Amino acid dipepetide frequency for Nocardioides terrae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.899AlaAla: 19.899 ± 0.198	0.915AlaCys: 0.915 ± 0.027	8.732AlaAsp: 8.732 ± 0.09	7.922AlaGlu: 7.922 ± 0.1	3.627AlaPhe: 3.627 ± 0.056	12.611AlaGly: 12.611 ± 0.11	2.564AlaHis: 2.564 ± 0.053	4.642AlaIle: 4.642 ± 0.072	2.752AlaLys: 2.752 ± 0.06	13.702AlaLeu: 13.702 ± 0.138	2.607AlaMet: 2.607 ± 0.04	2.081AlaAsn: 2.081 ± 0.051	6.08AlaPro: 6.08 ± 0.086	3.575AlaGln: 3.575 ± 0.062	9.43AlaArg: 9.43 ± 0.109	6.694AlaSer: 6.694 ± 0.084	7.762AlaThr: 7.762 ± 0.08	12.057AlaVal: 12.057 ± 0.119	1.974AlaTrp: 1.974 ± 0.038	2.645AlaTyr: 2.645 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.825CysAla: 0.825 ± 0.026	0.075CysCys: 0.075 ± 0.008	0.439CysAsp: 0.439 ± 0.021	0.322CysGlu: 0.322 ± 0.015	0.2CysPhe: 0.2 ± 0.011	0.793CysGly: 0.793 ± 0.027	0.168CysHis: 0.168 ± 0.012	0.184CysIle: 0.184 ± 0.01	0.093CysLys: 0.093 ± 0.009	0.637CysLeu: 0.637 ± 0.024	0.084CysMet: 0.084 ± 0.008	0.13CysAsn: 0.13 ± 0.01	0.405CysPro: 0.405 ± 0.017	0.163CysGln: 0.163 ± 0.011	0.49CysArg: 0.49 ± 0.022	0.405CysSer: 0.405 ± 0.02	0.418CysThr: 0.418 ± 0.024	0.564CysVal: 0.564 ± 0.023	0.093CysTrp: 0.093 ± 0.01	0.162CysTyr: 0.162 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.994AspAla: 7.994 ± 0.091	0.343AspCys: 0.343 ± 0.017	4.489AspAsp: 4.489 ± 0.07	4.273AspGlu: 4.273 ± 0.066	1.638AspPhe: 1.638 ± 0.04	6.391AspGly: 6.391 ± 0.092	1.577AspHis: 1.577 ± 0.039	1.987AspIle: 1.987 ± 0.043	1.178AspLys: 1.178 ± 0.038	7.2AspLeu: 7.2 ± 0.079	0.857AspMet: 0.857 ± 0.028	1.076AspAsn: 1.076 ± 0.031	4.539AspPro: 4.539 ± 0.069	1.785AspGln: 1.785 ± 0.04	5.04AspArg: 5.04 ± 0.073	2.64AspSer: 2.64 ± 0.052	2.9AspThr: 2.9 ± 0.055	6.159AspVal: 6.159 ± 0.078	1.041AspTrp: 1.041 ± 0.035	1.274AspTyr: 1.274 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	7.14GluAla: 7.14 ± 0.108	0.327GluCys: 0.327 ± 0.017	2.813GluAsp: 2.813 ± 0.057	3.22GluGlu: 3.22 ± 0.063	1.397GluPhe: 1.397 ± 0.034	4.054GluGly: 4.054 ± 0.063	1.593GluHis: 1.593 ± 0.04	2.342GluIle: 2.342 ± 0.048	1.289GluLys: 1.289 ± 0.036	6.387GluLeu: 6.387 ± 0.085	1.02GluMet: 1.02 ± 0.028	0.891GluAsn: 0.891 ± 0.027	3.172GluPro: 3.172 ± 0.063	2.279GluGln: 2.279 ± 0.046	5.051GluArg: 5.051 ± 0.068	2.65GluSer: 2.65 ± 0.044	2.881GluThr: 2.881 ± 0.05	4.986GluVal: 4.986 ± 0.066	0.836GluTrp: 0.836 ± 0.023	0.855GluTyr: 0.855 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.738PheAla: 3.738 ± 0.054	0.24PheCys: 0.24 ± 0.012	2.195PheAsp: 2.195 ± 0.042	1.552PheGlu: 1.552 ± 0.037	0.91PhePhe: 0.91 ± 0.034	3.139PheGly: 3.139 ± 0.053	0.609PheHis: 0.609 ± 0.025	0.819PheIle: 0.819 ± 0.029	0.531PheLys: 0.531 ± 0.021	2.607PheLeu: 2.607 ± 0.059	0.423PheMet: 0.423 ± 0.017	0.582PheAsn: 0.582 ± 0.027	1.335PhePro: 1.335 ± 0.031	0.681PheGln: 0.681 ± 0.025	1.732PheArg: 1.732 ± 0.043	1.503PheSer: 1.503 ± 0.034	1.889PheThr: 1.889 ± 0.038	2.645PheVal: 2.645 ± 0.053	0.437PheTrp: 0.437 ± 0.021	0.624PheTyr: 0.624 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	10.49GlyAla: 10.49 ± 0.096	0.798GlyCys: 0.798 ± 0.029	5.56GlyAsp: 5.56 ± 0.081	4.734GlyGlu: 4.734 ± 0.07	2.962GlyPhe: 2.962 ± 0.05	8.102GlyGly: 8.102 ± 0.108	2.232GlyHis: 2.232 ± 0.048	3.773GlyIle: 3.773 ± 0.061	2.197GlyLys: 2.197 ± 0.041	9.751GlyLeu: 9.751 ± 0.107	1.897GlyMet: 1.897 ± 0.041	1.674GlyAsn: 1.674 ± 0.043	4.465GlyPro: 4.465 ± 0.068	2.546GlyGln: 2.546 ± 0.054	7.447GlyArg: 7.447 ± 0.094	5.641GlySer: 5.641 ± 0.085	5.568GlyThr: 5.568 ± 0.075	8.28GlyVal: 8.28 ± 0.093	1.813GlyTrp: 1.813 ± 0.039	2.262GlyTyr: 2.262 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.58HisAla: 2.58 ± 0.055	0.164HisCys: 0.164 ± 0.012	1.57HisAsp: 1.57 ± 0.043	1.252HisGlu: 1.252 ± 0.034	0.581HisPhe: 0.581 ± 0.021	2.291HisGly: 2.291 ± 0.045	0.709HisHis: 0.709 ± 0.032	0.597HisIle: 0.597 ± 0.023	0.327HisLys: 0.327 ± 0.016	2.402HisLeu: 2.402 ± 0.049	0.301HisMet: 0.301 ± 0.017	0.382HisAsn: 0.382 ± 0.019	1.647HisPro: 1.647 ± 0.038	0.646HisGln: 0.646 ± 0.024	1.899HisArg: 1.899 ± 0.039	0.928HisSer: 0.928 ± 0.029	1.111HisThr: 1.111 ± 0.032	2.02HisVal: 2.02 ± 0.044	0.366HisTrp: 0.366 ± 0.019	0.493HisTyr: 0.493 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.292IleAla: 5.292 ± 0.075	0.278IleCys: 0.278 ± 0.015	2.707IleAsp: 2.707 ± 0.044	2.215IleGlu: 2.215 ± 0.042	0.878IlePhe: 0.878 ± 0.03	3.976IleGly: 3.976 ± 0.071	0.617IleHis: 0.617 ± 0.024	1.065IleIle: 1.065 ± 0.031	0.813IleLys: 0.813 ± 0.031	2.768IleLeu: 2.768 ± 0.061	0.476IleMet: 0.476 ± 0.02	0.776IleAsn: 0.776 ± 0.027	1.809IlePro: 1.809 ± 0.045	0.791IleGln: 0.791 ± 0.028	2.315IleArg: 2.315 ± 0.049	1.946IleSer: 1.946 ± 0.042	2.286IleThr: 2.286 ± 0.044	3.529IleVal: 3.529 ± 0.062	0.419IleTrp: 0.419 ± 0.016	0.638IleTyr: 0.638 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	2.736LysAla: 2.736 ± 0.055	0.085LysCys: 0.085 ± 0.008	1.181LysAsp: 1.181 ± 0.035	1.002LysGlu: 1.002 ± 0.035	0.442LysPhe: 0.442 ± 0.02	1.724LysGly: 1.724 ± 0.048	0.453LysHis: 0.453 ± 0.019	0.849LysIle: 0.849 ± 0.031	0.805LysLys: 0.805 ± 0.036	1.833LysLeu: 1.833 ± 0.045	0.387LysMet: 0.387 ± 0.021	0.466LysAsn: 0.466 ± 0.021	1.203LysPro: 1.203 ± 0.037	0.727LysGln: 0.727 ± 0.028	1.489LysArg: 1.489 ± 0.042	1.094LysSer: 1.094 ± 0.035	1.183LysThr: 1.183 ± 0.037	2.071LysVal: 2.071 ± 0.047	0.228LysTrp: 0.228 ± 0.013	0.428LysTyr: 0.428 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	15.275LeuAla: 15.275 ± 0.123	0.688LeuCys: 0.688 ± 0.025	7.085LeuAsp: 7.085 ± 0.077	5.343LeuGlu: 5.343 ± 0.075	2.63LeuPhe: 2.63 ± 0.052	9.736LeuGly: 9.736 ± 0.1	2.201LeuHis: 2.201 ± 0.039	3.232LeuIle: 3.232 ± 0.062	1.799LeuLys: 1.799 ± 0.045	11.083LeuLeu: 11.083 ± 0.132	1.678LeuMet: 1.678 ± 0.037	1.584LeuAsn: 1.584 ± 0.041	5.923LeuPro: 5.923 ± 0.08	2.435LeuGln: 2.435 ± 0.042	7.852LeuArg: 7.852 ± 0.092	5.392LeuSer: 5.392 ± 0.06	6.564LeuThr: 6.564 ± 0.07	10.562LeuVal: 10.562 ± 0.105	1.249LeuTrp: 1.249 ± 0.035	1.589LeuTyr: 1.589 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.153MetAla: 2.153 ± 0.045	0.117MetCys: 0.117 ± 0.01	0.805MetAsp: 0.805 ± 0.025	0.726MetGlu: 0.726 ± 0.025	0.504MetPhe: 0.504 ± 0.018	1.375MetGly: 1.375 ± 0.035	0.337MetHis: 0.337 ± 0.013	0.671MetIle: 0.671 ± 0.023	0.448MetLys: 0.448 ± 0.021	1.812MetLeu: 1.812 ± 0.039	0.337MetMet: 0.337 ± 0.018	0.38MetAsn: 0.38 ± 0.017	1.09MetPro: 1.09 ± 0.03	0.479MetGln: 0.479 ± 0.022	1.428MetArg: 1.428 ± 0.033	1.49MetSer: 1.49 ± 0.038	1.756MetThr: 1.756 ± 0.035	1.496MetVal: 1.496 ± 0.039	0.207MetTrp: 0.207 ± 0.013	0.273MetTyr: 0.273 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.247AsnAla: 2.247 ± 0.042	0.13AsnCys: 0.13 ± 0.01	1.116AsnAsp: 1.116 ± 0.036	0.789AsnGlu: 0.789 ± 0.027	0.471AsnPhe: 0.471 ± 0.022	1.785AsnGly: 1.785 ± 0.048	0.392AsnHis: 0.392 ± 0.019	0.641AsnIle: 0.641 ± 0.025	0.395AsnLys: 0.395 ± 0.021	1.794AsnLeu: 1.794 ± 0.037	0.294AsnMet: 0.294 ± 0.015	0.437AsnAsn: 0.437 ± 0.021	1.398AsnPro: 1.398 ± 0.044	0.537AsnGln: 0.537 ± 0.024	1.244AsnArg: 1.244 ± 0.035	0.775AsnSer: 0.775 ± 0.026	1.035AsnThr: 1.035 ± 0.031	1.592AsnVal: 1.592 ± 0.04	0.253AsnTrp: 0.253 ± 0.015	0.394AsnTyr: 0.394 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	7.463ProAla: 7.463 ± 0.101	0.26ProCys: 0.26 ± 0.012	4.366ProAsp: 4.366 ± 0.069	3.691ProGlu: 3.691 ± 0.055	1.56ProPhe: 1.56 ± 0.034	5.477ProGly: 5.477 ± 0.066	1.209ProHis: 1.209 ± 0.032	1.77ProIle: 1.77 ± 0.038	1.056ProLys: 1.056 ± 0.035	4.989ProLeu: 4.989 ± 0.068	0.968ProMet: 0.968 ± 0.032	0.848ProAsn: 0.848 ± 0.03	2.714ProPro: 2.714 ± 0.064	1.463ProGln: 1.463 ± 0.04	3.481ProArg: 3.481 ± 0.059	3.235ProSer: 3.235 ± 0.053	3.657ProThr: 3.657 ± 0.054	5.169ProVal: 5.169 ± 0.063	0.912ProTrp: 0.912 ± 0.029	1.144ProTyr: 1.144 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.6GlnAla: 3.6 ± 0.062	0.141GlnCys: 0.141 ± 0.012	1.302GlnAsp: 1.302 ± 0.033	1.34GlnGlu: 1.34 ± 0.032	0.729GlnPhe: 0.729 ± 0.025	2.116GlnGly: 2.116 ± 0.046	0.679GlnHis: 0.679 ± 0.022	1.15GlnIle: 1.15 ± 0.032	0.557GlnLys: 0.557 ± 0.023	3.06GlnLeu: 3.06 ± 0.061	0.513GlnMet: 0.513 ± 0.019	0.481GlnAsn: 0.481 ± 0.023	1.641GlnPro: 1.641 ± 0.04	1.177GlnGln: 1.177 ± 0.036	2.518GlnArg: 2.518 ± 0.051	1.286GlnSer: 1.286 ± 0.036	1.433GlnThr: 1.433 ± 0.04	2.835GlnVal: 2.835 ± 0.049	0.44GlnTrp: 0.44 ± 0.021	0.43GlnTyr: 0.43 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	9.047ArgAla: 9.047 ± 0.099	0.443ArgCys: 0.443 ± 0.018	4.35ArgAsp: 4.35 ± 0.069	4.234ArgGlu: 4.234 ± 0.068	2.341ArgPhe: 2.341 ± 0.044	5.593ArgGly: 5.593 ± 0.076	1.899ArgHis: 1.899 ± 0.043	3.26ArgIle: 3.26 ± 0.05	1.459ArgLys: 1.459 ± 0.042	8.559ArgLeu: 8.559 ± 0.103	1.751ArgMet: 1.751 ± 0.042	1.33ArgAsn: 1.33 ± 0.039	4.364ArgPro: 4.364 ± 0.068	2.162ArgGln: 2.162 ± 0.046	7.48ArgArg: 7.48 ± 0.106	4.292ArgSer: 4.292 ± 0.06	4.717ArgThr: 4.717 ± 0.068	6.154ArgVal: 6.154 ± 0.075	1.37ArgTrp: 1.37 ± 0.034	1.565ArgTyr: 1.565 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	6.737SerAla: 6.737 ± 0.084	0.34SerCys: 0.34 ± 0.018	3.181SerAsp: 3.181 ± 0.065	2.456SerGlu: 2.456 ± 0.042	1.738SerPhe: 1.738 ± 0.041	5.855SerGly: 5.855 ± 0.083	1.08SerHis: 1.08 ± 0.026	1.942SerIle: 1.942 ± 0.041	0.978SerLys: 0.978 ± 0.033	5.373SerLeu: 5.373 ± 0.067	1.226SerMet: 1.226 ± 0.032	0.986SerAsn: 0.986 ± 0.03	2.884SerPro: 2.884 ± 0.055	1.372SerGln: 1.372 ± 0.035	3.738SerArg: 3.738 ± 0.055	3.28SerSer: 3.28 ± 0.067	3.509SerThr: 3.509 ± 0.067	4.678SerVal: 4.678 ± 0.067	0.942SerTrp: 0.942 ± 0.028	1.34SerTyr: 1.34 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	7.733ThrAla: 7.733 ± 0.086	0.404ThrCys: 0.404 ± 0.017	3.667ThrAsp: 3.667 ± 0.057	2.917ThrGlu: 2.917 ± 0.05	1.869ThrPhe: 1.869 ± 0.038	6.151ThrGly: 6.151 ± 0.091	1.203ThrHis: 1.203 ± 0.028	2.286ThrIle: 2.286 ± 0.044	1.216ThrLys: 1.216 ± 0.036	5.931ThrLeu: 5.931 ± 0.071	0.987ThrMet: 0.987 ± 0.03	1.114ThrAsn: 1.114 ± 0.035	3.897ThrPro: 3.897 ± 0.058	1.456ThrGln: 1.456 ± 0.034	3.958ThrArg: 3.958 ± 0.056	3.526ThrSer: 3.526 ± 0.065	4.072ThrThr: 4.072 ± 0.063	6.077ThrVal: 6.077 ± 0.081	0.988ThrTrp: 0.988 ± 0.031	1.465ThrTyr: 1.465 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	12.9ValAla: 12.9 ± 0.136	0.621ValCys: 0.621 ± 0.026	6.314ValAsp: 6.314 ± 0.082	5.531ValGlu: 5.531 ± 0.075	2.504ValPhe: 2.504 ± 0.05	8.046ValGly: 8.046 ± 0.091	2.016ValHis: 2.016 ± 0.044	3.361ValIle: 3.361 ± 0.054	1.799ValLys: 1.799 ± 0.045	10.008ValLeu: 10.008 ± 0.129	1.56ValMet: 1.56 ± 0.042	1.758ValAsn: 1.758 ± 0.044	5.111ValPro: 5.111 ± 0.063	2.056ValGln: 2.056 ± 0.047	6.835ValArg: 6.835 ± 0.082	4.857ValSer: 4.857 ± 0.064	6.094ValThr: 6.094 ± 0.082	10.304ValVal: 10.304 ± 0.121	1.193ValTrp: 1.193 ± 0.032	1.482ValTyr: 1.482 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.684TrpAla: 1.684 ± 0.038	0.136TrpCys: 0.136 ± 0.011	0.835TrpAsp: 0.835 ± 0.026	0.693TrpGlu: 0.693 ± 0.025	0.552TrpPhe: 0.552 ± 0.024	1.064TrpGly: 1.064 ± 0.031	0.387TrpHis: 0.387 ± 0.017	0.574TrpIle: 0.574 ± 0.02	0.328TrpLys: 0.328 ± 0.018	1.901TrpLeu: 1.901 ± 0.049	0.315TrpMet: 0.315 ± 0.018	0.351TrpAsn: 0.351 ± 0.017	0.783TrpPro: 0.783 ± 0.029	0.538TrpGln: 0.538 ± 0.02	1.35TrpArg: 1.35 ± 0.036	0.992TrpSer: 0.992 ± 0.026	1.023TrpThr: 1.023 ± 0.028	1.249TrpVal: 1.249 ± 0.032	0.38TrpTrp: 0.38 ± 0.022	0.308TrpTyr: 0.308 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.737TyrAla: 2.737 ± 0.045	0.145TyrCys: 0.145 ± 0.009	1.674TyrAsp: 1.674 ± 0.039	0.97TyrGlu: 0.97 ± 0.031	0.657TyrPhe: 0.657 ± 0.024	1.913TyrGly: 1.913 ± 0.049	0.343TyrHis: 0.343 ± 0.016	0.447TyrIle: 0.447 ± 0.02	0.366TyrLys: 0.366 ± 0.02	2.101TyrLeu: 2.101 ± 0.043	0.202TyrMet: 0.202 ± 0.015	0.392TyrAsn: 0.392 ± 0.018	0.973TyrPro: 0.973 ± 0.03	0.562TyrGln: 0.562 ± 0.024	1.593TyrArg: 1.593 ± 0.041	1.009TyrSer: 1.009 ± 0.035	1.059TyrThr: 1.059 ± 0.033	1.926TyrVal: 1.926 ± 0.038	0.301TyrTrp: 0.301 ± 0.018	0.439TyrTyr: 0.439 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3705 proteins (1209282 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---