Amino acid dipepetide frequency for Rhizoctonia solani

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.955AlaAla: 7.955 ± 0.056	1.06AlaCys: 1.06 ± 0.014	3.754AlaAsp: 3.754 ± 0.029	4.624AlaGlu: 4.624 ± 0.037	3.015AlaPhe: 3.015 ± 0.023	5.591AlaGly: 5.591 ± 0.043	2.0AlaHis: 2.0 ± 0.019	4.231AlaIle: 4.231 ± 0.031	3.895AlaLys: 3.895 ± 0.033	8.106AlaLeu: 8.106 ± 0.046	1.799AlaMet: 1.799 ± 0.017	2.948AlaAsn: 2.948 ± 0.023	5.581AlaPro: 5.581 ± 0.051	3.453AlaGln: 3.453 ± 0.03	5.247AlaArg: 5.247 ± 0.035	7.283AlaSer: 7.283 ± 0.041	5.342AlaThr: 5.342 ± 0.033	4.829AlaVal: 4.829 ± 0.033	1.138AlaTrp: 1.138 ± 0.015	2.321AlaTyr: 2.321 ± 0.021	0.009AlaXaa: 0.009 ± 0.001
Cys	0.935CysAla: 0.935 ± 0.015	0.196CysCys: 0.196 ± 0.007	0.669CysAsp: 0.669 ± 0.011	0.589CysGlu: 0.589 ± 0.012	0.459CysPhe: 0.459 ± 0.009	0.872CysGly: 0.872 ± 0.014	0.292CysHis: 0.292 ± 0.007	0.701CysIle: 0.701 ± 0.013	0.505CysLys: 0.505 ± 0.009	1.108CysLeu: 1.108 ± 0.016	0.254CysMet: 0.254 ± 0.008	0.413CysAsn: 0.413 ± 0.007	0.677CysPro: 0.677 ± 0.013	0.412CysGln: 0.412 ± 0.009	0.675CysArg: 0.675 ± 0.011	0.894CysSer: 0.894 ± 0.013	0.767CysThr: 0.767 ± 0.013	0.823CysVal: 0.823 ± 0.013	0.225CysTrp: 0.225 ± 0.006	0.363CysTyr: 0.363 ± 0.01	0.001CysXaa: 0.001 ± 0.0
Asp	4.503AspAla: 4.503 ± 0.028	0.583AspCys: 0.583 ± 0.011	3.574AspAsp: 3.574 ± 0.03	4.142AspGlu: 4.142 ± 0.032	1.909AspPhe: 1.909 ± 0.022	3.94AspGly: 3.94 ± 0.033	1.226AspHis: 1.226 ± 0.016	2.991AspIle: 2.991 ± 0.027	2.232AspLys: 2.232 ± 0.023	4.784AspLeu: 4.784 ± 0.033	1.18AspMet: 1.18 ± 0.014	1.784AspAsn: 1.784 ± 0.017	3.46AspPro: 3.46 ± 0.024	1.868AspGln: 1.868 ± 0.02	2.874AspArg: 2.874 ± 0.028	4.111AspSer: 4.111 ± 0.028	2.965AspThr: 2.965 ± 0.024	3.47AspVal: 3.47 ± 0.026	0.852AspTrp: 0.852 ± 0.011	1.512AspTyr: 1.512 ± 0.015	0.004AspXaa: 0.004 ± 0.001
Glu	4.841GluAla: 4.841 ± 0.041	0.69GluCys: 0.69 ± 0.014	3.724GluAsp: 3.724 ± 0.029	4.595GluGlu: 4.595 ± 0.044	1.862GluPhe: 1.862 ± 0.018	3.467GluGly: 3.467 ± 0.029	1.474GluHis: 1.474 ± 0.016	2.901GluIle: 2.901 ± 0.027	2.941GluLys: 2.941 ± 0.029	5.547GluLeu: 5.547 ± 0.037	1.259GluMet: 1.259 ± 0.015	1.915GluAsn: 1.915 ± 0.019	3.079GluPro: 3.079 ± 0.029	2.355GluGln: 2.355 ± 0.024	3.904GluArg: 3.904 ± 0.032	4.247GluSer: 4.247 ± 0.031	3.095GluThr: 3.095 ± 0.028	3.363GluVal: 3.363 ± 0.029	0.967GluTrp: 0.967 ± 0.012	1.672GluTyr: 1.672 ± 0.017	0.003GluXaa: 0.003 ± 0.001
Phe	2.865PheAla: 2.865 ± 0.021	0.466PheCys: 0.466 ± 0.009	2.124PheAsp: 2.124 ± 0.021	1.992PheGlu: 1.992 ± 0.02	1.306PhePhe: 1.306 ± 0.016	2.792PheGly: 2.792 ± 0.027	0.774PheHis: 0.774 ± 0.012	1.759PheIle: 1.759 ± 0.021	1.542PheLys: 1.542 ± 0.018	2.953PheLeu: 2.953 ± 0.022	0.724PheMet: 0.724 ± 0.012	1.387PheAsn: 1.387 ± 0.015	1.802PhePro: 1.802 ± 0.018	1.205PheGln: 1.205 ± 0.014	1.802PheArg: 1.802 ± 0.016	2.931PheSer: 2.931 ± 0.026	2.057PheThr: 2.057 ± 0.019	2.327PheVal: 2.327 ± 0.02	0.558PheTrp: 0.558 ± 0.011	0.95PheTyr: 0.95 ± 0.013	0.002PheXaa: 0.002 ± 0.001
Gly	5.363GlyAla: 5.363 ± 0.042	0.855GlyCys: 0.855 ± 0.014	3.386GlyAsp: 3.386 ± 0.023	3.427GlyGlu: 3.427 ± 0.029	2.406GlyPhe: 2.406 ± 0.022	5.357GlyGly: 5.357 ± 0.051	1.793GlyHis: 1.793 ± 0.02	3.316GlyIle: 3.316 ± 0.026	3.273GlyLys: 3.273 ± 0.028	5.751GlyLeu: 5.751 ± 0.035	1.549GlyMet: 1.549 ± 0.021	2.488GlyAsn: 2.488 ± 0.028	3.517GlyPro: 3.517 ± 0.029	2.44GlyGln: 2.44 ± 0.024	3.898GlyArg: 3.898 ± 0.027	5.975GlySer: 5.975 ± 0.043	4.454GlyThr: 4.454 ± 0.03	4.343GlyVal: 4.343 ± 0.032	1.127GlyTrp: 1.127 ± 0.015	1.974GlyTyr: 1.974 ± 0.021	0.007GlyXaa: 0.007 ± 0.001
His	2.021HisAla: 2.021 ± 0.018	0.306HisCys: 0.306 ± 0.007	1.269HisAsp: 1.269 ± 0.016	1.367HisGlu: 1.367 ± 0.015	0.876HisPhe: 0.876 ± 0.012	1.599HisGly: 1.599 ± 0.018	0.745HisHis: 0.745 ± 0.013	1.365HisIle: 1.365 ± 0.015	0.921HisLys: 0.921 ± 0.013	2.222HisLeu: 2.222 ± 0.022	0.476HisMet: 0.476 ± 0.009	0.845HisAsn: 0.845 ± 0.011	1.908HisPro: 1.908 ± 0.025	0.89HisGln: 0.89 ± 0.014	1.452HisArg: 1.452 ± 0.017	2.019HisSer: 2.019 ± 0.022	1.628HisThr: 1.628 ± 0.018	1.518HisVal: 1.518 ± 0.016	0.341HisTrp: 0.341 ± 0.007	0.711HisTyr: 0.711 ± 0.01	0.001HisXaa: 0.001 ± 0.0
Ile	4.256IleAla: 4.256 ± 0.03	0.689IleCys: 0.689 ± 0.012	2.856IleAsp: 2.856 ± 0.023	2.954IleGlu: 2.954 ± 0.025	1.753IlePhe: 1.753 ± 0.019	3.181IleGly: 3.181 ± 0.029	1.278IleHis: 1.278 ± 0.014	2.552IleIle: 2.552 ± 0.025	2.221IleLys: 2.221 ± 0.022	4.274IleLeu: 4.274 ± 0.033	0.973IleMet: 0.973 ± 0.013	1.782IleAsn: 1.782 ± 0.018	3.278IlePro: 3.278 ± 0.026	1.986IleGln: 1.986 ± 0.019	2.921IleArg: 2.921 ± 0.026	4.007IleSer: 4.007 ± 0.03	2.926IleThr: 2.926 ± 0.022	3.259IleVal: 3.259 ± 0.026	0.808IleTrp: 0.808 ± 0.014	1.425IleTyr: 1.425 ± 0.016	0.005IleXaa: 0.005 ± 0.001
Lys	3.941LysAla: 3.941 ± 0.033	0.514LysCys: 0.514 ± 0.01	2.501LysAsp: 2.501 ± 0.023	2.886LysGlu: 2.886 ± 0.031	1.393LysPhe: 1.393 ± 0.016	2.725LysGly: 2.725 ± 0.023	1.163LysHis: 1.163 ± 0.015	2.107LysIle: 2.107 ± 0.02	2.622LysLys: 2.622 ± 0.033	4.1LysLeu: 4.1 ± 0.027	0.828LysMet: 0.828 ± 0.011	1.576LysAsn: 1.576 ± 0.018	2.769LysPro: 2.769 ± 0.03	1.712LysGln: 1.712 ± 0.017	3.251LysArg: 3.251 ± 0.031	3.472LysSer: 3.472 ± 0.027	2.512LysThr: 2.512 ± 0.021	2.577LysVal: 2.577 ± 0.022	0.65LysTrp: 0.65 ± 0.011	1.282LysTyr: 1.282 ± 0.016	0.003LysXaa: 0.003 ± 0.001
Leu	8.22LeuAla: 8.22 ± 0.041	1.208LeuCys: 1.208 ± 0.017	5.102LeuAsp: 5.102 ± 0.033	5.469LeuGlu: 5.469 ± 0.037	3.136LeuPhe: 3.136 ± 0.025	6.099LeuGly: 6.099 ± 0.033	2.252LeuHis: 2.252 ± 0.021	3.867LeuIle: 3.867 ± 0.031	4.109LeuLys: 4.109 ± 0.03	7.778LeuLeu: 7.778 ± 0.055	1.611LeuMet: 1.611 ± 0.017	3.158LeuAsn: 3.158 ± 0.023	5.699LeuPro: 5.699 ± 0.037	3.338LeuGln: 3.338 ± 0.025	5.416LeuArg: 5.416 ± 0.032	7.347LeuSer: 7.347 ± 0.042	4.833LeuThr: 4.833 ± 0.028	5.882LeuVal: 5.882 ± 0.034	1.238LeuTrp: 1.238 ± 0.016	2.241LeuTyr: 2.241 ± 0.02	0.008LeuXaa: 0.008 ± 0.001
Met	1.796MetAla: 1.796 ± 0.019	0.245MetCys: 0.245 ± 0.006	1.133MetAsp: 1.133 ± 0.014	1.098MetGlu: 1.098 ± 0.014	0.76MetPhe: 0.76 ± 0.012	1.299MetGly: 1.299 ± 0.021	0.496MetHis: 0.496 ± 0.009	1.009MetIle: 1.009 ± 0.015	0.895MetLys: 0.895 ± 0.013	1.793MetLeu: 1.793 ± 0.017	0.486MetMet: 0.486 ± 0.01	0.836MetAsn: 0.836 ± 0.014	1.148MetPro: 1.148 ± 0.016	0.714MetGln: 0.714 ± 0.012	1.263MetArg: 1.263 ± 0.016	1.895MetSer: 1.895 ± 0.017	1.203MetThr: 1.203 ± 0.015	1.232MetVal: 1.232 ± 0.015	0.287MetTrp: 0.287 ± 0.007	0.476MetTyr: 0.476 ± 0.009	0.001MetXaa: 0.001 ± 0.0
Asn	3.104AsnAla: 3.104 ± 0.024	0.393AsnCys: 0.393 ± 0.008	1.867AsnAsp: 1.867 ± 0.018	1.954AsnGlu: 1.954 ± 0.019	1.183AsnPhe: 1.183 ± 0.016	2.734AsnGly: 2.734 ± 0.025	0.821AsnHis: 0.821 ± 0.013	2.025AsnIle: 2.025 ± 0.019	1.568AsnLys: 1.568 ± 0.016	3.243AsnLeu: 3.243 ± 0.025	0.784AsnMet: 0.784 ± 0.013	1.521AsnAsn: 1.521 ± 0.019	2.557AsnPro: 2.557 ± 0.02	1.369AsnGln: 1.369 ± 0.016	1.882AsnArg: 1.882 ± 0.017	2.811AsnSer: 2.811 ± 0.025	2.335AsnThr: 2.335 ± 0.023	2.321AsnVal: 2.321 ± 0.02	0.531AsnTrp: 0.531 ± 0.009	1.013AsnTyr: 1.013 ± 0.014	0.003AsnXaa: 0.003 ± 0.001
Pro	5.622ProAla: 5.622 ± 0.05	0.476ProCys: 0.476 ± 0.011	3.59ProAsp: 3.59 ± 0.029	4.006ProGlu: 4.006 ± 0.03	1.997ProPhe: 1.997 ± 0.023	4.163ProGly: 4.163 ± 0.038	1.541ProHis: 1.541 ± 0.018	2.928ProIle: 2.928 ± 0.026	2.689ProLys: 2.689 ± 0.023	4.996ProLeu: 4.996 ± 0.033	1.065ProMet: 1.065 ± 0.015	2.532ProAsn: 2.532 ± 0.022	6.151ProPro: 6.151 ± 0.078	2.383ProGln: 2.383 ± 0.033	3.604ProArg: 3.604 ± 0.031	6.523ProSer: 6.523 ± 0.053	4.843ProThr: 4.843 ± 0.04	3.958ProVal: 3.958 ± 0.03	0.662ProTrp: 0.662 ± 0.012	1.54ProTyr: 1.54 ± 0.02	0.01ProXaa: 0.01 ± 0.001
Gln	3.404GlnAla: 3.404 ± 0.03	0.433GlnCys: 0.433 ± 0.01	1.881GlnAsp: 1.881 ± 0.017	2.064GlnGlu: 2.064 ± 0.018	1.232GlnPhe: 1.232 ± 0.017	2.221GlnGly: 2.221 ± 0.022	0.989GlnHis: 0.989 ± 0.014	1.821GlnIle: 1.821 ± 0.019	1.544GlnLys: 1.544 ± 0.017	3.704GlnLeu: 3.704 ± 0.03	0.761GlnMet: 0.761 ± 0.013	1.38GlnAsn: 1.38 ± 0.017	2.621GlnPro: 2.621 ± 0.034	1.841GlnGln: 1.841 ± 0.033	2.39GlnArg: 2.39 ± 0.018	2.988GlnSer: 2.988 ± 0.025	2.292GlnThr: 2.292 ± 0.017	2.328GlnVal: 2.328 ± 0.023	0.533GlnTrp: 0.533 ± 0.01	1.065GlnTyr: 1.065 ± 0.014	0.002GlnXaa: 0.002 ± 0.001
Arg	5.188ArgAla: 5.188 ± 0.032	0.732ArgCys: 0.732 ± 0.011	3.133ArgAsp: 3.133 ± 0.028	3.549ArgGlu: 3.549 ± 0.03	2.107ArgPhe: 2.107 ± 0.021	3.58ArgGly: 3.58 ± 0.029	1.446ArgHis: 1.446 ± 0.017	3.038ArgIle: 3.038 ± 0.024	2.961ArgLys: 2.961 ± 0.027	5.472ArgLeu: 5.472 ± 0.039	1.344ArgMet: 1.344 ± 0.014	2.057ArgAsn: 2.057 ± 0.022	3.672ArgPro: 3.672 ± 0.033	2.256ArgGln: 2.256 ± 0.019	4.625ArgArg: 4.625 ± 0.035	4.954ArgSer: 4.954 ± 0.038	3.539ArgThr: 3.539 ± 0.025	3.722ArgVal: 3.722 ± 0.027	0.923ArgTrp: 0.923 ± 0.014	1.661ArgTyr: 1.661 ± 0.018	0.007ArgXaa: 0.007 ± 0.001
Ser	6.706SerAla: 6.706 ± 0.038	0.88SerCys: 0.88 ± 0.015	4.347SerAsp: 4.347 ± 0.03	4.252SerGlu: 4.252 ± 0.028	2.846SerPhe: 2.846 ± 0.019	5.952SerGly: 5.952 ± 0.043	2.049SerHis: 2.049 ± 0.021	4.13SerIle: 4.13 ± 0.027	3.52SerLys: 3.52 ± 0.028	7.133SerLeu: 7.133 ± 0.043	1.585SerMet: 1.585 ± 0.017	3.141SerAsn: 3.141 ± 0.023	6.155SerPro: 6.155 ± 0.058	3.147SerGln: 3.147 ± 0.03	5.104SerArg: 5.104 ± 0.034	8.664SerSer: 8.664 ± 0.066	6.001SerThr: 6.001 ± 0.042	5.08SerVal: 5.08 ± 0.034	1.025SerTrp: 1.025 ± 0.014	2.139SerTyr: 2.139 ± 0.022	0.008SerXaa: 0.008 ± 0.001
Thr	4.792ThrAla: 4.792 ± 0.031	0.724ThrCys: 0.724 ± 0.012	2.812ThrAsp: 2.812 ± 0.021	3.013ThrGlu: 3.013 ± 0.023	2.157ThrPhe: 2.157 ± 0.018	4.454ThrGly: 4.454 ± 0.033	1.523ThrHis: 1.523 ± 0.018	3.361ThrIle: 3.361 ± 0.026	2.51ThrLys: 2.51 ± 0.022	5.511ThrLeu: 5.511 ± 0.034	1.144ThrMet: 1.144 ± 0.014	2.253ThrAsn: 2.253 ± 0.019	4.996ThrPro: 4.996 ± 0.047	2.189ThrGln: 2.189 ± 0.023	3.64ThrArg: 3.64 ± 0.029	5.639ThrSer: 5.639 ± 0.038	4.484ThrThr: 4.484 ± 0.038	3.672ThrVal: 3.672 ± 0.027	0.873ThrTrp: 0.873 ± 0.014	1.695ThrTyr: 1.695 ± 0.021	0.007ThrXaa: 0.007 ± 0.001
Val	5.305ValAla: 5.305 ± 0.036	0.813ValCys: 0.813 ± 0.014	3.489ValAsp: 3.489 ± 0.025	3.636ValGlu: 3.636 ± 0.032	2.292ValPhe: 2.292 ± 0.021	3.866ValGly: 3.866 ± 0.028	1.582ValHis: 1.582 ± 0.019	3.087ValIle: 3.087 ± 0.024	2.802ValLys: 2.802 ± 0.023	5.739ValLeu: 5.739 ± 0.034	1.243ValMet: 1.243 ± 0.015	2.189ValAsn: 2.189 ± 0.021	4.083ValPro: 4.083 ± 0.032	2.44ValGln: 2.44 ± 0.02	3.551ValArg: 3.551 ± 0.024	4.796ValSer: 4.796 ± 0.031	3.554ValThr: 3.554 ± 0.029	4.402ValVal: 4.402 ± 0.031	1.055ValTrp: 1.055 ± 0.016	1.773ValTyr: 1.773 ± 0.018	0.007ValXaa: 0.007 ± 0.001
Trp	1.153TrpAla: 1.153 ± 0.015	0.204TrpCys: 0.204 ± 0.006	1.103TrpAsp: 1.103 ± 0.019	0.834TrpGlu: 0.834 ± 0.012	0.531TrpPhe: 0.531 ± 0.009	0.911TrpGly: 0.911 ± 0.013	0.344TrpHis: 0.344 ± 0.008	0.748TrpIle: 0.748 ± 0.012	0.763TrpLys: 0.763 ± 0.013	1.243TrpLeu: 1.243 ± 0.015	0.407TrpMet: 0.407 ± 0.009	0.712TrpAsn: 0.712 ± 0.011	0.59TrpPro: 0.59 ± 0.011	0.442TrpGln: 0.442 ± 0.009	0.896TrpArg: 0.896 ± 0.013	1.139TrpSer: 1.139 ± 0.016	0.912TrpThr: 0.912 ± 0.015	0.913TrpVal: 0.913 ± 0.013	0.258TrpTrp: 0.258 ± 0.007	0.398TrpTyr: 0.398 ± 0.008	0.001TrpXaa: 0.001 ± 0.0
Tyr	2.206TyrAla: 2.206 ± 0.022	0.36TyrCys: 0.36 ± 0.008	1.647TyrAsp: 1.647 ± 0.019	1.447TyrGlu: 1.447 ± 0.016	1.094TyrPhe: 1.094 ± 0.015	1.893TyrGly: 1.893 ± 0.02	0.69TyrHis: 0.69 ± 0.011	1.438TyrIle: 1.438 ± 0.016	1.069TyrLys: 1.069 ± 0.014	2.548TyrLeu: 2.548 ± 0.021	0.591TyrMet: 0.591 ± 0.009	1.099TyrAsn: 1.099 ± 0.014	1.528TyrPro: 1.528 ± 0.021	1.051TyrGln: 1.051 ± 0.015	1.561TyrArg: 1.561 ± 0.019	2.161TyrSer: 2.161 ± 0.019	1.7TyrThr: 1.7 ± 0.017	1.679TyrVal: 1.679 ± 0.017	0.45TyrTrp: 0.45 ± 0.009	0.878TyrTyr: 0.878 ± 0.015	0.002TyrXaa: 0.002 ± 0.001
Xaa	0.006XaaAla: 0.006 ± 0.001	0.002XaaCys: 0.002 ± 0.001	0.004XaaAsp: 0.004 ± 0.001	0.004XaaGlu: 0.004 ± 0.001	0.004XaaPhe: 0.004 ± 0.001	0.006XaaGly: 0.006 ± 0.001	0.002XaaHis: 0.002 ± 0.001	0.005XaaIle: 0.005 ± 0.001	0.002XaaLys: 0.002 ± 0.001	0.008XaaLeu: 0.008 ± 0.001	0.002XaaMet: 0.002 ± 0.001	0.002XaaAsn: 0.002 ± 0.001	0.008XaaPro: 0.008 ± 0.001	0.004XaaGln: 0.004 ± 0.001	0.006XaaArg: 0.006 ± 0.001	0.01XaaSer: 0.01 ± 0.001	0.006XaaThr: 0.006 ± 0.001	0.005XaaVal: 0.005 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.003XaaTyr: 0.003 ± 0.001	17.115XaaXaa: 17.115 ± 1.136

Statistics based on 11878 proteins (6275154 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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