Amino acid dipepetide frequency for Equine adenovirus A serotype 1 (EAdV-1) (Equine adenovirus 1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.169AlaAla: 13.169 ± 1.816
1.816AlaCys: 1.816 ± 0.491
4.45AlaAsp: 4.45 ± 0.672
5.631AlaGlu: 5.631 ± 0.796
4.995AlaPhe: 4.995 ± 0.62
7.175AlaGly: 7.175 ± 0.892
1.998AlaHis: 1.998 ± 0.377
2.906AlaIle: 2.906 ± 0.47
2.543AlaLys: 2.543 ± 0.596
8.9AlaLeu: 8.9 ± 1.123
1.362AlaMet: 1.362 ± 0.374
2.906AlaAsn: 2.906 ± 0.856
6.63AlaPro: 6.63 ± 0.919
2.997AlaGln: 2.997 ± 0.577
6.085AlaArg: 6.085 ± 1.088
6.357AlaSer: 6.357 ± 0.956
4.45AlaThr: 4.45 ± 0.661
7.901AlaVal: 7.901 ± 0.768
0.817AlaTrp: 0.817 ± 0.241
1.907AlaTyr: 1.907 ± 0.403
0.0AlaXaa: 0.0 ± 0.0
Cys
0.908CysAla: 0.908 ± 0.326
0.908CysCys: 0.908 ± 0.305
0.545CysAsp: 0.545 ± 0.156
0.817CysGlu: 0.817 ± 0.225
1.453CysPhe: 1.453 ± 0.425
1.544CysGly: 1.544 ± 0.423
0.091CysHis: 0.091 ± 0.096
0.636CysIle: 0.636 ± 0.211
0.545CysLys: 0.545 ± 0.184
2.543CysLeu: 2.543 ± 0.494
0.727CysMet: 0.727 ± 0.252
0.545CysAsn: 0.545 ± 0.277
1.181CysPro: 1.181 ± 0.337
0.454CysGln: 0.454 ± 0.167
1.453CysArg: 1.453 ± 0.343
0.727CysSer: 0.727 ± 0.259
0.999CysThr: 0.999 ± 0.264
0.999CysVal: 0.999 ± 0.339
0.272CysTrp: 0.272 ± 0.128
0.908CysTyr: 0.908 ± 0.333
0.0CysXaa: 0.0 ± 0.0
Asp
3.542AspAla: 3.542 ± 0.526
0.545AspCys: 0.545 ± 0.189
1.907AspAsp: 1.907 ± 0.494
3.724AspGlu: 3.724 ± 0.679
1.907AspPhe: 1.907 ± 0.521
2.543AspGly: 2.543 ± 0.488
1.181AspHis: 1.181 ± 0.295
2.361AspIle: 2.361 ± 0.447
0.908AspLys: 0.908 ± 0.34
4.359AspLeu: 4.359 ± 0.611
0.908AspMet: 0.908 ± 0.361
1.544AspAsn: 1.544 ± 0.438
3.724AspPro: 3.724 ± 0.456
1.544AspGln: 1.544 ± 0.395
2.906AspArg: 2.906 ± 0.492
4.268AspSer: 4.268 ± 0.551
2.452AspThr: 2.452 ± 0.475
3.542AspVal: 3.542 ± 0.478
0.363AspTrp: 0.363 ± 0.141
1.544AspTyr: 1.544 ± 0.402
0.0AspXaa: 0.0 ± 0.0
Glu
5.449GluAla: 5.449 ± 0.936
1.09GluCys: 1.09 ± 0.296
4.268GluAsp: 4.268 ± 0.762
7.175GluGlu: 7.175 ± 1.691
1.544GluPhe: 1.544 ± 0.284
5.086GluGly: 5.086 ± 0.921
0.908GluHis: 0.908 ± 0.263
1.816GluIle: 1.816 ± 0.415
1.998GluLys: 1.998 ± 0.475
4.904GluLeu: 4.904 ± 0.79
1.09GluMet: 1.09 ± 0.392
2.361GluAsn: 2.361 ± 0.558
3.179GluPro: 3.179 ± 0.488
1.726GluGln: 1.726 ± 0.43
4.087GluArg: 4.087 ± 0.789
3.633GluSer: 3.633 ± 0.753
3.36GluThr: 3.36 ± 0.667
4.359GluVal: 4.359 ± 0.681
0.727GluTrp: 0.727 ± 0.294
1.271GluTyr: 1.271 ± 0.286
0.0GluXaa: 0.0 ± 0.0
Phe
3.088PheAla: 3.088 ± 0.634
0.727PheCys: 0.727 ± 0.304
2.18PheAsp: 2.18 ± 0.412
2.361PheGlu: 2.361 ± 0.615
2.18PhePhe: 2.18 ± 0.553
1.907PheGly: 1.907 ± 0.478
0.817PheHis: 0.817 ± 0.238
1.816PheIle: 1.816 ± 0.38
1.181PheLys: 1.181 ± 0.299
3.996PheLeu: 3.996 ± 0.86
1.544PheMet: 1.544 ± 0.255
1.816PheAsn: 1.816 ± 0.358
1.816PhePro: 1.816 ± 0.331
1.998PheGln: 1.998 ± 0.47
2.634PheArg: 2.634 ± 0.572
3.088PheSer: 3.088 ± 0.79
2.27PheThr: 2.27 ± 0.379
3.269PheVal: 3.269 ± 0.504
0.091PheTrp: 0.091 ± 0.095
1.907PheTyr: 1.907 ± 0.339
0.0PheXaa: 0.0 ± 0.0
Gly
6.902GlyAla: 6.902 ± 1.219
1.09GlyCys: 1.09 ± 0.32
3.179GlyAsp: 3.179 ± 0.642
3.996GlyGlu: 3.996 ± 0.874
1.998GlyPhe: 1.998 ± 0.508
7.72GlyGly: 7.72 ± 1.484
1.453GlyHis: 1.453 ± 0.408
1.907GlyIle: 1.907 ± 0.558
1.544GlyLys: 1.544 ± 0.346
8.537GlyLeu: 8.537 ± 2.509
1.181GlyMet: 1.181 ± 0.319
3.179GlyAsn: 3.179 ± 0.905
4.813GlyPro: 4.813 ± 0.84
2.543GlyGln: 2.543 ± 0.661
5.54GlyArg: 5.54 ± 0.682
4.632GlySer: 4.632 ± 0.748
3.542GlyThr: 3.542 ± 0.581
4.904GlyVal: 4.904 ± 0.629
0.999GlyTrp: 0.999 ± 0.313
1.544GlyTyr: 1.544 ± 0.345
0.0GlyXaa: 0.0 ± 0.0
His
2.452HisAla: 2.452 ± 0.686
0.817HisCys: 0.817 ± 0.255
0.545HisAsp: 0.545 ± 0.199
1.181HisGlu: 1.181 ± 0.264
0.727HisPhe: 0.727 ± 0.231
2.543HisGly: 2.543 ± 0.391
1.09HisHis: 1.09 ± 0.417
1.181HisIle: 1.181 ± 0.299
0.727HisLys: 0.727 ± 0.337
2.634HisLeu: 2.634 ± 0.456
0.363HisMet: 0.363 ± 0.163
1.09HisAsn: 1.09 ± 0.434
2.452HisPro: 2.452 ± 0.548
0.817HisGln: 0.817 ± 0.291
1.907HisArg: 1.907 ± 0.424
1.816HisSer: 1.816 ± 0.417
1.271HisThr: 1.271 ± 0.392
0.817HisVal: 0.817 ± 0.266
0.545HisTrp: 0.545 ± 0.244
1.271HisTyr: 1.271 ± 0.29
0.0HisXaa: 0.0 ± 0.0
Ile
3.451IleAla: 3.451 ± 0.469
0.908IleCys: 0.908 ± 0.321
1.726IleAsp: 1.726 ± 0.34
1.362IleGlu: 1.362 ± 0.349
1.181IlePhe: 1.181 ± 0.29
2.089IleGly: 2.089 ± 0.479
0.908IleHis: 0.908 ± 0.252
1.09IleIle: 1.09 ± 0.324
1.816IleLys: 1.816 ± 0.41
3.542IleLeu: 3.542 ± 0.546
0.727IleMet: 0.727 ± 0.186
1.635IleAsn: 1.635 ± 0.309
2.18IlePro: 2.18 ± 0.524
1.453IleGln: 1.453 ± 0.388
3.269IleArg: 3.269 ± 0.651
2.997IleSer: 2.997 ± 0.449
2.18IleThr: 2.18 ± 0.332
1.362IleVal: 1.362 ± 0.378
0.363IleTrp: 0.363 ± 0.223
0.545IleTyr: 0.545 ± 0.202
0.0IleXaa: 0.0 ± 0.0
Lys
2.18LysAla: 2.18 ± 0.618
0.363LysCys: 0.363 ± 0.183
1.635LysAsp: 1.635 ± 0.404
1.453LysGlu: 1.453 ± 0.376
1.181LysPhe: 1.181 ± 0.288
1.907LysGly: 1.907 ± 0.407
0.454LysHis: 0.454 ± 0.16
1.726LysIle: 1.726 ± 0.486
1.271LysLys: 1.271 ± 0.388
3.179LysLeu: 3.179 ± 0.574
0.454LysMet: 0.454 ± 0.2
1.271LysAsn: 1.271 ± 0.317
1.362LysPro: 1.362 ± 0.311
1.09LysGln: 1.09 ± 0.275
3.088LysArg: 3.088 ± 0.593
2.18LysSer: 2.18 ± 0.465
1.907LysThr: 1.907 ± 0.302
2.815LysVal: 2.815 ± 0.374
0.272LysTrp: 0.272 ± 0.117
0.636LysTyr: 0.636 ± 0.198
0.0LysXaa: 0.0 ± 0.0
Leu
7.265LeuAla: 7.265 ± 1.058
1.544LeuCys: 1.544 ± 0.444
3.633LeuAsp: 3.633 ± 0.49
5.54LeuGlu: 5.54 ± 0.741
3.724LeuPhe: 3.724 ± 0.581
5.812LeuGly: 5.812 ± 0.837
3.451LeuHis: 3.451 ± 0.665
2.361LeuIle: 2.361 ± 0.512
3.905LeuLys: 3.905 ± 0.649
8.719LeuLeu: 8.719 ± 0.931
2.361LeuMet: 2.361 ± 0.427
3.542LeuAsn: 3.542 ± 0.39
6.721LeuPro: 6.721 ± 0.778
5.722LeuGln: 5.722 ± 2.053
7.265LeuArg: 7.265 ± 0.937
7.356LeuSer: 7.356 ± 0.809
6.902LeuThr: 6.902 ± 0.942
5.267LeuVal: 5.267 ± 0.617
1.271LeuTrp: 1.271 ± 0.301
2.452LeuTyr: 2.452 ± 0.558
0.0LeuXaa: 0.0 ± 0.0
Met
1.998MetAla: 1.998 ± 0.494
0.363MetCys: 0.363 ± 0.16
1.271MetAsp: 1.271 ± 0.276
1.816MetGlu: 1.816 ± 0.442
0.363MetPhe: 0.363 ± 0.165
1.362MetGly: 1.362 ± 0.48
0.817MetHis: 0.817 ± 0.278
0.636MetIle: 0.636 ± 0.215
0.999MetLys: 0.999 ± 0.336
2.089MetLeu: 2.089 ± 0.429
0.454MetMet: 0.454 ± 0.207
1.362MetAsn: 1.362 ± 0.3
1.09MetPro: 1.09 ± 0.343
0.908MetGln: 0.908 ± 0.257
1.362MetArg: 1.362 ± 0.453
2.452MetSer: 2.452 ± 0.505
0.727MetThr: 0.727 ± 0.224
0.727MetVal: 0.727 ± 0.204
0.454MetTrp: 0.454 ± 0.176
0.817MetTyr: 0.817 ± 0.224
0.0MetXaa: 0.0 ± 0.0
Asn
2.997AsnAla: 2.997 ± 0.656
0.636AsnCys: 0.636 ± 0.246
1.181AsnAsp: 1.181 ± 0.408
1.998AsnGlu: 1.998 ± 0.35
2.27AsnPhe: 2.27 ± 0.429
2.725AsnGly: 2.725 ± 0.904
0.999AsnHis: 0.999 ± 0.324
2.18AsnIle: 2.18 ± 0.411
1.09AsnLys: 1.09 ± 0.321
3.179AsnLeu: 3.179 ± 0.739
1.453AsnMet: 1.453 ± 0.489
2.361AsnAsn: 2.361 ± 0.388
2.725AsnPro: 2.725 ± 0.412
1.09AsnGln: 1.09 ± 0.314
2.997AsnArg: 2.997 ± 0.546
2.725AsnSer: 2.725 ± 0.523
2.18AsnThr: 2.18 ± 0.423
2.997AsnVal: 2.997 ± 0.498
0.817AsnTrp: 0.817 ± 0.245
1.635AsnTyr: 1.635 ± 0.454
0.0AsnXaa: 0.0 ± 0.0
Pro
6.902ProAla: 6.902 ± 1.103
0.908ProCys: 0.908 ± 0.292
3.36ProAsp: 3.36 ± 0.499
5.358ProGlu: 5.358 ± 0.709
2.27ProPhe: 2.27 ± 0.48
4.359ProGly: 4.359 ± 1.193
2.18ProHis: 2.18 ± 0.887
1.181ProIle: 1.181 ± 0.271
1.544ProLys: 1.544 ± 0.427
6.357ProLeu: 6.357 ± 0.738
1.544ProMet: 1.544 ± 0.371
2.089ProAsn: 2.089 ± 0.479
6.357ProPro: 6.357 ± 0.918
3.179ProGln: 3.179 ± 0.516
4.359ProArg: 4.359 ± 0.72
4.45ProSer: 4.45 ± 0.925
3.996ProThr: 3.996 ± 0.574
4.359ProVal: 4.359 ± 0.716
0.545ProTrp: 0.545 ± 0.199
1.635ProTyr: 1.635 ± 0.492
0.0ProXaa: 0.0 ± 0.0
Gln
3.269GlnAla: 3.269 ± 0.445
0.454GlnCys: 0.454 ± 0.207
1.816GlnAsp: 1.816 ± 0.32
2.361GlnGlu: 2.361 ± 0.378
1.271GlnPhe: 1.271 ± 0.362
2.906GlnGly: 2.906 ± 0.537
1.453GlnHis: 1.453 ± 0.45
1.362GlnIle: 1.362 ± 0.357
1.271GlnLys: 1.271 ± 0.326
4.541GlnLeu: 4.541 ± 0.786
0.908GlnMet: 0.908 ± 0.29
1.816GlnAsn: 1.816 ± 0.448
2.543GlnPro: 2.543 ± 0.373
1.635GlnGln: 1.635 ± 0.366
3.269GlnArg: 3.269 ± 0.404
2.906GlnSer: 2.906 ± 0.514
2.634GlnThr: 2.634 ± 0.399
3.179GlnVal: 3.179 ± 1.06
0.454GlnTrp: 0.454 ± 0.186
0.817GlnTyr: 0.817 ± 0.33
0.0GlnXaa: 0.0 ± 0.0
Arg
8.537ArgAla: 8.537 ± 0.946
2.18ArgCys: 2.18 ± 0.56
2.906ArgAsp: 2.906 ± 0.516
3.451ArgGlu: 3.451 ± 0.739
2.543ArgPhe: 2.543 ± 0.435
6.448ArgGly: 6.448 ± 1.073
1.453ArgHis: 1.453 ± 0.413
2.815ArgIle: 2.815 ± 0.572
2.27ArgLys: 2.27 ± 0.422
7.81ArgLeu: 7.81 ± 0.836
1.362ArgMet: 1.362 ± 0.472
2.997ArgAsn: 2.997 ± 0.647
3.996ArgPro: 3.996 ± 0.825
2.725ArgGln: 2.725 ± 0.551
9.445ArgArg: 9.445 ± 1.982
4.723ArgSer: 4.723 ± 0.814
2.725ArgThr: 2.725 ± 0.7
4.632ArgVal: 4.632 ± 0.755
1.635ArgTrp: 1.635 ± 0.28
1.816ArgTyr: 1.816 ± 0.523
0.0ArgXaa: 0.0 ± 0.0
Ser
7.538SerAla: 7.538 ± 0.968
0.908SerCys: 0.908 ± 0.327
3.36SerAsp: 3.36 ± 0.689
3.633SerGlu: 3.633 ± 0.778
3.542SerPhe: 3.542 ± 0.614
5.631SerGly: 5.631 ± 0.995
2.18SerHis: 2.18 ± 0.372
2.543SerIle: 2.543 ± 0.633
2.27SerLys: 2.27 ± 0.484
6.539SerLeu: 6.539 ± 0.899
1.181SerMet: 1.181 ± 0.313
2.452SerAsn: 2.452 ± 0.465
4.813SerPro: 4.813 ± 1.103
2.997SerGln: 2.997 ± 0.396
5.267SerArg: 5.267 ± 1.119
5.358SerSer: 5.358 ± 0.814
2.18SerThr: 2.18 ± 0.407
5.086SerVal: 5.086 ± 0.748
1.362SerTrp: 1.362 ± 0.289
3.269SerTyr: 3.269 ± 0.535
0.0SerXaa: 0.0 ± 0.0
Thr
5.54ThrAla: 5.54 ± 0.622
1.181ThrCys: 1.181 ± 0.27
2.543ThrAsp: 2.543 ± 0.508
2.361ThrGlu: 2.361 ± 0.505
2.452ThrPhe: 2.452 ± 0.474
3.451ThrGly: 3.451 ± 0.863
1.726ThrHis: 1.726 ± 0.323
2.543ThrIle: 2.543 ± 0.537
0.908ThrLys: 0.908 ± 0.228
4.632ThrLeu: 4.632 ± 0.531
0.817ThrMet: 0.817 ± 0.183
1.726ThrAsn: 1.726 ± 0.4
4.632ThrPro: 4.632 ± 0.655
2.18ThrGln: 2.18 ± 0.513
3.905ThrArg: 3.905 ± 0.653
3.269ThrSer: 3.269 ± 0.539
2.634ThrThr: 2.634 ± 0.425
3.996ThrVal: 3.996 ± 0.54
0.817ThrTrp: 0.817 ± 0.313
1.453ThrTyr: 1.453 ± 0.433
0.0ThrXaa: 0.0 ± 0.0
Val
6.811ValAla: 6.811 ± 0.833
1.09ValCys: 1.09 ± 0.302
3.088ValAsp: 3.088 ± 0.593
3.633ValGlu: 3.633 ± 0.705
3.179ValPhe: 3.179 ± 0.61
3.451ValGly: 3.451 ± 0.635
1.544ValHis: 1.544 ± 0.376
2.452ValIle: 2.452 ± 0.372
2.725ValLys: 2.725 ± 0.556
4.541ValLeu: 4.541 ± 0.542
1.726ValMet: 1.726 ± 0.471
3.633ValAsn: 3.633 ± 0.632
4.541ValPro: 4.541 ± 0.506
3.179ValGln: 3.179 ± 0.515
4.45ValArg: 4.45 ± 0.67
5.177ValSer: 5.177 ± 0.863
4.087ValThr: 4.087 ± 0.715
5.903ValVal: 5.903 ± 0.729
0.182ValTrp: 0.182 ± 0.117
3.179ValTyr: 3.179 ± 0.641
0.0ValXaa: 0.0 ± 0.0
Trp
0.817TrpAla: 0.817 ± 0.219
0.0TrpCys: 0.0 ± 0.0
0.817TrpAsp: 0.817 ± 0.228
0.363TrpGlu: 0.363 ± 0.213
0.182TrpPhe: 0.182 ± 0.121
1.362TrpGly: 1.362 ± 0.308
0.182TrpHis: 0.182 ± 0.117
0.363TrpIle: 0.363 ± 0.194
0.272TrpLys: 0.272 ± 0.173
1.09TrpLeu: 1.09 ± 0.281
0.363TrpMet: 0.363 ± 0.155
0.545TrpAsn: 0.545 ± 0.23
0.817TrpPro: 0.817 ± 0.229
1.09TrpGln: 1.09 ± 0.357
0.908TrpArg: 0.908 ± 0.321
1.453TrpSer: 1.453 ± 0.345
0.727TrpThr: 0.727 ± 0.231
0.454TrpVal: 0.454 ± 0.203
0.091TrpTrp: 0.091 ± 0.077
0.636TrpTyr: 0.636 ± 0.256
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.18TyrAla: 2.18 ± 0.569
0.727TyrCys: 0.727 ± 0.208
1.362TyrAsp: 1.362 ± 0.394
1.816TyrGlu: 1.816 ± 0.431
1.726TyrPhe: 1.726 ± 0.345
1.181TyrGly: 1.181 ± 0.286
1.362TyrHis: 1.362 ± 0.411
0.908TyrIle: 0.908 ± 0.31
0.727TyrLys: 0.727 ± 0.28
2.725TyrLeu: 2.725 ± 0.617
1.453TyrMet: 1.453 ± 0.262
1.362TyrAsn: 1.362 ± 0.391
1.362TyrPro: 1.362 ± 0.345
1.544TyrGln: 1.544 ± 0.353
2.27TyrArg: 2.27 ± 0.51
2.543TyrSer: 2.543 ± 0.569
1.544TyrThr: 1.544 ± 0.344
1.998TyrVal: 1.998 ± 0.446
0.454TyrTrp: 0.454 ± 0.242
0.999TyrTyr: 0.999 ± 0.223
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 31 proteins (11012 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski