Amino acid dipepetide frequency for Burkholderia plantarii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.21AlaAla: 22.21 ± 0.17	1.421AlaCys: 1.421 ± 0.03	7.192AlaAsp: 7.192 ± 0.064	6.3AlaGlu: 6.3 ± 0.062	4.552AlaPhe: 4.552 ± 0.048	12.659AlaGly: 12.659 ± 0.105	2.938AlaHis: 2.938 ± 0.041	5.743AlaIle: 5.743 ± 0.053	3.081AlaLys: 3.081 ± 0.055	15.752AlaLeu: 15.752 ± 0.137	3.305AlaMet: 3.305 ± 0.044	3.165AlaAsn: 3.165 ± 0.041	7.51AlaPro: 7.51 ± 0.077	5.047AlaGln: 5.047 ± 0.052	11.671AlaArg: 11.671 ± 0.097	7.895AlaSer: 7.895 ± 0.073	6.846AlaThr: 6.846 ± 0.075	9.074AlaVal: 9.074 ± 0.074	1.89AlaTrp: 1.89 ± 0.034	2.722AlaTyr: 2.722 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	1.221CysAla: 1.221 ± 0.026	0.119CysCys: 0.119 ± 0.008	0.502CysAsp: 0.502 ± 0.014	0.515CysGlu: 0.515 ± 0.016	0.318CysPhe: 0.318 ± 0.012	0.916CysGly: 0.916 ± 0.021	0.253CysHis: 0.253 ± 0.011	0.334CysIle: 0.334 ± 0.014	0.162CysLys: 0.162 ± 0.01	0.85CysLeu: 0.85 ± 0.021	0.172CysMet: 0.172 ± 0.009	0.192CysAsn: 0.192 ± 0.009	0.445CysPro: 0.445 ± 0.015	0.194CysGln: 0.194 ± 0.009	0.702CysArg: 0.702 ± 0.022	0.464CysSer: 0.464 ± 0.013	0.437CysThr: 0.437 ± 0.015	0.766CysVal: 0.766 ± 0.018	0.128CysTrp: 0.128 ± 0.007	0.213CysTyr: 0.213 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	9.279AspAla: 9.279 ± 0.093	0.458AspCys: 0.458 ± 0.015	3.485AspAsp: 3.485 ± 0.049	3.405AspGlu: 3.405 ± 0.044	1.829AspPhe: 1.829 ± 0.033	5.491AspGly: 5.491 ± 0.056	1.221AspHis: 1.221 ± 0.025	2.102AspIle: 2.102 ± 0.031	1.207AspLys: 1.207 ± 0.025	5.173AspLeu: 5.173 ± 0.056	1.005AspMet: 1.005 ± 0.019	1.163AspAsn: 1.163 ± 0.026	3.207AspPro: 3.207 ± 0.036	1.465AspGln: 1.465 ± 0.033	3.565AspArg: 3.565 ± 0.049	2.343AspSer: 2.343 ± 0.031	2.974AspThr: 2.974 ± 0.047	4.064AspVal: 4.064 ± 0.046	0.967AspTrp: 0.967 ± 0.023	1.548AspTyr: 1.548 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	7.129GluAla: 7.129 ± 0.085	0.382GluCys: 0.382 ± 0.016	1.82GluAsp: 1.82 ± 0.034	1.76GluGlu: 1.76 ± 0.036	1.599GluPhe: 1.599 ± 0.029	2.966GluGly: 2.966 ± 0.041	1.399GluHis: 1.399 ± 0.028	2.733GluIle: 2.733 ± 0.04	1.305GluLys: 1.305 ± 0.028	5.324GluLeu: 5.324 ± 0.06	1.077GluMet: 1.077 ± 0.027	1.091GluAsn: 1.091 ± 0.023	2.763GluPro: 2.763 ± 0.038	2.228GluGln: 2.228 ± 0.033	5.141GluArg: 5.141 ± 0.069	2.296GluSer: 2.296 ± 0.034	2.655GluThr: 2.655 ± 0.032	3.422GluVal: 3.422 ± 0.038	0.672GluTrp: 0.672 ± 0.018	1.009GluTyr: 1.009 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	4.882PheAla: 4.882 ± 0.055	0.369PheCys: 0.369 ± 0.013	2.697PheAsp: 2.697 ± 0.037	2.014PheGlu: 2.014 ± 0.033	1.296PhePhe: 1.296 ± 0.026	3.693PheGly: 3.693 ± 0.05	0.786PheHis: 0.786 ± 0.017	1.337PheIle: 1.337 ± 0.024	0.728PheLys: 0.728 ± 0.021	2.76PheLeu: 2.76 ± 0.042	0.677PheMet: 0.677 ± 0.019	0.993PheAsn: 0.993 ± 0.024	1.558PhePro: 1.558 ± 0.029	0.93PheGln: 0.93 ± 0.023	2.135PheArg: 2.135 ± 0.041	2.148PheSer: 2.148 ± 0.034	1.812PheThr: 1.812 ± 0.034	3.178PheVal: 3.178 ± 0.039	0.453PheTrp: 0.453 ± 0.016	0.849PheTyr: 0.849 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	11.161GlyAla: 11.161 ± 0.085	0.887GlyCys: 0.887 ± 0.022	4.235GlyAsp: 4.235 ± 0.047	4.5GlyGlu: 4.5 ± 0.054	3.534GlyPhe: 3.534 ± 0.042	7.655GlyGly: 7.655 ± 0.099	1.962GlyHis: 1.962 ± 0.031	4.186GlyIle: 4.186 ± 0.05	2.624GlyLys: 2.624 ± 0.038	8.198GlyLeu: 8.198 ± 0.091	2.07GlyMet: 2.07 ± 0.034	2.255GlyAsn: 2.255 ± 0.052	3.204GlyPro: 3.204 ± 0.04	2.711GlyGln: 2.711 ± 0.04	6.3GlyArg: 6.3 ± 0.065	4.675GlySer: 4.675 ± 0.069	4.986GlyThr: 4.986 ± 0.1	6.597GlyVal: 6.597 ± 0.064	1.514GlyTrp: 1.514 ± 0.031	2.501GlyTyr: 2.501 ± 0.038	0.0GlyXaa: 0.0 ± 0.0
His	3.516HisAla: 3.516 ± 0.045	0.259HisCys: 0.259 ± 0.01	1.572HisAsp: 1.572 ± 0.027	1.224HisGlu: 1.224 ± 0.025	0.925HisPhe: 0.925 ± 0.02	2.443HisGly: 2.443 ± 0.037	0.675HisHis: 0.675 ± 0.021	0.706HisIle: 0.706 ± 0.017	0.369HisLys: 0.369 ± 0.013	2.207HisLeu: 2.207 ± 0.034	0.413HisMet: 0.413 ± 0.014	0.445HisAsn: 0.445 ± 0.015	1.503HisPro: 1.503 ± 0.03	0.634HisGln: 0.634 ± 0.017	1.766HisArg: 1.766 ± 0.035	0.967HisSer: 0.967 ± 0.021	1.018HisThr: 1.018 ± 0.023	1.683HisVal: 1.683 ± 0.029	0.4HisTrp: 0.4 ± 0.014	0.68HisTyr: 0.68 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.772IleAla: 6.772 ± 0.056	0.385IleCys: 0.385 ± 0.014	3.44IleAsp: 3.44 ± 0.034	3.028IleGlu: 3.028 ± 0.036	1.14IlePhe: 1.14 ± 0.027	4.699IleGly: 4.699 ± 0.056	0.916IleHis: 0.916 ± 0.022	1.236IleIle: 1.236 ± 0.029	0.996IleLys: 0.996 ± 0.025	3.002IleLeu: 3.002 ± 0.045	0.606IleMet: 0.606 ± 0.016	1.188IleAsn: 1.188 ± 0.023	1.856IlePro: 1.856 ± 0.034	1.077IleGln: 1.077 ± 0.025	2.864IleArg: 2.864 ± 0.034	2.14IleSer: 2.14 ± 0.037	2.175IleThr: 2.175 ± 0.039	4.12IleVal: 4.12 ± 0.053	0.482IleTrp: 0.482 ± 0.016	0.923IleTyr: 0.923 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	2.902LysAla: 2.902 ± 0.049	0.136LysCys: 0.136 ± 0.008	1.123LysAsp: 1.123 ± 0.026	0.976LysGlu: 0.976 ± 0.031	0.732LysPhe: 0.732 ± 0.017	1.662LysGly: 1.662 ± 0.032	0.512LysHis: 0.512 ± 0.016	1.229LysIle: 1.229 ± 0.027	0.843LysLys: 0.843 ± 0.027	2.808LysLeu: 2.808 ± 0.043	0.585LysMet: 0.585 ± 0.017	0.628LysAsn: 0.628 ± 0.018	1.689LysPro: 1.689 ± 0.031	0.999LysGln: 0.999 ± 0.023	1.955LysArg: 1.955 ± 0.034	1.352LysSer: 1.352 ± 0.028	1.472LysThr: 1.472 ± 0.029	1.785LysVal: 1.785 ± 0.031	0.295LysTrp: 0.295 ± 0.01	0.573LysTyr: 0.573 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	16.04LeuAla: 16.04 ± 0.111	0.93LeuCys: 0.93 ± 0.023	6.814LeuAsp: 6.814 ± 0.064	4.571LeuGlu: 4.571 ± 0.053	3.451LeuPhe: 3.451 ± 0.052	8.682LeuGly: 8.682 ± 0.08	2.288LeuHis: 2.288 ± 0.035	4.199LeuIle: 4.199 ± 0.055	2.731LeuLys: 2.731 ± 0.04	10.024LeuLeu: 10.024 ± 0.093	2.058LeuMet: 2.058 ± 0.034	2.476LeuAsn: 2.476 ± 0.043	6.208LeuPro: 6.208 ± 0.068	3.028LeuGln: 3.028 ± 0.038	7.63LeuArg: 7.63 ± 0.074	6.037LeuSer: 6.037 ± 0.17	5.399LeuThr: 5.399 ± 0.058	7.662LeuVal: 7.662 ± 0.076	1.089LeuTrp: 1.089 ± 0.025	2.134LeuTyr: 2.134 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.311MetAla: 2.311 ± 0.037	0.148MetCys: 0.148 ± 0.007	0.821MetAsp: 0.821 ± 0.02	0.756MetGlu: 0.756 ± 0.019	0.69MetPhe: 0.69 ± 0.018	1.282MetGly: 1.282 ± 0.026	0.522MetHis: 0.522 ± 0.013	0.996MetIle: 0.996 ± 0.023	0.849MetLys: 0.849 ± 0.02	2.508MetLeu: 2.508 ± 0.036	0.524MetMet: 0.524 ± 0.018	0.776MetAsn: 0.776 ± 0.02	1.436MetPro: 1.436 ± 0.029	0.872MetGln: 0.872 ± 0.022	1.781MetArg: 1.781 ± 0.032	1.626MetSer: 1.626 ± 0.027	1.548MetThr: 1.548 ± 0.028	1.316MetVal: 1.316 ± 0.029	0.178MetTrp: 0.178 ± 0.009	0.345MetTyr: 0.345 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.26AsnAla: 3.26 ± 0.045	0.224AsnCys: 0.224 ± 0.01	1.328AsnAsp: 1.328 ± 0.029	1.053AsnGlu: 1.053 ± 0.024	0.87AsnPhe: 0.87 ± 0.024	2.432AsnGly: 2.432 ± 0.053	0.555AsnHis: 0.555 ± 0.016	0.954AsnIle: 0.954 ± 0.027	0.463AsnLys: 0.463 ± 0.015	2.65AsnLeu: 2.65 ± 0.038	0.451AsnMet: 0.451 ± 0.014	0.682AsnAsn: 0.682 ± 0.023	1.683AsnPro: 1.683 ± 0.028	0.82AsnGln: 0.82 ± 0.022	1.771AsnArg: 1.771 ± 0.03	1.191AsnSer: 1.191 ± 0.065	1.303AsnThr: 1.303 ± 0.03	2.022AsnVal: 2.022 ± 0.053	0.37AsnTrp: 0.37 ± 0.013	0.641AsnTyr: 0.641 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	8.557ProAla: 8.557 ± 0.093	0.376ProCys: 0.376 ± 0.013	3.731ProAsp: 3.731 ± 0.042	2.88ProGlu: 2.88 ± 0.041	1.963ProPhe: 1.963 ± 0.034	4.818ProGly: 4.818 ± 0.048	1.315ProHis: 1.315 ± 0.026	1.957ProIle: 1.957 ± 0.032	1.233ProLys: 1.233 ± 0.025	5.432ProLeu: 5.432 ± 0.058	1.074ProMet: 1.074 ± 0.023	1.323ProAsn: 1.323 ± 0.026	3.104ProPro: 3.104 ± 0.05	1.641ProGln: 1.641 ± 0.027	3.606ProArg: 3.606 ± 0.047	2.9ProSer: 2.9 ± 0.039	2.531ProThr: 2.531 ± 0.036	4.433ProVal: 4.433 ± 0.045	0.674ProTrp: 0.674 ± 0.017	1.17ProTyr: 1.17 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.669GlnAla: 4.669 ± 0.064	0.237GlnCys: 0.237 ± 0.011	1.251GlnAsp: 1.251 ± 0.024	1.095GlnGlu: 1.095 ± 0.03	1.177GlnPhe: 1.177 ± 0.024	2.277GlnGly: 2.277 ± 0.033	0.833GlnHis: 0.833 ± 0.021	1.73GlnIle: 1.73 ± 0.029	0.817GlnLys: 0.817 ± 0.023	3.637GlnLeu: 3.637 ± 0.045	0.819GlnMet: 0.819 ± 0.019	0.779GlnAsn: 0.779 ± 0.023	2.064GlnPro: 2.064 ± 0.036	1.672GlnGln: 1.672 ± 0.038	2.815GlnArg: 2.815 ± 0.043	1.79GlnSer: 1.79 ± 0.035	1.749GlnThr: 1.749 ± 0.031	2.414GlnVal: 2.414 ± 0.039	0.519GlnTrp: 0.519 ± 0.016	0.862GlnTyr: 0.862 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	9.862ArgAla: 9.862 ± 0.088	0.651ArgCys: 0.651 ± 0.022	4.406ArgAsp: 4.406 ± 0.052	4.657ArgGlu: 4.657 ± 0.055	3.216ArgPhe: 3.216 ± 0.04	5.376ArgGly: 5.376 ± 0.059	2.341ArgHis: 2.341 ± 0.035	3.813ArgIle: 3.813 ± 0.043	1.693ArgLys: 1.693 ± 0.029	8.33ArgLeu: 8.33 ± 0.086	1.805ArgMet: 1.805 ± 0.033	1.781ArgAsn: 1.781 ± 0.028	3.732ArgPro: 3.732 ± 0.05	2.758ArgGln: 2.758 ± 0.034	6.81ArgArg: 6.81 ± 0.077	3.434ArgSer: 3.434 ± 0.035	3.494ArgThr: 3.494 ± 0.038	5.688ArgVal: 5.688 ± 0.06	1.142ArgTrp: 1.142 ± 0.026	2.189ArgTyr: 2.189 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.673SerAla: 6.673 ± 0.074	0.42SerCys: 0.42 ± 0.015	2.56SerAsp: 2.56 ± 0.035	2.178SerGlu: 2.178 ± 0.037	2.031SerPhe: 2.031 ± 0.033	5.309SerGly: 5.309 ± 0.073	1.173SerHis: 1.173 ± 0.024	2.502SerIle: 2.502 ± 0.036	1.252SerLys: 1.252 ± 0.027	5.833SerLeu: 5.833 ± 0.11	1.228SerMet: 1.228 ± 0.025	1.514SerAsn: 1.514 ± 0.051	2.965SerPro: 2.965 ± 0.042	1.659SerGln: 1.659 ± 0.029	3.911SerArg: 3.911 ± 0.043	3.367SerSer: 3.367 ± 0.163	3.235SerThr: 3.235 ± 0.175	4.091SerVal: 4.091 ± 0.064	0.706SerTrp: 0.706 ± 0.018	1.318SerTyr: 1.318 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	6.191ThrAla: 6.191 ± 0.069	0.382ThrCys: 0.382 ± 0.013	2.664ThrAsp: 2.664 ± 0.04	2.091ThrGlu: 2.091 ± 0.03	1.826ThrPhe: 1.826 ± 0.03	4.836ThrGly: 4.836 ± 0.081	1.258ThrHis: 1.258 ± 0.024	2.507ThrIle: 2.507 ± 0.037	1.045ThrLys: 1.045 ± 0.025	6.686ThrLeu: 6.686 ± 0.076	1.084ThrMet: 1.084 ± 0.022	1.306ThrAsn: 1.306 ± 0.059	3.671ThrPro: 3.671 ± 0.041	1.743ThrGln: 1.743 ± 0.035	3.955ThrArg: 3.955 ± 0.04	2.948ThrSer: 2.948 ± 0.097	2.991ThrThr: 2.991 ± 0.081	4.132ThrVal: 4.132 ± 0.054	0.616ThrTrp: 0.616 ± 0.016	1.145ThrTyr: 1.145 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	10.292ValAla: 10.292 ± 0.077	0.718ValCys: 0.718 ± 0.017	4.242ValAsp: 4.242 ± 0.04	4.163ValGlu: 4.163 ± 0.051	2.665ValPhe: 2.665 ± 0.035	5.63ValGly: 5.63 ± 0.063	1.479ValHis: 1.479 ± 0.026	3.447ValIle: 3.447 ± 0.041	2.06ValLys: 2.06 ± 0.035	7.622ValLeu: 7.622 ± 0.07	1.649ValMet: 1.649 ± 0.032	1.99ValAsn: 1.99 ± 0.031	4.209ValPro: 4.209 ± 0.055	2.195ValGln: 2.195 ± 0.039	5.297ValArg: 5.297 ± 0.048	4.445ValSer: 4.445 ± 0.06	4.512ValThr: 4.512 ± 0.057	6.061ValVal: 6.061 ± 0.06	0.898ValTrp: 0.898 ± 0.021	1.583ValTyr: 1.583 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.208TrpAla: 1.208 ± 0.026	0.146TrpCys: 0.146 ± 0.008	0.599TrpAsp: 0.599 ± 0.018	0.476TrpGlu: 0.476 ± 0.015	0.562TrpPhe: 0.562 ± 0.019	0.822TrpGly: 0.822 ± 0.02	0.441TrpHis: 0.441 ± 0.014	0.659TrpIle: 0.659 ± 0.016	0.348TrpLys: 0.348 ± 0.012	2.026TrpLeu: 2.026 ± 0.035	0.324TrpMet: 0.324 ± 0.014	0.401TrpAsn: 0.401 ± 0.013	0.684TrpPro: 0.684 ± 0.021	0.681TrpGln: 0.681 ± 0.019	1.413TrpArg: 1.413 ± 0.027	0.79TrpSer: 0.79 ± 0.019	0.672TrpThr: 0.672 ± 0.018	0.827TrpVal: 0.827 ± 0.02	0.217TrpTrp: 0.217 ± 0.011	0.298TrpTyr: 0.298 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.837TyrAla: 2.837 ± 0.038	0.251TyrCys: 0.251 ± 0.011	1.466TyrAsp: 1.466 ± 0.051	1.132TyrGlu: 1.132 ± 0.025	0.917TyrPhe: 0.917 ± 0.023	2.106TyrGly: 2.106 ± 0.032	0.537TyrHis: 0.537 ± 0.016	0.677TyrIle: 0.677 ± 0.018	0.45TyrLys: 0.45 ± 0.016	2.631TyrLeu: 2.631 ± 0.035	0.36TyrMet: 0.36 ± 0.014	0.576TyrAsn: 0.576 ± 0.019	1.228TyrPro: 1.228 ± 0.026	0.852TyrGln: 0.852 ± 0.024	2.088TyrArg: 2.088 ± 0.032	1.117TyrSer: 1.117 ± 0.023	1.269TyrThr: 1.269 ± 0.029	1.823TyrVal: 1.823 ± 0.034	0.386TyrTrp: 0.386 ± 0.013	0.625TyrTyr: 0.625 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6432 proteins (2225259 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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