Amino acid dipepetide frequency for Leptonychotes weddellii papillomavirus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.727AlaAla: 3.727 ± 0.95
1.242AlaCys: 1.242 ± 1.168
4.969AlaAsp: 4.969 ± 1.281
2.899AlaGlu: 2.899 ± 1.201
4.141AlaPhe: 4.141 ± 1.545
3.313AlaGly: 3.313 ± 1.461
0.414AlaHis: 0.414 ± 0.374
1.656AlaIle: 1.656 ± 0.643
2.899AlaLys: 2.899 ± 0.845
5.797AlaLeu: 5.797 ± 1.893
0.414AlaMet: 0.414 ± 0.354
0.828AlaAsn: 0.828 ± 0.647
4.141AlaPro: 4.141 ± 2.168
4.141AlaGln: 4.141 ± 1.032
2.899AlaArg: 2.899 ± 0.57
3.727AlaSer: 3.727 ± 1.046
3.313AlaThr: 3.313 ± 1.162
2.07AlaVal: 2.07 ± 0.691
0.828AlaTrp: 0.828 ± 0.668
0.414AlaTyr: 0.414 ± 0.334
0.0AlaXaa: 0.0 ± 0.0
Cys
1.656CysAla: 1.656 ± 1.01
1.656CysCys: 1.656 ± 0.936
0.414CysAsp: 0.414 ± 0.354
1.242CysGlu: 1.242 ± 0.717
2.484CysPhe: 2.484 ± 0.949
2.07CysGly: 2.07 ± 1.415
0.828CysHis: 0.828 ± 0.646
1.656CysIle: 1.656 ± 0.594
0.828CysLys: 0.828 ± 0.707
2.07CysLeu: 2.07 ± 1.313
0.414CysMet: 0.414 ± 0.584
0.414CysAsn: 0.414 ± 0.374
0.414CysPro: 0.414 ± 0.354
0.0CysGln: 0.0 ± 0.0
2.484CysArg: 2.484 ± 0.902
1.242CysSer: 1.242 ± 0.882
2.07CysThr: 2.07 ± 1.223
1.656CysVal: 1.656 ± 1.217
0.414CysTrp: 0.414 ± 0.374
0.414CysTyr: 0.414 ± 0.334
0.0CysXaa: 0.0 ± 0.0
Asp
3.727AspAla: 3.727 ± 1.134
1.242AspCys: 1.242 ± 0.371
2.899AspAsp: 2.899 ± 1.105
5.797AspGlu: 5.797 ± 1.154
1.242AspPhe: 1.242 ± 0.688
6.211AspGly: 6.211 ± 2.054
1.242AspHis: 1.242 ± 0.371
3.727AspIle: 3.727 ± 1.609
2.07AspLys: 2.07 ± 0.692
5.797AspLeu: 5.797 ± 2.561
0.828AspMet: 0.828 ± 0.433
1.242AspAsn: 1.242 ± 0.732
4.555AspPro: 4.555 ± 1.889
1.656AspGln: 1.656 ± 0.681
2.07AspArg: 2.07 ± 0.819
6.625AspSer: 6.625 ± 1.988
4.969AspThr: 4.969 ± 1.329
3.313AspVal: 3.313 ± 1.508
1.242AspTrp: 1.242 ± 0.638
1.242AspTyr: 1.242 ± 0.431
0.0AspXaa: 0.0 ± 0.0
Glu
4.141GluAla: 4.141 ± 1.293
0.828GluCys: 0.828 ± 0.631
4.969GluAsp: 4.969 ± 2.726
7.039GluGlu: 7.039 ± 1.916
3.313GluPhe: 3.313 ± 1.155
7.039GluGly: 7.039 ± 2.243
1.242GluHis: 1.242 ± 0.413
2.899GluIle: 2.899 ± 1.008
1.656GluLys: 1.656 ± 1.272
4.969GluLeu: 4.969 ± 0.982
1.242GluMet: 1.242 ± 0.699
4.969GluAsn: 4.969 ± 1.918
4.969GluPro: 4.969 ± 1.021
2.484GluGln: 2.484 ± 0.839
4.141GluArg: 4.141 ± 1.439
4.141GluSer: 4.141 ± 0.464
4.969GluThr: 4.969 ± 1.317
3.727GluVal: 3.727 ± 1.349
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.484PheAla: 2.484 ± 1.092
1.242PheCys: 1.242 ± 0.823
3.313PheAsp: 3.313 ± 0.729
4.555PheGlu: 4.555 ± 1.613
2.07PhePhe: 2.07 ± 0.927
5.383PheGly: 5.383 ± 0.909
0.0PheHis: 0.0 ± 0.0
1.242PheIle: 1.242 ± 0.371
2.899PheLys: 2.899 ± 1.567
3.727PheLeu: 3.727 ± 1.271
0.0PheMet: 0.0 ± 0.0
2.484PheAsn: 2.484 ± 1.124
2.07PhePro: 2.07 ± 0.808
1.242PheGln: 1.242 ± 0.639
2.899PheArg: 2.899 ± 0.78
2.484PheSer: 2.484 ± 0.727
1.242PheThr: 1.242 ± 0.371
3.727PheVal: 3.727 ± 1.917
1.242PheTrp: 1.242 ± 0.717
1.242PheTyr: 1.242 ± 0.431
0.0PheXaa: 0.0 ± 0.0
Gly
5.383GlyAla: 5.383 ± 1.663
0.828GlyCys: 0.828 ± 0.647
6.211GlyAsp: 6.211 ± 0.955
5.797GlyGlu: 5.797 ± 1.988
2.899GlyPhe: 2.899 ± 0.793
9.524GlyGly: 9.524 ± 3.514
1.242GlyHis: 1.242 ± 0.732
2.899GlyIle: 2.899 ± 0.479
3.727GlyLys: 3.727 ± 1.663
5.383GlyLeu: 5.383 ± 1.738
0.414GlyMet: 0.414 ± 0.374
3.313GlyAsn: 3.313 ± 0.638
6.211GlyPro: 6.211 ± 2.433
2.07GlyGln: 2.07 ± 1.009
6.211GlyArg: 6.211 ± 2.45
7.867GlySer: 7.867 ± 1.479
7.453GlyThr: 7.453 ± 1.567
7.039GlyVal: 7.039 ± 1.106
0.828GlyTrp: 0.828 ± 0.402
0.828GlyTyr: 0.828 ± 0.413
0.0GlyXaa: 0.0 ± 0.0
His
2.07HisAla: 2.07 ± 1.13
1.656HisCys: 1.656 ± 0.571
0.828HisAsp: 0.828 ± 0.402
0.414HisGlu: 0.414 ± 0.354
0.414HisPhe: 0.414 ± 0.334
0.414HisGly: 0.414 ± 0.334
0.414HisHis: 0.414 ± 0.374
2.07HisIle: 2.07 ± 0.486
1.656HisLys: 1.656 ± 0.87
0.828HisLeu: 0.828 ± 0.402
0.828HisMet: 0.828 ± 0.433
0.0HisAsn: 0.0 ± 0.0
2.899HisPro: 2.899 ± 0.875
1.242HisGln: 1.242 ± 0.371
1.656HisArg: 1.656 ± 1.2
0.414HisSer: 0.414 ± 0.394
0.414HisThr: 0.414 ± 0.587
0.414HisVal: 0.414 ± 0.374
0.414HisTrp: 0.414 ± 0.354
0.828HisTyr: 0.828 ± 0.414
0.0HisXaa: 0.0 ± 0.0
Ile
1.242IleAla: 1.242 ± 0.697
0.0IleCys: 0.0 ± 0.0
1.656IleAsp: 1.656 ± 0.831
3.727IleGlu: 3.727 ± 1.047
1.242IlePhe: 1.242 ± 0.717
3.727IleGly: 3.727 ± 1.394
1.242IleHis: 1.242 ± 0.688
2.07IleIle: 2.07 ± 1.193
0.828IleLys: 0.828 ± 0.413
5.383IleLeu: 5.383 ± 1.134
0.414IleMet: 0.414 ± 0.334
1.656IleAsn: 1.656 ± 0.217
1.656IlePro: 1.656 ± 0.611
2.07IleGln: 2.07 ± 0.739
1.242IleArg: 1.242 ± 0.681
2.899IleSer: 2.899 ± 1.031
2.07IleThr: 2.07 ± 0.658
1.242IleVal: 1.242 ± 0.673
0.0IleTrp: 0.0 ± 0.0
2.484IleTyr: 2.484 ± 0.565
0.0IleXaa: 0.0 ± 0.0
Lys
3.727LysAla: 3.727 ± 0.646
2.899LysCys: 2.899 ± 0.899
1.656LysAsp: 1.656 ± 0.618
0.828LysGlu: 0.828 ± 0.461
3.313LysPhe: 3.313 ± 1.225
4.555LysGly: 4.555 ± 0.728
2.07LysHis: 2.07 ± 0.78
0.828LysIle: 0.828 ± 0.613
4.141LysLys: 4.141 ± 0.766
2.07LysLeu: 2.07 ± 0.443
0.828LysMet: 0.828 ± 0.653
2.07LysAsn: 2.07 ± 0.756
2.484LysPro: 2.484 ± 1.365
1.656LysGln: 1.656 ± 0.99
3.727LysArg: 3.727 ± 0.997
4.141LysSer: 4.141 ± 0.983
2.899LysThr: 2.899 ± 0.568
4.141LysVal: 4.141 ± 1.322
0.414LysTrp: 0.414 ± 0.374
2.07LysTyr: 2.07 ± 0.78
0.0LysXaa: 0.0 ± 0.0
Leu
2.899LeuAla: 2.899 ± 1.231
2.07LeuCys: 2.07 ± 0.739
4.969LeuAsp: 4.969 ± 1.256
5.797LeuGlu: 5.797 ± 0.928
3.727LeuPhe: 3.727 ± 1.182
9.11LeuGly: 9.11 ± 2.262
1.242LeuHis: 1.242 ± 0.413
2.484LeuIle: 2.484 ± 1.117
4.555LeuLys: 4.555 ± 1.558
7.867LeuLeu: 7.867 ± 2.275
1.656LeuMet: 1.656 ± 0.691
2.484LeuAsn: 2.484 ± 0.965
3.727LeuPro: 3.727 ± 1.038
3.727LeuGln: 3.727 ± 0.775
4.141LeuArg: 4.141 ± 0.707
10.766LeuSer: 10.766 ± 1.521
4.969LeuThr: 4.969 ± 1.447
4.969LeuVal: 4.969 ± 1.886
1.242LeuTrp: 1.242 ± 0.732
3.727LeuTyr: 3.727 ± 0.646
0.0LeuXaa: 0.0 ± 0.0
Met
2.899MetAla: 2.899 ± 0.733
0.414MetCys: 0.414 ± 0.354
1.656MetAsp: 1.656 ± 0.679
0.828MetGlu: 0.828 ± 0.613
0.414MetPhe: 0.414 ± 0.354
0.414MetGly: 0.414 ± 0.374
0.0MetHis: 0.0 ± 0.0
1.242MetIle: 1.242 ± 0.644
0.0MetLys: 0.0 ± 0.0
0.414MetLeu: 0.414 ± 0.334
1.242MetMet: 1.242 ± 0.701
1.242MetAsn: 1.242 ± 0.732
0.414MetPro: 0.414 ± 0.374
0.0MetGln: 0.0 ± 0.0
1.656MetArg: 1.656 ± 0.831
1.656MetSer: 1.656 ± 0.53
2.07MetThr: 2.07 ± 1.048
0.414MetVal: 0.414 ± 0.334
0.0MetTrp: 0.0 ± 0.0
0.828MetTyr: 0.828 ± 0.631
0.0MetXaa: 0.0 ± 0.0
Asn
1.656AsnAla: 1.656 ± 0.789
0.414AsnCys: 0.414 ± 0.374
1.242AsnAsp: 1.242 ± 0.638
2.07AsnGlu: 2.07 ± 0.739
1.656AsnPhe: 1.656 ± 0.62
5.383AsnGly: 5.383 ± 1.195
0.0AsnHis: 0.0 ± 0.0
2.484AsnIle: 2.484 ± 1.012
2.899AsnLys: 2.899 ± 1.034
0.828AsnLeu: 0.828 ± 0.433
0.828AsnMet: 0.828 ± 0.668
2.484AsnAsn: 2.484 ± 1.387
2.899AsnPro: 2.899 ± 0.781
0.414AsnGln: 0.414 ± 0.354
2.07AsnArg: 2.07 ± 0.74
2.07AsnSer: 2.07 ± 0.859
2.484AsnThr: 2.484 ± 1.151
2.07AsnVal: 2.07 ± 0.725
0.0AsnTrp: 0.0 ± 0.0
1.656AsnTyr: 1.656 ± 0.53
0.0AsnXaa: 0.0 ± 0.0
Pro
4.555ProAla: 4.555 ± 1.126
0.414ProCys: 0.414 ± 0.354
5.383ProAsp: 5.383 ± 1.46
5.383ProGlu: 5.383 ± 1.76
1.656ProPhe: 1.656 ± 0.802
3.727ProGly: 3.727 ± 2.111
0.414ProHis: 0.414 ± 0.374
1.656ProIle: 1.656 ± 0.643
5.383ProLys: 5.383 ± 0.719
6.211ProLeu: 6.211 ± 1.725
1.242ProMet: 1.242 ± 0.586
0.828ProAsn: 0.828 ± 0.433
7.867ProPro: 7.867 ± 1.995
3.313ProGln: 3.313 ± 0.776
4.969ProArg: 4.969 ± 2.31
3.313ProSer: 3.313 ± 0.712
4.555ProThr: 4.555 ± 1.128
4.141ProVal: 4.141 ± 1.155
0.828ProTrp: 0.828 ± 0.747
1.656ProTyr: 1.656 ± 0.923
0.0ProXaa: 0.0 ± 0.0
Gln
1.656GlnAla: 1.656 ± 0.618
1.242GlnCys: 1.242 ± 0.83
0.414GlnAsp: 0.414 ± 0.334
4.141GlnGlu: 4.141 ± 1.146
1.242GlnPhe: 1.242 ± 0.363
2.484GlnGly: 2.484 ± 0.496
0.414GlnHis: 0.414 ± 0.334
0.828GlnIle: 0.828 ± 0.413
0.414GlnLys: 0.414 ± 0.334
4.141GlnLeu: 4.141 ± 1.23
0.414GlnMet: 0.414 ± 0.374
0.828GlnAsn: 0.828 ± 0.413
1.656GlnPro: 1.656 ± 0.826
1.656GlnGln: 1.656 ± 1.335
2.07GlnArg: 2.07 ± 1.468
2.484GlnSer: 2.484 ± 1.251
2.899GlnThr: 2.899 ± 1.482
2.484GlnVal: 2.484 ± 0.849
1.656GlnTrp: 1.656 ± 0.805
2.07GlnTyr: 2.07 ± 0.927
0.0GlnXaa: 0.0 ± 0.0
Arg
2.484ArgAla: 2.484 ± 1.281
2.07ArgCys: 2.07 ± 0.918
3.313ArgAsp: 3.313 ± 1.409
4.969ArgGlu: 4.969 ± 1.344
2.07ArgPhe: 2.07 ± 0.918
3.727ArgGly: 3.727 ± 1.175
3.313ArgHis: 3.313 ± 1.038
2.07ArgIle: 2.07 ± 1.006
3.313ArgLys: 3.313 ± 0.798
6.211ArgLeu: 6.211 ± 0.709
2.484ArgMet: 2.484 ± 1.055
1.656ArgAsn: 1.656 ± 0.838
3.727ArgPro: 3.727 ± 1.802
0.828ArgGln: 0.828 ± 0.668
4.969ArgArg: 4.969 ± 1.974
7.453ArgSer: 7.453 ± 1.508
2.899ArgThr: 2.899 ± 0.601
4.555ArgVal: 4.555 ± 2.004
0.0ArgTrp: 0.0 ± 0.0
0.828ArgTyr: 0.828 ± 0.414
0.0ArgXaa: 0.0 ± 0.0
Ser
2.07SerAla: 2.07 ± 0.945
0.828SerCys: 0.828 ± 0.871
6.211SerAsp: 6.211 ± 0.591
5.383SerGlu: 5.383 ± 1.547
3.313SerPhe: 3.313 ± 1.321
7.867SerGly: 7.867 ± 2.047
2.484SerHis: 2.484 ± 0.838
1.656SerIle: 1.656 ± 0.662
5.383SerLys: 5.383 ± 2.032
6.211SerLeu: 6.211 ± 1.774
2.899SerMet: 2.899 ± 0.888
2.07SerAsn: 2.07 ± 1.669
5.383SerPro: 5.383 ± 1.626
2.07SerGln: 2.07 ± 1.023
5.383SerArg: 5.383 ± 2.463
7.867SerSer: 7.867 ± 2.076
6.625SerThr: 6.625 ± 1.931
4.969SerVal: 4.969 ± 0.505
0.414SerTrp: 0.414 ± 0.334
2.899SerTyr: 2.899 ± 0.544
0.0SerXaa: 0.0 ± 0.0
Thr
2.07ThrAla: 2.07 ± 0.808
2.484ThrCys: 2.484 ± 1.049
4.141ThrAsp: 4.141 ± 1.718
3.313ThrGlu: 3.313 ± 0.434
5.797ThrPhe: 5.797 ± 1.987
4.141ThrGly: 4.141 ± 0.836
1.242ThrHis: 1.242 ± 0.639
2.484ThrIle: 2.484 ± 0.804
2.07ThrLys: 2.07 ± 0.461
6.625ThrLeu: 6.625 ± 1.541
0.0ThrMet: 0.0 ± 0.0
1.656ThrAsn: 1.656 ± 0.802
7.039ThrPro: 7.039 ± 2.725
2.484ThrGln: 2.484 ± 0.853
3.727ThrArg: 3.727 ± 0.653
4.555ThrSer: 4.555 ± 1.335
2.899ThrThr: 2.899 ± 0.992
4.555ThrVal: 4.555 ± 1.409
0.414ThrTrp: 0.414 ± 0.584
0.828ThrTyr: 0.828 ± 0.707
0.0ThrXaa: 0.0 ± 0.0
Val
2.899ValAla: 2.899 ± 0.588
0.828ValCys: 0.828 ± 0.646
4.969ValAsp: 4.969 ± 1.253
2.899ValGlu: 2.899 ± 0.78
2.07ValPhe: 2.07 ± 0.74
5.383ValGly: 5.383 ± 1.218
1.242ValHis: 1.242 ± 1.188
1.656ValIle: 1.656 ± 0.62
1.656ValLys: 1.656 ± 0.618
6.211ValLeu: 6.211 ± 1.364
0.414ValMet: 0.414 ± 0.354
3.313ValAsn: 3.313 ± 0.645
4.555ValPro: 4.555 ± 1.345
4.141ValGln: 4.141 ± 0.8
3.727ValArg: 3.727 ± 1.896
6.211ValSer: 6.211 ± 1.48
2.07ValThr: 2.07 ± 0.738
4.555ValVal: 4.555 ± 1.653
0.828ValTrp: 0.828 ± 0.636
2.07ValTyr: 2.07 ± 0.738
0.0ValXaa: 0.0 ± 0.0
Trp
0.414TrpAla: 0.414 ± 0.334
0.828TrpCys: 0.828 ± 0.871
0.828TrpAsp: 0.828 ± 0.636
0.414TrpGlu: 0.414 ± 0.374
0.414TrpPhe: 0.414 ± 0.374
0.828TrpGly: 0.828 ± 0.747
0.0TrpHis: 0.0 ± 0.0
0.414TrpIle: 0.414 ± 0.334
1.656TrpLys: 1.656 ± 0.681
1.656TrpLeu: 1.656 ± 0.99
0.0TrpMet: 0.0 ± 0.0
1.242TrpAsn: 1.242 ± 1.061
0.414TrpPro: 0.414 ± 0.584
0.0TrpGln: 0.0 ± 0.0
0.414TrpArg: 0.414 ± 0.374
0.828TrpSer: 0.828 ± 0.747
0.828TrpThr: 0.828 ± 0.402
0.828TrpVal: 0.828 ± 0.433
0.0TrpTrp: 0.0 ± 0.0
0.414TrpTyr: 0.414 ± 0.334
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.07TyrAla: 2.07 ± 1.01
1.242TyrCys: 1.242 ± 0.642
1.656TyrAsp: 1.656 ± 0.585
1.242TyrGlu: 1.242 ± 0.413
2.07TyrPhe: 2.07 ± 0.985
0.828TyrGly: 0.828 ± 0.461
0.828TyrHis: 0.828 ± 0.461
0.828TyrIle: 0.828 ± 0.414
2.484TyrLys: 2.484 ± 1.201
3.727TyrLeu: 3.727 ± 1.951
0.828TyrMet: 0.828 ± 0.613
0.828TyrAsn: 0.828 ± 0.413
0.414TyrPro: 0.414 ± 0.354
0.0TyrGln: 0.0 ± 0.0
2.484TyrArg: 2.484 ± 0.93
1.242TyrSer: 1.242 ± 0.662
0.828TyrThr: 0.828 ± 0.402
0.828TyrVal: 0.828 ± 0.413
1.656TyrTrp: 1.656 ± 0.838
2.484TyrTyr: 2.484 ± 1.056
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2416 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski