Amino acid dipepetide frequency for Macaca mulatta feces associated virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.926AlaAla: 5.926 ± 0.117
0.0AlaCys: 0.0 ± 0.0
7.407AlaAsp: 7.407 ± 1.246
1.481AlaGlu: 1.481 ± 1.07
1.481AlaPhe: 1.481 ± 1.129
5.926AlaGly: 5.926 ± 2.316
1.481AlaHis: 1.481 ± 1.07
1.481AlaIle: 1.481 ± 1.129
1.481AlaLys: 1.481 ± 1.129
1.481AlaLeu: 1.481 ± 1.07
2.963AlaMet: 2.963 ± 2.14
1.481AlaAsn: 1.481 ± 1.129
2.963AlaPro: 2.963 ± 2.14
4.444AlaGln: 4.444 ± 1.011
4.444AlaArg: 4.444 ± 1.011
8.889AlaSer: 8.889 ± 2.023
1.481AlaThr: 1.481 ± 1.129
7.407AlaVal: 7.407 ± 1.246
1.481AlaTrp: 1.481 ± 1.07
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.963CysAla: 2.963 ± 2.14
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.481CysGlu: 1.481 ± 1.07
0.0CysPhe: 0.0 ± 0.0
1.481CysGly: 1.481 ± 1.07
1.481CysHis: 1.481 ± 1.07
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.481CysAsn: 1.481 ± 1.07
0.0CysPro: 0.0 ± 0.0
1.481CysGln: 1.481 ± 1.129
1.481CysArg: 1.481 ± 1.07
1.481CysSer: 1.481 ± 1.07
1.481CysThr: 1.481 ± 1.07
0.0CysVal: 0.0 ± 0.0
1.481CysTrp: 1.481 ± 1.07
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.481AspAla: 1.481 ± 1.129
2.963AspCys: 2.963 ± 0.059
0.0AspAsp: 0.0 ± 0.0
1.481AspGlu: 1.481 ± 1.129
0.0AspPhe: 0.0 ± 0.0
8.889AspGly: 8.889 ± 4.573
1.481AspHis: 1.481 ± 1.07
1.481AspIle: 1.481 ± 1.07
2.963AspLys: 2.963 ± 2.14
1.481AspLeu: 1.481 ± 1.129
1.481AspMet: 1.481 ± 0.727
2.963AspAsn: 2.963 ± 2.14
7.407AspPro: 7.407 ± 1.246
2.963AspGln: 2.963 ± 2.257
5.926AspArg: 5.926 ± 2.081
1.481AspSer: 1.481 ± 1.129
5.926AspThr: 5.926 ± 2.081
4.444AspVal: 4.444 ± 1.187
0.0AspTrp: 0.0 ± 0.0
1.481AspTyr: 1.481 ± 1.129
0.0AspXaa: 0.0 ± 0.0
Glu
5.926GluAla: 5.926 ± 0.117
1.481GluCys: 1.481 ± 1.07
5.926GluAsp: 5.926 ± 2.316
1.481GluGlu: 1.481 ± 1.07
0.0GluPhe: 0.0 ± 0.0
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
0.0GluLys: 0.0 ± 0.0
4.444GluLeu: 4.444 ± 1.187
1.481GluMet: 1.481 ± 1.129
1.481GluAsn: 1.481 ± 1.129
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
2.963GluArg: 2.963 ± 2.14
1.481GluSer: 1.481 ± 1.129
4.444GluThr: 4.444 ± 3.21
4.444GluVal: 4.444 ± 1.011
2.963GluTrp: 2.963 ± 2.14
1.481GluTyr: 1.481 ± 1.07
0.0GluXaa: 0.0 ± 0.0
Phe
1.481PheAla: 1.481 ± 1.07
0.0PheCys: 0.0 ± 0.0
1.481PheAsp: 1.481 ± 1.129
0.0PheGlu: 0.0 ± 0.0
4.444PhePhe: 4.444 ± 1.187
1.481PheGly: 1.481 ± 1.07
0.0PheHis: 0.0 ± 0.0
1.481PheIle: 1.481 ± 1.07
5.926PheLys: 5.926 ± 2.316
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
4.444PhePro: 4.444 ± 3.386
2.963PheGln: 2.963 ± 2.257
5.926PheArg: 5.926 ± 2.081
2.963PheSer: 2.963 ± 0.059
1.481PheThr: 1.481 ± 1.129
4.444PheVal: 4.444 ± 1.187
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.481GlyAla: 1.481 ± 1.129
1.481GlyCys: 1.481 ± 1.07
2.963GlyAsp: 2.963 ± 0.059
4.444GlyGlu: 4.444 ± 3.386
0.0GlyPhe: 0.0 ± 0.0
5.926GlyGly: 5.926 ± 4.515
2.963GlyHis: 2.963 ± 0.059
2.963GlyIle: 2.963 ± 2.14
1.481GlyLys: 1.481 ± 1.07
10.37GlyLeu: 10.37 ± 3.503
0.0GlyMet: 0.0 ± 0.0
2.963GlyAsn: 2.963 ± 0.059
4.444GlyPro: 4.444 ± 1.187
2.963GlyGln: 2.963 ± 0.059
2.963GlyArg: 2.963 ± 0.059
8.889GlySer: 8.889 ± 2.023
2.963GlyThr: 2.963 ± 2.257
7.407GlyVal: 7.407 ± 3.445
2.963GlyTrp: 2.963 ± 0.059
4.444GlyTyr: 4.444 ± 1.187
0.0GlyXaa: 0.0 ± 0.0
His
1.481HisAla: 1.481 ± 1.129
1.481HisCys: 1.481 ± 1.07
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.481HisGly: 1.481 ± 1.07
0.0HisHis: 0.0 ± 0.0
4.444HisIle: 4.444 ± 3.21
2.963HisLys: 2.963 ± 0.059
1.481HisLeu: 1.481 ± 1.07
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
2.963HisGln: 2.963 ± 2.257
1.481HisArg: 1.481 ± 1.129
0.0HisSer: 0.0 ± 0.0
2.963HisThr: 2.963 ± 2.14
0.0HisVal: 0.0 ± 0.0
1.481HisTrp: 1.481 ± 1.07
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.481IleCys: 1.481 ± 1.07
4.444IleAsp: 4.444 ± 1.187
2.963IleGlu: 2.963 ± 0.059
0.0IlePhe: 0.0 ± 0.0
1.481IleGly: 1.481 ± 1.129
0.0IleHis: 0.0 ± 0.0
2.963IleIle: 2.963 ± 0.059
2.963IleLys: 2.963 ± 2.14
0.0IleLeu: 0.0 ± 0.0
4.444IleMet: 4.444 ± 3.21
1.481IleAsn: 1.481 ± 1.07
5.926IlePro: 5.926 ± 0.117
4.444IleGln: 4.444 ± 1.011
2.963IleArg: 2.963 ± 2.14
2.963IleSer: 2.963 ± 0.059
4.444IleThr: 4.444 ± 1.187
2.963IleVal: 2.963 ± 0.059
1.481IleTrp: 1.481 ± 1.07
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.444LysAla: 4.444 ± 1.011
1.481LysCys: 1.481 ± 1.07
2.963LysAsp: 2.963 ± 2.14
1.481LysGlu: 1.481 ± 1.07
4.444LysPhe: 4.444 ± 1.011
2.963LysGly: 2.963 ± 0.059
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
1.481LysLys: 1.481 ± 1.07
7.407LysLeu: 7.407 ± 1.246
2.963LysMet: 2.963 ± 2.257
0.0LysAsn: 0.0 ± 0.0
4.444LysPro: 4.444 ± 1.011
1.481LysGln: 1.481 ± 1.07
2.963LysArg: 2.963 ± 2.257
4.444LysSer: 4.444 ± 1.011
5.926LysThr: 5.926 ± 2.081
2.963LysVal: 2.963 ± 0.059
5.926LysTrp: 5.926 ± 2.081
1.481LysTyr: 1.481 ± 1.129
0.0LysXaa: 0.0 ± 0.0
Leu
1.481LeuAla: 1.481 ± 1.129
0.0LeuCys: 0.0 ± 0.0
2.963LeuAsp: 2.963 ± 0.059
2.963LeuGlu: 2.963 ± 2.14
7.407LeuPhe: 7.407 ± 0.953
4.444LeuGly: 4.444 ± 1.187
2.963LeuHis: 2.963 ± 2.257
1.481LeuIle: 1.481 ± 1.07
2.963LeuLys: 2.963 ± 0.059
2.963LeuLeu: 2.963 ± 0.059
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
5.926LeuPro: 5.926 ± 4.515
5.926LeuGln: 5.926 ± 0.117
1.481LeuArg: 1.481 ± 1.07
5.926LeuSer: 5.926 ± 0.117
8.889LeuThr: 8.889 ± 2.375
1.481LeuVal: 1.481 ± 1.07
0.0LeuTrp: 0.0 ± 0.0
5.926LeuTyr: 5.926 ± 2.081
0.0LeuXaa: 0.0 ± 0.0
Met
1.481MetAla: 1.481 ± 1.07
1.481MetCys: 1.481 ± 1.07
0.0MetAsp: 0.0 ± 0.0
2.963MetGlu: 2.963 ± 2.14
0.0MetPhe: 0.0 ± 0.0
1.481MetGly: 1.481 ± 1.07
1.481MetHis: 1.481 ± 1.129
2.963MetIle: 2.963 ± 2.257
1.481MetLys: 1.481 ± 1.129
1.481MetLeu: 1.481 ± 1.07
2.963MetMet: 2.963 ± 2.257
2.963MetAsn: 2.963 ± 2.14
1.481MetPro: 1.481 ± 1.129
1.481MetGln: 1.481 ± 1.129
0.0MetArg: 0.0 ± 0.0
1.481MetSer: 1.481 ± 1.129
1.481MetThr: 1.481 ± 1.07
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
2.963MetTyr: 2.963 ± 0.059
0.0MetXaa: 0.0 ± 0.0
Asn
1.481AsnAla: 1.481 ± 1.07
0.0AsnCys: 0.0 ± 0.0
5.926AsnAsp: 5.926 ± 2.081
0.0AsnGlu: 0.0 ± 0.0
1.481AsnPhe: 1.481 ± 1.129
4.444AsnGly: 4.444 ± 1.011
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
2.963AsnLys: 2.963 ± 0.059
2.963AsnLeu: 2.963 ± 2.257
1.481AsnMet: 1.481 ± 1.07
0.0AsnAsn: 0.0 ± 0.0
1.481AsnPro: 1.481 ± 1.129
1.481AsnGln: 1.481 ± 1.129
0.0AsnArg: 0.0 ± 0.0
4.444AsnSer: 4.444 ± 1.011
4.444AsnThr: 4.444 ± 1.011
1.481AsnVal: 1.481 ± 1.129
0.0AsnTrp: 0.0 ± 0.0
4.444AsnTyr: 4.444 ± 1.011
0.0AsnXaa: 0.0 ± 0.0
Pro
5.926ProAla: 5.926 ± 0.117
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
1.481ProGlu: 1.481 ± 1.07
4.444ProPhe: 4.444 ± 1.187
4.444ProGly: 4.444 ± 3.386
0.0ProHis: 0.0 ± 0.0
2.963ProIle: 2.963 ± 0.059
4.444ProLys: 4.444 ± 3.21
0.0ProLeu: 0.0 ± 0.0
2.963ProMet: 2.963 ± 2.257
1.481ProAsn: 1.481 ± 1.07
1.481ProPro: 1.481 ± 1.129
1.481ProGln: 1.481 ± 1.129
7.407ProArg: 7.407 ± 0.953
2.963ProSer: 2.963 ± 2.257
5.926ProThr: 5.926 ± 4.515
4.444ProVal: 4.444 ± 3.386
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
7.407GlnAla: 7.407 ± 3.151
0.0GlnCys: 0.0 ± 0.0
4.444GlnAsp: 4.444 ± 1.011
1.481GlnGlu: 1.481 ± 1.07
1.481GlnPhe: 1.481 ± 1.129
1.481GlnGly: 1.481 ± 1.07
2.963GlnHis: 2.963 ± 2.14
5.926GlnIle: 5.926 ± 0.117
1.481GlnLys: 1.481 ± 1.129
5.926GlnLeu: 5.926 ± 2.316
0.0GlnMet: 0.0 ± 0.749
1.481GlnAsn: 1.481 ± 1.129
1.481GlnPro: 1.481 ± 1.129
2.963GlnGln: 2.963 ± 0.059
4.444GlnArg: 4.444 ± 1.187
4.444GlnSer: 4.444 ± 1.187
2.963GlnThr: 2.963 ± 0.059
2.963GlnVal: 2.963 ± 0.059
1.481GlnTrp: 1.481 ± 1.129
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.0ArgCys: 0.0 ± 0.0
2.963ArgAsp: 2.963 ± 0.059
2.963ArgGlu: 2.963 ± 0.059
2.963ArgPhe: 2.963 ± 0.059
8.889ArgGly: 8.889 ± 0.176
0.0ArgHis: 0.0 ± 0.0
4.444ArgIle: 4.444 ± 1.011
5.926ArgLys: 5.926 ± 2.081
7.407ArgLeu: 7.407 ± 0.953
0.0ArgMet: 0.0 ± 0.0
2.963ArgAsn: 2.963 ± 0.059
2.963ArgPro: 2.963 ± 0.059
4.444ArgGln: 4.444 ± 3.21
2.963ArgArg: 2.963 ± 0.059
2.963ArgSer: 2.963 ± 0.059
1.481ArgThr: 1.481 ± 1.07
2.963ArgVal: 2.963 ± 0.059
2.963ArgTrp: 2.963 ± 0.059
2.963ArgTyr: 2.963 ± 0.059
0.0ArgXaa: 0.0 ± 0.0
Ser
10.37SerAla: 10.37 ± 3.503
1.481SerCys: 1.481 ± 1.07
2.963SerAsp: 2.963 ± 0.059
1.481SerGlu: 1.481 ± 1.07
0.0SerPhe: 0.0 ± 0.0
5.926SerGly: 5.926 ± 2.316
0.0SerHis: 0.0 ± 0.0
5.926SerIle: 5.926 ± 0.117
4.444SerLys: 4.444 ± 1.011
2.963SerLeu: 2.963 ± 2.14
1.481SerMet: 1.481 ± 1.129
4.444SerAsn: 4.444 ± 1.011
1.481SerPro: 1.481 ± 1.129
0.0SerGln: 0.0 ± 0.0
4.444SerArg: 4.444 ± 1.011
1.481SerSer: 1.481 ± 1.07
2.963SerThr: 2.963 ± 0.059
1.481SerVal: 1.481 ± 1.129
2.963SerTrp: 2.963 ± 2.14
4.444SerTyr: 4.444 ± 1.187
0.0SerXaa: 0.0 ± 0.0
Thr
1.481ThrAla: 1.481 ± 1.07
2.963ThrCys: 2.963 ± 2.14
2.963ThrAsp: 2.963 ± 2.257
2.963ThrGlu: 2.963 ± 2.257
2.963ThrPhe: 2.963 ± 2.14
5.926ThrGly: 5.926 ± 0.117
1.481ThrHis: 1.481 ± 1.07
2.963ThrIle: 2.963 ± 0.059
4.444ThrLys: 4.444 ± 1.187
4.444ThrLeu: 4.444 ± 1.011
0.0ThrMet: 0.0 ± 0.0
7.407ThrAsn: 7.407 ± 3.445
4.444ThrPro: 4.444 ± 1.187
1.481ThrGln: 1.481 ± 1.07
1.481ThrArg: 1.481 ± 1.129
2.963ThrSer: 2.963 ± 0.059
1.481ThrThr: 1.481 ± 1.129
13.333ThrVal: 13.333 ± 0.835
4.444ThrTrp: 4.444 ± 3.21
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
7.407ValAla: 7.407 ± 0.953
0.0ValCys: 0.0 ± 0.0
4.444ValAsp: 4.444 ± 1.187
1.481ValGlu: 1.481 ± 1.129
2.963ValPhe: 2.963 ± 2.257
2.963ValGly: 2.963 ± 2.257
4.444ValHis: 4.444 ± 1.011
4.444ValIle: 4.444 ± 1.011
4.444ValLys: 4.444 ± 1.011
4.444ValLeu: 4.444 ± 1.187
0.0ValMet: 0.0 ± 0.0
4.444ValAsn: 4.444 ± 1.187
1.481ValPro: 1.481 ± 1.07
7.407ValGln: 7.407 ± 3.151
2.963ValArg: 2.963 ± 0.059
1.481ValSer: 1.481 ± 1.129
4.444ValThr: 4.444 ± 1.187
8.889ValVal: 8.889 ± 2.023
1.481ValTrp: 1.481 ± 1.07
5.926ValTyr: 5.926 ± 4.515
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.481TrpGlu: 1.481 ± 1.07
2.963TrpPhe: 2.963 ± 2.257
1.481TrpGly: 1.481 ± 1.07
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.481TrpLys: 1.481 ± 1.07
4.444TrpLeu: 4.444 ± 3.21
4.444TrpMet: 4.444 ± 1.011
1.481TrpAsn: 1.481 ± 1.07
0.0TrpPro: 0.0 ± 0.0
4.444TrpGln: 4.444 ± 1.187
2.963TrpArg: 2.963 ± 2.14
0.0TrpSer: 0.0 ± 0.0
2.963TrpThr: 2.963 ± 2.14
2.963TrpVal: 2.963 ± 2.14
0.0TrpTrp: 0.0 ± 0.0
1.481TrpTyr: 1.481 ± 1.07
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.481TyrAla: 1.481 ± 1.129
0.0TyrCys: 0.0 ± 0.0
4.444TyrAsp: 4.444 ± 1.011
5.926TyrGlu: 5.926 ± 0.117
1.481TyrPhe: 1.481 ± 1.129
2.963TyrGly: 2.963 ± 0.059
1.481TyrHis: 1.481 ± 1.07
1.481TyrIle: 1.481 ± 1.07
5.926TyrLys: 5.926 ± 0.117
1.481TyrLeu: 1.481 ± 1.129
1.481TyrMet: 1.481 ± 1.07
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
1.481TyrGln: 1.481 ± 1.129
2.963TyrArg: 2.963 ± 2.257
0.0TyrSer: 0.0 ± 0.0
1.481TyrThr: 1.481 ± 1.129
1.481TyrVal: 1.481 ± 1.07
1.481TyrTrp: 1.481 ± 1.129
4.444TyrTyr: 4.444 ± 3.386
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (676 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski