Amino acid dipepetide frequency for Tortoise microvirus 92

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.048AlaAla: 12.048 ± 4.892
0.0AlaCys: 0.0 ± 0.0
3.012AlaAsp: 3.012 ± 1.694
6.024AlaGlu: 6.024 ± 1.738
3.012AlaPhe: 3.012 ± 0.82
7.53AlaGly: 7.53 ± 2.603
1.506AlaHis: 1.506 ± 1.104
4.518AlaIle: 4.518 ± 0.988
6.777AlaLys: 6.777 ± 2.13
10.542AlaLeu: 10.542 ± 2.132
0.753AlaMet: 0.753 ± 0.635
4.518AlaAsn: 4.518 ± 1.477
3.765AlaPro: 3.765 ± 1.227
4.518AlaGln: 4.518 ± 1.197
8.283AlaArg: 8.283 ± 0.874
5.271AlaSer: 5.271 ± 1.453
5.271AlaThr: 5.271 ± 1.105
6.024AlaVal: 6.024 ± 2.615
0.0AlaTrp: 0.0 ± 0.0
1.506AlaTyr: 1.506 ± 0.559
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.753CysCys: 0.753 ± 0.633
0.753CysAsp: 0.753 ± 0.633
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.506CysGly: 1.506 ± 1.267
0.753CysHis: 0.753 ± 0.633
0.753CysIle: 0.753 ± 0.633
0.753CysLys: 0.753 ± 0.633
0.753CysLeu: 0.753 ± 0.633
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.753CysPro: 0.753 ± 0.633
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.506CysThr: 1.506 ± 1.267
0.753CysVal: 0.753 ± 0.635
0.0CysTrp: 0.0 ± 0.0
0.753CysTyr: 0.753 ± 0.566
0.0CysXaa: 0.0 ± 0.0
Asp
6.777AspAla: 6.777 ± 1.506
0.0AspCys: 0.0 ± 0.0
5.271AspAsp: 5.271 ± 2.404
1.506AspGlu: 1.506 ± 1.267
2.259AspPhe: 2.259 ± 0.802
3.012AspGly: 3.012 ± 0.877
0.0AspHis: 0.0 ± 0.0
3.765AspIle: 3.765 ± 1.227
3.765AspLys: 3.765 ± 0.839
4.518AspLeu: 4.518 ± 1.131
2.259AspMet: 2.259 ± 1.109
1.506AspAsn: 1.506 ± 0.559
3.012AspPro: 3.012 ± 1.926
0.753AspGln: 0.753 ± 0.566
3.765AspArg: 3.765 ± 2.072
3.765AspSer: 3.765 ± 1.032
2.259AspThr: 2.259 ± 1.697
4.518AspVal: 4.518 ± 0.734
0.753AspTrp: 0.753 ± 0.566
2.259AspTyr: 2.259 ± 1.697
0.0AspXaa: 0.0 ± 0.0
Glu
3.765GluAla: 3.765 ± 0.495
0.753GluCys: 0.753 ± 0.566
3.012GluAsp: 3.012 ± 0.869
5.271GluGlu: 5.271 ± 2.791
3.012GluPhe: 3.012 ± 0.82
1.506GluGly: 1.506 ± 0.643
2.259GluHis: 2.259 ± 0.928
1.506GluIle: 1.506 ± 1.083
2.259GluLys: 2.259 ± 0.374
3.765GluLeu: 3.765 ± 1.02
3.012GluMet: 3.012 ± 1.463
1.506GluAsn: 1.506 ± 1.267
3.012GluPro: 3.012 ± 1.694
0.753GluGln: 0.753 ± 0.921
4.518GluArg: 4.518 ± 1.677
3.765GluSer: 3.765 ± 1.973
5.271GluThr: 5.271 ± 2.583
3.012GluVal: 3.012 ± 2.263
0.0GluTrp: 0.0 ± 0.0
3.765GluTyr: 3.765 ± 1.625
0.0GluXaa: 0.0 ± 0.0
Phe
3.765PheAla: 3.765 ± 1.425
1.506PheCys: 1.506 ± 1.267
0.753PheAsp: 0.753 ± 0.635
1.506PheGlu: 1.506 ± 1.104
0.0PhePhe: 0.0 ± 0.0
3.765PheGly: 3.765 ± 1.366
0.0PheHis: 0.0 ± 0.0
1.506PheIle: 1.506 ± 1.131
1.506PheLys: 1.506 ± 0.643
0.0PheLeu: 0.0 ± 0.0
0.753PheMet: 0.753 ± 0.635
4.518PheAsn: 4.518 ± 1.702
0.753PhePro: 0.753 ± 0.566
0.0PheGln: 0.0 ± 0.0
5.271PheArg: 5.271 ± 0.822
1.506PheSer: 1.506 ± 0.643
0.753PheThr: 0.753 ± 0.566
4.518PheVal: 4.518 ± 0.831
0.753PheTrp: 0.753 ± 0.566
0.753PheTyr: 0.753 ± 0.635
0.0PheXaa: 0.0 ± 0.0
Gly
11.295GlyAla: 11.295 ± 3.09
0.753GlyCys: 0.753 ± 0.633
5.271GlyAsp: 5.271 ± 2.556
2.259GlyGlu: 2.259 ± 1.033
3.765GlyPhe: 3.765 ± 1.253
11.295GlyGly: 11.295 ± 1.049
1.506GlyHis: 1.506 ± 0.854
4.518GlyIle: 4.518 ± 0.988
3.765GlyLys: 3.765 ± 1.82
6.024GlyLeu: 6.024 ± 1.679
2.259GlyMet: 2.259 ± 0.928
1.506GlyAsn: 1.506 ± 1.271
3.765GlyPro: 3.765 ± 1.701
2.259GlyGln: 2.259 ± 1.217
6.024GlyArg: 6.024 ± 4.505
3.765GlySer: 3.765 ± 1.366
4.518GlyThr: 4.518 ± 1.131
2.259GlyVal: 2.259 ± 0.928
0.753GlyTrp: 0.753 ± 0.635
1.506GlyTyr: 1.506 ± 0.643
0.0GlyXaa: 0.0 ± 0.0
His
1.506HisAla: 1.506 ± 1.841
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.753HisGlu: 0.753 ± 0.633
0.0HisPhe: 0.0 ± 0.0
3.012HisGly: 3.012 ± 1.005
0.753HisHis: 0.753 ± 0.566
0.753HisIle: 0.753 ± 0.633
0.0HisLys: 0.0 ± 0.0
1.506HisLeu: 1.506 ± 1.271
0.753HisMet: 0.753 ± 0.566
0.753HisAsn: 0.753 ± 0.633
4.518HisPro: 4.518 ± 1.108
0.0HisGln: 0.0 ± 0.0
1.506HisArg: 1.506 ± 0.643
3.012HisSer: 3.012 ± 1.554
0.0HisThr: 0.0 ± 0.0
2.259HisVal: 2.259 ± 1.033
1.506HisTrp: 1.506 ± 1.131
1.506HisTyr: 1.506 ± 0.643
0.0HisXaa: 0.0 ± 0.0
Ile
2.259IleAla: 2.259 ± 1.033
0.0IleCys: 0.0 ± 0.0
0.753IleAsp: 0.753 ± 0.921
2.259IleGlu: 2.259 ± 0.891
2.259IlePhe: 2.259 ± 0.928
6.024IleGly: 6.024 ± 0.987
3.012IleHis: 3.012 ± 0.664
1.506IleIle: 1.506 ± 0.733
1.506IleLys: 1.506 ± 0.854
0.753IleLeu: 0.753 ± 0.635
0.0IleMet: 0.0 ± 0.0
3.765IleAsn: 3.765 ± 1.124
2.259IlePro: 2.259 ± 1.033
3.765IleGln: 3.765 ± 2.072
5.271IleArg: 5.271 ± 1.19
2.259IleSer: 2.259 ± 1.055
3.765IleThr: 3.765 ± 0.71
2.259IleVal: 2.259 ± 0.928
0.753IleTrp: 0.753 ± 0.633
2.259IleTyr: 2.259 ± 1.145
0.0IleXaa: 0.0 ± 0.0
Lys
2.259LysAla: 2.259 ± 1.518
1.506LysCys: 1.506 ± 1.267
0.753LysAsp: 0.753 ± 0.566
6.777LysGlu: 6.777 ± 1.012
2.259LysPhe: 2.259 ± 1.145
4.518LysGly: 4.518 ± 0.748
0.753LysHis: 0.753 ± 0.566
7.53LysIle: 7.53 ± 1.243
8.283LysLys: 8.283 ± 3.979
3.765LysLeu: 3.765 ± 0.946
2.259LysMet: 2.259 ± 1.214
0.753LysAsn: 0.753 ± 0.635
5.271LysPro: 5.271 ± 1.448
2.259LysGln: 2.259 ± 1.518
2.259LysArg: 2.259 ± 0.802
6.024LysSer: 6.024 ± 2.595
2.259LysThr: 2.259 ± 1.547
2.259LysVal: 2.259 ± 1.214
0.753LysTrp: 0.753 ± 0.635
3.765LysTyr: 3.765 ± 1.561
0.0LysXaa: 0.0 ± 0.0
Leu
8.283LeuAla: 8.283 ± 1.086
0.753LeuCys: 0.753 ± 0.633
4.518LeuAsp: 4.518 ± 1.468
6.024LeuGlu: 6.024 ± 1.329
0.0LeuPhe: 0.0 ± 0.0
4.518LeuGly: 4.518 ± 1.678
0.753LeuHis: 0.753 ± 0.635
2.259LeuIle: 2.259 ± 1.145
5.271LeuLys: 5.271 ± 1.067
5.271LeuLeu: 5.271 ± 1.105
2.259LeuMet: 2.259 ± 0.813
3.765LeuAsn: 3.765 ± 1.017
5.271LeuPro: 5.271 ± 2.099
5.271LeuGln: 5.271 ± 0.567
6.024LeuArg: 6.024 ± 0.987
2.259LeuSer: 2.259 ± 0.374
3.765LeuThr: 3.765 ± 1.017
5.271LeuVal: 5.271 ± 0.851
1.506LeuTrp: 1.506 ± 0.643
0.753LeuTyr: 0.753 ± 0.633
0.0LeuXaa: 0.0 ± 0.0
Met
3.765MetAla: 3.765 ± 0.946
0.0MetCys: 0.0 ± 0.0
2.259MetAsp: 2.259 ± 0.928
2.259MetGlu: 2.259 ± 1.217
0.753MetPhe: 0.753 ± 0.566
2.259MetGly: 2.259 ± 1.055
0.753MetHis: 0.753 ± 0.566
1.506MetIle: 1.506 ± 1.131
2.259MetLys: 2.259 ± 1.119
3.012MetLeu: 3.012 ± 0.82
0.0MetMet: 0.0 ± 0.0
0.753MetAsn: 0.753 ± 0.635
1.506MetPro: 1.506 ± 0.733
0.0MetGln: 0.0 ± 0.0
1.506MetArg: 1.506 ± 0.559
2.259MetSer: 2.259 ± 1.033
0.753MetThr: 0.753 ± 0.633
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
6.024AsnAla: 6.024 ± 4.15
0.0AsnCys: 0.0 ± 0.0
4.518AsnAsp: 4.518 ± 1.669
3.012AsnGlu: 3.012 ± 0.664
0.753AsnPhe: 0.753 ± 0.635
3.765AsnGly: 3.765 ± 1.02
0.0AsnHis: 0.0 ± 0.0
2.259AsnIle: 2.259 ± 1.217
0.753AsnLys: 0.753 ± 0.566
2.259AsnLeu: 2.259 ± 1.697
1.506AsnMet: 1.506 ± 0.559
0.753AsnAsn: 0.753 ± 0.635
3.012AsnPro: 3.012 ± 0.82
1.506AsnGln: 1.506 ± 0.559
3.012AsnArg: 3.012 ± 1.649
3.012AsnSer: 3.012 ± 1.463
2.259AsnThr: 2.259 ± 1.697
2.259AsnVal: 2.259 ± 0.802
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.012ProAla: 3.012 ± 2.06
0.753ProCys: 0.753 ± 0.633
1.506ProAsp: 1.506 ± 0.854
4.518ProGlu: 4.518 ± 1.563
3.765ProPhe: 3.765 ± 0.839
4.518ProGly: 4.518 ± 1.131
2.259ProHis: 2.259 ± 0.891
5.271ProIle: 5.271 ± 2.225
3.765ProLys: 3.765 ± 1.953
3.765ProLeu: 3.765 ± 1.907
2.259ProMet: 2.259 ± 0.928
0.0ProAsn: 0.0 ± 0.0
3.012ProPro: 3.012 ± 1.467
0.753ProGln: 0.753 ± 0.635
0.0ProArg: 0.0 ± 0.0
8.283ProSer: 8.283 ± 4.91
6.024ProThr: 6.024 ± 2.266
4.518ProVal: 4.518 ± 1.63
1.506ProTrp: 1.506 ± 0.854
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.012GlnAla: 3.012 ± 0.869
0.753GlnCys: 0.753 ± 0.633
2.259GlnAsp: 2.259 ± 0.374
0.753GlnGlu: 0.753 ± 0.921
0.753GlnPhe: 0.753 ± 0.566
2.259GlnGly: 2.259 ± 0.374
0.753GlnHis: 0.753 ± 0.566
0.753GlnIle: 0.753 ± 0.635
6.777GlnLys: 6.777 ± 2.216
3.765GlnLeu: 3.765 ± 3.177
0.0GlnMet: 0.0 ± 0.0
5.271GlnAsn: 5.271 ± 2.893
1.506GlnPro: 1.506 ± 1.131
2.259GlnGln: 2.259 ± 1.217
2.259GlnArg: 2.259 ± 1.033
1.506GlnSer: 1.506 ± 0.733
1.506GlnThr: 1.506 ± 0.559
0.0GlnVal: 0.0 ± 0.0
0.753GlnTrp: 0.753 ± 0.635
0.753GlnTyr: 0.753 ± 0.633
0.0GlnXaa: 0.0 ± 0.0
Arg
6.777ArgAla: 6.777 ± 2.029
0.0ArgCys: 0.0 ± 0.0
4.518ArgAsp: 4.518 ± 1.483
2.259ArgGlu: 2.259 ± 0.374
1.506ArgPhe: 1.506 ± 0.854
0.0ArgGly: 0.0 ± 0.0
1.506ArgHis: 1.506 ± 1.131
2.259ArgIle: 2.259 ± 1.145
5.271ArgLys: 5.271 ± 2.617
6.024ArgLeu: 6.024 ± 1.871
0.753ArgMet: 0.753 ± 0.566
3.012ArgAsn: 3.012 ± 0.664
3.765ArgPro: 3.765 ± 0.495
1.506ArgGln: 1.506 ± 0.733
4.518ArgArg: 4.518 ± 2.289
3.765ArgSer: 3.765 ± 1.746
7.53ArgThr: 7.53 ± 1.705
0.0ArgVal: 0.0 ± 0.0
1.506ArgTrp: 1.506 ± 0.559
7.53ArgTyr: 7.53 ± 2.782
0.0ArgXaa: 0.0 ± 0.0
Ser
6.024SerAla: 6.024 ± 1.679
0.0SerCys: 0.0 ± 0.0
3.765SerAsp: 3.765 ± 1.531
2.259SerGlu: 2.259 ± 0.802
3.012SerPhe: 3.012 ± 1.005
6.777SerGly: 6.777 ± 1.799
3.012SerHis: 3.012 ± 0.664
1.506SerIle: 1.506 ± 0.643
4.518SerLys: 4.518 ± 2.531
4.518SerLeu: 4.518 ± 2.286
1.506SerMet: 1.506 ± 0.643
3.012SerAsn: 3.012 ± 1.118
2.259SerPro: 2.259 ± 0.374
3.012SerGln: 3.012 ± 1.467
3.012SerArg: 3.012 ± 0.618
3.012SerSer: 3.012 ± 0.664
6.777SerThr: 6.777 ± 1.265
3.012SerVal: 3.012 ± 1.432
0.0SerTrp: 0.0 ± 0.0
4.518SerTyr: 4.518 ± 1.197
0.0SerXaa: 0.0 ± 0.0
Thr
5.271ThrAla: 5.271 ± 0.567
0.753ThrCys: 0.753 ± 0.633
6.777ThrAsp: 6.777 ± 2.616
2.259ThrGlu: 2.259 ± 1.13
1.506ThrPhe: 1.506 ± 0.854
4.518ThrGly: 4.518 ± 2.621
3.012ThrHis: 3.012 ± 1.734
3.012ThrIle: 3.012 ± 0.618
5.271ThrLys: 5.271 ± 2.156
7.53ThrLeu: 7.53 ± 1.794
0.753ThrMet: 0.753 ± 0.635
0.753ThrAsn: 0.753 ± 0.566
4.518ThrPro: 4.518 ± 1.677
3.765ThrGln: 3.765 ± 1.419
1.506ThrArg: 1.506 ± 0.643
4.518ThrSer: 4.518 ± 1.857
4.518ThrThr: 4.518 ± 1.352
2.259ThrVal: 2.259 ± 1.697
1.506ThrTrp: 1.506 ± 1.267
0.753ThrTyr: 0.753 ± 0.633
0.0ThrXaa: 0.0 ± 0.0
Val
3.765ValAla: 3.765 ± 0.946
1.506ValCys: 1.506 ± 0.733
3.765ValAsp: 3.765 ± 0.495
3.012ValGlu: 3.012 ± 0.869
2.259ValPhe: 2.259 ± 1.697
3.765ValGly: 3.765 ± 1.366
0.0ValHis: 0.0 ± 0.0
0.753ValIle: 0.753 ± 0.635
1.506ValLys: 1.506 ± 1.131
3.012ValLeu: 3.012 ± 1.287
1.506ValMet: 1.506 ± 1.131
2.259ValAsn: 2.259 ± 0.928
6.024ValPro: 6.024 ± 1.672
1.506ValGln: 1.506 ± 0.559
1.506ValArg: 1.506 ± 1.104
5.271ValSer: 5.271 ± 2.347
3.765ValThr: 3.765 ± 1.483
2.259ValVal: 2.259 ± 0.928
0.753ValTrp: 0.753 ± 0.635
3.012ValTyr: 3.012 ± 1.432
0.0ValXaa: 0.0 ± 0.0
Trp
1.506TrpAla: 1.506 ± 0.559
0.0TrpCys: 0.0 ± 0.0
1.506TrpAsp: 1.506 ± 1.131
1.506TrpGlu: 1.506 ± 0.643
1.506TrpPhe: 1.506 ± 1.131
0.0TrpGly: 0.0 ± 0.0
0.753TrpHis: 0.753 ± 0.566
0.0TrpIle: 0.0 ± 0.0
1.506TrpLys: 1.506 ± 1.271
0.753TrpLeu: 0.753 ± 0.633
0.0TrpMet: 0.0 ± 0.0
0.753TrpAsn: 0.753 ± 0.635
0.0TrpPro: 0.0 ± 0.0
1.506TrpGln: 1.506 ± 0.854
0.0TrpArg: 0.0 ± 0.0
0.753TrpSer: 0.753 ± 0.633
0.753TrpThr: 0.753 ± 0.633
0.753TrpVal: 0.753 ± 0.635
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.765TyrAla: 3.765 ± 1.425
0.0TyrCys: 0.0 ± 0.0
0.753TyrAsp: 0.753 ± 0.633
1.506TyrGlu: 1.506 ± 1.104
1.506TyrPhe: 1.506 ± 1.131
4.518TyrGly: 4.518 ± 2.289
0.753TyrHis: 0.753 ± 0.633
0.753TyrIle: 0.753 ± 0.566
0.753TyrLys: 0.753 ± 0.566
3.012TyrLeu: 3.012 ± 1.536
2.259TyrMet: 2.259 ± 1.033
1.506TyrAsn: 1.506 ± 0.559
1.506TyrPro: 1.506 ± 0.559
2.259TyrGln: 2.259 ± 1.907
3.765TyrArg: 3.765 ± 2.072
1.506TyrSer: 1.506 ± 1.267
1.506TyrThr: 1.506 ± 1.131
3.012TyrVal: 3.012 ± 1.734
0.753TyrTrp: 0.753 ± 0.566
2.259TyrTyr: 2.259 ± 1.9
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1329 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski