Amino acid dipepetide frequency for Baminivirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.58AlaAla: 5.58 ± 2.01
1.116AlaCys: 1.116 ± 0.979
5.58AlaAsp: 5.58 ± 3.444
3.348AlaGlu: 3.348 ± 2.938
1.116AlaPhe: 1.116 ± 0.689
6.696AlaGly: 6.696 ± 3.151
1.116AlaHis: 1.116 ± 0.689
1.116AlaIle: 1.116 ± 0.689
5.58AlaLys: 5.58 ± 2.01
6.696AlaLeu: 6.696 ± 1.552
1.116AlaMet: 1.116 ± 1.296
4.464AlaAsn: 4.464 ± 1.359
3.348AlaPro: 3.348 ± 0.776
3.348AlaGln: 3.348 ± 0.776
7.812AlaArg: 7.812 ± 1.295
3.348AlaSer: 3.348 ± 0.776
6.696AlaThr: 6.696 ± 2.68
3.348AlaVal: 3.348 ± 1.434
2.232AlaTrp: 2.232 ± 1.959
1.116AlaTyr: 1.116 ± 0.689
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.116CysAsp: 1.116 ± 0.979
1.116CysGlu: 1.116 ± 0.979
1.116CysPhe: 1.116 ± 0.689
0.0CysGly: 0.0 ± 0.0
1.116CysHis: 1.116 ± 0.979
0.0CysIle: 0.0 ± 0.0
1.116CysLys: 1.116 ± 0.689
1.116CysLeu: 1.116 ± 0.689
0.0CysMet: 0.0 ± 0.0
1.116CysAsn: 1.116 ± 0.979
1.116CysPro: 1.116 ± 2.043
1.116CysGln: 1.116 ± 0.979
0.0CysArg: 0.0 ± 0.0
1.116CysSer: 1.116 ± 0.979
0.0CysThr: 0.0 ± 0.0
1.116CysVal: 1.116 ± 2.043
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.464AspAla: 4.464 ± 1.359
0.0AspCys: 0.0 ± 0.0
5.58AspAsp: 5.58 ± 1.159
1.116AspGlu: 1.116 ± 0.979
2.232AspPhe: 2.232 ± 2.146
5.58AspGly: 5.58 ± 1.352
2.232AspHis: 2.232 ± 1.378
3.348AspIle: 3.348 ± 0.776
2.232AspLys: 2.232 ± 1.378
7.812AspLeu: 7.812 ± 2.932
3.348AspMet: 3.348 ± 0.776
0.0AspAsn: 0.0 ± 0.0
1.116AspPro: 1.116 ± 2.043
0.0AspGln: 0.0 ± 0.0
3.348AspArg: 3.348 ± 1.434
2.232AspSer: 2.232 ± 0.553
7.812AspThr: 7.812 ± 2.103
2.232AspVal: 2.232 ± 0.553
2.232AspTrp: 2.232 ± 1.959
1.116AspTyr: 1.116 ± 0.979
0.0AspXaa: 0.0 ± 0.0
Glu
2.232GluAla: 2.232 ± 1.378
1.116GluCys: 1.116 ± 0.979
0.0GluAsp: 0.0 ± 0.0
1.116GluGlu: 1.116 ± 0.689
3.348GluPhe: 3.348 ± 1.653
3.348GluGly: 3.348 ± 2.938
0.0GluHis: 0.0 ± 0.0
1.116GluIle: 1.116 ± 0.979
2.232GluLys: 2.232 ± 1.378
2.232GluLeu: 2.232 ± 1.959
1.116GluMet: 1.116 ± 0.689
0.0GluAsn: 0.0 ± 0.0
3.348GluPro: 3.348 ± 2.938
3.348GluGln: 3.348 ± 1.434
2.232GluArg: 2.232 ± 1.959
2.232GluSer: 2.232 ± 2.146
1.116GluThr: 1.116 ± 0.689
2.232GluVal: 2.232 ± 1.959
3.348GluTrp: 3.348 ± 1.434
5.58GluTyr: 5.58 ± 1.159
0.0GluXaa: 0.0 ± 0.0
Phe
5.58PheAla: 5.58 ± 1.94
0.0PheCys: 0.0 ± 0.0
3.348PheAsp: 3.348 ± 2.938
1.116PheGlu: 1.116 ± 0.689
4.464PhePhe: 4.464 ± 1.107
2.232PheGly: 2.232 ± 2.146
3.348PheHis: 3.348 ± 0.776
2.232PheIle: 2.232 ± 2.146
1.116PheLys: 1.116 ± 0.689
4.464PheLeu: 4.464 ± 4.292
0.0PheMet: 0.0 ± 0.0
2.232PheAsn: 2.232 ± 0.553
1.116PhePro: 1.116 ± 0.689
1.116PheGln: 1.116 ± 0.689
1.116PheArg: 1.116 ± 0.979
2.232PheSer: 2.232 ± 1.378
6.696PheThr: 6.696 ± 3.305
2.232PheVal: 2.232 ± 0.553
0.0PheTrp: 0.0 ± 0.0
3.348PheTyr: 3.348 ± 1.653
0.0PheXaa: 0.0 ± 0.0
Gly
11.161GlyAla: 11.161 ± 0.781
2.232GlyCys: 2.232 ± 0.553
4.464GlyAsp: 4.464 ± 2.186
3.348GlyGlu: 3.348 ± 1.434
2.232GlyPhe: 2.232 ± 2.146
7.812GlyGly: 7.812 ± 4.043
0.0GlyHis: 0.0 ± 0.0
1.116GlyIle: 1.116 ± 0.689
3.348GlyLys: 3.348 ± 1.434
5.58GlyLeu: 5.58 ± 2.623
0.0GlyMet: 0.0 ± 0.0
1.116GlyAsn: 1.116 ± 0.979
2.232GlyPro: 2.232 ± 2.146
1.116GlyGln: 1.116 ± 0.689
7.812GlyArg: 7.812 ± 1.295
5.58GlySer: 5.58 ± 3.444
2.232GlyThr: 2.232 ± 1.378
6.696GlyVal: 6.696 ± 2.68
2.232GlyTrp: 2.232 ± 1.852
2.232GlyTyr: 2.232 ± 1.852
0.0GlyXaa: 0.0 ± 0.0
His
1.116HisAla: 1.116 ± 0.689
0.0HisCys: 0.0 ± 0.0
4.464HisAsp: 4.464 ± 1.359
1.116HisGlu: 1.116 ± 0.689
1.116HisPhe: 1.116 ± 2.043
1.116HisGly: 1.116 ± 0.689
0.0HisHis: 0.0 ± 0.0
5.58HisIle: 5.58 ± 2.01
2.232HisLys: 2.232 ± 0.553
2.232HisLeu: 2.232 ± 0.553
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.232HisPro: 2.232 ± 0.553
1.116HisGln: 1.116 ± 0.979
0.0HisArg: 0.0 ± 0.0
2.232HisSer: 2.232 ± 1.378
4.464HisThr: 4.464 ± 1.359
3.348HisVal: 3.348 ± 2.637
0.0HisTrp: 0.0 ± 0.0
2.232HisTyr: 2.232 ± 1.378
0.0HisXaa: 0.0 ± 0.0
Ile
3.348IleAla: 3.348 ± 1.653
0.0IleCys: 0.0 ± 0.0
3.348IleAsp: 3.348 ± 2.066
0.0IleGlu: 0.0 ± 0.0
3.348IlePhe: 3.348 ± 1.653
6.696IleGly: 6.696 ± 1.673
1.116IleHis: 1.116 ± 0.689
1.116IleIle: 1.116 ± 0.689
3.348IleLys: 3.348 ± 0.776
5.58IleLeu: 5.58 ± 4.896
0.0IleMet: 0.0 ± 0.0
1.116IleAsn: 1.116 ± 0.689
1.116IlePro: 1.116 ± 0.979
2.232IleGln: 2.232 ± 1.378
4.464IleArg: 4.464 ± 2.186
2.232IleSer: 2.232 ± 0.553
1.116IleThr: 1.116 ± 0.689
1.116IleVal: 1.116 ± 0.979
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
3.348LysGlu: 3.348 ± 1.905
2.232LysPhe: 2.232 ± 0.553
4.464LysGly: 4.464 ± 1.359
6.696LysHis: 6.696 ± 1.552
3.348LysIle: 3.348 ± 2.066
4.464LysLys: 4.464 ± 1.359
0.0LysLeu: 0.0 ± 0.0
1.116LysMet: 1.116 ± 0.689
2.232LysAsn: 2.232 ± 0.553
3.348LysPro: 3.348 ± 1.434
3.348LysGln: 3.348 ± 0.776
2.232LysArg: 2.232 ± 1.378
6.696LysSer: 6.696 ± 1.552
6.696LysThr: 6.696 ± 1.66
1.116LysVal: 1.116 ± 0.689
1.116LysTrp: 1.116 ± 0.689
2.232LysTyr: 2.232 ± 1.378
0.0LysXaa: 0.0 ± 0.0
Leu
5.58LeuAla: 5.58 ± 2.01
1.116LeuCys: 1.116 ± 2.043
4.464LeuAsp: 4.464 ± 2.392
8.929LeuGlu: 8.929 ± 3.367
1.116LeuPhe: 1.116 ± 0.979
12.277LeuGly: 12.277 ± 4.289
2.232LeuHis: 2.232 ± 0.553
0.0LeuIle: 0.0 ± 0.0
4.464LeuLys: 4.464 ± 1.344
2.232LeuLeu: 2.232 ± 0.553
2.232LeuMet: 2.232 ± 1.228
1.116LeuAsn: 1.116 ± 0.979
4.464LeuPro: 4.464 ± 1.988
3.348LeuGln: 3.348 ± 2.938
6.696LeuArg: 6.696 ± 4.1
6.696LeuSer: 6.696 ± 3.81
5.58LeuThr: 5.58 ± 1.159
4.464LeuVal: 4.464 ± 1.107
1.116LeuTrp: 1.116 ± 0.979
5.58LeuTyr: 5.58 ± 2.01
0.0LeuXaa: 0.0 ± 0.0
Met
2.232MetAla: 2.232 ± 0.553
0.0MetCys: 0.0 ± 0.0
1.116MetAsp: 1.116 ± 0.689
1.116MetGlu: 1.116 ± 0.979
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.116MetLys: 1.116 ± 0.689
2.232MetLeu: 2.232 ± 1.378
0.0MetMet: 0.0 ± 0.0
1.116MetAsn: 1.116 ± 2.043
1.116MetPro: 1.116 ± 0.689
0.0MetGln: 0.0 ± 0.0
3.348MetArg: 3.348 ± 1.905
2.232MetSer: 2.232 ± 1.378
3.348MetThr: 3.348 ± 0.776
0.0MetVal: 0.0 ± 0.0
1.116MetTrp: 1.116 ± 0.689
2.232MetTyr: 2.232 ± 1.959
0.0MetXaa: 0.0 ± 0.0
Asn
2.232AsnAla: 2.232 ± 0.553
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
3.348AsnGlu: 3.348 ± 1.653
1.116AsnPhe: 1.116 ± 0.689
1.116AsnGly: 1.116 ± 0.689
0.0AsnHis: 0.0 ± 0.0
2.232AsnIle: 2.232 ± 1.959
4.464AsnLys: 4.464 ± 1.359
3.348AsnLeu: 3.348 ± 1.434
3.348AsnMet: 3.348 ± 1.434
2.232AsnAsn: 2.232 ± 0.553
5.58AsnPro: 5.58 ± 1.94
2.232AsnGln: 2.232 ± 1.852
0.0AsnArg: 0.0 ± 0.0
3.348AsnSer: 3.348 ± 2.066
0.0AsnThr: 0.0 ± 0.0
1.116AsnVal: 1.116 ± 0.979
1.116AsnTrp: 1.116 ± 0.689
1.116AsnTyr: 1.116 ± 0.689
0.0AsnXaa: 0.0 ± 0.0
Pro
4.464ProAla: 4.464 ± 1.344
0.0ProCys: 0.0 ± 0.0
2.232ProAsp: 2.232 ± 2.146
2.232ProGlu: 2.232 ± 1.959
1.116ProPhe: 1.116 ± 0.979
4.464ProGly: 4.464 ± 4.292
3.348ProHis: 3.348 ± 2.637
2.232ProIle: 2.232 ± 1.852
0.0ProLys: 0.0 ± 0.0
1.116ProLeu: 1.116 ± 0.689
0.0ProMet: 0.0 ± 0.0
3.348ProAsn: 3.348 ± 0.776
2.232ProPro: 2.232 ± 1.959
4.464ProGln: 4.464 ± 1.344
6.696ProArg: 6.696 ± 3.485
5.58ProSer: 5.58 ± 1.159
2.232ProThr: 2.232 ± 1.852
2.232ProVal: 2.232 ± 1.378
0.0ProTrp: 0.0 ± 0.0
1.116ProTyr: 1.116 ± 0.689
0.0ProXaa: 0.0 ± 0.0
Gln
2.232GlnAla: 2.232 ± 0.553
1.116GlnCys: 1.116 ± 0.979
3.348GlnAsp: 3.348 ± 0.776
0.0GlnGlu: 0.0 ± 0.0
3.348GlnPhe: 3.348 ± 2.066
1.116GlnGly: 1.116 ± 0.979
3.348GlnHis: 3.348 ± 1.653
0.0GlnIle: 0.0 ± 0.0
2.232GlnLys: 2.232 ± 1.378
1.116GlnLeu: 1.116 ± 0.689
1.116GlnMet: 1.116 ± 0.689
2.232GlnAsn: 2.232 ± 1.959
2.232GlnPro: 2.232 ± 0.553
0.0GlnGln: 0.0 ± 0.0
2.232GlnArg: 2.232 ± 1.378
2.232GlnSer: 2.232 ± 1.959
2.232GlnThr: 2.232 ± 1.378
3.348GlnVal: 3.348 ± 1.905
0.0GlnTrp: 0.0 ± 0.0
2.232GlnTyr: 2.232 ± 0.553
0.0GlnXaa: 0.0 ± 0.0
Arg
7.812ArgAla: 7.812 ± 4.821
1.116ArgCys: 1.116 ± 0.979
5.58ArgAsp: 5.58 ± 6.184
2.232ArgGlu: 2.232 ± 1.959
3.348ArgPhe: 3.348 ± 2.938
5.58ArgGly: 5.58 ± 2.01
4.464ArgHis: 4.464 ± 1.359
2.232ArgIle: 2.232 ± 0.553
4.464ArgLys: 4.464 ± 1.107
12.277ArgLeu: 12.277 ± 6.125
1.116ArgMet: 1.116 ± 2.043
2.232ArgAsn: 2.232 ± 1.378
3.348ArgPro: 3.348 ± 1.653
0.0ArgGln: 0.0 ± 0.0
7.812ArgArg: 7.812 ± 0.799
5.58ArgSer: 5.58 ± 6.184
3.348ArgThr: 3.348 ± 1.905
1.116ArgVal: 1.116 ± 0.689
2.232ArgTrp: 2.232 ± 1.378
4.464ArgTyr: 4.464 ± 1.107
0.0ArgXaa: 0.0 ± 0.0
Ser
5.58SerAla: 5.58 ± 1.159
2.232SerCys: 2.232 ± 1.852
1.116SerAsp: 1.116 ± 0.979
1.116SerGlu: 1.116 ± 0.689
2.232SerPhe: 2.232 ± 1.959
1.116SerGly: 1.116 ± 0.979
0.0SerHis: 0.0 ± 0.0
6.696SerIle: 6.696 ± 1.673
3.348SerLys: 3.348 ± 0.776
5.58SerLeu: 5.58 ± 1.159
3.348SerMet: 3.348 ± 0.776
2.232SerAsn: 2.232 ± 1.378
3.348SerPro: 3.348 ± 1.905
1.116SerGln: 1.116 ± 0.689
6.696SerArg: 6.696 ± 1.977
2.232SerSer: 2.232 ± 1.378
4.464SerThr: 4.464 ± 2.755
6.696SerVal: 6.696 ± 1.673
2.232SerTrp: 2.232 ± 0.553
3.348SerTyr: 3.348 ± 1.905
0.0SerXaa: 0.0 ± 0.0
Thr
5.58ThrAla: 5.58 ± 3.444
1.116ThrCys: 1.116 ± 0.689
5.58ThrAsp: 5.58 ± 1.159
2.232ThrGlu: 2.232 ± 0.553
7.812ThrPhe: 7.812 ± 1.295
4.464ThrGly: 4.464 ± 1.359
0.0ThrHis: 0.0 ± 0.0
1.116ThrIle: 1.116 ± 0.979
2.232ThrLys: 2.232 ± 1.378
13.393ThrLeu: 13.393 ± 6.78
1.116ThrMet: 1.116 ± 0.689
2.232ThrAsn: 2.232 ± 2.146
2.232ThrPro: 2.232 ± 1.852
4.464ThrGln: 4.464 ± 1.359
4.464ThrArg: 4.464 ± 3.703
4.464ThrSer: 4.464 ± 1.359
3.348ThrThr: 3.348 ± 0.776
1.116ThrVal: 1.116 ± 0.689
0.0ThrTrp: 0.0 ± 0.0
2.232ThrTyr: 2.232 ± 1.959
0.0ThrXaa: 0.0 ± 0.0
Val
2.232ValAla: 2.232 ± 1.378
1.116ValCys: 1.116 ± 0.979
3.348ValAsp: 3.348 ± 0.776
1.116ValGlu: 1.116 ± 0.979
2.232ValPhe: 2.232 ± 0.553
1.116ValGly: 1.116 ± 0.689
2.232ValHis: 2.232 ± 1.378
4.464ValIle: 4.464 ± 1.344
4.464ValLys: 4.464 ± 1.107
2.232ValLeu: 2.232 ± 2.146
1.116ValMet: 1.116 ± 0.689
4.464ValAsn: 4.464 ± 1.359
1.116ValPro: 1.116 ± 2.043
1.116ValGln: 1.116 ± 0.689
5.58ValArg: 5.58 ± 2.663
2.232ValSer: 2.232 ± 0.553
3.348ValThr: 3.348 ± 1.905
6.696ValVal: 6.696 ± 1.66
1.116ValTrp: 1.116 ± 0.689
2.232ValTyr: 2.232 ± 1.959
0.0ValXaa: 0.0 ± 0.0
Trp
1.116TrpAla: 1.116 ± 0.979
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
3.348TrpGlu: 3.348 ± 1.434
1.116TrpPhe: 1.116 ± 2.043
2.232TrpGly: 2.232 ± 0.553
1.116TrpHis: 1.116 ± 0.689
0.0TrpIle: 0.0 ± 0.0
1.116TrpLys: 1.116 ± 0.979
2.232TrpLeu: 2.232 ± 0.553
0.0TrpMet: 0.0 ± 0.0
2.232TrpAsn: 2.232 ± 0.553
0.0TrpPro: 0.0 ± 0.0
1.116TrpGln: 1.116 ± 0.689
1.116TrpArg: 1.116 ± 0.689
2.232TrpSer: 2.232 ± 0.553
1.116TrpThr: 1.116 ± 0.689
0.0TrpVal: 0.0 ± 0.0
1.116TrpTrp: 1.116 ± 0.979
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.348TyrAla: 3.348 ± 1.434
0.0TyrCys: 0.0 ± 0.0
3.348TyrAsp: 3.348 ± 0.776
0.0TyrGlu: 0.0 ± 0.0
3.348TyrPhe: 3.348 ± 0.776
1.116TyrGly: 1.116 ± 0.979
2.232TyrHis: 2.232 ± 1.378
3.348TyrIle: 3.348 ± 1.434
1.116TyrLys: 1.116 ± 0.689
2.232TyrLeu: 2.232 ± 1.852
1.116TyrMet: 1.116 ± 0.798
2.232TyrAsn: 2.232 ± 0.553
4.464TyrPro: 4.464 ± 1.344
1.116TyrGln: 1.116 ± 0.689
6.696TyrArg: 6.696 ± 2.68
0.0TyrSer: 0.0 ± 0.0
3.348TyrThr: 3.348 ± 1.434
3.348TyrVal: 3.348 ± 1.653
0.0TyrTrp: 0.0 ± 0.0
2.232TyrTyr: 2.232 ± 1.378
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (897 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski