Amino acid dipepetide frequency for Morganella morganii subsp. morganii KT

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.583AlaAla: 10.583 ± 0.143	1.029AlaCys: 1.029 ± 0.031	5.869AlaAsp: 5.869 ± 0.082	6.325AlaGlu: 6.325 ± 0.099	3.552AlaPhe: 3.552 ± 0.056	8.28AlaGly: 8.28 ± 0.102	1.594AlaHis: 1.594 ± 0.039	5.418AlaIle: 5.418 ± 0.083	4.064AlaLys: 4.064 ± 0.069	10.723AlaLeu: 10.723 ± 0.125	2.748AlaMet: 2.748 ± 0.052	2.712AlaAsn: 2.712 ± 0.047	3.423AlaPro: 3.423 ± 0.06	4.305AlaGln: 4.305 ± 0.078	4.731AlaArg: 4.731 ± 0.077	4.218AlaSer: 4.218 ± 0.069	4.226AlaThr: 4.226 ± 0.064	7.341AlaVal: 7.341 ± 0.09	1.087AlaTrp: 1.087 ± 0.036	2.338AlaTyr: 2.338 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.976CysAla: 0.976 ± 0.031	0.195CysCys: 0.195 ± 0.015	0.684CysAsp: 0.684 ± 0.028	0.624CysGlu: 0.624 ± 0.027	0.448CysPhe: 0.448 ± 0.025	1.133CysGly: 1.133 ± 0.033	0.336CysHis: 0.336 ± 0.02	0.612CysIle: 0.612 ± 0.026	0.368CysLys: 0.368 ± 0.017	1.036CysLeu: 1.036 ± 0.031	0.242CysMet: 0.242 ± 0.014	0.34CysAsn: 0.34 ± 0.018	0.537CysPro: 0.537 ± 0.023	0.462CysGln: 0.462 ± 0.02	0.708CysArg: 0.708 ± 0.029	0.683CysSer: 0.683 ± 0.028	0.559CysThr: 0.559 ± 0.023	0.697CysVal: 0.697 ± 0.027	0.142CysTrp: 0.142 ± 0.012	0.384CysTyr: 0.384 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.938AspAla: 4.938 ± 0.073	0.556AspCys: 0.556 ± 0.025	3.184AspAsp: 3.184 ± 0.062	3.728AspGlu: 3.728 ± 0.075	2.275AspPhe: 2.275 ± 0.043	4.0AspGly: 4.0 ± 0.074	1.029AspHis: 1.029 ± 0.034	4.161AspIle: 4.161 ± 0.056	2.979AspLys: 2.979 ± 0.058	4.753AspLeu: 4.753 ± 0.07	1.444AspMet: 1.444 ± 0.037	2.678AspAsn: 2.678 ± 0.053	2.388AspPro: 2.388 ± 0.046	1.433AspGln: 1.433 ± 0.034	2.403AspArg: 2.403 ± 0.054	3.075AspSer: 3.075 ± 0.054	2.877AspThr: 2.877 ± 0.055	3.734AspVal: 3.734 ± 0.066	0.808AspTrp: 0.808 ± 0.027	2.057AspTyr: 2.057 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	4.768GluAla: 4.768 ± 0.074	0.573GluCys: 0.573 ± 0.025	2.503GluAsp: 2.503 ± 0.051	3.501GluGlu: 3.501 ± 0.073	2.021GluPhe: 2.021 ± 0.047	3.289GluGly: 3.289 ± 0.048	1.402GluHis: 1.402 ± 0.037	3.698GluIle: 3.698 ± 0.062	3.873GluLys: 3.873 ± 0.073	5.926GluLeu: 5.926 ± 0.086	1.804GluMet: 1.804 ± 0.042	2.829GluAsn: 2.829 ± 0.054	2.145GluPro: 2.145 ± 0.055	3.333GluGln: 3.333 ± 0.072	3.238GluArg: 3.238 ± 0.067	3.143GluSer: 3.143 ± 0.059	3.301GluThr: 3.301 ± 0.061	3.385GluVal: 3.385 ± 0.062	0.715GluTrp: 0.715 ± 0.028	1.615GluTyr: 1.615 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	3.62PheAla: 3.62 ± 0.058	0.556PheCys: 0.556 ± 0.024	2.343PheAsp: 2.343 ± 0.048	1.775PheGlu: 1.775 ± 0.044	1.822PhePhe: 1.822 ± 0.053	3.099PheGly: 3.099 ± 0.066	0.731PheHis: 0.731 ± 0.028	2.851PheIle: 2.851 ± 0.053	1.38PheLys: 1.38 ± 0.038	3.506PheLeu: 3.506 ± 0.062	1.104PheMet: 1.104 ± 0.031	1.719PheAsn: 1.719 ± 0.04	1.594PhePro: 1.594 ± 0.039	0.995PheGln: 0.995 ± 0.031	2.132PheArg: 2.132 ± 0.042	3.413PheSer: 3.413 ± 0.06	2.641PheThr: 2.641 ± 0.056	2.445PheVal: 2.445 ± 0.053	0.537PheTrp: 0.537 ± 0.025	1.357PheTyr: 1.357 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.99GlyAla: 5.99 ± 0.082	1.042GlyCys: 1.042 ± 0.033	3.755GlyAsp: 3.755 ± 0.063	4.396GlyGlu: 4.396 ± 0.064	3.326GlyPhe: 3.326 ± 0.058	5.458GlyGly: 5.458 ± 0.091	1.646GlyHis: 1.646 ± 0.041	5.37GlyIle: 5.37 ± 0.079	4.175GlyLys: 4.175 ± 0.061	7.434GlyLeu: 7.434 ± 0.091	2.401GlyMet: 2.401 ± 0.053	2.895GlyAsn: 2.895 ± 0.074	1.772GlyPro: 1.772 ± 0.039	2.796GlyGln: 2.796 ± 0.056	3.697GlyArg: 3.697 ± 0.06	4.11GlySer: 4.11 ± 0.077	4.009GlyThr: 4.009 ± 0.077	5.39GlyVal: 5.39 ± 0.077	1.12GlyTrp: 1.12 ± 0.033	2.66GlyTyr: 2.66 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	1.632HisAla: 1.632 ± 0.042	0.329HisCys: 0.329 ± 0.019	1.12HisAsp: 1.12 ± 0.038	1.079HisGlu: 1.079 ± 0.032	1.035HisPhe: 1.035 ± 0.029	1.529HisGly: 1.529 ± 0.038	0.717HisHis: 0.717 ± 0.03	1.366HisIle: 1.366 ± 0.04	0.791HisLys: 0.791 ± 0.025	2.078HisLeu: 2.078 ± 0.049	0.557HisMet: 0.557 ± 0.023	0.85HisAsn: 0.85 ± 0.032	1.266HisPro: 1.266 ± 0.037	1.022HisGln: 1.022 ± 0.031	1.143HisArg: 1.143 ± 0.03	1.237HisSer: 1.237 ± 0.032	1.135HisThr: 1.135 ± 0.032	1.128HisVal: 1.128 ± 0.033	0.338HisTrp: 0.338 ± 0.019	0.941HisTyr: 0.941 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.597IleAla: 6.597 ± 0.082	0.735IleCys: 0.735 ± 0.027	3.595IleAsp: 3.595 ± 0.053	3.277IleGlu: 3.277 ± 0.068	2.325IlePhe: 2.325 ± 0.053	4.644IleGly: 4.644 ± 0.076	1.148IleHis: 1.148 ± 0.03	4.153IleIle: 4.153 ± 0.087	2.577IleLys: 2.577 ± 0.044	5.663IleLeu: 5.663 ± 0.077	1.397IleMet: 1.397 ± 0.04	2.838IleAsn: 2.838 ± 0.052	3.072IlePro: 3.072 ± 0.059	1.883IleGln: 1.883 ± 0.041	3.696IleArg: 3.696 ± 0.054	4.481IleSer: 4.481 ± 0.075	4.334IleThr: 4.334 ± 0.067	3.814IleVal: 3.814 ± 0.069	0.642IleTrp: 0.642 ± 0.025	1.742IleTyr: 1.742 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	4.289LysAla: 4.289 ± 0.078	0.299LysCys: 0.299 ± 0.018	2.28LysAsp: 2.28 ± 0.052	2.705LysGlu: 2.705 ± 0.053	1.248LysPhe: 1.248 ± 0.034	3.067LysGly: 3.067 ± 0.057	0.862LysHis: 0.862 ± 0.031	2.764LysIle: 2.764 ± 0.051	2.746LysLys: 2.746 ± 0.066	4.462LysLeu: 4.462 ± 0.065	1.437LysMet: 1.437 ± 0.036	2.171LysAsn: 2.171 ± 0.055	2.264LysPro: 2.264 ± 0.059	2.284LysGln: 2.284 ± 0.053	2.483LysArg: 2.483 ± 0.048	2.667LysSer: 2.667 ± 0.057	3.052LysThr: 3.052 ± 0.06	2.925LysVal: 2.925 ± 0.065	0.487LysTrp: 0.487 ± 0.023	1.294LysTyr: 1.294 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	10.319LeuAla: 10.319 ± 0.115	1.246LeuCys: 1.246 ± 0.038	5.157LeuAsp: 5.157 ± 0.082	4.707LeuGlu: 4.707 ± 0.075	4.423LeuPhe: 4.423 ± 0.068	6.801LeuGly: 6.801 ± 0.089	2.113LeuHis: 2.113 ± 0.051	6.494LeuIle: 6.494 ± 0.098	4.694LeuLys: 4.694 ± 0.07	11.36LeuLeu: 11.36 ± 0.162	2.837LeuMet: 2.837 ± 0.06	4.328LeuAsn: 4.328 ± 0.065	5.597LeuPro: 5.597 ± 0.083	3.586LeuGln: 3.586 ± 0.065	5.625LeuArg: 5.625 ± 0.089	7.815LeuSer: 7.815 ± 0.102	7.142LeuThr: 7.142 ± 0.086	6.315LeuVal: 6.315 ± 0.09	1.228LeuTrp: 1.228 ± 0.036	2.73LeuTyr: 2.73 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.823MetAla: 2.823 ± 0.047	0.218MetCys: 0.218 ± 0.014	1.269MetAsp: 1.269 ± 0.033	1.208MetGlu: 1.208 ± 0.036	0.868MetPhe: 0.868 ± 0.029	1.741MetGly: 1.741 ± 0.049	0.496MetHis: 0.496 ± 0.019	1.672MetIle: 1.672 ± 0.037	1.519MetLys: 1.519 ± 0.038	2.956MetLeu: 2.956 ± 0.057	0.929MetMet: 0.929 ± 0.034	1.169MetAsn: 1.169 ± 0.03	1.369MetPro: 1.369 ± 0.033	1.223MetGln: 1.223 ± 0.03	1.348MetArg: 1.348 ± 0.04	1.959MetSer: 1.959 ± 0.042	1.974MetThr: 1.974 ± 0.047	1.805MetVal: 1.805 ± 0.039	0.245MetTrp: 0.245 ± 0.015	0.606MetTyr: 0.606 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.4AsnAla: 3.4 ± 0.063	0.393AsnCys: 0.393 ± 0.021	2.147AsnAsp: 2.147 ± 0.048	2.041AsnGlu: 2.041 ± 0.048	1.256AsnPhe: 1.256 ± 0.033	3.107AsnGly: 3.107 ± 0.071	0.866AsnHis: 0.866 ± 0.031	2.832AsnIle: 2.832 ± 0.062	1.959AsnLys: 1.959 ± 0.056	3.508AsnLeu: 3.508 ± 0.057	1.013AsnMet: 1.013 ± 0.028	1.972AsnAsn: 1.972 ± 0.061	2.207AsnPro: 2.207 ± 0.053	1.53AsnGln: 1.53 ± 0.046	2.117AsnArg: 2.117 ± 0.042	2.233AsnSer: 2.233 ± 0.05	2.327AsnThr: 2.327 ± 0.047	2.345AsnVal: 2.345 ± 0.05	0.49AsnTrp: 0.49 ± 0.023	1.275AsnTyr: 1.275 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	4.835ProAla: 4.835 ± 0.072	0.393ProCys: 0.393 ± 0.019	3.339ProAsp: 3.339 ± 0.056	3.829ProGlu: 3.829 ± 0.062	1.854ProPhe: 1.854 ± 0.037	3.367ProGly: 3.367 ± 0.062	0.944ProHis: 0.944 ± 0.03	1.593ProIle: 1.593 ± 0.041	1.505ProLys: 1.505 ± 0.047	4.717ProLeu: 4.717 ± 0.07	1.043ProMet: 1.043 ± 0.031	1.129ProAsn: 1.129 ± 0.035	1.738ProPro: 1.738 ± 0.052	2.108ProGln: 2.108 ± 0.053	1.814ProArg: 1.814 ± 0.038	2.257ProSer: 2.257 ± 0.046	1.538ProThr: 1.538 ± 0.041	4.594ProVal: 4.594 ± 0.068	0.574ProTrp: 0.574 ± 0.027	1.343ProTyr: 1.343 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.202GlnAla: 4.202 ± 0.079	0.417GlnCys: 0.417 ± 0.021	1.873GlnAsp: 1.873 ± 0.047	2.15GlnGlu: 2.15 ± 0.048	1.582GlnPhe: 1.582 ± 0.041	2.759GlnGly: 2.759 ± 0.051	1.021GlnHis: 1.021 ± 0.034	2.462GlnIle: 2.462 ± 0.047	1.995GlnLys: 1.995 ± 0.047	4.492GlnLeu: 4.492 ± 0.064	1.204GlnMet: 1.204 ± 0.036	1.499GlnAsn: 1.499 ± 0.038	1.907GlnPro: 1.907 ± 0.046	2.714GlnGln: 2.714 ± 0.084	2.582GlnArg: 2.582 ± 0.058	2.363GlnSer: 2.363 ± 0.051	2.254GlnThr: 2.254 ± 0.053	2.721GlnVal: 2.721 ± 0.056	0.657GlnTrp: 0.657 ± 0.029	1.267GlnTyr: 1.267 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	4.311ArgAla: 4.311 ± 0.067	0.565ArgCys: 0.565 ± 0.024	3.075ArgAsp: 3.075 ± 0.056	3.694ArgGlu: 3.694 ± 0.063	2.538ArgPhe: 2.538 ± 0.055	3.223ArgGly: 3.223 ± 0.058	1.513ArgHis: 1.513 ± 0.04	3.527ArgIle: 3.527 ± 0.063	2.481ArgLys: 2.481 ± 0.045	5.873ArgLeu: 5.873 ± 0.083	1.424ArgMet: 1.424 ± 0.039	2.132ArgAsn: 2.132 ± 0.047	2.169ArgPro: 2.169 ± 0.04	2.762ArgGln: 2.762 ± 0.056	3.525ArgArg: 3.525 ± 0.07	2.615ArgSer: 2.615 ± 0.051	2.573ArgThr: 2.573 ± 0.046	3.364ArgVal: 3.364 ± 0.062	0.789ArgTrp: 0.789 ± 0.027	2.214ArgTyr: 2.214 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.093SerAla: 6.093 ± 0.086	0.603SerCys: 0.603 ± 0.026	3.464SerAsp: 3.464 ± 0.058	3.399SerGlu: 3.399 ± 0.059	2.302SerPhe: 2.302 ± 0.053	5.608SerGly: 5.608 ± 0.092	1.431SerHis: 1.431 ± 0.033	2.76SerIle: 2.76 ± 0.057	2.192SerLys: 2.192 ± 0.051	6.625SerLeu: 6.625 ± 0.08	1.438SerMet: 1.438 ± 0.035	1.802SerAsn: 1.802 ± 0.045	2.793SerPro: 2.793 ± 0.046	2.531SerGln: 2.531 ± 0.047	3.547SerArg: 3.547 ± 0.06	3.302SerSer: 3.302 ± 0.062	2.653SerThr: 2.653 ± 0.06	4.778SerVal: 4.778 ± 0.065	0.82SerTrp: 0.82 ± 0.031	1.744SerTyr: 1.744 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	5.532ThrAla: 5.532 ± 0.076	0.544ThrCys: 0.544 ± 0.024	3.39ThrAsp: 3.39 ± 0.064	3.519ThrGlu: 3.519 ± 0.055	2.13ThrPhe: 2.13 ± 0.05	5.33ThrGly: 5.33 ± 0.076	1.127ThrHis: 1.127 ± 0.029	3.238ThrIle: 3.238 ± 0.069	1.795ThrLys: 1.795 ± 0.042	6.87ThrLeu: 6.87 ± 0.099	1.13ThrMet: 1.13 ± 0.029	1.634ThrAsn: 1.634 ± 0.035	3.241ThrPro: 3.241 ± 0.054	2.263ThrGln: 2.263 ± 0.053	3.03ThrArg: 3.03 ± 0.052	2.699ThrSer: 2.699 ± 0.062	2.968ThrThr: 2.968 ± 0.062	4.03ThrVal: 4.03 ± 0.084	0.659ThrTrp: 0.659 ± 0.027	1.444ThrTyr: 1.444 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	6.319ValAla: 6.319 ± 0.093	0.862ValCys: 0.862 ± 0.026	3.136ValAsp: 3.136 ± 0.064	3.077ValGlu: 3.077 ± 0.053	2.647ValPhe: 2.647 ± 0.055	3.998ValGly: 3.998 ± 0.072	1.142ValHis: 1.142 ± 0.035	5.239ValIle: 5.239 ± 0.072	3.171ValLys: 3.171 ± 0.066	7.196ValLeu: 7.196 ± 0.084	2.243ValMet: 2.243 ± 0.043	2.779ValAsn: 2.779 ± 0.059	3.026ValPro: 3.026 ± 0.06	2.223ValGln: 2.223 ± 0.05	3.619ValArg: 3.619 ± 0.057	4.985ValSer: 4.985 ± 0.081	4.814ValThr: 4.814 ± 0.08	5.112ValVal: 5.112 ± 0.09	0.839ValTrp: 0.839 ± 0.028	1.906ValTyr: 1.906 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.864TrpAla: 0.864 ± 0.03	0.189TrpCys: 0.189 ± 0.013	0.583TrpAsp: 0.583 ± 0.024	0.554TrpGlu: 0.554 ± 0.026	0.644TrpPhe: 0.644 ± 0.026	0.768TrpGly: 0.768 ± 0.027	0.349TrpHis: 0.349 ± 0.018	0.677TrpIle: 0.677 ± 0.026	0.482TrpLys: 0.482 ± 0.022	2.012TrpLeu: 2.012 ± 0.056	0.377TrpMet: 0.377 ± 0.019	0.402TrpAsn: 0.402 ± 0.021	0.522TrpPro: 0.522 ± 0.023	0.985TrpGln: 0.985 ± 0.032	0.81TrpArg: 0.81 ± 0.028	0.715TrpSer: 0.715 ± 0.025	0.516TrpThr: 0.516 ± 0.024	0.787TrpVal: 0.787 ± 0.027	0.199TrpTrp: 0.199 ± 0.012	0.389TrpTyr: 0.389 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.476TyrAla: 2.476 ± 0.048	0.423TyrCys: 0.423 ± 0.018	1.739TyrAsp: 1.739 ± 0.041	1.476TyrGlu: 1.476 ± 0.04	1.325TyrPhe: 1.325 ± 0.035	2.241TyrGly: 2.241 ± 0.049	0.827TyrHis: 0.827 ± 0.03	1.723TyrIle: 1.723 ± 0.041	1.04TyrLys: 1.04 ± 0.037	3.324TyrLeu: 3.324 ± 0.057	0.626TyrMet: 0.626 ± 0.027	1.141TyrAsn: 1.141 ± 0.035	1.482TyrPro: 1.482 ± 0.036	1.682TyrGln: 1.682 ± 0.042	2.119TyrArg: 2.119 ± 0.042	1.913TyrSer: 1.913 ± 0.052	1.68TyrThr: 1.68 ± 0.047	1.623TyrVal: 1.623 ± 0.045	0.449TyrTrp: 0.449 ± 0.022	1.089TyrTyr: 1.089 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3510 proteins (1093174 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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