Amino acid dipepetide frequency for Measles virus (strain Edmonston) (MeV) (Subacute sclerose panencephalitis virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.286AlaAla: 4.286 ± 0.636
0.816AlaCys: 0.816 ± 0.325
2.449AlaAsp: 2.449 ± 0.688
3.878AlaGlu: 3.878 ± 1.108
2.041AlaPhe: 2.041 ± 0.745
3.673AlaGly: 3.673 ± 1.043
1.224AlaHis: 1.224 ± 0.491
4.082AlaIle: 4.082 ± 0.965
2.857AlaLys: 2.857 ± 0.337
7.347AlaLeu: 7.347 ± 1.098
1.837AlaMet: 1.837 ± 0.61
2.245AlaAsn: 2.245 ± 0.71
2.857AlaPro: 2.857 ± 0.782
1.633AlaGln: 1.633 ± 0.544
4.082AlaArg: 4.082 ± 1.059
5.306AlaSer: 5.306 ± 1.691
2.245AlaThr: 2.245 ± 0.671
5.306AlaVal: 5.306 ± 1.444
0.612AlaTrp: 0.612 ± 0.376
2.041AlaTyr: 2.041 ± 0.89
0.0AlaXaa: 0.0 ± 0.0
Cys
1.224CysAla: 1.224 ± 0.412
0.612CysCys: 0.612 ± 0.466
0.612CysAsp: 0.612 ± 0.276
0.612CysGlu: 0.612 ± 0.232
1.429CysPhe: 1.429 ± 0.435
0.816CysGly: 0.816 ± 0.517
0.612CysHis: 0.612 ± 0.395
0.612CysIle: 0.612 ± 0.254
1.224CysLys: 1.224 ± 0.63
1.224CysLeu: 1.224 ± 0.439
0.204CysMet: 0.204 ± 0.225
0.612CysAsn: 0.612 ± 0.269
0.612CysPro: 0.612 ± 0.269
1.02CysGln: 1.02 ± 0.646
0.612CysArg: 0.612 ± 0.392
1.224CysSer: 1.224 ± 0.274
1.02CysThr: 1.02 ± 0.515
1.633CysVal: 1.633 ± 0.608
0.0CysTrp: 0.0 ± 0.0
1.02CysTyr: 1.02 ± 0.352
0.0CysXaa: 0.0 ± 0.0
Asp
2.857AspAla: 2.857 ± 0.688
0.612AspCys: 0.612 ± 0.232
3.673AspAsp: 3.673 ± 0.861
2.245AspGlu: 2.245 ± 0.281
0.612AspPhe: 0.612 ± 0.325
1.633AspGly: 1.633 ± 0.419
1.633AspHis: 1.633 ± 0.623
4.082AspIle: 4.082 ± 0.904
2.857AspLys: 2.857 ± 0.506
6.327AspLeu: 6.327 ± 0.91
0.816AspMet: 0.816 ± 0.317
3.265AspAsn: 3.265 ± 0.725
4.286AspPro: 4.286 ± 0.751
2.449AspGln: 2.449 ± 0.834
3.265AspArg: 3.265 ± 0.699
3.469AspSer: 3.469 ± 0.695
3.061AspThr: 3.061 ± 0.447
4.694AspVal: 4.694 ± 0.725
0.408AspTrp: 0.408 ± 0.289
1.429AspTyr: 1.429 ± 0.277
0.0AspXaa: 0.0 ± 0.0
Glu
3.061GluAla: 3.061 ± 0.522
1.224GluCys: 1.224 ± 0.589
3.878GluAsp: 3.878 ± 0.942
2.653GluGlu: 2.653 ± 1.057
2.041GluPhe: 2.041 ± 0.585
3.265GluGly: 3.265 ± 0.896
0.816GluHis: 0.816 ± 0.615
4.694GluIle: 4.694 ± 0.709
2.857GluLys: 2.857 ± 0.82
6.531GluLeu: 6.531 ± 1.121
0.816GluMet: 0.816 ± 0.439
1.837GluAsn: 1.837 ± 0.783
2.245GluPro: 2.245 ± 0.607
1.633GluGln: 1.633 ± 0.269
1.429GluArg: 1.429 ± 0.336
5.51GluSer: 5.51 ± 1.067
4.898GluThr: 4.898 ± 1.36
3.265GluVal: 3.265 ± 0.399
1.429GluTrp: 1.429 ± 0.312
0.612GluTyr: 0.612 ± 0.259
0.0GluXaa: 0.0 ± 0.0
Phe
1.429PheAla: 1.429 ± 0.377
0.408PheCys: 0.408 ± 0.189
1.429PheAsp: 1.429 ± 0.34
1.02PheGlu: 1.02 ± 0.336
1.224PhePhe: 1.224 ± 0.775
2.041PheGly: 2.041 ± 0.68
0.816PheHis: 0.816 ± 0.243
3.265PheIle: 3.265 ± 1.204
1.837PheLys: 1.837 ± 0.567
3.265PheLeu: 3.265 ± 1.018
1.633PheMet: 1.633 ± 0.818
1.837PheAsn: 1.837 ± 0.527
0.612PhePro: 0.612 ± 0.273
1.02PheGln: 1.02 ± 0.38
2.857PheArg: 2.857 ± 1.071
1.837PheSer: 1.837 ± 0.494
1.633PheThr: 1.633 ± 0.65
2.653PheVal: 2.653 ± 1.038
0.816PheTrp: 0.816 ± 0.517
0.816PheTyr: 0.816 ± 0.486
0.0PheXaa: 0.0 ± 0.0
Gly
2.245GlyAla: 2.245 ± 0.782
0.408GlyCys: 0.408 ± 0.258
3.878GlyAsp: 3.878 ± 0.289
3.469GlyGlu: 3.469 ± 1.029
2.857GlyPhe: 2.857 ± 0.776
4.49GlyGly: 4.49 ± 0.93
1.633GlyHis: 1.633 ± 0.608
3.673GlyIle: 3.673 ± 1.088
2.857GlyLys: 2.857 ± 0.975
8.367GlyLeu: 8.367 ± 0.706
2.449GlyMet: 2.449 ± 0.64
3.265GlyAsn: 3.265 ± 0.655
3.061GlyPro: 3.061 ± 0.95
2.857GlyGln: 2.857 ± 0.852
3.469GlyArg: 3.469 ± 1.051
6.735GlySer: 6.735 ± 0.646
3.673GlyThr: 3.673 ± 1.078
5.51GlyVal: 5.51 ± 1.885
0.408GlyTrp: 0.408 ± 0.211
2.245GlyTyr: 2.245 ± 0.425
0.0GlyXaa: 0.0 ± 0.0
His
1.837HisAla: 1.837 ± 0.483
0.816HisCys: 0.816 ± 0.355
1.429HisAsp: 1.429 ± 0.733
1.429HisGlu: 1.429 ± 0.492
0.408HisPhe: 0.408 ± 0.189
1.02HisGly: 1.02 ± 0.421
0.408HisHis: 0.408 ± 0.258
2.245HisIle: 2.245 ± 0.671
0.612HisLys: 0.612 ± 0.259
2.245HisLeu: 2.245 ± 0.628
0.612HisMet: 0.612 ± 0.232
0.408HisAsn: 0.408 ± 0.189
1.02HisPro: 1.02 ± 0.437
1.429HisGln: 1.429 ± 0.511
2.245HisArg: 2.245 ± 0.637
1.429HisSer: 1.429 ± 0.492
1.224HisThr: 1.224 ± 0.61
0.816HisVal: 0.816 ± 0.262
0.408HisTrp: 0.408 ± 0.415
0.612HisTyr: 0.612 ± 0.388
0.0HisXaa: 0.0 ± 0.0
Ile
5.102IleAla: 5.102 ± 1.309
0.612IleCys: 0.612 ± 0.276
3.265IleAsp: 3.265 ± 0.657
3.673IleGlu: 3.673 ± 0.745
1.633IlePhe: 1.633 ± 0.648
5.918IleGly: 5.918 ± 1.182
2.245IleHis: 2.245 ± 0.598
4.082IleIle: 4.082 ± 0.754
6.327IleLys: 6.327 ± 0.72
6.122IleLeu: 6.122 ± 1.881
1.224IleMet: 1.224 ± 0.699
4.694IleAsn: 4.694 ± 0.665
3.673IlePro: 3.673 ± 0.478
2.857IleGln: 2.857 ± 0.498
4.082IleArg: 4.082 ± 0.41
6.327IleSer: 6.327 ± 1.224
4.694IleThr: 4.694 ± 0.583
4.082IleVal: 4.082 ± 0.695
0.204IleTrp: 0.204 ± 0.215
2.041IleTyr: 2.041 ± 0.745
0.0IleXaa: 0.0 ± 0.0
Lys
2.857LysAla: 2.857 ± 0.5
0.612LysCys: 0.612 ± 0.269
3.265LysAsp: 3.265 ± 0.812
4.286LysGlu: 4.286 ± 1.157
2.041LysPhe: 2.041 ± 0.519
4.49LysGly: 4.49 ± 0.836
0.816LysHis: 0.816 ± 0.376
4.082LysIle: 4.082 ± 1.138
2.653LysLys: 2.653 ± 0.987
6.531LysLeu: 6.531 ± 1.017
1.429LysMet: 1.429 ± 1.044
1.224LysAsn: 1.224 ± 0.282
2.245LysPro: 2.245 ± 1.29
1.224LysGln: 1.224 ± 0.43
2.653LysArg: 2.653 ± 0.562
3.469LysSer: 3.469 ± 0.543
1.633LysThr: 1.633 ± 0.947
3.469LysVal: 3.469 ± 0.773
0.408LysTrp: 0.408 ± 0.337
1.837LysTyr: 1.837 ± 0.639
0.0LysXaa: 0.0 ± 0.0
Leu
8.367LeuAla: 8.367 ± 1.235
1.837LeuCys: 1.837 ± 0.384
5.102LeuAsp: 5.102 ± 0.596
7.347LeuGlu: 7.347 ± 1.248
3.673LeuPhe: 3.673 ± 0.604
7.959LeuGly: 7.959 ± 1.963
3.265LeuHis: 3.265 ± 0.763
8.163LeuIle: 8.163 ± 1.936
7.347LeuLys: 7.347 ± 1.586
10.612LeuLeu: 10.612 ± 0.981
3.673LeuMet: 3.673 ± 0.559
3.469LeuAsn: 3.469 ± 0.584
2.653LeuPro: 2.653 ± 0.691
3.061LeuGln: 3.061 ± 0.943
6.122LeuArg: 6.122 ± 1.196
9.796LeuSer: 9.796 ± 2.028
5.714LeuThr: 5.714 ± 0.594
5.918LeuVal: 5.918 ± 1.144
1.429LeuTrp: 1.429 ± 0.902
3.061LeuTyr: 3.061 ± 0.915
0.0LeuXaa: 0.0 ± 0.0
Met
1.633MetAla: 1.633 ± 0.402
0.0MetCys: 0.0 ± 0.0
0.816MetAsp: 0.816 ± 0.298
0.816MetGlu: 0.816 ± 0.465
0.816MetPhe: 0.816 ± 0.421
2.041MetGly: 2.041 ± 0.513
0.408MetHis: 0.408 ± 0.211
2.041MetIle: 2.041 ± 0.347
1.429MetLys: 1.429 ± 0.502
2.449MetLeu: 2.449 ± 0.927
0.0MetMet: 0.0 ± 0.0
1.633MetAsn: 1.633 ± 0.367
1.02MetPro: 1.02 ± 0.482
0.204MetGln: 0.204 ± 0.225
0.816MetArg: 0.816 ± 0.517
2.245MetSer: 2.245 ± 0.734
3.469MetThr: 3.469 ± 0.249
1.837MetVal: 1.837 ± 0.631
0.612MetTrp: 0.612 ± 0.34
1.429MetTyr: 1.429 ± 0.419
0.0MetXaa: 0.0 ± 0.0
Asn
2.449AsnAla: 2.449 ± 0.879
1.224AsnCys: 1.224 ± 0.519
1.633AsnAsp: 1.633 ± 0.495
2.245AsnGlu: 2.245 ± 0.576
1.633AsnPhe: 1.633 ± 0.285
2.245AsnGly: 2.245 ± 0.671
0.612AsnHis: 0.612 ± 0.308
3.265AsnIle: 3.265 ± 1.096
1.837AsnLys: 1.837 ± 1.07
5.714AsnLeu: 5.714 ± 0.627
1.429AsnMet: 1.429 ± 0.511
1.837AsnAsn: 1.837 ± 0.517
2.857AsnPro: 2.857 ± 0.9
2.857AsnGln: 2.857 ± 0.545
1.633AsnArg: 1.633 ± 0.631
2.857AsnSer: 2.857 ± 0.59
1.02AsnThr: 1.02 ± 0.562
2.653AsnVal: 2.653 ± 0.547
0.612AsnTrp: 0.612 ± 0.388
1.02AsnTyr: 1.02 ± 0.437
0.0AsnXaa: 0.0 ± 0.0
Pro
2.449ProAla: 2.449 ± 0.531
0.204ProCys: 0.204 ± 0.237
3.061ProAsp: 3.061 ± 0.898
2.857ProGlu: 2.857 ± 0.47
0.612ProPhe: 0.612 ± 0.232
3.673ProGly: 3.673 ± 1.096
0.816ProHis: 0.816 ± 0.325
5.102ProIle: 5.102 ± 0.782
2.245ProLys: 2.245 ± 0.537
4.49ProLeu: 4.49 ± 1.36
1.02ProMet: 1.02 ± 0.279
1.224ProAsn: 1.224 ± 0.217
3.061ProPro: 3.061 ± 0.74
1.837ProGln: 1.837 ± 0.944
2.857ProArg: 2.857 ± 0.666
4.286ProSer: 4.286 ± 1.295
2.653ProThr: 2.653 ± 0.71
2.449ProVal: 2.449 ± 0.497
0.408ProTrp: 0.408 ± 0.35
2.245ProTyr: 2.245 ± 0.757
0.0ProXaa: 0.0 ± 0.0
Gln
3.469GlnAla: 3.469 ± 1.344
1.224GlnCys: 1.224 ± 0.438
2.857GlnAsp: 2.857 ± 0.53
2.245GlnGlu: 2.245 ± 1.092
0.612GlnPhe: 0.612 ± 0.395
2.857GlnGly: 2.857 ± 0.495
0.408GlnHis: 0.408 ± 0.289
2.449GlnIle: 2.449 ± 0.724
1.224GlnLys: 1.224 ± 0.653
3.265GlnLeu: 3.265 ± 0.826
0.816GlnMet: 0.816 ± 0.264
2.041GlnAsn: 2.041 ± 0.485
1.429GlnPro: 1.429 ± 0.558
1.837GlnGln: 1.837 ± 0.554
2.449GlnArg: 2.449 ± 0.631
3.061GlnSer: 3.061 ± 1.268
1.02GlnThr: 1.02 ± 0.371
2.449GlnVal: 2.449 ± 0.501
0.408GlnTrp: 0.408 ± 0.258
0.612GlnTyr: 0.612 ± 0.531
0.0GlnXaa: 0.0 ± 0.0
Arg
4.49ArgAla: 4.49 ± 0.863
0.816ArgCys: 0.816 ± 0.309
3.061ArgAsp: 3.061 ± 0.701
3.469ArgGlu: 3.469 ± 0.853
2.041ArgPhe: 2.041 ± 0.565
4.082ArgGly: 4.082 ± 0.744
1.837ArgHis: 1.837 ± 0.398
3.469ArgIle: 3.469 ± 0.964
3.061ArgLys: 3.061 ± 0.866
8.163ArgLeu: 8.163 ± 1.062
1.429ArgMet: 1.429 ± 0.42
1.633ArgAsn: 1.633 ± 0.435
1.837ArgPro: 1.837 ± 0.547
1.837ArgGln: 1.837 ± 0.44
4.49ArgArg: 4.49 ± 1.084
5.918ArgSer: 5.918 ± 0.971
2.245ArgThr: 2.245 ± 0.797
3.469ArgVal: 3.469 ± 0.565
0.204ArgTrp: 0.204 ± 0.215
2.041ArgTyr: 2.041 ± 0.726
0.0ArgXaa: 0.0 ± 0.0
Ser
4.49SerAla: 4.49 ± 1.173
1.633SerCys: 1.633 ± 0.639
4.49SerAsp: 4.49 ± 1.119
3.469SerGlu: 3.469 ± 0.993
3.061SerPhe: 3.061 ± 0.691
7.551SerGly: 7.551 ± 1.314
2.041SerHis: 2.041 ± 0.656
5.51SerIle: 5.51 ± 0.756
3.673SerLys: 3.673 ± 0.635
8.163SerLeu: 8.163 ± 0.593
2.449SerMet: 2.449 ± 0.587
3.469SerAsn: 3.469 ± 0.942
3.061SerPro: 3.061 ± 0.747
3.469SerGln: 3.469 ± 0.886
7.551SerArg: 7.551 ± 1.233
7.347SerSer: 7.347 ± 0.88
5.714SerThr: 5.714 ± 0.691
3.673SerVal: 3.673 ± 0.996
1.224SerTrp: 1.224 ± 0.444
3.061SerTyr: 3.061 ± 1.308
0.0SerXaa: 0.0 ± 0.0
Thr
3.673ThrAla: 3.673 ± 1.02
1.224ThrCys: 1.224 ± 0.384
3.265ThrAsp: 3.265 ± 0.722
3.265ThrGlu: 3.265 ± 0.869
1.02ThrPhe: 1.02 ± 0.286
4.082ThrGly: 4.082 ± 0.68
1.02ThrHis: 1.02 ± 0.375
4.082ThrIle: 4.082 ± 0.88
1.224ThrLys: 1.224 ± 0.578
5.918ThrLeu: 5.918 ± 1.295
1.429ThrMet: 1.429 ± 0.46
3.061ThrAsn: 3.061 ± 0.807
3.061ThrPro: 3.061 ± 0.924
1.633ThrGln: 1.633 ± 0.48
3.469ThrArg: 3.469 ± 0.595
3.878ThrSer: 3.878 ± 0.422
3.878ThrThr: 3.878 ± 0.769
2.653ThrVal: 2.653 ± 0.613
1.02ThrTrp: 1.02 ± 0.403
2.653ThrTyr: 2.653 ± 0.521
0.0ThrXaa: 0.0 ± 0.0
Val
2.857ValAla: 2.857 ± 0.416
1.02ValCys: 1.02 ± 0.478
2.245ValAsp: 2.245 ± 0.544
4.286ValGlu: 4.286 ± 0.585
2.245ValPhe: 2.245 ± 0.841
3.878ValGly: 3.878 ± 0.644
1.224ValHis: 1.224 ± 0.424
6.122ValIle: 6.122 ± 1.168
2.857ValLys: 2.857 ± 0.691
6.531ValLeu: 6.531 ± 0.971
0.816ValMet: 0.816 ± 0.236
2.245ValAsn: 2.245 ± 0.479
4.286ValPro: 4.286 ± 0.857
2.245ValGln: 2.245 ± 0.644
3.673ValArg: 3.673 ± 0.919
5.918ValSer: 5.918 ± 1.166
3.265ValThr: 3.265 ± 0.766
2.653ValVal: 2.653 ± 1.028
0.204ValTrp: 0.204 ± 0.225
3.265ValTyr: 3.265 ± 0.536
0.0ValXaa: 0.0 ± 0.0
Trp
1.224TrpAla: 1.224 ± 0.464
0.408TrpCys: 0.408 ± 0.451
0.612TrpAsp: 0.612 ± 0.325
0.204TrpGlu: 0.204 ± 0.291
1.02TrpPhe: 1.02 ± 0.4
0.612TrpGly: 0.612 ± 0.376
0.204TrpHis: 0.204 ± 0.129
0.612TrpIle: 0.612 ± 0.422
0.612TrpLys: 0.612 ± 0.232
0.816TrpLeu: 0.816 ± 0.282
0.0TrpMet: 0.0 ± 0.0
0.612TrpAsn: 0.612 ± 0.34
0.612TrpPro: 0.612 ± 0.34
0.408TrpGln: 0.408 ± 0.344
0.612TrpArg: 0.612 ± 0.575
0.816TrpSer: 0.816 ± 0.264
0.408TrpThr: 0.408 ± 0.221
0.816TrpVal: 0.816 ± 0.282
0.0TrpTrp: 0.0 ± 0.0
0.408TrpTyr: 0.408 ± 0.228
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.816TyrAla: 0.816 ± 0.286
1.224TyrCys: 1.224 ± 0.394
2.653TyrAsp: 2.653 ± 0.741
1.224TyrGlu: 1.224 ± 0.775
1.429TyrPhe: 1.429 ± 0.632
1.224TyrGly: 1.224 ± 0.464
0.612TyrHis: 0.612 ± 0.388
1.224TyrIle: 1.224 ± 0.687
1.837TyrLys: 1.837 ± 0.55
4.49TyrLeu: 4.49 ± 1.146
1.429TyrMet: 1.429 ± 0.55
1.02TyrAsn: 1.02 ± 0.297
3.061TyrPro: 3.061 ± 0.636
1.224TyrGln: 1.224 ± 0.353
1.224TyrArg: 1.224 ± 0.286
3.673TyrSer: 3.673 ± 1.228
2.041TyrThr: 2.041 ± 0.569
1.837TyrVal: 1.837 ± 0.576
0.204TyrTrp: 0.204 ± 0.225
1.429TyrTyr: 1.429 ± 0.502
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4901 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski