Amino acid dipepetide frequency for Stenotrophomonas maltophilia (strain K279a)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.719AlaAla: 17.719 ± 0.161	1.226AlaCys: 1.226 ± 0.037	7.096AlaAsp: 7.096 ± 0.097	6.712AlaGlu: 6.712 ± 0.09	3.875AlaPhe: 3.875 ± 0.055	11.251AlaGly: 11.251 ± 0.145	2.435AlaHis: 2.435 ± 0.045	5.032AlaIle: 5.032 ± 0.064	3.288AlaLys: 3.288 ± 0.069	15.418AlaLeu: 15.418 ± 0.142	3.362AlaMet: 3.362 ± 0.058	3.11AlaAsn: 3.11 ± 0.062	6.507AlaPro: 6.507 ± 0.091	5.914AlaGln: 5.914 ± 0.092	9.215AlaArg: 9.215 ± 0.103	7.006AlaSer: 7.006 ± 0.086	6.267AlaThr: 6.267 ± 0.087	8.803AlaVal: 8.803 ± 0.096	2.035AlaTrp: 2.035 ± 0.041	2.475AlaTyr: 2.475 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.958CysAla: 0.958 ± 0.03	0.098CysCys: 0.098 ± 0.009	0.439CysAsp: 0.439 ± 0.018	0.402CysGlu: 0.402 ± 0.018	0.271CysPhe: 0.271 ± 0.014	0.844CysGly: 0.844 ± 0.03	0.244CysHis: 0.244 ± 0.015	0.302CysIle: 0.302 ± 0.016	0.173CysLys: 0.173 ± 0.013	0.819CysLeu: 0.819 ± 0.024	0.165CysMet: 0.165 ± 0.012	0.219CysAsn: 0.219 ± 0.012	0.408CysPro: 0.408 ± 0.018	0.306CysGln: 0.306 ± 0.013	0.644CysArg: 0.644 ± 0.025	0.497CysSer: 0.497 ± 0.021	0.475CysThr: 0.475 ± 0.017	0.632CysVal: 0.632 ± 0.022	0.146CysTrp: 0.146 ± 0.009	0.185CysTyr: 0.185 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	8.106AspAla: 8.106 ± 0.088	0.416AspCys: 0.416 ± 0.015	3.229AspAsp: 3.229 ± 0.049	3.026AspGlu: 3.026 ± 0.058	1.969AspPhe: 1.969 ± 0.043	5.721AspGly: 5.721 ± 0.079	1.25AspHis: 1.25 ± 0.036	2.325AspIle: 2.325 ± 0.054	1.476AspLys: 1.476 ± 0.037	5.492AspLeu: 5.492 ± 0.067	1.027AspMet: 1.027 ± 0.031	1.484AspAsn: 1.484 ± 0.048	3.366AspPro: 3.366 ± 0.045	1.776AspGln: 1.776 ± 0.029	3.833AspArg: 3.833 ± 0.059	2.697AspSer: 2.697 ± 0.049	2.63AspThr: 2.63 ± 0.05	4.178AspVal: 4.178 ± 0.066	1.086AspTrp: 1.086 ± 0.028	1.659AspTyr: 1.659 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.64GluAla: 6.64 ± 0.095	0.331GluCys: 0.331 ± 0.016	2.526GluAsp: 2.526 ± 0.045	2.28GluGlu: 2.28 ± 0.045	1.577GluPhe: 1.577 ± 0.036	3.965GluGly: 3.965 ± 0.055	1.319GluHis: 1.319 ± 0.031	2.218GluIle: 2.218 ± 0.048	1.495GluLys: 1.495 ± 0.041	5.861GluLeu: 5.861 ± 0.069	1.006GluMet: 1.006 ± 0.025	1.156GluAsn: 1.156 ± 0.03	2.372GluPro: 2.372 ± 0.048	2.907GluGln: 2.907 ± 0.051	4.881GluArg: 4.881 ± 0.069	2.329GluSer: 2.329 ± 0.041	2.315GluThr: 2.315 ± 0.037	3.748GluVal: 3.748 ± 0.061	0.666GluTrp: 0.666 ± 0.023	1.062GluTyr: 1.062 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.049PheAla: 4.049 ± 0.065	0.318PheCys: 0.318 ± 0.016	2.522PheAsp: 2.522 ± 0.042	1.81PheGlu: 1.81 ± 0.037	1.166PhePhe: 1.166 ± 0.032	3.3PheGly: 3.3 ± 0.053	0.745PheHis: 0.745 ± 0.023	1.246PheIle: 1.246 ± 0.033	0.904PheLys: 0.904 ± 0.028	2.874PheLeu: 2.874 ± 0.057	0.644PheMet: 0.644 ± 0.023	1.185PheAsn: 1.185 ± 0.029	1.367PhePro: 1.367 ± 0.037	1.081PheGln: 1.081 ± 0.029	1.986PheArg: 1.986 ± 0.033	2.041PheSer: 2.041 ± 0.041	1.738PheThr: 1.738 ± 0.035	2.434PheVal: 2.434 ± 0.042	0.471PheTrp: 0.471 ± 0.021	0.795PheTyr: 0.795 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.042GlyAla: 9.042 ± 0.133	0.822GlyCys: 0.822 ± 0.023	4.594GlyAsp: 4.594 ± 0.068	4.564GlyGlu: 4.564 ± 0.062	3.323GlyPhe: 3.323 ± 0.059	7.409GlyGly: 7.409 ± 0.158	2.084GlyHis: 2.084 ± 0.035	3.865GlyIle: 3.865 ± 0.057	2.984GlyLys: 2.984 ± 0.059	9.036GlyLeu: 9.036 ± 0.097	2.262GlyMet: 2.262 ± 0.044	2.809GlyAsn: 2.809 ± 0.081	3.122GlyPro: 3.122 ± 0.048	3.867GlyGln: 3.867 ± 0.061	6.152GlyArg: 6.152 ± 0.076	5.2GlySer: 5.2 ± 0.107	4.609GlyThr: 4.609 ± 0.1	6.414GlyVal: 6.414 ± 0.076	1.732GlyTrp: 1.732 ± 0.041	2.367GlyTyr: 2.367 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	3.037HisAla: 3.037 ± 0.056	0.25HisCys: 0.25 ± 0.013	1.422HisAsp: 1.422 ± 0.036	1.102HisGlu: 1.102 ± 0.028	0.797HisPhe: 0.797 ± 0.023	2.298HisGly: 2.298 ± 0.049	0.605HisHis: 0.605 ± 0.025	0.735HisIle: 0.735 ± 0.02	0.462HisLys: 0.462 ± 0.019	2.243HisLeu: 2.243 ± 0.041	0.434HisMet: 0.434 ± 0.02	0.508HisAsn: 0.508 ± 0.021	1.427HisPro: 1.427 ± 0.038	0.731HisGln: 0.731 ± 0.022	1.705HisArg: 1.705 ± 0.041	1.089HisSer: 1.089 ± 0.03	0.983HisThr: 0.983 ± 0.026	1.518HisVal: 1.518 ± 0.035	0.494HisTrp: 0.494 ± 0.019	0.614HisTyr: 0.614 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.021IleAla: 6.021 ± 0.071	0.338IleCys: 0.338 ± 0.015	3.199IleAsp: 3.199 ± 0.047	2.785IleGlu: 2.785 ± 0.052	1.002IlePhe: 1.002 ± 0.03	4.324IleGly: 4.324 ± 0.068	0.829IleHis: 0.829 ± 0.024	1.39IleIle: 1.39 ± 0.036	1.126IleLys: 1.126 ± 0.03	2.96IleLeu: 2.96 ± 0.048	0.542IleMet: 0.542 ± 0.019	1.322IleAsn: 1.322 ± 0.038	1.938IlePro: 1.938 ± 0.043	1.154IleGln: 1.154 ± 0.026	2.455IleArg: 2.455 ± 0.043	2.336IleSer: 2.336 ± 0.042	2.231IleThr: 2.231 ± 0.047	2.982IleVal: 2.982 ± 0.053	0.416IleTrp: 0.416 ± 0.017	0.801IleTyr: 0.801 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.45LysAla: 3.45 ± 0.066	0.145LysCys: 0.145 ± 0.011	1.49LysAsp: 1.49 ± 0.035	1.196LysGlu: 1.196 ± 0.034	0.666LysPhe: 0.666 ± 0.026	2.18LysGly: 2.18 ± 0.042	0.573LysHis: 0.573 ± 0.023	1.093LysIle: 1.093 ± 0.035	1.003LysLys: 1.003 ± 0.051	2.867LysLeu: 2.867 ± 0.058	0.617LysMet: 0.617 ± 0.022	0.676LysAsn: 0.676 ± 0.023	1.745LysPro: 1.745 ± 0.042	1.236LysGln: 1.236 ± 0.031	2.125LysArg: 2.125 ± 0.041	1.27LysSer: 1.27 ± 0.032	1.38LysThr: 1.38 ± 0.034	2.276LysVal: 2.276 ± 0.044	0.286LysTrp: 0.286 ± 0.014	0.59LysTyr: 0.59 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	15.006LeuAla: 15.006 ± 0.143	0.992LeuCys: 0.992 ± 0.029	6.558LeuAsp: 6.558 ± 0.084	4.988LeuGlu: 4.988 ± 0.066	3.466LeuPhe: 3.466 ± 0.059	8.854LeuGly: 8.854 ± 0.106	2.584LeuHis: 2.584 ± 0.047	3.826LeuIle: 3.826 ± 0.059	3.017LeuLys: 3.017 ± 0.044	12.751LeuLeu: 12.751 ± 0.159	2.17LeuMet: 2.17 ± 0.038	2.44LeuAsn: 2.44 ± 0.046	6.881LeuPro: 6.881 ± 0.08	5.622LeuGln: 5.622 ± 0.079	8.756LeuArg: 8.756 ± 0.095	6.222LeuSer: 6.222 ± 0.076	4.811LeuThr: 4.811 ± 0.068	7.745LeuVal: 7.745 ± 0.092	1.458LeuTrp: 1.458 ± 0.04	2.193LeuTyr: 2.193 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	2.822MetAla: 2.822 ± 0.052	0.143MetCys: 0.143 ± 0.009	1.122MetAsp: 1.122 ± 0.029	0.922MetGlu: 0.922 ± 0.029	0.606MetPhe: 0.606 ± 0.021	1.59MetGly: 1.59 ± 0.033	0.466MetHis: 0.466 ± 0.019	0.884MetIle: 0.884 ± 0.027	0.761MetLys: 0.761 ± 0.023	2.425MetLeu: 2.425 ± 0.051	0.504MetMet: 0.504 ± 0.022	0.702MetAsn: 0.702 ± 0.023	1.441MetPro: 1.441 ± 0.033	1.06MetGln: 1.06 ± 0.034	1.687MetArg: 1.687 ± 0.038	1.547MetSer: 1.547 ± 0.035	1.302MetThr: 1.302 ± 0.032	1.464MetVal: 1.464 ± 0.036	0.23MetTrp: 0.23 ± 0.013	0.353MetTyr: 0.353 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.465AsnAla: 3.465 ± 0.067	0.186AsnCys: 0.186 ± 0.01	1.495AsnAsp: 1.495 ± 0.034	1.266AsnGlu: 1.266 ± 0.032	0.836AsnPhe: 0.836 ± 0.029	2.682AsnGly: 2.682 ± 0.078	0.55AsnHis: 0.55 ± 0.021	1.058AsnIle: 1.058 ± 0.031	0.652AsnLys: 0.652 ± 0.027	2.621AsnLeu: 2.621 ± 0.049	0.415AsnMet: 0.415 ± 0.017	0.777AsnAsn: 0.777 ± 0.036	1.725AsnPro: 1.725 ± 0.04	0.946AsnGln: 0.946 ± 0.027	1.856AsnArg: 1.856 ± 0.042	1.313AsnSer: 1.313 ± 0.042	1.456AsnThr: 1.456 ± 0.05	1.973AsnVal: 1.973 ± 0.046	0.422AsnTrp: 0.422 ± 0.018	0.691AsnTyr: 0.691 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	7.621ProAla: 7.621 ± 0.099	0.311ProCys: 0.311 ± 0.016	3.151ProAsp: 3.151 ± 0.05	3.084ProGlu: 3.084 ± 0.048	1.652ProPhe: 1.652 ± 0.034	4.753ProGly: 4.753 ± 0.065	1.09ProHis: 1.09 ± 0.03	1.839ProIle: 1.839 ± 0.045	1.386ProLys: 1.386 ± 0.035	5.706ProLeu: 5.706 ± 0.075	1.406ProMet: 1.406 ± 0.033	1.206ProAsn: 1.206 ± 0.033	2.81ProPro: 2.81 ± 0.059	2.308ProGln: 2.308 ± 0.047	3.387ProArg: 3.387 ± 0.051	2.866ProSer: 2.866 ± 0.047	2.471ProThr: 2.471 ± 0.047	4.246ProVal: 4.246 ± 0.06	0.911ProTrp: 0.911 ± 0.023	1.144ProTyr: 1.144 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	6.367GlnAla: 6.367 ± 0.09	0.316GlnCys: 0.316 ± 0.016	1.854GlnAsp: 1.854 ± 0.034	1.609GlnGlu: 1.609 ± 0.038	1.253GlnPhe: 1.253 ± 0.036	3.398GlnGly: 3.398 ± 0.062	1.06GlnHis: 1.06 ± 0.027	1.735GlnIle: 1.735 ± 0.034	1.006GlnLys: 1.006 ± 0.027	5.171GlnLeu: 5.171 ± 0.072	0.92GlnMet: 0.92 ± 0.022	0.838GlnAsn: 0.838 ± 0.025	2.519GlnPro: 2.519 ± 0.048	2.75GlnGln: 2.75 ± 0.057	4.279GlnArg: 4.279 ± 0.072	1.941GlnSer: 1.941 ± 0.042	1.759GlnThr: 1.759 ± 0.036	3.566GlnVal: 3.566 ± 0.055	0.844GlnTrp: 0.844 ± 0.023	0.889GlnTyr: 0.889 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	8.009ArgAla: 8.009 ± 0.084	0.589ArgCys: 0.589 ± 0.023	4.256ArgAsp: 4.256 ± 0.058	4.451ArgGlu: 4.451 ± 0.064	2.849ArgPhe: 2.849 ± 0.042	5.353ArgGly: 5.353 ± 0.063	1.923ArgHis: 1.923 ± 0.037	3.666ArgIle: 3.666 ± 0.053	1.852ArgLys: 1.852 ± 0.037	8.461ArgLeu: 8.461 ± 0.103	2.014ArgMet: 2.014 ± 0.039	2.063ArgAsn: 2.063 ± 0.039	3.439ArgPro: 3.439 ± 0.051	3.544ArgGln: 3.544 ± 0.055	5.939ArgArg: 5.939 ± 0.083	4.046ArgSer: 4.046 ± 0.055	3.371ArgThr: 3.371 ± 0.046	5.195ArgVal: 5.195 ± 0.067	1.574ArgTrp: 1.574 ± 0.036	2.155ArgTyr: 2.155 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.729SerAla: 6.729 ± 0.087	0.423SerCys: 0.423 ± 0.02	2.755SerAsp: 2.755 ± 0.044	2.534SerGlu: 2.534 ± 0.041	1.872SerPhe: 1.872 ± 0.036	5.211SerGly: 5.211 ± 0.086	1.205SerHis: 1.205 ± 0.031	2.257SerIle: 2.257 ± 0.043	1.452SerLys: 1.452 ± 0.039	5.851SerLeu: 5.851 ± 0.07	1.19SerMet: 1.19 ± 0.03	1.633SerAsn: 1.633 ± 0.038	2.923SerPro: 2.923 ± 0.04	2.064SerGln: 2.064 ± 0.045	3.876SerArg: 3.876 ± 0.051	3.193SerSer: 3.193 ± 0.06	3.005SerThr: 3.005 ± 0.053	3.928SerVal: 3.928 ± 0.067	0.87SerTrp: 0.87 ± 0.023	1.367SerTyr: 1.367 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	6.126ThrAla: 6.126 ± 0.088	0.368ThrCys: 0.368 ± 0.018	2.553ThrAsp: 2.553 ± 0.044	2.137ThrGlu: 2.137 ± 0.045	1.653ThrPhe: 1.653 ± 0.039	4.548ThrGly: 4.548 ± 0.087	1.039ThrHis: 1.039 ± 0.025	1.891ThrIle: 1.891 ± 0.044	0.931ThrLys: 0.931 ± 0.028	6.338ThrLeu: 6.338 ± 0.098	0.87ThrMet: 0.87 ± 0.026	1.094ThrAsn: 1.094 ± 0.034	3.468ThrPro: 3.468 ± 0.052	1.716ThrGln: 1.716 ± 0.041	3.398ThrArg: 3.398 ± 0.047	2.486ThrSer: 2.486 ± 0.044	2.755ThrThr: 2.755 ± 0.06	4.043ThrVal: 4.043 ± 0.064	0.727ThrTrp: 0.727 ± 0.021	1.095ThrTyr: 1.095 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	9.489ValAla: 9.489 ± 0.101	0.608ValCys: 0.608 ± 0.022	4.392ValAsp: 4.392 ± 0.063	4.096ValGlu: 4.096 ± 0.063	2.438ValPhe: 2.438 ± 0.046	5.595ValGly: 5.595 ± 0.089	1.605ValHis: 1.605 ± 0.038	3.308ValIle: 3.308 ± 0.059	1.853ValLys: 1.853 ± 0.04	8.58ValLeu: 8.58 ± 0.101	1.608ValMet: 1.608 ± 0.041	1.963ValAsn: 1.963 ± 0.042	3.921ValPro: 3.921 ± 0.061	3.081ValGln: 3.081 ± 0.046	5.225ValArg: 5.225 ± 0.068	4.049ValSer: 4.049 ± 0.056	3.628ValThr: 3.628 ± 0.056	5.88ValVal: 5.88 ± 0.075	0.921ValTrp: 0.921 ± 0.024	1.467ValTyr: 1.467 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.374TrpAla: 1.374 ± 0.037	0.154TrpCys: 0.154 ± 0.01	0.717TrpAsp: 0.717 ± 0.025	0.595TrpGlu: 0.595 ± 0.023	0.567TrpPhe: 0.567 ± 0.021	0.988TrpGly: 0.988 ± 0.029	0.387TrpHis: 0.387 ± 0.018	0.7TrpIle: 0.7 ± 0.025	0.52TrpLys: 0.52 ± 0.021	2.369TrpLeu: 2.369 ± 0.054	0.487TrpMet: 0.487 ± 0.02	0.509TrpAsn: 0.509 ± 0.017	0.822TrpPro: 0.822 ± 0.026	1.006TrpGln: 1.006 ± 0.028	1.402TrpArg: 1.402 ± 0.035	0.913TrpSer: 0.913 ± 0.024	0.802TrpThr: 0.802 ± 0.024	1.053TrpVal: 1.053 ± 0.026	0.366TrpTrp: 0.366 ± 0.018	0.359TrpTyr: 0.359 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.715TyrAla: 2.715 ± 0.049	0.194TyrCys: 0.194 ± 0.012	1.378TyrAsp: 1.378 ± 0.039	1.094TyrGlu: 1.094 ± 0.028	0.838TyrPhe: 0.838 ± 0.026	1.993TyrGly: 1.993 ± 0.04	0.462TyrHis: 0.462 ± 0.018	0.782TyrIle: 0.782 ± 0.026	0.52TyrLys: 0.52 ± 0.02	2.499TyrLeu: 2.499 ± 0.048	0.387TyrMet: 0.387 ± 0.017	0.691TyrAsn: 0.691 ± 0.028	1.149TyrPro: 1.149 ± 0.033	1.004TyrGln: 1.004 ± 0.03	1.95TyrArg: 1.95 ± 0.045	1.295TyrSer: 1.295 ± 0.033	1.247TyrThr: 1.247 ± 0.036	1.629TyrVal: 1.629 ± 0.039	0.434TyrTrp: 0.434 ± 0.019	0.677TyrTyr: 0.677 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4365 proteins (1427787 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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