Amino acid dipepetide frequency for Beihai tombus-like virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.126AlaAla: 7.126 ± 1.399
0.792AlaCys: 0.792 ± 0.577
5.542AlaAsp: 5.542 ± 2.243
3.959AlaGlu: 3.959 ± 1.213
3.959AlaPhe: 3.959 ± 1.184
5.542AlaGly: 5.542 ± 1.391
3.167AlaHis: 3.167 ± 0.569
2.375AlaIle: 2.375 ± 1.368
7.126AlaLys: 7.126 ± 1.399
4.751AlaLeu: 4.751 ± 1.655
0.792AlaMet: 0.792 ± 0.607
2.375AlaAsn: 2.375 ± 1.368
1.584AlaPro: 1.584 ± 1.154
2.375AlaGln: 2.375 ± 1.153
4.751AlaArg: 4.751 ± 1.655
2.375AlaSer: 2.375 ± 0.828
6.334AlaThr: 6.334 ± 2.214
3.959AlaVal: 3.959 ± 1.101
1.584AlaTrp: 1.584 ± 1.178
0.792AlaTyr: 0.792 ± 0.589
0.0AlaXaa: 0.0 ± 0.0
Cys
0.792CysAla: 0.792 ± 0.589
0.0CysCys: 0.0 ± 0.0
1.584CysAsp: 1.584 ± 0.741
1.584CysGlu: 1.584 ± 1.154
0.0CysPhe: 0.0 ± 0.0
1.584CysGly: 1.584 ± 1.154
0.0CysHis: 0.0 ± 0.0
0.792CysIle: 0.792 ± 0.589
1.584CysLys: 1.584 ± 0.428
1.584CysLeu: 1.584 ± 1.178
0.0CysMet: 0.0 ± 0.0
0.792CysAsn: 0.792 ± 0.749
1.584CysPro: 1.584 ± 1.154
0.0CysGln: 0.0 ± 0.0
0.792CysArg: 0.792 ± 0.577
0.792CysSer: 0.792 ± 0.589
0.792CysThr: 0.792 ± 0.577
0.792CysVal: 0.792 ± 0.589
1.584CysTrp: 1.584 ± 0.782
0.792CysTyr: 0.792 ± 0.589
0.0CysXaa: 0.0 ± 0.0
Asp
7.126AspAla: 7.126 ± 2.685
0.792AspCys: 0.792 ± 0.577
3.167AspAsp: 3.167 ± 0.537
3.959AspGlu: 3.959 ± 1.101
4.751AspPhe: 4.751 ± 0.634
3.167AspGly: 3.167 ± 0.569
2.375AspHis: 2.375 ± 1.767
2.375AspIle: 2.375 ± 0.828
3.167AspLys: 3.167 ± 1.482
1.584AspLeu: 1.584 ± 0.428
1.584AspMet: 1.584 ± 0.782
0.792AspAsn: 0.792 ± 0.577
4.751AspPro: 4.751 ± 1.655
3.167AspGln: 3.167 ± 0.569
1.584AspArg: 1.584 ± 0.428
5.542AspSer: 5.542 ± 1.207
0.792AspThr: 0.792 ± 0.577
1.584AspVal: 1.584 ± 0.428
1.584AspTrp: 1.584 ± 1.154
3.167AspTyr: 3.167 ± 1.614
0.0AspXaa: 0.0 ± 0.0
Glu
1.584GluAla: 1.584 ± 0.428
0.0GluCys: 0.0 ± 0.0
0.792GluAsp: 0.792 ± 0.589
0.792GluGlu: 0.792 ± 0.749
3.167GluPhe: 3.167 ± 0.537
3.167GluGly: 3.167 ± 1.362
3.167GluHis: 3.167 ± 1.07
3.167GluIle: 3.167 ± 2.078
1.584GluLys: 1.584 ± 0.428
2.375GluLeu: 2.375 ± 1.767
0.792GluMet: 0.792 ± 0.577
1.584GluAsn: 1.584 ± 1.154
2.375GluPro: 2.375 ± 2.246
0.792GluGln: 0.792 ± 0.589
3.959GluArg: 3.959 ± 1.08
0.792GluSer: 0.792 ± 0.577
4.751GluThr: 4.751 ± 1.221
2.375GluVal: 2.375 ± 1.153
0.792GluTrp: 0.792 ± 0.589
3.959GluTyr: 3.959 ± 0.107
0.0GluXaa: 0.0 ± 0.0
Phe
1.584PheAla: 1.584 ± 1.154
1.584PheCys: 1.584 ± 0.741
2.375PheAsp: 2.375 ± 1.767
2.375PheGlu: 2.375 ± 0.321
0.0PhePhe: 0.0 ± 0.0
3.167PheGly: 3.167 ± 0.569
0.0PheHis: 0.0 ± 0.0
3.167PheIle: 3.167 ± 1.614
6.334PheLys: 6.334 ± 1.073
1.584PheLeu: 1.584 ± 1.178
1.584PheMet: 1.584 ± 0.428
0.0PheAsn: 0.0 ± 0.0
0.792PhePro: 0.792 ± 0.589
1.584PheGln: 1.584 ± 1.154
2.375PheArg: 2.375 ± 0.852
4.751PheSer: 4.751 ± 1.663
3.959PheThr: 3.959 ± 2.166
2.375PheVal: 2.375 ± 0.852
0.792PheTrp: 0.792 ± 0.577
1.584PheTyr: 1.584 ± 0.782
0.0PheXaa: 0.0 ± 0.0
Gly
3.959GlyAla: 3.959 ± 2.886
0.792GlyCys: 0.792 ± 0.577
3.959GlyAsp: 3.959 ± 1.213
0.792GlyGlu: 0.792 ± 0.589
3.167GlyPhe: 3.167 ± 1.401
5.542GlyGly: 5.542 ± 2.233
0.792GlyHis: 0.792 ± 0.589
6.334GlyIle: 6.334 ± 1.265
7.918GlyLys: 7.918 ± 0.215
9.501GlyLeu: 9.501 ± 2.815
0.792GlyMet: 0.792 ± 0.749
7.126GlyAsn: 7.126 ± 1.502
3.167GlyPro: 3.167 ± 2.309
1.584GlyGln: 1.584 ± 1.154
1.584GlyArg: 1.584 ± 0.741
4.751GlySer: 4.751 ± 0.643
3.959GlyThr: 3.959 ± 1.213
3.959GlyVal: 3.959 ± 1.041
1.584GlyTrp: 1.584 ± 1.154
3.959GlyTyr: 3.959 ± 0.107
0.0GlyXaa: 0.0 ± 0.0
His
4.751HisAla: 4.751 ± 0.643
0.792HisCys: 0.792 ± 0.589
1.584HisAsp: 1.584 ± 1.154
0.792HisGlu: 0.792 ± 0.749
3.167HisPhe: 3.167 ± 0.569
1.584HisGly: 1.584 ± 1.154
1.584HisHis: 1.584 ± 0.782
0.792HisIle: 0.792 ± 0.589
3.167HisLys: 3.167 ± 1.07
0.792HisLeu: 0.792 ± 0.589
1.584HisMet: 1.584 ± 0.782
1.584HisAsn: 1.584 ± 0.741
0.792HisPro: 0.792 ± 0.589
0.0HisGln: 0.0 ± 0.0
2.375HisArg: 2.375 ± 1.767
2.375HisSer: 2.375 ± 0.852
3.167HisThr: 3.167 ± 1.482
1.584HisVal: 1.584 ± 0.782
1.584HisTrp: 1.584 ± 0.428
1.584HisTyr: 1.584 ± 1.178
0.0HisXaa: 0.0 ± 0.0
Ile
3.167IleAla: 3.167 ± 0.569
1.584IleCys: 1.584 ± 0.741
1.584IleAsp: 1.584 ± 0.782
2.375IleGlu: 2.375 ± 1.419
1.584IlePhe: 1.584 ± 1.154
3.167IleGly: 3.167 ± 2.356
2.375IleHis: 2.375 ± 0.321
3.959IleIle: 3.959 ± 0.985
3.167IleLys: 3.167 ± 0.537
3.167IleLeu: 3.167 ± 0.855
1.584IleMet: 1.584 ± 1.178
4.751IleAsn: 4.751 ± 1.666
5.542IlePro: 5.542 ± 0.66
1.584IleGln: 1.584 ± 1.178
2.375IleArg: 2.375 ± 2.246
3.959IleSer: 3.959 ± 1.184
6.334IleThr: 6.334 ± 1.073
2.375IleVal: 2.375 ± 1.109
0.0IleTrp: 0.0 ± 0.0
0.792IleTyr: 0.792 ± 0.749
0.0IleXaa: 0.0 ± 0.0
Lys
4.751LysAla: 4.751 ± 0.643
1.584LysCys: 1.584 ± 0.428
3.167LysAsp: 3.167 ± 2.356
2.375LysGlu: 2.375 ± 1.368
4.751LysPhe: 4.751 ± 2.219
3.959LysGly: 3.959 ± 0.107
1.584LysHis: 1.584 ± 0.782
5.542LysIle: 5.542 ± 1.714
7.918LysLys: 7.918 ± 3.849
5.542LysLeu: 5.542 ± 0.534
0.792LysMet: 0.792 ± 0.589
0.792LysAsn: 0.792 ± 0.589
4.751LysPro: 4.751 ± 1.704
0.792LysGln: 0.792 ± 0.749
4.751LysArg: 4.751 ± 1.704
4.751LysSer: 4.751 ± 2.735
8.709LysThr: 8.709 ± 1.627
4.751LysVal: 4.751 ± 1.3
2.375LysTrp: 2.375 ± 0.321
3.167LysTyr: 3.167 ± 1.482
0.0LysXaa: 0.0 ± 0.0
Leu
7.126LeuAla: 7.126 ± 1.461
0.792LeuCys: 0.792 ± 0.577
7.126LeuAsp: 7.126 ± 2.36
0.792LeuGlu: 0.792 ± 0.577
0.792LeuPhe: 0.792 ± 0.589
3.959LeuGly: 3.959 ± 0.107
3.167LeuHis: 3.167 ± 1.401
3.167LeuIle: 3.167 ± 0.569
3.959LeuLys: 3.959 ± 1.08
6.334LeuLeu: 6.334 ± 1.71
1.584LeuMet: 1.584 ± 0.428
5.542LeuAsn: 5.542 ± 2.791
2.375LeuPro: 2.375 ± 2.246
5.542LeuGln: 5.542 ± 3.136
2.375LeuArg: 2.375 ± 0.321
5.542LeuSer: 5.542 ± 1.607
2.375LeuThr: 2.375 ± 0.852
3.959LeuVal: 3.959 ± 1.921
0.0LeuTrp: 0.0 ± 0.0
2.375LeuTyr: 2.375 ± 1.767
0.0LeuXaa: 0.0 ± 0.0
Met
1.584MetAla: 1.584 ± 0.782
0.0MetCys: 0.0 ± 0.0
2.375MetAsp: 2.375 ± 1.153
3.167MetGlu: 3.167 ± 1.401
1.584MetPhe: 1.584 ± 1.498
0.792MetGly: 0.792 ± 0.577
0.0MetHis: 0.0 ± 0.0
1.584MetIle: 1.584 ± 0.741
1.584MetLys: 1.584 ± 1.178
0.792MetLeu: 0.792 ± 0.749
0.792MetMet: 0.792 ± 0.589
0.792MetAsn: 0.792 ± 0.577
1.584MetPro: 1.584 ± 1.178
0.792MetGln: 0.792 ± 0.577
0.792MetArg: 0.792 ± 0.589
0.792MetSer: 0.792 ± 0.589
1.584MetThr: 1.584 ± 0.428
1.584MetVal: 1.584 ± 0.741
0.792MetTrp: 0.792 ± 0.589
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.792AsnAla: 0.792 ± 0.749
1.584AsnCys: 1.584 ± 1.178
3.167AsnAsp: 3.167 ± 1.648
3.167AsnGlu: 3.167 ± 0.537
0.0AsnPhe: 0.0 ± 0.0
6.334AsnGly: 6.334 ± 1.073
1.584AsnHis: 1.584 ± 0.741
2.375AsnIle: 2.375 ± 1.368
3.959AsnLys: 3.959 ± 1.101
2.375AsnLeu: 2.375 ± 0.321
1.584AsnMet: 1.584 ± 0.741
3.167AsnAsn: 3.167 ± 0.537
0.792AsnPro: 0.792 ± 0.577
3.167AsnGln: 3.167 ± 2.078
3.167AsnArg: 3.167 ± 1.401
2.375AsnSer: 2.375 ± 0.828
4.751AsnThr: 4.751 ± 0.634
2.375AsnVal: 2.375 ± 1.368
2.375AsnTrp: 2.375 ± 1.153
0.792AsnTyr: 0.792 ± 0.749
0.0AsnXaa: 0.0 ± 0.0
Pro
2.375ProAla: 2.375 ± 1.732
0.792ProCys: 0.792 ± 0.749
3.167ProAsp: 3.167 ± 0.569
3.959ProGlu: 3.959 ± 0.107
2.375ProPhe: 2.375 ± 0.852
3.167ProGly: 3.167 ± 0.855
2.375ProHis: 2.375 ± 0.321
2.375ProIle: 2.375 ± 0.321
2.375ProLys: 2.375 ± 1.419
4.751ProLeu: 4.751 ± 0.634
0.792ProMet: 0.792 ± 0.589
1.584ProAsn: 1.584 ± 0.428
0.0ProPro: 0.0 ± 0.0
2.375ProGln: 2.375 ± 1.419
3.167ProArg: 3.167 ± 0.855
0.0ProSer: 0.0 ± 0.0
3.959ProThr: 3.959 ± 1.885
3.959ProVal: 3.959 ± 1.101
2.375ProTrp: 2.375 ± 0.852
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.751GlnAla: 4.751 ± 0.634
0.792GlnCys: 0.792 ± 0.589
0.792GlnAsp: 0.792 ± 0.577
0.792GlnGlu: 0.792 ± 0.589
0.0GlnPhe: 0.0 ± 0.0
2.375GlnGly: 2.375 ± 1.419
3.167GlnHis: 3.167 ± 1.565
2.375GlnIle: 2.375 ± 0.321
1.584GlnLys: 1.584 ± 1.154
6.334GlnLeu: 6.334 ± 1.265
0.0GlnMet: 0.0 ± 0.0
2.375GlnAsn: 2.375 ± 1.109
3.167GlnPro: 3.167 ± 1.565
2.375GlnGln: 2.375 ± 0.852
2.375GlnArg: 2.375 ± 1.419
3.167GlnSer: 3.167 ± 1.648
0.792GlnThr: 0.792 ± 0.589
0.792GlnVal: 0.792 ± 0.749
0.0GlnTrp: 0.0 ± 0.0
0.792GlnTyr: 0.792 ± 0.589
0.0GlnXaa: 0.0 ± 0.0
Arg
3.959ArgAla: 3.959 ± 2.162
0.0ArgCys: 0.0 ± 0.0
0.792ArgAsp: 0.792 ± 0.589
0.0ArgGlu: 0.0 ± 0.0
3.167ArgPhe: 3.167 ± 0.569
3.959ArgGly: 3.959 ± 1.921
0.792ArgHis: 0.792 ± 0.589
2.375ArgIle: 2.375 ± 0.828
3.167ArgLys: 3.167 ± 1.482
9.501ArgLeu: 9.501 ± 1.61
2.375ArgMet: 2.375 ± 1.501
3.167ArgAsn: 3.167 ± 0.537
2.375ArgPro: 2.375 ± 1.767
2.375ArgGln: 2.375 ± 0.321
2.375ArgArg: 2.375 ± 0.828
1.584ArgSer: 1.584 ± 0.428
3.167ArgThr: 3.167 ± 1.482
5.542ArgVal: 5.542 ± 1.607
0.792ArgTrp: 0.792 ± 0.577
1.584ArgTyr: 1.584 ± 0.428
0.0ArgXaa: 0.0 ± 0.0
Ser
3.167SerAla: 3.167 ± 1.648
0.0SerCys: 0.0 ± 0.0
4.751SerAsp: 4.751 ± 1.663
2.375SerGlu: 2.375 ± 1.419
1.584SerPhe: 1.584 ± 0.741
7.918SerGly: 7.918 ± 1.303
2.375SerHis: 2.375 ± 1.109
4.751SerIle: 4.751 ± 1.704
3.167SerLys: 3.167 ± 1.362
1.584SerLeu: 1.584 ± 1.498
1.584SerMet: 1.584 ± 0.782
3.167SerAsn: 3.167 ± 0.855
4.751SerPro: 4.751 ± 3.463
0.792SerGln: 0.792 ± 0.577
3.959SerArg: 3.959 ± 1.184
2.375SerSer: 2.375 ± 0.321
3.959SerThr: 3.959 ± 1.184
4.751SerVal: 4.751 ± 1.655
1.584SerTrp: 1.584 ± 1.154
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.334ThrAla: 6.334 ± 0.919
1.584ThrCys: 1.584 ± 0.428
2.375ThrAsp: 2.375 ± 1.109
3.959ThrGlu: 3.959 ± 0.985
1.584ThrPhe: 1.584 ± 1.154
6.334ThrGly: 6.334 ± 1.139
2.375ThrHis: 2.375 ± 1.153
2.375ThrIle: 2.375 ± 0.828
7.918ThrLys: 7.918 ± 2.759
2.375ThrLeu: 2.375 ± 0.852
1.584ThrMet: 1.584 ± 0.782
2.375ThrAsn: 2.375 ± 0.828
2.375ThrPro: 2.375 ± 0.852
3.959ThrGln: 3.959 ± 1.885
3.959ThrArg: 3.959 ± 1.213
2.375ThrSer: 2.375 ± 1.419
7.126ThrThr: 7.126 ± 2.739
5.542ThrVal: 5.542 ± 1.207
1.584ThrTrp: 1.584 ± 1.178
2.375ThrTyr: 2.375 ± 1.368
0.0ThrXaa: 0.0 ± 0.0
Val
3.959ValAla: 3.959 ± 0.985
2.375ValCys: 2.375 ± 0.828
4.751ValAsp: 4.751 ± 0.634
0.792ValGlu: 0.792 ± 0.589
3.959ValPhe: 3.959 ± 1.213
7.126ValGly: 7.126 ± 0.962
2.375ValHis: 2.375 ± 0.828
3.167ValIle: 3.167 ± 0.855
3.959ValLys: 3.959 ± 1.973
2.375ValLeu: 2.375 ± 1.153
1.584ValMet: 1.584 ± 1.178
5.542ValAsn: 5.542 ± 0.534
2.375ValPro: 2.375 ± 1.419
1.584ValGln: 1.584 ± 1.498
3.167ValArg: 3.167 ± 1.07
3.167ValSer: 3.167 ± 0.569
1.584ValThr: 1.584 ± 1.154
2.375ValVal: 2.375 ± 1.732
2.375ValTrp: 2.375 ± 1.153
3.167ValTyr: 3.167 ± 0.855
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.375TrpAsp: 2.375 ± 1.153
1.584TrpGlu: 1.584 ± 1.178
1.584TrpPhe: 1.584 ± 0.782
0.792TrpGly: 0.792 ± 0.577
1.584TrpHis: 1.584 ± 1.178
2.375TrpIle: 2.375 ± 0.321
0.0TrpLys: 0.0 ± 0.0
0.792TrpLeu: 0.792 ± 0.589
0.792TrpMet: 0.792 ± 0.473
0.792TrpAsn: 0.792 ± 0.577
0.0TrpPro: 0.0 ± 0.0
2.375TrpGln: 2.375 ± 1.153
2.375TrpArg: 2.375 ± 0.828
2.375TrpSer: 2.375 ± 1.732
1.584TrpThr: 1.584 ± 1.154
3.167TrpVal: 3.167 ± 1.401
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.375TyrAla: 2.375 ± 1.109
1.584TyrCys: 1.584 ± 1.154
1.584TyrAsp: 1.584 ± 0.741
2.375TyrGlu: 2.375 ± 0.321
0.792TyrPhe: 0.792 ± 0.749
1.584TyrGly: 1.584 ± 1.178
0.792TyrHis: 0.792 ± 0.589
0.0TyrIle: 0.0 ± 0.0
3.167TyrLys: 3.167 ± 1.401
0.792TyrLeu: 0.792 ± 0.577
0.0TyrMet: 0.0 ± 0.0
1.584TyrAsn: 1.584 ± 1.498
0.792TyrPro: 0.792 ± 0.749
1.584TyrGln: 1.584 ± 1.498
1.584TyrArg: 1.584 ± 1.178
4.751TyrSer: 4.751 ± 0.627
0.792TyrThr: 0.792 ± 0.577
3.959TyrVal: 3.959 ± 2.945
0.792TyrTrp: 0.792 ± 0.589
1.584TyrTyr: 1.584 ± 0.741
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1264 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski