Amino acid dipepetide frequency for Torque teno virus 20

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.828AlaAla: 18.828 ± 11.453
1.395AlaCys: 1.395 ± 0.713
6.276AlaAsp: 6.276 ± 2.678
2.789AlaGlu: 2.789 ± 1.08
6.276AlaPhe: 6.276 ± 2.678
2.789AlaGly: 2.789 ± 1.08
2.092AlaHis: 2.092 ± 1.474
2.789AlaIle: 2.789 ± 1.08
2.092AlaLys: 2.092 ± 0.787
3.487AlaLeu: 3.487 ± 0.722
0.697AlaMet: 0.697 ± 0.426
1.395AlaAsn: 1.395 ± 0.852
9.763AlaPro: 9.763 ± 5.127
2.092AlaGln: 2.092 ± 0.787
6.974AlaArg: 6.974 ± 3.129
0.697AlaSer: 0.697 ± 0.426
2.092AlaThr: 2.092 ± 0.665
0.697AlaVal: 0.697 ± 0.872
0.0AlaTrp: 0.0 ± 0.0
2.092AlaTyr: 2.092 ± 1.278
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.395CysAsp: 1.395 ± 0.852
0.0CysGlu: 0.0 ± 0.0
0.697CysPhe: 0.697 ± 0.426
2.789CysGly: 2.789 ± 1.08
0.0CysHis: 0.0 ± 0.0
0.697CysIle: 0.697 ± 0.426
0.697CysLys: 0.697 ± 0.872
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.697CysPro: 0.697 ± 0.426
0.0CysGln: 0.0 ± 0.0
1.395CysArg: 1.395 ± 0.852
1.395CysSer: 1.395 ± 1.528
4.184CysThr: 4.184 ± 0.489
1.395CysVal: 1.395 ± 0.852
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.789AspAla: 2.789 ± 2.06
0.697AspCys: 0.697 ± 0.764
5.579AspAsp: 5.579 ± 2.159
2.789AspGlu: 2.789 ± 1.08
2.092AspPhe: 2.092 ± 1.278
6.276AspGly: 6.276 ± 1.786
0.0AspHis: 0.0 ± 0.0
4.184AspIle: 4.184 ± 0.489
5.579AspLys: 5.579 ± 2.622
4.881AspLeu: 4.881 ± 0.815
0.0AspMet: 0.0 ± 0.0
1.395AspAsn: 1.395 ± 0.852
4.184AspPro: 4.184 ± 0.489
1.395AspGln: 1.395 ± 0.852
0.697AspArg: 0.697 ± 0.872
2.092AspSer: 2.092 ± 1.278
7.671AspThr: 7.671 ± 0.8
2.092AspVal: 2.092 ± 0.751
3.487AspTrp: 3.487 ± 1.673
2.092AspTyr: 2.092 ± 1.278
0.0AspXaa: 0.0 ± 0.0
Glu
3.487GluAla: 3.487 ± 1.673
0.697GluCys: 0.697 ± 0.764
2.789GluAsp: 2.789 ± 1.08
3.487GluGlu: 3.487 ± 2.131
0.697GluPhe: 0.697 ± 0.426
2.789GluGly: 2.789 ± 1.08
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
1.395GluLys: 1.395 ± 0.852
2.092GluLeu: 2.092 ± 1.278
2.092GluMet: 2.092 ± 0.665
2.789GluAsn: 2.789 ± 1.08
0.697GluPro: 0.697 ± 0.426
0.0GluGln: 0.0 ± 0.0
6.276GluArg: 6.276 ± 4.206
4.184GluSer: 4.184 ± 2.661
2.789GluThr: 2.789 ± 1.046
0.0GluVal: 0.0 ± 0.0
0.697GluTrp: 0.697 ± 0.426
3.487GluTyr: 3.487 ± 0.722
0.0GluXaa: 0.0 ± 0.0
Phe
2.092PheAla: 2.092 ± 1.474
3.487PheCys: 3.487 ± 0.722
2.092PheAsp: 2.092 ± 0.787
0.697PheGlu: 0.697 ± 0.426
0.0PhePhe: 0.0 ± 0.0
2.092PheGly: 2.092 ± 1.278
2.789PheHis: 2.789 ± 1.705
2.092PheIle: 2.092 ± 1.278
1.395PheLys: 1.395 ± 0.713
0.697PheLeu: 0.697 ± 0.426
0.0PheMet: 0.0 ± 0.0
2.789PheAsn: 2.789 ± 1.08
1.395PhePro: 1.395 ± 0.713
2.092PheGln: 2.092 ± 1.278
4.881PheArg: 4.881 ± 2.108
2.789PheSer: 2.789 ± 1.705
3.487PheThr: 3.487 ± 0.722
2.092PheVal: 2.092 ± 0.751
0.0PheTrp: 0.0 ± 0.0
4.881PheTyr: 4.881 ± 2.167
0.0PheXaa: 0.0 ± 0.0
Gly
8.368GlyAla: 8.368 ± 5.898
2.789GlyCys: 2.789 ± 1.08
6.276GlyAsp: 6.276 ± 3.361
0.697GlyGlu: 0.697 ± 0.426
1.395GlyPhe: 1.395 ± 0.713
11.158GlyGly: 11.158 ± 4.127
0.697GlyHis: 0.697 ± 0.426
0.0GlyIle: 0.0 ± 0.0
2.789GlyLys: 2.789 ± 1.243
2.092GlyLeu: 2.092 ± 1.331
2.789GlyMet: 2.789 ± 1.705
2.789GlyAsn: 2.789 ± 1.705
6.974GlyPro: 6.974 ± 2.295
0.697GlyGln: 0.697 ± 0.426
5.579GlyArg: 5.579 ± 0.809
2.789GlySer: 2.789 ± 1.049
2.789GlyThr: 2.789 ± 1.049
2.092GlyVal: 2.092 ± 0.751
0.697GlyTrp: 0.697 ± 0.426
1.395GlyTyr: 1.395 ± 0.852
0.0GlyXaa: 0.0 ± 0.0
His
2.092HisAla: 2.092 ± 1.474
0.0HisCys: 0.0 ± 0.0
0.697HisAsp: 0.697 ± 0.426
0.0HisGlu: 0.0 ± 0.0
2.789HisPhe: 2.789 ± 2.06
0.697HisGly: 0.697 ± 0.426
0.0HisHis: 0.0 ± 0.0
1.395HisIle: 1.395 ± 0.852
0.0HisLys: 0.0 ± 0.0
2.092HisLeu: 2.092 ± 1.278
0.0HisMet: 0.0 ± 0.0
1.395HisAsn: 1.395 ± 0.626
4.184HisPro: 4.184 ± 1.574
1.395HisGln: 1.395 ± 0.852
0.0HisArg: 0.0 ± 0.0
0.697HisSer: 0.697 ± 0.426
2.789HisThr: 2.789 ± 1.08
2.789HisVal: 2.789 ± 1.08
0.697HisTrp: 0.697 ± 0.426
0.697HisTyr: 0.697 ± 0.426
0.0HisXaa: 0.0 ± 0.0
Ile
1.395IleAla: 1.395 ± 0.852
1.395IleCys: 1.395 ± 0.852
3.487IleAsp: 3.487 ± 1.529
3.487IleGlu: 3.487 ± 0.722
0.697IlePhe: 0.697 ± 0.426
2.092IleGly: 2.092 ± 1.278
3.487IleHis: 3.487 ± 1.673
0.697IleIle: 0.697 ± 0.426
4.184IleLys: 4.184 ± 2.557
1.395IleLeu: 1.395 ± 0.626
0.0IleMet: 0.0 ± 0.0
0.697IleAsn: 0.697 ± 0.426
4.184IlePro: 4.184 ± 1.879
1.395IleGln: 1.395 ± 0.626
1.395IleArg: 1.395 ± 0.852
1.395IleSer: 1.395 ± 0.852
2.092IleThr: 2.092 ± 1.278
2.092IleVal: 2.092 ± 1.278
0.0IleTrp: 0.0 ± 0.0
0.697IleTyr: 0.697 ± 0.426
0.0IleXaa: 0.0 ± 0.0
Lys
6.974LysAla: 6.974 ± 1.685
1.395LysCys: 1.395 ± 0.852
1.395LysAsp: 1.395 ± 0.852
2.092LysGlu: 2.092 ± 1.331
2.092LysPhe: 2.092 ± 1.278
0.697LysGly: 0.697 ± 0.426
2.092LysHis: 2.092 ± 0.787
2.789LysIle: 2.789 ± 1.049
3.487LysLys: 3.487 ± 2.833
2.789LysLeu: 2.789 ± 1.243
0.697LysMet: 0.697 ± 0.426
2.092LysAsn: 2.092 ± 1.278
3.487LysPro: 3.487 ± 1.148
4.184LysGln: 4.184 ± 1.503
4.881LysArg: 4.881 ± 2.21
2.092LysSer: 2.092 ± 1.331
1.395LysThr: 1.395 ± 0.626
2.789LysVal: 2.789 ± 1.705
2.789LysTrp: 2.789 ± 1.705
1.395LysTyr: 1.395 ± 0.852
0.0LysXaa: 0.0 ± 0.0
Leu
4.881LeuAla: 4.881 ± 1.003
0.697LeuCys: 0.697 ± 0.426
3.487LeuAsp: 3.487 ± 1.316
2.092LeuGlu: 2.092 ± 0.751
5.579LeuPhe: 5.579 ± 0.809
4.184LeuGly: 4.184 ± 1.312
0.697LeuHis: 0.697 ± 0.872
2.092LeuIle: 2.092 ± 1.278
4.184LeuLys: 4.184 ± 2.557
1.395LeuLeu: 1.395 ± 0.852
0.697LeuMet: 0.697 ± 0.426
2.092LeuAsn: 2.092 ± 0.751
4.184LeuPro: 4.184 ± 1.922
6.276LeuGln: 6.276 ± 2.24
4.881LeuArg: 4.881 ± 2.983
4.184LeuSer: 4.184 ± 0.8
1.395LeuThr: 1.395 ± 0.852
3.487LeuVal: 3.487 ± 1.414
3.487LeuTrp: 3.487 ± 0.722
2.092LeuTyr: 2.092 ± 1.278
0.0LeuXaa: 0.0 ± 0.0
Met
1.395MetAla: 1.395 ± 0.852
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.395MetPhe: 1.395 ± 0.852
0.697MetGly: 0.697 ± 0.426
0.0MetHis: 0.0 ± 0.0
0.697MetIle: 0.697 ± 0.426
0.697MetLys: 0.697 ± 0.426
1.395MetLeu: 1.395 ± 0.852
0.0MetMet: 0.0 ± 0.0
0.697MetAsn: 0.697 ± 0.426
1.395MetPro: 1.395 ± 0.713
1.395MetGln: 1.395 ± 0.713
2.789MetArg: 2.789 ± 2.06
3.487MetSer: 3.487 ± 0.722
0.697MetThr: 0.697 ± 0.426
0.697MetVal: 0.697 ± 0.426
0.0MetTrp: 0.0 ± 0.0
0.697MetTyr: 0.697 ± 0.764
0.0MetXaa: 0.0 ± 0.0
Asn
1.395AsnAla: 1.395 ± 0.852
0.0AsnCys: 0.0 ± 0.0
1.395AsnAsp: 1.395 ± 0.852
0.697AsnGlu: 0.697 ± 0.426
2.789AsnPhe: 2.789 ± 1.705
0.697AsnGly: 0.697 ± 0.426
0.0AsnHis: 0.0 ± 0.0
0.697AsnIle: 0.697 ± 0.426
2.789AsnLys: 2.789 ± 1.705
4.184AsnLeu: 4.184 ± 1.312
0.697AsnMet: 0.697 ± 0.426
1.395AsnAsn: 1.395 ± 0.852
9.763AsnPro: 9.763 ± 1.131
0.0AsnGln: 0.0 ± 0.0
1.395AsnArg: 1.395 ± 1.033
1.395AsnSer: 1.395 ± 1.033
1.395AsnThr: 1.395 ± 0.852
0.0AsnVal: 0.0 ± 0.0
0.697AsnTrp: 0.697 ± 0.426
2.092AsnTyr: 2.092 ± 0.751
0.0AsnXaa: 0.0 ± 0.0
Pro
6.276ProAla: 6.276 ± 5.28
1.395ProCys: 1.395 ± 0.852
4.184ProAsp: 4.184 ± 0.489
2.789ProGlu: 2.789 ± 2.06
2.789ProPhe: 2.789 ± 1.046
4.184ProGly: 4.184 ± 1.312
0.697ProHis: 0.697 ± 0.426
3.487ProIle: 3.487 ± 1.316
3.487ProLys: 3.487 ± 1.39
6.974ProLeu: 6.974 ± 1.786
4.184ProMet: 4.184 ± 1.941
1.395ProAsn: 1.395 ± 0.852
9.763ProPro: 9.763 ± 4.333
6.974ProGln: 6.974 ± 3.934
7.671ProArg: 7.671 ± 0.8
9.066ProSer: 9.066 ± 3.42
6.276ProThr: 6.276 ± 1.584
5.579ProVal: 5.579 ± 2.159
2.092ProTrp: 2.092 ± 0.665
3.487ProTyr: 3.487 ± 0.532
0.0ProXaa: 0.0 ± 0.0
Gln
2.092GlnAla: 2.092 ± 1.535
0.0GlnCys: 0.0 ± 0.0
1.395GlnAsp: 1.395 ± 0.852
1.395GlnGlu: 1.395 ± 0.852
0.697GlnPhe: 0.697 ± 0.426
2.789GlnGly: 2.789 ± 1.928
2.789GlnHis: 2.789 ± 1.705
0.0GlnIle: 0.0 ± 0.0
2.092GlnLys: 2.092 ± 1.331
2.789GlnLeu: 2.789 ± 1.705
0.697GlnMet: 0.697 ± 0.842
1.395GlnAsn: 1.395 ± 0.713
1.395GlnPro: 1.395 ± 0.626
4.184GlnGln: 4.184 ± 1.148
2.789GlnArg: 2.789 ± 1.253
4.881GlnSer: 4.881 ± 1.792
4.881GlnThr: 4.881 ± 0.815
2.789GlnVal: 2.789 ± 1.705
3.487GlnTrp: 3.487 ± 0.722
0.697GlnTyr: 0.697 ± 0.426
0.0GlnXaa: 0.0 ± 0.0
Arg
5.579ArgAla: 5.579 ± 3.072
0.0ArgCys: 0.0 ± 0.0
9.763ArgAsp: 9.763 ± 1.312
4.184ArgGlu: 4.184 ± 1.922
2.789ArgPhe: 2.789 ± 1.08
9.066ArgGly: 9.066 ± 1.974
5.579ArgHis: 5.579 ± 2.937
2.092ArgIle: 2.092 ± 1.278
7.671ArgLys: 7.671 ± 1.124
3.487ArgLeu: 3.487 ± 0.532
1.395ArgMet: 1.395 ± 0.787
0.697ArgAsn: 0.697 ± 0.764
6.974ArgPro: 6.974 ± 1.444
0.0ArgGln: 0.0 ± 0.0
25.105ArgArg: 25.105 ± 6.486
5.579ArgSer: 5.579 ± 1.983
1.395ArgThr: 1.395 ± 0.626
3.487ArgVal: 3.487 ± 1.44
2.092ArgTrp: 2.092 ± 1.278
4.184ArgTyr: 4.184 ± 2.557
0.0ArgXaa: 0.0 ± 0.0
Ser
2.092SerAla: 2.092 ± 0.751
0.697SerCys: 0.697 ± 0.426
1.395SerAsp: 1.395 ± 0.852
4.881SerGlu: 4.881 ± 2.86
3.487SerPhe: 3.487 ± 1.39
2.789SerGly: 2.789 ± 1.253
0.0SerHis: 0.0 ± 0.0
3.487SerIle: 3.487 ± 1.935
2.789SerLys: 2.789 ± 3.056
3.487SerLeu: 3.487 ± 1.529
0.0SerMet: 0.0 ± 0.0
2.789SerAsn: 2.789 ± 1.426
8.368SerPro: 8.368 ± 4.28
0.697SerGln: 0.697 ± 0.426
4.881SerArg: 4.881 ± 2.399
9.066SerSer: 9.066 ± 7.946
8.368SerThr: 8.368 ± 3.006
4.881SerVal: 4.881 ± 0.566
0.0SerTrp: 0.0 ± 0.0
6.276SerTyr: 6.276 ± 1.417
0.0SerXaa: 0.0 ± 0.0
Thr
1.395ThrAla: 1.395 ± 0.852
0.0ThrCys: 0.0 ± 0.0
3.487ThrAsp: 3.487 ± 1.414
2.092ThrGlu: 2.092 ± 0.787
2.789ThrPhe: 2.789 ± 1.705
5.579ThrGly: 5.579 ± 0.611
1.395ThrHis: 1.395 ± 0.852
3.487ThrIle: 3.487 ± 1.39
2.789ThrLys: 2.789 ± 1.253
4.184ThrLeu: 4.184 ± 1.806
1.395ThrMet: 1.395 ± 0.852
2.789ThrAsn: 2.789 ± 1.08
4.184ThrPro: 4.184 ± 2.162
4.881ThrGln: 4.881 ± 1.003
3.487ThrArg: 3.487 ± 2.347
10.46ThrSer: 10.46 ± 1.848
3.487ThrThr: 3.487 ± 1.44
2.092ThrVal: 2.092 ± 1.278
0.0ThrTrp: 0.0 ± 0.0
1.395ThrTyr: 1.395 ± 0.852
0.0ThrXaa: 0.0 ± 0.0
Val
1.395ValAla: 1.395 ± 0.852
0.697ValCys: 0.697 ± 0.426
0.697ValAsp: 0.697 ± 0.426
3.487ValGlu: 3.487 ± 0.722
1.395ValPhe: 1.395 ± 0.626
2.092ValGly: 2.092 ± 0.751
1.395ValHis: 1.395 ± 0.852
3.487ValIle: 3.487 ± 0.722
1.395ValLys: 1.395 ± 0.852
9.066ValLeu: 9.066 ± 0.968
0.697ValMet: 0.697 ± 0.426
1.395ValAsn: 1.395 ± 0.713
6.276ValPro: 6.276 ± 0.667
3.487ValGln: 3.487 ± 2.131
1.395ValArg: 1.395 ± 0.852
2.092ValSer: 2.092 ± 0.787
2.092ValThr: 2.092 ± 0.751
1.395ValVal: 1.395 ± 0.852
0.0ValTrp: 0.0 ± 0.0
0.697ValTyr: 0.697 ± 0.872
0.0ValXaa: 0.0 ± 0.0
Trp
0.697TrpAla: 0.697 ± 0.426
0.0TrpCys: 0.0 ± 0.0
0.697TrpAsp: 0.697 ± 0.426
2.092TrpGlu: 2.092 ± 0.787
0.0TrpPhe: 0.0 ± 0.0
1.395TrpGly: 1.395 ± 0.626
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.092TrpLeu: 2.092 ± 1.278
0.697TrpMet: 0.697 ± 0.872
0.0TrpAsn: 0.0 ± 0.0
3.487TrpPro: 3.487 ± 0.722
0.697TrpGln: 0.697 ± 0.426
5.579TrpArg: 5.579 ± 0.875
0.697TrpSer: 0.697 ± 0.426
0.0TrpThr: 0.0 ± 0.0
2.789TrpVal: 2.789 ± 1.08
0.697TrpTrp: 0.697 ± 0.426
0.697TrpTyr: 0.697 ± 0.426
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.092TyrAla: 2.092 ± 1.278
0.0TyrCys: 0.0 ± 0.0
3.487TyrAsp: 3.487 ± 2.131
0.697TyrGlu: 0.697 ± 0.764
1.395TyrPhe: 1.395 ± 0.852
0.0TyrGly: 0.0 ± 0.0
0.697TyrHis: 0.697 ± 0.426
2.092TyrIle: 2.092 ± 1.278
2.092TyrLys: 2.092 ± 0.751
3.487TyrLeu: 3.487 ± 1.44
0.697TyrMet: 0.697 ± 0.633
3.487TyrAsn: 3.487 ± 2.131
2.092TyrPro: 2.092 ± 0.787
1.395TyrGln: 1.395 ± 0.852
9.066TyrArg: 9.066 ± 2.084
1.395TyrSer: 1.395 ± 1.528
2.092TyrThr: 2.092 ± 1.278
1.395TyrVal: 1.395 ± 0.852
1.395TyrTrp: 1.395 ± 0.852
1.395TyrTyr: 1.395 ± 0.626
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1435 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski