhe: 1.236 ± 0.021	2.769AsnGly: 2.769 ± 0.035	0.787AsnHis: 0.787 ± 0.017	1.699AsnIle: 1.699 ± 0.026	1.417AsnLys: 1.417 ± 0.022	2.86AsnLeu: 2.86 ± 0.033	0.78AsnMet: 0.78 ± 0.017	1.525AsnAsn: 1.525 ± 0.049	2.159AsnPro: 2.159 ± 0.028	1.131AsnGln: 1.131 ± 0.017	1.809AsnArg: 1.809 ± 0.024	2.244AsnSer: 2.244 ± 0.032	1.708AsnThr: 1.708 ± 0.03	2.089AsnVal: 2.089 ± 0.028	0.453AsnTrp: 0.453 ± 0.013	0.897AsnTyr: 0.897 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.374ProAla: 6.374 ± 0.06	0.512ProCys: 0.512 ± 0.015	3.335ProAsp: 3.335 ± 0.032	3.764ProGlu: 3.764 ± 0.036	1.973ProPhe: 1.973 ± 0.024	4.26ProGly: 4.26 ± 0.044	1.356ProHis: 1.356 ± 0.02	2.174ProIle: 2.174 ± 0.028	2.436ProLys: 2.436 ± 0.034	4.666ProLeu: 4.666 ± 0.043	1.08ProMet: 1.08 ± 0.021	1.831ProAsn: 1.831 ± 0.025	5.319ProPro: 5.319 ± 0.083	2.317ProGln: 2.317 ± 0.04	3.792ProArg: 3.792 ± 0.042	5.648ProSer: 5.648 ± 0.063	3.37ProThr: 3.37 ± 0.038	3.391ProVal: 3.391 ± 0.034	0.7ProTrp: 0.7 ± 0.015	1.307ProTyr: 1.307 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.869GlnAla: 3.869 ± 0.045	0.379GlnCys: 0.379 ± 0.012	2.17GlnAsp: 2.17 ± 0.028	2.358GlnGlu: 2.358 ± 0.032	1.204GlnPhe: 1.204 ± 0.019	2.53GlnGly: 2.53 ± 0.026	1.158GlnHis: 1.158 ± 0.029	1.717GlnIle: 1.717 ± 0.021	1.778GlnLys: 1.778 ± 0.027	3.337GlnLeu: 3.337 ± 0.036	0.927GlnMet: 0.927 ± 0.017	1.247GlnAsn: 1.247 ± 0.019	2.399GlnPro: 2.399 ± 0.039	3.395GlnGln: 3.395 ± 0.105	2.773GlnArg: 2.773 ± 0.032	2.692GlnSer: 2.692 ± 0.031	2.042GlnThr: 2.042 ± 0.03	2.153GlnVal: 2.153 ± 0.028	0.525GlnTrp: 0.525 ± 0.013	0.993GlnTyr: 0.993 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	6.062ArgAla: 6.062 ± 0.048	0.738ArgCys: 0.738 ± 0.015	4.126ArgAsp: 4.126 ± 0.048	4.411ArgGlu: 4.411 ± 0.049	2.332ArgPhe: 2.332 ± 0.027	4.484ArgGly: 4.484 ± 0.043	1.752ArgHis: 1.752 ± 0.025	2.979ArgIle: 2.979 ± 0.029	3.391ArgLys: 3.391 ± 0.035	6.061ArgLeu: 6.061 ± 0.051	1.498ArgMet: 1.498 ± 0.022	2.105ArgAsn: 2.105 ± 0.025	3.86ArgPro: 3.86 ± 0.04	2.744ArgGln: 2.744 ± 0.032	5.985ArgArg: 5.985 ± 0.06	4.806ArgSer: 4.806 ± 0.044	3.191ArgThr: 3.191 ± 0.03	3.665ArgVal: 3.665 ± 0.032	0.951ArgTrp: 0.951 ± 0.019	1.61ArgTyr: 1.61 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	7.105SerAla: 7.105 ± 0.056	0.804SerCys: 0.804 ± 0.015	4.039SerAsp: 4.039 ± 0.041	3.777SerGlu: 3.777 ± 0.039	2.771SerPhe: 2.771 ± 0.031	5.589SerGly: 5.589 ± 0.047	1.852SerHis: 1.852 ± 0.026	3.482SerIle: 3.482 ± 0.035	3.403SerLys: 3.403 ± 0.036	6.91SerLeu: 6.91 ± 0.059	1.678SerMet: 1.678 ± 0.025	2.534SerAsn: 2.534 ± 0.032	5.112SerPro: 5.112 ± 0.057	2.914SerGln: 2.914 ± 0.032	5.168SerArg: 5.168 ± 0.047	8.73SerSer: 8.73 ± 0.102	4.444SerThr: 4.444 ± 0.041	4.355SerVal: 4.355 ± 0.04	1.026SerTrp: 1.026 ± 0.02	1.77SerTyr: 1.77 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.216ThrAla: 5.216 ± 0.046	0.634ThrCys: 0.634 ± 0.015	2.555ThrAsp: 2.555 ± 0.03	2.692ThrGlu: 2.692 ± 0.031	1.997ThrPhe: 1.997 ± 0.023	3.854ThrGly: 3.854 ± 0.044	1.169ThrHis: 1.169 ± 0.017	2.651ThrIle: 2.651 ± 0.03	2.259ThrLys: 2.259 ± 0.029	4.728ThrLeu: 4.728 ± 0.046	1.139ThrMet: 1.139 ± 0.018	1.702ThrAsn: 1.702 ± 0.027	3.782ThrPro: 3.782 ± 0.046	1.792ThrGln: 1.792 ± 0.026	3.118ThrArg: 3.118 ± 0.031	4.414ThrSer: 4.414 ± 0.046	3.899ThrThr: 3.899 ± 0.059	3.371ThrVal: 3.371 ± 0.041	0.717ThrTrp: 0.717 ± 0.015	1.319ThrTyr: 1.319 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	5.821ValAla: 5.821 ± 0.053	0.82ValCys: 0.82 ± 0.017	3.91ValAsp: 3.91 ± 0.034	3.936ValGlu: 3.936 ± 0.042	2.438ValPhe: 2.438 ± 0.031	4.109ValGly: 4.109 ± 0.038	1.361ValHis: 1.361 ± 0.02	2.719ValIle: 2.719 ± 0.036	2.731ValLys: 2.731 ± 0.028	5.807ValLeu: 5.807 ± 0.051	1.397ValMet: 1.397 ± 0.023	1.98ValAsn: 1.98 ± 0.028	3.548ValPro: 3.548 ± 0.036	2.228ValGln: 2.228 ± 0.028	3.787ValArg: 3.787 ± 0.033	4.324ValSer: 4.324 ± 0.041	3.211ValThr: 3.211 ± 0.04	4.548ValVal: 4.548 ± 0.051	0.838ValTrp: 0.838 ± 0.015	1.59ValTyr: 1.59 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.215TrpAla: 1.215 ± 0.021	0.186TrpCys: 0.186 ± 0.009	0.913TrpAsp: 0.913 ± 0.019	0.841TrpGlu: 0.841 ± 0.018	0.509TrpPhe: 0.509 ± 0.012	0.874TrpGly: 0.874 ± 0.018	0.338TrpHis: 0.338 ± 0.011	0.659TrpIle: 0.659 ± 0.018	0.669TrpLys: 0.669 ± 0.016	1.303TrpLeu: 1.303 ± 0.022	0.348TrpMet: 0.348 ± 0.01	0.528TrpAsn: 0.528 ± 0.013	0.57TrpPro: 0.57 ± 0.014	0.523TrpGln: 0.523 ± 0.014	1.015TrpArg: 1.015 ± 0.019	0.933TrpSer: 0.933 ± 0.02	0.819TrpThr: 0.819 ± 0.016	0.826TrpVal: 0.826 ± 0.017	0.26TrpTrp: 0.26 ± 0.009	0.366TrpTyr: 0.366 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.096TyrAla: 2.096 ± 0.028	0.365TyrCys: 0.365 ± 0.013	1.587TyrAsp: 1.587 ± 0.026	1.449TyrGlu: 1.449 ± 0.023	1.058TyrPhe: 1.058 ± 0.02	1.88TyrGly: 1.88 ± 0.031	0.681TyrHis: 0.681 ± 0.014	1.153TyrIle: 1.153 ± 0.019	0.982TyrLys: 0.982 ± 0.018	2.422TyrLeu: 2.422 ± 0.031	0.561TyrMet: 0.561 ± 0.013	0.913TyrAsn: 0.913 ± 0.019	1.239TyrPro: 1.239 ± 0.02	0.966TyrGln: 0.966 ± 0.019	1.577TyrArg: 1.577 ± 0.024	1.709TyrSer: 1.709 ± 0.025	1.286TyrThr: 1.286 ± 0.02	1.537TyrVal: 1.537 ± 0.023	0.398TyrTrp: 0.398 ± 0.012	0.782TyrTyr: 0.782 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.081XaaXaa: 0.081 ± 0.05

Statistics based on 6869 proteins (3220148 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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