Amino acid dipepetide frequency for Durania virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.312AlaAla: 3.312 ± 2.082
1.019AlaCys: 1.019 ± 0.22
3.057AlaAsp: 3.057 ± 0.987
3.057AlaGlu: 3.057 ± 0.665
0.764AlaPhe: 0.764 ± 0.292
3.822AlaGly: 3.822 ± 1.333
2.293AlaHis: 2.293 ± 0.625
5.605AlaIle: 5.605 ± 0.868
3.822AlaLys: 3.822 ± 0.881
5.096AlaLeu: 5.096 ± 1.379
2.803AlaMet: 2.803 ± 0.449
1.019AlaAsn: 1.019 ± 0.22
2.803AlaPro: 2.803 ± 1.274
0.764AlaGln: 0.764 ± 0.417
2.038AlaArg: 2.038 ± 0.657
4.586AlaSer: 4.586 ± 0.616
2.548AlaThr: 2.548 ± 0.36
2.038AlaVal: 2.038 ± 1.168
0.764AlaTrp: 0.764 ± 0.417
2.038AlaTyr: 2.038 ± 0.303
0.0AlaXaa: 0.0 ± 0.0
Cys
0.255CysAla: 0.255 ± 0.148
1.019CysCys: 1.019 ± 0.592
1.529CysAsp: 1.529 ± 0.33
2.548CysGlu: 2.548 ± 0.583
1.529CysPhe: 1.529 ± 0.896
0.764CysGly: 0.764 ± 0.611
1.019CysHis: 1.019 ± 0.492
1.529CysIle: 1.529 ± 0.33
2.548CysLys: 2.548 ± 0.36
1.783CysLeu: 1.783 ± 1.099
1.019CysMet: 1.019 ± 0.552
1.019CysAsn: 1.019 ± 0.22
0.51CysPro: 0.51 ± 0.11
1.529CysGln: 1.529 ± 0.719
1.783CysArg: 1.783 ± 0.329
4.841CysSer: 4.841 ± 2.257
1.274CysThr: 1.274 ± 0.235
1.274CysVal: 1.274 ± 0.58
0.0CysTrp: 0.0 ± 0.0
1.019CysTyr: 1.019 ± 0.492
0.0CysXaa: 0.0 ± 0.0
Asp
2.803AspAla: 2.803 ± 2.072
1.529AspCys: 1.529 ± 0.33
5.86AspAsp: 5.86 ± 0.586
4.076AspGlu: 4.076 ± 0.98
2.548AspPhe: 2.548 ± 0.99
3.822AspGly: 3.822 ± 0.751
0.764AspHis: 0.764 ± 0.163
3.312AspIle: 3.312 ± 0.728
2.803AspLys: 2.803 ± 0.468
5.35AspLeu: 5.35 ± 1.347
2.038AspMet: 2.038 ± 0.582
2.548AspAsn: 2.548 ± 0.607
2.803AspPro: 2.803 ± 0.687
2.293AspGln: 2.293 ± 0.556
2.293AspArg: 2.293 ± 0.775
6.624AspSer: 6.624 ± 1.082
2.293AspThr: 2.293 ± 0.331
3.312AspVal: 3.312 ± 0.624
0.764AspTrp: 0.764 ± 0.163
1.783AspTyr: 1.783 ± 0.496
0.0AspXaa: 0.0 ± 0.0
Glu
3.822GluAla: 3.822 ± 1.042
1.783GluCys: 1.783 ± 0.496
6.624GluAsp: 6.624 ± 0.742
5.35GluGlu: 5.35 ± 0.584
4.331GluPhe: 4.331 ± 1.111
4.076GluGly: 4.076 ± 0.539
1.783GluHis: 1.783 ± 0.276
4.841GluIle: 4.841 ± 0.603
2.803GluLys: 2.803 ± 0.814
7.643GluLeu: 7.643 ± 1.03
2.038GluMet: 2.038 ± 0.623
2.548GluAsn: 2.548 ± 0.873
0.764GluPro: 0.764 ± 0.163
1.019GluGln: 1.019 ± 0.22
3.057GluArg: 3.057 ± 0.872
5.35GluSer: 5.35 ± 1.036
2.038GluThr: 2.038 ± 0.383
5.605GluVal: 5.605 ± 0.316
0.255GluTrp: 0.255 ± 0.148
0.51GluTyr: 0.51 ± 0.296
0.0GluXaa: 0.0 ± 0.0
Phe
2.548PheAla: 2.548 ± 0.685
0.51PheCys: 0.51 ± 0.11
2.803PheAsp: 2.803 ± 0.808
2.803PheGlu: 2.803 ± 0.509
2.293PhePhe: 2.293 ± 0.288
3.057PheGly: 3.057 ± 0.571
0.764PheHis: 0.764 ± 0.163
3.057PheIle: 3.057 ± 0.437
3.057PheLys: 3.057 ± 0.57
3.822PheLeu: 3.822 ± 1.014
1.274PheMet: 1.274 ± 0.316
1.274PheAsn: 1.274 ± 0.305
2.548PhePro: 2.548 ± 0.99
0.764PheGln: 0.764 ± 0.611
3.312PheArg: 3.312 ± 0.902
5.605PheSer: 5.605 ± 0.647
2.548PheThr: 2.548 ± 0.608
4.076PheVal: 4.076 ± 0.629
0.51PheTrp: 0.51 ± 0.296
0.51PheTyr: 0.51 ± 0.331
0.0PheXaa: 0.0 ± 0.0
Gly
2.293GlyAla: 2.293 ± 0.722
1.019GlyCys: 1.019 ± 0.22
2.548GlyAsp: 2.548 ± 0.583
2.548GlyGlu: 2.548 ± 0.324
4.841GlyPhe: 4.841 ± 0.739
3.567GlyGly: 3.567 ± 0.822
1.783GlyHis: 1.783 ± 0.509
3.567GlyIle: 3.567 ± 0.452
4.331GlyLys: 4.331 ± 0.639
5.096GlyLeu: 5.096 ± 1.232
1.529GlyMet: 1.529 ± 0.547
2.038GlyAsn: 2.038 ± 1.055
2.293GlyPro: 2.293 ± 0.331
1.019GlyGln: 1.019 ± 0.421
2.548GlyArg: 2.548 ± 1.243
7.134GlySer: 7.134 ± 1.318
3.822GlyThr: 3.822 ± 0.418
4.586GlyVal: 4.586 ± 0.495
1.274GlyTrp: 1.274 ± 0.614
1.529GlyTyr: 1.529 ± 0.639
0.0GlyXaa: 0.0 ± 0.0
His
0.764HisAla: 0.764 ± 0.292
1.019HisCys: 1.019 ± 0.492
1.529HisAsp: 1.529 ± 0.455
1.019HisGlu: 1.019 ± 0.275
1.274HisPhe: 1.274 ± 0.305
1.274HisGly: 1.274 ± 0.74
0.51HisHis: 0.51 ± 0.11
1.783HisIle: 1.783 ± 0.496
1.783HisLys: 1.783 ± 1.359
2.293HisLeu: 2.293 ± 0.489
0.255HisMet: 0.255 ± 0.204
1.274HisAsn: 1.274 ± 0.682
1.274HisPro: 1.274 ± 0.568
0.51HisGln: 0.51 ± 0.296
2.038HisArg: 2.038 ± 0.639
2.293HisSer: 2.293 ± 0.405
1.529HisThr: 1.529 ± 0.76
2.038HisVal: 2.038 ± 0.657
0.255HisTrp: 0.255 ± 0.204
1.274HisTyr: 1.274 ± 0.235
0.0HisXaa: 0.0 ± 0.0
Ile
2.803IleAla: 2.803 ± 0.301
2.038IleCys: 2.038 ± 0.284
4.076IleAsp: 4.076 ± 0.848
4.331IleGlu: 4.331 ± 1.255
2.548IlePhe: 2.548 ± 0.607
4.331IleGly: 4.331 ± 0.977
1.019IleHis: 1.019 ± 0.22
5.35IleIle: 5.35 ± 1.228
3.822IleLys: 3.822 ± 0.5
6.624IleLeu: 6.624 ± 0.693
1.783IleMet: 1.783 ± 0.701
2.038IleAsn: 2.038 ± 0.516
2.293IlePro: 2.293 ± 0.625
1.783IleGln: 1.783 ± 0.329
4.841IleArg: 4.841 ± 0.695
5.605IleSer: 5.605 ± 0.937
3.822IleThr: 3.822 ± 0.852
3.057IleVal: 3.057 ± 1.072
0.51IleTrp: 0.51 ± 0.296
2.038IleTyr: 2.038 ± 0.582
0.0IleXaa: 0.0 ± 0.0
Lys
4.331LysAla: 4.331 ± 0.639
3.057LysCys: 3.057 ± 1.169
2.548LysAsp: 2.548 ± 0.607
3.822LysGlu: 3.822 ± 0.62
3.312LysPhe: 3.312 ± 0.816
1.529LysGly: 1.529 ± 0.326
1.019LysHis: 1.019 ± 0.421
4.076LysIle: 4.076 ± 0.563
5.35LysLys: 5.35 ± 0.353
4.076LysLeu: 4.076 ± 0.779
3.567LysMet: 3.567 ± 1.741
3.057LysAsn: 3.057 ± 0.594
1.783LysPro: 1.783 ± 0.448
1.783LysGln: 1.783 ± 0.378
2.803LysArg: 2.803 ± 1.234
6.115LysSer: 6.115 ± 0.981
3.567LysThr: 3.567 ± 0.556
4.586LysVal: 4.586 ± 0.969
1.529LysTrp: 1.529 ± 0.393
2.038LysTyr: 2.038 ± 0.639
0.0LysXaa: 0.0 ± 0.0
Leu
5.096LeuAla: 5.096 ± 1.978
2.293LeuCys: 2.293 ± 0.431
5.605LeuAsp: 5.605 ± 1.654
6.115LeuGlu: 6.115 ± 1.169
5.35LeuPhe: 5.35 ± 0.224
4.331LeuGly: 4.331 ± 0.891
3.057LeuHis: 3.057 ± 0.911
5.35LeuIle: 5.35 ± 1.589
5.86LeuLys: 5.86 ± 0.825
7.134LeuLeu: 7.134 ± 0.544
2.293LeuMet: 2.293 ± 0.326
1.274LeuAsn: 1.274 ± 0.305
3.567LeuPro: 3.567 ± 1.203
4.076LeuGln: 4.076 ± 1.096
6.624LeuArg: 6.624 ± 0.848
8.662LeuSer: 8.662 ± 1.114
3.567LeuThr: 3.567 ± 0.902
6.115LeuVal: 6.115 ± 0.981
0.0LeuTrp: 0.0 ± 0.0
1.783LeuTyr: 1.783 ± 0.276
0.0LeuXaa: 0.0 ± 0.0
Met
1.529MetAla: 1.529 ± 0.493
0.51MetCys: 0.51 ± 0.11
1.783MetAsp: 1.783 ± 0.321
2.548MetGlu: 2.548 ± 0.975
1.019MetPhe: 1.019 ± 0.592
2.548MetGly: 2.548 ± 1.123
1.274MetHis: 1.274 ± 0.568
2.038MetIle: 2.038 ± 1.042
2.803MetLys: 2.803 ± 0.679
2.803MetLeu: 2.803 ± 0.954
1.529MetMet: 1.529 ± 0.722
0.764MetAsn: 0.764 ± 0.444
0.764MetPro: 0.764 ± 0.319
2.293MetGln: 2.293 ± 0.477
1.783MetArg: 1.783 ± 0.448
2.548MetSer: 2.548 ± 0.565
1.783MetThr: 1.783 ± 0.615
1.274MetVal: 1.274 ± 0.432
0.0MetTrp: 0.0 ± 0.0
0.255MetTyr: 0.255 ± 0.148
0.0MetXaa: 0.0 ± 0.0
Asn
1.783AsnAla: 1.783 ± 0.986
0.764AsnCys: 0.764 ± 0.547
1.019AsnAsp: 1.019 ± 0.492
2.293AsnGlu: 2.293 ± 0.405
2.548AsnPhe: 2.548 ± 0.711
2.293AsnGly: 2.293 ± 0.856
1.019AsnHis: 1.019 ± 0.592
1.529AsnIle: 1.529 ± 0.719
2.293AsnLys: 2.293 ± 0.331
3.822AsnLeu: 3.822 ± 0.521
0.255AsnMet: 0.255 ± 0.148
1.019AsnAsn: 1.019 ± 0.275
3.312AsnPro: 3.312 ± 0.747
1.529AsnGln: 1.529 ± 0.687
0.255AsnArg: 0.255 ± 0.204
3.312AsnSer: 3.312 ± 0.819
2.548AsnThr: 2.548 ± 0.551
2.293AsnVal: 2.293 ± 1.185
0.255AsnTrp: 0.255 ± 0.148
0.764AsnTyr: 0.764 ± 0.163
0.0AsnXaa: 0.0 ± 0.0
Pro
2.803ProAla: 2.803 ± 0.557
0.255ProCys: 0.255 ± 0.204
3.312ProAsp: 3.312 ± 0.968
3.822ProGlu: 3.822 ± 1.194
2.038ProPhe: 2.038 ± 0.626
2.548ProGly: 2.548 ± 0.768
1.274ProHis: 1.274 ± 0.482
1.783ProIle: 1.783 ± 0.496
2.038ProLys: 2.038 ± 0.39
3.822ProLeu: 3.822 ± 0.858
0.51ProMet: 0.51 ± 0.444
2.038ProAsn: 2.038 ± 0.55
0.51ProPro: 0.51 ± 0.444
2.293ProGln: 2.293 ± 0.288
2.038ProArg: 2.038 ± 0.818
3.312ProSer: 3.312 ± 1.17
1.274ProThr: 1.274 ± 0.235
2.548ProVal: 2.548 ± 0.803
1.019ProTrp: 1.019 ± 0.291
0.255ProTyr: 0.255 ± 0.148
0.0ProXaa: 0.0 ± 0.0
Gln
2.293GlnAla: 2.293 ± 1.005
1.019GlnCys: 1.019 ± 0.421
1.274GlnAsp: 1.274 ± 0.382
1.529GlnGlu: 1.529 ± 0.444
1.019GlnPhe: 1.019 ± 0.521
2.548GlnGly: 2.548 ± 0.742
0.51GlnHis: 0.51 ± 0.296
3.312GlnIle: 3.312 ± 0.486
2.038GlnLys: 2.038 ± 0.8
1.529GlnLeu: 1.529 ± 0.32
1.019GlnMet: 1.019 ± 0.426
1.274GlnAsn: 1.274 ± 0.392
2.293GlnPro: 2.293 ± 0.349
1.274GlnGln: 1.274 ± 0.612
1.783GlnArg: 1.783 ± 0.642
2.803GlnSer: 2.803 ± 0.239
1.019GlnThr: 1.019 ± 0.291
0.764GlnVal: 0.764 ± 0.163
0.255GlnTrp: 0.255 ± 0.204
1.274GlnTyr: 1.274 ± 0.392
0.0GlnXaa: 0.0 ± 0.0
Arg
3.822ArgAla: 3.822 ± 1.342
1.783ArgCys: 1.783 ± 1.28
3.567ArgAsp: 3.567 ± 0.377
4.331ArgGlu: 4.331 ± 1.077
1.529ArgPhe: 1.529 ± 0.577
4.586ArgGly: 4.586 ± 1.012
0.255ArgHis: 0.255 ± 0.148
4.076ArgIle: 4.076 ± 1.152
3.312ArgLys: 3.312 ± 0.747
3.567ArgLeu: 3.567 ± 0.556
1.529ArgMet: 1.529 ± 0.598
2.038ArgAsn: 2.038 ± 0.819
1.783ArgPro: 1.783 ± 0.631
1.019ArgGln: 1.019 ± 0.22
1.783ArgArg: 1.783 ± 0.642
4.841ArgSer: 4.841 ± 1.586
3.057ArgThr: 3.057 ± 0.562
4.586ArgVal: 4.586 ± 1.014
1.529ArgTrp: 1.529 ± 0.257
2.293ArgTyr: 2.293 ± 0.291
0.0ArgXaa: 0.0 ± 0.0
Ser
4.841SerAla: 4.841 ± 0.938
3.312SerCys: 3.312 ± 1.676
5.86SerAsp: 5.86 ± 0.839
7.898SerGlu: 7.898 ± 1.375
3.822SerPhe: 3.822 ± 1.51
5.096SerGly: 5.096 ± 0.732
3.822SerHis: 3.822 ± 0.941
5.35SerIle: 5.35 ± 1.512
5.605SerLys: 5.605 ± 0.689
9.682SerLeu: 9.682 ± 0.839
2.548SerMet: 2.548 ± 0.61
2.293SerAsn: 2.293 ± 0.288
4.331SerPro: 4.331 ± 0.685
1.274SerGln: 1.274 ± 0.612
6.624SerArg: 6.624 ± 0.544
11.21SerSer: 11.21 ± 1.846
4.586SerThr: 4.586 ± 0.577
5.86SerVal: 5.86 ± 0.826
1.529SerTrp: 1.529 ± 0.795
3.312SerTyr: 3.312 ± 0.728
0.0SerXaa: 0.0 ± 0.0
Thr
1.529ThrAla: 1.529 ± 0.326
1.529ThrCys: 1.529 ± 0.488
2.293ThrAsp: 2.293 ± 0.288
4.076ThrGlu: 4.076 ± 1.164
2.038ThrPhe: 2.038 ± 0.441
5.096ThrGly: 5.096 ± 1.259
0.51ThrHis: 0.51 ± 0.296
1.783ThrIle: 1.783 ± 0.496
3.057ThrLys: 3.057 ± 0.562
5.86ThrLeu: 5.86 ± 0.698
1.274ThrMet: 1.274 ± 0.432
2.548ThrAsn: 2.548 ± 0.888
2.548ThrPro: 2.548 ± 0.36
2.038ThrGln: 2.038 ± 0.303
3.312ThrArg: 3.312 ± 0.499
4.586ThrSer: 4.586 ± 0.948
2.293ThrThr: 2.293 ± 0.687
3.057ThrVal: 3.057 ± 0.17
0.0ThrTrp: 0.0 ± 0.0
0.51ThrTyr: 0.51 ± 0.331
0.0ThrXaa: 0.0 ± 0.0
Val
3.822ValAla: 3.822 ± 1.997
2.548ValCys: 2.548 ± 0.471
3.567ValAsp: 3.567 ± 0.822
2.293ValGlu: 2.293 ± 0.291
2.803ValPhe: 2.803 ± 0.71
2.293ValGly: 2.293 ± 0.489
2.038ValHis: 2.038 ± 0.511
2.803ValIle: 2.803 ± 1.02
4.841ValLys: 4.841 ± 0.952
4.331ValLeu: 4.331 ± 0.649
3.567ValMet: 3.567 ± 0.867
3.312ValAsn: 3.312 ± 1.715
1.274ValPro: 1.274 ± 0.305
2.038ValGln: 2.038 ± 0.303
4.586ValArg: 4.586 ± 1.101
6.624ValSer: 6.624 ± 0.835
3.312ValThr: 3.312 ± 0.929
4.586ValVal: 4.586 ± 0.989
1.019ValTrp: 1.019 ± 0.592
1.783ValTyr: 1.783 ± 0.276
0.0ValXaa: 0.0 ± 0.0
Trp
1.019TrpAla: 1.019 ± 0.22
0.255TrpCys: 0.255 ± 0.148
0.0TrpAsp: 0.0 ± 0.0
0.51TrpGlu: 0.51 ± 0.296
0.51TrpPhe: 0.51 ± 0.11
1.019TrpGly: 1.019 ± 0.275
0.255TrpHis: 0.255 ± 0.204
1.274TrpIle: 1.274 ± 0.305
0.255TrpLys: 0.255 ± 0.148
1.783TrpLeu: 1.783 ± 0.276
0.255TrpMet: 0.255 ± 0.204
0.51TrpAsn: 0.51 ± 0.11
0.51TrpPro: 0.51 ± 0.331
0.255TrpGln: 0.255 ± 0.475
0.255TrpArg: 0.255 ± 0.148
0.764TrpSer: 0.764 ± 0.163
1.783TrpThr: 1.783 ± 0.541
0.764TrpVal: 0.764 ± 0.417
0.255TrpTrp: 0.255 ± 0.148
0.255TrpTyr: 0.255 ± 0.148
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.783TyrAla: 1.783 ± 0.329
1.529TyrCys: 1.529 ± 0.829
0.764TyrAsp: 0.764 ± 0.163
1.274TyrGlu: 1.274 ± 0.694
1.019TyrPhe: 1.019 ± 0.451
0.764TyrGly: 0.764 ± 0.444
1.019TyrHis: 1.019 ± 0.291
2.293TyrIle: 2.293 ± 0.775
1.529TyrLys: 1.529 ± 0.326
2.293TyrLeu: 2.293 ± 0.477
0.51TyrMet: 0.51 ± 0.331
1.019TyrAsn: 1.019 ± 0.291
1.529TyrPro: 1.529 ± 0.455
1.274TyrGln: 1.274 ± 0.837
1.529TyrArg: 1.529 ± 0.577
2.038TyrSer: 2.038 ± 0.441
1.274TyrThr: 1.274 ± 0.235
1.019TyrVal: 1.019 ± 0.451
0.764TyrTrp: 0.764 ± 0.292
0.51TyrTyr: 0.51 ± 0.296
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3926 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski