Amino acid dipepetide frequency for Banna virus (strain Indonesia/JKT-6423/1980) (BAV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.896AlaAla: 4.896 ± 1.007
0.675AlaCys: 0.675 ± 0.274
4.39AlaAsp: 4.39 ± 1.157
3.377AlaGlu: 3.377 ± 0.694
1.857AlaPhe: 1.857 ± 0.366
3.039AlaGly: 3.039 ± 0.848
0.844AlaHis: 0.844 ± 0.337
3.208AlaIle: 3.208 ± 0.592
3.546AlaLys: 3.546 ± 0.631
6.416AlaLeu: 6.416 ± 1.028
2.026AlaMet: 2.026 ± 0.499
4.39AlaAsn: 4.39 ± 0.821
2.87AlaPro: 2.87 ± 0.808
2.701AlaGln: 2.701 ± 0.87
2.026AlaArg: 2.026 ± 0.682
4.727AlaSer: 4.727 ± 0.824
4.559AlaThr: 4.559 ± 0.914
4.559AlaVal: 4.559 ± 0.838
0.507AlaTrp: 0.507 ± 0.252
2.533AlaTyr: 2.533 ± 0.696
0.0AlaXaa: 0.0 ± 0.0
Cys
0.507CysAla: 0.507 ± 0.267
0.507CysCys: 0.507 ± 0.278
0.507CysAsp: 0.507 ± 0.324
1.013CysGlu: 1.013 ± 0.495
0.675CysPhe: 0.675 ± 0.352
0.844CysGly: 0.844 ± 0.417
0.0CysHis: 0.0 ± 0.0
0.675CysIle: 0.675 ± 0.389
1.013CysLys: 1.013 ± 0.404
1.351CysLeu: 1.351 ± 0.35
1.013CysMet: 1.013 ± 0.447
0.844CysAsn: 0.844 ± 0.543
0.169CysPro: 0.169 ± 0.163
0.0CysGln: 0.0 ± 0.0
0.338CysArg: 0.338 ± 0.212
0.675CysSer: 0.675 ± 0.274
0.844CysThr: 0.844 ± 0.351
1.351CysVal: 1.351 ± 0.462
0.0CysTrp: 0.0 ± 0.0
0.338CysTyr: 0.338 ± 0.293
0.0CysXaa: 0.0 ± 0.0
Asp
4.221AspAla: 4.221 ± 0.946
0.675AspCys: 0.675 ± 0.362
4.39AspAsp: 4.39 ± 0.793
5.74AspGlu: 5.74 ± 0.87
2.533AspPhe: 2.533 ± 0.57
5.234AspGly: 5.234 ± 1.064
1.857AspHis: 1.857 ± 0.487
6.585AspIle: 6.585 ± 1.416
3.039AspLys: 3.039 ± 1.136
4.052AspLeu: 4.052 ± 1.431
1.52AspMet: 1.52 ± 0.459
3.208AspAsn: 3.208 ± 0.71
2.87AspPro: 2.87 ± 0.538
1.013AspGln: 1.013 ± 0.352
3.377AspArg: 3.377 ± 0.365
3.208AspSer: 3.208 ± 0.59
2.701AspThr: 2.701 ± 0.788
6.416AspVal: 6.416 ± 0.584
0.675AspTrp: 0.675 ± 0.299
2.701AspTyr: 2.701 ± 0.714
0.0AspXaa: 0.0 ± 0.0
Glu
2.195GluAla: 2.195 ± 0.339
0.844GluCys: 0.844 ± 0.483
2.364GluAsp: 2.364 ± 0.611
2.195GluGlu: 2.195 ± 0.442
1.688GluPhe: 1.688 ± 0.333
3.546GluGly: 3.546 ± 0.948
1.857GluHis: 1.857 ± 0.433
4.39GluIle: 4.39 ± 0.783
3.714GluLys: 3.714 ± 0.792
6.078GluLeu: 6.078 ± 0.638
1.182GluMet: 1.182 ± 0.397
3.039GluAsn: 3.039 ± 0.775
1.351GluPro: 1.351 ± 0.418
1.857GluGln: 1.857 ± 0.488
3.208GluArg: 3.208 ± 0.918
3.546GluSer: 3.546 ± 0.827
2.026GluThr: 2.026 ± 0.628
4.727GluVal: 4.727 ± 0.989
0.338GluTrp: 0.338 ± 0.186
3.208GluTyr: 3.208 ± 0.693
0.0GluXaa: 0.0 ± 0.0
Phe
2.701PheAla: 2.701 ± 0.497
0.338PheCys: 0.338 ± 0.173
3.208PheAsp: 3.208 ± 0.85
2.701PheGlu: 2.701 ± 0.649
1.013PhePhe: 1.013 ± 0.317
2.364PheGly: 2.364 ± 0.504
0.338PheHis: 0.338 ± 0.216
3.546PheIle: 3.546 ± 0.547
4.221PheLys: 4.221 ± 0.697
2.364PheLeu: 2.364 ± 0.665
0.844PheMet: 0.844 ± 0.432
3.208PheAsn: 3.208 ± 0.677
0.338PhePro: 0.338 ± 0.219
1.351PheGln: 1.351 ± 0.59
2.195PheArg: 2.195 ± 0.589
1.688PheSer: 1.688 ± 0.33
1.688PheThr: 1.688 ± 0.72
2.364PheVal: 2.364 ± 0.479
0.169PheTrp: 0.169 ± 0.163
0.844PheTyr: 0.844 ± 0.411
0.0PheXaa: 0.0 ± 0.0
Gly
1.857GlyAla: 1.857 ± 0.529
0.169GlyCys: 0.169 ± 0.214
2.026GlyAsp: 2.026 ± 0.518
1.351GlyGlu: 1.351 ± 0.303
2.026GlyPhe: 2.026 ± 0.448
2.701GlyGly: 2.701 ± 0.686
1.52GlyHis: 1.52 ± 0.303
3.377GlyIle: 3.377 ± 0.798
3.883GlyLys: 3.883 ± 0.769
6.753GlyLeu: 6.753 ± 1.194
0.844GlyMet: 0.844 ± 0.459
3.883GlyAsn: 3.883 ± 0.595
1.688GlyPro: 1.688 ± 0.472
2.195GlyGln: 2.195 ± 0.301
3.039GlyArg: 3.039 ± 0.883
5.909GlySer: 5.909 ± 0.808
3.039GlyThr: 3.039 ± 0.898
5.234GlyVal: 5.234 ± 0.756
0.338GlyTrp: 0.338 ± 0.226
2.026GlyTyr: 2.026 ± 0.646
0.0GlyXaa: 0.0 ± 0.0
His
1.857HisAla: 1.857 ± 0.457
0.338HisCys: 0.338 ± 0.194
2.533HisAsp: 2.533 ± 0.766
0.844HisGlu: 0.844 ± 0.308
1.013HisPhe: 1.013 ± 0.262
2.026HisGly: 2.026 ± 0.713
0.507HisHis: 0.507 ± 0.269
1.182HisIle: 1.182 ± 0.375
1.688HisLys: 1.688 ± 0.606
2.195HisLeu: 2.195 ± 0.686
0.675HisMet: 0.675 ± 0.47
0.844HisAsn: 0.844 ± 0.475
1.013HisPro: 1.013 ± 0.418
0.675HisGln: 0.675 ± 0.478
0.507HisArg: 0.507 ± 0.247
1.688HisSer: 1.688 ± 0.456
1.013HisThr: 1.013 ± 0.386
1.013HisVal: 1.013 ± 0.449
0.169HisTrp: 0.169 ± 0.181
1.182HisTyr: 1.182 ± 0.328
0.0HisXaa: 0.0 ± 0.0
Ile
4.39IleAla: 4.39 ± 1.168
0.844IleCys: 0.844 ± 0.502
5.909IleAsp: 5.909 ± 0.682
3.377IleGlu: 3.377 ± 0.515
1.857IlePhe: 1.857 ± 0.874
4.39IleGly: 4.39 ± 1.001
1.182IleHis: 1.182 ± 0.381
4.39IleIle: 4.39 ± 0.98
4.39IleLys: 4.39 ± 0.559
6.247IleLeu: 6.247 ± 1.156
1.857IleMet: 1.857 ± 0.625
4.896IleAsn: 4.896 ± 0.637
2.533IlePro: 2.533 ± 0.942
2.364IleGln: 2.364 ± 0.668
3.377IleArg: 3.377 ± 0.457
5.234IleSer: 5.234 ± 1.172
4.559IleThr: 4.559 ± 0.958
3.714IleVal: 3.714 ± 1.056
0.338IleTrp: 0.338 ± 0.186
1.857IleTyr: 1.857 ± 0.343
0.0IleXaa: 0.0 ± 0.0
Lys
2.701LysAla: 2.701 ± 0.636
0.507LysCys: 0.507 ± 0.373
4.727LysAsp: 4.727 ± 1.054
4.39LysGlu: 4.39 ± 0.901
2.533LysPhe: 2.533 ± 0.797
2.87LysGly: 2.87 ± 0.542
1.52LysHis: 1.52 ± 0.579
3.883LysIle: 3.883 ± 0.56
4.727LysLys: 4.727 ± 0.662
9.624LysLeu: 9.624 ± 0.982
2.701LysMet: 2.701 ± 0.63
3.208LysAsn: 3.208 ± 0.568
2.533LysPro: 2.533 ± 0.471
3.208LysGln: 3.208 ± 0.761
2.701LysArg: 2.701 ± 0.791
3.714LysSer: 3.714 ± 1.096
3.546LysThr: 3.546 ± 0.886
4.559LysVal: 4.559 ± 1.019
0.338LysTrp: 0.338 ± 0.269
2.195LysTyr: 2.195 ± 0.385
0.0LysXaa: 0.0 ± 0.0
Leu
6.416LeuAla: 6.416 ± 1.011
0.675LeuCys: 0.675 ± 0.395
7.766LeuAsp: 7.766 ± 1.543
4.727LeuGlu: 4.727 ± 0.777
2.195LeuPhe: 2.195 ± 0.605
2.87LeuGly: 2.87 ± 0.875
1.182LeuHis: 1.182 ± 0.56
6.585LeuIle: 6.585 ± 1.279
7.26LeuLys: 7.26 ± 0.941
6.585LeuLeu: 6.585 ± 1.138
2.026LeuMet: 2.026 ± 0.626
7.766LeuAsn: 7.766 ± 1.053
3.546LeuPro: 3.546 ± 0.879
1.688LeuGln: 1.688 ± 0.507
5.572LeuArg: 5.572 ± 0.893
7.598LeuSer: 7.598 ± 1.368
6.416LeuThr: 6.416 ± 1.237
7.091LeuVal: 7.091 ± 0.893
0.338LeuTrp: 0.338 ± 0.29
3.883LeuTyr: 3.883 ± 1.003
0.0LeuXaa: 0.0 ± 0.0
Met
2.195MetAla: 2.195 ± 0.518
0.507MetCys: 0.507 ± 0.338
1.52MetAsp: 1.52 ± 0.504
0.675MetGlu: 0.675 ± 0.204
1.013MetPhe: 1.013 ± 0.288
1.182MetGly: 1.182 ± 0.263
1.182MetHis: 1.182 ± 0.432
2.364MetIle: 2.364 ± 0.727
2.026MetLys: 2.026 ± 0.649
2.533MetLeu: 2.533 ± 0.678
0.675MetMet: 0.675 ± 0.279
1.52MetAsn: 1.52 ± 0.383
1.351MetPro: 1.351 ± 0.536
0.844MetGln: 0.844 ± 0.32
0.844MetArg: 0.844 ± 0.327
2.195MetSer: 2.195 ± 0.59
2.026MetThr: 2.026 ± 0.586
1.351MetVal: 1.351 ± 0.611
0.0MetTrp: 0.0 ± 0.0
0.844MetTyr: 0.844 ± 0.3
0.0MetXaa: 0.0 ± 0.0
Asn
4.052AsnAla: 4.052 ± 1.093
0.844AsnCys: 0.844 ± 0.439
4.221AsnAsp: 4.221 ± 1.325
3.546AsnGlu: 3.546 ± 0.659
3.039AsnPhe: 3.039 ± 0.72
5.065AsnGly: 5.065 ± 1.147
1.182AsnHis: 1.182 ± 0.307
5.572AsnIle: 5.572 ± 0.608
2.87AsnLys: 2.87 ± 0.475
5.572AsnLeu: 5.572 ± 1.116
1.52AsnMet: 1.52 ± 0.396
4.39AsnAsn: 4.39 ± 0.683
1.688AsnPro: 1.688 ± 0.759
2.87AsnGln: 2.87 ± 0.723
3.377AsnArg: 3.377 ± 0.585
5.065AsnSer: 5.065 ± 0.929
3.377AsnThr: 3.377 ± 0.839
5.234AsnVal: 5.234 ± 0.743
1.013AsnTrp: 1.013 ± 0.32
3.208AsnTyr: 3.208 ± 0.355
0.0AsnXaa: 0.0 ± 0.0
Pro
2.87ProAla: 2.87 ± 0.554
0.169ProCys: 0.169 ± 0.181
1.857ProAsp: 1.857 ± 0.365
1.857ProGlu: 1.857 ± 0.587
1.688ProPhe: 1.688 ± 0.703
1.351ProGly: 1.351 ± 0.412
1.52ProHis: 1.52 ± 0.378
1.351ProIle: 1.351 ± 0.326
1.857ProLys: 1.857 ± 0.625
3.714ProLeu: 3.714 ± 0.985
1.351ProMet: 1.351 ± 0.466
3.039ProAsn: 3.039 ± 0.69
0.0ProPro: 0.0 ± 0.0
0.675ProGln: 0.675 ± 0.25
1.52ProArg: 1.52 ± 0.586
1.182ProSer: 1.182 ± 0.363
1.857ProThr: 1.857 ± 0.606
3.546ProVal: 3.546 ± 0.847
0.169ProTrp: 0.169 ± 0.135
1.52ProTyr: 1.52 ± 0.641
0.0ProXaa: 0.0 ± 0.0
Gln
2.195GlnAla: 2.195 ± 0.612
0.507GlnCys: 0.507 ± 0.348
1.351GlnAsp: 1.351 ± 0.425
2.026GlnGlu: 2.026 ± 0.467
1.688GlnPhe: 1.688 ± 0.658
1.52GlnGly: 1.52 ± 0.499
1.182GlnHis: 1.182 ± 0.479
2.026GlnIle: 2.026 ± 0.563
1.52GlnLys: 1.52 ± 0.388
2.701GlnLeu: 2.701 ± 0.658
0.844GlnMet: 0.844 ± 0.372
2.195GlnAsn: 2.195 ± 0.636
0.507GlnPro: 0.507 ± 0.282
0.507GlnGln: 0.507 ± 0.302
1.52GlnArg: 1.52 ± 0.49
2.533GlnSer: 2.533 ± 1.005
1.351GlnThr: 1.351 ± 0.524
2.364GlnVal: 2.364 ± 0.606
0.507GlnTrp: 0.507 ± 0.283
1.182GlnTyr: 1.182 ± 0.311
0.0GlnXaa: 0.0 ± 0.0
Arg
4.39ArgAla: 4.39 ± 0.779
0.507ArgCys: 0.507 ± 0.39
2.701ArgAsp: 2.701 ± 0.554
2.533ArgGlu: 2.533 ± 0.645
2.195ArgPhe: 2.195 ± 0.495
2.195ArgGly: 2.195 ± 0.574
0.844ArgHis: 0.844 ± 0.361
3.039ArgIle: 3.039 ± 0.616
2.364ArgLys: 2.364 ± 0.533
4.727ArgLeu: 4.727 ± 0.768
0.844ArgMet: 0.844 ± 0.408
4.559ArgAsn: 4.559 ± 0.648
1.351ArgPro: 1.351 ± 0.495
0.844ArgGln: 0.844 ± 0.329
2.195ArgArg: 2.195 ± 0.515
3.377ArgSer: 3.377 ± 0.398
2.533ArgThr: 2.533 ± 0.603
3.377ArgVal: 3.377 ± 0.724
0.169ArgTrp: 0.169 ± 0.163
2.195ArgTyr: 2.195 ± 0.64
0.0ArgXaa: 0.0 ± 0.0
Ser
5.065SerAla: 5.065 ± 0.646
0.675SerCys: 0.675 ± 0.391
5.065SerAsp: 5.065 ± 0.828
3.714SerGlu: 3.714 ± 0.748
3.208SerPhe: 3.208 ± 0.427
3.714SerGly: 3.714 ± 0.901
2.026SerHis: 2.026 ± 0.478
4.052SerIle: 4.052 ± 1.121
5.234SerLys: 5.234 ± 0.771
6.922SerLeu: 6.922 ± 1.053
1.857SerMet: 1.857 ± 0.525
3.883SerAsn: 3.883 ± 0.748
2.701SerPro: 2.701 ± 0.667
2.195SerGln: 2.195 ± 0.598
3.377SerArg: 3.377 ± 0.762
6.078SerSer: 6.078 ± 0.923
4.052SerThr: 4.052 ± 0.967
5.572SerVal: 5.572 ± 0.729
0.844SerTrp: 0.844 ± 0.33
3.377SerTyr: 3.377 ± 0.622
0.0SerXaa: 0.0 ± 0.0
Thr
4.727ThrAla: 4.727 ± 0.812
0.844ThrCys: 0.844 ± 0.362
2.195ThrAsp: 2.195 ± 0.708
2.701ThrGlu: 2.701 ± 0.434
1.857ThrPhe: 1.857 ± 0.76
2.701ThrGly: 2.701 ± 0.619
1.182ThrHis: 1.182 ± 0.396
3.714ThrIle: 3.714 ± 0.731
3.714ThrLys: 3.714 ± 0.531
4.221ThrLeu: 4.221 ± 0.924
1.52ThrMet: 1.52 ± 0.565
3.208ThrAsn: 3.208 ± 0.998
2.026ThrPro: 2.026 ± 0.644
2.364ThrGln: 2.364 ± 0.478
2.195ThrArg: 2.195 ± 0.533
5.403ThrSer: 5.403 ± 0.834
4.39ThrThr: 4.39 ± 1.32
5.572ThrVal: 5.572 ± 0.708
0.0ThrTrp: 0.0 ± 0.0
3.546ThrTyr: 3.546 ± 0.718
0.0ThrXaa: 0.0 ± 0.0
Val
3.377ValAla: 3.377 ± 1.031
1.688ValCys: 1.688 ± 0.471
5.74ValAsp: 5.74 ± 0.935
4.727ValGlu: 4.727 ± 1.198
3.546ValPhe: 3.546 ± 0.567
4.221ValGly: 4.221 ± 0.767
1.857ValHis: 1.857 ± 0.508
4.727ValIle: 4.727 ± 0.885
5.403ValLys: 5.403 ± 0.977
5.065ValLeu: 5.065 ± 0.682
1.52ValMet: 1.52 ± 0.389
6.922ValAsn: 6.922 ± 0.871
2.87ValPro: 2.87 ± 1.049
2.195ValGln: 2.195 ± 0.646
2.87ValArg: 2.87 ± 0.618
5.234ValSer: 5.234 ± 0.74
5.403ValThr: 5.403 ± 0.981
7.598ValVal: 7.598 ± 0.93
0.169ValTrp: 0.169 ± 0.163
4.052ValTyr: 4.052 ± 0.659
0.0ValXaa: 0.0 ± 0.0
Trp
0.169TrpAla: 0.169 ± 0.135
0.169TrpCys: 0.169 ± 0.163
0.338TrpAsp: 0.338 ± 0.27
0.338TrpGlu: 0.338 ± 0.186
0.0TrpPhe: 0.0 ± 0.0
0.338TrpGly: 0.338 ± 0.186
0.169TrpHis: 0.169 ± 0.163
0.338TrpIle: 0.338 ± 0.186
0.338TrpLys: 0.338 ± 0.212
1.013TrpLeu: 1.013 ± 0.414
0.169TrpMet: 0.169 ± 0.202
0.338TrpAsn: 0.338 ± 0.202
0.338TrpPro: 0.338 ± 0.286
0.169TrpGln: 0.169 ± 0.135
0.169TrpArg: 0.169 ± 0.145
0.507TrpSer: 0.507 ± 0.19
0.507TrpThr: 0.507 ± 0.223
0.338TrpVal: 0.338 ± 0.186
0.0TrpTrp: 0.0 ± 0.0
0.338TrpTyr: 0.338 ± 0.222
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.364TyrAla: 2.364 ± 0.321
1.182TyrCys: 1.182 ± 0.425
3.208TyrAsp: 3.208 ± 0.656
1.52TyrGlu: 1.52 ± 0.505
2.026TyrPhe: 2.026 ± 0.619
1.688TyrGly: 1.688 ± 0.463
1.013TyrHis: 1.013 ± 0.508
2.701TyrIle: 2.701 ± 0.697
3.377TyrLys: 3.377 ± 0.933
4.052TyrLeu: 4.052 ± 1.093
1.688TyrMet: 1.688 ± 0.376
2.364TyrAsn: 2.364 ± 0.541
1.351TyrPro: 1.351 ± 0.48
0.507TyrGln: 0.507 ± 0.292
2.533TyrArg: 2.533 ± 0.884
4.052TyrSer: 4.052 ± 0.755
2.195TyrThr: 2.195 ± 0.429
3.208TyrVal: 3.208 ± 0.678
0.0TyrTrp: 0.0 ± 0.0
1.688TyrTyr: 1.688 ± 0.478
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (5924 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski