Amino acid dipepetide frequency for Byssochlamys spectabilis (Paecilomyces variotii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.764AlaAla: 8.764 ± 0.065	0.975AlaCys: 0.975 ± 0.017	4.168AlaAsp: 4.168 ± 0.03	5.183AlaGlu: 5.183 ± 0.046	3.034AlaPhe: 3.034 ± 0.03	5.678AlaGly: 5.678 ± 0.043	1.714AlaHis: 1.714 ± 0.018	4.172AlaIle: 4.172 ± 0.034	3.99AlaLys: 3.99 ± 0.036	7.4AlaLeu: 7.4 ± 0.048	1.826AlaMet: 1.826 ± 0.018	2.802AlaAsn: 2.802 ± 0.026	4.605AlaPro: 4.605 ± 0.039	3.29AlaGln: 3.29 ± 0.031	4.906AlaArg: 4.906 ± 0.037	7.249AlaSer: 7.249 ± 0.053	4.942AlaThr: 4.942 ± 0.038	5.298AlaVal: 5.298 ± 0.039	1.079AlaTrp: 1.079 ± 0.017	2.141AlaTyr: 2.141 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	0.867CysAla: 0.867 ± 0.013	0.238CysCys: 0.238 ± 0.009	0.614CysAsp: 0.614 ± 0.013	0.58CysGlu: 0.58 ± 0.012	0.517CysPhe: 0.517 ± 0.011	0.891CysGly: 0.891 ± 0.016	0.331CysHis: 0.331 ± 0.009	0.689CysIle: 0.689 ± 0.013	0.489CysLys: 0.489 ± 0.013	1.251CysLeu: 1.251 ± 0.017	0.25CysMet: 0.25 ± 0.008	0.404CysAsn: 0.404 ± 0.009	0.648CysPro: 0.648 ± 0.012	0.436CysGln: 0.436 ± 0.01	0.772CysArg: 0.772 ± 0.013	0.928CysSer: 0.928 ± 0.017	0.628CysThr: 0.628 ± 0.012	0.745CysVal: 0.745 ± 0.013	0.192CysTrp: 0.192 ± 0.007	0.35CysTyr: 0.35 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.572AspAla: 4.572 ± 0.035	0.599AspCys: 0.599 ± 0.012	4.094AspAsp: 4.094 ± 0.039	4.58AspGlu: 4.58 ± 0.04	2.185AspPhe: 2.185 ± 0.022	3.965AspGly: 3.965 ± 0.033	1.226AspHis: 1.226 ± 0.018	3.296AspIle: 3.296 ± 0.029	2.383AspLys: 2.383 ± 0.025	5.047AspLeu: 5.047 ± 0.037	1.219AspMet: 1.219 ± 0.014	1.934AspAsn: 1.934 ± 0.018	3.44AspPro: 3.44 ± 0.032	1.877AspGln: 1.877 ± 0.02	3.183AspArg: 3.183 ± 0.036	4.184AspSer: 4.184 ± 0.037	2.936AspThr: 2.936 ± 0.026	3.67AspVal: 3.67 ± 0.029	0.863AspTrp: 0.863 ± 0.015	1.676AspTyr: 1.676 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	5.246GluAla: 5.246 ± 0.043	0.599GluCys: 0.599 ± 0.01	4.363GluAsp: 4.363 ± 0.041	6.056GluGlu: 6.056 ± 0.065	1.992GluPhe: 1.992 ± 0.02	3.812GluGly: 3.812 ± 0.034	1.378GluHis: 1.378 ± 0.021	3.298GluIle: 3.298 ± 0.029	4.053GluLys: 4.053 ± 0.041	5.254GluLeu: 5.254 ± 0.037	1.428GluMet: 1.428 ± 0.017	2.466GluAsn: 2.466 ± 0.027	2.867GluPro: 2.867 ± 0.038	2.579GluGln: 2.579 ± 0.031	4.257GluArg: 4.257 ± 0.039	4.57GluSer: 4.57 ± 0.039	3.663GluThr: 3.663 ± 0.034	3.499GluVal: 3.499 ± 0.031	0.871GluTrp: 0.871 ± 0.016	1.766GluTyr: 1.766 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	2.898PheAla: 2.898 ± 0.025	0.556PheCys: 0.556 ± 0.01	2.236PheAsp: 2.236 ± 0.023	2.153PheGlu: 2.153 ± 0.026	1.663PhePhe: 1.663 ± 0.023	2.735PheGly: 2.735 ± 0.033	0.925PheHis: 0.925 ± 0.015	1.85PheIle: 1.85 ± 0.023	1.443PheLys: 1.443 ± 0.016	3.642PheLeu: 3.642 ± 0.036	0.765PheMet: 0.765 ± 0.012	1.376PheAsn: 1.376 ± 0.019	2.065PhePro: 2.065 ± 0.02	1.409PheGln: 1.409 ± 0.019	2.019PheArg: 2.019 ± 0.021	3.149PheSer: 3.149 ± 0.027	2.091PheThr: 2.091 ± 0.021	2.364PheVal: 2.364 ± 0.026	0.643PheTrp: 0.643 ± 0.013	1.153PheTyr: 1.153 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.13GlyAla: 5.13 ± 0.042	0.813GlyCys: 0.813 ± 0.016	3.612GlyAsp: 3.612 ± 0.031	3.708GlyGlu: 3.708 ± 0.033	2.764GlyPhe: 2.764 ± 0.028	5.343GlyGly: 5.343 ± 0.051	1.657GlyHis: 1.657 ± 0.018	3.585GlyIle: 3.585 ± 0.032	3.499GlyLys: 3.499 ± 0.032	5.951GlyLeu: 5.951 ± 0.039	1.44GlyMet: 1.44 ± 0.019	2.552GlyAsn: 2.552 ± 0.028	3.431GlyPro: 3.431 ± 0.028	2.553GlyGln: 2.553 ± 0.024	4.219GlyArg: 4.219 ± 0.037	5.817GlySer: 5.817 ± 0.05	3.912GlyThr: 3.912 ± 0.032	4.23GlyVal: 4.23 ± 0.037	1.122GlyTrp: 1.122 ± 0.016	2.164GlyTyr: 2.164 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.737HisAla: 1.737 ± 0.019	0.316HisCys: 0.316 ± 0.008	1.275HisAsp: 1.275 ± 0.016	1.35HisGlu: 1.35 ± 0.018	0.901HisPhe: 0.901 ± 0.015	1.699HisGly: 1.699 ± 0.019	0.821HisHis: 0.821 ± 0.019	1.283HisIle: 1.283 ± 0.018	0.868HisLys: 0.868 ± 0.014	2.194HisLeu: 2.194 ± 0.021	0.481HisMet: 0.481 ± 0.011	0.808HisAsn: 0.808 ± 0.013	1.661HisPro: 1.661 ± 0.02	0.906HisGln: 0.906 ± 0.016	1.578HisArg: 1.578 ± 0.021	1.812HisSer: 1.812 ± 0.02	1.192HisThr: 1.192 ± 0.017	1.408HisVal: 1.408 ± 0.019	0.338HisTrp: 0.338 ± 0.009	0.704HisTyr: 0.704 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.056IleAla: 4.056 ± 0.033	0.775IleCys: 0.775 ± 0.014	2.957IleAsp: 2.957 ± 0.028	2.967IleGlu: 2.967 ± 0.027	2.079IlePhe: 2.079 ± 0.027	3.18IleGly: 3.18 ± 0.031	1.239IleHis: 1.239 ± 0.018	2.686IleIle: 2.686 ± 0.03	2.216IleLys: 2.216 ± 0.023	4.765IleLeu: 4.765 ± 0.041	1.017IleMet: 1.017 ± 0.015	1.81IleAsn: 1.81 ± 0.02	3.248IlePro: 3.248 ± 0.028	1.919IleGln: 1.919 ± 0.021	2.996IleArg: 2.996 ± 0.026	4.163IleSer: 4.163 ± 0.033	2.756IleThr: 2.756 ± 0.03	3.265IleVal: 3.265 ± 0.032	0.75IleTrp: 0.75 ± 0.015	1.528IleTyr: 1.528 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	4.167LysAla: 4.167 ± 0.035	0.481LysCys: 0.481 ± 0.012	2.854LysAsp: 2.854 ± 0.026	3.728LysGlu: 3.728 ± 0.037	1.421LysPhe: 1.421 ± 0.02	3.028LysGly: 3.028 ± 0.033	1.066LysHis: 1.066 ± 0.015	2.365LysIle: 2.365 ± 0.023	3.449LysLys: 3.449 ± 0.051	4.081LysLeu: 4.081 ± 0.033	0.974LysMet: 0.974 ± 0.015	1.802LysAsn: 1.802 ± 0.018	2.672LysPro: 2.672 ± 0.026	1.885LysGln: 1.885 ± 0.02	3.596LysArg: 3.596 ± 0.033	3.544LysSer: 3.544 ± 0.035	2.842LysThr: 2.842 ± 0.026	2.813LysVal: 2.813 ± 0.031	0.652LysTrp: 0.652 ± 0.013	1.414LysTyr: 1.414 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.393LeuAla: 7.393 ± 0.049	1.183LeuCys: 1.183 ± 0.017	5.139LeuAsp: 5.139 ± 0.035	5.554LeuGlu: 5.554 ± 0.045	3.41LeuPhe: 3.41 ± 0.034	5.718LeuGly: 5.718 ± 0.04	2.17LeuHis: 2.17 ± 0.024	4.013LeuIle: 4.013 ± 0.037	4.258LeuLys: 4.258 ± 0.029	8.4LeuLeu: 8.4 ± 0.059	1.726LeuMet: 1.726 ± 0.018	3.127LeuAsn: 3.127 ± 0.027	5.461LeuPro: 5.461 ± 0.037	3.799LeuGln: 3.799 ± 0.033	6.067LeuArg: 6.067 ± 0.04	7.707LeuSer: 7.707 ± 0.047	4.749LeuThr: 4.749 ± 0.038	5.26LeuVal: 5.26 ± 0.037	1.197LeuTrp: 1.197 ± 0.016	2.456LeuTyr: 2.456 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.09MetAla: 2.09 ± 0.021	0.23MetCys: 0.23 ± 0.007	1.225MetAsp: 1.225 ± 0.017	1.294MetGlu: 1.294 ± 0.018	0.728MetPhe: 0.728 ± 0.013	1.406MetGly: 1.406 ± 0.018	0.439MetHis: 0.439 ± 0.011	0.974MetIle: 0.974 ± 0.015	0.973MetLys: 0.973 ± 0.014	1.772MetLeu: 1.772 ± 0.018	0.536MetMet: 0.536 ± 0.011	0.76MetAsn: 0.76 ± 0.014	1.132MetPro: 1.132 ± 0.016	0.821MetGln: 0.821 ± 0.014	1.259MetArg: 1.259 ± 0.017	1.855MetSer: 1.855 ± 0.02	1.25MetThr: 1.25 ± 0.017	1.227MetVal: 1.227 ± 0.016	0.247MetTrp: 0.247 ± 0.006	0.503MetTyr: 0.503 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.075AsnAla: 3.075 ± 0.03	0.43AsnCys: 0.43 ± 0.01	1.952AsnAsp: 1.952 ± 0.021	2.119AsnGlu: 2.119 ± 0.025	1.318AsnPhe: 1.318 ± 0.019	3.015AsnGly: 3.015 ± 0.031	0.823AsnHis: 0.823 ± 0.015	2.084AsnIle: 2.084 ± 0.023	1.557AsnLys: 1.557 ± 0.017	3.201AsnLeu: 3.201 ± 0.026	0.79AsnMet: 0.79 ± 0.013	1.488AsnAsn: 1.488 ± 0.024	2.472AsnPro: 2.472 ± 0.027	1.307AsnGln: 1.307 ± 0.019	2.067AsnArg: 2.067 ± 0.023	2.68AsnSer: 2.68 ± 0.024	2.122AsnThr: 2.122 ± 0.025	2.331AsnVal: 2.331 ± 0.021	0.546AsnTrp: 0.546 ± 0.012	1.071AsnTyr: 1.071 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.186ProAla: 5.186 ± 0.045	0.496ProCys: 0.496 ± 0.011	3.296ProAsp: 3.296 ± 0.03	4.081ProGlu: 4.081 ± 0.038	2.114ProPhe: 2.114 ± 0.022	4.049ProGly: 4.049 ± 0.036	1.31ProHis: 1.31 ± 0.017	2.492ProIle: 2.492 ± 0.021	2.621ProLys: 2.621 ± 0.03	4.789ProLeu: 4.789 ± 0.031	1.007ProMet: 1.007 ± 0.015	2.138ProAsn: 2.138 ± 0.024	5.121ProPro: 5.121 ± 0.067	2.478ProGln: 2.478 ± 0.032	3.587ProArg: 3.587 ± 0.034	6.298ProSer: 6.298 ± 0.053	3.783ProThr: 3.783 ± 0.033	3.701ProVal: 3.701 ± 0.03	0.76ProTrp: 0.76 ± 0.014	1.592ProTyr: 1.592 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.216GlnAla: 3.216 ± 0.029	0.422GlnCys: 0.422 ± 0.011	2.027GlnAsp: 2.027 ± 0.021	2.569GlnGlu: 2.569 ± 0.028	1.289GlnPhe: 1.289 ± 0.016	2.363GlnGly: 2.363 ± 0.027	1.005GlnHis: 1.005 ± 0.017	1.902GlnIle: 1.902 ± 0.021	2.142GlnLys: 2.142 ± 0.024	3.412GlnLeu: 3.412 ± 0.03	0.882GlnMet: 0.882 ± 0.013	1.6GlnAsn: 1.6 ± 0.02	2.497GlnPro: 2.497 ± 0.031	2.385GlnGln: 2.385 ± 0.047	2.766GlnArg: 2.766 ± 0.03	3.201GlnSer: 3.201 ± 0.032	2.305GlnThr: 2.305 ± 0.024	2.062GlnVal: 2.062 ± 0.021	0.538GlnTrp: 0.538 ± 0.012	1.158GlnTyr: 1.158 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.722ArgAla: 4.722 ± 0.037	0.744ArgCys: 0.744 ± 0.016	3.509ArgAsp: 3.509 ± 0.035	4.179ArgGlu: 4.179 ± 0.045	2.252ArgPhe: 2.252 ± 0.025	3.844ArgGly: 3.844 ± 0.034	1.564ArgHis: 1.564 ± 0.021	3.085ArgIle: 3.085 ± 0.025	3.654ArgLys: 3.654 ± 0.036	5.597ArgLeu: 5.597 ± 0.041	1.294ArgMet: 1.294 ± 0.015	2.384ArgAsn: 2.384 ± 0.024	3.699ArgPro: 3.699 ± 0.038	2.729ArgGln: 2.729 ± 0.027	5.537ArgArg: 5.537 ± 0.054	5.239ArgSer: 5.239 ± 0.051	3.402ArgThr: 3.402 ± 0.032	3.477ArgVal: 3.477 ± 0.028	0.957ArgTrp: 0.957 ± 0.014	1.786ArgTyr: 1.786 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	6.778SerAla: 6.778 ± 0.047	0.872SerCys: 0.872 ± 0.014	4.414SerAsp: 4.414 ± 0.041	4.403SerGlu: 4.403 ± 0.036	3.15SerPhe: 3.15 ± 0.032	5.666SerGly: 5.666 ± 0.04	1.972SerHis: 1.972 ± 0.022	4.122SerIle: 4.122 ± 0.03	3.866SerLys: 3.866 ± 0.036	7.45SerLeu: 7.45 ± 0.048	1.682SerMet: 1.682 ± 0.018	3.066SerAsn: 3.066 ± 0.03	5.729SerPro: 5.729 ± 0.058	3.382SerGln: 3.382 ± 0.037	5.503SerArg: 5.503 ± 0.049	9.476SerSer: 9.476 ± 0.082	5.584SerThr: 5.584 ± 0.045	4.782SerVal: 4.782 ± 0.033	1.095SerTrp: 1.095 ± 0.018	2.153SerTyr: 2.153 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	5.184ThrAla: 5.184 ± 0.038	0.694ThrCys: 0.694 ± 0.012	2.881ThrAsp: 2.881 ± 0.03	3.195ThrGlu: 3.195 ± 0.033	2.182ThrPhe: 2.182 ± 0.021	4.16ThrGly: 4.16 ± 0.032	1.208ThrHis: 1.208 ± 0.019	3.044ThrIle: 3.044 ± 0.027	2.594ThrLys: 2.594 ± 0.025	5.046ThrLeu: 5.046 ± 0.037	1.161ThrMet: 1.161 ± 0.017	1.991ThrAsn: 1.991 ± 0.023	4.208ThrPro: 4.208 ± 0.04	1.969ThrGln: 1.969 ± 0.021	3.139ThrArg: 3.139 ± 0.025	5.236ThrSer: 5.236 ± 0.041	4.083ThrThr: 4.083 ± 0.042	3.856ThrVal: 3.856 ± 0.034	0.777ThrTrp: 0.777 ± 0.014	1.632ThrTyr: 1.632 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	4.968ValAla: 4.968 ± 0.04	0.81ValCys: 0.81 ± 0.014	3.735ValAsp: 3.735 ± 0.028	3.836ValGlu: 3.836 ± 0.034	2.397ValPhe: 2.397 ± 0.026	3.887ValGly: 3.887 ± 0.033	1.38ValHis: 1.38 ± 0.019	3.112ValIle: 3.112 ± 0.028	2.881ValLys: 2.881 ± 0.028	5.503ValLeu: 5.503 ± 0.04	1.256ValMet: 1.256 ± 0.017	2.192ValAsn: 2.192 ± 0.025	3.73ValPro: 3.73 ± 0.029	2.347ValGln: 2.347 ± 0.024	3.507ValArg: 3.507 ± 0.027	4.894ValSer: 4.894 ± 0.034	3.519ValThr: 3.519 ± 0.031	4.131ValVal: 4.131 ± 0.04	0.811ValTrp: 0.811 ± 0.016	1.749ValTyr: 1.749 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.029TrpAla: 1.029 ± 0.017	0.179TrpCys: 0.179 ± 0.007	0.885TrpAsp: 0.885 ± 0.014	0.862TrpGlu: 0.862 ± 0.015	0.531TrpPhe: 0.531 ± 0.011	0.89TrpGly: 0.89 ± 0.013	0.347TrpHis: 0.347 ± 0.01	0.779TrpIle: 0.779 ± 0.016	0.805TrpLys: 0.805 ± 0.012	1.315TrpLeu: 1.315 ± 0.02	0.357TrpMet: 0.357 ± 0.008	0.629TrpAsn: 0.629 ± 0.012	0.589TrpPro: 0.589 ± 0.012	0.553TrpGln: 0.553 ± 0.01	0.96TrpArg: 0.96 ± 0.013	1.013TrpSer: 1.013 ± 0.016	0.884TrpThr: 0.884 ± 0.014	0.828TrpVal: 0.828 ± 0.016	0.277TrpTrp: 0.277 ± 0.009	0.43TrpTyr: 0.43 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.142TyrAla: 2.142 ± 0.027	0.408TyrCys: 0.408 ± 0.01	1.693TyrAsp: 1.693 ± 0.022	1.622TyrGlu: 1.622 ± 0.02	1.206TyrPhe: 1.206 ± 0.019	2.174TyrGly: 2.174 ± 0.028	0.759TyrHis: 0.759 ± 0.013	1.539TyrIle: 1.539 ± 0.018	1.093TyrLys: 1.093 ± 0.017	2.718TyrLeu: 2.718 ± 0.028	0.632TyrMet: 0.632 ± 0.012	1.117TyrAsn: 1.117 ± 0.018	1.624TyrPro: 1.624 ± 0.022	1.113TyrGln: 1.113 ± 0.017	1.735TyrArg: 1.735 ± 0.018	2.128TyrSer: 2.128 ± 0.027	1.594TyrThr: 1.594 ± 0.019	1.697TyrVal: 1.697 ± 0.019	0.427TyrTrp: 0.427 ± 0.01	0.996TyrTyr: 0.996 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9264 proteins (4547040 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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