Amino acid dipepetide frequency for Microbacterium caowuchunii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.239AlaAla: 21.239 ± 0.222	0.684AlaCys: 0.684 ± 0.03	8.718AlaAsp: 8.718 ± 0.114	8.644AlaGlu: 8.644 ± 0.113	3.929AlaPhe: 3.929 ± 0.071	12.785AlaGly: 12.785 ± 0.12	2.507AlaHis: 2.507 ± 0.05	5.686AlaIle: 5.686 ± 0.083	2.366AlaLys: 2.366 ± 0.064	14.351AlaLeu: 14.351 ± 0.139	2.676AlaMet: 2.676 ± 0.055	2.08AlaAsn: 2.08 ± 0.054	6.808AlaPro: 6.808 ± 0.105	3.848AlaGln: 3.848 ± 0.061	10.066AlaArg: 10.066 ± 0.124	6.856AlaSer: 6.856 ± 0.089	7.381AlaThr: 7.381 ± 0.09	12.028AlaVal: 12.028 ± 0.12	1.943AlaTrp: 1.943 ± 0.046	2.465AlaTyr: 2.465 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.724CysAla: 0.724 ± 0.031	0.041CysCys: 0.041 ± 0.007	0.311CysAsp: 0.311 ± 0.019	0.256CysGlu: 0.256 ± 0.018	0.168CysPhe: 0.168 ± 0.014	0.564CysGly: 0.564 ± 0.027	0.125CysHis: 0.125 ± 0.013	0.198CysIle: 0.198 ± 0.014	0.044CysLys: 0.044 ± 0.008	0.438CysLeu: 0.438 ± 0.022	0.083CysMet: 0.083 ± 0.009	0.103CysAsn: 0.103 ± 0.011	0.289CysPro: 0.289 ± 0.022	0.114CysGln: 0.114 ± 0.011	0.389CysArg: 0.389 ± 0.021	0.311CysSer: 0.311 ± 0.019	0.346CysThr: 0.346 ± 0.022	0.438CysVal: 0.438 ± 0.019	0.071CysTrp: 0.071 ± 0.009	0.097CysTyr: 0.097 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	9.542AspAla: 9.542 ± 0.104	0.241AspCys: 0.241 ± 0.016	4.09AspAsp: 4.09 ± 0.088	4.282AspGlu: 4.282 ± 0.072	1.615AspPhe: 1.615 ± 0.044	6.052AspGly: 6.052 ± 0.099	1.161AspHis: 1.161 ± 0.037	2.45AspIle: 2.45 ± 0.054	0.878AspLys: 0.878 ± 0.036	6.258AspLeu: 6.258 ± 0.081	0.897AspMet: 0.897 ± 0.034	0.879AspAsn: 0.879 ± 0.034	4.508AspPro: 4.508 ± 0.063	1.437AspGln: 1.437 ± 0.042	4.769AspArg: 4.769 ± 0.073	2.459AspSer: 2.459 ± 0.05	2.949AspThr: 2.949 ± 0.051	5.731AspVal: 5.731 ± 0.083	0.919AspTrp: 0.919 ± 0.031	1.219AspTyr: 1.219 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	6.927GluAla: 6.927 ± 0.097	0.269GluCys: 0.269 ± 0.018	3.152GluAsp: 3.152 ± 0.063	3.218GluGlu: 3.218 ± 0.067	1.699GluPhe: 1.699 ± 0.04	4.193GluGly: 4.193 ± 0.08	1.349GluHis: 1.349 ± 0.034	2.837GluIle: 2.837 ± 0.057	1.309GluLys: 1.309 ± 0.046	6.33GluLeu: 6.33 ± 0.078	0.931GluMet: 0.931 ± 0.034	1.269GluAsn: 1.269 ± 0.042	3.052GluPro: 3.052 ± 0.064	2.138GluGln: 2.138 ± 0.046	5.499GluArg: 5.499 ± 0.082	2.871GluSer: 2.871 ± 0.049	3.144GluThr: 3.144 ± 0.065	4.634GluVal: 4.634 ± 0.077	0.9GluTrp: 0.9 ± 0.033	1.187GluTyr: 1.187 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	4.297PheAla: 4.297 ± 0.068	0.162PheCys: 0.162 ± 0.013	2.285PheAsp: 2.285 ± 0.055	1.66PheGlu: 1.66 ± 0.045	1.072PhePhe: 1.072 ± 0.038	3.3PheGly: 3.3 ± 0.063	0.565PheHis: 0.565 ± 0.024	1.081PheIle: 1.081 ± 0.033	0.361PheLys: 0.361 ± 0.022	2.896PheLeu: 2.896 ± 0.059	0.409PheMet: 0.409 ± 0.021	0.583PheAsn: 0.583 ± 0.025	1.504PhePro: 1.504 ± 0.043	0.774PheGln: 0.774 ± 0.026	1.894PheArg: 1.894 ± 0.043	1.689PheSer: 1.689 ± 0.047	2.126PheThr: 2.126 ± 0.05	2.831PheVal: 2.831 ± 0.062	0.472PheTrp: 0.472 ± 0.024	0.644PheTyr: 0.644 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	11.147GlyAla: 11.147 ± 0.12	0.629GlyCys: 0.629 ± 0.029	5.15GlyAsp: 5.15 ± 0.079	5.115GlyGlu: 5.115 ± 0.088	3.255GlyPhe: 3.255 ± 0.06	7.947GlyGly: 7.947 ± 0.126	1.843GlyHis: 1.843 ± 0.042	4.846GlyIle: 4.846 ± 0.073	1.962GlyLys: 1.962 ± 0.048	8.647GlyLeu: 8.647 ± 0.098	2.108GlyMet: 2.108 ± 0.049	1.632GlyAsn: 1.632 ± 0.052	4.048GlyPro: 4.048 ± 0.064	2.311GlyGln: 2.311 ± 0.053	6.877GlyArg: 6.877 ± 0.087	5.163GlySer: 5.163 ± 0.076	5.792GlyThr: 5.792 ± 0.09	8.025GlyVal: 8.025 ± 0.101	1.679GlyTrp: 1.679 ± 0.041	2.239GlyTyr: 2.239 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.374HisAla: 2.374 ± 0.049	0.131HisCys: 0.131 ± 0.011	1.264HisAsp: 1.264 ± 0.036	1.077HisGlu: 1.077 ± 0.033	0.524HisPhe: 0.524 ± 0.023	1.984HisGly: 1.984 ± 0.05	0.544HisHis: 0.544 ± 0.028	0.759HisIle: 0.759 ± 0.027	0.239HisLys: 0.239 ± 0.013	2.047HisLeu: 2.047 ± 0.047	0.314HisMet: 0.314 ± 0.021	0.289HisAsn: 0.289 ± 0.017	1.607HisPro: 1.607 ± 0.039	0.457HisGln: 0.457 ± 0.021	1.639HisArg: 1.639 ± 0.043	0.943HisSer: 0.943 ± 0.031	1.008HisThr: 1.008 ± 0.031	1.714HisVal: 1.714 ± 0.041	0.261HisTrp: 0.261 ± 0.019	0.395HisTyr: 0.395 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.923IleAla: 6.923 ± 0.098	0.243IleCys: 0.243 ± 0.018	3.296IleAsp: 3.296 ± 0.053	2.8IleGlu: 2.8 ± 0.051	1.071IlePhe: 1.071 ± 0.039	4.616IleGly: 4.616 ± 0.08	0.71IleHis: 0.71 ± 0.025	1.712IleIle: 1.712 ± 0.047	0.647IleLys: 0.647 ± 0.032	3.859IleLeu: 3.859 ± 0.059	0.611IleMet: 0.611 ± 0.023	0.789IleAsn: 0.789 ± 0.031	2.548IlePro: 2.548 ± 0.048	0.946IleGln: 0.946 ± 0.031	2.926IleArg: 2.926 ± 0.052	2.289IleSer: 2.289 ± 0.049	2.711IleThr: 2.711 ± 0.056	4.763IleVal: 4.763 ± 0.066	0.483IleTrp: 0.483 ± 0.025	0.718IleTyr: 0.718 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	2.088LysAla: 2.088 ± 0.05	0.06LysCys: 0.06 ± 0.008	0.986LysAsp: 0.986 ± 0.037	0.871LysGlu: 0.871 ± 0.035	0.394LysPhe: 0.394 ± 0.02	1.388LysGly: 1.388 ± 0.042	0.358LysHis: 0.358 ± 0.023	0.842LysIle: 0.842 ± 0.032	0.662LysLys: 0.662 ± 0.031	1.615LysLeu: 1.615 ± 0.044	0.326LysMet: 0.326 ± 0.018	0.46LysAsn: 0.46 ± 0.022	1.028LysPro: 1.028 ± 0.036	0.51LysGln: 0.51 ± 0.024	1.39LysArg: 1.39 ± 0.045	1.003LysSer: 1.003 ± 0.037	1.216LysThr: 1.216 ± 0.035	1.486LysVal: 1.486 ± 0.045	0.206LysTrp: 0.206 ± 0.015	0.387LysTyr: 0.387 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.633LeuAla: 14.633 ± 0.143	0.532LeuCys: 0.532 ± 0.025	6.552LeuAsp: 6.552 ± 0.088	5.174LeuGlu: 5.174 ± 0.089	2.903LeuPhe: 2.903 ± 0.074	9.164LeuGly: 9.164 ± 0.123	1.807LeuHis: 1.807 ± 0.047	4.409LeuIle: 4.409 ± 0.079	1.497LeuLys: 1.497 ± 0.043	10.075LeuLeu: 10.075 ± 0.145	1.634LeuMet: 1.634 ± 0.047	1.662LeuAsn: 1.662 ± 0.038	5.594LeuPro: 5.594 ± 0.078	2.541LeuGln: 2.541 ± 0.053	7.782LeuArg: 7.782 ± 0.1	5.902LeuSer: 5.902 ± 0.093	6.325LeuThr: 6.325 ± 0.096	9.437LeuVal: 9.437 ± 0.13	1.335LeuTrp: 1.335 ± 0.039	1.655LeuTyr: 1.655 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.118MetAla: 2.118 ± 0.048	0.113MetCys: 0.113 ± 0.01	0.872MetAsp: 0.872 ± 0.032	0.639MetGlu: 0.639 ± 0.027	0.469MetPhe: 0.469 ± 0.024	1.429MetGly: 1.429 ± 0.043	0.324MetHis: 0.324 ± 0.019	0.781MetIle: 0.781 ± 0.03	0.395MetLys: 0.395 ± 0.02	1.937MetLeu: 1.937 ± 0.046	0.34MetMet: 0.34 ± 0.022	0.439MetAsn: 0.439 ± 0.021	1.161MetPro: 1.161 ± 0.035	0.567MetGln: 0.567 ± 0.022	1.507MetArg: 1.507 ± 0.038	1.418MetSer: 1.418 ± 0.033	1.777MetThr: 1.777 ± 0.044	1.329MetVal: 1.329 ± 0.038	0.224MetTrp: 0.224 ± 0.016	0.276MetTyr: 0.276 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.413AsnAla: 2.413 ± 0.054	0.107AsnCys: 0.107 ± 0.011	1.043AsnAsp: 1.043 ± 0.034	0.928AsnGlu: 0.928 ± 0.034	0.537AsnPhe: 0.537 ± 0.023	1.802AsnGly: 1.802 ± 0.053	0.317AsnHis: 0.317 ± 0.016	0.807AsnIle: 0.807 ± 0.03	0.333AsnLys: 0.333 ± 0.019	1.726AsnLeu: 1.726 ± 0.047	0.309AsnMet: 0.309 ± 0.018	0.39AsnAsn: 0.39 ± 0.021	1.493AsnPro: 1.493 ± 0.046	0.48AsnGln: 0.48 ± 0.021	1.212AsnArg: 1.212 ± 0.039	0.851AsnSer: 0.851 ± 0.032	1.061AsnThr: 1.061 ± 0.039	1.596AsnVal: 1.596 ± 0.043	0.276AsnTrp: 0.276 ± 0.016	0.42AsnTyr: 0.42 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	7.982ProAla: 7.982 ± 0.113	0.19ProCys: 0.19 ± 0.015	4.169ProAsp: 4.169 ± 0.066	4.011ProGlu: 4.011 ± 0.068	1.713ProPhe: 1.713 ± 0.038	5.361ProGly: 5.361 ± 0.089	1.216ProHis: 1.216 ± 0.04	2.049ProIle: 2.049 ± 0.047	0.872ProLys: 0.872 ± 0.034	5.116ProLeu: 5.116 ± 0.084	0.903ProMet: 0.903 ± 0.031	0.922ProAsn: 0.922 ± 0.032	2.469ProPro: 2.469 ± 0.06	1.483ProGln: 1.483 ± 0.04	3.898ProArg: 3.898 ± 0.069	3.054ProSer: 3.054 ± 0.059	3.288ProThr: 3.288 ± 0.067	5.116ProVal: 5.116 ± 0.074	0.92ProTrp: 0.92 ± 0.034	1.038ProTyr: 1.038 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.318GlnAla: 3.318 ± 0.061	0.088GlnCys: 0.088 ± 0.01	1.378GlnAsp: 1.378 ± 0.042	1.344GlnGlu: 1.344 ± 0.04	0.79GlnPhe: 0.79 ± 0.028	2.0GlnGly: 2.0 ± 0.043	0.556GlnHis: 0.556 ± 0.022	1.396GlnIle: 1.396 ± 0.035	0.592GlnLys: 0.592 ± 0.026	2.903GlnLeu: 2.903 ± 0.057	0.489GlnMet: 0.489 ± 0.021	0.626GlnAsn: 0.626 ± 0.027	1.438GlnPro: 1.438 ± 0.04	1.052GlnGln: 1.052 ± 0.036	2.404GlnArg: 2.404 ± 0.052	1.403GlnSer: 1.403 ± 0.04	1.549GlnThr: 1.549 ± 0.037	2.328GlnVal: 2.328 ± 0.053	0.448GlnTrp: 0.448 ± 0.022	0.561GlnTyr: 0.561 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	9.869ArgAla: 9.869 ± 0.126	0.353ArgCys: 0.353 ± 0.023	4.528ArgAsp: 4.528 ± 0.066	4.567ArgGlu: 4.567 ± 0.075	2.5ArgPhe: 2.5 ± 0.058	5.767ArgGly: 5.767 ± 0.086	1.67ArgHis: 1.67 ± 0.046	3.998ArgIle: 3.998 ± 0.066	1.287ArgLys: 1.287 ± 0.043	7.566ArgLeu: 7.566 ± 0.118	1.967ArgMet: 1.967 ± 0.041	1.379ArgAsn: 1.379 ± 0.041	4.055ArgPro: 4.055 ± 0.07	1.977ArgGln: 1.977 ± 0.048	7.285ArgArg: 7.285 ± 0.13	4.302ArgSer: 4.302 ± 0.066	4.767ArgThr: 4.767 ± 0.081	6.51ArgVal: 6.51 ± 0.084	1.184ArgTrp: 1.184 ± 0.041	1.61ArgTyr: 1.61 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	7.386SerAla: 7.386 ± 0.091	0.256SerCys: 0.256 ± 0.015	3.069SerAsp: 3.069 ± 0.062	2.604SerGlu: 2.604 ± 0.053	1.877SerPhe: 1.877 ± 0.044	5.757SerGly: 5.757 ± 0.083	0.996SerHis: 0.996 ± 0.037	2.332SerIle: 2.332 ± 0.053	0.857SerLys: 0.857 ± 0.034	5.256SerLeu: 5.256 ± 0.083	1.087SerMet: 1.087 ± 0.034	0.979SerAsn: 0.979 ± 0.031	3.127SerPro: 3.127 ± 0.063	1.226SerGln: 1.226 ± 0.036	3.86SerArg: 3.86 ± 0.069	3.162SerSer: 3.162 ± 0.061	3.311SerThr: 3.311 ± 0.06	4.718SerVal: 4.718 ± 0.057	0.907SerTrp: 0.907 ± 0.031	1.105SerTyr: 1.105 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	7.984ThrAla: 7.984 ± 0.115	0.29ThrCys: 0.29 ± 0.021	3.683ThrAsp: 3.683 ± 0.075	3.05ThrGlu: 3.05 ± 0.056	1.848ThrPhe: 1.848 ± 0.042	5.955ThrGly: 5.955 ± 0.096	1.171ThrHis: 1.171 ± 0.035	2.816ThrIle: 2.816 ± 0.06	1.0ThrLys: 1.0 ± 0.041	6.033ThrLeu: 6.033 ± 0.096	0.956ThrMet: 0.956 ± 0.034	1.068ThrAsn: 1.068 ± 0.036	4.046ThrPro: 4.046 ± 0.073	1.383ThrGln: 1.383 ± 0.04	4.035ThrArg: 4.035 ± 0.067	3.212ThrSer: 3.212 ± 0.062	3.622ThrThr: 3.622 ± 0.069	6.036ThrVal: 6.036 ± 0.097	0.891ThrTrp: 0.891 ± 0.032	1.246ThrTyr: 1.246 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	11.853ValAla: 11.853 ± 0.129	0.524ValCys: 0.524 ± 0.023	5.632ValAsp: 5.632 ± 0.073	4.835ValGlu: 4.835 ± 0.079	2.983ValPhe: 2.983 ± 0.06	7.223ValGly: 7.223 ± 0.1	1.735ValHis: 1.735 ± 0.04	4.262ValIle: 4.262 ± 0.069	1.406ValLys: 1.406 ± 0.041	9.838ValLeu: 9.838 ± 0.133	1.474ValMet: 1.474 ± 0.045	1.761ValAsn: 1.761 ± 0.043	5.165ValPro: 5.165 ± 0.075	2.327ValGln: 2.327 ± 0.045	6.665ValArg: 6.665 ± 0.083	5.028ValSer: 5.028 ± 0.075	5.87ValThr: 5.87 ± 0.102	9.209ValVal: 9.209 ± 0.128	1.241ValTrp: 1.241 ± 0.047	1.703ValTyr: 1.703 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	1.679TrpAla: 1.679 ± 0.044	0.091TrpCys: 0.091 ± 0.009	0.835TrpAsp: 0.835 ± 0.032	0.72TrpGlu: 0.72 ± 0.03	0.58TrpPhe: 0.58 ± 0.028	1.139TrpGly: 1.139 ± 0.032	0.324TrpHis: 0.324 ± 0.018	0.701TrpIle: 0.701 ± 0.029	0.274TrpLys: 0.274 ± 0.017	1.658TrpLeu: 1.658 ± 0.046	0.349TrpMet: 0.349 ± 0.02	0.384TrpAsn: 0.384 ± 0.019	0.77TrpPro: 0.77 ± 0.033	0.503TrpGln: 0.503 ± 0.022	1.313TrpArg: 1.313 ± 0.038	0.932TrpSer: 0.932 ± 0.032	0.91TrpThr: 0.91 ± 0.035	1.179TrpVal: 1.179 ± 0.03	0.358TrpTrp: 0.358 ± 0.019	0.313TrpTyr: 0.313 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.566TyrAla: 2.566 ± 0.047	0.108TyrCys: 0.108 ± 0.009	1.323TyrAsp: 1.323 ± 0.044	1.114TyrGlu: 1.114 ± 0.03	0.679TyrPhe: 0.679 ± 0.029	1.989TyrGly: 1.989 ± 0.046	0.291TyrHis: 0.291 ± 0.016	0.698TyrIle: 0.698 ± 0.029	0.295TyrLys: 0.295 ± 0.017	2.063TyrLeu: 2.063 ± 0.049	0.249TyrMet: 0.249 ± 0.016	0.408TyrAsn: 0.408 ± 0.021	1.06TyrPro: 1.06 ± 0.033	0.588TyrGln: 0.588 ± 0.025	1.731TyrArg: 1.731 ± 0.047	1.027TyrSer: 1.027 ± 0.034	1.169TyrThr: 1.169 ± 0.037	1.626TyrVal: 1.626 ± 0.041	0.294TyrTrp: 0.294 ± 0.016	0.436TyrTyr: 0.436 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3053 proteins (992905 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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